Medicine and Health Sciences Commons^™

October - December 2003 Quarterly Report, Unm Health Sciences Library And Informatics Center

Native Health Database project records

NHDs quarterly report.

A Qualitative Review Of The Native American Caregivers Support Program: The Successes, Barriers, And Training Needs, Holly A. Beard, M. Yvonne Jackson, Meg Graves, Floyd Godfrey, Clare Houseman

Ellmer School of Nursing Faculty Publications

Caregiving is accepted as a natural part of life and is recognized as an inherent responsibility within the American Indian/Alaskan Native Community. A qualitative analysis was conducted employing constant comparative method to explain the current status of the Native American Caregiver Support Program (NACSP) funded by Title VI-C grants. The NACSP (Title VI-C) of the Older Americans Act (OAA) is administered by the Department of Health and Human Services (DHHS), Administration on Aging (AoA). The NACSP allows each tribal organization to develop a program to deliver supportive services that are tailored to the needs of their caregiver's while providing five …

Needed: Urologic Nursing Mentors For New Grads, Karen A. Karlowicz

Ellmer School of Nursing Faculty Publications

Presents the accomplishment felt after a completion of intense course of study. Inundation of nursing graduates; Assessment of nursing education programs; Tips to develop the role as urologic nurse.

Communication Apprehension And Interpersonal Skills In Physical Therapy Students : A Comparative Study Of Problem-Based Learning And Traditional Curricula, Beverly D. Fein

All PTHMS Faculty Publications

Physical Therapy education has been challenged to prepare students to meet the increasing demands upon and changing needs of physical therapy practice in the evolving health delivery system. Today's practitioner needs strong interpersonal and collaborative skills for effective communication with patients, families, third party payers, community and other members of the health care team. The characteristics of problem-based learning (PBL) curricula appeared to offer greater potential for students to develop communication skills as compared to traditional curricula. Therefore, this study used available measures of communication apprehension and clinical performance of communication related behaviors to compare students educated in PBL curricula …

Morphological And Functional Characteristics Of Skeletal Muscle Fibers From Hormone-Replaced And Nonreplaced Postmenopausal Women, Todd Shoepe

Health and Human Sciences Faculty Works

We tested the hypothesis that cross-bridge mechanisms of contraction differed in early postmenopausal women who did or did not receive hormone replacement therapy (HRT). Vastus lateralis biopsies were obtained from 17 postmenopausal women (49-57 years old), 8 of whom were on HRT for the previous 24 ± 5 months and 9 of whom were never on HRT. Electrophoresis and enzyme histochemistry revealed that fiber myosin heavy chain (MHC) isoform distribution, the cross-sectional area (CSA) of slow and fast fibers, and the relative CSA occupied by each, were similar for HRT and non-HRT groups. Single permeabilized fibers containing type IIa MHC …

Increased Receptor-Mediated Gene Delivery To The Liver By Protamine-Enhanced-Asialofetuin-Lipoplexes, M. A. Arangoa, Nejat Düzgüneş, C. Tros De Ilarduya

All Dugoni School of Dentistry Faculty Articles

A novel lipidic vector composed of DOTAP/Chol liposomes, asialofetuin (AF), protamine sulfate and DNA has been developed. The resulting protamine-AF-lipoplexes improved significantly the levels of gene expression in cultured cells and in the liver upon i.v. administration. Lipoplexes containing the optimal amount of AF (1 μg/μg DNA) showed a 16-fold higher transfection activity in HepG2 cells than non-targeted (plain) complexes. The uptake by cells having asialoglycoprotein receptors (ASGPr) on their plasma membrane was decreased by the addition of free AF, indicating that AF-lipoplexes were taken up specifically by cells via ASGPr-mediated endocytosis. Results from transfections performed in cells defective in …

Osmosensitive Taurine Release: Does Taurine Share The Same Efflux Pathway With Chloride And Other Amino Acid Osmolytes?, Rodrigo Franco

School of Veterinary and Biomedical Sciences: Faculty Publications

Swelling subsequent to hyposmotic conditions activates a process of volume regulation present in most cell types. This volume adjustment is accomplished by osmolyte translocation toward the extracellular space to reach a new osmotic equilibrium. Molecules involved in this homeostatic mechanism have been broadly classified into two categories: organic and inorganic osmolytes. Inorganic osmolytes comprise mainly the intracellular ions K⁺ and Cl^–. Cell swelling–induced activation of separate K⁺ and Cl^– channels has been described in most preparations. Organic osmolytes are grouped in three categories: amino acids, polyalcohols, and methylamines. These osmolytes, particularly taurine, are present in …

