Medicine and Health Sciences Commons^™

Rosenzweig's Messianic Aesthetics, Jules Simon

Selected Works Temporary Series

No abstract provided.

Precautionary Approaches For Health And The Environment: Making The Case For A Toxics Reduction Strategy At Multnomah County And City Of Portland, Stephanie Farquhar, Molly Chidsey, Neha Patel

Community Health Faculty Publications and Presentations

This report summarizes an overview of the problem, local concerns, model policies, and best practices for toxic pollution prevention and provides recommendations for next steps to protect human health and the local environment in Portland and Multnomah County. This report accompanies the Multnomah County and City of Portland resolutions to "Recognize National Pollution Prevention Week and develop a Toxics Reduction Strategy jointly with City of Portland / Multnomah County using the Precautionary Principle."

Sars Surveillance During Emergency Public Health Response, United States, March-July 2003, Stephanie J. Schrag, John T. Brooks, Chris Van Beneden, Umesh D. Parashar, Patricia M. Griffin, Larry J. Anderson, William J. Bellini, Robert F. Benson, Dean D. Erdman, Alexander Klimov, Thomas G. Ksiazek, Teresa C. T. Peret, Deborah F. Talkington, W. Lanier Thacker, Maria L. Tondella, Jacquelyn S. Sampson, Allen W. Hightower, Dale F. Nordenberg, Brian D. Plikaytis, Ali S. Khan, Nancy E. Rosenstein, Tracee A. Treadwell, Cynthia G. Whitney, Anthony E. Fiore, Tonji M. Durant, Joseph F. Perz, Annemarie Wasley, Daniel Feikin, Joy L. Herndon, William A. Bower, Barbara W. Klibourn, Deborah A. Levy, Victor G. Coronado, Joanna Buffington, Clare A. Dykewicz, Rima F. Khabbaz, Mary E. Chamberland

Journal Articles: Epidemiology

In response to the emergence of severe acute respiratory syndrome (SARS), the United States established national surveillance using a sensitive case definition incorporating clinical, epidemiologic, and laboratory criteria. Of 1,460 unexplained respiratory illnesses reported by state and local health departments to the Centers for Disease Control and Prevention from March 17 to July 30, 2003, a total of 398 (27%) met clinical and epidemiologic SARS case criteria. Of these, 72 (18%) were probable cases with radiographic evidence of pneumonia. Eight (2%) were laboratory-confirmed SARS-coronavirus (SARS-CoV) infections, 206 (52%) were SARS-CoV negative, and 184 (46%) had undetermined SARS-CoV status because of …

Ua61/1 Wku Nursing Class 2004, Wku Nursing

WKU Administration Documents

Members of the 2004 nursing class: Angie Atwood, Teresa Bertrand, Melanie Blunk, Amanda Brady, Aimee Brown, Sarah Bruce, Jenny Bush, Mary Bybee, Darby Carter, Shelia Catlett, Libby Cawthorn, Allison Clifton, Jennifer Combs, Vicky Compton, Abigail Cooper, Mary Croley, Whitney Cunningham, Pamela Deel, Christina Dill, Bonnie Embrey, Christy Hall-Simpson, Amy Hanes, Laura Harmon, Deanna Hart, Kim Haynes, Stacey Hiser, Gayle Hooks, Maureen Horvath, Susan Jackewicz, Alicia Jackson, Robbyn Jewell, Libby Johnson, Joyce Keel, Tracey Keen, Mary King, Casey Lanius, Karla Lee, Britanny London, Heather Luellen, Teresa Martin-Curd, Keely Miller, Colleen Mulligan, Nena Nokes, Kimberly Owens, Roxie Perry, Pam Phelps, Jessica Phillips, …

Ua61/1 Wku Nursing Class 2004, Wku Nursing

WKU Administration Documents

Members of the 2004 nursing class: Glenda Bagby, Sharon Campbell, Cynthia Campbell, Brianah Doeden, Jamie Dorris, Amy Frazier, Dawn Garrett, Marilyn Graves, Lisa Hays, Laurel Henderson, Victoria Kingery, Alice Kirby, Sherry Lovan, Heather Parsley, Lorena Steenbergen and Douglas Williams.

Review Of Educational Materials: Let’S Get Moving With Exercise And Healthy Foods And Let’S Get Moving With Healthy Snacks And Play, Bridget Schade, Carrie O'Donnell, Melanie Burns

Faculty Research & Creative Activity until 2018 (FCS)

No abstract provided.

