Medicine and Health Sciences Commons^™

Development Of A Dendritic Cell Model To Unravel The Secrets Of Cards Toxin, Lizbeth Gomez

Posters - 2026

Dendritic cells (DCs) are derived from hematopoietic stem cells of the bone marrow. They are the most efficient antigen presenting cell, presenting antigens to T cells to initiate clonal expansion and differentiation of the T cells into memory and effector cells. Thus, activating the effector functions of T cells in cell-mediated and humoral immune responses (2). Community-acquired respiratory distress syndrome (CARDS) toxin is produced by Mycoplasma pneumoniae that causes acute and chronic lung infections (4). Dendritic cells play a key role in the immune response to respiratory mycoplasmas (3). However, the mechanism underlying in DC and CARDS toxin interactions are …

Signaling Response Of Epinephrine Treated Cards Toxin-Infected Thp-1 Macrophages, Trinity Martinez

Posters - 2026

Aspiration pneumonia is a common mild case of pneumonia, a disease where the lungs are inflamed and filled with fluid, compromising respiration and gas exchange. One common cause of mild pneumonia is bacterial infection via a pathogen known as Mycoplasma pneumoniae. M. pneumoniae causes a variety of respiratory illness- ranging from pharyngitis, tracheobronchitis, mild pneumonia- and in rare cases encephalitis. M. pneumoniae produces the CARDS toxin, which participates in ADP-ribosylation and vacuolization (Kannan et al., 2006)1. The CARDS toxin causes aspiration pneumonia by paralyzing the cilia that lines the respiratory tract. Epinephrine, or Adrenaline- is a hormone that is medically …

Effects Of Mycoplasma Pneumoniae Cards Toxin On Lung Fibroblast Function, Shuri Magdalene

Posters - 2026

Mycoplasma pneumoniae is a common respiratory pathogen whose virulence depends largely on the community-acquired respiratory distress syndrome (CARDS) toxin, a 591-amino-acid ADP-ribosylating protein¹. CARDS toxin induces immune responses²˒³, causes vacuolation in lung epithelial cells, and contributes to the inflammatory and pathological features of pneumonia. IMR-90 fibroblasts. IMR-90 cells are human fetal lung fibroblasts widely used to study responses to inflammatory signals, extracellular matrix production, and lung injury or repair. Rationale. Fibroblasts are key drivers of tissue remodeling and fibrosis during lung injury. Defining how CARDS toxin influences fibroblast programs in inflammation, cell-cycle control, and matrix remodeling²˒³ will clarify how M. …

Healthcare Systems & Policy Implications For Tele-Dentistry Policies On Access To Dental Care For Underserved Populations In The United States, Deeya Bhadresa

Posters - 2026

Access to dental care remains a significant public health challenge for people in rural and low-income communities. Tele dentistry has shown the ability to expand preventive services, improve care coordination, and reduce geographic barriers. However, inconsistent Medicaid coverage, limited infrastructure, and low provider participation restrict its impact. The main recommendation is standardizing Medicaid tele dentistry coverage and reimbursement across states to improve access and equity. Action is needed now to preserve post–COVID-19 telehealth gains and address persistent oral health disparities.

Evaluating The Effects Of Akt Knockdown And Everolimus Treatment On Ewing Sarcoma, Arisha Arif, Alfie Barcenez, Nicole Vanegas-Riddick

Posters - 2026

The purpose of this study is to use the gene AKT1, due to the interest in AKT1’s role in cancer cell proliferation, and the drug Everolimus, to determine if combined targeted therapy works as a more efficient therapeutic approach. We hypothesize that the knockdown of AKT1 will increase the sensitivity of Ewing sarcoma cells to Everolimus, resulting in reduced proliferation and/or survival compared to drug treatment alone. This would suggest that AKT1 normally protects cells from drug-induced stress. Ewing Sarcoma has been connected to chromosomal translocations and most common in pediatric patients. It is most often treated with chemotherapy and …

Impact Of Ashwagandha Treatment On Cytokine Production And Macrophage Differentiation Into Thp-1 Cells, Betsi Diaz Chavarin, Aditi Kumar

