Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- COVID-19 (18)
- Prognosis (7)
- Children (6)
- Mortality (6)
- Oxidative stress (6)
-
- Magnetic resonance imaging (5)
- Vitamin D (5)
- Atrial fibrillation (4)
- Breast cancer (4)
- Treatment (4)
- Type 2 diabetes mellitus (4)
- Biomarker (3)
- COPD (3)
- Chronic obstructive pulmonary disease (3)
- Diagnosis (3)
- Familial Mediterranean fever (3)
- Ferritin (3)
- Frailty (3)
- Inflammation (3)
- Interstitial lung disease (3)
- Metastasis (3)
- Primary hyperparathyroidism (3)
- SARS-CoV-2 (3)
- Turkey (3)
- Anakinra (2)
- Anti-TNF (2)
- Bronchoscopy (2)
- Chemotherapy (2)
- Chronic pain (2)
- Colorectal cancer (2)
Articles 31 - 60 of 238
Full-Text Articles in Medicine and Health Sciences
Causes Of Severe Infections In Patients With Systemic Sclerosis And Associated Factors, Müçteba Enes Yayla, Emi̇ne Uslu Yurteri̇, Murat Torğutalp, Di̇dem Şahi̇n Eroğlu, Serdar Sezer, Ayşe Bahar Keleşoğlu Di̇nçer, Emi̇ne Gözde Aydemi̇r Gülöksüz, Mehmet Levent Yüksel, Recep Yilmaz, Aşkin Ateş, Tahsi̇n Murat Turğay, Gülay Kinikli
Causes Of Severe Infections In Patients With Systemic Sclerosis And Associated Factors, Müçteba Enes Yayla, Emi̇ne Uslu Yurteri̇, Murat Torğutalp, Di̇dem Şahi̇n Eroğlu, Serdar Sezer, Ayşe Bahar Keleşoğlu Di̇nçer, Emi̇ne Gözde Aydemi̇r Gülöksüz, Mehmet Levent Yüksel, Recep Yilmaz, Aşkin Ateş, Tahsi̇n Murat Turğay, Gülay Kinikli
Turkish Journal of Medical Sciences
Background/aim: Systemic sclerosis (SSc) is a chronic systemic disease characterized by vascular damage, autoimmunity, and fibrosis in the skin and internal organs. In this study, we tried to determine the causes of severe infection in patients with SSc and to reveal the factors associated with severe infection. Materials and methods: We retrospectively examined 214 SSc patients between January 2010 and August 2020. Forty-seven patients with at least one severe infection and 167 patients without severe infection were compared. Results: A total of 76 episodes of severe infections were detected in 47 (22%) patients. Common infections included pneumonia, infected digital ulcer, …
Effectiveness Of Virtual Reality-Based Vestibular Rehabilitation In Patients With Peripheral Vestibular Hypofunction, Yuşa Başoğlu, Mustafa Bülent Şerbetçi̇oğlu, İlayda Çeli̇k, Hasan Demi̇rhan
Effectiveness Of Virtual Reality-Based Vestibular Rehabilitation In Patients With Peripheral Vestibular Hypofunction, Yuşa Başoğlu, Mustafa Bülent Şerbetçi̇oğlu, İlayda Çeli̇k, Hasan Demi̇rhan
Turkish Journal of Medical Sciences
Background/aim: The rehabilitation of classical peripheral vestibular disorders is long and costly. Recently, interactive systems based on virtual reality (VR) technology have reduced the cost of vestibular rehabilitation therapy (VRT) and made the process more enjoyable. This study aims to investigate the effects of VR-based VRT in patients diagnosed with peripheral vestibular hypofunction (PVH). Materials and methods: In this study, a VR-based VRT program that utilized Sony Playstation®4 VR Head Mounted Display was applied to 25 patients (between 18-60) diagnosed with PVH. PVH was diagnosed by evaluating the patients' clinical histories, the findings in the "Micromedical Technologies VisualEyes Spectrum" videonystagmography …
An Evaluation Of The Results Of Convalescent Plasma Therapy Applied To Pregnant Womendiagnosed As Covid-19- Positive In A Pandemic Center: A Prospective Cohort Study, Seyi̇t Ahmet Erol, Atakan Tanaçan, Hakan Apaydin, Şule Göncü Ayhan, Deni̇z Oluklu, Derya Uyan Hendem, Serpi̇l Ünlü, Abdulsamet Erden, Özlem Moraloğlu Teki̇n, Ahmet Omma, İhsan Ateş, Orhan Küçükşahi̇n, Di̇lek Şahi̇n
