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Full-Text Articles in Medicine and Health Sciences
Evaluation Of Sestrin 2 And Tribbles Homolog 3 Levels In Obese And Nonobese Women With Polycystic Ovary Syndrome, Ayşegül Çatal, Evri̇m Ebru Kovalak
Evaluation Of Sestrin 2 And Tribbles Homolog 3 Levels In Obese And Nonobese Women With Polycystic Ovary Syndrome, Ayşegül Çatal, Evri̇m Ebru Kovalak
Turkish Journal of Medical Sciences
Background/aim: This study was designed to evaluate the relationship of two new biomarkers [tribbles homolog 3 (TRB3) and sestrin 2 levels], which were previously associated with obesity, with metabolic parameters in obese and nonobese women with polycystic ovary syndrome (PCOS). Materials and methods: This cross-sectional case control study was conducted between September 2017 and August 2019 in the gynecology department of a tertiary referral hospital. The values of the plasma sestrin 2, TRB3, insulin, fasting plasma glucose, lipid profile, and homeostasis model assessment of insulin resistance (HOMA-IR) were compared in 90 obese women with PCOS (BMI > 30), 90 women with …
Evaluation Of The Relationship Between Insulin Resistance And Visceral Adiposity Index Inpatients With Acne Vulgaris, İbrahi̇m Fuat Kayihan Kaya, M. Ali̇ Eryilmaz, Selma Pekgör, Orhan Külahci
Evaluation Of The Relationship Between Insulin Resistance And Visceral Adiposity Index Inpatients With Acne Vulgaris, İbrahi̇m Fuat Kayihan Kaya, M. Ali̇ Eryilmaz, Selma Pekgör, Orhan Külahci
Turkish Journal of Medical Sciences
Background/aim: Acne vulgaris (AV) is a chronic inflammatory skin disease that is common among adolescents. Its etiology involves hormones, diet, genetics, and environmental factors. The aim of this study was to investigate the association between acne vulgaris and insulin resistance (IR) and visceral adiposity index (VAI). Materials and methods: The study included 184 individuals. Participants' height, weight, waist and hip circumference and blood pressure were measured. Morning fasting blood was obtained from all participants for measuring glucose, insulin, triglyceride (TG), and cholesterol levels. The HOMA index and visceral adiposity index were calculated. The collected data were analyzed using statistical methods. …
Risk Factors Predicting The Development Of Diabetes Mellitus And Metabolic Syndromefollowing Gestational Diabetes Mellitus, Bülent Can, Sema Çi̇ftçi̇, Gülşah Yeni̇dünya Yalin, Nevi̇n Di̇nççağ
Risk Factors Predicting The Development Of Diabetes Mellitus And Metabolic Syndromefollowing Gestational Diabetes Mellitus, Bülent Can, Sema Çi̇ftçi̇, Gülşah Yeni̇dünya Yalin, Nevi̇n Di̇nççağ
Turkish Journal of Medical Sciences
Background/aim: To determine risk factors associated with the development of insulin resistance, type 2 diabetes mellitus (T2DM), and metabolic syndrome (MetS) in gestational diabetes mellitus (GDM) patients 10 years after giving birth. Materials and methods: Medical records of patients with former GDM were screened. Eligible patients were invited to the hospital to obtain information about their present health status. Patients with pregestational diabetes and patients with multiple pregnancies were excluded. A total of 67 women formed the study group. American Diabetes Association (ADA) and International Diabetes Federation (IDF) criteria were used to define T2DM and MetS, respectively. Results: A total …
Prognostic Role Of Homeostasis Model Assessment And Oral Glucose Tolerance Test Innondiabetic Patients With Bell's Palsy, Tuğba Karagöz, Ömer Bayir, Emel Çadalli Tatar, Erman Çakal, Ali̇ Özdek, Kemal Keseroğlu, Mustafa Şahi̇n, Mehmet Hakan Korkmaz
Prognostic Role Of Homeostasis Model Assessment And Oral Glucose Tolerance Test Innondiabetic Patients With Bell's Palsy, Tuğba Karagöz, Ömer Bayir, Emel Çadalli Tatar, Erman Çakal, Ali̇ Özdek, Kemal Keseroğlu, Mustafa Şahi̇n, Mehmet Hakan Korkmaz
Turkish Journal of Medical Sciences
Background/aim: We aimed to reveal the incidence and predictive role of insulin resistance and distorted oral glucose tolerance test in nondiabetic patients with Bell's Palsy (BP). Materials and methods: Eighty-six patients with BP and 28 control subjects; all with normal blood glucose levels and no history of diabetes, were enrolled in the study. We investigated insulin resistance (IR) in all subjects, in terms of HOMA-IR greater than 2.7. Sixtytwo of the patients also underwent an oral glucose tolerance test (OGTT). Results: The mean HOMA-IR value was significantly increased in patients, compared to the control group (3.2 vs 1.6; P < 0.01). IR was detected more in BP patients than in controls (P < 0.05). The patients with higher HOMA-IR values had more severe facial dysfunction at the initial presentation and complete recovery time took longer than the patients with normal HOMA-IR value (75 days vs 42 days; P < 0.05). Following a 2h-OGTT, impaired glucose tolerance and newly diagnosed DM were found in 60% of the patients. Recovery time was significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia (68 days, 52 days, and 32 days, respectively; P < 0.01). Conclusion: There is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role of predicting BP prognosis at presentation.
