Medicine and Health Sciences Commons^™

Health Care Reform In The United States, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

The author presents a brief description of the design features and objectives of the health care reform package, together with the reasons to support reform of the health care system in the United States.

Biomedicine And Bioethics: De Lege Lata, De Lege Ferenda, George P. Smith Ii

Scholarly Articles

No abstract provided.

Tabaco, Ambiente Y Salud. La Situación En Venezuela Y El Mundo, Aldemaro Romero Jr.

Publications and Research

No abstract provided.

Model Consent Forms For Dna Linkage Analysis And Storage, Roger B. Dworkin, R. L. Gold, R. R. Lebel, E. A. Mearns, T Hadro, J. K. Burns

Articles by Maurer Faculty

No abstract provided.

Independence In The Elderly: A Review Of Activity Theory And Its Application, Michelle Dean

Whittier Scholars Program

Activity Theory is a major social theory in gerontology. Gerontology is a multidisciplinary approach to the study of aging individuals which combines fields such as biology, medicine, biochemistry, sociology, and psychology. This presentation will investigate causes of aging and the life cycle of aging individuals. A brief description of the major social theories of aging and their implications for life satisfaction in the culture of the American society will provide an introduction to the primary objective, which is independence in the elderly and the application of Activity theory. The outcome of this study and future concerns for research in gerontology …

Lattice Boltzmann Thermohydrodynamics, F. J. Alexander, S. Chen, J. D. Sterling

Business and Information Technology Faculty Research & Creative Works

We introduce a lattice Boltzmann computational scheme capable of modeling thermohydrodynamic flows of monatomic gases. The parallel nature of this approach provides a numerically efficient alternative to traditional methods of computational fluid dynamics. The scheme uses a small number of discrete velocity states and a linear, single-time relaxation collision operator. Numerical simulations in two dimensions agree well with exact solutions for adiabatic sound propagation and Couette flow with heat transfer. © 1993 The American Physical Society.

Simian Immunodeficiency Virus (Siv(Mac)251) Membrane Lipid Mixing With Human Cd4+ And Cd4- Cell Lines In Vitro Does Not Necessarily Result In Internalization Of The Viral Core Proteins And Productive Infection, L. Stamatatos, Nejat Düzgüneş

All Dugoni School of Dentistry Faculty Articles

The cell binding site of simian immunodeficiency virus (SIV) is believed to be the CD4 molecule. Several CD4+ cell lines are, however, resistant to infection by SIV(mac)251 in vitro and additional cell membrane molecules have been implicated in SIV(mac)251 entry. We investigated the binding, envelope fusion and entry of the viral core proteins (p27) of SIV(mac)251 into two human CD4+ cell lines (H9 and Sup-T1) which are infectible, and one CD4+ (A3.01) and two CD4- cell lines (K562 and Raji) that are resistant to infection. The fusion of the viral and cellular membranes was monitored by a fluorescence assay for …

Book Review: The Baculovirus Expression System: A Laboratory Guide (1992) King, L. A. & Possee, R. D., David D. Dunigan

Nebraska Center for Virology: Faculty Publications

The power of molecular biology is unleashed with the ability to clone and sequence genes, and then express these genes in heterologous systems. This sets the stage for the full analysis of proteins that are otherwise difficult to isolate and/or purify, especially when present at very low copy number per cell or when isolated from relatively precious materials. Overexpression of protein is now possible in a number of systems including prokaryotes (e.g., E. coli) and various eukaryotes (yeast, insects, and plants). The issue then becomes, which system (1) most closely reflects the homologous expression with respect to posttranslational modifications, …

Detection Of Serum Antibody Responses In Cattle With Natural Or Experimental Neospora Infections, Patricia Conrad, Karen Sverlow, Mark Anderson, Joan Rowe, Robert Bondurant, Gwen Tuter, Richard Breitmeyer, California Department Of Food And Agriculture, Animal Health Branch, Mark Thurmond, Alex Ardans, J. P. Dubey, Gerarld Duhamel, Bradd Barr

