Medicine and Health Sciences Commons^™

If Deliberative Democracy Is The Solution, What Is The Problem?, Emily Hauptmann

Center for the Study of Ethics in Society Papers

Presented March 18, 1999 for the Center for the Study of Ethics in Society.

A Longitudinal Examination Of The Consequences Of Sexual Victimization For Rural Young Adult Women, Janine Zweig, Lisa J. Crockett, Aline Sayer, Judith Vicary

Department of Psychology: Faculty Publications

This longitudinal study examined the consequences of sexual victimization in a sample of 237 young adult women from a rural community. Of the total sample, 71 (30%) reported experiencing some type of unwanted sex. Multiple regression was used to examine the effects on psychosocial adjustment of unwanted sex that occurred through nonviolent coercion and violent coercion, respectively, controlling for prior psychological adjustment. Results indicated that women who reported physically violent sexual coercion exhibited poorer psychological and social/relational adjustment than either nonvictimized women or women who had experienced nonviolent forms of sexual coercion. Additionally, nonviolent sexual coercion was associated with higher …

Wellness Center Healthletter - November 1999, Nova Southeastern University

Wellness Center Healthletter

No abstract provided.

Construct Validity Of The Continuous Recognition Memory Test, K. L. Fuchs, J. H. Hannay, W. M. Huckeba, K. A. Espy

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

A principal factor analysis was performed on variables derived from a neuropsychological battery administered to 100 healthy young adults (aged 17-41 yrs) to investigate the construct validity of the Continuous Recognition Memory test (CRM). It was hypothesized that CRM "hits" and "false alarms" would load on different factors. The factors that emerged in the analysis were labeled Verbal Ability, Divided Attention, Attention to Visual Detail, Visuomotor Integration and Planning, and Learning and Memory. As expected, CRM hits had a significant loading on the Learning and Memory factor. However, CRM false alarms did not have a significant loading on the Divided …

Neuropsychologic Function In Toddlers Exposed To Cocaine In Utero: A Preliminary Study, K. A. Espy, P. M. Kaufmann, M. L. Glisky

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

Patterns of neuropsychological performance on A-not-B, inhibition, motor, cognitive, language, and behavior tasks were examined in 34 toddlers--17 cocaine-exposed (CE) and 17 nonexposed (NE) controls. CE toddlers exhibited greater perseveration, less inhibition, poorer emotional regulation, and less task orientation relative to NE toddlers. Overall cognitive and language skills and motor impairment status were comparable among CE and NE toddlers. Differences in perseveration, emotional regulation, and task orientation between CE and NE toddlers remained significant after statistically controlling for overall cognitive skill. Prenatal cocaine exposure may impart selective vulnerability for deficits in executive function, inhibition, and emotional regulation in toddlers, perhaps …

Executive Functioning In Preschool Children: Performance On A-Not-B And Other Delayed Response Format Tasks, K. A. Espy, P. M. Kaufmann, M. D. Mcdiarmid, M. L. Glisky

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

The A-not-B (AB) task has been hypothesized to measure executive/frontal lobe function; however, the developmental and measurement characteristics of this task have not been investigated. The present study examined performance on AB and comparison tasks adapted from developmental and neuroscience literature in 117 1.9-5.5 yr old preschool children. Age significantly predicted performance on AB, Delayed Alternation, Spatial Reversal, Color Reversal, and Self-Control tasks. A 4-factor analytic model best fit task performance data. AB task indices loaded on 2 factors with measures from the Self-Control and Delayed Alternation tasks, respectively. AB indices did not load with those from the reversal tasks …

The Predictive Use Of Event-Related Potentials In Language Development And The Treatment Of Language Disorders, Dennis L. Molfese, Victoria J. Molfese, K. A. Espy

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

Attempts to relate what is currently known regarding the brain's involvement in language processing during the early years of life. The authors focus on the event related potential (ERP) as a means to study the neuroelectrical correlates of language in the brains of infants and children. After reviewing general information concerning ERPs and language, this presentation relates how neonatal ERP measures of phonetic discrimination predict later language and reading abilities.