The Neutrophil-Lymphocyte Ratio And Its Relationship With Insulin Resistance In Obesity, Serdar Karakaya, Mustafa Altay, Fatma Kaplan Efe, İbrahi̇m Karadağ, Oktay Ünsal, Oktay Bulur, Murat Eser, Derun Taner Ertuğrul
The Neutrophil-Lymphocyte Ratio And Its Relationship With Insulin Resistance In Obesity, Serdar Karakaya, Mustafa Altay, Fatma Kaplan Efe, İbrahi̇m Karadağ, Oktay Ünsal, Oktay Bulur, Murat Eser, Derun Taner Ertuğrul
Turkish Journal of Medical Sciences
In this study, our aim was to investigate the neutrophil/lymphocyte (N/L) ratio, variations in leukocytes and leukocyte subtypes, and the relationship between N/L ratio and insulin resistance (IR) in obesity.Materials and methods: Ninety-six patients and 40 healthy controls were included in this study. Patients' blood glucose levels, insulin levels, and hemogram parameters upon 8 h of fasting were determined. Body mass index (BMI) and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) values were calculated.Results: Neutrophil numbers were found to be higher among obese patients with IR than among non-IR obese patients. The N/L ratio was, moreover, found to be higher among obese …
Positive Correlation Of Galanin With Insulin Resistance And Triglyceride Levels In Obesechildren, Sezer Acar, Ahu Paketçi̇, Tuncay Küme, Korcan Demi̇r, Özlem Gürsoy Çalan, Ece Böber, Ayhan Abaci
Positive Correlation Of Galanin With Insulin Resistance And Triglyceride Levels In Obesechildren, Sezer Acar, Ahu Paketçi̇, Tuncay Küme, Korcan Demi̇r, Özlem Gürsoy Çalan, Ece Böber, Ayhan Abaci
Turkish Journal of Medical Sciences
Background/aim: Galanin is a neuropeptide that is shown to be involved in the regulation of food intake and glucose homeostasis. The objective of this study was to evaluate the relation of serum galanin levels with anthropometric and metabolic parameters in obese and healthy children. Material and methods: The cross-sectional study consisted of 38 obese children (mean age: 11.9 ± 3.0 years) and 30 healthy children (mean age: 11.4 ± 2.0 years). Clinical and biochemical parameters [glucose, insulin, homeostasis model assessment-insulin resistance (HOMA-IR), lipids, galanin, and leptin levels] were assessed. Results: Serum galanin and leptin levels were significantly higher in obese …
The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k
The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Acetylsalicylic acid (ASA) treatment in diabetic patients is very important owing to the increasing hyperactivity of thrombocytes and atherosclerosis. In several investigations, it was reported that diabetes caused increased coronary artery disease, cerebrovascular disease, and death. In this study, we aimed to investigate the effect of ASA on osmoregulation, glycemic control, and some biochemical parameters in rats induced with experimental diabetes type 2. Materials and methods: Twenty-four rats were randomly divided in four groups: control (I), ASA control (II), diabetic (III), and ASA diabetic (IV). Diabetes was induced by streptozotocin treatment (30 mg/kg, twice, intraperitoneal injection) in obese rats. …
Hyperbolic Relation Between Beta-Cell Function And Insulin Sensitivity For Type 2 Diabetes Mellitus, Malaria, Influenza, Helicobacter Pylori, Chlamydia Pneumoniae, And Hepatitis C Virus Infection-Induced Inflammation/Oxidative Stress And Temporary Insulin Resistance In Central Africans, Jean Bosco Kasiam Lasi On'kin, Benjamin Longo-Mbenza, Venant Tchokonte-Nana, Augustin Nge Okwe, Nelly Kangola Kabangu