An Evaluation Of The Results Of Convalescent Plasma Therapy Applied To Pregnant Womendiagnosed As Covid-19- Positive In A Pandemic Center: A Prospective Cohort Study, Seyi̇t Ahmet Erol, Atakan Tanaçan, Hakan Apaydin, Şule Göncü Ayhan, Deni̇z Oluklu, Derya Uyan Hendem, Serpi̇l Ünlü, Abdulsamet Erden, Özlem Moraloğlu Teki̇n, Ahmet Omma, İhsan Ateş, Orhan Küçükşahi̇n, Di̇lek Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: Convalescent plasma (CP) might be an additional treatment modality in COVID-19. The aim of this study was to compare CP-related clinical characteristics and perinatal outcomes in pregnant women with mild or moderate-severe COVID-19. Materials and methods: This prospective cohort study included 36 pregnant women (12 mild and 24 moderate-severe), who underwent CP therapy. The CP obtained from recently recovered donors was transfused to patients together with maximum supportive care and antiviral agents. The groups were then compared in respect of clinical characteristics, laboratory parameters, obstetric complications, and neonatal outcomes. Results: Significant differences were determined between the groups in respect …
The Effectiveness Of Anti-Interleukin-1 Therapy On Subclinical Inflammation Parametersduring The Attack-Free Period In Familial Mediterranean Fever Patients: A Case-Control Study, Ebru Atalar, İsmai̇l Doğan, Kevser Gök, Serdar Can Güven, Yüksel Maraş, Gülay Güleç Ceylan, Şükran Erten
The Effectiveness Of Anti-Interleukin-1 Therapy On Subclinical Inflammation Parametersduring The Attack-Free Period In Familial Mediterranean Fever Patients: A Case-Control Study, Ebru Atalar, İsmai̇l Doğan, Kevser Gök, Serdar Can Güven, Yüksel Maraş, Gülay Güleç Ceylan, Şükran Erten
Turkish Journal of Medical Sciences
Background/aim: Anti IL-1 therapy is useful in suppressing attacks in FMF patients with colchicine resistance, however, it is not certain whether subclinical inflammation can sufficiently be inhibited with anti-IL-1 therapy in FMF patients with amyloidosis. Materials and methods: Forty-six FMF patients receiving anti-interleukin-1 therapy and 36 healthy control patients were compared in terms of laboratory parameters. Also, FMF patients were further divided into two groups; those with amyloidosis and those without it, and these subgroups were compared to each other in terms of clinical and laboratory findings. Results: In comparison between the FMF and healthy control groups, erythrocyte sedimentation rate …
Pertussis Prevalence Among Adult Patients With Acute Cough, Ahmet İlbay, Mi̇ne Durusu Tanriöver, Işkin Pinar Zarakol, Ezgi̇ Çalişkan Güzelce, Hati̇ce Bölek, Serhat Ünal
Pertussis Prevalence Among Adult Patients With Acute Cough, Ahmet İlbay, Mi̇ne Durusu Tanriöver, Işkin Pinar Zarakol, Ezgi̇ Çalişkan Güzelce, Hati̇ce Bölek, Serhat Ünal
Turkish Journal of Medical Sciences
Background/aim: Bordetella pertussis infection remains an important health problem in adults due to the increasing prevalence in recent years. Pertussis in adults can be easily overlooked or misdiagnosed. We aimed to determine the prevalence of pertussis in adult patients with acute cough and the clinical features of the pertussis cases. Materials and methods: Internal Medicine and Pulmonology inpatient wards and outpatient clinics were screened between March 2017 and June 2018. Patients with cough duration between 1 week and 1 month were enrolled. Those who were on antibiotics for more than 5 days were excluded. A total of 115 patients were …
Assessment Of Subclinical Cardiovascular Alterations In Non-Functioning Adrenal Incidentalomas, Bülent Can, Peli̇n Karaca Özer, Büşra Can, Özge Telci̇ Çaklili
Assessment Of Subclinical Cardiovascular Alterations In Non-Functioning Adrenal Incidentalomas, Bülent Can, Peli̇n Karaca Özer, Büşra Can, Özge Telci̇ Çaklili
Turkish Journal of Medical Sciences
No abstract provided.