Posters - 2026

Inflammation is a critical biological response that enables the immune system to react to infections, injuries, or stressful situations. However, chronic or excessive inflammation can lead to tissue damage and contribute to a wide range of diseases, including neurodegenerative disorders, metabolic syndromes, and immune dysregulation. 3,4 Interleukin-1 beta (IL-1β) is a key pro-inflammatory cytokine that plays a central role in initiating and amplifying the immune response. 1,2 It is primarily produced by activated monocytes and macrophages in response to stimuli such as pathogens or stress signals. In addition, IL-1β acts on the hypothalamus to induce fever, which creates an environment …

Sirna Knockdown Of Rptor Alters Gene Expression In Ewing Sarcoma Cells, Sergio Cipriano, David Leavitt, Michael Oliva, Liam Valdez

Posters - 2026

Ewing sarcoma is a highly aggressive cancer that primarily affects children and young adults. Although treatment options exist, many patients do not respond effectively, showing the need for improved targeted therapies¹. RPTOR is a key in mTORC1 complex which regulates cell growth, proliferation, and survival². LY2874455 is a selective pan-FGFR inhibitor that targets growth factor signaling pathways involved in tumor progression³, and FGFR signaling interacts with pathways such as mTOR, making it a potential target for combination therapies. We hypothesized that silencing RPTOR in Ewing sarcoma cells would disrupt mTOR signaling and alter expression of genes linked to cell survival …

Healthcare Systems & Policy Implications For The Impact Of State Medicaid Reimbursement Rates On Access To Primary Care Services In Rural Communities: Turning Knowledge Into Action, Miriam Martinez

Posters - 2026

• Where a child lives can determine whether they receive care or go without it. • Access to primary care is essential for prevention, early diagnosis, and treatment, but rural areas face persistent challenges such as provider shortages and geographic isolation. • Medicaid serves as the primary source of health coverage for low-income children; however, reimbursement rates vary by state and are often lower than other forms of insurance. • This study examines how Medicaid reimbursement policy contributes to disparities in access to care for rural children and reflects broader structural inequalities within the healthcare system.

The Cost Of Affordable Healthcare: How Brazil's Sus And Generic Drug Strtegy Produce Structural Inequality And Challenge Global Pharmaceutical Rules, Elena Kössler

Posters - 2026

Affordable healthcare is often seen as a major social achievement, but maintaining low costs involves important trade-offs. Brazil’s Unified Health System (SUS) provides universal healthcare and relies heavily on generic medicines to expand access. This raises a central question: how can a system reduce the cost of healthcare while simultaneously generating new forms of inequality and tension within global pharmaceutical markets? This paper argues that Brazil’s cost-reduction strategy, particularly its reliance on generic medicines, improves affordability but also produces structural trade-offs between equitable access, quality of care, and incentives for pharmaceutical innovation.

Gene Expression And Apoptotic Responses To Panobinostat Treatment And Yap Knockdown In Ewing Sarcoma Cells, Luna Collazo-Garcia, Alejandra Favela Santos, Madeline Torres-Salazar, Isabella Toscano

Posters - 2026

Ewing sarcoma is an aggressive pediatric cancer driven by abnormal gene expression caused by the EWS-FLI1 fusion protein

Usually treated with intensive treatments such as chemotherapy and radiation

Outcomes remain poor for metastatic disease, highlighting the need for new therapeutic strategies

The Hippo signaling pathway regulates cell proliferation and survival through the transcriptional co-activator YAP1

Une Com Spring Research Bulletin May 2026, Une Com Research & Scholarship

Osteopathic Student Research Symposia

Bulletin including abstracts from the University of New England College of Osteopathic Medicine’s 2026 inaugural Spring Research Update and Lightning Talk event.

