Medicine and Health Sciences Commons^™

The Effects Of Sglt2 Inhibitors In Patients With Metabolic Dysfunction-Associated Fatty Liver Disease; A Narrative Review, Mihaela Simona Popoviciu, Lorena Paduraru, Mominur Rahman, Fatema Akter Supti, Roxana Adriana Stoica, Delia Reurean Pintilei, Cristina Ioana Bica, Simona Cavalu

Journal of Mind and Medical Sciences

Worldwide, metabolic dysfunction-associated fatty liver disease (MAFLD) is a significant public health concern, especially since more than fifty percent of people with type 2 diabetes are affected by it. This pathological condition includes all states of fatty liver disease, from non-alcoholic fatty liver disease (NAFLD) to steatohepatitis (NASH). Prolonged evolutions can lead to cirrhosis and cancer, so treatment must be started early. Hepatic steatosis may be improved by sodium glucose co-transporter 2 inhibitors (SGLT2 inhibitors), which prevent glucose reabsorption in the proximal renal tubule and increase urinary excretion, thus lowering plasma glucose levels. Experimental studies in animal models have suggested …

Most Common Symptoms Of Prediabetic And Insulin Resistance In Adults In Saudi Arabia, Hassan Mazzhar Bukhari, Fatoon Mohammed Albuqami, Alanoud Mohammed Asiri, Ghadeer Othman Yatim, Jomana Abdullah Alshareef, Ruba Saeed Alzahrani

Makara Journal of Health Research

Background: The prediabetic stage exhibits common symptoms; hence, the risk of developing diabetes can be reduced by identifying these symptoms in the most affected population. This study aimed to examine the prevalence of the main symptoms of insulin resistance in healthy adults aged 18 years and above.

Methods: A cross-sectional study was conducted on 1,514 Saudi adults using an online questionnaire collected from 13th November 2020 to 23rd March 2021. Data on personal, lifestyle, and common symptoms were gathered, and the main symptoms were presented as frequencies with percentages. Association with insulin resistance was evaluated using the Chi-square …

Relationship Between Non-Alcoholic Steatohepatitis And Left Ventricular Diastolic Dysfunction In Type 2 Diabetic Patients, Alaa Eldin A. Dawood, Mervat A. Mostafa, Wessam E. El-Shafey, Esraa N. Abo El-Rous, Shimaa K. Zewain

Menoufia Medical Journal

Objectives: To determine if the poor diastolic function of the left ventricle was independently correlated with hepatic steatosis and fibrosis in type 2 diabetes mellitus (T2DM). Background: There is growing evidence that it is related to nonalcoholic fatty liver disease (NAFLD) and left ventricular diastolic dysfunction (LVDD). We sought to learn more about the relationship between LV diastolic dysfunction and liver fibrosis in T2DM patients. Methods: a case control study was conducted on 100 patients, 50 of them with type 2 diabetes patients without NAFLD and 50 diabetic patients with NAFLD. NAFLD fibrosis score (NFS) and abdominal ultrasonography were used …

Evaluation Of Sestrin 2 And Tribbles Homolog 3 Levels In Obese And Nonobese Women With Polycystic Ovary Syndrome, Ayşegül Çatal, Evri̇m Ebru Kovalak

Turkish Journal of Medical Sciences

Background/aim: This study was designed to evaluate the relationship of two new biomarkers [tribbles homolog 3 (TRB3) and sestrin 2 levels], which were previously associated with obesity, with metabolic parameters in obese and nonobese women with polycystic ovary syndrome (PCOS). Materials and methods: This cross-sectional case control study was conducted between September 2017 and August 2019 in the gynecology department of a tertiary referral hospital. The values of the plasma sestrin 2, TRB3, insulin, fasting plasma glucose, lipid profile, and homeostasis model assessment of insulin resistance (HOMA-IR) were compared in 90 obese women with PCOS (BMI > 30), 90 women with …