Application Of High-Flow Oxygen Therapy In Acute Pancreatitis Complicated With Acute Respiratory Dysfunction, Xiang Ji, Jie Zhou, Wenting Wu, Yan Tang, Tongrong Xu
Application Of High-Flow Oxygen Therapy In Acute Pancreatitis Complicated With Acute Respiratory Dysfunction, Xiang Ji, Jie Zhou, Wenting Wu, Yan Tang, Tongrong Xu
Turkish Journal of Medical Sciences
No abstract provided.
Radiomics Analysis Of Uterine Tumors In 18f-Flourodeoxyglucose Positron Emission Tomography For Prediction Of Lymph Node Metastases In Endometrial Carcinoma, Çi̇ğdem Soydal, Bulut Varli, Mi̇ne Araz, Batuhan Bakirarar, Sali̇h Taşkin, Uğur Firat Ortaç
Radiomics Analysis Of Uterine Tumors In 18f-Flourodeoxyglucose Positron Emission Tomography For Prediction Of Lymph Node Metastases In Endometrial Carcinoma, Çi̇ğdem Soydal, Bulut Varli, Mi̇ne Araz, Batuhan Bakirarar, Sali̇h Taşkin, Uğur Firat Ortaç
Turkish Journal of Medical Sciences
No abstract provided.
Determination Of Mirna Expression Profile In Patients With Prostate Cancer And Benign Prostate Hyperplasia, Okan Sancer, Pinar Aslan Koşar, Muhammet Yusuf Tepebaşi, Osman Ergün, Murat Demi̇r, Ali̇m Koşar
Determination Of Mirna Expression Profile In Patients With Prostate Cancer And Benign Prostate Hyperplasia, Okan Sancer, Pinar Aslan Koşar, Muhammet Yusuf Tepebaşi, Osman Ergün, Murat Demi̇r, Ali̇m Koşar
Turkish Journal of Medical Sciences
No abstract provided.
Conservative Management Of Patients With Endometrial Intraepithelial Neoplasia (Ein): Factors That Could Affect Response And Pregnancy Rates., Christos Iavazzo, Ioannis Gkegkes
Conservative Management Of Patients With Endometrial Intraepithelial Neoplasia (Ein): Factors That Could Affect Response And Pregnancy Rates., Christos Iavazzo, Ioannis Gkegkes
Turkish Journal of Medical Sciences
No abstract provided.