School of Veterinary and Biomedical Sciences: Faculty Publications

Parasite-specific antibody responses were detected using an indirect fluorescent antibody (IFA) test in cattle that were naturally or experimentally infected with Neospora parasites. The test was developed using Neospora tachyzoites isolated from an aborted bovine fetus and grown in bovine cell cultures (isolate BPA1). In all cases, infections were confirmed by the identification of Neospora tachyzoites and/or bradyzoite cysts in fetal or calf tissues using an immunoperoxidase test procedure. Fifty-five naturally infected cows that aborted Neospora-infected fetuses had titers of 320-5,120 at the time of abortion. The titer of 6 cows that were serologically monitored over a prolonged period decreased …

Preventive Interventions In Early Adolescence: Developmental And Contextual Challenges, Bonnie L. Barber, Lisa J. Crockett

Department of Psychology: Faculty Publications

Adolescence today is broadly perceived as a more difficult and dangerous period than in previous decades. Those holding this view point to increases in teenage pregnancy and childbearing, sexually transmitted diseases, alcohol abuse, drug addiction, juvenile arrests, depression, and suicide as indicators of changing conditions. Although uncommon in childhood, these problems increase in early adolescence, and they can lead to greater likelihood of negative developmental trajectories. Because young adolescents are at the age when these issues are surfacing, they are a particularly important target group for interventions designed to prevent or delay the onset of negative behavior patterns (Crockett & …

“Introduction” To Developmental Perspectives On Motivation, Janis Jacobs

Department of Psychology: Faculty Publications

This volume marks the 40th anniversary of the Nebraska Symposium on Motivation, and with it a renewed commitment to the Symposium's original focus on motivation. Although we may reemphasize the topic, it is clear that motivation, as an area of study, has changed dramatically over the past 40 years. Although motivation has remained an important theme, it has had to share the stage with other important topics as the field of psychology has expanded. In addition, the concept of motivation has been applied to many diverse areas, has been defined and measured in a variety of ways, and has been …

Colorectal Cancer., Lester Rosen Md, Facs

Department of Surgery

No abstract provided.

Effects Of Aerobic Training In Adolescents With Down Syndrome, A. Lynn Millar, Bo Fernhall, Lee N. Burkett

Faculty Publications

The purpose of this study was to evaluate the effects that aerobic training has on adolescents and young adults with Down syndrome. Fourteen individuals with Down syndrome (mean age = 17.7 yr) participated in a 10-wk walking/jogging exercise training study. A pre- and post-training walking treadmill test was performed to determine the following parameters: peak oxygen uptake (VO2, absolute and relative), minute ventilation (VE, l•min-1), heart rate HR, b•min-1), RER (VCO2/VO2), and time and grade to exhaustion. Following the pre-training evaluations, subjects were assigned to a control group (N = 4) or an exercise group (N= 10). The exercise group …

Effect Of Alcohol On The Postnatal Development Of Cerebellar Cortex In Rat Guste 1-Histological And Morphometric Studies., Mansoor Saleh, M N. Saleh, M A. Desouky, Saadia Sayed, Entesar Saber

Haematology and Oncology, East Africa

The effect of ethyl alcohol (10%) on the postnatal development of cerebellar cortex was studied using histological and morphometric methods. The external granular layer was much increased in thickness in alcohol fed rat than those of the control while the molecular and granular layer were reduced. The cells of themolecular layer showed neuronal degeneration and many spaces were present in this layer esp < /strong>ecially late postnatal. The Purkinje cells failed to reach their final position up the tenth day and still arranged in more than one row. The degenerative changes appeared at five days and increased with age. The extent …

Evaluation Of The Provision For A University Health Service As Part Of The Quality Assurance Process, Rob Chandler, Barry Sheridan

Research outputs pre 2011

Universities within Australia are facing increasing demands to demonstrate quality in both product and process by ensuing that their aims are met efficiently and effectively. As part of the quality assurance process for Edith Cowan University, a multi-campus institution, an evaluation was undertaken to monitor the effectiveness of the University health service and its significance within the University community. Responses from both staff and students to a survey conducted during August 1993 on behalf of the Department of Medical and Health Services indicate a high level of support for this service. This Report provides an overview of the evaluation study …