Hyperbolic Relation Between Beta-Cell Function And Insulin Sensitivity For Type 2 Diabetes Mellitus, Malaria, Influenza, Helicobacter Pylori, Chlamydia Pneumoniae, And Hepatitis C Virus Infection-Induced Inflammation/Oxidative Stress And Temporary Insulin Resistance In Central Africans, Jean Bosco Kasiam Lasi On'kin, Benjamin Longo-Mbenza, Venant Tchokonte-Nana, Augustin Nge Okwe, Nelly Kangola Kabangu
Turkish Journal of Medical Sciences
Background/aim: We calculated the homeostatic model assessment (HOMA) for estimating insulin sensitivity and beta-cell function in normal, healthy nondiabetics with infections (malaria, influenza, HIV, Helicobacter pylori, Chlamydia pneumoniae, and hepatitis C virus), type 2 diabetic black patients, and healthy controls from Kinshasa, DR Congo. Materials and methods: A case-control study was carried out between 2006 and 2007 for black Central African participants managed for HOMA.Results: In total, 219 patients and 110 healthy controls were matched for sex and age. The hyperbolic product for 85 infected patients occupied an intermediate position between the hyperbolic product for 110 controls and that of …
The Relationship Between Blood Urea Nitrogen Levels And Metabolic, Biochemical, And Histopathologic Findings Of Nondiabetic, Nonhypertensive Patients With Nonalcoholic Fatty Liver Disease, Cemal Nuri̇ Erçi̇n, Teoman Doğru, Gürkan Çelebi̇, Hasan Gürel, Hali̇l Genç, Erdi̇m Sertoğlu, Sai̇t Bağci
The Relationship Between Blood Urea Nitrogen Levels And Metabolic, Biochemical, And Histopathologic Findings Of Nondiabetic, Nonhypertensive Patients With Nonalcoholic Fatty Liver Disease, Cemal Nuri̇ Erçi̇n, Teoman Doğru, Gürkan Çelebi̇, Hasan Gürel, Hali̇l Genç, Erdi̇m Sertoğlu, Sai̇t Bağci
Turkish Journal of Medical Sciences
Background/aim: Nonalcoholic fatty liver disease (NAFLD) is known as the most common cause of chronic liver disease. It is accepted that the leading cause of death in patients with NAFLD is from coronary events. Blood urea nitrogen (BUN) was used as a prognostic indicator for cardiovascular disease. We aimed to investigate the relationship between BUN levels and metabolic, biochemical, and histopathologic findings of nondiabetic patients with NAFLD. Materials and methods: A total of 195 male patients with biopsy proven NAFLD and 82 healthy controls with normal liver and renal function tests and normal abdominal ultrasonography were enrolled in the study. …
Insulin-Like Growth Factor 1, Liver Enzymes, And Insulin Resistance In Patients With Pcos And Hirsutism, Evri̇m Çakir, Oya Topaloğlu, Nujen Çolak Bozkurt, Başak Karbek Bayraktar, Aşkin Güngüneş, Müyesser Sayki Arslan, İlknur Öztürk Ünsal, Esra Tutal, Beki̇r Uçan, Tuncay Deli̇başi
Insulin-Like Growth Factor 1, Liver Enzymes, And Insulin Resistance In Patients With Pcos And Hirsutism, Evri̇m Çakir, Oya Topaloğlu, Nujen Çolak Bozkurt, Başak Karbek Bayraktar, Aşkin Güngüneş, Müyesser Sayki Arslan, İlknur Öztürk Ünsal, Esra Tutal, Beki̇r Uçan, Tuncay Deli̇başi
Turkish Journal of Medical Sciences
Hyperinsulinemia and insulin resistance are commonly seen in patients with hirsutism and polycystic ovary syndrome (PCOS), and are associated with cardiovascular disease risk. However, it is not yet known whether insulin-like growth factor I (IGF-I) and alanine transaminase (ALT) produced by the liver play roles in hyperinsulinemia and subclinical atherosclerotic process in patients with PCOS and idiopathic hirsutism (IH). Materials and methods: This was a prospective case-controlled study. The study population consisted of 25 reproductive-age PCOS women, 33 women with IH, and 25 control subjects. Results: Mean IGF-I levels and median ALT levels were higher in patients with IH and …