“Cost-Effective Markers To Identify Metabolically Healthy/Unhealthy Individuals And Their Future Risk For Cardiovascular Disorders”, Shobha C Ramachandra, Akila Prashant, Akshitha Shivanna, Ananth Koushik Bhujanga, Syeda Meherunnisa, Prashant Vishwanath

International Journal of Health and Allied Sciences

Background: With the rising prevalence of metabolically healthy obese, it becomes essential to identify markers to differentiate them from metabolically unhealthy obese and their future risk for cardiovascular disorders (CVD). The study aims to identify suitable markers for risk stratification of metabolically healthy/unhealthy individuals and their risk for CVD. Method: Total 84 individuals aged 18-60 years of age without any comorbidities were enrolled. Their demographic details along with anthropometric measurements were noted. The biochemical parameters like fasting glucose, insulin, lipid profile, and serum adipokines were estimated. Insulin resistance (IR) markers and atherogenic indices were calculated. The data were analyzed on …

New Onset, Refractory Hyperglycemia With Diabetic Ketoacidosis After Enfortumab Vedotin Treatment: A Case Report, Ross E. Heinrich, Marie Caldwell

Journal of Maine Medical Center

Introduction: A patient with no prior diagnosis of diabetes presented with diabetic ketoacidosis (DKA) and severe insulin resistance after being treated with enfortumab vedotin (EV). EV-associated DKA is uncommon—described in only a few case reports—and has unknown pathophysiology. This case characterizes the unique features of DKA in this patient and an unusual amount of insulin resistance not typically seen in patients with diabetes.

Clinical Findings: A 71-year-old male presented with fatigue, xerostomia, and increased thirst. He had a history of obesity, hypertension, and invasive, high-grade papillary urothelial carcinoma. His laboratory results were consistent with DKA.

Clinical Course: The patient was …

Does Insulin Resistance (Ir) Have An Impact On The Reproductive And Fertility Potential In Polycystic Ovary Syndrome (Pcos) Women? : Review Article, Muhjah Falah Hassan, Mufedah Ali Jawad, Rabab Zahir Al-Yasiry

Maaen Journal for Medical Sciences

Backgrounds: Polycystic ovary syndrome is the most common endocrine and reproductive disorder in the reproductive-age women. Among the pathological changes that are responsible for the development of polycystic ovary syndrome (PCOS), hyperinsulinemia due to increased insulin resistance (IR) is common and usually associated with a higher rate of ovulatory dysfunction and sub-fertility. In addition, those women have poor quality oocytes with low fertilization capability and poor quality embryos. So, insulin has a role in the reproductive function and fertility potential of reproductive age women. Conclusion: Females with PCOS usually exhibit an extreme difficulty in achieving either a successful spontaneous or …

Postprandial And Fasting Lipopolysaccharide Levels In Healthy Hispanic Residents Of Southeast Texas With Positive Family History Of Type 2 Diabetes, Amanda J. Wheeler, Yu Lun Tai, Smaran Marupudi, Ryan D. Russell

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Healthy people with a family history (FH+) of type 2 diabetes (T2D) display impaired metabolic and microvascular function prior to glucose intolerance, and are at greater risk for developing T2D. While mechanisms to explain this disparity are lacking, it is possible that intestinal permeability plays a role, as it is also linked with insulin resistance, glucose intolerance, and chronic inflammation. Lipopolysaccharides (LPS) act as an outer membrane component of gram-negative bacteria in intestines and play a role in inflammation and chronic disease when in circulation, thus serving as a surrogate measure of intestinal permeability. However, the link between FH+ …

First Trimester Metformin In Polycystic Ovary Syndrome Patients With History Of Recurrent Early Pregnancy Loss: Randomized Controlled Trial, Farid Ibrahim Hassan, Muhamed Ahmed Abdelmoaty, Ahmed Hamdy Muhammed Saad

Al-Azhar International Medical Journal

Background: Women with polycystic ovarian syndrome (PCOS) who take metformin throughout their pregnancies have lower rates of miscarriage, labour, and foetal development restriction. Positive benefits of metformin on insulin sensitivity, plasma glucose concentration, and lipid profile have been shown in patients with polycystic ovary syndrome.

