Medicine and Health Sciences Commons^™

Ventilatory And Gas Exchange Kinetics In Response To Progressively Increasing Work Rate Transitions In Humans., Alexandra Ward

Undergraduate Student Research Internships Conference

No abstract provided.

Scaling-Up, Justine A. Dryburgh

Undergraduate Student Research Internships Conference

Research outputs for Justine Dryburgh's USRI 2021.

Changes In Children's And Parents' Physical Activity Levels During The Covid-19 Pandemic: A Literature Review, Kshitija Mundle

Undergraduate Student Research Internships Conference

Objectives: The purpose of this literature review was to gain an understanding of the impact that the COVID-19 pandemic and associated closures have had on the physical activity levels of children (ages 0-12) and their parents/guardians.

Methods: To identify relevant literature, a comprehensive database search was conducted. Specifically, studies including keywords: parents, children, physical activity, and COVID-19 and their related terms published between March 2020 and August 2021 were screened for inclusion.

Results: A number of articles have been published which suggest that structured/organized physical activities and team play opportunities have decreased during COVID-19 restrictions, while home-based unstructured play and …

Effect Of Carbon Monoxide Releasing Molecule 3 (Corm - 3) On Platelet Adhesion To Human Brain Microvascular Endothelial Cells, Najat S. El-Farra

Undergraduate Student Research Internships Conference

Sepsis is characterized by the widespread inflammation of the body. Systemic inflammation activates and recruits inflammatory cells (e.g., leukocytes) and platelets to the affected organs.

During these inflammatory conditions, human brain microvascular endothelial cells (hBMEC) and platelets both upregulate adhesive molecules rendering platelets to adhere to hBMEC.

Although carbon monoxide is thought of as a toxic molecule to many, previous work shows its anti-inflammatory properties. Evidence has shown carbon monoxide-releasing molecules (e.g., CORM-3; that release small, non-toxic amounts of CO) can combat the effects of severe inflammation in several in vivo animal model.

In this current study, we are looking …

The Influence Of The Social Determinants Of Health On Para-Sports Involvement Throughout The Caribbean And Americas, Laura Misener

Undergraduate Student Research Internships Conference

As the number of individuals with a disability grows worldwide, the Paralympic Games and para-sports have seen a growth in participation (WHO, 2011). However, international sporting competitions including the Paralympic Games remain dominated by developed countries (Andreff, 2001). In the last Paralympic Games, the USA, Canada, and Brazil made up nearly 70% of participants from the North and South American region with 17 of the 28 committees sending five or less participants (Maleske & Sant, 2020). The present study investigates the social and cultural determinants in the Caribbean and Americas of para-sport participation in the region and their relation to …

Investigating The Statistical And Policy Frameworks Used To Gauge Potential Pharmacotherapy Recalls: A Scoping Review, Benson Law

Undergraduate Student Research Internships Conference

Paramount attention is often afforded to pharmacotherapies being brought to market. The anticipation from companies, their shareholders, and the patients poised to benefit are met with stiff statistical and methodological requirements set forth by Health Canada’s Health Products and Food Branch (HPFB). Once a pharmacotherapy has been approved by the HPFB, however, the onus to monitor these drugs falls largely on the shoulders of Health Canada, the manufacturers, and to a lesser degree, the Drug Safety and Effectiveness Network (DSEN). This scoping review identified existing pharmacovigilance frameworks recommendations from SCOPUS, PubMed and EMBASE and compared the guidelines employed by Health …

Comparing Semi-Automated Segmentation Of Traditional-Resolution And High-Resolution Hyperpolarized 129xe Mri On Covid-19 Survivors, Tingting Wu

Undergraduate Student Research Internships Conference

Hyperpolarized gas MRI using inert gases like Xe is a valuable tool in visualizing lung ventilation in patients, and can be used as a longitudinal monitoring tool for patients with lung diseases. However, use of this method requires segmentation and quantification of parameters such as ventilation defect percentage (VDP), which is often very subjective depending on the observer. This study aimed to determine the accuracy and consistency of VDP calculation using the same MRI scans from COVID-19 patients, but with high resolution and low (traditional) resolution versions. Using a MATLAB script developed previously, it was found that in general, using …