The Public Stake In Biomedical Research: A Policy Perspective, Karen Matherlee

National Health Policy Forum

An introduction to a Forum series on biomedical research policy issues, this paper provides background on the organization and structure of both public and private research entities. It outlines the federal components, from the National Institutes of Health (NIH) to the Department of Veterans Affairs. It also looks at the rapid growth in pharmaceutical, biotechnology, and medical device research and development and the varying responses from managed care plans, practice-based research networks, and contract research organizations. After laying out various tensions in the field, such as competition among disease-oriented advocates, alignment of different priorities, allocation of dollars between basic and …

Evaluation And Management Of Gout, N S. Ali

Department of Family Medicine

No abstract provided.

The Current State Of Practice Administration Curricula In U.S. Dental Schools., Brian M. Lange, David G. Dunning, Denise C.L. Stewart, Jack L. Hardage

Journal Articles: College of Dentistry

No abstract provided.

Tracking Of Physical Activity, Physical Inactivity, And Health-Related Physical Fitness In Rural Youth, Russell R. Pate, Stewart G. Trost, Marsha Dowda, Alise E. Ott, Dianne S. Ward, Ruth P. Saunders, Gwen A. Felton

Faculty Publications

This study examined the tracking of selected measures of physical activity, inactivity, and fitness in a cohort of rural youth. Students (N=181, 54.7% female, 63.5% African American) completed test batteries during their fifth- (age=10.7±0.7 years), sixth-, and seventh-grade years. The Previous Day Physical Activity Recall (PDPAR) was used to assess 30-min blocks of vigorous physical activity (VPA), moderate-to-vigorous physical activity (MVPA), TV watching and other sedentary activities, and estimated energy expenditure (EE). Fitness measures included the PWC 170 cycle ergometer test, strength tests, triceps skinfold thickness, and BMI. Intraclass correlation coefficients (ICCs) for VPA, MVPA, and after-school EE …

Enhanced Apoptosis Mediates Inhibition Of Ebv-Transformed Lymphoblastoid Cell Line Proliferation By Curcumin., D Ranjan, T D Johnston, K S Reddy, G Wu, Subbarao Bondada, C Chen

Microbiology, Immunology, and Molecular Genetics Faculty Publications

BACKGROUND: Epstein-Barr virus (EBV)-associated B-cell lymphomas occur more frequently in immunodeficient states such as organ transplantation and HIV infection. We have previously reported that B cell immortalization with EBV was promoted by cyclosporin A (CyA) and that curcumin (Cur), a natural phenol with known antioxidant and antitumor properties, blocked EBV-induced B cell immortalization. In the following experiments we show that Cur inhibits the proliferation of EBV-transformed lymphoblastoid cell lines (LCL) via enhanced apoptosis.

METHODS: LCL were generated by infecting freshly isolated human B cells with EBV (B95-8) for 12 h and coculturing with predetermined optimal concentrations of CyA (500 ng/ml) …

Validity Of The Previous Day Physical Activity Recall (Pdpar) In Fifth-Grade Children, Stewart G. Trost, Dianne S. Ward, Ben Mcgraw, Russell R. Pate

Faculty Publications

This study evaluated the validity of the Previous Day Physical Activity Recall (PDPAR) self-report instrument in quantifying after-school physical activity behavior in fifth-grade children. Thirty-eight fifth-grade students (mean age, 10.8 ± 0.1; 52.6%; female; 26.3% African American) from two urban elementary schools completed the PDPAR after wearing a CSA WAM 7164 accelerometer for a day. The mean within-subject correlation between self-reported MET level and total counts for each 30-min block was 0.57 (95% C.I., 0.51-0.62). Self-reported mean MET level during the after-school period and the number of 30-min blocks with activity rated at > 6 METs were significantly correlated with the …

Optimization Of Solid-State Fermentation Parameters For The Production Of Xylanase By Trichoderma Longibrachiatum On Wheat Bran In A Forced Aeration System, Elizabeth R. Ridder, Sue E. Nokes, Barbara L. Knutson

Biosystems and Agricultural Engineering Faculty Publications

The effect of aeration on the production of xylanase by Trichoderma longibrachiatum on wheat bran in a solid-state fermentation (SSF) system has not been investigated. This study was conducted to investigate the interactive effects of aeration, initial moisture content of the substrate, and depth of the substrate on xylanase activity produced in a tray fermenter. The experiment was conducted as a split plot experiment with factorial treatments and three replications of each treatment combination. The whole plot treatment was aeration rate (0, 2.9, 5.7 L/min/kg bran). Initial moisture content (45, 55, 65% w.b.) and depth of substrate (1.0 and 2.5 …

Évaluation D'Un Dispositif De Captage À La Source Pour La Fabrication De Petites Pièces En Plastique Renforcé, Louis Lazure

Rapports de recherche scientifique

No abstract provided.