Web Site Review: The President’S Challenge, Erin Boester, Lisa Cunningham, Melanie Burns

Faculty Research & Creative Activity until 2018 (FCS)

No abstract provided.

Educational Materials Review: Calcium: Are You Getting Enough?, Abigail Field, Christina Pruemer, Melanie Burns

Faculty Research & Creative Activity until 2018 (FCS)

No abstract provided.

Educational Materials Review: Choosing A Safe And Successful Weight-Loss Program And You Can Control Your Weight As You Quit Smoking., Lee Ann Price, Elizabeth Stanberry, Melanie Burns

Faculty Research & Creative Activity until 2018 (FCS)

No abstract provided.

Review Of Educational Materials: Let’S Get Moving With Exercise And Healthy Foods And Let’S Get Moving With Healthy Snacks And Play, Bridget Schade, Carrie O'Donnell, Melanie Burns

Faculty Research & Creative Activity

No abstract provided.

Educational Materials Review: Calcium: Are You Getting Enough?, Abigail Field, Christina Pruemer, Melanie Burns

Faculty Research & Creative Activity

No abstract provided.

Medical Training Using Simulation: Toward Fewer Animals And Safer Patients, Jonathan Balcombe

Experimentation Collection

This paper presents the current status of computer-based simulation in medicine. Recent technological advances have enabled this field to emerge from esoteric explorations in academic laboratories to commercially available simulators designed to train users to perform medical procedures from start to finish. Today, more than a dozen companies are producing virtual reality simulators and interactive manikins for training in endoscopy, laparoscopy, anaesthesia, trauma management, angiography, and needle insertion. For many of these procedures, thousands of animals are still being used in training. Yet simulation has many advantages that can transcend scientific, ethical, economic and logistical problems that arise when using …

Levels Of Citation Of Nonhuman Animal Studies Conducted At A Canadian Research Hospital, Anne Innis Dagg, Troy K. Seidle

Experimentation Collection

The publication of scientific articles that receive few or no citations raises questions of the appropriate use of resources as well as ethics. In the case of animal research, the ethics issue extends beyond human patients to nonhuman animals, as the research subjects them to pain and, typically, to death. This study is a citation analysis of animal research conducted at Toronto's Hospital for Sick Children (HSC). Of the 594 publications (1990 to 1995) on animal research by affiliates of HSC, 29% received Iower than 10 citations in a 10-year period. We compare the research history of 13 "best" and …

Animals And Alternatives: Societal Expectations And Scientific Need, Alan M. Goldberg

Experimentation Collection

As Russell and Burch suggested more than 40 years ago, the most humane science is the best science. The path ahead is clear: pain and distress must be eliminated in animal experiments or reduced to an absolute minimum, and, as scientists, we must use the most humane approaches in our research. To accomplish the best science, we must train those who come after us in the principles and practice of humane science.

Trials, Tribulations, And Trends In Tumor Modeling In Mice, Joann C. L. Schuh

Toxicology and Animal Models in Research Collection

Selection of mouse models of cancer is often based simply on availability of a mouse strain and a known compatible tumor. Frequently this results in use of tumor models long on history but short on homology and quality control. Other factors including genetics, sex, immunological status, method and site of tumor implantation, technical competence, biological activity of the tumor, protocol sequence and timing, and selection of endpoints interact to produce outcomes in tumor models. Common reliance on survival and tumor burden data in a single mouse model often skews expectations towards high remission and cure rates; a finding seldom duplicated …

Trials, Tribulations, And Trends In Tumor Modeling In Mice, Joann C. L. Schuh

Biomedicine and Animal Models in Research Collection

Selection of mouse models of cancer is often based simply on availability of a mouse strain and a known compatible tumor. Frequently this results in use of tumor models long on history but short on homology and quality control. Other factors including genetics, sex, immunological status, method and site of tumor implantation, technical competence, biological activity of the tumor, protocol sequence and timing, and selection of endpoints interact to produce outcomes in tumor models. Common reliance on survival and tumor burden data in a single mouse model often skews expectations towards high remission and cure rates; a finding seldom duplicated …

Surprises In Caregiving, Charles D. Dolph

Alumni Publications

No abstract provided.

A Processed Pseudogene Contributes To Apparent Mule Deer Prion Gene Heterogeneity, Kelly A. Brayton, Katherine I. O'Rourke, Amy K. Lyda, Michael W. Miller, Donald P. Knowles Jr.

