Medicine and Health Sciences Commons^™

Mechanism Of Action By Which 5-Nidr Acts As A Therapeutic Agent Against Brain Cancer, Seol Kim, Jung-Suk Choi

Undergraduate Research Posters 2015

Approximately 10,000 people in the United States are diagnosed annually with a brain tumor. In addition, the prognosis for brain cancer patients is poor as these cancers have low survival rates of less than 10%. One important chemotherapeutic agent used to treat brain cancer is temozolomide, an alkylating agent that causes cell death by damaging DNA. In this project, we tested the ability of a specific non-natural nucleoside developed in our lab, designated 5-NIdR, to increase the efficacy of temozolomide against brain cancer. Animal studies using xenograft mice were performed to evaluate the in vivo efficacy of this drug combination …

Safe Movement Practices By Stnas For Residents In Nursing Homes, Christine Fortuna

Undergraduate Research Posters 2015

Previous research reports that with compliance, safe movement programs and policies play a large roll in reducing worker injury and safe patient handling. The purpose for our research is to better understand the daily safe movement practices of State Tested Nursing Assistants as it relates to the safe handling and transferring of patients. We used Qualtric software to electronically survey 14 STNAs from Jenning’s Center for Older Adults Upper Level Neighborhood. The survey consisted of 7 forced choice questions and 19 open ended or follow up questions. The scope of our research covers the complexities of the daily tasks of …

Balance Training Application Of A Systematic Framework For Clinical Decision Making In Therapeutic Gaming For Older Adults, Brian Boccieri

Undergraduate Research Posters 2015

Falling is a major health concern for older adults. Balance is crucial in order to prevent falls. For balance to be functional an individual must be able to maintain balance while focusing on other tasks. For example, an individual must focus on more than just staying upright during walking while drinking a mug of coffee, or during standing while washing dishes. There are a countless number of daily activities that challenge balance. One of the problems with current clinical balance rehabilitation is that the training is often completed using isolated exercises that do not include the various other cognitive and …

Statistical Analysis Of Dasi Questionnaire And Modeling The Prediction Of Heart Failure Risk In Patients, Christian Negron

Undergraduate Research Posters 2015

9,880 patients were asked to complete the DASI questionnaire along with other questions to assess the predictability of heart failure risk. In this paper we attempt to reduce the amount of questions asked by hierarchical clustering of the question responses to determine if there is a change in the predictability of heart failure risk in patients. The data was modeled using Cox hazards multiple regression and validated through ROC and AUC. Our validation models show there is no difference between the usage of 12 and 6 DASI questions, therefore improving the simplicity of the questionnaire. Abbreviations: DASI, Duke Activity Status …

Ciliary Mechanosensation In Mdck Cells, Muhammad Tayeh

Undergraduate Research Posters 2015

Cilia are microscopic structures that extend from the surface of mammalian cells. Cilia can be categorized into two groups, primary cilia (non-motile) and motile cilia. Cilia are composed of tubulin subunits (microtubules) and covered by a plasma membrane. The physiological role of motile cilia has been very well documented, but the function of primary cilia remains largely unknown. It has been shown that primary cilia allow cells to sense and respond to mechanical stimuli. The ability for a cell to respond to mechanical stimuli is crucial for maintaining processes such as homeostasis. It has also been shown that defects in …

Developing Affordable Wet-Sample Electron Microscopy Integrated With A Temperature Controlled Sample Holder, Dan Terrano

Undergraduate Research Posters 2015

Scanning electron microscopy (SEM) is widely used to analyze the size, shape and composition of material systems. However, using this tool for analyzing systems such as particles suspended in solution, requires drastic sample alterations, such as precipitation and fixation. Besides altering their environment, this exposes the particles to the harsh conditions within an electron microscope, such as high vacuum and electron beam exposure. To this end, the first goal of this study was to develop methodologies for imaging wet samples using electron microscopy. This is realized by creating a sandwich structure containing the solution of interest between a partially electron …

The Effect Of Depression Symptoms On The Cardiac Autonomic Response To Positive Mood Induction, Elizabeth Golias, Khadeja Najjar, Brock Bodenbender