Investigation Of Cochlear Microphonics Recorded With Different Stimulus Types, Özgecan Güneşer, Ayşe Arzu Yi̇ği̇t, Asuman Alniaçik, Kürşat Yanarateş, Eda Çakmak
Investigation Of Cochlear Microphonics Recorded With Different Stimulus Types, Özgecan Güneşer, Ayşe Arzu Yi̇ği̇t, Asuman Alniaçik, Kürşat Yanarateş, Eda Çakmak
Turkish Journal of Medical Sciences
Background/aim: Electrocochleography (ECochG), one of the first defined tests under auditory evoked potentials, is a total electrical response of inner and outer hair cells inside the cochlea and auditory nerve record technique to the presence of an acoustic stimulus. T hese records can be used in Meniere disease and auditory neuropathy spectrum disorder diagnosis, intraoperative monitoring. In addition, the presence of cochlear microphonics plays a crucial role in auditory neuropathy spectrum disorder diagnosis. In our study, healthy individuals were tested with extratimpanic electrocochleography record method via Click and LS CE-Chirp stimulus, and the results were compared to the age, sex, …
Association Of Thiol/Disulphide Homeostasis With Bethesda Classification Of Thyroid Nodules And Thyroid Cancer, Muhammet Cüneyt Bi̇lgi̇ner, Abbas Ali̇ Tam, Sevgül Faki, Bağdagül Yüksel Güler, Özcan Erel, İbrahi̇m Kilinç, Di̇dem Özdemi̇r, Oya Topaloğlu, Reyhan Ersoy, Beki̇r Çakir
Association Of Thiol/Disulphide Homeostasis With Bethesda Classification Of Thyroid Nodules And Thyroid Cancer, Muhammet Cüneyt Bi̇lgi̇ner, Abbas Ali̇ Tam, Sevgül Faki, Bağdagül Yüksel Güler, Özcan Erel, İbrahi̇m Kilinç, Di̇dem Özdemi̇r, Oya Topaloğlu, Reyhan Ersoy, Beki̇r Çakir
Turkish Journal of Medical Sciences
Background/aim: Ultrasonography and fine-needle aspiration biopsy are frequently used to diagnose thyroid cancer. However, supportive data might be required in case of diagnostic difficulty. This study investigated whether there is a relationship between thiol/ disulphide homeostasis and cytological and histopathological diagnosis of thyroid nodules. Materials and methods: The patient group consisted of 81 individuals with euthyroid nodular (single/multiple) goiter scheduled for thyroidectomy, and the control group consisted of 28 age- and sex-matched healthy volunteers who had no thyroid nodule on ultrasonographic evaluation. All participants were selected among the admissions to the study clinic between June 2017 and June 2018, and …
Evaluation Of Subclinical Cardiovascular Disease By Carotid Intima Media Thickness, Epicardial Adipose Tissue Thickness, Serum Endocan, And Nesfatin-1 Levels In Patients With Primary Hyperparathyroidism, Muhammet Kocabaş, Yakup Alsancak, Mustafa Can, İlker Çordan, Hati̇ce Çalişkan Burgucu, Meli̇a Karaköse, Fatma Hümeyra Yerli̇kaya, Mustafa Kulaksizoğlu, Feri̇dun Karakurt
Evaluation Of Subclinical Cardiovascular Disease By Carotid Intima Media Thickness, Epicardial Adipose Tissue Thickness, Serum Endocan, And Nesfatin-1 Levels In Patients With Primary Hyperparathyroidism, Muhammet Kocabaş, Yakup Alsancak, Mustafa Can, İlker Çordan, Hati̇ce Çalişkan Burgucu, Meli̇a Karaköse, Fatma Hümeyra Yerli̇kaya, Mustafa Kulaksizoğlu, Feri̇dun Karakurt
Turkish Journal of Medical Sciences
Background/aim: Data on the presence and extent of cardiovascular disease (CVD) risk in primary hyperparathyroidism (PHPT) are conflicting. In our study, we aimed to investigate the increased CVD risk in patients with PHPT by carotid intima-media thickness (CIMT), epicardial adipose tissue (EAT) thickness, and serum levels of endocan and nesfatin-1. Materials and methods: Patients with PHPT (n = 44) and age- and sex-matched healthy control subjects (n = 40) were enrolled in this study. Demographic data of the participants were questioned. Serum endocan and nesfatin-1 concentrations were assessed using commercially available ELISA kits. Noninvasive measurements of CIMT and EAT thickness …
