Medicine and Health Sciences Commons^™

Effect Of P38 Kinase And Cell Cycle Position On The Expression Of The Pro-Apoptotic Bcl2 Family Member Puma In Skeletal Myoblasts, Victoria Bensimon, Briana Boslett

Undergraduate Research Posters 2016

Skeletal muscle regeneration relies on myoblast stem cell differentiation and is a crucial response to muscle injury caused by trauma and numerous diseases. In skeletal myoblasts, cell death and differentiation are mutually exclusive biological endpoints that are both induced by culture in differentiation media. MyoD, the master muscle- specific transcription factor, is well-known to regulate the expression of muscle specific genes such as myogenin and the ensuing differentiation. However, we have previously reported that MyoD also plays a critical role in the expression of PUMA and apoptosis, rather than myogenin and differentiation, in a subset of myoblasts, thus diminishing the …

Reducing Violence On The Psychiatric Unit, Salome Accardi, Carlyn Chamberlain, Mafe Chase, Melinda Green

All Nursing Boot Camp Posters

No abstract provided.

Pictorial Information Leaflets (Pils) In Conjunction With Verbal & Written Home Care Medication Instruction, Shawna Blix, Jennifer Hof, Cheri Lebrun

All Nursing Boot Camp Posters

No abstract provided.

Initiating Early Post-Cesarean Feedings Is Best Practice!, Lisa Fellin, Sherry Hutton, Cindy Kenyon

All Nursing Boot Camp Posters

No abstract provided.

Evaluating Human Cell Survival And Dna Damage After Exposure To Various Amounts Of Chlorine Dioxide And Exploring Its Use As A Potential Cancer Chemotherapy Agent, Niuska Mariana Alvarez Fuenmayor

SURF - Summer Undergraduate Research Fellowship Projects

Chlorine Dioxide (ClO₂) is a synthetic, green-yellowish gas with a chlorine-like, irritating odor that is used for the treatment of drinking water and food preservation. The aim of this study was to evaluate the genotoxic potential of the chlorine dioxide in mammalian cells and to determine what dose of ClO₂ is tolerable by normal cells and cells with aberrant DNA repair genes. Human and mouse embryonic cells were treated with various ClO₂ dilutions ranging from 2.5 mM to 25 mM. The cell viability and metabolic activity was determined via MTT, a colorimetric assay. Human HEK293 cells …

Medical Education Digest, Vol. 18 No. 1 (January-February 2016), Nova Southeastern University

Medical Education Digest

No abstract provided.

Baystate Medical Practices Annual Report - 2016, Andrew Artenstein Md

Baystate Medical Practices Annual Report

No abstract provided.

Point-Of-Care Testing In Primary Care May Reduce Overall Cost And Improve Both Patient Satisfaction And Efficiency, Eric A. Sadler

Physician Assistant Scholarly Project Posters

• Objective: Increased demands for primary care are forcing clinical offices to deliver cost and time efficient care while providing exceptional patient experiences. Traditional lab testing methods require multiple steps for the patient and provider. Test results are not available until a later time which may delay decision making, patient discussion and medical planning. Point-of-care testing (POCT) provides an alternative that allows the patient to have testing, discuss the results and establish a treatment plan during a single office appointment.

• Design: A review of literature examined studies that compare cost-effectiveness, patient satisfaction and efficiency of POCT with traditional laboratory …

University Of South Alabama College Of Medicine Annual Report For 2016-2017, College Of Medicine

COM Annual Reports

This Annual Report of the College of Medicine catalogues accomplishments of our faculty, students, residents, fellows and staff in teaching, research, scholarly and community service during the 2016-2017 academic year.

Libro De Actividades Por El Mes Nacional De La Salud Dental Infantil [Spanish Language Version: National Children's Dental Health Month Activity Book] (2016), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

Non-Hdl-C Or Apolipoprotein-B Versus Ldl-C Screening For Evaluation And Treatment Of Atherosclerotic Cardiovascular Disease, Grant Coauette

Physician Assistant Scholarly Project Posters

• Lowering low-density lipoprotein cholesterol (LDL-C) concentration in the population has been a goal of researchers and clinicians to prevent atherosclerotic cardiovascular disease (ASCVD).

• Controversy surrounds using [LDL-C] as the primary lipid biomarker to evaluate the risk of cardiovascular events. An article search dating back to 2005 of PubMed and The Cochran Library was conducted.