Endothelial Dysfunction And Insulin Resistance In Young Women With Polycystic Ovarian Syndrome, Mi̇ne Yavuz Taşlipinar, Nedret Kiliç, Ni̇lüfer Bayraktar, İsmai̇l Güler, Yasemi̇n Gülcan Kurt, Tayfun Göktaş, Mehmet Zeki̇ Taner, Mehmet Özdemi̇r Hi̇mmetoğlu, Hali̇l Yaman, Abdullah Taşlipinar
Endothelial Dysfunction And Insulin Resistance In Young Women With Polycystic Ovarian Syndrome, Mi̇ne Yavuz Taşlipinar, Nedret Kiliç, Ni̇lüfer Bayraktar, İsmai̇l Güler, Yasemi̇n Gülcan Kurt, Tayfun Göktaş, Mehmet Zeki̇ Taner, Mehmet Özdemi̇r Hi̇mmetoğlu, Hali̇l Yaman, Abdullah Taşlipinar
Turkish Journal of Medical Sciences
To evaluate whether there is a correlation between insulin resistance and nitric oxide-related endothelial dysfunction in patients with polycystic ovarian syndrome (PCOS). Materials and methods: The study was conducted with 25 young women with PCOS and 25 young healthy women, between 18 and 35 years of age. Plasma asymmetric dimethylarginine (ADMA) levels, serum nitric oxide (NO) levels, and homeostatic model assessment of insulin resistance (HOMA-IR) rates were measured in both the patient and control groups. Results: Plasma ADMA levels were significantly higher in PCOS patients than in the controls (P = 0.001). Serum NO levels were significantly lower in patients …
Is The Combined Use Of Insulin Resistance Indices, Including Adipokines, More Reliable In Metabolic Syndrome?, Bi̇rgül Kural, Orhan Değer, Ci̇hangi̇r Erem, Fulya Balaban Yücesan, Rezzan Ali̇yazicioğlu, Yaşam Barlak
Is The Combined Use Of Insulin Resistance Indices, Including Adipokines, More Reliable In Metabolic Syndrome?, Bi̇rgül Kural, Orhan Değer, Ci̇hangi̇r Erem, Fulya Balaban Yücesan, Rezzan Ali̇yazicioğlu, Yaşam Barlak
Turkish Journal of Medical Sciences
To determine the levels of adipokines (leptin, adiponectin, resistin, and visfatin) and the indices of insulin sensitivity/resistance, and to examine the relationship among them in patients with metabolic syndrome (MetS). Materials and methods: The study groups included 45 subjects with MetS (31 women/14 men), and 45 sex-and age-matched non-MetS healthy volunteers (31 women/14 men). The levels of adipokines were determined by enzyme-linked immunosorbent assay. Results: The levels of leptin and visfatin were significantly higher in the MetS than in the non-MetS subjects (P < 0.01). There was no difference in adiponectin levels in subjects with and without MetS (P = 0.052). Similarly, resistin did not show any statistically significant difference. A statistically significant positive correlation of leptin with insulin levels was observed, while negative correlations of visfatin levels with age, and resistin levels with the ratio of adiponectin to leptin, were found in the MetS (P < 0.05). The combination of adipokines, insulin resistance-sensitivity parameters, and MetS criteria parameters gave more significant differences than a single parameter. Conclusion: Since the parameters mentioned above might affect, interact with, and/or interfere with each other, the combinations of these parameters might give more reliable results to evaluate the insulin resistance/sensitivity in MetS patients.