Aim and objectives: to the disparity in the occurrence of miscarriage between two patient cohorts who will get or not receive Metformin in the first trimester, to determine the efficacy of Metformin in preventing early pregnancy loss in pregnant patients with PCOs.

Subjects and methods: This was a randomised controlled trial that was conducted on …

Assessment Of Serum Irisin And Its Relation To Insulin Resistance In Patients With Acne Vulgaris, Asmaa A M. Ali, Magda M. Hagag, Sherin S. El Sayed Al Naidany

Menoufia Medical Journal

Objective The aim of the present study was to evaluate serum irisin, in addition to fasting insulin and fasting blood glucose levels in patients with acne vulgaris (AV), and assessment of its clinical significance and relation to insulin resistance (IR). Background AV is recognized as an almost universal cutaneous disease, the third most prevalent skin disease worldwide, with the highest prevalence among adolescents, ranging between 40 and 70%. Patients and methods This study was conducted on 40 patients suffering from AV (group A) and 40 healthy individuals of matched age and sex as a control group (group B). Serum irisin …

Validity Of New Insulin Resistance Indices In Correlation With Atherosclerotic Cardiovascular Disease, Ahmed M. Mohamed, Mai A. Kamel, Nabil Abd El-Fatah El-Kafrawy, Reham S. El Zaiat

Menoufia Medical Journal

Objective To study the validity of triglyceride–glucose (TyG) index and triglyceride/high-density lipoprotein (TG/HDL) ratio as insulin resistance (IR) markers and correlating them with atherosclerotic cardiovascular disease (ASCVD). Background IR is a metabolic disorder that leads to metabolic syndrome, which is an important risk factor for ASCVD; early detection by noninvasive, easy and cheap markers is important. Patients and methods A cross-sectional study carried out on 81 participants attending to the outpatient clinic and inpatient ward in the Internal Medicine Department. Full history, physical examination, and biochemical profiles were obtained. Participants were classified according to the Framingham Wilson score into two …

Metabolic Risk Assessment In Women With Hirsutism, Ahmed M. Hamam, Nesma A. Ibrahim

Menoufia Medical Journal

Objective To assess the presence of metabolic risk in women with hirsutism and to determine if the site of hirsutism can be a predictor of metabolic syndrome. Background Polycystic ovary syndrome (PCOS) and idiopathic hirsutism (IH) are the most common causes of hirsutism. Patients and methods A total of 90 women were included. They were divided into group 1, which included 30 women with IH; group 2, which included 30 women with PCOS; and group 3, which included 30 healthy women representing a control group. Participants underwent examination including hirsutism assessment and investigations, including fasting plasma glucose, fasting insulin, and …

The Impact Of Circuit Resistance Training On Serum Glucose, Insulin Resistance And Health Related Physical Fitness In Elderly Men With Type 2 Diabetes, Hamid Arazi, Roghayeh Gholizadeh, Amin Sohbatzadeh, Ehsan Eghbali

Baltic Journal of Health and Physical Activity

Background: Obesity and decreased physical activity are the most important factors in the development of type 2 diabetes, which in recent decades has led to an increase in the number of people with this disease. The aim of this study was to investigate the impact of circuit resistance training (CRT) on serum glucose, insulin resistance and health related physical fitness in elderly men with type 2 diabetes. Material and methods: Twenty-two patients with type 2 diabetes (60.99 ±2.93 years) volunteered to participate in this study. They were divided randomly into two groups: training (n = 11) and control (n = …

Evaluation Of The Relationship Between Insulin Resistance And Visceral Adiposity Index Inpatients With Acne Vulgaris, İbrahi̇m Fuat Kayihan Kaya, M. Ali̇ Eryilmaz, Selma Pekgör, Orhan Külahci

