Medicine and Health Sciences Commons^™

Sirolimus-Tacrolimus Combination Immunosuppression., Vivian Mcalister, Zu-Hua Gao, Kevork Peltekian, Javier Domingues, Kamran Mahalati, Allan Macdonald

Data and Test Instruments

A series of 32 recipients of liver, kidney, or pancreas transplants who were treated with sirolimus and low-dose tacrolimus experienced a low rate of rejection and excellent graft function without drug-related toxic effects.

Canadian Medical Officers In The Royal Navy (Book Review), Vivian Mcalister

Data and Test Instruments

CANADIAN MEDICAL OFFICERS IN THE ROYAL NAVY -- WORLD WAR II. Harry Stafford Morton. 112 pp. Illust. Canadian Naval Memorial Trust, HMCS Sackville, PO Box 99000, Stn Forces, Halifax NS B3K 5X5. 2000. Can$18.00 At the beginning of the Second World War, the Royal Canadian Navy offered 90 medical officers on loan to the Royal Navy. The author was among that group, which included leaders in Canadian surgery such as Surgeon Lieutenant McLachlin of London, Ont. The history of these medical officers has not been written because it fell between histories of the Royal Canadian Navy and the Royal Navy. …

Relational Autonomy, Self-Trust, And Health Care For Patients Who Are Oppressed, Carolyn Mcleod, Susan Sherwin

Philosophy Publications

No abstract provided.

Ua60/5 Wku Dental Hygiene Class Of 2000, Wku Dental Hygiene

WKU Administration Documents

Members of the 2000 dental hygiene class: Emily Cook, Holly Cothron, Rhonda Craven, Belinda Curtis, Laura Hill, Amy Hiser, Charlene Pierce, Julie Ploetz, Anne Brady, Julie Lane, Hanna Winegar, Laura Greenwell, Tracey Surina, Nicole Franklin, Shannon Johnson, Hannah Dugger, DeVanna Garland, Tonya Joiner, Amy McCarty, Tracey Vanhook and Carmi Thompson.

Fish Health For Fish Farmers - 2nd Edition, Tina Thorne

Fisheries Published Reports

2nd edition.

Disease is a departure from the normal state of health of a fish or any other animal. Diseases have no doubt occurred among fishes since these animals have occupied a place on the earth. Scientific efforts to understand the causes of disease in fishes, and to attempt to control them however, have only been made during the last sixty years.

Fishes, crustaceans and molluscs, as with other animals are subject to a wide spectrum of diseases, that can be classified as infectious or non-infectious. The vast majority of disease problems in the intensive farming of aquatic animals can …

Utilization Of Global Attributions In Recognizing And Responding To Gender Discrimination Among College Women, Mindi D. Foster

Psychology Faculty Publications

Although learned helplessness theories suggest that global attributions for gender discrimination may serve to promote feelings of helplessness about responding to discrimination, group consciousness theories suggest they may instead be a precursor to enhancing collective actions against discrimination.

To examine this theoretical discrepancy, college women completed measures of attributions for gender discrimination, political consciousness (as measured by common fate), participation in collective action, and helplessness behavior among college women. To examine the unique role of global attributions, participants were included if they made external and unstable attributions for discrimination (N = 231). Structural equation modeling showed hat recognizing discrimination occurs …

Positive And Negative Responses To Personal Discrimination: Does Coping Make A Difference?, Mindi D. Foster

Psychology Faculty Publications

Although psychological research has found that perceiving personal discrimination is associated with negative psychological symptoms, group consciousness theories suggest that perceiving personal discrimination can be empowering. To attempt to reconcile these presumably opposing findings, the present study suggested that how one copes with perceiving personal discrimination may better predict whether the outcomes are negative or positive than the perception of personal discrimination alone. American female university students ( N = 262) completed a questionnaire assessing their perceptions of personal discrimination, psychological symptoms and psychosocial behaviors. A series of hierarchical regression analyses indicated that coping mechanisms predicted psychosocial behaviors over and …