Undergraduate Research Posters 2015

Depression is characterized by a reduced capacity to experience pleasure (hedonic capacity). A growing literature suggests that hedonic capacity is supported by the sympathetic (SNS) and parasympathetic (PNS) branches of the autonomic nervous system. Both branches may work in a reciprocal fashion, or in tandem, reflecting co-activation of the SNS and PNS. While reduced PNS and increased SNS activity are associated with happy states among healthy individuals, preliminary findings suggest that depressed persons evidence blunted physiologic responses across a variety of emotion inducing stimuli. Much of this work, however, has examined PNS and SNS activity separately, and never with respect …

Cultural Differences In Coping And Depression Between Individuals Of Middle-Eastern And Non-Arab Backgrounds, Khadeja Najjar

Undergraduate Research Posters 2015

The Middle Eastern (Arab) demographic is a growing, yet neglected cultural group in mental health research. While Arabs are more predisposed to depression than other ethnic groups in US, little is known about mechanisms that account for this risk. One set of mechanisms may be the use of ineffective (maladaptive) coping or insufficient use of effective (adaptive) coping responses, which are robust predictors of depression in US samples, but virtually unexamined in Arabs. Further, the effect of a coping is influenced by culture, which, for Arabs, may change as a function of acculturation. Thus, the present study aimed to examine …

Effect Of Accelerometer Based Feedback On Paretic Upper Extremity Amount Of Use And Quality Of Movement: A Case Study, Mishgan Abdullah, Nathan Pohl, Amber Kuehn

Undergraduate Research Posters 2015

Purpose/Hypothesis: To determine the effects of accelerometer based feedback on clinical measures of paretic upper extremity (UE) recovery in people post-stroke and examine the relationship between these changes and paretic UE amount of use (AOU) measured by an accelerometer. Subjects: 7 people chronic post-stroke (5 males, 2 females; aged 62.03 ± 11.33 years) with an Upper Extremity Fugl-Meyer score range of 10-63 were included for this poster. Materials/Methods: Subjects wore wrist accelerometers for 3 weeks in the home. Clinical measures (Motor Activity Log, Stroke Impact Scale, Chedoke Arm and Hand Activity Inventory, and the ABILHAND) were assessed weekly. Data analysis …

Designing Tuftsin Conjugate For Directing Antimicrobial Ionophores To Macrophages, Sokhna Seck, Zeenat Razvi

Undergraduate Research Posters 2015

For all microorganisms, acquisition of metal ions is essential for survival in the environment or their infected host. Metal ions are required in many biological processes as cofactors for proteins or structural elements for enzymes. These ions play a role in chemotaxis, phosphorylation, transport of sugars and proteins, and initiation of DNA replication, among other things. It is critical for bacteria to ensure that metal uptake and availability meet its physiological needs; too little can impede these important biological processes, while too much can be toxic leading to radical formation which can cause damage to proteins and cell structures (Porcheron, …

Feasibility And Effects Of Accelerometer Based Feedback On Paretic Upper Extremity Amount Of Use In The Home Setting In Subjects Chronic Post-Stroke, Nathan Pohl, Amber Kuehn, Mishgan Abdullah

Undergraduate Research Posters 2015

Purpose : to (1) evaluate the feasibility of using accelerometers in the home to quantify how much subjects chronic post-stroke (PS) use their upper extremities (UE), (2) measure differences between amount of UE movement in subjects PS and a healthy control group (HC), (3) determine the effects of accelerometer based feedback on paretic UE use in subjects PS, and (4) determine if those effects are retained over time. Methods : Six subjects PS wore accelerometers for 3 weeks with two feedback sessions given during week two. Seven HC subjects wore accelerometers for one week. Accelerometer based outcome measures included relative …

Action For Dental Health Year Two Progress Report, American Dental Association

Action for Dental Health

No abstract provided.

Er Referral Models Summary, American Dental Association

Action for Dental Health

No abstract provided.