Turkish Journal of Medical Sciences

Background/aim: Acne vulgaris (AV) is a chronic inflammatory skin disease that is common among adolescents. Its etiology involves hormones, diet, genetics, and environmental factors. The aim of this study was to investigate the association between acne vulgaris and insulin resistance (IR) and visceral adiposity index (VAI). Materials and methods: The study included 184 individuals. Participants' height, weight, waist and hip circumference and blood pressure were measured. Morning fasting blood was obtained from all participants for measuring glucose, insulin, triglyceride (TG), and cholesterol levels. The HOMA index and visceral adiposity index were calculated. The collected data were analyzed using statistical methods. …

Pharmacotherapy For Non-Alcoholic Steatohepatitis - Current Status And Future Prospects, Ganesh Bhat

Manipal Journal of Medical Sciences

Non-alcoholic Steatohepatitis (NASH) is emerging as a leading cause of cirrhosis worldwide. Weight reduction through lifestyle modification is accepted first line treatment for these patients. Histological improvement in highrisk patient is the primary target of pharmacotherapy in NASH patients. Even though currently many drugs are available for these high-risk patients, none of them has been approved USA Food and Drug Administration (FDA) until now. Among these, vitamin E and pioglitazone has been approved by AASLD (American Association for the Study of Liver Diseases) in selected group of patients. There are more than a dozen drug targeting different pathways in NASH …

Inflammation, Oxidative Stress, Insulin Resistance, And Hypertension As Mediators For Adverse Effects Of Obesity On The Brain: A Review, Mahnaz Ghowsi, Farshad Qalekhani, Mohammad Hosein Farzaei, Fariba Mahmudi, Namdar Yousofvand, Tanuj Joshi

BioMedicine

Nowadays, the incidence of obesity is a global challenge and it is estimated that the total number of overweight and obese adults will increase up to 1.35 billion by 2030. Evidence obtained from clinical and experimental studies shows that obesity may be associated with cognitive performance and executive function impairments. Considering various evidence for the poor episodic memory tasks and verbal learning as well as the destruction of cortical gray matter in the obese individuals, here, we collected some causal pathways for contribution of inflammation, oxidative stress, insulin resistance, and hypertension in the development of brain disorders in obesity. The …

The Role Of Physical Activity In The Relationship Between Sitting Time And Insulin Resistance, Kayla Parker, Larry A. Tucker

International Journal of Exercise Science: Conference Proceedings

PURPOSE: The primary objective of the present study was to determine the role of physical activity in the relationship between sitting time and insulin resistance in 7,092 randomly selected U.S. adults. METHODS: Cross-sectional data from the National Health and Nutrition Examination Survey (NHANES), 2011-2018, were used to answer the research question. NHANES data for 2019-2020 were not available because of COVID. Participants were selected using a multi-stage, random sampling strategy. Subjects reported average sitting time, quantified as the number of minutes spent per day sitting. Insulin resistance was determined using HOMA-IR (homeostatic model assessment). HOMA-IR is the most common measure …

Association Among Insulin Receptor Substrate1 Genetic Polymorphism, Sulfonylurea Therapeutic Efficacy, And Insulin Resistance In Patients With Type 2 Diabetes Mellitus, Ayat I. Ghanem, Ghada A. Omar, Wafaa S. Hegab

Journal of Medicine in Scientific Research

Background Insulin receptor substrate-1 gene (IRS-1) is an endogenous substrate of the insulin receptor present in insulin-sensitive tissues, allowing insulin signaling to take place. The IRS-1, rs1801278 gene with Gly972Arg substitution polymorphism is one of the most commonly studied variants in relation with type 2 diabetes mellitus (T2DM). Objective The objective of this study was to detect the genetic association of the IRS-1, rs1801278 gene polymorphism with secondary sulfonylurea (SU) failure and insulin resistance (IR) in T2DM in Egyptian patients. Patients and methods A total of 81 T2DM Egyptian patients (49 nonresponders and 32 responders to SU) were recruited. Genotyping …