The Effect Of A Suggestive Interview On Children’S Memory Of A Repeated Event: Does It Matter Whether Suggestions Are Linked To A Particular Incident?, Martine Powell, Kim P. Roberts, Donald M. Thomson

Psychology Faculty Publications

This study examined the impact of linking misleading information to a particular occurrence of a repeated event. Children aged 5- to 6-years took part in the same staged event four times and 16 target details varied in each occurrence (e.g., the colour of a cloak varied each time). Three days or three weeks later they were asked questions, some of which included false information, about the final occurrence. The next day, the children were required to recall what happened in the final occurrence. Compared to children whose biasing interview was not focused on any particular occurrence of the repeated event, …

An Updated Look At Depressive Symptoms And Job Satisfaction In First-Year Women Teachers, Irvin Sam Schonfeld

Publications and Research

This report updates a longitudinal study (I. S. Schonfeld, 1992) of the effects of working conditions on newly appointed womenteachers. The update included a later graduating cohort and additional outcome measures. Moreover, women who were not fully exposed to work stressors (e.g. part-time work, change of schools) were now excluded from the analyses. Among the 184 teachers (average age 27 yrs), work environment measures were more highly correlated with future depressive symptoms, self-esteem, job satisfaction, and motivation to teach than with pre-employment counterparts of the outcomes. Regression analyses underlined the effects of the work environment on …

Response To Critique Of The Claim Of Cannibalism At Cowboy Wash, Patricia M. Lambert, Banks L. Leonard, Brian R. Billman, Richard A. Marlar, Margaret E. Newman, Karl J. Reinhard

Karl Reinhard Publications

The original authors of Billman et af. (2000) are joined by three other analysts from the Cowboy Wash research team to respond to the critique of this article by Dongoske et af. (2000). Dongoske and his coauthors state that Billman et af. (2000) failed to test alternative hypotheses or to consider alternative explanations for the findings at 5MTJOOJO and similar sites. The original authors point out that alternative hypotheses were examined and rejected, leaving a violent episode of cannibalism as the most plausible explanation for the remains found at 5MTJOOJO. Dongoske et af. also question many aspects of the osteological, …

Realities And Treatment Of Rape, Alison S. Brennan

Graduate Research Papers

One in three women have experienced a sexual assault. The impact of sexual assault can affect numerous aspects of a woman's life including: sexual health, cognitions, behaviors, emotions, interpersonal relationships, and self-perceptions. The healing journey for a rape victim is often initiated with the aid of a counselor. For this reason alone, it is crucial for counselors to have a basic knowledge of the symptoms as well as the various treatments for rape victims.

Primary Isolation Of Ehrlichia Chaffeensis From Patients With Febrile Illnesses: Clinical And Molecular Characteristics, Steven M. Standaert, Tina Yu, Margie A. Scott, James E. Childs, Christopher D. Paddock, William L. Nicholson, Joseph Singleton Jr., Martin J. Blaser

Zoonotics and Wildlife Disease: Publications

Ehrlichia chaffeensis was sought among patients with a history of tick exposure and fever, and the accuracy of other diagnostic tests was compared with that of primary isolation. Among the 38 patients enrolled, E. chaffeensis was isolated from the blood of 7 (18%) and from cerebrospinal fluid specimens of 2 of these 7. All 7 patients also were positive by polymerase chain reaction (PCR) of blood, and 6 patients developed diagnostic titers of antibody to E. chaffeensis. The isolates were characterized by molecular analysis of the 16S rRNA gene, the 120-kDa protein gene, and the variable-length PCR target (VLPT) …

Expression Of Biologically Active Human Butyrylcholinesterase In The Cabbage Looper (Trichoplusia Ni), Peter L. Platteborze, Clarence A. Broomfield

