Medicine and Health Sciences Commons^™

Definitive Local Treatment For Metastatic Prostate Cancer: An Ncdb Retrospective Study, Paul Nagao, Jennica Luu, Olivia Gordon, Michael Whalen

GW Research Showcase 2021-2026

No abstract provided.

Evaluating The Prognostic Utility Of The Hematopoietic Cell Transplantation Comorbidity Index (Hct-Ci) In Children And Young Adults With Relapsed Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-All) Prior To Car T-Cell Therapy, Angela Sarkisian, Seth M. Steinberg, Bonnie Yates, Nirali N. Shah, Sara K. Silbert

GW Research Showcase 2021-2026

No abstract provided.

Outdoor Physical Activity As A Confounder For Vitamin D Status: A Scoping Review Protocol, Alia M. Badawi, Stephanie H. Vu, Patrick G. Corr, Leigh A. Frame

GW Research Showcase 2021-2026

No abstract provided.

Amyloidosis And Carpal Tunnel Syndrome: A Database Study Of Associated Risk Factors And Comorbidities, Sasha Narain, Amy Zhao, Peter Howard, Rachel Ranson, Alex Gu, Thakkar, O’Malley

GW Research Showcase 2021-2026

No abstract provided.

Evaluating The Use Of Hyperbaric Oxygen Therapy For Postoperative Ischemia In Breast Reconstruction: A Systematic Review, Ava Daniel, Kennedy Sun, Melanie Bakovic, Andeulazia Murdock, Jocelyn Fant, Bharat Ranganath

GW Research Showcase 2021-2026

No abstract provided.

The Impact Of An Interactive Social Media Intervention On Sexual Health Knowledge And Attitudes Of South African Adolescents Living With Perinatal Hiv: A Qualitative Assessment, Scarlett Bergam, Thobekile Sibaya, Nompumelelo Ndela, Mpume Kuzwayo, Messaline Fomo, Madeleine Goldstein, Jessica Haberer, Moherndran Archery, Brian Zanoni

GW Research Showcase 2021-2026

No abstract provided.

Mogamulizumab Retreatment For Cutaneous T Cell Lymphomas, Jason Krastein, Natasha Galasso, Ellie Casper, Tiffany Chang, Nivetha Ganesan, Niloufer Khan

GW Research Showcase 2021-2026

No abstract provided.

Socioeconomic Influence On Surgical Management And Outcomes In Patients With Craniosynostosis, Melanie Bakovic, Lilliana Starsiak, Ryan Mccaffrey, Spencer Bennett, Esperanza Mantilla Rivas, Monica Manrique, Gary F. Rogers, Albert K. Oh

GW Research Showcase 2021-2026

No abstract provided.

Analysis Of Electronic Health Record Data Identifies Features Associated With Future Genetic Evaluation, Elmer Rajah, Nhat Duong, Andrea Cohen, Eric Villain, Andrea Gropman, Seth I. Berger

GW Research Showcase 2021-2026

No abstract provided.

Acceptability Of Intramuscular Injection Of Tranexamic Acid In Postpartum Hemorrhage Prevention, S. Cordes, A. Nesson, J. Calderon, D. Abdelatif, H. Ahmadzia

GW Research Showcase 2021-2026

No abstract provided.

Community-Centered Learning: Themes From A Pilot Structural Racism Course For Medical Students, Julia Xavier, Maranda C. Ward

GW Research Showcase 2021-2026

No abstract provided.

Facilitators Of Parent Skill Use In Adhd Treatment, Ariana Adnani, Melissa Dvorsky, Lauren Friedman, Lauren Haack, Amanda Steinberg, Linda Pfiffner

GW Research Showcase 2021-2026

No abstract provided.

Dc-Sips: Decreasing Children’S Sugar Intake Through Pediatricians And Social Marketing, Shaleen Arora, Natalie Vallone, Allison Sylvetsky, Nia Bodrick

GW Research Showcase 2021-2026

No abstract provided.

Bodyweight Changes And The Incidence Of Atrial Fibrillation In Individuals With Obstructive Sleep Apnea, Jeffery Turley, Nicolette Friedman, Maritza Dowling, Ian Barrows, Zachary Falk, Dorys Chavez, Vivek Jain, Marco Mercader

GW Research Showcase 2021-2026

No abstract provided.

2023 Medical Student Research Day Abstracts, George Washington University

GW Research Showcase 2021-2026

Medical student research day is designed to highlight the breadth of research and scholarly activity that medical students have accomplished during their education at The GW School of Medicine and Health Sciences. All medical students are invited to present research regardless of the area of focus. Abstract submissions represent a broad range of research interests and disciplines, including basic and translational science, clinical research, health policy and public health research, and education-related research.