The Crosstalk Between Insulin Resistance, Systemic Inflammation, Redox Imbalance And The Thyroid In Subjects With Obesity, Nicoleta Răcătăianu, Nicoleta Valentina Leach, Sorana D. Bolboacă, Maria Loredana Soran, Mirela Flonta, Ana Valea, Andrada-Luciana Lazăr, Cristina Ghervan

Journal of Mind and Medical Sciences

We aimed at assessing the interaction between visceral adipose tissue (VAT), insulin resistance (IR), circulating levels of monocyte chemoattractant protein-1 (MCP-1) and malondialdehyde (MDA) and the thyroid parameters in obese subjects. Methods. Obese subjects without thyroid pathologies or diseases associated with systemic inflammation and OS were recruited. Insulinemia, visceral fat thickness, metabolic and thyroid parameters were assayed. Circulating levels of MCP-1 and MDA were used to quantify inflammation and OS. Results. A number of 160 obese subjects were included. The MCP-1 level increased with the degree of obesity and HOMA-IR. MCP 1 was positively associated with antithyroperoxidase antibody (TPOab) levels …

Correlation Between Metabolic Syndrome And Benign Prostatic Hyperplasia, Abd Allah M. Attia, Haitham M. Abdelaal, Hossam A. Yasien, Mohamed S.M. Elgharbawy

Menoufia Medical Journal

Objective To study the relation between metabolic syndrome (MetS) and benign prostatic hyperplasia (BPH). Background BPH is the most common urological condition among elderly males, with multiple etiopathogenesis. Patients and methods This prospective study was carried out on 90 male individuals aged 45–60 years classified into three groups: group 1 included 30 normal male individuals who had neither MetS nor BPH, group 2 included 30 patients with diagnosed BPH, and group 3 included 30 patients with diagnosed criteria of MetS. Results The study showed that compared with the control group, MetS group has significant higher manifestations of BPH with its …

Risk Factors Predicting The Development Of Diabetes Mellitus And Metabolic Syndromefollowing Gestational Diabetes Mellitus, Bülent Can, Sema Çi̇ftçi̇, Gülşah Yeni̇dünya Yalin, Nevi̇n Di̇nççağ

Turkish Journal of Medical Sciences

Background/aim: To determine risk factors associated with the development of insulin resistance, type 2 diabetes mellitus (T2DM), and metabolic syndrome (MetS) in gestational diabetes mellitus (GDM) patients 10 years after giving birth. Materials and methods: Medical records of patients with former GDM were screened. Eligible patients were invited to the hospital to obtain information about their present health status. Patients with pregestational diabetes and patients with multiple pregnancies were excluded. A total of 67 women formed the study group. American Diabetes Association (ADA) and International Diabetes Federation (IDF) criteria were used to define T2DM and MetS, respectively. Results: A total …

Insulin Resistance As A Noninvasive Predictor Of Esophageal Varices In Hepatitis C Virus Cirrhotic Patients, Ahmed R. El-Gazzarah, Atef A. Ali, Belal A. Montaser, Heba G. Abdel-Fattah

Menoufia Medical Journal

Objectives The aim was to evaluate sensitivity and specificity of insulin resistance (IR) as a noninvasive predictor of esophageal varices (EV) in hepatitis C virus (HCV) cirrhotic patients. Background Variceal bleeding due to portal hypertension is associated with a high probability of circulatory dysfunction and even death. However, routine endoscopy is an invasive maneuver which consumes effort, time, and money. IR was studied as an early noninvasive predictor of EV. Patients and methods Eighty cirrhotic patients were included in this prospective case–control study and 20 nondiabetic nonhepatic patients served as the control group. Patients were recruited from the Gastrointestinal Endoscopy …