Initial Results Of A Structured Coaching Program For Academic Promotion Preparation, Jacqueline Hill, Christine Sullivan, Tyler Smith, Margaret Gibson, Valerica Mateescu, Wendell K. Clarkston

Posters

Introduction: Applying for academic promotion can be a confusing and arduous process, often with little guidance to assure a successful experience, especially for junior faculty located at affiliate hospitals. Goals: We present initial results of a structured university mentorship program to prepare faculty to apply for academic promotion. Methods: Program was designed as a small working group of 5 structured sessions over a 9-month period where participants were coached by senior faculty from 3 university affiliate hospitals. Program culminated in the completion of an academic promotion application. Results: Since launch in 2019, we have completed 4 program cohorts and paused …

Library & Knowledge Services Newsletter - Spring 2026, Maria Roman

Library Newsletters

Library & Knowledge Services Newsletter - Spring 2026

Optimizing Makeup Application Techniques For Women With Tenodesis: Adaptations And Ergonomic Solutions, Ashley J. Medina, Wendy Tremaine, Lee Ann Hoffman

Spring 2026 OTD Capstone Symposium

To enhance independence in makeup application for women utilizing a tenodesis grasp, Ashley Medina, OTS, in collaboration with Able Faith, Inc., developed and presented a capstone poster outlining a targeted program of adaptive strategies and ergonomic solutions. This program was designed to address the unique functional challenges experienced by women with spinal cord injuries (SCIs) while promoting autonomy and confidence in daily self-care routines.

The experience objectives included: (1) identifying existing adaptive equipment that supports individuals with SCIs in completing makeup application tasks; (2) examining and understanding the roles of interdisciplinary team members working with individuals with SCI in comparison …

Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Wednesday, April 1, 2026, Wright State University

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Celebration of Student Research, Scholarship & Creative Activities on April 1, 2026.

Start With What They Know: Using Motivational Interviewing To Create A Cooking Class, A Culinary Intervention For Teens (Autistic And Non-Autistic), Gwendolyn S. Tedder

LEND Trainee Presentations

Autistic teens are at greater risk for having heart disease and diabetes as adults. Food particularity, sensory issues, fixed mindset, and anxiety over trying new things can slow down their interest in preparing food for themselves. Nurturing basic cooking skills and gently encouraging trying new foods would provide more nutritional options to teens as they move into adulthood. A cooking class preceded by Motivational Interviewing (MI) developed further interest in preparing food afterward in teens, both autistic and non-autistic, and in trying new foods for autistic teens with food concerns.

Sharksrx Newsletter Spring 2026, Nova Southeastern University

NSU Sharks Rx

No abstract provided.

Growing South Dakota (Spring 2026), College Of Agriculture, Food, And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 National heritage, statewide research, local impact
[Page] 7 About the South Dakota Agricultural Experiment Stations
[Page] 14 Managing the mooo-ment: How SDSU researchers are looking to improve cow health during the Transition Period
[Page] 18 Discovering strength in science: How education through undergraduate research prepares students for the future
[Page] 20 From India to Brookings: One grad student’s path to make a world of difference in virology
[Page] 22 Solving a billion-dollar problem: Identifying disease-resistent wheat genes
[Page] 24 Unlocking manure’s potential: SDSU leads multistate study on the power of swine manure in growing better crops
[Page] 28 …

Something In The Air? Uncovering The Air Quality Of St. Mary's University, Isaiah Charles, Keagan Farrell, Antonio Martinez, Andrea Realyvasquez, Kelly Swyers

Presentations - 2026

What is air quality?

Measurement of how clean or polluted the air is in a certain area. The Environmental Protection Agency uses Air Quality Index (AQI), a scale that describes the quality of air. The six major pollutants measured are: •ground- level ozone •particulate matter •carbon monoxide •sulfur dioxide •nitrogen dioxide •lead   Impacts of air pollution
•Acid rain •Climate change •Damage to plants and crops •Loss of biodiversity
•Respiratory illnesses •Cardiovascular damage •Premature death •Coughing and asthma

Cure Sound Project: Study In Silence?, Quezia Abrao, Deeya Bhadresa, Elisa Castro, Fiona Coulbourne, Carlos Flores, Lizzeth Holguin, Lazarus Maldonado, Jeremy Mares, Andrew Martini, Nicole Matthews, Katherine Montero, Mariana Reyes, Jacob Rodriguez, Julieta Ruiz, Eliana Sanchez, Gabriela Varela

Posters - 2026

Difference in sound levels in study areas across campus can affect students’ ability to work and learn efficiently 1.

According to the WHO, safe sound levels are measured to be around 70dB 2. Some study areas on campus experience sound levels exceeding the safe threshold. Unsafe sound levels are considered to be at or above 85dB 3. These unsafe and excessive noise levels negatively affect a student’s ability to concentrate and work efficiently which correlates to a decrease in class performance, attention deficits, and stress 4.