The Role Of Pannexin 3 In Forced Exercise Bone Remodelling And Its Potential Implications For Osteoarthritis, Justin Tang

Undergraduate Student Research Internships Conference

Exercise such as running has been hypothesized to be a factor of osteoarthritis development. However, the relationship is unclear as differences in genetic backgrounds may influence the risk of osteoarthritis (OA). The gene Panx3 codes for the Pannexin 3 protein (PANX3), a mechanically sensitive channel that allows for the passage of various signalling molecules in both chondrocytes and osteoblasts (Boassa et al., 2007; Penuela et al., 2013; Zhang et al., 2021). We have previously shown PANX3 to be protective in traumatic osteoarthritis, however beneficial in age-induced osteoarthritis (Moon et al., 2021), suggesting that PANX3’s role in osteoarthritis development …

Understanding The Role Of Rhamm In Tumor Load– Mediated Tumor Invasiveness Of Triple Negative Breast Cancer, Ashwin Sritharan, Britney Messam

Undergraduate Student Research Internships Conference

1.Compare the levels of proliferation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids as determined by ki67 and Caspase 3 signaling 2.Compare levels of RHAMM, CD44, Has2, and p-ERK activation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids

Characterizing Cancer Associated Fibroblasts From Pancreatic Ductal Adenocarcinoma Patient Samples, Rachel Lu

Undergraduate Student Research Internships Conference

No abstract provided.

Towards Standardized Assessment Of Paraspinal Muscle Using Mri, Hamza Mirza

Undergraduate Student Research Internships Conference

• Common methodological variations in paraspinal muscle (PSM) measurement

significantly affect cross-sectional area and fat percentage measurements.

• The lack of standardization of PSM measurements complicates

comparisons of findings between studies and prevents pooling of

data for meta-analyses.

• Standardization in PSM measurements is needed to move the field forward

Social Cognition Across Eating Disorders: A Systematic Review, Jina C. Kim

Undergraduate Student Research Internships Conference

Social cognition refers to the cognitive processes involved in social interactions. Deficits in social cognition may play a role in the onset and maintenance of eating disorders (ED). The goal of this review was to examine the current literature on social cognition across EDs, specifically, anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED).

The search revealed 79 studies which were organized according to six domains of social cognition: alexithymia, theory of mind, empathy, social processing, emotion recognition, and emotion processing. Most studies examined AN, finding evidence for deficits in some domains of social cognition. Literature on BN …

Interdisciplinary Development Initiative (Idi) Entitled “Emerging Team Initiative To Reduce Inequities In Maternal And Child Lifestyle Health, Rozhan Momen

Undergraduate Student Research Internships Conference

Interdisciplinary Development Initiative (IDI) entitled “Emerging team initiative to reduce inequities in maternal and child lifestyle health"; an environmental scan of the faculty of health sciences and other western faculties, Brescia university college and research institutes as well as community agencies with similar interests.

Generating Cisplatin Resistant Hpv-Positive Hnscc Cell Lines, Temitope Akintola

Undergraduate Student Research Internships Conference

Acquired or innate resistance to chemotherapy poses a significant challenge in the treatment of head and neck squamous cell carcinomas (HNSCC). HNSCCs are often treated with a combination of surgery, radiation and chemotherapy, with cisplatin being a standard-of-care chemotherapy drug. Human Papillomavirus (HPV) associated HNSCCs have better treatment outcomes and prognosis when compared to HPV- HNSCCs. However, a subset (15-20%) of HPV+ patients develop treatment resistant diseases. The purpose of this study is to generate in-vitro models of cisplatin resistance in five HNSCC cell lines. We aim to characterize the generated cells in order to identify target genes that may …

Biomechanical Differences Between Recreational And Collegiate Runners, Ryan J. Evans

Undergraduate Student Research Internships Conference

Using a pre-existing sample and data, various forces and limb positions were analyzed to determine movement pattern differences between recreational and collegiate level runners that influence injury and performance factors.