Insulin Resistance Impairs Response To Doxazosin Therapy In Men With Benign Prostatic Hyperplasia, Cevdet Serkan Gökkaya, Çeti̇n Volkan Özteki̇n, Cüneyt Özden, Emi̇n Öztürk, Bi̇nhan Kağan Aktaş, Ali̇ Memi̇ş
Insulin Resistance Impairs Response To Doxazosin Therapy In Men With Benign Prostatic Hyperplasia, Cevdet Serkan Gökkaya, Çeti̇n Volkan Özteki̇n, Cüneyt Özden, Emi̇n Öztürk, Bi̇nhan Kağan Aktaş, Ali̇ Memi̇ş
Turkish Journal of Medical Sciences
To evaluate the effects of insulin resistance (IR) on outcomes of doxazosin treatment for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Materials and methods: This prospective study included 64 patients with LUTS due to BPH. LUTS were evaluated using the international prostate symptom score (IPSS) and maximum flow rate (Qmax) in uroflowmetry. Diagnosis of IR was achieved using homeostasis model assessment (HOMA) score and patients were grouped with respect to absence (group 1, n = 44) or presence (group 2, n = 20) of IR. Patients were evaluated before and after 3 months of daily doxazosin …
Relation Of Total Homocysteine Level With Metabolic And Anthropometric Variables In Obese Children And Adolescents, Ayhan Abaci, Ahmet Zülfi̇kar Akelma, Osman Özdemi̇r, Şami̇l Hizli, Cem Hasan Razi, Kadi̇r Okhan Akin
Relation Of Total Homocysteine Level With Metabolic And Anthropometric Variables In Obese Children And Adolescents, Ayhan Abaci, Ahmet Zülfi̇kar Akelma, Osman Özdemi̇r, Şami̇l Hizli, Cem Hasan Razi, Kadi̇r Okhan Akin
Turkish Journal of Medical Sciences
To evaluate the total homocysteine (tHcy) level, a risk factor for atherosclerosis, atherothrombosis, and insulin resistance, for sex and pubertal state differences in obese children. Its relationship with metabolic and anthropometric parameters was also investigated. Materials and methods: The study involved obese children with a body mass index (BMI) above the 95th percentile who presented with the complaint of excessive weight gain, and healthy children with a BMI below the 85th percentile. Results: The study included 100 obese (mean age: 10.2 ± 2.7 years) and 71 healthy nonobese (mean age: 10.9 ± 2.6) children. A comparison of the data from …
The Relationship Between Insulin Resistance And Carotid Artery Intima-Media Thickness In Obese And Morbidly Obese Women, Gülçi̇n Cengi̇z Ecemi̇ş, Hakki Kahraman, Mehmet Seli̇m Nural, Hali̇l Serdar Aslan, Ayşegül Atmaca
The Relationship Between Insulin Resistance And Carotid Artery Intima-Media Thickness In Obese And Morbidly Obese Women, Gülçi̇n Cengi̇z Ecemi̇ş, Hakki Kahraman, Mehmet Seli̇m Nural, Hali̇l Serdar Aslan, Ayşegül Atmaca
Turkish Journal of Medical Sciences
To compare insulin resistance and carotid intima-media thickness (IMT) between obese, morbidly obese, and healthy women and demonstrate whether there is a relation between these parameters, focusing mainly on morbidly obese women. Materials and methods: Twenty-five morbidly obese women (body mass index (BMI) => 40 kg/m^²), 25 obese women (BMI 30-39.9 kg/m^²), and 25 age-matched healthy women (BMI 18.5-24.9 kg/m^²) were recruited for the study. None of the subjects had diabetes mellitus. BMI, waist-to-hip ratio, lipid profiles, fasting glucose and insulin levels, insulin resistance (by HOMA), and IMT (common carotid, internal carotid, and bifurcation measurements) were compared among the 3 …
Evaluation Of Vitamin B-12 Level In Middle-Aged Obese Women With Metabolic And Non-Metabolic Syndrome: Case-Control Study, Davut Baltaci, Ali̇ Kutlucan, Serkan Öztürk, İsmai̇l Karabulut, Hayri̇ye Ak Yildirim, Ahmet Çeler, Gökhan Celbek, İsmai̇l Hamdi̇ Kara
Evaluation Of Vitamin B-12 Level In Middle-Aged Obese Women With Metabolic And Non-Metabolic Syndrome: Case-Control Study, Davut Baltaci, Ali̇ Kutlucan, Serkan Öztürk, İsmai̇l Karabulut, Hayri̇ye Ak Yildirim, Ahmet Çeler, Gökhan Celbek, İsmai̇l Hamdi̇ Kara
