Medicine and Health Sciences Commons^™

Breast Lesion Localization: Savi Scout, Madison L. Keegan

Medical Imaging Senior Posters

Breast Lesion Localization: Savi Scout

Madison Keegan

Faculty Advisor: Dr. Elaine Halesey, Ed.D., R.T.(R)(QM)

The Savi Scout is a localization procedure used to help identify non-palpable breast lesions under mammographic or ultrasound guidance, by way of placement of a non-radioactive reflector through a delivery system. The modality of mammography uses screening and diagnostic exams by creating images of the breast to better visualize anatomy as well as possible lesions. The radiographic detail determines the type of breast tissue such as fatty, dense, or extremely dense and with age the tissue type can change. Non-palpable breast lesions are identified with imaging …

Interventional Balloon Kyphoplasty In Multiple Myeloma Patients, Mary Dziadosz

Medical Imaging Senior Posters

This poster project explains an interventional radiology (IR) procedure called Balloon Kyphoplasty (BKP). BKP is a procedure that involves the insertion of cement into the vertebral column due to vertebrae fractures throughout the spine. Vertebral fractures can happen due to a number of reasons, however, multiple myeloma is the main focus of this project. Multiple Myeloma (MM) is the second most hematological malignancy and there is no cure. MM affects several parts of the body but the most common are the skull, vertebral column, long bones, and the hip and pelvis region. There are several advantages to having BKP done. …

Interventional Breast Imaging, Agripina Torres

Medical Imaging Senior Posters

Interventional breast imaging is essential in the diagnosis of abnormal findings in the breast tissue. Interventional breast imaging began as an open excision; the breast was biopsied through a surgical procedure that required the whole breast to be excised, thus allowing a sample of the breast tissue to be obtained. With this type of biopsy, the patient would have a longer recovery time, a higher cost, and, in some cases, unnecessary excisions. Image guided breast intervention, however, has led to the decline of open excisions. Biopsies performed under the guidance of an imaging modality allow breast interventions to be safe, …

The Impact Of Covid-19 On Radiation Oncology Treatments, Lauren Fink

Medical Imaging Senior Posters

When the COVID-19 pandemic began, hospitals became overwhelmed. There was a lack of personal protective equipment (PPE) and a lack of capacity within emergency departments, which caused a panic amongst medical facilities. Facilities were forced to prioritize patients and cancel appointments that were not urgent. Many doctors’ appointments were switched to tele-visits to limit exposure to the virus and to allow priority to COVID-19 patients. Not only were diagnostic testing and treatments postponed or canceled, but news was published that those who were immunosuppressed need to take extra precautions because the risk of fatality is greater for those with preexisting …

Digital Breast Tomosynthesis For Dense Breasts, Emily Kerbaugh

Medical Imaging Senior Posters

Digital breast tomosynthesis (DBT), also referred to as three-dimensional digital mammography provides a new technique that can aid in dense breast imaging. Mammography is the process of creating images of the breast for screening and diagnostic purposes by using low dose radiation. Screening mammograms are performed once a patient is age forty and then annually after that. It is used to provide an earlier detection of breast cancer for a better chance of survival. Diagnostic mammograms are performed when a patient has a strong family history of breast cancer or clinical evidence, such as, a breast lump. Most cancerous lesions …

What Is Scannable? An Mri Safety Guide, Michael Burcescu, Ravi Patel, Robert Hessemer, Peter Lore, Sriharsha Kota, Guarav Kumar

West Florida Division GME Research Day 2020

Supernumerary MRI protocols and recommendations exist to guide physicians at the forefront of patient care. While urgent imaging may be necessary for critical patients, inadvertent imaging of implantable devices can incur serious morbidity and mortality[11]. The American College of Radiology published a 30-page manual in 2013[1] on MRI safe practices and releases yearly updates with critical information separately[2]. There is increased utilization of advanced imaging modalities, especially among academic institutions[3]. Physicians are hard pressed to maximize efficiency; uncertainty delays imaging. Moreover, inappropriate orders delay appropriate management. We present pertinent and often questioned considerations in a comprehensible format along with devices …

