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Full-Text Articles in Medicine and Health Sciences

Probiotic Therapy For The Treatment And Prevention Of Bacterial Vaginosis, Chelsea Scheil Apr 2024

Probiotic Therapy For The Treatment And Prevention Of Bacterial Vaginosis, Chelsea Scheil

Physician Assistant Scholarly Project Posters

Bacterial vaginosis (BV) is a common presenting complaint in healthcare, and patients often experience recurrences at a frustrating rate. The mainstay of current treatment is antibiotic therapy, either via oral or vaginal route. When recurrences occur, stronger antibiotics are often employed. This current method of treatment does not address an underlying component that impacts infection recurrence and rate of recurrence- the patient’s baseline vaginal microbiome and the healthy bacteria that support it. To investigate the use of probiotics in bacterial vaginosis treatment, a comprehensive literature review was completed using databases PubMed and Embase. The results of this literature review confirm …


Minimally Invasive Therapies In The Treatment Of Arthropathy, Steven Bateman Apr 2024

Minimally Invasive Therapies In The Treatment Of Arthropathy, Steven Bateman

Physician Assistant Scholarly Project Posters

This literature review explores the efficacy of minimally invasive therapies that precede and delay surgical intervention in adult patients experiencing functional limitations and pain in major joints. The effectiveness of physical therapy and injections such as corticosteroids, hyaluronic acid, platelet-rich plasma, and mesenchymal stem cells (MSC) was evaluated. A comprehensive search of PubMed utilizing MeSH terms yielded 114 relevant studies, which were screened based on inclusion criteria of human studies published within the past five years. Keywords included mesenchymal stem cells, stem cells, mesenchymal, arthroplasty, and joints. Producing few results, inclusion criteria were later expanded to include studies within the …


A Manualized Occupational Therapy Communication Skills Intervention For Veterans With Posttraumatic Stress Disorder, Kiara Ainsworth, Steven M. Gerardi Apr 2024

A Manualized Occupational Therapy Communication Skills Intervention For Veterans With Posttraumatic Stress Disorder, Kiara Ainsworth, Steven M. Gerardi

Spring 2024 Virtual OTD Capstone Symposium

Post-traumatic stress disorder (PTSD) affects many individual's participation in daily activities. There is a lack of research in the area of occupational therapy (OT) treatment for veterans with PTSD. However, there has been an expressed need in the literature for a developed intervention for veterans with PTSD that includes communication skills as a component. To date, a manualized communication skills OT intervention for veterans with PTSD has not been created. The purpose of this paper was to develop a resource tool for occupational therapists to utilize as an intervention when treating veterans with PTSD using the framework of the Model …


A Guidebook For Latina Breast Cancer Survivors & Occupational Therapy Practitioners, Abigail Hernandez, Leslie Khan-Farooqi, Mary Ann Smith Apr 2024

A Guidebook For Latina Breast Cancer Survivors & Occupational Therapy Practitioners, Abigail Hernandez, Leslie Khan-Farooqi, Mary Ann Smith

Spring 2024 Virtual OTD Capstone Symposium

Many Latina women diagnosed with breast cancer face psychosocial challenges and do not have access or the necessary resources to assist them with these challenges which may lead to decreased quality of life. This study is designed to address the most common psychosocial issues associated with breast cancer to assist Latina women as well as occupational therapy practitioners.


Colors Of Connection: A Manual For Cultivating Social And Emotional Skills In Children With Disabilities Through Creative Arts, Allie Hertaus, Angela Labrie Blackwell Phd, Otr, Haleigh Freeman Otd, Otr/L Apr 2024

Colors Of Connection: A Manual For Cultivating Social And Emotional Skills In Children With Disabilities Through Creative Arts, Allie Hertaus, Angela Labrie Blackwell Phd, Otr, Haleigh Freeman Otd, Otr/L

Spring 2024 Virtual OTD Capstone Symposium

Children with disabilities (CWD) are experiencing occupational deprivation due to limited involvement in extracurricular activities. This deprivation impedes their development of social-emotional skills. In attempt to mitigate this deprivation, the OTD student created and implemented Colors of Connection, a creative arts based, social and emotional learning program into an already existing after school program for CWD.


