Medicine and Health Sciences Commons^™

Parenteral Ascorbic Acid For Treatment Of Sepsis, Lindsey Hiatt

Physician Assistant Scholarly Project Posters

Sepsis kills nearly 1 million people each year in the United States and sepsis-related hospitalizations cost approximately $24 billion annually (Paoli, Reynolds, Sinha, Gitlin, & Crouser, 2018). Current treatment guidelines are limited to targeted antibiotics and hemodynamic support. While antibiotics are the definitive treatment to eradicate the infectious pathogen, there are currently no standard-of-care treatments that consistently and successfully attenuate the damage sustained to the body by its own inflammatory response to infection. Many different treatments have been trialed and failed to show improved outcomes. Vitamin C, or ascorbic acid, has long been associated with supporting immune function, and has …

The Use Of Dhea In The Treatment Of Depression, Bryan Tipton

Physician Assistant Scholarly Project Posters

No abstract provided.

Outcomes In Treatment Of Major Depressive Disorder: Pharmacogenomic Testing Vs. Treatment As Usual, Zachary Horoshak

Physician Assistant Scholarly Project Posters

• The goal of this scholarly project was to evaluate the efficacy of pharmacogenomic testing (PGx) versus treatment as usual (TAU) in the treatment of major depressive disorder (MDD). According to Huang & Lin (2015), MDD is characterized by multiple signs and symptoms consisting of mood, vegetative, cognitive, and even psychotic behaviors that may cause substantial impairment in the functioning and quality of life in an affected individual. This literature review consisted of articles found in PubMed, Cochrane, and PsychINFO which were extensively reviewed. Articles prior to 2008 were excluded due to the ever-changing landscape of PGx testing. In this …

Use Of Beta-Antagonists Or Hmg-Coa Reductase Inhibitors For Cardioprotection During Chemotherapy In Oncology Patients, Nicole Streich

Physician Assistant Scholarly Project Posters

Over the years, oncologists are better able to fight cancer and have increased cancer survival, but we are also finding that these lifesaving therapies can affect the heart and other parts of the body in a negative way. Chemotherapy is excellent at destroying cancer cells, but it also causes collateral damage to other healthy cells. There are certain chemotherapeutic agents that are known to cause cardiotoxicity. Currently we are monitoring the heart function of the patients who are receiving these cardiotoxic drugs prior to starting the chemotherapy as well as during and after treatment. However, there are currently no recommendations …

Glucagon-Like Peptide-1s Compared To Sulfonylureas In The Treatment Of Adults Diagnosed With Type Ii Diabetes Mellitus In Primary Care, Tracy Kirchner

Physician Assistant Scholarly Project Posters

Type II diabetes mellitus (T2DM) is a prevalent disease in our country. Bullard et al. (2018) report approximately 21 million adults have T2DM in the United States. “The total estimated cost of diagnosed diabetes in 2017 is $327 billion, including $237 billion in direct medical costs and $90 billion in reduced productivity” (Yang et al., 2018). Treatment of T2DM is individualized to each patient based on their co-morbidities, fiscal responsibility, and route of administration options. Sulfonylureas and Glucagon-like Peptide-1s (GLP-1) are two classes of antidiabetic drugs that are available for use as second line treatment options after metformin. This review …

Obesity: Modern Medicine Vs. Lifestyle, Jenny Christianson

Physician Assistant Scholarly Project Posters

• Obesity is a rising epidemic, and is one of the most common, costly and preventable health problems the world is experiencing today (Center for Disease Control and Prevention, [CDC], 2017).

• From this, it is important to establish an effective treatment plan that can be implemented across the nation for maximum patient benefit.

• Lifestyle changes such as diet and exercise are important to any health care plan and are equally necessary to reduce health risks. However, in certain patients, lifestyle changes are not enough due to the maladaptive biologic process in their brain. Thus, additional treatment options need …

Evolution Of Occupational Therapy Practice: Life History Of Kathlyn L. Reed, Ph.D., Otr, Faota, Mlis, Tristen Smith, Audrya Tarango

Oral History Posters

This life history is one of 30 life history interviews which are part of a larger project, Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) at the National Level and Beyond. The purpose of the study is to provide current and future generations of occupational therapists a view of the history and how occupational therapy practice has evolved from its inception to current practice through the life history stories of occupational therapists who have held leadership roles at the national level and beyond. It is anticipated that the life history process will be a powerful way …

Evolution Of Occupational Therapy Practice: Life History Of Julie D Bass, Phd, Otr/L, Faota, Michaela Zins, Taylor Beatty

Oral History Posters

Objective: The purpose of the life history of Julie Bass, PhD, OTR/L, FAOTA, is to gain an insight into her life, her leadership experiences, and her years of work in the occupational therapy (OT) profession to provide current and future generations of occupational therapists a view of how occupational therapy practice has evolved over time.