Turkish Journal of Medical Sciences
To investigate the correlation between vitamin B12 and body mass index (BMI) along with insulin resistance (IR) in middle-aged obese women. Materials and methods: The study was designed as a case-control study. The study group included middle-aged obese women and the control group included aged-matched lean women. Weight, height, and hip and waist circumferences were measured. Biochemical parameters such as fasting and postprandial glucose, vitamin B12 and folic acid levels, and lipid profiles were assayed. Results: Enrolled in the study were 116 middle-aged obese and 103 aged-matched healthy lean women. The vitamin B12 level of the obese women was significantly …
Plasma Adiponectin And Resistin Levels In Women With Polycystic Ovary Syndrome: Relation To Body Mass Index And Insulin Resistance, Emre Di̇kmen, İlhan Tarkun, Funda Öztürk, Berri̇n Arslan, Zeynep Cantürk
Plasma Adiponectin And Resistin Levels In Women With Polycystic Ovary Syndrome: Relation To Body Mass Index And Insulin Resistance, Emre Di̇kmen, İlhan Tarkun, Funda Öztürk, Berri̇n Arslan, Zeynep Cantürk
Turkish Journal of Medical Sciences
To compare the serum levels of adiponectin and resistin between patients with polycystic ovary syndrome (PCOS) and healthy control subjects matched for age and body mass index (BMI), and to assess possible correlations of adiponectin and resistin to the hormonal and metabolic parameters of the syndrome. Materials and methods: Fifty five patients with PCOS diagnosis composed of 25 obese, 13 overweight, 17 normal weight subjects, and 49 healthy women matched for age and BMI were included in this study. Hormone and lipid profile, adiponectin, and resistin were measured in all cases. Results: Serum adiponectin levels were similar in the lean …
Metabolic Profile And Insulin Resistance In Patients With Obstructive Sleep Apnea Syndrome, Mustafa Şahi̇n, Berri̇n Berçi̇k İnal, Şahi̇n Öğreden, Özgür Yi̇ği̇t, Hale Aral, Güvenç Güvenen
Metabolic Profile And Insulin Resistance In Patients With Obstructive Sleep Apnea Syndrome, Mustafa Şahi̇n, Berri̇n Berçi̇k İnal, Şahi̇n Öğreden, Özgür Yi̇ği̇t, Hale Aral, Güvenç Güvenen
Turkish Journal of Medical Sciences
The following metabolic parameters were assessed in patients with obstructive sleep apnea syndrome (OSAS) diagnosed by polysomnography (PSG): leptin, IFG (ımpaired fasting glucose), thyroid functions, thyroid autoantibodies, lipid parameters, insulin levels, HOMA-IR index, CRP, obesity, and metabolic syndrome frequency. Materials and methods: Three patient groups were defined based on apnea-hypoapnea index (AHI) levels (Group I: n: 11 male (M)/19 female (F); Group II: n: 19 M/10 F; Group III: n: 21 M/10 F) and 2 control groups (obese (n = 18 M/12 F) and normal (n = 12 M/18 F)) were included with comparable BMI value and age. Results: The …
The Association Of Tafi (Thrombin-Activatable Fibrinolysis Inhibitor) With Insulin Resistance And Components Of Metabolic Syndrome In Patients With Metabolic Syndrome, Alev Kural, Ahmet Omma, Hati̇ce Seval, Maci̇t Koldaş, Namik Yi̇ği̇t, Tülay Omma
The Association Of Tafi (Thrombin-Activatable Fibrinolysis Inhibitor) With Insulin Resistance And Components Of Metabolic Syndrome In Patients With Metabolic Syndrome, Alev Kural, Ahmet Omma, Hati̇ce Seval, Maci̇t Koldaş, Namik Yi̇ği̇t, Tülay Omma
Turkish Journal of Medical Sciences
To investigate the association of TAFI with components of metabolic syndrome and insulin resistance in patients with metabolic syndrome. Materials and methods: Patients between 20 and 70 years of age, who met at least 3 of the metabolic syndrome criteria, and had no known coronary artery disease were included in the study. The control group consisted of 20 healthy subjects with demographic characteristics similar to the patients. Fasting blood glucose, HbA1c, lipid profile, insulin, microalbumin, and TAFI Ag levels were investigated in the patients and controls. Insulin resistance was calculated according to the HOMA-IR [(fasting plasma insulin (\muIU/ml) x fasting …