Play Over Talk: A Toolkit For Educators On Adverse Childhood Experiences, Brianna Gallegos, Mary Ann Smith, Cat Daniel Apr 2024

Play Over Talk: A Toolkit For Educators On Adverse Childhood Experiences, Brianna Gallegos, Mary Ann Smith, Cat Daniel

Spring 2024 Virtual OTD Capstone Symposium

Adverse childhood experiences (ACEs) are traumatic experiences that can lead to negative, lasting effects on the health and well-being of the child. Students who have ACEs are more likely to struggle in school, have difficulty paying attention, lack self-regulation skills, and struggle to control their emotions and behaviors. Teachers and school staff may not recognize or know how to support students who have adverse childhood experiences (ACEs) which can impact the child’s occupational role as a student. To date, a resource for school staff with information on ACEs, interventions, and strategies has not been created. The purpose of this project …


Management Of Sensory Processing Challenges In The Classroom: An Educational Video Series For Teachers., Jasmine Guerrero, Steven M. Gerardi Apr 2024

Management Of Sensory Processing Challenges In The Classroom: An Educational Video Series For Teachers., Jasmine Guerrero, Steven M. Gerardi

Spring 2024 Virtual OTD Capstone Symposium

An educational video series for teachers on sensory processing and how to manage students with sensory processing challenges in the classroom. The video series includes evidence-based supports and strategies that may be utilized in the classroom to improve students' occupational performance.


Occupational Engagement In Recreational Sports For The Deaf And Hard Of Hearing: An Employee Guidebook, Colleen Mcerlean, Mary Ann Smith, Christopher Ebner Apr 2024

Occupational Engagement In Recreational Sports For The Deaf And Hard Of Hearing: An Employee Guidebook, Colleen Mcerlean, Mary Ann Smith, Christopher Ebner

Spring 2024 Virtual OTD Capstone Symposium

An employee guidebook to help increase occupational engagement within recreational sports for the Deaf and Hard of Hearing population in the Austin, TX area.


Self-Regulation And Sensory Processing Education Program For Educators, Julianne Mendivil, Tina G. Bhakta, Angela Blackwell Apr 2024

Self-Regulation And Sensory Processing Education Program For Educators, Julianne Mendivil, Tina G. Bhakta, Angela Blackwell

Spring 2024 Virtual OTD Capstone Symposium

Children with low self-regulation skills may face many challenges in the classroom environment that can impact their performance in school-based activities. As teachers play a vital role in the development of young children, this educational program aims to improve teacher competence (knowledge, skills, and attitudes) in applying sensory processing and self-regulating concepts to the school environment.


The Transition To Adulthood For High School Students With Special Needs, Athena Hays, Mary Jan Greer, Jinna Danser Apr 2024

The Transition To Adulthood For High School Students With Special Needs, Athena Hays, Mary Jan Greer, Jinna Danser

Spring 2024 Virtual OTD Capstone Symposium

The reason for many special needs students not engaging in occupations after high school is because many guardians have not had to navigate this type of transition before and are not provided enough education on what these opportunities include before their students graduate. Many students with special needs do not optimize their engagement in the community because guardians are not being provided with education on post-graduate opportunities.

The purpose of my Doctoral Capstone Project is to develop an educational transition service program for special needs students as well as guardians and teachers of these students preparing for high school graduation …


Play Is A Way Of Life: Play-Based Program For Parents Of Young Children (Ages Two To Five Years Old), Lauren Purdom, Angela Labrie Blackwell, Amanda Perdue Owen Apr 2024

Play Is A Way Of Life: Play-Based Program For Parents Of Young Children (Ages Two To Five Years Old), Lauren Purdom, Angela Labrie Blackwell, Amanda Perdue Owen

Spring 2024 Virtual OTD Capstone Symposium

This play-based program was created for parents of young children (ages two to five years old) and is accessible through a website called "Play is a Way of Life". Within this program it includes, educational material on the differences between active and passive play and recommendations for each type of play that children in this age group should participate in each day. It also includes a 6-week program with a variety of active play activities that target specific skills that children (ages two to five years old) should participate in for their overall development.