This study aims to get a base-line measurement of dB levels in common study …

Neurophenomenology: A Research Method Combining Neuroscience And Philosophy, Jonas Lokensgard

Posters - 2026

Neurophenomenology – Cognitive Sciences + Phenomenology Phenomenology – the study of consciousness (basically just how you experience things) Cognitive Sciences – The study of the functional processes of the mind, and the operations of the brain that enable these processes to be performed. (“Cognitive Science” 2004)

Analyzing The Effect Of Melatonin On B Cells' Expression Of Cd36, Caitlyn Pinaga, Gabriella Galdeano, Nayi Gonzalez, Emma Welsch

Posters - 2026

• B cells specifically target pathogens and proliferate to make a plasma cell and secrete antibodies when stimulated. They use glucose as a main energy source but can also use fatty acids. • CD36 is a glycoprotein involved in the transportation and metabolism of fatty acids. • B cells express CD36 in unusually high levels in autoimmune patients. It is unknown as to how this occurs. • Melatonin is a hormone produced in the pineal gland, commonly known for its function in regulating the circadian rhythm. • Melatonin is also known as a master cell regulator and is believed to …

Obesity In The Rio Grande Valley: Applying An Evidence-Based Public Health Approach, Erika Pineda-Horta

Posters - 2026

What structural and social determinants drive elevated adult obesity rates in the Rio Grande Valley, and what evidence-based interventions can reduce adult obesity prevalence in Hidalgo County by 5% by 2030?

Objective: This study applies an EBPH framework to (1) characterize the burden and structural determinants of adult obesity in the RGV, and (2) propose a culturally responsive, evidence-based intervention targeting adults aged 18+ in Hidalgo County.

Adult obesity is clinically defined as a Body Mass Index (BMI) ≥30 kg/m² in adults aged 18 and older (CDC, 2022). It is a chronic, multifactorial non-communicable disease shaped by structural, social, and …

Bridging Cultures: Developing A Culturally Responsive Educational Website For Pediatric Service Providers, Aimun Aziz, Wendy Tremaine

Spring 2026 OTD Capstone Symposium

The increasing cultural diversity of the pediatric population in the United States highlights the need for culturally responsive, family-centered care. However, many providers report limited training and practical resources to support the integration of cultural humility into clinical practice. This capstone project aimed to develop and evaluate an evidence-based educational website to support pediatric service providers in delivering culturally responsive care.

A program development framework was used, incorporating family needs assessments, pre- and post-intervention surveys of pediatric therapy staff, and thematic analysis of key factors related to communication, trust, and provider preparedness. Community field visits with diverse populations informed the …

Ready, Set, Play! Empowering Caregivers Through Adaptive Playground Resources, Makenna Thigpen, Angela Blackwell, Brianne Harryman

Spring 2026 OTD Capstone Symposium

This doctoral capstone project addressed the need for accessible, caregiver-friendly education to support inclusive play opportunities for children of diverse abilities. Guided by occupational therapy frameworks emphasizing participation, environmental supports, and family-centered care, this project involved collaboration with the local Parks and Recreation Department to better understand community needs and existing inclusive playground resources. Through this partnership, the project supported efforts to promote awareness and accessibility of inclusive play spaces within the community.

As part of the project, educational video resources were developed to increase caregiver knowledge of inclusive playground equipment, play strategies, and environmental modifications. Content focused on promoting …

Enhancing Student Engagement In Leadership And Advocacy, Rosanoemi A. Mejia, Jazminne Orozco Arteaga

Spring 2026 OTD Capstone Symposium

Occupational therapy has a unique capacity to foster social change and occupational justice. Leadership and advocacy are essential components of the daily academic practice for occupational therapists. However, leadership development within the field is largely socially driven, and students often lack access to structured, mentored pathways that would empower them to speak up and engage in advocacy. This capstone project aimed to fill this gap by addressing the shortage of coordinated mentorship and leadership development opportunities, which hinder advocacy efforts and professional growth. The study employed a mixed-methods approach, involving occupational therapy students in quantitative Likert-scale surveys and qualitative semi-structured …

Regional Inequalities In Healthcare Access And Capacity In Brazil, Elena Kossler

Posters - 2026

The Brazilian health system is one of the largest and most comprehensive universal public health systems, fully funded by the government.