• The purpose of this investigation was to determine if LDL-C should be the primary lipid biomarker used to determine ASCVD treatment and prevention. This investigation researched other lipid biomarkers and targets to determine clinical relevance and if the level of those markers more …

Screening For Cardiovascular Disease In Children, Jesse Fladmark

Physician Assistant Scholarly Project Posters

Introduction: Cardiovascular disease is one of the leading causes of death in the world with significant burden on the health care system.

Review of Literature: The focus of this paper is to look at previous studies, mostly systematic reviews and metaanalysis, in search of various clinical screening methods in the pediatric population for determining cardiovascular disease risk. Waist to height ratio can be used to screen children for cardiovascular disease with a specificity of 96% when using 0.55 as the cut-off point. An increase in waist circumference along with increased BMI places a child at a much higher risk of …

Does Normalizing Gut Microbiota Decrease Exacerbation In Ibd, Franchesca Cook

Physician Assistant Scholarly Project Posters

Inflammatory bowel disease (IBD) including Crohn’s Disease (CD) and Ulcerative Colitis (UC) has become a more common diagnosis. The number of screenings for IBD has increased, drawing more attention to finding the cause. Researchers are finding that a change in diet, increased stress levels, and overuse of antibiotics may contribute to IBD by changing the gut microbiota (Skrautvol et al., 2011; Bernstein, 2010). Prebiotics and probiotics, an individualized anti-inflammatory diet, and lifestyle modification to decrease stress are all currently undergoing evaluation to discover a possible role in the reversal of IBD insult to the normal flora of the gut. This …

Nrf2 Pathway And The Reduction Of Oxidative Stress, Stephanie Jacobs Uselman

Physician Assistant Scholarly Project Posters

Oxidative stress has been linked to cellular damage initiating disease processes such as cardiovascular disease, diabetes, and cancer. The Nuclear factor erythroid-derived 2(Nrf2) pathway (Figure 1) aids in age-related cellular decline. The purpose of this study was to define the relationship between Protandim, its activation of the Nrf2 pathway, and decline in oxidative stress and cellular damage. The literature review included journal articles obtained from PubMed, Google scholar, and Cochrane review within the past 5-10 years, and contained both animal and human studies. The methods used in the animal studies included ANOVA, the standardized t-test, and the Neuman-Keuls post-test. P<0.05 was considered statistically significant. The human study included healthy participants, both male and female, age 29-78 with or without a specific medical diagnosis. Statistical analysis was based on the standardized t-test with a value of p<0.05 considered statistically significant. Liu et al. (2009) conducted a study investigating Protandim’s ability to suppress cancer tumor formation. Tumor incidence declined by 33% and multiplicity of skin tumors by 57% with p = 0.003. Superoxide dismutase increased 35%, catalase 58%, and manganese superoxide dismutase 21%. In 2013, Reuland et al. conducted a study to determine if Protandim could activate the Nrf2 pathway and induce antioxidant enzymes, thereby protecting cardiomyocytes from apoptosis. Results indicated that treated cardiomyocytes showed increased levels of Nrf2 nuclear accumulation, activation of endogenous antioxidant enzymes, and protection against cell targeted oxidative stress (p<0.05). Quereshi et al. (2010) completed a study to delineate if Protandim decreased oxidative stress through the Nrf2 pathway. After six months of supplementation, TBARS decreased by 48% (p=.006), and plasma osteopontin decreased by 57% (p=.018). In 2005, Nelson et al. conducted a study to determine if Protandim decreased cellular damage. After 30 days of supplementation, TBARS declined by 40% (p =0.0001), at 120 days, TBARS declined by 40-54% (p =0.002), and superoxide dismutase and catalase increased by 30% and 54% respectively. The results from studies indicate that Protandim’s activation of the Nrf2 pathway increased endogenous antioxidant availability, resulting in decreased oxidative stress and age related cellular damage.

Predictors Of Prolonged Recovery From Concussion, Patrick W. Riley

Physician Assistant Scholarly Project Posters

• Sport-related concussion has been thrust to the forefront of medicine in recent years.

• A high degree of variability in clinical presentation and length of recovery has made management of this condition difficult.

• This review examines whether pre-existing risk factors or sign and symptom based variables exist to reliably predict a patient’s likelihood to experience a protracted recovery from concussion.

• The review of literature revealed heterogeneous results.