The Correlation Of Serum Spd-1 And Spd-L1 Levels With Clinical, Pathological Characteristics And Lymph Node Metastasis In Nonsmall Cell Lung Cancer Patients, Burcu Ancin, Mesut Meli̇h Özercan, Yi̇ği̇t Yilmaz, Serkan Uysal, Ulaş Kumbasar, Zeynep Saribaş, Erkan Di̇kmen, Riza Doğan, Meti̇n Demi̇rci̇n
The Correlation Of Serum Spd-1 And Spd-L1 Levels With Clinical, Pathological Characteristics And Lymph Node Metastasis In Nonsmall Cell Lung Cancer Patients, Burcu Ancin, Mesut Meli̇h Özercan, Yi̇ği̇t Yilmaz, Serkan Uysal, Ulaş Kumbasar, Zeynep Saribaş, Erkan Di̇kmen, Riza Doğan, Meti̇n Demi̇rci̇n
Turkish Journal of Medical Sciences
Background/aim: Significant advances have been achieved in immunotherapy for the treatment of lung cancer. It is known that tumor cells and cells in the tumor microenvironment express high amounts of programmed cell death ligand 1 (PD-L1). These PD-L1s interact with programmed cell death protein 1 (PD-1), causing immunosuppression. The aim of our study is to examine the correlation between the serum sPD-1 and sPD-L1 levels and clinicopathological characteristics in patients with nonsmall cell lung cancer. We also compared our results with the healthy population (control group). Materials and methods: Thirthy-seven nonsmall cell lung cancer (NSCLC) patients who were operated in …
Evaluation Of The Relationship Between Vitamin D Level And Adropin, Il-1ss, Il-6, And Oxidative Status In Women, Mehmet Zorlu, Abdüsselam Şekerci̇, Muhammed Tunç, Eray Meti̇n Güler, Bedi̇a Gülen, Cumali̇ Karatoprak, Muharrem Kiskaç, Mustafa Çakirca
Evaluation Of The Relationship Between Vitamin D Level And Adropin, Il-1ss, Il-6, And Oxidative Status In Women, Mehmet Zorlu, Abdüsselam Şekerci̇, Muhammed Tunç, Eray Meti̇n Güler, Bedi̇a Gülen, Cumali̇ Karatoprak, Muharrem Kiskaç, Mustafa Çakirca
Turkish Journal of Medical Sciences
Background/aim: Vitamin D, adropin, proinflammatory cytokines, and oxidative stress closely related with metabolic homeostasis and endothelial dysfunction. The aim of the present study is to investigate how vitamin D levels affect serum adropin, IL-1ß, IL-6, and oxidative stress. Materials and methods: A total of 77 female subjects were divided into 3 groups according to vitamin D levels. Biochemical parameters, adropin, IL-1ß, IL-6, oxidative stress markers were studied in these groups, and the results were compared statistically. Results: Serum adropin, IL-1ß, IL-6, total oxidant status (TOS) and total antioxidant status (TAS) and oxidative stress index (OSI) levels differed significantly between the …
Hand-Assisted Laparoscopic Donor Nephrectomy: 1864 Cases In 15 Years Of Experience, Bi̇lal Günaydin, Taha Uçar, Emre Arpali, Başak Akyollu, Serkan Akinci, Ci̇han Karataş, Kenan Öztorun, Burak Koçak
Hand-Assisted Laparoscopic Donor Nephrectomy: 1864 Cases In 15 Years Of Experience, Bi̇lal Günaydin, Taha Uçar, Emre Arpali, Başak Akyollu, Serkan Akinci, Ci̇han Karataş, Kenan Öztorun, Burak Koçak
Turkish Journal of Medical Sciences
Background/aim: To evaluate hand-assisted laparoscopic donor nephrectomy (HALDN) in terms of intraoperative and postoperative results. Materials and methods: After institutional review board approval was obtained, a total of 1864 HALDN operations performed between March 2007 and January 2022 were retrospectively analyzed. Age, sex, body mass index (BMI), status of smoking and presence of previous abdominal surgery, laterality, operative time, transfusion requirement, port counts, length of extraction incision, time until mobilization, time until oral intake, donor serum creatinine levels before and one week after the surgery, length of postoperative hospital stay, intraoperative complications, and postoperative recovery and complications were recorded and …
Magnetic Resonance Imaging Findings In Covid-19-Related Anosmia, Hüseyi̇n Çeti̇n, Ayşe Şule Ateş, Ogün Taydaş, Bahri̇ Elmas, Ertuğrul Güçlü