Frequency And Perceived Authenticity Of Social Determinants Of Health Discussion By Medical Trainees, Priyadarshini Chandrashekhar, Emily J. Noonan, Laura A. Weingartner

Undergraduate Arts and Research Showcase

Introduction

Social determinants of health (SDOH)—the conditions in which people live, learn, and work—play a vital, but often neglected role in shaping a community’s health. SDOH influence risk factors for disease and access to healthcare, consequently promoting health inequities among different populations. Examining how providers discuss SDOH with patients can identify opportunities to better integrate social context into care.

Methods

We analyzed standardized patient (SP) encounters of rising UofL M3 trainees to 1) determine whether SDOH are integrated into healthcare conversations, and 2) investigate what constitutes an authentic conversation to identify how trainees can better express interest in a patient. …

Screening For E-Cigarette And Tobacco Use In Standardized Patient Encounters, Michael A. Schmidt, Emily J. Noonan, Laura A. Weingartner

Undergraduate Arts and Research Showcase

E-cigarette usage has grown significantly in recent years, with over 5 million US middle and high school students reporting recent usage. The long-term health consequences of these devices are still being investigated, but it is known that e-cigarette aerosol could contain harmful substances including nicotine, heavy metals, and carcinogens. Therefore, it is important for physicians to ask patients about e-cigarette usage specifically, as this may contribute to future health problems. The goal of this study was to investigate if and how medical students screen for e-cigarette usage. Screening language was reviewed in standardized patient encounters, which are a type of …

A Qualitative Descriptive Analysis Of Erowid Gabapentinoid Forum Posts, Haylee E Figg Rn Bsn Student, Rachel Vickers-Smith Phd, Mph

Undergraduate Arts and Research Showcase

Purpose/Background: With increased controls on opioid prescribing, the CDC has suggested prescribing gabapentinoids as a first-line alternative to opioids for pain. However, there have been an increasing number of reports of gabapentinoid misuse. Drug use forums are online spaces where individuals can anonymously post about their drug use experiences and may provide insight on gabapentinoid misuse. The purpose of this study was to extract and analyze posts from the drug use forum, Erowid, to examine reports of gabapentinoid misuse.

Methods: Data for the study was drawn from 53 pregabalin forum posts and 89 gabapentin forum posts by unique usernames. In …

An Occupational Hygiene And Safety Primer, Volume 2, Tim Ryan

OHIO Open Faculty Textbooks

Intended to teach the basic tenets of occupational hygiene and safety to a wide variety of undergraduate college students with quite diverse backgrounds, the information in these volumes is open-sourced from a variety of experts on the subject.

An Occupational Hygiene And Safety Primer, Volume 1, Tim Ryan

OHIO Open Faculty Textbooks

Intended to teach the basic tenets of occupational hygiene and safety to a wide variety of undergraduate college students with quite diverse backgrounds, the information in these volumes is open-sourced from a variety of experts on the subject.

Paroxetine Is Pro-Inflammatory In Human Brain Microvascular Endothelial Cells, Syeda Hashimi, Sulay Patel, Omar Hassan, Bukola Odeniyi

Graduate Research Posters

BACKGROUND: Paroxetine is an antidepressant that is widely used. However, Paroxetine possesses anticholinergic properties which may contribute to cognitive decline in older adults. Surprisingly, the mechanisms of the cognitive decline of anticholinergic drugs in older adults remains elusive. A hypothesis is that a loss of cholinergic signaling is pro-inflammatory in the brain. We designed experiments to determine if Paroxetine is pro-inflammatory in Normal Human Brain Microvascular Endothelial Cells (NHBMECs).