Zoonotics and Wildlife Disease: Publications

Pathogenesis and transmission of the prion disorders (transmissible spongiform encephalopathies, TSEs) are mediated by a modified isoform of the prion protein (PrP). Prion protein gene (PRNP) alleles associated with relative susceptibility to TSE have been identified in sheep, humans and possibly elk. Comparable data have not been derived for mule deer, a species susceptible to the TSE chronic wasting disease (CWD). Initial analysis of the open reading frame (ORF) in exon 3 of the mule deer PRNP gene revealed polymorphisms in all 145 samples analyzed, with 10 potential polymorphic sites. Because 144/145 (99.3%) of the samples were heterozygous …

Resistance To Scrapie In Prp Arr/Arq Heterozygous Sheep Is Not Caused By Preferential Allelic Use, P. A. Caplazi, Katherine I. O'Rourke, T. V. Baszler

Zoonotics and Wildlife Disease: Publications

Scrapie is a prion disease in sheep that, similar to Kuru or variant Creutzfeldt-Jakob disease (vCJD), requires both prion exposure and a genetic susceptibility. Susceptibility is defined by amino acid polymorphisms in the single copy prion protein (PrP) gene, Prnp. Specifically, in sheep homozygous for A at position 136 and R at position 154, susceptibility is defined by R or Q at position 171. The genotype ARQ/ARQ confers susceptibility, whereas (apart from a few reported exceptions) genotypes ARR/ARQ and ARR/ARR confer resistance. Similarly, a M/V polymorphism at Prnp codon 129 determines susceptibility to vCJD and Kuru,4 with partial resistance conferred …

Polymorphisms In The Prion Precursor Functional Gene But Not The Pseudogene Are Associated With Susceptibility To Chronic Wasting Disease In White-Tailed Deer, Katherine I. O'Rourke, Terry R. Spraker, Linda K. Hamburg, Thomas E. Besser, Kelly A. Brayton, Donald P. Knowles

Zoonotics and Wildlife Disease: Publications

Chronic wasting disease (CWD) status and PrP genotypes were determined for a group of 133 wild white-tailed deer in a 780 acre enclosure in western Nebraska, USA. Approximately half of the deer tested showed evidence of PrP^d in the brainstem or lymphoid tissues. Four PRNP alleles encoding amino acid substitutions were identified, with substitutions at residues 95 (Q→H), 96 (G→S) or 116 (A→G), each with serine (S) at residue 138. In addition, a processed pseudogene with two alleles encoding five or six copies of the octapeptide repeat was identified in 26% of the deer. Both alleles encoded asparagine (N) …

Transmission Of Transmissible Mink Encephalopathy To Raccoons (Procyon Lotor) By Intracerebral Inoculation, Amir N. Hamir, Janice M. Miller, Katherine I. O'Rourke, Jason C. Bartz, Mick J. Stack, Melanie J. Chaplin

Zoonotics and Wildlife Disease: Publications

To determine the transmissibility of transmissible mink encephalopathy (TME) agent to raccoons and to provide information about clinical course, lesions, and suitability of currently used diagnostic procedures for detection of transmissible spongiform encephalopathies (TSEs) in raccoons, 4 raccoon kits were inoculated intracerebrally with a brain suspension from mink experimentally infected with TME. One uninoculated raccoon kit served as a control. All 4 animals in the TME-inoculated group showed clinical signs of neurologic disorder and were euthanized between 21 and 23 weeks postinoculation (PI). Necropsy examinations revealed no gross lesions. Spongiform encephalopathy was observed by light microscopy, and the presence of …

Variable Patterns Of Distribution Of Prpcwd In The Obex And Cranial Lymphoid Tissues Of Rocky Mountain Elk (Cervus Elaphus Nelsoni) With Subclinical Chronic Wasting Disease, T. R. Spraker, A. Balachandran, D. Zhuang, Katherine I. O'Rourke

Zoonotics and Wildlife Disease: Publications

Sections of medulla oblongata. taken at the level of the obex, palatine tonsil and medial retropharyngeal lymph node from 10,269 captive Rocky Mountain elk (Cervus elaphus nelsoni), were examined by immunohistochemical staining with monoclonal antibody for the prion protein associated with the transmissible spongiform encephalopathy of cervids, chronic wasting disease (PrP^CWD). The protein was detected in 226 of them. On the basis of the anatomical location of the deposits in the brainstem of 183 elk, four distinct patterns of distribution of PrP^CWD within the parasympathetic region of the dorsal motor nucleus of the vagus nerve …

Caregiver Education And Service Utilization In African American Families Dealing With Dementia, Constance L. Coogle