Magnetic Resonance Imaging Findings In Covid-19-Related Anosmia, Hüseyi̇n Çeti̇n, Ayşe Şule Ateş, Ogün Taydaş, Bahri̇ Elmas, Ertuğrul Güçlü
Turkish Journal of Medical Sciences
Background/aim: The coronavirus disease 2019 (COVID-19) mostly manifests with fever, shortness of breath, and cough, has also been found to cause some neurological symptoms, such as anosmia and ageusia. The aim of the study was to present the magnetic resonance imaging (MRI) findings of patients with anosmia-hyposmia symptoms and to discuss potential mechanisms in light of these findings. Materials and methods: Of the 2412 patients diagnosed with COVID-19-related pneumonia (RT-PCR at least once + clinically confirmed) between March and December 2020, 15 patients underwent olfactory MRI to investigate the cause of ongoing anosmia/ hyposmia symptoms were included in the study. …
The Use Of Fulvestrant Before Chemotherapy Improves Survival In Hormone-Positive Breast Cancer: A Real-Life Study, Deni̇z Can Güven, Hasan Çağri Yildirim, Enes Erul, Taha Koray Şahi̇n, İbrahi̇m Yahya Çakir, Oktay Hali̇t Aktepe, Neyran Kertmen, Ömer Di̇zdar, Sercan Aksoy
The Use Of Fulvestrant Before Chemotherapy Improves Survival In Hormone-Positive Breast Cancer: A Real-Life Study, Deni̇z Can Güven, Hasan Çağri Yildirim, Enes Erul, Taha Koray Şahi̇n, İbrahi̇m Yahya Çakir, Oktay Hali̇t Aktepe, Neyran Kertmen, Ömer Di̇zdar, Sercan Aksoy
Turkish Journal of Medical Sciences
Background/aim: We aimed to evaluate the efficacy of fulvestrant and its affecting clinical factors, including the optimal sequencing of fulvestrant and chemotherapy in a real-life cohort. Methods: The data of 256 metastatic hormone-positive breast cancer patients treated with fulvestrant were evaluated. The association of clinical factors with survival was analyzed with Kaplan-Meier and Cox-regression analyses. Results: The median age of patients was 57 years. More than half of the patients used fulvestrant in later lines and after chemotherapy (75.8%). The median progression-free (PFS) and overall survival (OS) of all cohort were 6.05 ± 0.56 and 29.70 ± 1.61 months, respectively. …
Is Microcystic, Elongated, And Fragmented Pattern Of Myometrial Invasion In Endometrioid Endometrial Carcinoma Associated With Survival?, Sultan Deni̇z Altindağ, Seyran Yi̇ği̇t, Serhat Şen
Is Microcystic, Elongated, And Fragmented Pattern Of Myometrial Invasion In Endometrioid Endometrial Carcinoma Associated With Survival?, Sultan Deni̇z Altindağ, Seyran Yi̇ği̇t, Serhat Şen
Turkish Journal of Medical Sciences
Background/aim: Microcystic, elongated, and fragmented (MELF) pattern is one of the myometrial invasion patterns in endometrioid endometrial carcinoma (EEC), and it has been associated with poor prognostic parameters, especially lymphovascular space invasion (LVSI) and lymph node metastasis (LNM). This study aims to represent the frequency of MELF pattern in EEC and the relationship between MELF pattern with clinicopathological parameters, overall survival (OS), and disease-free survival (DFS). Materials and methods: In this retrospective cohort study, we examined 233 patients with EEC diagnoses with the result of a total hysterectomy and bilateral salpingo-oophorectomy between 2009 and 2014. The association of MELF pattern …
The Lateralization Accuracy Of Inferior Petrosal Sinus Sampling In Cushing?S Disease: Experiences Of A Tertiary Center, Eli̇f Tutku Durmuş, Ayşegül Atmaca, Fati̇h Uzunkaya, Rami̇s Çolak, Buğra Durmuş
The Lateralization Accuracy Of Inferior Petrosal Sinus Sampling In Cushing?S Disease: Experiences Of A Tertiary Center, Eli̇f Tutku Durmuş, Ayşegül Atmaca, Fati̇h Uzunkaya, Rami̇s Çolak, Buğra Durmuş