Detecting Cancer Genes Using Graph Neural Networks, Marvin Masabo Nkaka

Posters - 2026

• Cancer survival prediction is challenging due to the complexity of genomic data and limited samples especially for rarer cancer types. • To address this challenge, we developed an Artificial Neural Network (ANN) model for survival analysis using RNA-sequencing gene expression data from The Cancer Genome Atlas (TCGA). • Moreover, a key concept we investigate was how transfer learning enhanced our model’s performance especially for rarer cancer types difficult to perform accurate survival analysis due to their limited samples.

Clinical And Non-Clinical Factors Associated With Early Discharge In Pediatric Non-Trauma Patients Transported By Rotor Wing, Jordon Mitzelfelt, Lisa Pruitt, Amy Papa, Ashley K. Sherman, David Juang, Sarah Brunner, Asdis Finnsdottir Wagner, Jennifer Flint

Posters

Objective: Helicopter emergency medical services (HEMS) are crucial for transporting critically ill children to definitive care, however, rising costs and relative risks of this type of transportation necessitate careful evaluation of potential over-utilization. Current literature primarily focuses on pediatric trauma patients, leaving a significant gap in data regarding non-trauma pediatric HEMS transports and the influence of non-clinical factors such as referral hospital distance, resources, and capabilities on transport decisions. This study aims to address these gaps by examining non-trauma pediatric HEMS patients and identifying associated clinical and non-clinical factors related to early hospital discharge (< 24 hours). Methods: This retrospective, single-center study includes pediatric patients with medical and non-trauma surgical diagnoses transported by HEMS between April 1, 2021 and March 31, 2024. Clinical data were extracted from transport team records and the hospital’s electronic health records. Analyses were performed to identify factors associated with discharge within 24 hours of admission. To identify predictors of early discharge, we analyzed clinical factors including chief complaint, pre-transport vascular access, transport crew interventions (medication administration and procedures), respiratory assistance, and Pediatric Age-Adjusted Shock Index (SIPA) scores. Additionally, we examined the impact of the initial admit unit, and medical support required within the first 24 hours of hospitalization. Non-clinical predictors included the referring hospital’s status (critical access and/or rural designation) and the time of transport. Results: A total of 568 patients were transported by HEMS, of whom 88 (15%) were discharged within 24 hours. Patients in the early discharge group were more likely to present with neurologic chief complaints (40%), whereas those remaining hospitalized beyond 24 hours more frequently presented with respiratory complaints (40%). Normal SIPA scores both prior to and at the conclusion of transport were significantly associated with early discharge (p=0.012 and p=0.011, respectively). Furthermore, patients requiring no medications or respiratory assistance during transport, or no respiratory support within the first 24 hours of admission, were significantly more likely to be discharged early (p< 0.001). Notably, all patients with central access prior to transport remained admitted for more than 24 hours (p=0.004). Regarding non-clinical factors, patients transported from designated rural hospitals were more likely to experience early discharge (p< 0.001). Conclusion: These results characterize the pediatric non-trauma HEMS population and identify key predictors of early hospital discharge. This data is essential for developing standardized dispatch criteria to mitigate over-utilization and ensure high-acuity transport is reserved for the most appropriate patients.

Does Variation In Systemic Steroid Use Impact Outcomes In Preschoolers Hospitalized With Viral Respiratory Tract Infection?, Smit Shah, Kathryn Kyler, Matt Hall, Jessica Markham

Posters

Background: Systemic corticosteroids (SCS) are a cornerstone of treatment for acute asthma exacerbation. However, the role of SCS in preschool-aged children hospitalized with viral respiratory tract infection (vRTI), including viral induced wheezing, remains uncertain. Clinical trials have reported conflicting results about the benefits of SCS in this population. Objectives: To evaluate hospital-level variation in inpatient management of preschool-aged children admitted with vRTI and to compare clinical and utilization outcomes based on hospital-level SCS use. Methods: We conducted a retrospective cohort study of children aged 24-59 months admitted to US children’s hospitals with vRTI from July 2022-July 2024 using the Pediatric …