The Ci-Asd Program: Implementation Of Contextual Interventions For Autism Spectrum Disorder (Ci-Asd) With Latino Families (Preliminary Report), Gabriel Gonzalez, Erik Pérez, Angela Blackwell Apr 2024

The Ci-Asd Program: Implementation Of Contextual Interventions For Autism Spectrum Disorder (Ci-Asd) With Latino Families (Preliminary Report), Gabriel Gonzalez, Erik Pérez, Angela Blackwell

Spring 2024 Virtual OTD Capstone Symposium

Children diagnosed with Autism Spectrum Disorder (ASD) experience sensory processing differences that affect their participation in daily activities and routines. Autism affects an estimated 1 in 36 children in the U.S. However, Latino children are diagnosed two years later than white children. Latino families still have the greatest disparities in accessing ASD resources throughout the U.S. compared to white families. The lack of ASD services and resources led to decreased parental self-efficacy, quality of life, and increased child behavioral problems.

Contextual Interventions Adapted for Autism Spectrum Disorder (CI-ASD) are an emerging intervention for occupational therapy (OT) practitioners. Recent literature shows …


Intouch Week Of April 1, 2024, New York Medical College Apr 2024

The Scoop, Vol. 11 Issue 1, April 2024, Health Sciences Library Apr 2024

The Scoop, Vol. 11 Issue 1, April 2024, Health Sciences Library

Volume 11

Latest news and updates from the Health Sciences Library in our monthly newsletter for April 2024.


Finger Contracture Relief Sensorized Splint, Katia Campos, Alfonso Gonzalez, Olivia Rojas Apr 2024

Finger Contracture Relief Sensorized Splint, Katia Campos, Alfonso Gonzalez, Olivia Rojas

Posters - 2024

Hand traumas may result from an accident, a burn, or even something far more common like a jammed finger. Due to the pain, the hand is immobilized and this lack of movement, in addition to the healing processes, can lead to a deformity. The specific deformity addressed in this project is a Proximal Interphalangeal Joint Flexion Contracture, which is when the middle knuckles of the fingers are stuck in a flexed position. Contractions can occur after trauma or certain illnesses. It is the shortening of muscles, tendons, skin, and nearby soft tissues that causes the joints to become very stiff. …


The Quantification Of Essential Oils And Bixin In Annatoo Seeds, Alycia C. Johnson, Susan Oxley Apr 2024

The Quantification Of Essential Oils And Bixin In Annatoo Seeds, Alycia C. Johnson, Susan Oxley

Posters - 2024

Bixa orellana (also known as annatto or achiote) originates from South America but it can be found nearly everywhere in the world. The seeds of this species make for an excellent natural coloring. It is applied to makeup, food, and textiles; some of the biggest commercial industries.1 Of the 50+ phytochemicals identified, there are a large number of essential oils and other compounds that have been shown to have beneficial properties. Four of these compounds will be used to determine which traditional processing method results in the biggest loss of phytochemicals. Annatto is often either fried, left whole, or powdered …


Improving Frequency Of Peer Review Of Abnormal Genital Exam Findings In Patients Undergoing Sexual Abuse Evaluation, Lyndsey Hultman, Terra N. Frazier, Jennifer Hansen Apr 2024

Improving Frequency Of Peer Review Of Abnormal Genital Exam Findings In Patients Undergoing Sexual Abuse Evaluation, Lyndsey Hultman, Terra N. Frazier, Jennifer Hansen

Presentations

Background/Objectives: 2023 Child Advocacy Center (CAC) accreditation standards require that “all medical professionals providing services to CAC clients must demonstrate that 100% of all findings deemed abnormal or “diagnostic” of trauma from sexual abuse have undergone expert review by an advanced medical consultant”. Prior to program implementation, scheduled Case Review occurred among the authors’ institution child abuse pediatricians (CAPs), but typical practice was to review cases upon CAP request. The authors’ institution faced practice standard implementation barriers of high case volumes and collaboration with multiple different CACs. Our primary aim was to increase peer review of abnormal exams from a …


Antimicrobial Duration Stewardship Project: A Qi Approach, Joshua Saucedo, Rana El Feghaly, Amanda Nedved, Leslie Hueschen, Marsha Dannenburg, Tanis Stewart, Patty Philips, Jennifer Floyd Apr 2024