Reproductive Health In America: A History Of Patriarchal Control, Hailey Mccool

Undergraduate Research Conference

The United States is often referred to as the land of opportunity and the home of the free, yet today, those who challenge the patriarchal system are not treated fairly or equitably. Historically, from owning land to voting women have fought for the same rights enjoyed by men. The effort of early feminist movements paved the way for the Supreme Court to protect women’s reproductive rights through Roe v. Wade. For decades, women were able to make a choice regarding their reproductive health. However, in just the past year (2022), the Supreme Court ruled to strike down Roe v. …

Antagonistic Pleiotropy In Alzheimer's Disease, Annie Hollis

Undergraduate Research Conference

Apolipoprotein E (APOE) ε4 allele has been linked with Alzheimer’s disease; specifically having two copies of the APOE ε4 allele greatly increases the risk of developing Alzheimer’s disease in older age. Studies have attempted to relate an antagonistic pleiotropy hypothesis to this gene, i.e., the ε4 allele has positive effects on cognition and memory in early life and negative effects later in life. Many of these studies have had several limitations and conflicting results, such as testing adults in upper middle age or comparing the absence of the ε4 allele with the presence of at least one ε4 allele. Studies …

Covid-19 Vaccine Anxiety In The New Roaring 20s’, Sana S. Mahar

Research Days

Over the last two years, the discussion on vaccines has grown exponentially. The decision to be vaccinated, while to some is a “no brainer”, is now a debatable topic. The purpose of this presentation is to investigate some of the root causes for vaccine anxiety in the last two years. For this analysis, I will use reputable media sources to identify vaccine anxiety references within political, medical, and social media contexts and the types of anxiety conveyed; namely fear, anxiety, and distrust within vaccines. Politically in the last 2 years, Donald Trump’s ideologies of the danger of vaccinations lead to …

Ways That Nutrition Can Improve Mental And Physical Well-Being, Will Ravetto

Research Days

People are searching for things to do to help themselves feel their best. No matter if its to have energy to get you through the day or to do well on a big test or activity it all starts with what we eat to help us conquer every day. My research dives into the multiple food groups and concepts that create one’s diet. Exploring accessible nutritional foods that will improve immune health and longer lasting energy. This includes foods that aid recovery such as proteins, amino acids and even carbohydrates. I also, discourage foods one should stray away from like …

Sexual Knowledge And Wellness Of College Students, Aubrey Parker

Undergraduate Research Conference

Abstract: The purpose of this research project is to conduct further research on the use of a questionnaire developed by the fall 2022 FSC 330 class to assess sexual health knowledge of W students. I plan to study their use as a potential educational tool to provide sexual health knowledge to W students in addition to assessing their sexual health knowledge. The revised survey consists of topics that cover: contraceptives, women’s/ men’s sexual health and anatomy, gender/ sexual orientation, sexual coercion, STI’s, and lastly love/ communication. The survey we are currently making will have three different versions that are: feedback …

Phage Peptide Technology To Characterize Extracellular Vesicles In The Brain Tumors, Jadelynn Rudolf

Undergraduate Research Conference

Extracellular vesicles (EV) are lipid-bound containers derived from the endosomal membrane network or from the extracellular membrane of cells. They can carry proteins, lipids, miRNAs, and other molecules, and may be involved in intercellular communication via membrane-associated proteins. Glioblastomas (GBM) are aggressive cancers of the brain and spinal cord derived from astrocytes. Extracellular vesicles derived from glioblastomas can make their way through the blood brain barrier and find their way to different bodily fluids, and so could serve as biomarkers for this cancer. We have isolated phage-display peptides from a commercial library of random phage-displayed peptides that will bind glioblastoma …

Computational Evaluation Of Bioactive Compounds From Vaccinium Vitis-Idaea L (Ligonberry) For Treating Kras-Associated Lung Cancer, Ayooluwa Ilesanmi, Gbenga Dairo, Toheeb Balogun, Bibiire Awoyale

Undergraduate Research Conference

Lung cancer is the cancer of the lung's epithelial cells typically characterized by difficult breathing, chest pain, blood-stained coughs, headache, and weight loss. If left unmanaged, lung cancer can spread to other body parts. While several treatment methods exist for managing lung cancer, exploring natural plant sources for developing therapeutics offers great potential in complementing different treatment approaches. In this study, we concentrated on inhibiting the mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) by targeting an associated protein (Phosphodiesterase 6δ) to which KRAS form complexes. We evaluated bioactive compounds from Lingonberry (Vaccinium vitis-idaea L), adopting computational approaches such as …

Triazole Compounds – Potentials In The Treatment Of Cystic Fibrosis, Maggie Taylor

Undergraduate Research Conference

Cystic Fibrosis (CF) is a genetic disease that affects the respiratory and digestive system and is most common among Caucasians of Northern European origin. CF is caused by mutations in a membrane protein CFTR (Cystic Fibrosis Transmembrane-conductance Regulator). This mutation impairs the membrane protein’s chloride ion channel function. One of the most common CFTR mutations is the DF508 mutation that affects over 70% of CF cases. Our research has shown that the DF508-CFTR mutation can be partially reversed by physical and chemical means [Heda & Marino, BBRC, 271:659-664, 2000]. In cell lines expressing DF508-CFTR, synthetic anion carriers have shown to …

How Technology May Be Used For Future Disease Prediction: A Systematic Literature Review, Rich P. Manprisio, Mohammed Salam

Research Days

Exasperated by the current pandemic, our healthcare system continues to struggle with the accuracy and effectiveness of disease treatments. However, despite these growing challenges, technological advancements have aided potential disease prediction. There has been a positive correlation between utilizing technologies and leveraging them for disease predictions. Thanks to our continued reliance and technological advancement, current research shows that it has many viable options to aid the healthcare field. This systematic review looks at the current state of how technologies have been and can be used to improve healthcare.