Role Of Activator Protein-1 In The Down-Regulation Of The Human Cyp2j2 Gene In Hypoxia, Nicole Y. Marden, Eva Fiala-Beer, Shi-Hua Xiang, Michael Murray

School of Veterinary and Biomedical Sciences: Faculty Publications

The cytochrome P450 (CYP) 2J2 arachidonic acid epoxygenase gene was down-regulated at a pre-translational level in human hepatoma-derived HepG2 cells incubated in a hypoxic environment; under these conditions, the expression of c-Jun and c-Fos mRNA and protein was increased. The 5′-upstream region of the CYP2J2 gene was isolated by amplification of a 2341 bp fragment and putative regulatory elements that resembled activator protein-1 (AP-1)-like sequences were identified. From transient transfection analysis, c-Jun was found to strongly activate a CYP2J2–luciferase reporter construct, but co-transfection with plasmids encoding c-Fos or c-Fos-related antigens, Fra-1 and -2, abrogated reporter activity. Using a series …

Comparison Of Implicit And Explicit Learning Processes In A Probabilistic Task, Thomas D. Green, John H. Flowers

Department of Psychology: Faculty Publications

This experiment compared the performance with explicit (rule-application and rule-discovery) and implicit (nonrule-instructed) learning approaches on the performance of a probabilistic video game task requiring fine motor control. The task required visual tracking of a small ball of light and “catching” it by means of joystick manipulation. A general pattern of improvement with practice occurred for all conditions. All conditions showed use of predictive relations among stimulus events. However, task performance of the rule-application and rule-discovery conditions were inferior to the nonrule-instructed implicit condition, particularly during the early phases of rule acquisition and application. This pattern strongly suggests substantial performance …

Geographic Variation In Song Of The Bright-Rumped Attila (Tyrannidae: Attila Spadiceus): Implications For Species Status, Daniel Leger, D. James Mountjoy

Department of Psychology: Faculty Publications

Bright-rumped Attilas (Attila spadiceus) have two song forms, one sung primarily at dawn, the other primarily during the rest of the day. Both songs consist of a main phrase and an optional terminal phrase. Our recordings of dawn and day songs in Costa Rica were very similar to those made elsewhere in Central America. However, Central American dawn songs were significantly different than dawn songs from South America, both in terms of quantitative features (temporal and frequency variables) and qualitative characteristics (note shape). Day songs from Central and South America were similar. Song differences suggest that the Bright-rumped …

Consumption Of Omega-3 Fatty Acid-Enriched Eggs And Serum Lipids In Humans, Ji-Young Lee, Nancy M. Lewis, Sheila Scheideler, Timothy P. Carr

Department of Nutrition and Health Sciences: Faculty Publications

This study examined the effectiveness of consuming omega-3 fatty acid-enriched eggs (Omega Eggs) in increasing total diclary omega-3 fatty acids. Also examined was the impact of Omega Egg consumption on serum lipids. Sixteen hypercholesterolemic men and women with baseline serum total cholesterol concentrations of 5.17-7.76 mmol/L (200-300 mg/dL) followed the National Cholesterol Education Program Step I diet guidelines under the following conditions: (a) Step 1 diet without eggs, (b) Step I diet plus 12 regular eggs per week, and (c) Step I diet plus 12 Omega Eggs per week. The study design was a repeated 3 x 3 Latin square …

Experimental Mycobacteriosis In Striped Bass Morone Saxatilis, D. T. Gauthier, M. W. Rhodes, W. K. Vogelbein, H. Kator, C. A. Ottinger

Biological Sciences Faculty Publications

Striped bass Morone saxatilis were infected intraperitoneally with approximately 10⁵ Mycobacterium marinum, M. shottsii sp. nov., or M. gordonae. Infected fish were maintained in a flow-through freshwater system at 18 to 21°C, and were examined histologically and bacteriologically at 2, 4, 6, 8, 17, 26, 36 and 45 wk post-infection (p.i.). M. marinum caused acute peritonitis, followed by extensive granuloma development in the mesenteries, spleen and anterior kidney. Granulomas in these tissues underwent a temporal progression of distinct morphological stages, culminating in well-circumscribed lesions surrounded by normal or healing tissue. Mycobacteria were cultured in high numbers from …