Antimicrobial Duration Stewardship Project: A Qi Approach, Joshua Saucedo, Rana El Feghaly, Amanda Nedved, Leslie Hueschen, Marsha Dannenburg, Tanis Stewart, Patty Philips, Jennifer Floyd

Presentations

A QI project aimed at increasing the percentage of children discharged home from the emergency department with a diagnosis of community acquired pneumonia (CAP) or acute bacterial rhinosinusitis (ABRS) treated with an optimal antibiotic duration (5 days or less for CAP, 7 days or less for ABRS) from 22% to 70% by July 2025. Additionally, assess for differences in care based on demographic and socioeconomic factors such as the area deprivation index. National guidelines and CMH clinical pathways recommend short antibiotic durations (5-7 days) for most infections (5 days for community acquired pneumonia, 5-7 days for acute bacterial rhinosinusitis). At …


An Increased Failure Rate Of Asparaginase Desensitization With Calaspargase Pegol, Jillian Fry, Erin M. Guest, Keith J. August Apr 2024

An Increased Failure Rate Of Asparaginase Desensitization With Calaspargase Pegol, Jillian Fry, Erin M. Guest, Keith J. August

Posters

Background: In late 2022, pegaspargase (SS-PEG) became unavailable to patients younger than 22 years in the United States, leaving calaspargase pegol (SC-PEG) as the only available long-acting asparaginase formulation. SC-PEG has been compared to SS-PEG in two randomized, pediatric clinical trials and found to have similar rates of adverse events with comparable rates of event-free survival. Our institution uses a desensitization protocol for patients who experience a hypersensitivity reaction to asparaginase. Here we review our experience with desensitization since the transition to SC-PEG from SS-PEG. Objectives: To compare the rate of hypersensitivity reactions, success of desensitization protocols, and need for …


Diagnosis Of Mosaic Rasopathy In A Child With Rhabdomyosarcoma, Meagan Vacek, Paige Johnson, Midhat S. Farooqi, Kristi M. Canty, Dihong Zhou, Brendan Lanpher, Wendy Allen-Rhoades, Erin M. Guest Apr 2024

Diagnosis Of Mosaic Rasopathy In A Child With Rhabdomyosarcoma, Meagan Vacek, Paige Johnson, Midhat S. Farooqi, Kristi M. Canty, Dihong Zhou, Brendan Lanpher, Wendy Allen-Rhoades, Erin M. Guest

Posters

Background: Phacomatosis pigmentokeratotica (PPK) is a subtype of epidermal nevus syndrome characterized by the co-existence of a sebaceous nevus and a speckled lentiginous nevus and described in approximately 30 cases in literature. PPK is now recognized as a mosaic RASopathy due a postzygotic mutation in the Ras-Raf-MEK-ERK pathway. RAS variants are also known to contribute to tumorigenesis, in some pediatric cancers, including rhabdomyosarcoma. Objective: Describe the presentation and evaluation of a child with pelvic rhabdomyosarcoma and evolving skin lesions found to have a rare mosaic-RASopathy. Design/Method: Case Report Results: The patient is a former 32-week premature female who presented to …


Anesthetic And Multidisciplinary Management Of A 2-Staged Liver Transplant​, Kasey Brooks, Lisa Conley, Brandon Layton Apr 2024

Anesthetic And Multidisciplinary Management Of A 2-Staged Liver Transplant​, Kasey Brooks, Lisa Conley, Brandon Layton

Posters

We present a case of a 2 staged liver transplant on a 12-month-old 8kg male with newly diagnosed mitochondrial depletion syndrome causing acute liver failure, refractory lactic acidosis, and cardiopulmonary collapse requiring ECMO. The patient’s past medical history at the time of presentation included history of prematurity at 32 weeks, developmental delay, and a brother with an undiagnosed pancreatic disorder. The patient was brought in by parents to the emergency department with a cough, minimal PO intake for 5 days, and increased fatigue who was found to be URI positive. Initial labs were concerning for anemia, elevated bilirubin, elevated AST/ALT, …


