Medicine and Health Sciences Commons^™

Association Study Of The Angiotensin-Converting Enzyme (Ace) Gene G2350a Dimorphism With Myocardial Infarction, M Perwaiz Iqbal, Saeed Mahmood, Naseema Mehboobali, Mohammad Ishaq, Tasnim Fatima, Saddiqa Parveen, Philippe Frossard

Department of Biological & Biomedical Sciences

The angiotensin converting enzyme (ACE) is a strong candidate gene for myocardial infarction (MI). Insertion-deletion dimorphism in intron 16 of this gene has been inconclusively found to be associated with it. Several new polymorphisms in the ACE gene have been identified and among these, a dimorphism in exon 17, ACE G2350A, has a significant effect on plasma ACE concentrations. To assess the value of genotyping the ACE G2350A dimorphism in a genetically homogeneous population, we carried out a case-control study of dimorphism G2350A for a putative association with MI among Pakistani nationals. We investigated a sample population of 370 Pakistanis, …

Research News: 2004, No. 1, University Of Mississippi. School Of Pharmacy

Research News: Grants and Publications (2000-2014)

Grants, publications, technology transfer, special announcements

On The Formulation Of Ph-Sensitive Liposomes With Long Circulation Times, Sérgio Simões, João Nuno Moreira, Cristina Fonseca, Nejat Düzgüneş, Maria C. Pedroso De Lima

All Dugoni School of Dentistry Faculty Articles

Strategies used to enhance liposome-mediated drug delivery in vivo include the enhancement of stability and circulation time in the bloodstream, targeting to specific tissues or cells, and facilitation of intracytoplasmic delivery. pH-sensitive liposomes have been developed to mediate the introduction of highly hydrophilic molecules or macromolecules into the cytoplasm. These liposomes destabilize under acidic conditions found in the endocytotic pathway, and usually contain phosphatidylethanolamine (PE) and titratable stabilizing amphiphiles. Formulations without PE have also been developed. Encapsulated compounds are thought to be transported into the cytoplasm through destabilization of or fusion with the endosome membrane. Incorporation of a low mole …

Extending The Revelation Effect To Faces: Haven’T We Met Before?, Brian H. Bornstein, Jeffrey R. Wilson

Department of Psychology: Faculty Publications

The revelation effect is an episodic memory phenomenon where participants are more likely to report that they recognized an item when it is judged after an interpolated task than when it is not. Although this effect is very robust, nearly all of the extant research has used verbal or readily verbalizable stimuli. The present two experiments examined whether a revelation effect could be produced with non-verbal stimuli such as faces. A revelation effect was found in both experiments, for both targets and lures, using faces as stimuli. The findings are integrated into the prevailing empirical frameworks for the revelation effect …

Unilateral Olfactory Thresholds In A Chemosensory Clinic Population, Beverly Cowart, Edmund Pribitkin, David Rosen, Christopher Klock, Timothy Laflam

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Poster presentation at 26th Annual Meeting of the Association of Chemoreception Sciences in Sarasota Florida, April 21-25, 2004.

INTRODUCTION

Because there is the possibility of unilateral loss of olfactory function or differential degrees of olfactory dysfunction in the two nostrils, unilateral tests of olfactory threshold sensitivity are routinely included in many chemosensory clinical test batteries to supplement bilateral tests (e.g., Cain et al., 1988; Hummel et al., 1997). Surprisingly, however, the results of unilateral testing in patients with chemosensory complaints have not been extensively reported. Thus, it is unclear how useful these additional measures are in characterizing individual patients.

A …

Ada News - 04/19/2004, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Santé Respiratoire Des Travailleurs Et Qualité De L’Air Des Tourbières Du Québec Possédant Des Systèmes De Dépoussiérage, Caroline Duchaine, Yvon Cormier, Anne Mériaux, Pascal Pageau, Madeleine Chabot, Évelyne Israël-Assayag, Nicole Goyer, Yves Cloutier, Louis Lazure

Rapports de recherche scientifique

Certains problèmes de santé reliés à la manipulation de la tourbe sont bien connus. On parle de maladie reliée à la présence de Sporothrix schenckii. La présence de Mycobacterium xenopi et M. fortuitum pourrait conduire à des infections aux reins et M.chelonae et M. gordonae pourraient être associées à l’alvéolite allergique. Si ces problèmes inhérents à la manipulation de la tourbe sont connus, aucune étude ne fait état de la microflore de l’air des tourbières et de l’exposition des travailleurs aux différents contaminants aériens comme les poussières organiques, les moisissures, bactéries, et autres produits pouvant causer des …