METHOD: NHBMECs were grown at 5% CO2, 37C and 95% relative humidity until 90% confluent. NHBMECs were treated with the RNA free water as control, Paroxetine as 1.67x 10 4 mM/mol, …

Addressing Minority Health Disparities In Richmond: Results From A Health Needs Assessment Of A Southside Community, Nixon Arauz, Ma, Shanteney Jackson, Ma, Robert A. Blanco, Mph

Graduate Research Posters

Background:

Evidence shows the effectiveness of integrating community health workers (CHWs) into care models serving high-risk patients to reduce emergency department (ED) use, increase primary care use, and address adverse social determinants of health (SDH). The Southwood Resource Center, part of a network of clinics established by Richmond City Health Department, utilizes CHWs to address disparities affecting underserved populations through primary care referrals and additional resource linkages. Local student-volunteers in partnership with CHWs conducted a community needs assessment to identify patient resource gaps, aid in design and implementation of SDH interventions, and examine the relationship between chronic disease management and …

Dendrimer Conjugation Enhances Tumor Penetration And Cell Kill Of Doxorubicin In 3d Coculture Lung Cancer Models, Rashed Almuqbil, Rodrigo S. Heyder, Elizabeth R. Bielski, Mikhail Durymanov, Joshua J. Reineke, Sandro R. P. Da Rocha

Graduate Research Posters

Background: Doxorubicin (DOX) is a potent chemotherapeutic widely used for solid tumors (1). Despite high efficacy in 2D cell culture, DOX efficacy does not translate to in vivo lung cancer models (2). Major side effects such as cardiotoxicity may be alleviated with nano-based drug delivery systems (nanoDDS). However, tumor penetration of DOX and DOX-nanoDDS is largely unknown and is an additional barrier to effective clinical therapy (3). Here we describe a nanoDDS capable of enhancing the penetration of DOX.

Methods: DOX was conjugated to generation 4 poly(amido-amine) dendrimers through (GFLG) tumor- liable bond. G4SA-GFLG-DOX was synthesized/characterized. spheroids were formed of …

Vascular Dysfunction And Posttraumatic Stress Disorder: Examining The Role Of Oxidative Stress And Sympathetic Activity, Jennifer Weggen, Aaron Autler, Gina Tuzzolo, Austin C. Hogwood, Ashley M. Darling, Kevin P. Decker, Ryan S. Garten

Graduate Research Posters

Purpose: The physiological manifestations of posttraumatic stress disorder (PTSD) have been associated with an increase in risk of cardiovascular disease (CVD) independent of negative lifestyle factors. The goal of the study was to better elucidate the mechanisms behind the increased CVD risk by examining peripheral vascular function, a precursor to CVD. Moreover, this study sought to determine the role of oxidative stress and sympathetic nervous system (SNS) activity in PTSD-induced vascular dysfunction.

Methods: Sixteen individuals with PTSD (10 women, 6 men; age 24 ± 4 years), and twenty-four healthy controls (CTRL; 15 women, 9 men, 24 ± 4 years), participated …

“How Am I Supposed To Feel?”: Social Support And Black Mothers’ Infant Feeding Decisions, Hannah M. Ming, Cecilia Barbosa

Graduate Research Posters

Background: Many of the adverse health outcomes that breastfeeding protects against disparately affect black mothers and children; however, black mothers are the least likely racial group in the U.S. to breastfeed. Black mothers have indicated that breastfeeding barriers include a lack of social support. Qualitative studies examining such breastfeeding barriers often focus on women who have unsuccessfully breastfed and fail to define the experiences of women who have successfully breastfed. This study aims to identify the impacts of social support on the infant feeding decisions of black women with varying levels of breastfeeding success.

Methods: Twenty-five black women were interviewed …

Dyrk1a And The Cell Cycle, Holly Byers, Larisa Litovchick, Md, Phd

Graduate Research Posters

The ability to halt the cell cycle is critical for cells to maintain tissue and organ size, to suppress tumors and abnormal growth, and exists as a helpful mechanism to pause the cell cycle for DNA repair. DYRK1A is (dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A) a human gene found on the long (q) arm of chromosome 21, which is known to be involved with nervous system development, cell growth and division, and neuronal differentiation. In glioblastoma cells grown in vitro (T98G cell line), there are three copies of DYRK1A, which have dosage- dependent effects on the cell, including association with …