The Role Of Ultrasonographic Hepatic Artery Resistive Index In The Diagnosis Of Insulin Resistance In Obese Children With Non-Alcoholic Fatty Liver Disease, Şami̇l Hizli, Ali̇ Koçyi̇ği̇t, Nur Arslan, Sedat Alpaslan Tuncel, Fati̇h Demi̇rci̇oğlu, Handan Çakmakçi, Benal Büyükgebi̇z
The Role Of Ultrasonographic Hepatic Artery Resistive Index In The Diagnosis Of Insulin Resistance In Obese Children With Non-Alcoholic Fatty Liver Disease, Şami̇l Hizli, Ali̇ Koçyi̇ği̇t, Nur Arslan, Sedat Alpaslan Tuncel, Fati̇h Demi̇rci̇oğlu, Handan Çakmakçi, Benal Büyükgebi̇z
Turkish Journal of Medical Sciences
To determine the role of hepatic artery resistive index (HARI) measurement in the prediction of insulin resistance (IR) in obese children with nonalcoholic fatty liver disease (NAFLD). Materials and methods: A total of 64 obese subjects with NAFLD (13.5 ± 1.36 years of age, 34 male) and 32 age- and gender-matched control subjects (13.8 ± 1.24 years of age, 16 male) were enrolled in the study. All subjects underwent a physical examination, laboratory tests, and ultrasonographic and Doppler examinations of the liver. The homeostasis model assessment of IR (HOMA-IR) was used for the IR diagnosis. Results: Obese subjects with NAFLD …
Serum Leptin, Lipoprotein Levels, And Glucose Homeostasis Between National Wrestlers And Sedentary Males, Faruk Yamaner, Taner Bayraktaroğlu, Hulusi̇ Atmaca, Mehmet Aki̇f Zi̇yagi̇l, Kemal Tamer
Serum Leptin, Lipoprotein Levels, And Glucose Homeostasis Between National Wrestlers And Sedentary Males, Faruk Yamaner, Taner Bayraktaroğlu, Hulusi̇ Atmaca, Mehmet Aki̇f Zi̇yagi̇l, Kemal Tamer
Turkish Journal of Medical Sciences
Leptin is an important controller of the size of fat stores by inhibiting appetite. In wrestling, fat metabolism is important not only for aerobic energy system, but also for weight control and weight loss before competition. The aim of this study was to measure and compare the serum leptin levels, glucose homeostasis, and serum lipoproteins between Turkish national wrestlers and sedentary males. Materials and methods: Forty-five Turkish national wrestlers at the end of Olympic training camp before Beijing 2008 Olympic Games and 43 sedentary students were selected as subjects. Post-exercise levels of serum leptin, HOMA (Homeostasis model assessment) values, triglycerides, …
The Effects Of Insulin On Serum Levels Of Apo A-I Containing Lipoprotein Particles In Syndrome X Patients With Coronary Heart Disease, Meti̇n Yildirimkaya, Cumhur Kilinç, Mustafa Özkan, Kurtuluş Yilmaz, Yavuz Nari̇n
The Effects Of Insulin On Serum Levels Of Apo A-I Containing Lipoprotein Particles In Syndrome X Patients With Coronary Heart Disease, Meti̇n Yildirimkaya, Cumhur Kilinç, Mustafa Özkan, Kurtuluş Yilmaz, Yavuz Nari̇n
Turkish Journal of Medical Sciences
Syndrome X consists of low serum high density lipoprotein-cholesterol (HDL-C), raised serum triglyceride, glucose intolerance, increased blood pressure, abdominal obesity and insulin resistance which is associated with increased risk of coronary heart disease (CHD). Apolipoprotein (apo) A-I containing lipoprotein particles, lipoprotein A-I (Lp A-I) and lipoprotein A-I:A-II (Lp A-I:A-II.) may have different metabolic functions. The purpose of this study was to evaluate the relationship between insulin and apo A-I containing lipoproteins in syndrome X patients with or without CHD. We selected 38 male patients with syndrome X and divided into two groups: The one with CHD (n=21) and the other …