Medicine and Health Sciences Commons^™

Association Between Smoking And Functional Outcome In Acute Ischemic Stroke Population Treated With Tissue Plasminogen Activator, Iretioluwa Ajani, Oluyemi R. Rotimi, Olubunmi Kuku, Ndukwe Kalu, Olakunle Oni, Christian Nwabueze, Thomas Nathaniel, Shimin Zheng

Appalachian Student Research Forum

Association between Smoking and Functional Outcome in Acute Ischemic Stroke Population Treated with Tissue Plasminogen Activator

Iretioluwa Ajani¹, Oluyemi Rotimi¹, Olubunmi Kuku¹, Ndukwe Kalu¹, Olakunle Oni¹, Nwabueze Christian¹,Thomas Nathaniel², Shimin Zheng^1*

¹Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614

²Department of Neurology, Department of Pharmacology, Physiology & Neuroscience, University of South Carolina School of Medicine, Columbia, SC 29208

*Sponsoring faculty

Background

The effect of smoking on outcome in acute ischemic stroke patients treated with …

The Use Of Functional Movement Screening Tests To Determine Injury Risks In Collegiate Soccer Athletes, Hannah Olds

Student Scholar Showcase

The Functional Movement Screening (FMS) was designed as a tool to identify compensatory movement patterns, often used with athletes. The purpose of this study was to find the relationship between FMS scores and injuries throughout the course of a Division III men’s and women’s Varsity soccer season. The effect of intervention with corrective exercises in improving total composite scores was also assessed. A pretest-posttest randomized control group design was used in which subjects (n=28, 50% male) completed the FMS Tests. FMS testing was performed 8 weeks apart. During the 8 weeks, subjects tracked injury occurrences and treatment subjects completed exercises …

Increasing Fruits And Vegetable Consumption Among Snap Recipients Through An Innovative Prescription Program: Appalachian Farmacy, Kiriinya Mwirigi, Beenish Kamran

Appalachian Student Research Forum

Introduction:

Food insecurity prevalence in Washington County, TN is 14.3% yet 61% of SNAP eligible residents are food insecure. Food insecurity is associated with inadequate consumption of fruits and vegetables, as well as increased risk of chronic disease. Tennessee ranks 47^th in the Nation with only 6.7% consuming the recommended fruits and vegetable intake. The Farmacy Pilot Program was developed to encourage increased consumption of produce and to reduce food insecurity among SNAP recipients.

Methods:

This program provided vouchers to SNAP recipients and their families to buy fresh fruits and vegetables at the farmers market and in the grocery …

Factors That Affect Early Sexual Initiation In A Sample Of College Students In North-East Tennessee: The Role Of Adverse Childhood Experiences, Economic Hardship, Family Structure And Religiosity., Oluyemi R. Rotimi, Hima Bindu Dubasi, Ruby Yadav, Mildred Maisonet

Appalachian Student Research Forum

Background

Normal adolescent development often involves sexual activity. Early sexual initiation poses a challenge to health and well-being. In 2015, Tennessee had the 9^th highest teen birth rate in the country. The structural, social and economic environments of growth define sexual risk taking, with poverty, Adverse Childhood Experiences (ACEs) religiosity and family structure known to affect adolescent and adult health. This study seeks to explore the effect of these factors on early sexual initiation.

Methods

A sample of college students taking the introductory psychology course participated in the study through the ETSU SONA system. They completed a self-reported web-based …

Physical Therapy Service-Learning In A Second World Country: What Are The Benefits?, Molly L. Koeneman, Katie B. Palmer, Jessie Bass

Student Scholar Showcase

Social responsibility and service are key initiatives within the physical therapy profession and within the Lynchburg College Doctor of Physical Therapy (DPT) program. Service-learning opportunities are offered in the DPT program within the country of St. Lucia on a yearly basis. The primary focus of this presentation is to evaluate the impact of this type of experiential learning on both students and the local community. During the 2018 service trip, the Minister of Special Education of St. Lucia provided special insight to our contribution to the special education schools in St. Lucia, which indicates the trip provides beneficial and sustaining …

Behavioral Correlates For Quitting Opioids Among Opioid-Dependent Pregnant And Non-Pregnant Women Of Childbearing Age In Rural Appalachia, Sindura Kompella, Sylvester Olubolu Orimaye, Nigel Dsouza, Karl Goodkin, Steven Kendell, Susan Wallace, Tracy Willson