The Effects Of A High Fat Meal On Blood Flow Regulation During Arm Exercise, Alexander Chiu, Lauren Pederson, Jeremy O. Via, Natalie J. Bohmke, Jacob Richardson, Aaron Autler, Hunter Reed, Eric Henderson, R. Lee Franco, Ryan S. Garten

Graduate Research Posters

A diet high in saturated fats results in endothelial dysfunction and can lead to atherosclerosis, a precursor to cardiovascular disease. Exercise training is a potent stimulus though to mitigate the negative effects of a high saturated fat diet; however, it is unclear how high-saturated fat meal (HSFM) consumption impacts blood flow regulation during a single exercise session.

PURPOSE: This study sought to examine the impact of a single HSFM on peripheral vascular function during an acute upper limb exercise bout.

METHODS: Ten young healthy individuals completed two sessions of progressive handgrip exercise. Subjects either consumed a HSFM (0.84 g of …

Clinical Reconciliation Of Patient Social Context And Implementation Of Preventive Care Guidelines, April Williams

Graduate Research Posters

Background

Preventive care practice guidelines are disseminated regularly through federal and scientific groups as a way of promoting best practices and evidence-based health promotion. Yet rates of their implementation are historically low and complex, with cited barriers including limits on physicians’ time, knowledge or attitudes; and external factors related to the guideline itself, the clinical environment, or patient factors. The objective of this qualitative research is to understand how primary care clinicians and staff reconcile perceived patient-level factors and implementation of preventive care guidelines.

Methods

Key informant interviews (n=23) with 14 clinicians and 9 office managers from 14 primary care …

Offering The Choice Of Self-Administered Oral Hiv Testing (Chivst) Among Long-Distance Truck Drivers In Kenya: A Trial-Based Cost-Effectiveness Analysis, Deo Mujwara, April D. Kimmel

Graduate Research Posters

Background: Long distance truck drivers (LDTD) are a high-HIV-risk population facing unique healthcare barriers due to continuous travel and irregular schedules, and may require targeted, resource-intensive strategies for HIV-test uptake. We conducted a trial-based cost-effectiveness of CHIVST among LDTD in Kenya.

Methods: Effectiveness data came from a randomized-controlled trial of CHIVST (n=150) versus provider-administered testing (n=155). Economic cost data came from the literature and reflected a societal perspective. Generalized Poisson and linear-gamma regression models estimated the effectiveness (relative-risk) and incremental costs (2017 I$), respectively, with incremental effectiveness calculated as the reciprocal of the absolute risk difference and reported as the …

Six Weeks Of Resveratrol Improves Cardiovascular Health In Patients With Copd, Rebekah Lavender, Kolton Cobb, Kendall Goldman, Paula Rodriguez-Miguelez Phd

Graduate Research Posters

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. One-third of people diagnosed with COPD die of cardiovascular (CV) complications as opposed to pulmonary. Despite these odds, there are no therapies that mitigate this important health issue. Resveratrol, a naturally occurring antioxidant, improves CV health in other populations. However, there is currently no literature on resveratrol in patients with COPD. The purpose of this pilot study was to test if six weeks of resveratrol supplementation could improve CV health in patients with COPD. METHODS: A randomized, double-blind, pilot trial was completed in 8 patients with …

Impact Of Diet On Colorectal Cancer, Ashley Rosenberg Md, Mirinda Gromley Msph, Nicole Weighard Md, Juan Lu J Phd Mph Md

Graduate Research Posters

Background

Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide. Modifiable risk factors such as diet have been linked to the development of CRC but results of previous research have been inconsistent. We utilized the National Health and Nutrition Examination Survey (NHANES) to determine whether the consumption of dietary variables contributed to increased diagnosis of colorectal cancer.