Bilan Des Analyses Environnementales Réalisées En Laboratoire : Portrait De La Situation Pour La Période 1994-1996, Claude Ostiguy, Pierre Larivière, Alain Lajoie

Rapports de recherche scientifique

No abstract provided.

Recherche De Facteurs De Comparaison Entre Les Systèmes D'Échantillonnage De Poussières Inhalables Et De Poussières Totales, Guy Perrault, Daniel Drolet, Zélie Fortin, Yves Cloutier

Rapports de recherche scientifique

No abstract provided.

La Sélection Et Le Développement De Gants De Protection Contre Les Lacérations Dans Le Secteur De La Fabrication Des Produits En Métal, Chantal Tellier, Jaime Lara, Renaud Daigle

Rapports de recherche scientifique

No abstract provided.

Four Clinical Tests Of Sacroiliac Joint Dysfunction: The Association Of Test Results With Innominate Torsion Among Patients With And Without Low Back Pain, Pamela Levangie

All PTHMS Faculty Publications

Background and Purpose. The purpose of this study was to assess the association between innominate torsion (asymmetric anteroposterior positioning of the pelvic innominates) and the Gillet, standing forward flexion, sitting forward flexion, and supine-to-sit tests. Subjects. A sample of 21- to 50-year-old patients with low back pain (n=150) and a comparison group of patients with upper-extremity impairments (n=138) were recruited from outpatient physical therapy facilities. Methods. The association of single and combined test results with innominate torsion (calculated from pelvic landmark data) and with presence or absence of low back pain were estimated via odds ratios, sensitivities, specificities, and predictive …

Mechanisms Of Gene Transfer Mediated By Lipoplexes Associated With Targeting Ligands Or Ph-Sensitive Peptides, Sérgio Simões, Vladimir Slepushkin, Pedro Pires, Rogério Gaspar, Maria C. Pedroso De Lima, Nejat Düzgüneş

All Dugoni School of Dentistry Faculty Articles

Association of a targeting ligand such as transferrin, or an endosome disrupting peptide such as GALA, with cationic liposome-DNA complexes ('lipoplexes') results in a significant enhancement of transfection of several cell types. Although these strategies can overcome some of the barriers to gene delivery by lipoplexes, the mechanisms by which they actually enhance transfection is not known. In studies designed to establish the targeting specificity of transferrin, we found that apo-transferrin enhances transfection to the same extent as transferrin, indicating that internalization of the lipoplexes is mostly independent of transferrin receptors. These observations were reinforced by results obtained from competitive …

Ethnic Variability In The Treatment Of Pain, Rafael A. Ortega, Benjamin A. Youdelman, Richard C. Havel

Department of Surgery Faculty Papers

Ethnicity has been shown to be an important determinant of behavior during illness, particularly when a painful condition is present. Studies have shown that pain may be undertreated among different ethnic groups of patients. Whereas individual variations in the reaction to pain occur, available data do not support racial and/or ethnic differences in the perception of pain, leaving no justification for this discrepancy in treatment. Regardless of ethnicity, inadequate treatment of pain has been known for some time and has been referred to in recent literature as "oligoanalgesia." Lack of understanding of different ethnic and cultural groups can lead to …

Immune Cd8+ T Cells Prevent Reactivation Of Toxoplasma Gondii Infection In The Immunocompromised Host, Imtiaz A. Khan, William R. Green, Lloyd H. Kasper, Kathy A. Green, Joseph D. Schwartzman

Dartmouth Scholarship

Toxoplasma gondii remains a serious cause of morbidity and mortality in individuals that are immunosuppressed, patients with AIDS in particular. The cellular immune response, especially by gamma interferon (IFN-γ)-producing CD8⁺ T cells, is an essential component of protective immunity against the parasite. In the present study the role of CD8⁺ T cells during the reactivation of Toxoplasma infection in an immunocompromised murine model was evaluated. Chronically infected mice were challenged with LP-BM5 virus, and the kinetics of CD8⁺ T-cell function was studied. At 10 weeks after viral infection, mice showed obvious signs of systemic illness and began …

Arthritis And Rosai-Dorfman Disease Of The Skin: A Diagnostic Dilemma, Irshad Nabi Soomro, Kamran Hameed

Department of Pathology and Laboratory Medicine

No abstract provided.