Persistent Emotional Disorder In Children With Neurological Soft Signs, Daniel Pine, David Shaffer, Irvin Sam Schonfeld

Publications and Research

Provides clinical details in the form of 11 case vignettes from a prospective epidemiological study that found the combination of childhood 'soft' signs and anxious behavior to be a strong risk factor for adolescent emotional disorders. The original study conducted a neuropsychiatric assessment of 180 African-American adolescents (aged 16–18 yrs) who had been followed through childhood. The at-risk Ss exhibited a persistent and specific pattern of both motor abnormalities and anxiety, obsessional compulsive, or depressive symptoms over time. The form of at-risk Ss' neurological and psychiatric abnormalities is consistent with a link between motor system abnormalities and …

Market And Non-Market Mechanisms For Procuring Human And Cadaveric Organs: When The Price Is Right, George P. Smith Ii

Scholarly Articles

In the United States, as well as throughout the world, current demands for organ transplants far exceed the actual supply. Nonconsensual human donations, taken from minors, incompetents and prisoners are regulated carefully by the courts. The Uniform Anatomical Gift Act and the National Organ Transplant Act serve also as statutory frameworks for organ retrievals and allocations and place various restrictions upon each. Altruistically motivated donations at death continue to be an inadequate mechanism for meeting the growing demands of the market. Included among the various approaches to resolving the critical shortage of human organs for transplantation are post mortem harvesting, …

The Legal Dilemma Of Partner Notification During The Hiv Epidemic, Raymond C. O'Brien

Scholarly Articles

No abstract provided.

Reviving The Swan, Extending The Curse Of Methuselah, Or Adhering To The Kevorkian Ethic?, George P. Smith Ii

Scholarly Articles

No abstract provided.

The Shaman's Destiny: Symptoms, Affliction, And The Re-Interpretation Of Illness Among The Taman, Jay H. Bernstein

Publications and Research

No abstract provided.

Trypanosoma (Nannomonas) Congolense: Molecular Characterization Of A New Genotype From Tsavo, Kenya, P. A.O. Majiwa, M. Maina, J. N. Waitumbi, S. Mihok, E. Zweygarth

All Peer-Reviewed Publications

Trypanosoma (Nannomonas) congolense comprises morphologically identical but genetically heterogeneous parasites infective to livestock and other mammalian hosts; three different genotypes of this parasite have been described previously. Restriction enzyme fragment length polymorphisms (RFLPs) in both kinetoplast DNA minicircle and nuclear DNA sequences, and randomly amplified polymorphic deoxyribonucleic acid (RAPD) patterns have been used here to demonstrate the existence of another type of T. (N.) congolense that is genotypically distinct from those that have so far been characterized at the molecular level. A highly repetitive, tandemly arranged DNA sequence and oligonucleotide primers, for use in polymerase chain reaction (PCR) amplification are …

Cysticercosis In A Muslim Woman, Farrukh Aijaz, Altaf Ahmed

Department of Pathology and Laboratory Medicine

No abstract provided.

Factor Xiii Deficiency In Pakistan, Aamir Nadeem Shaikh, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Patients with undiagnosed haemostatic defects seen at The Aga Khan Hospital and Fatimid Blood Transfusion Centre during the period of 7 years (1 985-1 992) were screened with routine tests including bleeding time (BT), whole blood clotting time (CT), platelet count, activated partial thromboplastin time (APTT), prothrombin time (PT) and 5 molar urea test. Nine patients had a positive 5 molar urea test indicating factor XIII deficiency. Rest of the screening tests were normal in these patients. High incidence of consanguinity was observed in affected families. Clinical features included excessive bleeding from umbilical stump, bruising, post-traumatic bleeding, epistaxis, melaena and …

Malabsorption Of Nutrients In Children With Diarrhoea Due To Unknown Aetiologies, Ayesha Molla, Mohammad Khurshid, Abdul Majid Molla, Makhduma Khatun