Metabolic Profile And Adipokine Levels In Overweight And Obese Dogs, Paula Nassar De Marchi, Luiz Henrique Araújo Machado, Luciane Holsback, Jessica Ragazzi Calesso, Rafael Fagnani, Ademir Zacarias Junior, Mauro Jose Lahm Cardoso

Turkish Journal of Veterinary & Animal Sciences

Obesity in dogs is increasingly present in the veterinary practice. In humans, it is known that there is a significant correlation between obesity and the development of hypertension and insulin resistance (IR), a clinical picture called metabolic syndrome. In dogs, however, there are only anecdotes about the syndrome. The objectives of this study were to determine serum levels of adiponectin, leptin, triglycerides, cholesterol, insulin, glucose, homeostasis assessment of B cell function (HOMA-B), homeostasis assessment of insulin resistance (HOMA-IR), and systolic blood pressure (SBP) in dogs with different body conditions (BC) and body fat (BF) without endocrine disease. For this purpose, …

Prognostic Role Of Homeostasis Model Assessment And Oral Glucose Tolerance Test Innondiabetic Patients With Bell's Palsy, Tuğba Karagöz, Ömer Bayir, Emel Çadalli Tatar, Erman Çakal, Ali̇ Özdek, Kemal Keseroğlu, Mustafa Şahi̇n, Mehmet Hakan Korkmaz

Turkish Journal of Medical Sciences

Background/aim: We aimed to reveal the incidence and predictive role of insulin resistance and distorted oral glucose tolerance test in nondiabetic patients with Bell's Palsy (BP). Materials and methods: Eighty-six patients with BP and 28 control subjects; all with normal blood glucose levels and no history of diabetes, were enrolled in the study. We investigated insulin resistance (IR) in all subjects, in terms of HOMA-IR greater than 2.7. Sixtytwo of the patients also underwent an oral glucose tolerance test (OGTT). Results: The mean HOMA-IR value was significantly increased in patients, compared to the control group (3.2 vs 1.6; P < 0.01). IR was detected more in BP patients than in controls (P < 0.05). The patients with higher HOMA-IR values had more severe facial dysfunction at the initial presentation and complete recovery time took longer than the patients with normal HOMA-IR value (75 days vs 42 days; P < 0.05). Following a 2h-OGTT, impaired glucose tolerance and newly diagnosed DM were found in 60% of the patients. Recovery time was significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia (68 days, 52 days, and 32 days, respectively; P < 0.01). Conclusion: There is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role of predicting BP prognosis at presentation.

Visceral Adiposity And Insulin Resistance In The Prediction Of Gestational Diabetes Mellitus In Early Pregnancy: A Prospective Observational Study, Abeer E. Abo El-Fetouh, Alaa E. Elahalaby, Ibrahim Saif Elnasr, Osama A. Elkelani

Menoufia Medical Journal

Objective The aim was to study the relationship between abdominal adiposity and insulin resistance in the prediction of gestational diabetes mellitus (GDM) in early pregnancy. Background There is a positive association between high prepregnancy BMI and risk of GDM. Patients and methods This prospective cohort study included 83 women at 11–14 weeks for abdominal adiposity measurement and at 16–22 weeks for oral glucose tolerance test measurement. The patients were divided into two groups: group 1included patients who did not develop GDM and group 2included patients who developed GDM. This study was conducted at the Obstetrics and Gynecology Department, Menoufia University …

The Neutrophil-Lymphocyte Ratio And Its Relationship With Insulin Resistance In Obesity, Serdar Karakaya, Mustafa Altay, Fatma Kaplan Efe, İbrahi̇m Karadağ, Oktay Ünsal, Oktay Bulur, Murat Eser, Derun Taner Ertuğrul