Appalachian Student Research Forum

Background: The opioid epidemic is particularly worrisome in the pregnant population, wherein concerns are raised about the health of a mother and her child, resulting in an alarming incidence and prevalence of Neonatal Abstinence Syndrome (NAS). The 2016 National Survey on Drug Use and Health (NSDUH) show the rate of illicit psychoactive substance use among the females aged 12 or older was 15.5% in the past year. Among pregnant women aged 15 to 44, 6.3% were illicit psychoactive substance users. In Tennessee, the number of hospital discharged NAS cases from 2002 to 2013 increased from 1.50 to 16.6 cases per …

Lc Dpt Service Trip To St. Lucia: Following The Progress Of A 7 Y/O Boy Over 3 Years From Non-Ambulatory To Running With Peers, Brooke Panfil, Ainsley Reed

Student Scholar Showcase

In January of 2016, the Lynchburg College Doctor of Physical Therapy program formed the first group of 10 students and 2 professors that traveled to the island of St. Lucia to provide much-needed physical therapy services to the children in special education schools. During the initial visit, several students had the opportunity to work with a 5-year-old boy named Mark who had just learned to stand and presented with behavioral issues and lacked fine-motor skills. After spending only a couple hours with Mark, the students came up with a plan and some recommendations for Mark’s teachers with hopes to improve …

Being Observant: How Studying Michelangelo Can Improve Pt Practice, Andrew Lloyd, Erica Zachrich

Student Scholar Showcase

The field of physical therapy is swiftly transitioning from a formulaic biomedical model to a patient-centered biopsychosocial model, requiring clinicians to view their patients as a whole instead of as a sum of their parts. Integration of this concept into graduate health science education is variable across professions and amongst the same professional programs. Lynchburg College’s Doctor of Physical Therapy Program is pioneering an experiential learning course for graduate-level PT programs. “The Art of Anatomical Dissection: From Ancient Rome to the Renaissance” will transport students to the land of Da Vinci and Michelangelo, to study how the innovations of these …

Implementation Of The Banner Mobility Assessment Tool For Bariatric Patients, Nicole Benkert

Scholars Week

Abstract

The prevalence of morbidly obese patient within the United States is on a rapid incline. Evidence correlates an increase in patient falls, comorbidities, and hospital admission among this specific patient group. As a result, there is an increase in workload and injuries to staff as they tend to these patients. Healthcare facilities need to continuously update current patient handling programs and create specific policies for safely handling obese patients. Research suggests that Safe Patient Handling and Mobility Programs, as well as the Banner Mobility Assessment Tool (BMAT), have substantially decreased nurse injuries through a wide range of nursing specialties. …

The Effects Of Core Stabilization Training On The Performance Of Functional Tasks In Firefighters, Emily Maxwell

Student Scholar Showcase

The purpose of this study was to observe if core stabilization training plays a significant role in firefighter time-to-completion during a functional performance test. A within subjects study design was used in which subjects (n=13, mean ± SD age and body fat 33.7 ± 7.4 years, 25.79 ± 6.55 percent, respectively) completed two performance tests (pre and post core training), comprised of 7 firefighter-specific exercises performed while wearing a 22.68 kg weight vest to mimic typical firefighter equipment. Between testing sessions, subjects were prescribed specific core stabilization exercises to perform on their own 3+ days a week for a total …

Defining Relationships Between Medication Adherence, Medical Mistrust, And Self-Medication, Mikayla Carlton

Student Scholar Showcase

The purpose of this research is to delve into the topics of medication adherence, medical mistrust, and resulting or concomitant self-medication in order to define relationships and suggest solutions. There seems to be a relationship between greater medical mistrust and lower levels of medication adherence, as well as patients’ likelihood to self-medicate. Lack of medication adherence contributes to chronic disease and an increase in spending toward treatment both by the patient and the health-care industry over time. Medical mistrust has the potential to negatively influence medication adherence as it may prevent people from even seeking treatment. Self-medication may result from …

Sensory Integration In Saint Lucian Schools: A Case Study, Megan Lively Spt, Ashley Danielsen Spt, Leigha Schimmoeller Spt

Student Scholar Showcase

In January 2018, the Lynchburg College Doctor of Physical Therapy program sent a group of ten first- and second-year students to St. Lucia to provide therapy services to children in need across the island in five different special education schools. The group has been able to work hand-in-hand with the Ministry of Education in St. Lucia for the past three years in order to make a positive impact on the special education students and teachers. As the group did their evaluations this year, we noticed a trend that most of the students we worked presented with sensory integration dysfunctions and …

The Sensory And Textural Evaluation Of A St. Louis Style Butter Cake Made With Greek Yogurt As A Fat Replacer, Caprisse Johnson