Department of Pathology and Laboratory Medicine

Intake and coefficient of absorption of nutrients wefe measured in 72 children dufing acute diarrhoea and 2 weeks after fecovery. No diarrhooeal pathogens could be identified in 18 (25%) childfen (group I). Aetiology of diafrhoea was identified in fest of the 54 children (group II). Absofption of oalofie, fat and cafbohydrate during the recovery stage were similaf in all 72 children, In group I, absorption of nutrients improved from acute stage to recovery stage as follows: fat from 62 to 85%, calofies from 68 to 86% and carbohydrate from 81 to 91%. Absorption of nitrogen during the acute stage was …

Cloning And Expression Of A Novel Na(+)-Dependent Neutral Amino Acid Transporter Structurally Related To Mammalian Na+/Glutamate Cotransporters, Saad Shafqat, Balaji Tamarappoo, Michael S Kilberg, Ram S Puranam, James O. Mcnamara, Ana Guadaño -Ferraz, R.T. Fremeau

Section of Neurology

A cDNA has been isolated from human hippocampus that appears to encode a novel Na(+)-dependent, Cl(-)-independent, neutral amino acid transporter. The putative protein, designated SATT, is 529 amino acids long and exhibits significant amino acid sequence identity (39-44%) with mammalian L-glutamate transporters. Expression of SATT cDNA in HeLa cells induced stereospecific uptake of L-serine, L-alanine, and L-threonine that was not inhibited by excess (3 mM) 2-(methylamino)-isobutyric acid, a specific substrate for the System A amino acid transporter. SATT expression in HeLa cells did not induce the transport of radiolabeled L-cysteine, L-glutamate, or related dicarboxylates. Northern blot hybridization revealed high levels …

Molecular Characterization Of Neurotransmitter Transporters, Saad Shafqat, M Velaz- Faircloth, A Guadaño- -Ferraz, R T Fremeau

Section of Neurology

No abstract provided.

Foreword: Health Care Reform In The United States—The Presidential Task Force, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

This essay serves as the foreword to Implementing U.S. Health Care Reform, a symposium held in 1993.

The exact specifications of the new health care system depend on the package that President Clinton will send to Capitol Hill and the changes that Congress will make in the reform package. Some of the basic structures and organizing principles of the new system that are being considered by the President are already the subject of intense public scrutiny.

The design being considered would involve new relations between the federal government and the states, between the public and private sectors, and between …

Management Of Diabetic Patient’S Undergoing Major Surgery Using Glucose Insulin Potassium Infusion, Fazal Hameed Khan, Rs Kamal

Department of Anaesthesia

No abstract provided.

Epidermal Mosaicism And Blaschko's Lines, Celia Moss, S. Larkins, Michael W. Stacey, A. Blight, P. A. Farndon, E. V. Davidson

Bioelectrics Publications

To test the hypothesis that epidermal rather than dermal mosaicism determines Blaschko's lines in hypomelanosis of Ito (HI), we studied the distribution of chromosomal mosaicism in four patients. In two, mosaicism had not been detected in lymphocytes or dermal fibroblasts, but was clearly shown in epidermal keratinocytes; furthermore, the abnormal cell line was confirmed to the hypopigmented epidermis and the normal epidermis contained only normal cells. Negative findings in the other two patients might be because of mosaicism which was undetected either because it was submicroscopic or because it was present in melanocytes, which have not yet been studied. These …

Experimental Immunity Against Trypanosomiasis In Rabbits, Curtis Powell

All Peer-Reviewed Publications

Rabbits were immunized with specially prepared subcellular fractions of a cloned Trypanosoma brucei brucei stock 427. One fraction was found to be highly immunoprophylactic in rabbits exposed to the vector fly genus Glossina m. morsitans (tsetse flies) infected with EATRO Trypanosoma brucei brucei 1969. The most immunoprotective fraction IPFA from T. b. brucei 427 gave 75% protection to animals challenged by EATRO T. b. brucei 1969. IPFA also showed the highest IgG antibody titre against the heterologous and homologous strains. In in vitro studies, the sera from these immunized rabbits killed different strains of parasites, T. b. brucei strains 1969 …