• This is due, in part, to the variability in the definition of prolonged recovery, ranging from seven to 90 days. Despite this variability, several factors emerged as having useful …

Helmet Therapy Vs. Conservative Therapy For The Treatment Of Positional Skull Deformations, Whitney Thompson

Physician Assistant Scholarly Project Posters

• Plagiocephaly and brachycephaly are skull deformations that occur in nearly half of all infants. These deformities are present at birth or can develop shortly after birth due to head positioning while lying supine. Depending on the severity of the deformity, infants may develop negative long-term developmental outcomes. There are generally two ways to treat such patients; repositioning or with use of orthotics (helmet therapy).

• A study of systematic reviews and cohort studies was completed to determine if orthotics (helmet) therapy is significantly more effective than repositioning therapy.

• The study indicated that infants diagnosed with moderate to severe …

A Multimodal Approach To Preventing And Treating Alzheimer’S Disease, Jason B. Smith

Physician Assistant Scholarly Project Posters

As of 2015 over 47 million people worldwide are diagnosed with Alzheimer’s disease (AD). The incidence of AD increases with age, and affects males and females equally. Current pharmacologic treatment includes two classes of drugs. The purpose of this study was to determine if a multimodal approach (i.e. diet, exercise, cognitive stimulation) towards the prevention and treatment of AD would be more beneficial than pharmacologic therapy alone. Research methods included reviewing peer reviewed journal articles published within the past five years obtained from PubMed, Dynamed, Cochrane, CINAHL, and Clinical Key. Ehret and Chamberlin (2015) found donepezil (Aricept) increased MMSE scores …

A Review Of Barrett's Esophagus, Suzanne M. Zayan

Physician Assistant Scholarly Project Posters

Barrett’s Esophagus is a premalignant condition that predisposes patients to the development of esophageal adenocarcinoma.

•Esophageal adenocarcinoma dramatically rising over several decades; survival rates of less than 17% in a five year period.

•Management and treatment continues to evolve: use of radio-frequency ablation effective to treat low grade dysplasia

•Studies of risk factors and treatment options explored:

Efficacy and durability of endoscopic radiofrequency ablation for treatment of low grade dysplasia as option for metaplasia eradication

–Gastrointestinal pathologist expert reviews ensure identification of dysplasia prior to treatment
–Appropriate endoscopic surveillance intervals
–Gastroenterology guidelines for screening and surveillance for long term management …

Factors Influencing Esi Accuracy, Dawn Gonzales, Angela Hahn, Anna Vernon

All Nursing Boot Camp Posters

No abstract provided.

Bilal, Bilal, Tsos

TSOS Interview Gallery

Bilal was 23 years old when he drowned in Greece. He was cheerful, intelligent, and full of energy.

He was a journalist in Afghanistan who received a death threat from the Taliban. His family decided that he should flee the country alone for survival since they couldn’t afford for the whole family to go.

He escaped from the camp in Moria by finding a hole in the fence. He outran the police, found a ship in port, and jumped on it as it was leaving. He later had 10 unsuccessful attempts to leave Greece for Germany. He was caught by …

Zurvan, Zurvan, Tsos

TSOS Interview Gallery

Zurvan and his family had a good life in Afghanistan. He worked as a clerk in a spice shop. After doing business with a foreign company, the Taliban threatened him with death. To escape this threat, he and his family escaped to Iran and hired a smuggler to get them to Turkey. From there, they traveled to Greece in an overloaded boat. They have been living in a camp in Greece, stuck in limbo, ever since. Zurvan feels hopeless, like everyone in the camp is being treated in an inhumane manner. He also feels guilty for bringing his children into …

Aarash, Aarash, Tsos

TSOS Interview Gallery

As an anti-corruption journalist in Afghanistan, Aarash’s family’s life was threatened by warlords. His car was shot at, their guesthouse was bombed, and later when they were threatened at gunpoint, they tried to make a new life in India. But in India, they discovered difficulties in obtaining permanent visas so they had return to Kabul where they hid at a friend’s house for 20 days while obtaining documentation to flee to Turkey. Once in Turkey, they learned that Afghan registries had been closed since 2010. They determined that they needed to either apply for asylum in Turkey or leave for …

Idiris, Idiris, Tsos

TSOS Interview Gallery

Idiris is an 18-year-old Somalian refugee now living inUtah. He describes his life, mentioning that he only lived in Somalia for six years then moved to Ethiopia, where he stayed for seven and a half years.His life inEthiopia was peaceful and happy in comparison to Somalia, where Idiris and his family witnessed continuous violence. Idiris’s father eventually learned of the opportunities and education available in America and decided to move his family there for a better life, leaving behind family and friends. Coming to America, Idiris and his family did not know what their new home would be like. They …

Improving Handovers Between Emergency Department And In Patient Cardiac Units, Amy Engstrom

All Nursing Boot Camp Posters

No abstract provided.