Scholars Week

In modern America, many nutrition-related health issues are on the rise, including diabetes, obesity, and heart disease. Many nutrition professionals link the rise in these three diseases to the Western Diet, which includes a high fat and sugar content within its foods. Due to the increased consumption of this diet high in sugar and fat, obesity, heart disease, and diabetes rates seem to be rising. However, many people who eat this diet and are at risk for these complications, hesitate to change their diet because they feel that healthier alternatives bland in flavor or have a repugnant taste when compared …

Vte Prevention: A Risk Assessment Tool, Mary Gilkey

Scholars Week

VTEs are a leading cause of hospital deaths and cost healthcare systems billions. A risk assessment tool that correctly identifies at risk patients and provides appropriate prophylactic measures can decrease the rate of hospital acquired VTE.

Nursing Interventions For Neonatal Abstinence Syndrome, Sierra Harris

Scholars Week

This project serves to explore evidence for three nursing interventions aimed at neonatal abstinence syndrome including: breastfeeding, kangaroo care, and rooming-in. Many nursing interventions and policies are aimed at treating the symptoms despite limited research supporting their effectiveness. Further investigation into these interventions and policies regarding neonatal abstinence syndrome needs to be addressed in order to improve the quality of care for affected neonates and decrease the stigma surrounding neonatal abstinence syndrome.

The Effectiveness Of A "Patient Discharge Information" Booklet In Patient Education Program In Saudi Arabia, Amani Al Rebeh

Annual Graduate Student Symposium

The purpose of this research was to investigate the effectiveness of the Patient Discharge Information (PDI) booklet on the knowledge, attitude, and behaviors of participants who were cesarean patients in local hospitals in Saudi Arabia. This study investigated the following two research questions: (1) does the participant have information, resources, and understand basic personal health information regarding her health conditions including diagnosis, treatment, self-care management, medication instructions, normal expected symptoms, dangerous signs and what to do, as well as lifestyle changes?; and (2) how does patient discharge information provided by the hospital make a difference in participants’ knowledge, attitude, and …

An Exploration Of Global Women’S Health: Findings From A Pilot Online Course Elective For Health Sciences Studies At Gw, Marisa Cordon, Maranda Ward, Leslie Davidson

GW Research Days 2016 - 2020

In 1995, 189 countries endorsed the Platform for Action, designed to address issues of gender equality, including health. Despite this 23 year old initiative, women’s health issues continue to be a global crisis (WHO, 2015). The SMHS piloted an 8-week online 1-credit course in Fall 2017 to educate GW students on the top ten issues for women’s health delineated by the World Health Organization (WHO). Each of the eight weeks covered a core women’s health WHO issue while tying in a global human rights perspective. Issues included but were not limited to reproductive health, STIs, violence against women, to name …

The Pivotal Role Of Mri In The Diagnosis Of Listeria Rhomboencephalitis, K.R Uprety, M Reza Taheri

GW Research Days 2016 - 2020

Sixty-six year-old female presented to the Emergency Department with history of several days of headache, malaise, chills, and fatigue with accompanying nausea, vomiting, and inability to tolerate oral intake. She had no history of fever and remained afebrile at the time of presentation. Physical exam and immediate lab values were non-contributory; CSF was obtained and sent for analysis. The patient was placed preemptively on acyclovir, as viral meningitis was the admitting diagnosis. MRI of the brain showed abnormal FLAIR signal hyperintensity and enhancement involving the entire cisternal segment of the left trigeminal nerve, which extended dorsally along the nerve fiber …

Breast Lesions Detected Via Molecular Breast Imaging: Physiological Parameters Affecting Interpretation, Jason Ching, Rachel Brem

GW Research Days 2016 - 2020

Rationale and Objectives:

To evaluate correlations between molecular breast imaging (MBI) descriptor characteristics and positive predictive value (PPV) in detecting breast cancer.

Materials and Methods:

A retrospective review was performed on 193 suspicious findings from 153 women (31-81 years) with positive MBI examinations. We assessed associations between: (i) lesion pattern (mass vs. non-mass) and PPV; (ii) lesion pattern and suspected likelihood of cancer (low vs. moderate vs. high); (iii) background parenchymal uptake (BPU) (homogeneous vs. heterogeneous) and PPV; (iv) breast density (dense vs. non-dense) and PPV; (v) BPU and density.