Turkish Journal of Medical Sciences

In this study, our aim was to investigate the neutrophil/lymphocyte (N/L) ratio, variations in leukocytes and leukocyte subtypes, and the relationship between N/L ratio and insulin resistance (IR) in obesity.Materials and methods: Ninety-six patients and 40 healthy controls were included in this study. Patients' blood glucose levels, insulin levels, and hemogram parameters upon 8 h of fasting were determined. Body mass index (BMI) and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) values were calculated.Results: Neutrophil numbers were found to be higher among obese patients with IR than among non-IR obese patients. The N/L ratio was, moreover, found to be higher among obese …

Elevated Homeostatic Model Assessment Of Insulin Resistance Level Increases The Risk Of Acne, Stefani Nurhadi, Igaa Praharsini, Aagp Wiraguna

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Insulin resistance and high carbohydrate diets are currently considered to be influential in acne aetiology. Insulin is a hormone that does not only regulate the concentration of blood glucose but also affects the production of sebum and through the Insulin Growth Factor-1 (IGF-1) receptor stimulates androgen synthesis which will increase the proliferation of keratinocytes duct and the production of sebum in acne of the pilosebaceous.

Methods: This is a cross sectional observational analytic study involving 38 acne patients and 38 controls. This study aims to determine whether the increase in Homeostatic Model Assessment of Insulin Resistance …

Unhealthy Lifestyle And The Risk Of Metabolic Syndrome- The Romanian Experience, Angela Cozma, Adela Sitar-Taut, Laura Urian, Adriana Fodor, Ramona Suharoschi, Crina Muresan, Vasile Negrean, Dorel Sampelean, Dumitru Zdrenghea, Dana Pop, Leucuta Daniel, Olga Hilda Orasan

Journal of Mind and Medical Sciences

Background. Metabolic syndrome (MetS) represents a clustering of metabolic risk factors for cardiovascular disease. Many studies have shown the influence of an unhealthy lifestyle on the risk of MetS, yet some aspects remain controversial. Aim of the study: to investigate the relationship between an unhealthy lifestyle and the risk of MetS.

Materials and Methods. The study was conducted using a sample of 181 patients, 54 (29.8%) males and 127 (70.2%) females, aged 59.95±10.8 years. The baseline survey involved the completion of structured questionnaires and clinical examination.

Results. Rural environment, lower education level, past smoking, the absence of fruit/vegetables in the …

Epidemiology Of Metabolic Syndrome In Menoufia University Students, Ghadeer M.M El Sheikh, Hewaida M. Anwar El Shazly, Omaima A. Mahrous, Reda A. Ibraheem, Safaa A. Badr, Zeinab A. Kasemy, Mahmood D. Al-Mendalawi

Menoufia Medical Journal

Objective

The aim was to assess the prevalence of metabolic syndrome (MetS) and its associated risk factors in Menoufia University students. Background

MetS is a growing public health concern worldwide. The rapid sociocultural transition associated with major changes in lifestyle and eating habits has been claimed for the rising rates of MetS among young adults and children, which is the leading cause of developing type II diabetes and cardiovascular diseases. Participants and Methods

A cross-sectional study was conducted during the academic year 2016/2017 at Menoufia University on 455 university students aged 18–25 years. The students were chosen from four faculties …

A Family History Of Type 2 Diabetes May Impair Glucose Area Under The Curve In Young, Healthy Hispanics, Cesar Meza, Manuel Amador, Mario Garcia, Christopher Figueroa, Andrew Mcainch, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

Obesity and type 2 diabetes are associated with impaired glucose homeostasis and blood lipid profiles. Further, a family history of diabetes (FH) increases the risk for development of insulin resistance. However, it is unclear whether a FH impairs glucose tolerance, blood glucose and lipid profiles in young, healthy, normoglycemic adults. PURPOSE: To investigate whether a FH impairs glucose tolerance and blood lipid profile in healthy, sedentary Hispanic males. METHODS: 22 sedentary, normoglycemic, Mexican American males (mean±SEM: age:23±0.56 yrs; BMI: 26.9±0.98 kg/m²) with/without FH participated in the study. Glucose tolerance was assessed by calculating glucose area under …