Enhancement Of Disease And Pathology By Synergy Of Trichuris Suis And Campylobacter Jejuni In The Colon Of Immunologically Naive Swine, Linda S. Mansfield, David T. Gauthier, Sheila R. Abner, Kathryn M. Jones, Stacey R. Wilder, Joseph F. Urban

Biological Sciences Faculty Publications

Campylobacter jejuni, a leading cause of bacterial gastroenteritis, has different age distribution and disease expression in developing and developed countries, which may be due to the endemnicity of infection and the age of acquisition of immunity. Differences in disease expression are not solely dependent on the C jejuni strain or virulence attributes. Another modulating factor in developing countries may be endemic nematode infections such as Trichuris, which drive type 2 cytokine responses and down-regulate type I immune responses. In this study, three-day-old germfree pigs given dual infections with Trichuris suis and C jejuni had more frequent, more severe …

Évaluation Des Indices De Contrainte Thermique En Mines Profondes, Pierre C. Dessureault, Mathieu Doucet

Rapports de recherche scientifique

L’Association Minière du Québec a logé une demande à l’effet d’utiliser le Air Cooling Power (ACP) comme indice de contrainte thermique dans les mines souterraines. Cet indice est en fait une adaptation de l’approche analytique basée sur le calcul du bilan thermique entre l’homme et son environnement. L’objectif premier de cette étude est de déterminer si cette approche rationnelle est au moins équivalente ou encore plus appropriée aux conditions de travail en mine profonde que l’application de l’indice WBGT. Elle doit aussi vérifier que le niveau d’astreinte thermique des travailleurs soit en deçà des limites généralement acceptées sous l’un ou …

Quantification De La Variabilité Biologique À L'Aide De La Modélisation : Élaboration D'Un Guide De Stratégie Pour La Surveillance Biologique De L'Exposition, Ginette Truchon, Robert Tardif, Pierre-Olivier Droz, Ginette Charest-Tardif, Guillaume Pierrehumbert, Daniel Drolet

Rapports de recherche scientifique

Certaines caractéristiques liées à l’individu, aux contaminants, à la tâche ou au milieu de travail peuvent engendrer des variations importantes dans les niveaux biologiques retrouvés chez un individu pour un indicateur donné. La présente étude vise à documenter ces facteurs de modification par le biais d’une revue de la littérature scientifique (approche qualitative) et de procéder à des études de modélisation afin de quantifier l’impact exercé par certains facteurs sur la valeur des indicateurs biologiques d’exposition documentés dans le Guide de surveillance biologique – Prélèvement et interprétation des résultats de l’IRSST.

Le facteur le plus important pour les solvants organiques …

Cancer Mortality Among American Indians And Alaska Natives: Regional Differences, 1994-1998, D.K. Espey, R.E. Paisano, N. Cobb

Native Health Database Full Text

This monograph delineates cancer mortality rates among American Indians and Alaska Native within the different regions served by the Indian Health Service (IHS). The table and charts depict broader geographic regions than in previous IHS cancer mortality monographs. The estimated IHS service population for each region and the cancer mortality rates from 1994 to 1998 are presented. Comparisons are made to the general U.S. population for the same time period. The intention of this publication is to provide detailed information about thew impact of cancer among Native American peoples, with a focus on the regional variability of cancer incidence for …

Final Report On Evaluation Of Indian Health Service Funded Community Alcohol Service Programs., Indian Health Service

Native Health Database Full Text

The IHS Strategic Plan is the product of a diverse workgroup with expertise in various facets of healthcare from clinical care to facilities construction. The IHS Strategic plan entails four goals: Build Healthy Communities, Achieve Parity in Access by 2010, Provide Compassionate Quality Health Care, and Embrace Innovation. Each of these goals are outlined alongside their respective strategies for accomplishment.

Family Connectedness And Sexual Risk-Taking Among Urban Youth Attending Alternative High Schools, Christine M Markham, Susan R Tortolero, S Liliana Escobar-Chaves, Guy S Parcel, Ronald Harrist, Robert C Addy

Faculty, Staff and Student Publications

CONTEXT: Youth in alternative high schools engage in risky sexual behavior at higher rates than do their peers in regular schools, placing themselves at an increased risk of sexually transmitted disease and unintended pregnancy. Family connectedness is associated with reduced adolescent sexual risk-taking, although this association has not been tested among alternative school youth.