United States Army: Publications

This investigation examined the utility of three recombinant protein-expression systems (COS cells, insect cells and insect larvae) to cost-effectively produce biologically active human butyrylcholinesterase (BuChE). It was determined that baculovirus-infected insect cells (Sf9 and High 5) expressed 3.5- and 8.2-fold, respectively, more active enzyme than COS-7 cells. Baculovirus-infected cabbage looper (Trichoplusia ni) insect larvae produced over 26 times more than High 5 cells ; in fact, one baculovirus-infected insect larva provided more active protein than 100 ml of insect cell culture. Analysis of the larvally expressed proteins revealed that the vast majority of BuChE expressed was inactive due to …

An Instructor's Guide To Electronic Databases Of Indexed Professional Literature, Scott T. Kidd, Cheryl L. Meyer, Brian M. Olesko

School of Professional Psychology Faculty Publications

This document reviews 20 databases that are relevant to psychology but that are used primarily by professionals in other disciplines. Each database is described, any corresponding paper index is indicated, searching tips are provided, and, when available, free Internet access sites are identified.

History, Religion And Meaning: American Reflections On The Holocuast And Israel, Jules Simon

Departmental Papers (Philosophy)

No abstract provided.

The Effects Of An Educational Intervention On Calcium Intake And Bone Mineral Content In Young Women With Low Calcium Intake., B. Peterson, R. Klesges, E. Kaufman, Theodore Cooper, C. Vukadonovich

Departmental Papers (Psych)

No abstract provided.

Mortality In Serologically Unconfirmed Mediterranean Spotted Fever [With Reply], Pablo Yagupsky, Christopher D. Paddock, James E. Childs, Sherif R. Zaki, Stephen A. Berger

Zoonotics and Wildlife Disease: Publications

I read with interest the article by Paddock et al. [1], who described the detection of occult mortality due to Rocky Mountain spotted fever (RMSF) by demonstrating Rickettsia rickettsii antigens or DNA in blood and tissues. In Mediterranean countries, including Israel, spotted fever is caused by members of the R. conorii complex, which are antigenically related to R. rickettsii. ...

To the Editor -- We appreciate the comments by Yagupsky, which underscore several of the salient features of spotted fever- group rickettsial infections that we emphasized in our report [2]. For patients, diagnosticians, and clinicians faced with the potentially tragic …

A Simple Method For Generating Full Length Cdna From Low Abundance Partial Genomic Clones, Yongxin Wang, Joseph M. Fugaro, Fauzia Siddiq, Chandra Mouli V. Goparaju, Fulvio Lonardo, Anil Wali, John F. Lechner, Harvey I. Pass

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

PCR amplification of target molecules involves sequence specific primers that flank the region to be amplified. While this technique is generally routine, its applicability may not be sufficient to generate a desired target molecule from two separate regions involving intron /exon boundaries. For these situations, the generation of full-length complementary DNAs from two partial genomic clones becomes necessary for the family of low abundance genes.

Results

The first approach we used for the isolation of full-length cDNA from two known genomic clones of Hox genes was based on fusion PCR. Here we describe a simple and efficient method …

Review Of City Of Plagues: Disease, Poverty And Deviance In San Francisco, John Stephen Brantley

Faculty & Staff Research & Creative Activity

No abstract provided.

Department Of Veterinary And Biomedical Sciences: 2000 Annual Report

School of Veterinary and Biomedical Sciences: Information and History

Foreword, 2000 John A . Schmitz. Professor and Department Head
Veterinary and Biomedical Sciences Personnel
Faculty Profiles
Teaching program
Research program
Extension Program
Nebraska Veterinary and Diagnostic Laboratory Systems
Grants and Contracts Funded or Active in 2000
Patents by VBMS Faculty in 2000
Publications by VBMS Faculty in 2000
Presentations by VBMS Faculty in 2000
Articles Regarding the Department in 2000
Selected Committees, Editorial and Other Appointments of VBMS Faculty
Departmental Budget Summaries
Nebraska Agricultural Statistics 1999