Method: An in-depth, semi-structured interview was guided by an interview schedule prepared by the project directors. The interview took place via Zoom conference at the University of North Dakota and lasted two hours. The interview was transcribed verbatim and coded with 22 codes. The codes …

Fertility Options For Women With Endometriosis: In Vitro Fertilization Versus Surgical Excision Or Ablation, Jenny L. Brown

Oral History Posters

Endometriosis negatively affects the fertility of many women of reproductive age worldwide. Some women with endometriosis are able to conceive without reproduction assistance, while others require medical intervention. In vitro fertilization and surgical management are available and widely used in the treatment of endometriosis associated infertility. In vitro fertilization has been found to be effective in women with stages I-IV endometriosis, with varying degrees of success at each stage. These varying results may be due to oocyte quality and availability as well as endometriosis location. Surgical excision and/or surgical ablation of endometriosis/endometriomas may also improve chance of successful pregnancy but …

Analysis Of Wind Instruments On Orofacial Anatomy: A Review Of Literature, Regina M. Dixon, Samantha Chavez

Dental Hygiene Student Scholarship

The focus of this review of literature is on orofacial anatomy and their association with the longevity of wind instrument use. The importance of how playing wind instruments creates a disadvantage for the oral cavity and therapeutic approaches to decrease the adverse effects. Using the university’s library database and PubMed, the authors performed a thorough search on the literature of our topic. Specific key terms such as wind instrumentalists, oral health, orofacial anatomy, and therapy were used to conduct our search. The searched was limited to the English language and within five years of publications. The findings acknowledged pathologically infectious …

The Effect Of Artificial Sweeteners In Chewing Gum, Helpful Or Harmful?, Taylor Rue, Emily Liebe

Dental Hygiene Student Scholarship

Objective/Aims: This review of literature was designed to analyze the effects of artificial sweeteners in chewing gum in the oral cavity. The intent was to recognize which formulations of artificial sweeteners in chewing gum lead to beneficial outcomes in the oral cavity and which formulations lead to harmful effects.

Methods: The review of literature analyzed the conclusions of primary and secondary resources accumulated from PubMed. Multiple scholarly studies were filtered based upon meta-analysis, cross-sectional, and cohort studies. The following key terms were used: artificial sweetener, chewing gum, plaque, saliva, microbes, and oral health. A summative report was created based upon …

Efficacy Of Statin Therapy In The Elderly, Alyssa M. B. White, Hillary R. Mishcon, John Redwanski, Ronald D. Hills Jr

Pharmacy Student Posters

Statins are one of the most heavily prescribed medications. The 2018 ACC/AHA guidelines support statin therapy for most older adults, but recommendations are less clear for those over 75. The literature was systematically reviewed for evidence of the efficacy of statin treatment in different patient populations. Significant evidence was found supporting a decreasing association between low-density lipoprotein cholesterol (LDL-C) and mortality as well as decreasing statin efficacy with increasing age. The consequences of unnecessary statin therapy can be severe for older adults. Improved methods for evaluating atherosclerotic cardiovascular disease (ASCVD) risk, such as using negative markers to help identify those …

Tolle Lege Works Published In 2019, Mcquade Library

Bibliographies

Compiled Tolle Lege bibliography of works published by members of the Merrimack College Community in 2019. Works include journal articles, books, book chapters, conference presentations and posters, and more.

Graduate Medical Education Annual Report 2018-2019, Children's Mercy Hospital

GME Annual Reports

Annual report of the Children's Mercy Hospital Graduate Medical Education department, including pediatric residency, internal medicine/pediatrics residency, fellowship programs, medical students, continuing medical education, and library services.

Developing And Validating Tools To Assess Higher Level Cognition In Children And Adolescents, Brainscan, Western University, Bobby Stojanoski, Marc Joanisse, Ryan Stevenson, Cambridge Brain Sciences Inc.

Project Summaries

Collaborating with CBS, we will create a unique platform for understanding, detecting and predicting delays in cognition during the formative period from childhood to adolescence. The aim of this project is to develop and validate a battery of tests specifically for children and adolescents between the ages of 7 and 15 to measure various aspects of higher-level cognitive abilities. These include short-term and episodic memory, planning, reasoning, verbal abilities and executive functioning (those processes necessary to control behaviour, such as controlling attention and inhibition, working memory, reasoning and problem solving).

Multi-Area Organization Of Saccade-Evoked Traveling Waves, Brainscan, Western University, Julio Martinez-Trujillo, Lyle Muller, Adam Williamson

Project Summaries

In this project, we will employ new, large-scale electrophysiological recording techniques to sample widely across the visual system. It will allow us to test our hypothesis that neural traveling waves coordinated across multiple areas contribute to perceptual stability during eye movements. Using our newly developed signal processing technique to track traveling waves moment-by-moment in noisy multichannel data, we will detect and quantify them across multiple visual areas.

Detecting Fine-Grained Population Codes In Human Prefrontal Cortex, Brainscan, Western University, Marieke Mur, Julio Martinez-Trujillo, Ravi Menon, Joe Gati

Project Summaries

In this project, we will develop techniques for improving our measurement resolution so that we can gain access to prefrontal population codes. We will combine high-field fMRI with pattern analysis techniques to unlock population coding in the prefrontal cortex. This is essential for understanding how the brain supports higher-order cognition, and ultimately, for treating dysfunctions of cognitive flexibility in the clinic.