Early Cholestasis And Vitamin K Deficiency Secondary To Biliary Atresia Presenting As Coagulopathy And Thymic Hemorrhage, Abbey Elsbernd, Lauren Amos Md Apr 2024

Early Cholestasis And Vitamin K Deficiency Secondary To Biliary Atresia Presenting As Coagulopathy And Thymic Hemorrhage, Abbey Elsbernd, Lauren Amos Md

Posters

Background Bleeding and progressive coagulopathy are established symptoms of early cholestasis, including extrahepatic biliary atresia. We present a patient with bleeding secondary to vitamin K deficiency and cholestasis-induced fat malabsorption with unusual presentation of mediastinal mass. Objective Describe a case of late-onset vitamin K deficiency and cholestasis ¬¬presenting as jaundice and coagulopathy with associated bleeding into thymic structures Design/Method Case report Results A 4-week-old term male infant was brought to the ED with fussiness and bruising. Prior to presentation, he was afebrile and followed regularly with his primary care provider for jaundice below phototherapy thresholds. Infant received vitamin K at …


Single Center Retrospective Comparison Of Bivalirudin And Heparin For Therapeutic Anticoagulation In Pediatric Patients, Clayton Habiger, Shannon L. Carpenter Apr 2024

Single Center Retrospective Comparison Of Bivalirudin And Heparin For Therapeutic Anticoagulation In Pediatric Patients, Clayton Habiger, Shannon L. Carpenter

Posters

Background: The pharmacological choice for continuous anticoagulation therapy in pediatric patients has classically been unfractionated heparin. However, with heparin there are risks of treatment resistance in pediatrics given differences in developmental hemostasis, and contemporary medications such as bivalirudin offer a valuable alternative. Bivalirudin binds to thrombin and has shown encouraging results compared to heparin in pediatric patients receiving ECMO, but no comparison has been made in patients receiving therapeutic anticoagulation. Three years ago, Children’s Mercy Pediatric Hematology department encouraged bivalirudin use over heparin use for therapeutic anticoagulation requiring a continuous infusion. Objectives: Compare clinical and laboratory outcomes in patients receiving …


Transition Skills Lab: A Telehealth Intervention For Improving Healthcare Transition In Youth With Special Health Care Needs, Angela Combs Ma, Alaina Linafelter, Jordan Sevart, Michele H. Maddux Apr 2024

Transition Skills Lab: A Telehealth Intervention For Improving Healthcare Transition In Youth With Special Health Care Needs, Angela Combs Ma, Alaina Linafelter, Jordan Sevart, Michele H. Maddux

Posters

Introduction: Few interventions exist to provide hands-on practice of key health management tasks to youth with special health care needs (YSHCN). The Transition Skills Lab was adapted from Jerlym Porter’s work and piloted as a virtual intervention in YSHCN. Methods: Sixteen young adults participated in the virtual Transition Skills Lab, during which they practiced three key patient competencies pertaining to health care tasks: reading an insurance card, reading a pill bottle label, and scheduling an initial visit with an adult doctor. Participants were then asked to rate their confidence on skills taught within the intervention on a four-point scale from …


Congenital Heart Defects And Autism: Understanding The Breakdown Of Associated Risk Factors In A Clinically Referred Sample, Elizabeth Raines, Amanda Strasser, Amanda Manderfeld, Paul Glasier, Elizabeth J. Willen Apr 2024

Congenital Heart Defects And Autism: Understanding The Breakdown Of Associated Risk Factors In A Clinically Referred Sample, Elizabeth Raines, Amanda Strasser, Amanda Manderfeld, Paul Glasier, Elizabeth J. Willen

Posters

Background: Children with Congenital Heart Disease (CHD) have higher odds of developing social difficulties and/or an Autism Spectrum Disorder (AuSD) than the general population (i.e., ~10% vs. ~1%). However, there is a paucity of nuanced understanding of specific drivers of the increased rates of AuSD in extant literature. The purpose of this study is to identify the rates of co-occurring cardiac, neurological, and genetic conditions to better understand associated risk factors in a patient sample from a medium-size children’s hospital. Methods: Our population includes a clinically referred sample of children (i.e., medical history of CHD and neurodevelopmental risk) under 18 …