Mental Health And Paramedics, Anna Ding

Undergraduate Student Research Internships Conference

Paramedics on the front lines of Ontario’s COVID-19 pandemic response play an imperative role in patient care and infection management. They take measures to limit risks of contamination to themselves, other patients and providers while delivering this essential healthcare service but are often less recognized for their efforts. From 21 interviews conducted between April to June 2020, a secondary analysis on specific mental health concerns and stressors was completed. Preliminary findings include several pandemic related stressors and long-term occupational health and safety risks. This leads to further discussion on moral distress, and the possible risks of burnout. For public health, …

Understanding The Impact Of Covid-19 On Physical And Mental Fatigue In Youth With Cerebral Palsy, Nathan Wc Yang Mr.

Undergraduate Student Research Internships Conference

This explorative study examined the impact of the COVID-19 pandemic, lockdowns, and social distancing on mental and physical fatigue and life role participation of youth with CP. Quantitative data included results from the Fatigue Impact and Severity Self-Assessment (FISSA), Child & Adolescent Scale of Participation (CASP) and the Participation and Environment Measure for Children and Youth (PEM-CY).

The Experiences Of Healthcare Workers And Lawyers Engaging In Remote Work, Desha Puri, Tracey L. Adams Dr.

Undergraduate Student Research Internships Conference

This study aims to compare the experiences of healthcare workers and lawyers engaging in remote work during the Covid-19 pandemic. The research poster presents a content analysis of the current research on the experiences of professions in the two fields mentioned above. In engaging in content analysis, the study advances a select number of thematic value codes that effectively characterize the similarities and differences between the two professions. With these thematic values codes, it has been found that the healthcare profession and law profession have had a similar experience working from home. With these similarities and differences, one can propose …

A Prediction Rule To Guide Jak2 Mutation Testing In Patients With Elevated Hemoglobin Levels, Ian Cheong

Undergraduate Student Research Internships Conference

No abstract provided.

Centre For Activity And Aging (Ccaa), Brinda Patel

Undergraduate Student Research Internships Conference

No abstract provided.

Integrating Residents As Partners In Long-Term Care (Ltc) Research, Ruthie Zhuang

Undergraduate Student Research Internships Conference

This research poster summarizes patient-engagement throughout the study "COVID-19: Implementation of virtual P.I.E.C.E.S for LTC resident care planning with family to build and sustain team collaboration and workforce resilience". It describes two implementation frameworks (CFIR and PRISM) as well as two patient-engagement tools (PEIRS and PPEET) in relation to the study. Lastly, it offers preliminary insights into the current landscape of patient-engagement in research.

Optimizing Hospital Capacity To Deal With Hallway Medicine, Megan Wismer

Undergraduate Student Research Internships Conference

A model adapted from Hillier and Liebermann, 2017 that optimizes hospital capacity to deal with hallway medicine.

Ct And Hyperpolarized 129xe Mri Structure-Function Relationships Of Post-Acute Covid-19 Syndrome, Vedanth Desaigoudar

Undergraduate Student Research Internships Conference

No abstract provided.

Depression & Anxiety In Brain Vs. Body Trauma Patients, Olivia Mercier

Undergraduate Student Research Internships Conference

No abstract provided.

Trouble Source Repair (Tsr) Coding, Kyla M. Finlayson

Undergraduate Student Research Internships Conference

Throughout the year I have worked with a team analyzing transcripts of conversations with individuals with a cognitive and a sensory impairment to identify causes and patterns of communication breakdowns and repairs. This presentation describes trouble source repair (TSR) coding and how it is used to identify and analyze miscommunications and misunderstandings in conversations. In the future, this research will be used to identify patterns in conversation and external variables that often create communication breakdowns in order to improve care for persons living with dementia and a sensory impairment.

The Effect Of Sprint Interval Training And Intermittent Fasting On Cognitive Function, Dana Taghaddos

Undergraduate Student Research Internships Conference

This study will explore how a combination of a time-restricted eating (TRE) strategy and a sprint interval training (SIT) exercise program will affect cognitive function. Both TRE and SIT are easily implemented lifestyle habits that have been shown to present significant brain challenges. Participants will be randomized into 3 groups: either SIT + TRE (Group 1), SIT alone (Group 2), or TRE alone (Group 3). We will assess acute effects (single day of TRE, followed by a single session of SIT the next day), and the effects over a 6 week period. The SIT protocol consists of four 30 second …

Is Tik-Tok Body Positive?, Grace N. Solylo

Undergraduate Student Research Internships Conference

No abstract provided.