Can Self-Efficacy Training Improve Memory And Functional Activation In Older Adults With Mild Cognitive Impairment? A Proof-Of-Concept Intervention Study, Brainscan, Western University, Lindsay Nagamatsu, Derek Mitchell, Paul Minda, Amer Burhan, Becky Horst

Project Summaries

The goal of this study is to examine the changes in brain activity after a memory self-efficacy training program to better understand the mechanisms of memory self-efficacy. We will conduct a proof-of-concept six-week memory self-efficacy intervention in older adults with MCI, in order to demonstrate that self-efficacy impacts brain function. This will allow us to determine whether self-efficacy interventions may be a potential strategy for combating AD in the future.

Developing A Mechanistic Understanding Of Crossmodal Reorganization Following Sensory Loss, Brainscan, Western University, Blake E. Butler, Brian Allman, Ravi Menon

Project Summaries

Our long-term goal is to understand how plasticity reshapes circuits in the brain in response to atypical early experiences. This will allow us to better understand how the Deaf brain processes the world around us, and will make clear the challenges that must be overcome to optimize the function of cochlear implants and prostheses designed to restore sensory functions more broadly.

The Risk Of New-Onset Epilepsy And Refractory Epilepsy In Older Adult Stroke Survivors, Jorge G. Burneo, Tresah C. Antaya, Britney N. Allen, Andrea Belisle, Salimah Z. Shariff, Gustavo Saposnik

Neuroepidemiology Research Unit Project Summaries

Research Summary: Key Findings

• Stroke is a common cause of epilepsy in older adults, but little is known about stroke-related epilepsy or its outcomes in this population.
• 1.1% of older adult stroke survivors developed epilepsy in this study, of whom 12.9% developed refractory epilepsy, indicating that this population is particularly responsive to treatment.
• Over 85% of deaths in this population are not due to stroke or epilepsy.

January 2019, New England Osteopathic Heritage Center

New England Osteopathic Heritage Center Newsletter

New England Osteopathic Heritage Center's annual newsletter for January 2019

Donut Hole Summer 2019, Medicare Donations & Design Committee

Donut Hole Newsletter

No abstract provided.

Donut Hole Summer 2019, Medicare Donations & Design Committee

Donut Hole Newsletter

No abstract provided.

Improvement Academy Annual Report Fy2019, Children's Mercy Kansas City

Improvement Academy Reports and Papers

Children's Mercy Improvement Academy's annual covering the fiscal year 2019 (July 2018-June 2019)

Variability And Stability Of Gait In Stoke Survivors, Jemima Kennedy, Hala Osman

Undergraduate Research Posters 2019

Individuals who have survived a stroke have unstable gait due to poor balance control which jeopardizes the safety of that individual. We analyzed the stability and variability of gait before and after exercise- interventions for individuals who have survived stroke to determine the effect of these interventions on the individual as well as any correlation between measured and perceived stability. 9 randomly assigned participants participated in three exercise interventions: (a) clinical physical therapy, (b) reactive slipping, and (c) video gaming. Kinematics of the participant were obtained using motion analysis and a treadmill equipped with force plates. There was an overall …

Children's Mercy Annual Report 2019, Children's Mercy Hospital

Children's Mercy Annual Reports

Annual report for The Children's Mercy Hospital in Kansas City MO, a pediatric medical center.

Soda Tax Effect On Health Outcomes, Kira Kuwada

Student Research Posters

• Sugar-sweetened beverages (SSBs), also called sugary drinks, are drinks that have added sugar or other sweetener.
• Consumption of SSBs is a risk factor for chronic diseases like diabetes and obesity.
• Food deserts are areas that lack the access to affordable healthy foods and drinks.
• Americans living in food deserts lack essential nutrients in their diets.
• Previous research has shown that SSBs increase the risk for chronic diseases like diabetes, obesity, and cardiovascular disease for all people.
• Previous research has also shown that food deserts is associated to high consumption of SSBs.
• The paper will be a review of the soda …

Flowers Or Flora?: Understanding The Effects Of Probiotics On Depression, Nicole Collopy

Student Research Posters

Chances are, we all know someone who has had their life affected by depression and anxiety; and we have all experienced these feelings on some level. What if the key to unlocking these problems lied within every one of us -- inside of our gut? The research topic being explored is the relationship between gut health and mood disorders. The question of interest is: Does the use of probiotic supplementation have an effect on feelings of depression?

Connection between gut health and mental health is significant as approximately 6.7% of adults in the U.S. suffer from major depressive disorder. There …

Baystate Medical Center Nursing Report - 2019, Christine Klucznik Dnp, Rn

Baystate Medical Center Nursing Report

No abstract provided.

The Innovator - Winter 2019, Allison Litera

Faculty Affairs & Research Newsletters - The Innovator

Quarterly newsletter published by the Offices of Faculty Affairs & Research.