The Abcs Of Pbms, Robin J. Strongin

National Health Policy Forum

This issue brief describes the evolution of the pharmacy benefit manager (PBM) industry since the late 1960s and outlines current business practices in the areas of payment, services, drug formularies, and rebates. Tools of the trade, such as cost-sharing and generic substitution, used to control costs and improve quality are also discussed.

Update: West Nile Virus Encephalitis — New York, 1999, Centers For Disease Control And Prevention, Denis Nash

Publications and Research

The West Nile virus (WNV) encephalitis outbreak continues to wane in the Northeast with the onset of cooler temperatures and continued vector-control operations. This report updates the progress of the ongoing investigation. Since the last published update (1), five additional domestic human cases and one international case have been identified. As of October 19, 56 (31 confirmed and 25 probable) cases of WNV infection have been identified, including seven deaths (Figure 1). The date of onset of the latest cases was September 22. The international case was a Canadian citizen who had visited the New York City (NYC) area in …

Consistency And Development Of Prosocial Dispositions: A Longitudinal Study, Nancy Eisenberg, Ivanna K. Guthrie, Bridget C. Murphy, Stephanie A. Shepard, Amanda Cumberland, Gustavo Carlo

Department of Psychology: Faculty Publications

The issue of whether there is consistency in prosocial dispositions was examined with a longitudinal data set extending from ages 4 to 5 years into early adulthood (N = 32). Spontaneous prosocial behaviors observed in the preschool classroom predicted actual prosocial behavior, other- and self-reported prosocial behavior, self-reported sympathy, and perspective taking in childhood to early adulthood. Prosocial behaviors that were not expected to refl ect an other-orientation (i.e., low cost helping and compliant prosocial behavior) generally did not predict later prosocial behavior or sympathy. Sympathy appeared to partially mediate the relation of early spontaneous sharing to later prosocial dispositions. …

Chip And Medicaid Outreach And Enrollment: A Hands-On Look At Marketing And Applications, Judith D. Moore

National Health Policy Forum

The State Children's Health Insurance Program (SCHIP or CHIP), enacted as part of the Balanced Budget Act (BBA) in 1997, has enrolled eligible low-income children in innovative ways and tackled a variety of challenges to make sure that families know about the new program. This issue brief describes the outreach, application, and enrollment process for both SCHIP and Medicaid, analyzing the difficulty in simplifying applications, and noting problems that states must solve around systems design, immigration issues, and the stigma sometimes associated with government programs.

Ada News - 10/18/1999, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Increased Matrix Synthesis Following Adenoviral Transfer Of A Transforming Growth Factor Beta1 Gene Into Articular Chondrocytes, Franklin D. Shuler Md, Phd, Helga I. Georgescu, Christopher Niyibizi, Rebecca K. Studer, Zhibao Mi, Brian Johnstone, Paul D. Robbins, Christopher H. Evans

Orthopaedics

Monolayer cultures of lapine articular chondrocytes were transduced with first-generation adenoviral vectors carrying lacZ or transforming growth factor β₁ genes under the transcriptional control of the human cytomegalovirus early promoter. High concentrations of transforming growth factor β₁ were produced by chondrocytes following transfer of the transforming growth factor β₁ gene but not the lacZ gene. Transduced chondrocytes responded to the elevated endogenous production of transforming growth factor β₁ by increasing their synthesis of proteoglycan, collagen, and noncollagenous proteins in a dose-dependent fashion. The increases in collagen synthesis were not accompanied by alterations in the collagen phenotype; …

Synapse, Alabama Health Libraries Association

Synapse - Newsletter of ALHeLa

This is the Fall, 1999 edition of the ALHeLa newsletter - Synapse.

Contents include:

• President's Column
• ALHeLA 2000 officers
• ALHeLA 1999 achievement award
• ALHeLA 1999 annual meeting student award
• ALHeLA 1999 award winning essay - The Evolution of Medical Education And Library Support - C.J. Bryant
• Alabama Health Libraries Association - 1999 Executive Committee
• Alabama Health Libraries Association - Annual Business Meeting - Minutes