‘Gene Shaving’ As A Method For Identifying Distinct Sets Of Genes With Similar Expression Patterns, Trevor Hastie, Robert Tibshirani, Michael B. Eisen, Ash Alizadeh, Ronald Levy, Louis Staudt, Wing C. Chan, David Botstein, Patrick Brown

United States Public Health Resources

Background: Large gene expression studies, such as those conducted using DNA arrays, often provide millions of different pieces of data. To address the problem of analyzing such data, we describe a statistical method, which we have called ‘gene shaving’. The method identifies subsets of genes with coherent expression patterns and large variation across conditions. Gene shaving differs from hierarchical clustering and other widely used methods for analyzing gene expression studies in that genes may belong to more than one cluster, and the clustering may be supervised by an outcome measure. The technique can be ‘unsupervised’, that is, the genes and …

Interleukin-1 Polymorphisms Associated With Increased Risk Of Gastric Cancer, Emad M. El-Omar, Mary Carrington, Wong-Ho Chow, Kenneth E. L. Mccoll, Jay H. Bream, Howard A. Young, Jesus Herrera, Jolanta Lissowska, Chiu-Chin Yuan, Nathaniel Rothman, George Lanyon, Maureen Martin, Joseph F. Fraumeni Jr., Charles S. Rabkin

United States Public Health Resources

Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease¹. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and anatomical distribution of gastritis induced by H. pylori. Thus, individuals with gastritis predominantly localized to the antrum retain normal (or even high) acid secretion², whereas individuals with extensive corpus gastritis develop hypochlorhydria and gastric atrophy³, which are presumptive precursors of gastric cancer4. Here we report that interleukin-1 gene cluster polymorphisms suspected of enhancing production of interleukin-1-beta …

U.S. Obstetric Procedures, 1998, Sally C. Curtin, T. J. Mathews

United States Public Health Resources

According to the latest birth data from the National Center for Health Statistics, the use of electronic fetal monitoring, ultrasound, stimulation of labor, and induction of labor continued to rise in 1998 to unprecedented levels (1). At the same time, the total cesarean rate, which had fallen each year from 1989 to 1996, rose for the second consecutive year while the primary cesarean rate (rate per 100 births to women with no previous cesarean) rose for the first time during the 1989–1998 period. After increasing by 50 percent between 1989 and 1996, the rate of vaginal birth after previous cesarean …

The Annual Report To The Nation On The Status Of Cancer, 1973– 1997, With A Special Section On Colorectal Cancer, Lynn A. G. Ries, Phyllis A. Wingo, Daniel S. Miller, Holly L. Howe, Hannah K. Weir, Harry M. Rosenberg, Sally W. Vernon, Kathleen Cronin, Brenda K. Edwards

United States Public Health Resources

BACKGROUND. This annual report to the nation addresses progress in cancer prevention and control in the U.S. with a special section on colorectal cancer. This report is the joint effort of the American Cancer Society, the National Cancer Institute (NCI), the North American Association of Central Cancer Registries (NAACCR), and the Centers for Disease Control and Prevention (CDC), including the National Center for Health Statistics (NCHS).

METHODS. Age-adjusted rates were based on cancer incidence data from the NCI and NAACCR and underlying cause of death as compiled by NCHS. Joinpoint analysis was based on NCI Surveillance, Epidemiology, and …

Hyperphosphorylation Of The Asialoglycoprotein Receptor In Isolated Rat Hepatocytes Following Ethanol Administration, Benita L. Mcvicker, Dean J. Tuma, Carol A. Casey