Parents’ Perception Of An Intensive Interdisciplinary Pain Treatment For Amplified Pain Syndrome, Jacqueline Pabis Phd, Sabrina Ung, Jenny Scheurich, Dustin Wallace Phd Apr 2024

Parents’ Perception Of An Intensive Interdisciplinary Pain Treatment For Amplified Pain Syndrome, Jacqueline Pabis Phd, Sabrina Ung, Jenny Scheurich, Dustin Wallace Phd

Posters

Introduction: Intensive interdisciplinary pain treatment (IIPT) is an effective treatment for youth impaired by chronic pain (Claus et al., 2022). IIPT programs incorporate parents in treatment, as parental distress has been found to impact health and functioning in youth with chronic pain. Research has suggested parent satisfaction may be related to increased child adherence, and in turn, reduced pain (Gorodzinsky et al., 2012). There is limited research on parental satisfaction with IIPT and the role of parent-provider communication. Method: Parents (n=99) of children in an IIPT program completed questionnaires related to treatment satisfaction, parent-provider communication (e.g., provider listened carefully, provider …


2024 Spring Vol. 41 No. 1, Alumni Affairs School Of Medicine Apr 2024

2024 Spring Vol. 41 No. 1, Alumni Affairs School Of Medicine

Medicinews

No abstract provided.


Isn’T It A Partnership?: Physician Partner Life Satisfaction, Elias Ciudad, Lori Boies Apr 2024

Isn’T It A Partnership?: Physician Partner Life Satisfaction, Elias Ciudad, Lori Boies

Posters - 2024

The American Medical Association Alliance (AMAA) conducted the Physician Family Experience Survey in early 2023.There has been an increase in physician burnout and suicide; suicide for physicians being at a higher rate than that of the general public. This is shown with 1 out of 10 physicians attempting considering suicide in 2021(7).

Literature has indicated that physician burnout leads to secondary burnout in the physician family (4).This survey sought to understand the current state of the physician family experience and compare this with historical studies through statistical analysis. This statistical study aims to identify and model predictors of life satisfaction …


Understanding The Evolutionary Conservation Of Ilp3 Gene Across Drosophila, Elias Ciudad, Cassandra Morales, Kendra Lancaster, Lori Boies Apr 2024

Understanding The Evolutionary Conservation Of Ilp3 Gene Across Drosophila, Elias Ciudad, Cassandra Morales, Kendra Lancaster, Lori Boies

Posters - 2024

Drosophila melanogaster is a commonly used model organism in genetics and developmental biology. Research on the insulin signaling pathway in D. melanogaster provides evidence that it is similar to the human pathway and involved in metabolism, growth and lifespan regulation (5). The Genomic Education Partnership’s (GEP) Pathways Project is a network analysis that focuses on insulin signaling in the genus Drosophila through the annotation of genes (1). The approach of the project is to understand the evolutionary change in genes across species over time in biological pathways and look at the growth and metabolic homeostasis (2). Insulin, in Drosophila, is …


Synthesis And Characterization Of Ugi Adducts Of Isatin, Cynthia Domergue, Kimberly Hernandez Apr 2024

Synthesis And Characterization Of Ugi Adducts Of Isatin, Cynthia Domergue, Kimberly Hernandez

Posters - 2024

B-lactam fragments have gathered attention in the chemistry field in being a pharmacophore for medicinal chemistry

- The Ugi reaction involves the reaction of an aldehyde, a primary amine, a carboxylic acid, and an isocyanide to generate α-acetoamido carboxamide derivates (Ugi adducts) -

We focused on the synthesis of the β-lactam derivatives: 1-Benzyl-N-(tert-butyl)-2-oxo-3(2-oxoazetidin-1- yl)indoline-3-carboxamide (4a), N-(tert-Butyl)-2-oxo-3-(2- oxoazetidine-1-yl) indoline-3-carbpxamide (4d) , and N- (tert-Butyl)-1-methyl-2-oxo-3-(2-oxoazetidine-1- yl)indoline-3-carboxamide (4e)

- The Ugi adducts of isatin were synthesized in TFE solvent by stirring the reactant mixture at room temperature and the conversion was monitored by TLC. The solvent was evaporated, and the crude product purified …