METHODS: A sample of 976 urban, predominantly minority alternative high school students in Houston, Texas, were surveyed in 2000-2002. Survey data were analyzed using logistic regression to determine whether family connectedness is related to sexual risk-taking.

RESULTS: Overall, 68% of students reported ever having had sex. …

Saru, A Sara Homolog, Is Repressed By Sart And Regulates Virulence Genes In Staphylococcus Aureus, Adhar C. Manna, Ambrose L. Cheung

Dartmouth Scholarship

In searching the Staphylococcus aureus genome, we previously identified sarT, a homolog of sarA, which encodes a repressor for alpha-hemolysin synthesis. Adjacent but transcribed divergently to sarT is sarU, which encodes a 247-residue polypeptide, almost twice the length of SarA. Sequence alignment disclosed that SarU, like SarS, which is another SarA homolog, could be envisioned as a molecule with two halves, with each half being homologous to SarA. SarU, as a member of the SarA family proteins, disclosed conservation of basic residues within the helix-turn-helix motif and within the beta hairpin loop, two putative DNA binding domains within this protein …

State Mandated Prenatal Human Immunodeficiency Virus Screening At A Large Community Hospital, William Cusick, Julie G. Stewart, Michael Parry, Gavin Mcleod, Gerald Rakos, Chris Sullivan, John Rodis

Nursing Faculty Publications

Purpose: To describe the initial experience of state mandated prenatal HIV screening at a large community hospital.
Methods: HIV screening was provided to all pregnant women as of October 1, 1999. All HIV-positive women identified received aggressive antiretroviral therapy to reduce the likelihood for vertical transmission. Neonates were screened for HIV at zero, six, and 12 months of age.
Results: Seven pregnant women (0.3%) and two additional family members tested positive for HIV. All seven infants born to the identified HIV-positive women have tested negative for infection. We estimated that six of nine cases of HIV infection identified would have …

A Comparison Of Human Energy Fields Among Children, Youth, Adults, & Dahn Masters, Geoffrey K. Leigh, Karen A. Polonko, Catherine D. Leigh

Sociology & Criminal Justice Faculty Publications

While concepts and investigations of human energy fields have been developed for centuries, there has been little systematic work comparing the fields of children, adolescents, and adults. In addition, general fields have had little comparison between average adults and those participating in an intense practice that may affect the field. Using the GDV machine, this research compared small groups of children, adolescents, average adults, and Dahn Hak Masters on measures of 20 basic aspects of the human energy fields, including the seven chakras. Differences were found in seven of the 13 field parameters as well as all seven measures of …

Perfecting The Match: The Visual Economy Of Egg Donation, Katherine M. Boulay

Doctoral

This thesis is a response to the absence of discussion in feminist and cultural studies of Assisted Reproductive Technology’s (ART) increasing utilisation of visuality and technology as complementary legitimating discourses. While critiques of the epistemologies and practices undergirding ART point to the fact that imaging technologies are used to reveal knowledge held in bodies, lacking in current theoretical work on ART, however, is an ethnographic engagement with how visual technologies actually produce the internal and externalscapes of these bodies, and knowledges about them. Mapping selective visual knowledges and technologies constitutive of the ART egg donation, the thesis engages with disparate …

Identification Of A Minimal Promoter Sequence For The Human N-Acetyltransferase Type I Gene That Binds Ap-1 (Activator Protein 1) And Yy-1 (Yin And Yang 1), Neville J. Butcher, Ajanthy Arulpragasam, Catherine Pope, Rodney F. Minchin

Medical Papers and Journal Articles

Human N-acetyltransferase Type I (NAT1) catalyses the acetylation of many aromatic amine and hydrazine compounds and it has been implicated in the catabolism of folic acid. The enzyme is widely expressed in the body, although there are considerable differences in the level of activity between tissues. A search of the mRNA databases revealed the presence of several NAT1 transcripts in human tissue that appear to be derived from different promoters. Because little is known about NAT1 gene regulation, the present study was undertaken to characterize one of the putative promoter sequences of the NAT1 gene located just upstream of …

Prostate Cancer: Some Clinical And Scientific Dilemmas., Paul D. Abel, El-Nasir Lalani

Department of Pathology and Laboratory Medicine

No abstract provided.