Animal Health Matters, David H. Zeman

Animal Health MATTERS Newsletter

Head/Director's Message [Page] 1-Equipment grant to support bioterrorism preparedness and TSE testing at the ADRDL [Page] 1- Call for Cases for the Summer Meeting Diagnostic News [Page] 2- BVD ear notch test – submission guidelines [Page] 2- Tritrichomonas pouch culture procedures at the ADRDL [Page] 2- Equine infectious anemia testing Research News [Page] 3- VSD and the Governor’s 2010 Research Initiative Extension News [Page] 3-Toxoplasma gondii and schizophrenia? [Page] 4- A survey of agents associated with neonatal diarrhea in Iowa swine including C. difficile and PRRSV [Page] 4- Avian influenza: should we be concerned about poultry in Asia?

Influenza Vaccination Coverage Among Adults With Asthma: Findings From The 2000 Behavioral Risk Factor Surveillance System, Earl S. Ford, Seymour G. Williams, David M. Mannino, Stephen C. Redd

United States Public Health Resources

The prevalence of asthma has increased substantially in the United States since 1980 (1). The primary clinical and public health strategy to reduce the burden of asthma is to prevent exacerbation of the disease, of which upper and lower respiratory tract infections are a major cause (2–5). One such infection—influenza— and its complications are potentially preventable with annual vaccination, which is a safe and effective method (6,7), including among persons with asthma (8). Because persons with asthma are at increased risk of complications from influenza, they are advised to receive annual influenza vaccinations (9), unless there are contraindications.
Little is …

Conversion Of Myoblasts To Physiologically Active Neuronal Phenotype, Yumi Watanabe, Sei Kameoka, Vidya Gopalakrishnan, Kenneth D Aldape, Zhizhong Z Pan, Frederick F Lang, Sadhan Majumder

Faculty, Staff and Student Publications

Repressor element 1 (RE1)-silencing transcription factor (REST)/neuron-restrictive silencer factor (NRSF) can repress several terminal neuronal differentiation genes by binding to a specific DNA sequence (RE1/neuron-restrictive silencer element [NRSE]) present in their regulatory regions. REST-VP16 binds to the same RE1/NRSE, but activates these REST/NRSF target genes. However, it is unclear whether REST-VP16 expression is sufficient to cause formation of functional neurons either from neural stem cells or from heterologous stem cells. Here we show that the expression of REST-VP16 in myoblasts grown under muscle differentiation conditions blocked entry into the muscle differentiation pathway, countered endogenous REST/NRSF-dependent repression, activated the REST/NRSF target …

“French Heartworm” Infection Of Dogs & Foxes In Newfoundland

Zoonotics and Wildlife Disease: Publications

French Heartworm is the common name for a parasitic disease affecting foxes, dogs, and other members of the dog family. Caused by the nematode (worm) Angiostrongylus vasorum, this disease was first thought to exist in France in the mid 1800's. It is now considered to exist generally in Europe but has not been reported in North America other than on the Island of Newfoundland, with the exception of infected animals imported from Europe but diagnosed in North America. The first case recorded in Newfoundland was in Aquaforte (Avalon Peninsula) in 1973.
When and how it might have come over …

Evaluating Markers For Selecting A Patient's Treatment, Xiao Song, Margaret S. Pepe

UW Biostatistics Working Paper Series

Selecting the best treatment for a patient's disease may be facilitated by evaluating clinical characteristics or biomarker measurements at diagnosis. We consider how to evaluate the potential of such measurements to impact on treatment selection algorithms. For example, magnetic resonance neurographic imaging is potentially useful for deciding whether a patient should be treated surgically for carpal tunnel syndrome or if he/she should receive less invasive conservative therapy. We propose a graphical display, the selection impact (SI) curve, that shows the population response rate as a function of treatment selection criteria based on the marker. The curve can be useful for …

Interview No. 1626, Judith Leonard

Combined Interviews

She goes over the various doctors that worked in El Paso; she recalls the various hospitals at the time, the building of Providence Hospital; mentions that there were few Hispanic doctors, and reveals that the medical society was closed to them except for a few from medical families; she remembers Dr. Kalikian that trained her husband; she explains why her husband’s group eventually moved their office to Murchison St, closer to Sierra Medical Center. Ms. Leonard recounts travelling for her husband’s work, describes the career and interests of her children; she goes over her family’s love of opera and talks …