United States Public Health Resources

Ethanol administration leads to altered function and impaired receptor-mediated endocytosis of the hepatocyte asialoglycoprotein receptor (ASGP-R). The purpose of the present study was to examine the effects of ethanol on the phosphorylation of the ASGP-R to determine whether this post-translational modification could contribute mechanistically to the observed ethanol-induced alterations. The methodological approach of this work involved the measurement of the phosphorylation state of the receptor obtained from isolated rat hepatocytes, using a combination of experimental designs from the biosynthetic incorporation of phosphate to the determination of steady-state phosphotyrosine levels. We report here that both short-term (1- to 2-week) and chronic …

Genetic Characterization Of H3n2 Influenza Viruses Isolated From Pigs In North America, 1977–1999: Evidence For Wholly Human And Reassortant Virus Genotypes, Alexander I. Karasin, Melissa M. Schutten, Lynn A. Cooper, Catherine B. Smith, Kanta Subbarao, Gary A. Anderson, Suzanne Carman, Christopher W. Olsen

United States Public Health Resources

Since 1998, H3N2 viruses have caused epizootics of respiratory disease in pigs throughout the major swine production regions of the U.S. These outbreaks are remarkable because swine influenza in North America had previously been caused almost exclusively by H1N1 viruses. We sequenced the full-length protein coding regions of all eight RNA segments from four H3N2 viruses that we isolated from pigs in the Midwestern U.S. between March 1998 and March 1999, as well as from H3N2 viruses recovered from a piglet in Canada in January 1997 and from a pig in Colorado in 1977. Phylogenetic analyses demonstrated that the 1977 …

Lessons Learned In Applying The U.S. Epa Proposed Cancer Guidelines To Specific Compounds, Melvin Andersen, M. Elizabeth Meek, Gary Boorman, David Brusick, Samuel Cohen, Yvonne Dragan, Clay Frederick, Jay Goodman, Gordon Hard, Ellen O'Flaherty, Denise Robinson

United States Public Health Resources

An expert panel was convened to evaluate the U.S. Environmental Protection Agency’s “Proposed Guidelines for Carcinogen Risk Assessment” through their application to data sets for chloroform (CHCl₃) and dichloroacetic acid (DCA). The panel also commented on perceived strengths and limitations encountered in applying the guidelines to these specific compounds. This latter aspect of the panel’s activities is the focus of this perspective. The panel was very enthusiastic about the evolution of these proposed guidelines, which represent a major step forward from earlier EPA guidance on cancer-risk assessment. These new guidelines provide the latitude to consider diverse scientific data …

Ham-Tmc Facts And Figures 1999-2000, Houston Academy Of Medicine-Texas Medical Center Library

Library Statistics

No abstract provided.

Use Of Gis To Evaluate Livestock-Wildlife Interactions Relative To Tuberculosis Spread On Molokai Island, Hawaii, Stephanie Bany, Jerome Freier

Michigan Bovine Tuberculosis Bibliography and Database

Historically, bovine tuberculosis has occurred and been eradicated several times on the Hawaiian island of Molokai. After the most recent depopulation of cattle, TB was again identified in an adult cow in 1997, thus continuing the investigation into why bovine tuberculosis is reoccurring on the island. The Centers for Epidemiology and Animal Health (CEAH) have implemented spatial analysis using ArcView software that, along with epidemiological investigations, attempts to identify the environmental factors responsible for maintaining this disease in natural foci. To examine the ecological aspects of tuberculosis transmission from wildlife to livestock, and to identify the foci of infection, we …

Male Circumcision And Hiv Prevention: Directions For Future Research, Johannes Van Dam, Marie Christine Anastasi

HIV and AIDS

A growing body of scientific publications suggests that male circumcision is associated with reduced risk of HIV infection in sub-Saharan Africa. Thus, male circumcision is being considered as a potential intervention in the prevention of sexually transmitted HIV infection, even though this procedure has profound cultural implications and carries the risk of complications, and its benefits are realized only many years later. This report presents the findings of a meeting of international researchers, organized by the Horizons Project to explore the programmatic and research implications of the association between male circumcision and HIV prevention. Most studies on male circumcision and …