Es-03 The Effects Of A Warmup Protocol Involving The Nordic Hamstring Exercise On Vertical Squat Jump Performance And Peak Muscular Activation, Reagan Hunter, Jeff Barfield

SC Upstate Research Symposium

Background: Vertical jumping is one of the most popular ways of assessing athleticism and power output of the lower body in both professional and recreational sport settings. Therefore, having access to an appropriate warmup protocol for enhancing this skill and the power output associated with it is essential for athletes whose success depends on the ability to perform it. Current literature demonstrates similar posterior kinetic chain muscle engagement during the vertical squat jump and during an exercise called the Nordic Hamstring Curl. The literature additionally demonstrates significant effects on strength and athleticism when the exercise is used in long-term training …

Gh-05 Exploring Drug Efficacy In The Pediatric Population: Determining The Differences Among Various Drug Classes, William F. Gardner Ii, Brooks T. Mcphail

SC Upstate Research Symposium

Exploring Drug Efficacy in the Pediatric Population: Determining the Differences Among Various Drug Classes

William F. Gardner II¹, M. Jacob Wurst¹, Brooks McPhail, PhD^1,2

¹University of South Carolina School of Medicine Greenville, Greenville, SC,

²Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Introduction: Pharmacodynamics is commonly defined as what the drug does to the body. The pharmacodynamic effects of a drug are required to determine its efficacy and safety. Due to the unique nature of pediatric development, and the challenges in doing research on children, the efficacy and safety of many drugs are …

Gh-06 Human Trafficking Simulation With Senior Nursing Students, Stephanie Barnhill, Monique Jones

SC Upstate Research Symposium

This poster shares information on a human trafficking simulation that can be used in healthcare courses. It includes an overview of human trafficking, risk factors for victims, and a script that students follow to make decisions as a victim and see the choices this vulnerable population must make.

Thought-provoking quotations from victims involved in human trafficking are shared, as well as resources for debriefing and discussion of healthcare worker roles, biases, and human tracking choices.

Mc-01 Identification Of Genes In Blastocoel Fluid Associated With Successful Ivf Outcomes Of Women Of Advanced Maternal Age, Hannah C. Archer, Thao Nguyen, Carson Collins, Kayla Vaillant, Molly Riehs, Sarayu Bethi, Renee J. Chosed

SC Upstate Research Symposium

Introduction: A patient may seek the use of IVF technology when they are struggling to become pregnant. To improve IVF outcomes, much research is focused on identifying markers to allow embryologists to transfer embryos with the greatest chance of a successful pregnancy. Women of advanced maternal age, which is thirty-five years and older have a lower chance of success on a first attempt with IVF, women at the age of 40 have a 9% chance of a live birth with IVF. Therefore, identification of an additional biomarker during preimplantation embryo development that is associated with successful implantation in AMA patients, …

Uh-02 A Case Report Of The Potential Link Between Pulmonary Fibrosis And Diabetes Mellitus, Bryson T. Rose, Isabella Nielson, Nnenna Igwe

SC Upstate Research Symposium

Pulmonary fibrosis is a chronic lung disease that is characterized by the progressive and irreversible scarring of the lung tissue. This scarring greatly diminishes the efficiency of pulmonary function. After being diagnosed with pulmonary fibrosis, patients live, on average, only three to five years. Diabetes mellitus is known to damage the tissue and blood vessels in organs such as the heart and kidneys due to increased intravascular pressure.

According to recent research, diabetes mellitus has also been linked to similar damage in the lungs. Additionally, a 2021 meta-analysis and systematic review of idiopathic pulmonary fibrosis suggests an association between diabetes …

Uh-03 A Case Report Of Saint’S Triad And The Diagnostic Implications For Clinicians, Catalina S. Molina, Nnenna Igwe, Hannah Young

SC Upstate Research Symposium

Abstract

Study Design- Case Report

Background- In the process of dissecting a 78-year-old male cadaver, the body was found to have an enlarged heart, an aortic aneurysm, a hiatal hernia, the stomach protruding through the thoracic cavity. The discovery led to the suspicion of a disease known as Saint’s Triad. Saint’s Triad is a manifestation of a general connective tissue disorder, resulting in the formation of hernias, diverticula, aneurysms, or COPD. The objective is to raise awareness of the Saint’s Triad as a disease and demonstrate its relationship with connective tissue disorders. This study also aims to encourage medical professionals …