Infographic: Why Oral Health In Older Adults Is Important, American Dental Association

Action for Dental Health

No abstract provided.

Cell Surface Sialylation Status Of Monocytes And Macrophages, Henry Wang, Dan Wang

Undergraduate Research Posters 2015

Sialic acids (SAs), a family of 9-carbon containing acidic monosaccharides, often terminate the glycan structures of cell surface glycoconjugates such as glycoproteins and glycolipids. The levels and linkages of sialic acids named as sialylation status vary as cell environment changes related to both physiological and pathological processes. Changes in sialylation of cell surface modulate cellular activity. SAs are highly involved in the immune system, however, the sialylation status related to individual immune cells and their activation state and functions are still unknown. In this study, we used a newly developed LC-MS/MS method to examine the cellular SA content during THP-1 …

Visual Voices Approved Consent Form, Collyn Baeder, Zoe Hull, Rebecca Masterjohn, Virginia Sedarski, Adrian Jung, Michaela A. Hoffman, Nicole O'Brien

Visual Voices: An Arts-Based Assessment of the Perceived Identity of Aging Maine Residents

Approved project consent form for UNE student project Visual Voices: An Arts-Based Assessment Of The Perceived Identity Of Aging Maine Residents, designed to investigate the topics of perception, identity, and aging.

Between February and May 2015, over the course of twelve sessions, the UNE team met with six female residents of the Park Danforth senior living community in Portland to have conversations and create art about how the residents perceive themselves in contrast to how they feel perceived by important people in their lives, such as friends, family, and healthcare providers.

This form documents the scope of the project …

Visual Voices Weekly Session Scripts, Collyn Baeder, Zoe Hull, Rebecca Masterjohn, Virginia Sedarski, Adrian Jung, Michaela A. Hoffman, Nicole O'Brien

Visual Voices: An Arts-Based Assessment of the Perceived Identity of Aging Maine Residents

Eleven weekly session scripts for UNE student project Visual Voices: An Arts-Based Assessment Of The Perceived Identity Of Aging Maine Residents. This project was designed to investigate the topics of perception, identity, and aging. Between February and May 2015, over the course of twelve sessions, the UNE team met with six female residents of the Park Danforth senior living community in Portland to have conversations and create art about how the residents perceive themselves in contrast to how they feel perceived by important people in their lives, such as friends, family, and healthcare providers.

Validation Of The Health Efficacy And Assertiveness Scale, Lee Stadtlander, Amy Sickel, Martha Giles

2010-2016 Archived Posters

Recently, health care has required the role of “patient" to change from a receptive role to an active one. Patients' responsibilities for discussing health with their physicians require greater health assertiveness and efficacy. There is not a validated survey examining patient assertiveness and self-efficacy. This study addresses this issue.

Health Behaviors, Hardiness, And Burnout In Mental Health Workers, Jeremiah Brian Schimp

2010-2016 Archived Posters

This study addressed the connection between health behaviors, hardiness, and burnout in 223 mental health workers who completed online surveys of burnout, demographics, hardiness, and health behaviors. The results suggest mental health workers are better able to maintain their emotional energy through the cultivation of hardiness and management of stress.

Ceo Duality And Performance Of Not-For-Profit Hospitals, Anh Ngoc Pham

2010-2016 Archived Posters

Depending on their needs for enhancing and sustaining their business and market values, some firms choose to operate with a corporate governance structure of CEO duality, in which an executive serves as the CEO and the chairperson of the board of directors. This study used multiple regression data analyses of financial indicators from 146 U.S. not-for-profit hospitals selected from the Office of Statewide Health Planning and Development database of California, for the period from 2009 to 2012. The results of this study suggested CEO duality and presence of physicians on healthcare governance were not related to financial performance of not-for-profit …

Predictors Of Non-­Adherence To Medical Follow-­Up Care Among African Americans With Hiv/Aids, Phyllis D. Morgan, Cynthia B. Banks, Joshua Fogel

2010-2016 Archived Posters

Persons living with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) who do not adhere to their medical follow-­ up appointments tend to have poorer health outcomes compared to HIV/AIDS patients who adhere to their medical follow-­up appointments (Lima et al., 2009). This study examined factors that influence non-­adherence of African-­Americans with HIV/AIDS to medical follow-­up appointments.