College Of Nursing, Dave Graves, Karissa Kuhle, Emily Weber

College of Nursing Magazine

Features
[Page] 2 — Path to awarding graduate degrees has been worth the effort.
[Page] 6 — Work/work balance—Faculty members discuss teaching and health-care careers.
[Page] 10 — Finding her niche: A class section spurs Kim Nearhood to find her passion.
[Page] 12 — West River Nursing Program graduates first DNP class.
[Page] 13 — Certified nurse midwife Brenna Tate gets to experience miracles.
[Page]14 — Lesley Cook and Julie Jones found ideal careers with VA.
[Page] 16 — It took some time but Susan Leddy found a role she loves.
[Page] 17 — Grant Jaspers makes the most of …

College Of Pharmacy And Allied Health Professions, South Dakota State University

Jackrabbits Script and Scope (Formerly called College of Pharmacy and Allied Health Professions Magazine)

[Page] 2 Avera’s impact The Avera Health and Science Center, the college’s home, has been open for five years. The facility is a hub of education and professional development for students.
[Page] 4 Transformational gift Wenfeng An is officially introduced as the Markl Faculty Scholar in Cancer Research.
[Page] 6 Pediatric drug development Fall convocation keynote speaker addresses struggles with developing drugs for youth.
[Page] 8 MLS students earn white coats Class of 2016 MLS students receives white coats.
[Page] 10 SDSU Health College of Pharmacy joins other colleges to address the wellness of the campus community.
[Page] 12 Take …

Serum Biomarkers Compared To Neural Imaging In The Differentiation Of Stroke Etiologies, Kevin Conboy

Physician Assistant Scholarly Project Posters

• Stroke is a leading cause of disability and morbidity and the fourth leading cause of death in the United States, and the second leading cause of death worldwide.

• Early restoration of blood flow is the most effective treatment of ischemic stroke by intravenous thrombolytic therapy within 3-4.5hrs of symptom onset.

• Patient outcomes have been shown to improve with earlier thrombolytics, each 15 minute increment increases survival by 3.0-4.0%.

• Non-contrast CT is the current standard for differentiation of stroke. It is beneficial due to speed of acquisition and its high sensitivity in ruling out hemorrhagic stroke.

• …

Sublingual Immunotherapy: Is It A Viable Option To Subcutaneous Immunotherapy When Treating Allergic Rhinitis?, David Ryan Kesterson

Physician Assistant Scholarly Project Posters

• Background: Allergic rhinitis (AR) is a very common debilitating disease that can be detrimental to one’s lifestyle, work, and home life. Immunotherapy is the only treatment option that has disease modifying capabilities with a proper therapeutic regimen. Subcutaneous immunotherapy (SCIT) was developed over 100 years ago and has been the gold standard in immunotherapy for many years in the United States. During these years many adverse reactions have been reported with SCIT along with non-adherence to total treatment. The introduction of sublingual immunotherapy (SLIT) over 20 years ago gave providers a promising alternative to SCIT.

• Method: A review …

Chemotherapy Cancer Treatment And Cognitive Dysfunction, Caitlyn Cameron

Physician Assistant Scholarly Project Posters

The prominence of cognitive dysfunction because of cancer treatment, referred to as “chemo brain” is increasing due to the number of cancer survivors. Research on chemotherapy related cognitive dysfunction has been focused on breast cancer survivors. The purpose of this study was to establish if a connection between chemotherapy cancer treatment and cognitive dysfunction exists. This evaluation of literature explored PubMed, DynaMed, Psychiatry Online, and Cochrane which compared cognitive abilities before and after chemotherapy cancer treatment. This paper examined the research over the last 10 years, of women ages 18-70 and the connection between chemotherapy treatment and cognitive dysfunction. Jansen …

Vitamin D Supplementation And Systemic Lupus Erythematosus, Pamela Rangen

Physician Assistant Scholarly Project Posters

• Patients with systemic lupus erythematosus (SLE) are prone to hypovitaminosis D because of their photosensitivity.

• Vitamin D has beneficial effects not only on bone metabolism but also on the function of the immune system.

• Vitamin D levels depend on many variables, including sun exposure, age, ethnicity, body mass index, use of medications and supplements.

• Patients with SLE avoid the sun because of photosensitive rashes and potential for disease flare, so adequate oral supplementation is critical.

• In addition, to the traditional known metabolic activities, vitamin D has been shown to modulate the immune system, and its …