Results:

One hundred ten of 153 patients were diagnosed with …

Total Hip Arthroplasty: Copd And Its Effect On Postoperative Complications, Camille Boustani, Shane A. Sobrio, Alex Gu, Chapman Wei, Andrew Holmes

GW Research Days 2016 - 2020

Introduction

The demand for Total Hip Arthroplasty (THA) has rapidly risen and continues to due to high success rates of this procedure and the growing aging population. Particularly in Chronic Obstructive Pulmonary Disease (COPD), studies have indicated an increased risk of various postoperative complications across several surgery types. Despite the prevalence of COPD, very little has been investigated regarding postsurgical complications in patients with COPD following a THA. The aim of the current study is to utilize the NSQIP database and determine differences in short-term postoperative complications after undergoing THA, comparing patients with and without COPD.

Methods

In total, 74,814 …

Cost-Effectiveness Of Alternative Anticoagulation Strategies For Postoperative Management Of Total Knee Arthroplasty Patients, Savannah R. Smith, Jeffrey Katz, Elena Losina

GW Research Days 2016 - 2020

Background: Anticoagulation is essential for deep vein thrombosis (DVT) and pulmonary embolism (PE) prevention following total knee arthroplasty (TKA). Some research has suggested that longer duration anticoagulation can substantially reduce the risks of DVT and PE; however, in the absence of definitive recommendations, physicians are left weighing the risks of DVT and PE against those of anticoagulation, including gastrointestinal (GI) and central nervous system (CNS) hemorrhage and increased likelihood of prosthetic joint infection (PJI). We conducted a cost-effectiveness analysis to evaluate the benefits and risks of 14- and 35-day therapy with the most commonly prescribed anticoagulants post-TKA.

Background: Anticoagulation is …

Piloting Carestart™ Rapid Diagnostic Test (Rdt) To Promote Glucose-6-Phosphate Dehydrogenase (G6pd) Screening In Malaria Endemic Community In Cambodia, Bertha Nyagaya-Wojnarski, +Several Additional Authors

GW Research Days 2016 - 2020

Background: Primaquine (PQ) is the only FDA-approved drug for radical cure of Plasmodium vivax (P.v) malaria, but treatment can result in life-threatening hemolysis if given to a glucose-6-phosphate dehydrogenase deficient (G6PDd) patient. Therefore, the G6PD status of the patient with P.v must be known prior to prescribing PQ. However, a patient’s G6PD status in rural malaria endemic settings is generally unknown, illuminating the need for reliable point of care G6PD diagnostic tests as a prerequisite to safely administer PQ. To increase community PQ access in Cambodia, performance of CareStart™ G6PD rapid diagnostic tests (RDTs) needs to …

Acute Hepatic Failure And Oral Amiodarone, Hani Alhamoud, Sivateja Mandava, Talal Alzahrani

GW Research Days 2016 - 2020

Introduction:

Amiodarone is associated with serious complications such as lung toxicity, thyroid dysfunction, and QT-prolongation. Further, hepatic failure from the intravenous (IV) formulation of amiodarone is described in numerous case reports and case series. Although there are reports of elevated liver enzymes from the oral formulation of amiodarone, to our knowledge, none have definitively identified a case of acute hepatic failure from the oral formulation alone. In this case, we report an instance of acute hepatic failure after increasing the oral amiodarone dosage as well as rapid recovery following cessation of the medication.

Case report:

A 61-year-old male with a …

Onyx Use In Extracranial Pathologies - A Retrospective Case Review, Faezeh Razjouyan, Rishi Sood, Alex Cho, Anthony Venbrux, Shawn Sarin

GW Research Days 2016 - 2020

Purpose:

Onyx is an embolic agent currently FDA approved for neurointerventional procedures such as in the treatment of aneurysms and arteriovenous malformations. Despite its limited indications, the agent's off-label use in the treatment of extracranial pathologies continues to increase. To date, there has not been a single-center study demonstrating a large number of cases demonstrating safe and effective peripheral embolization with Onyx.

Materials:

We performed a retrospective review of all cases that used Onyx between October 2010 and July 2016 at a single tertiary care academic university urban hospital. Institutional review board approval was appropriately obtained. Initial case selection was …

Lumbar Decompression Surgery: Does Chronic Steroid Use Increase The Risk Of Postoperative Infectious Complications? – A Study Of The National Surgical Quality Improvement Program (Nsqip) Database, Shane Sobrio, Mikel Thista, Raj Rao, Alex Gu, Chapman Wei, Warren Yu

GW Research Days 2016 - 2020

Intro: It has long been established that corticosteroids have a negative impact on the human immune system’s ability to function at an optimal level. Many past studies have shown that patient’s will have higher rates of infection if they are taking chronic steroids. What has yet to be established is just how much of an increased risk patients on chronic steroids have for infection after undergoing lumbar decompression surgeries, of which there are thousands per year. We hypothesize that patients on chronic steroids will have higher rates of surgical site infections and higher rates of other infections (UTI, pneumonia, etc.) …