The Impact Of Centeringpregnancy Implementation, Carole Ann Moleti

2010-2016 Archived Posters

Evaluation of 6 Centering Pregnancy Group Prenatal Care cycles showed the logic models supported implementation and expansion of Centering Groups at 2 federally qualified health centers. There was adequate progress toward site approval with favorable method fidelity scores in addition to patient and staff satisfaction ratings using the Centering Counts data collection system. Outcomes in 33 participants demonstrated beneficial effects on key indicators.

Technology As A Health Intervention And The Self-Efficacy Of Men, Karen Denise Maxwell

2010-2016 Archived Posters

Mortality rates are higher for men than women. Limited knowledge exists regarding the specific components needed to design technology health tools to appeal to men. This study examined the relationship between the use of technology health tools and the role of self efficacy in men and participation in healthy lifestyle behaviors.

The Burden Of Avian Influenza Viruses In Community Ponds In California, Zin Htway

2010-2016 Archived Posters

This research was a baseline study of the proportion of influenza A virus (IAV) in urban and rural communities in California. The population was artificial recirculating water ponds in the geographic locations of rural and urban Californian communities. Surface water samples were collected from artificial recirculating ponds in California.

Development And Validation Of The Body Knowledge Questionnaire, David A. Hernandez, Cheri Ann Hernandez

2010-2016 Archived Posters

This study evaluated the psychometric properties (validity and reliability) of a new instrument,the Body Knowledge Questionnaire(BKQ), which measures weight management integration—an individual’s attitudes, preferences, and behaviors associated with weight management. The BKQ has potential for use in weight management practice areas to ameliorate the global obesity problem.

Donut Hole Spring 2015, Medicare Donations & Design Committee

Donut Hole Newsletter

No abstract provided.

Donut Hole Summer 2015, Medicare Donations & Design Committee

Donut Hole Newsletter

No abstract provided.

Literature Review Of Nosocomial Infections Passed Through Nurses' Personal Items, Corina Hickman

Student Research Posters

As defined by the encyclopedia, nosocomial infections are infections whose development is favored by a hospital environment, such as one acquired by a patient during a hospital visit or one developing among hospital staff. There has been more of a prevalence of hospital-acquired infections that are linked directly to medical personnel – especially nurses. Nurses have the most contact with patients and are potentially putting patients at highest risk for nosocomial infections. Even though nurses are following isolation precautions and standard hand washing in between patients; there are still a few things on nurses that could be harmful to their …

Stormwater Management And Residents Perceptions, Mark Gatesman

Undergraduate Research Posters 2015

Stormwater runoff is a major problem in many residential municipalities. Rain water washes pollutants and chemicals off of streets, driveways and lawns. Stormwater management practices help filter out harmful particles before they enter into our water ways. The goal of this project was to assess green infrastructure stormwater practices throughout Cuyahoga County. We assessed 165 sites in over 10 cities in Cuyahoga County. We examined bioswales, bioretention basins, and rain gardens. Sites were visited in late May through early June and revisited in mid-July to early August. We compared spring condition of plants and gardens and recorded resident’s perceptions whether …

Acoustic Objective And Subjective Measurements Of Noise Levels In Various Places Of Worship And The Potential Consequences On The Auditory System, Celeste Thomas

Undergraduate Research Posters 2015

The purpose of this study is to record the objective and subjective measurements of noise levels in ten religious institutions of various faiths: Apostolic/Pentecostal, Baptist, Catholic, Muslim, Non-Denominational, and Seven-Day Adventist places of worship within the greater Cleveland area; in conjunction with the assessing the hearing sensitivity of the ministerial staff members who are most susceptible to prolonged noise exposure. The objective is to generate a statistical analysis of the objective acoustical measurements of primary church services of all participating religious institutions determine if the noise levels are loud enough to cause potential harm to the auditory system. The researcher …