Methods

Participants from NHANES 2015-2016 database aged 16 years or older, with available two-day dietary and CRC information were included. Study exposure included dietary consumptions (salt, cholesterol, sugar, fat, and carbohydrates); the outcome was self-reported CRC. Descriptive analysis was performed with …

A Pre-Transplant Blood-Based Lipid Signature For Prediction Of Antibody-Mediated Rejection In Kidney Transplant Patients, Monther Al Sultan, Daniel Contaifer Jr., Joshua Morriss, Suad Alshammari, Jeffrey Stern, Sindhura Bobba, Pamela Kimball, Anne King, Dhiren Kumar, Marlon Levy, Gaurav Gupta, Dayanjan Wijesinghe

Graduate Research Posters

Purpose. The aim of this study is to demonstrate the potential of the pre-transplant lipidome to predict post-transplant antibody-mediated rejection (AMR) in kidney transplant patients.

Methods. Patients were selected from a prospective observational cohort of a single-center adult kidney transplant center in the United States. The study included 16 kidney transplant patients who develop AMR within 2 years post-transplant and 29 stable control (SC) kidney transplant patients who did not develop AMR at any time within the post-transplant follow up. Selection of group differences on the day of transplant was determined by t-test analysis. Stepwise forward method was used to …

Richmond City Health District (Rchd), Bon Secours Richmond City Hospital (Rch), And Virginia Commonwealth Universities (Vcu) Department Of Health Behavior Policy (Hbp): Partnering With Community Health Workers (Chw) To Improve Community Health Outcomes And Reduce Emergency Department (Ed) Use, Anita M. Kumar, Mph, Stephanie Toney, Rn Bsn, Tamera Langhorne, Mba Chw, Bassan Dahman, Ph.D.

Graduate Research Posters

Background: Frequent ED users (5%) are sicker, poorer, not satisfied with the health system and cost 20% of total ED charges.

Objective: A pilot study of feasibility of partnering with CHW to improve health knowledge and outcomes and reduce ED use in low income community.

Methods: RCH ED utilizers were randomized to intervention and control groups. CHW contacted intervention group within 10 days of ED visit, surveyed about access to care, healthy living, and knowledge about chronic disease, and offered education, referrals to insurance and social and economic support. ED utilization and cost were recorded for all patients for 6 …

Does Ipe Improve Patient Safety?, Wendy Guzenski

Student Research Poster Presentations 2020

Interprofessional Education improves patient safety through collaboration and the common understand of patient care decisions and goals.

Street Medicine And Its Implications, Dylon Hess

Student Research Poster Presentations 2020

No abstract provided.

Has Planetree Patient-Centered Care Models Have A Positive Effects On Patient Outcomes?, Jacob Nagle

Student Research Poster Presentations 2020

No abstract provided.

Patent Foramen Ovale Closure Devices For Preventing Recurrent Cryptogenic Strokes, Megan Troutman

Student Research Poster Presentations 2020

This research looks at treatment options for patent foramen ovale (PFO) patient's with recurrent cryptogenic strokes. Surgical, drug therapy, and percutaneous closure options were explored to determine the safest, most effective forms of treatment for the patients. Several clinical trials were evaluated to show the success of the PFO closure device. A patients case was studied to understand why they were considered for the percutaneous treatment option. Several images and descriptions are provided to demonstrate the process of placing the device. A description of post procedure care and imaging was also provided to show how a physician deems the procedure …

Antibiotics Gone Viral: Reduce Their Use For Acute Bronchitis, Esther Steinhaus

Student Research Poster Presentations 2020

Antibiotic resistance has become a global health crisis. Providers contribute to this crisis by inappropriately prescribing antibiotics causing an increase in the number of drug resistant organisms. The leading cause of inappropriate antibiotic prescriptions in the primary care setting are upper respiratory tract infections, primarily acute bronchitis. The purpose of this evidence-based practice project is to determine if an educational program for primary care providers regarding appropriate use of antibiotics will reduce the number of antibiotic prescriptions issued for acute bronchitis. The following PICOT question was developed to guide this evidence-based practice project: “Among primary care providers treating adults in …

Freestanding "Er's" Come At A Cost, Krystal Whitenight

Student Research Poster Presentations 2020

No abstract provided.