Virginia Center on Aging Publications

For more than a decade attention has been focused on Alzheimer’s family caregivers in African American communities. The Fourth Report of the Advisory Panel on Alzheimer’s Disease to the U. S. Congress and the U.S. Department of Health and Human Services calls for “…public education and outreach efforts specifically targeted to ethnic elders and their families and communities through the development and dissemination of culturally relevant materials emphasizing both the established facts about [Alzheimer’s Disease and Related Disorders] and the efficacy of seeking treatment.” (Advisory Panel on Alzheimer’s Disease, 1993, p. 50). While federal financing and state initiatives have addressed …

Teenagers Who Plan Parenthood, Julie A. Quinlivan

Medical Conference Papers

It is clear that a variable number of teenage mothers have, to some extent, planned parenthood. From an evolutionary perspective, it could be argued that teenage childbearing may in fact be a positive adaptive mechanism for humans raised in a hostile environment. Life history theory suggests that in risky and uncertain environments the optimal reproductive strategy is to reproduce early in order to maximise the probability of leaving any descendents at all. If some teenagers are planning or hoping for pregnancy, it is possible that some positive behavioural changes may be observed. This has proven to be the case with …

Australian Children Of Alcoholic Female Twins, Wendy S. Slutske

Posters

No abstract provided.

Neurologically Plausible Distinctions In Cognition Relevant To Drug Use Etiology And Prevention, Alan W. Stacy, Susan L. Ames, Barbara J. Knowlton

CGU Faculty Publications and Research

This article outlines several distinctions in cognition and related topics in emotion that receive support from work in cognitive neuroscience and have important implications for prevention: implicit cognition, working memory, nonverbal memory, and neurobiological systems of habit. These distinctions have not been widely acknowledged or applied in drug use prevention research, despite their neural plausibility and the availability of methods to make this link. The authors briefly review the basis for the distinctions and indicate general implications and assessment possibilities for prevention researchers conducting large-scale field trials. Subsequently, the article outlines a connectionist framework for specific applications in prevention interventions. …

A Transdisciplinary Focus On Drug Abuse Prevention: An Introduction, Steve Sussman, Alan W. Stacy, C. Anderson Johnson, Mary Ann Pentz, Elizabeth Robertson

CGU Faculty Publications and Research

This article introduces the scope of the Special Issue. A variety of scientific disciplines are brought together to establish theoretical integration of the arenas of drug use, misuse, “abuse,” and drug misuse prevention. Transdisciplinary scientific collaboration (TDSC) is utilized as a process of integration. Introductory comments regarding the strengths and limitations of TDSC are presented. Then, the relevance of genetics to substance misuse and substance misuse prevention is presented. Next, the relevance of cognition for prevention is discussed. Specifically, neurologically plausible distinctions in cognition and implicit cognition and their relevance for prevention are discussed. At a relatively molar social-level of …

The Effectiveness Of An Interactive Multimedia Learning Tool On Nursing Students' Math Knowledge And Self-Efficacy, Margaret M. Hansen Edd, Msn, Rn

Nursing and Health Professions Faculty Research and Publications

The use of online learning tutorials to provide instruction in schools of nursing is growing in popularity; however, the outcomes associated with this method of instruction are not well documented. The focus of this experimental study, conducted at 2 universities in northern California, was to determine the effectiveness of an online interactive multimedia-learning tool versus text only, text and images, and multimedia learning explanations on math achievement, math self-efficacy, and student satisfaction. Compared to students in the control groups, students in the interactive multimedia group demonstrated equal posttest and retest knowledge of math; their math self-efficacy scores were also the …

The Ehealth Behavior Management Model: A Stage-Based Approach To Behavior Change And Management, Robert J. Bensley, Nelda Mercer, John J. Brusk, Ric Underhile, Jason Rivas, Judith Anderson, Deanne Kelleher, Melissa Lupella, André C. De Jager

Human Performance and Health Education Faculty Research

Although the Internet has become an important avenue for disseminating health information, theory-driven strategies for aiding individuals in changing or managing health behaviors are lacking. The eHealth Behavior Management Model combines the Transtheoretical Model, the behavioral intent aspect of the Theory of Planned Behavior, and persuasive communication to assist individuals in negotiating the Web toward stage-specific information. It is here — at the point of stage-specific information — that behavioral intent in moving toward more active stages of change occurs.

The eHealth Behavior Management Model is applied in three demonstration projects that focus on behavior management issues: parent-child nutrition education …

Increased Ethanol Drinking By Riiâ Knockout Mice: Assessment Of Genetic Background And Testing Procedures, Jon R. Fee, Dennis R. Sparta, Mitchell J. Picker, Todd E. Thiele

Posters

No abstract provided.