Urinary Tract Infection In Children With Spina Bifida And Spinal Cord Injury., Obumneke Amadi, Harolyn Belcher

GW Research Days 2016 - 2020

Introduction: Urinary tract infections (UTI) are one of the most common bacterial infections (Schappert & Rechtsteiner, 2008; Litwin et al., 2005). Data from the National Ambulatory Medical Care Survey estimated that UTI caused 8.1 million physicians visits (Schappert & Rechtsteiner, 2008). Children with spina bifida (SB) and spinal cord injury (SCI) are at high risk for UTI (Ouyang et al., 2010; Nair et al., 2005). The purpose of this study was to examine the organisms associated with UTI in the population of children with SB and SCI who were treated in out-patient and in-patient settings at the Kennedy Krieger …

Improving Admission Medication Reconciliation Completion At Gw Hospital, Amanda Nizam, Andrew Shelton, Dembi Iyekegbe, Matthew Cichocki, Puya Jafari, Paul Pickmans, Jessica Logan, Cherinne Arundel

GW Research Days 2016 - 2020

Background: Medication errors represent a major cause of adverse events in hospitalized inpatients. 27-83% of hospitalized patients will have at least one discrepancy in their medication history at admission, with 11%–59% of errors having clinical importance. Current processes for completing admission medication reconciliations are ill-defined, further increasing the risk of errors. Implementation of a standardized medication reconciliation process has led to a reduction in medication errors. Aim Statement: To increase the number of admission medication reconciliations completed within 48 hours of admission to GW Hospital by 25% over three months. Methods: From September 2017 until December 2017, an educational intervention …

Pupillometric Assessment Of Small Doses Of Opioid In A Pediatric Population, David Strum, Elizabeth Malphrus, Kevin Jackson, Julia Finkel

GW Research Days 2016 - 2020

According to the CDC, opioid prescriptions in the United States have more than tripled from 1999-2014, which has correlated with the staggering increase in opioid-involved drug overdose deaths. This pattern of prescription is thought to be a major contributory factor to the increase in drug overdose in America, as four out of five new heroin users started by misusing prescription painkillers. Providers need the means to objectively monitor analgesic efficacy of treatment in patients with pain to mitigate unnecessary analgesic prescribing.

It is well established that mu opioid agonists like morphine cause miosis, an effect to which tolerance does not …

Recurrent Episodes Of Acute Pancreatitis Present To The Ed With More Severe Disease By Ct Than First-Time Acute Pancreatitis, Maryam Boumezrag, Hamza Ijaz, Lorna Richards, Sormeh Harounzadeh, Angeline Johny, Paige Kulie, Caitlin Davis, Yan Ma, Maxine Le Saux, Andrew C. Meltzer

GW Research Days 2016 - 2020

Study Objective: Approximately 30% of patients with one episode of acute pancreatitis experience a recurrent episode. The objective of this study is to compare the severity of the first-time episode versus recurrent episodes of acute pancreatitis based on CT scan.

Methods: This study was conducted as part of a retrospective chart review at a single academic urban emergency department from 2012-2016. Criteria for inclusion included clinical symptoms of pancreatitis, age greater than or equal to 18 years, ED diagnosis of acute pancreatitis, and, an abdominal CT scan within 24 hours of triage. Exclusion criteria were traumatic cause of acute pancreatitis …

The Association Of Polymorphism Rs3736228 Within The Lrp5 Gene With Bone Mineral Density In A Cohort Of Caucasian Young Adults, Mohamed J. H. Al-Amoodi, Whitney Jones, Danny Lee, Steven Mckenzie, Helen C. Miller, Zach Zeller, Seth Stubblefield, Susan Knoblach, Heather Gordish-Dressman, Dustin Hittel, Laura L. Tosi

GW Research Days 2016 - 2020

INTRODUCTION: Osteoporosis is a significant burden for our aging population. Developing a better understanding of the genetic underpinnings of poor bone quality may assist in the future development of prevention strategies. Correa-Rodriguez et al. have identified a group of single nucleotide polymorphisms (SNPs) that were associated with bone mineral density (BMD) in a population of Spanish Caucasians. In particular, they found that SNP rs3736228 in the low-density lipoprotein receptor related protein 5 (LRP5) gene had an influence on BMD. While the role of LRP5 in the Wnt canonical pathway has been fairly well characterized, its association with phenotypic BMD and …