Fludarabine Induced Immune Thrombocytopenia In A Patient With Cd5 Positive B Cell Chronic Lymphocytic Leukemia, M. Usman, Salman Adil, R. Sajid, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Fludarabine is a purine nucleoside analogue, which inhibits DNA synthesis by inhibiting DNA polymerase and ribonucleoside reductase.1 It affects both dividing and non- dividing cells.2 Fludarabine possesses proven efficacy in the treatment of a variety of indolent B cell lymphoproliferative disorders including chronic lymphocytic leukemia3, low-grade non-Hodgkin's lymphoma4 and Waldenstrom macroglobulinemia.5 It is also a part of conditioning regimes in non-myeloablative bone marrow transplantation.6 The common side effects include myelosuppression, immunosuppression, and neurologic toxicity.7 The rare side effects are immune mediated hemolytic anemia8 and thrombocytopenia.9 Here we describe a case of a middle-aged lady who was diagnosed as B cell …

Cyclosporin Induced Fatal Rhabdomyolysis In A Young Patient With Acquired Aplastic Anemia: A Case Report, M. Usman, S. N. Adil, G. N. Kakepoto, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Cyclosporin is used as an immunosuppressive agent in the management of a variety of autoimmune disorders1 and in patients of organ transplant to suppress host immunity and prevent rejection.2 It is now well established that acquired aplastic anemia is secondary to immune mediated destruction of stem cells in the bone marrow3 and hence Cyclosporin is used as a first line immunosuppressive drug alone or in combination with anti lymphocyte globulin in the management of aplastic anemia.1 Rhabdomyolysis is a rare side effect of Cyclosporin.4 Here we describe a case of fatal rhabdomyolysis in a young patient who received cyclosporin for …

Chromosomal Abnormalities As A Cause Of Recurrent Abortions: A Hospital Experience, M. Azim, A.H. Khan, Z.L. Khilji, J.A. Pal, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Objective: To analyze the chromosomal abnormalities in couples with history of recurrent abortions.
Design: Retrospective study.
Setting: Cytogenetic section, Department of Pathology at the Aga Khan University Hospital. Karachi, Pakistan. Patients: Three hundred couples with history of recurrent abortions. Main outcome measure: Structural chromosomal abnormalities in carrier couples.
Results: G-banded chromosomes were analyzed from both partners of 300 couples who had had two or more spontaneous abortions. Sixteen (5.3%) couples showed a chromosomal aberration in one of the partners. Seven translocations, 5 inversions, 2 deletions and 2 sex chromosomal abnormalities were identified. There was an increase in …

An Educational Curriculum For Teaching Life Care Planning, Rodney N. Isom, Irmo Marini

School of Rehabilitation Services & Counseling Faculty Publications

Life care planning is a service offered by some rehabilitation consultants. However, few graduate rehabilitation counseling programs offer a course in life care planning. This article outlines the proposed content for a graduate level course in life care planning. The curriculum outlines the teaching content, resources, and teaching recommendations for 15 weeks of instruction. Relevant resources are included. “A Life Care Plan is a dynamic document based upon published standards of practice, comprehensive assessment, data analysis and research, which provides an organized concise plan for current and future needs with associated costs, for individuals who have experienced catastrophic injury or …

Life Care Planning: Rehabilitation Education Curricula And Faculty Needs, Rodney N. Isom, Irmo Marini, Chuck Reid

School of Rehabilitation Services & Counseling Faculty Publications

A survey of programs providing vocational rehabilitation counselor education demonstrated little available curriculum regarding life care planning and expert testimony. This article reports on the results of a survey study and suggests that curriculum specific to life care planning and case management be added to university rehabilitation counselor training programs.

Implementing A Fundamental Movement Skill Program In An Early Childhood Setting: The Teachers’ Perspectives, Marie Martin, Beth P. Hands

Health Sciences Papers and Journal Articles

The place of explicit movement skill development programs in early childhood settings is contentious. However given the growing understanding that movement competence is important for maintaining an active and healthy lifestyle (Hands, Parker, & Larkin, 2001), well planned and effective programs specifically designed for young children are important.

In this paper, the influence of a new teaching resource designed to support teachers in implementing a fundamental movement skill program is presented using a case study approach. The case studies were constructed with teachers working in a range of early childhood settings. The impact of the program on teachers’ level of …