Interview No. 1631, Cornelia Love Owen

Combined Interviews

Ms. Owen recounts the various physicians her father knew like Dr. Holman, his work at Hotel Du Catholic Hospital, Masonic, Southwestern General; she recalls going to Sullins College in Virginia with friends; she explains why she decided to go to Texas College of the Mines now UTEP; she gives information about her husband, sold oxygen and acetylene supplies for mining use; she describes living on Federal St. with her husband and son Dale, her son went to Southern Methodist University and later UTEP for his master’s. She provides background information on her father, born in Arkansas in 1868; she explains …

Seroprevalence Of Bartonella Infection In American Free-Ranging And Captive Pumas (Felis Concolor) And Bobcats (Lynx Rufus), Bruno B. Chomel, Yoko Kikuchi, Janice S. Martenson, Melodie E. Roelke-Parker, Chao-Chin Chang, Rickie W. Kasten, Janet E. Foley, John Laudre, Kerry Murphy, Pamela K. Swift, Vicki L. Kramer, Stephen J. O'Brien

Zoonotics and Wildlife Disease: Publications

Bartonella henselae is the main agent of cat scratch disease in humans and domestic cats are the main reservoir of this bacterium. We conducted a serosurvey to investigate the role of American wild felids as a potential reservoir of Bartonella species. A total of 479 samples (439 serum samples and 40 Nobuto strips) collected between 1984 and 1999 from pumas (Felis concolor) and 91 samples (58 serum samples and 33 Nobuto strips) collected from bobcats (Lynx rufus) in North America, Central America and South America were screened for B. henselae antibodies. The overall prevalence of B. …

Method For Identifying Regulators Of Protein-Advanced Glycation End Product (Protein-Age) Formation, Elaine L. Jacobson, Myron Jacobson, Georg T. Wondrak

Graduate Center for Nutritional Sciences Faculty Patents

The invention relates to methods for identifying compounds which affect cellular stress. In particular, the method relates to identifying compounds which inhibit protein advanced glycation end product formation, where the compounds are carbonyl scavengers which inhibit the formation. The assay involves combing the substance of interest with histone H1 and ADP-ribose, and then measuring fluorescence and protein cross linking. Various inhibitors of protein AGE glycation have been identified, using this assay.

Ada News - 04/05/2004, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Burden Of Infectious Diseases In South Asia, Anita K M Zaidi, Shally Awasthi, H Janaka Desilva

Department of Paediatrics and Child Health

No abstract provided.

Gsbs News, Spring 2003-2004, Graduate School Of Biomedical Sciences, University Of Texas Health Science Center At Houston/M.D. Anderson Cancer Center

GSBS News

No abstract provided.

Using An Automated Knowledge Agent For Reference And Customer Service, Mary Moore Phd

Faculty Research, Publications, and Presentations

Knowledge agents are software tools that sift through data to retrieve answers to questions. These agents may take many forms, including verbots, chatterbots, and intelligent agents. They have character and personality and reply to natural language inquiries. Agents “learn from their mistakes” and “grow smarter” when their programmers review failed interactions between the customer and the agent and then script correct responses.

Healthnet News V.19:No.1 Spring 2004, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.

Transplant First

Data and Test Instruments

No abstract provided.

The Influence Of Personality And Affect On Nicotine Dependence Among Male College Students, Dennis E. Mcchargue, Lee M. Cohen, Jessica Warth Cook

Department of Psychology: Faculty Publications

Many clinicians and researchers hypothesize that tobacco use disorders, regardless of the route of administration, are maintained by the ability of nicotine to regulate positive and negative mood states. The present study (N = 137) examined whether certain mood states predicted dependence on either cigarettes or smokeless tobacco and whether specific personality characteristics (e.g., extraversion, neuroticism, and psychoticism) mediated these relationships among young male college students. Results indicated that positive and negative moods predicted cigarette dependence (p values = .01) and that neuroticism partially mediated the relationship between positive affect and cigarette dependence. Exploratory analyses revealed that positive …

Ua61/6 Newsletter Issue 3, Wku Institute For Rural Health Development & Research

WKU Administration Documents

Newsletter created by and about the Institute for Rural Health Development & Research. This issue contains:

• Senator Mitch McConnell Earmarks Dollars for WKU Hispanic Initiative
• Dr. Louella Fong Directs Bilingual Program
• Give Kids a Smile Brightens Children’s Day – Dental Hygiene
• College of Health & Human Services Focuses on Gerontology Demands
• Partners Key to Successful Hispanic Health Fair & Screening Event
• Public Health Department Now Offers Worksite Health Promotion
• KEMSA Offers EMS Management Workshop – Kentucky Emergency Medical Services Academy

Chronic Wasting Disease—Prion Disease In The Wild, Steve Bunk

Zoonotics and Wildlife Disease: Publications

In 1967, mule deer in a research facility near Fort Collins, Colorado, in the United States apparently began to react badly to their captivity. At least, that was the guess of researchers working on the natural history and nutrition of the deer, which became listless and showed signs of depressed mood, hanging their heads and lowering their ears. They lost appetite and weight. Then they died—of emaciation, pneumonia, and other complications—or were euthanized. The scientists dubbed it chronic wasting disease (CWD), and for years they thought it might be caused by stress, nutritional deficiencies, or poisoning. A decade later, CWD …

Marketable Features Of The Adapted Physical Education Career In Higher Education, Jiabei Zhang

Human Performance and Health Education Faculty Research

The purpose was to investigate marketable features of the adapted physical education (APE) career in higher education. A total of 560 APE job openings (297 APE first priority and 263 APE second priority were identified from the Chronicle of Higher Education between 1975-1976 and 1997-1998. These data were analyzed by regression, chi-square, and descriptive statistics. The results indicate that the APE career is a growing employment market demanding candidates who specialize in APE to prepare in one or more other areas and encouraging candidates who specialize in other areas to minor in APE. The market shows that APE second priority …

P38 Mapk Signaling During Murine Preimplantation Development., David R Natale, Andrew J M Paliga, Frank Beier, S J A D'Souza, Andrew J Watson

Obstetrics & Gynaecology Publications

Mitogen-activated protein kinase (MAPK) pathways mediate some important cellular processes and are likely to also regulate preimplantation development. The role of p38 MAP kinase signaling during murine preimplantation development was investigated in the present study. p38 MAPK, p38-regulated or -activated kinase (PRAK; MK5), map kinase-activated protein kinase 2 (MK2), and heat shock protein 25 (hsp25) mRNAs and proteins were detected throughout preimplantation development. Two-cell stage embryos cultured in the presence of SB220025 and SB203580 (specific inhibitors of p38 MAPK alpha/beta), progressed to the eight-cell stage with the same frequency as controls; however, treated embryos halted their development at the 8- …

Synapse, Alabama Health Libraries Association

Synapse - Newsletter of ALHeLa

This is the Spring-Summer, 2004 edition of the ALHeLa newsletter - Synapse.

Contents include:

• Annual Meeting
• OCLC/SERHOLD Holdings
• ALHeLA Executive Committee 2004
• ALHeLA Exec.Committee Mtg. 05/07
• ALHeLA Exec.Committee Mtg. 07/25

Veterans' Health Care: Balancing Resources And Responsibilities, Lisa Sprague

National Health Policy Forum

This paper looks at the health care benefits and services administered by the U.S. Department of Veterans Affairs. It examines management strategies adopted within the department to allocate resources, structure benefits, and improve quality. Some recommendations made by the General Accounting Office and the President’s Task Force to Improve Health Care Delivery for Our Nation’s Veterans are reviewed, in particular the emphasis of the latter on increased collaboration with the Department of Defense. Long-term proposals to balance service commitments and financing also are considered.

Three Steps Forward, Two Steps Back: Tobacco Policy Making In Nebraska, Andrew Wessel, Jennifer Ibrahim, Stanton Glantz

United States Public Health Resources

EXECUTIVE SUMMARY

• In 2002, 22.7% of Nebraskans over the age of 18 were current smokers, accounting for

approximately 389,000 smokers.

• Since 1995, the prevalence of adult tobacco use in Nebraska has remained about 1 percentage

point below the national average, but per capita tobacco consumption in Nebraska has been falling

more slowly than the Unites States as whole.

• The tobacco industry has directly been a major political force in Nebraska through lobbying and

campaign contributions. The tobacco industry spent over $1,027,000 on lobbying from 1997-2002.

The tobacco industry made direct campaign contributions to the members of the …