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study is to determine the accuracy of bilateral inferior petrosal sinus sampling (IPSS) in lateralization and to investigate variables associated with accurate IPSS lateralization prediction. Materials and methods: Initially, data from 55 patients who underwent IPSS in our institution were reviewed retrospectively. IPSS lateralization and pituitary magnetic resonance imaging (MRI) results of these patients were compared with postoperative follow-up and immunohistochemical data to calculate the positive predictive values (PPVs) for IPSS and MRI. Variables likely to be associated with the accurate prediction of IPSS lateralization were analyzed. Results: Twenty-seven patients (85.2% female, mean age of …
Morphometric Examination Of Trigeminal Nerve And Its Adjacent Structures In Patients With Trigeminal Neuralgia: A Case-Control Study, Yunus Emre Kundakci, Nadi̇re Ünver Doğan, İnci̇ Kara, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Ahmet Kağan Karabulut
Morphometric Examination Of Trigeminal Nerve And Its Adjacent Structures In Patients With Trigeminal Neuralgia: A Case-Control Study, Yunus Emre Kundakci, Nadi̇re Ünver Doğan, İnci̇ Kara, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Ahmet Kağan Karabulut
Turkish Journal of Medical Sciences
Background/aim: Morphological differences that can lead the trigeminal nerve to neurovascular conflict and a new solitary pontine lesion are associated with the pathogenesis of trigeminal neuralgia (TN). In this case-control study, we aimed to contribute to the current discussions about the pathogenesis of TN by investigating the anatomical structures that may have an effect on the morphometric parameters of the trigeminal nerve. Materials and methods: This study included 25 patients with TN followed up for pain in the Department of Algology, Faculty of Medicine, and 25 age- and gender-matched controls. We performed morphometric measurements including the length and volume of …
Concordance Of Vestibular Test Batteries In Patients With Vestibular Neuritis, Burak Kabi̇ş, Hakan Tutar, Emre Gürses, Bülent Gündüz, Songül Aksoy
Concordance Of Vestibular Test Batteries In Patients With Vestibular Neuritis, Burak Kabi̇ş, Hakan Tutar, Emre Gürses, Bülent Gündüz, Songül Aksoy
Turkish Journal of Medical Sciences
Background/aim: A growing number of vestibular function tests are utilized to differentiate and verify the diagnosis of vestibular neuritis. The aim of this study is to retrospectively investigate the consistency of the results of the objective vestibular test batteries in patients with a preliminary diagnosis of vestibular neuritis. Materials and methods: We reviewed a total of 37 adult patients (mean age: 39.03 ± 11.67, 19 females, 18 males) who met the inclusion criteria with a prediagnosis of vestibular neuritis from 379 patients suffering vestibular symptoms. Caloric test (CVT), video head impulse test (vHIT), and ocular and cervical VEMP tests were …
Copy Number Variations In Patients With Idiopathic Recurrent Pregnancy Loss: An Arraycgh Approach, Onur Yildiz, Fatma Silan, Taner Karakaya, Öztürk Özdemi̇r
Copy Number Variations In Patients With Idiopathic Recurrent Pregnancy Loss: An Arraycgh Approach, Onur Yildiz, Fatma Silan, Taner Karakaya, Öztürk Özdemi̇r
Turkish Journal of Medical Sciences
Background/aim: It is not always possible to determine the causative basis of pregnancy losses and even today it has been reported that 50% of cases with recurrent pregnancy loss (RPL) have no reason to be detected. In our study, it is aimed to reveal the copy number variations (CNVs) of the genes which presumably have a potential effect in individuals with RPL and contribute to subsequent functional studies in the follow-up. Materials and methods: We retrospectively evaluated the array-comparative genomic hybridization (aCGH) data of cytogenetically 64 normal individuals (21 couples, 11 unrelated women, and 11 unrelated men) who had applied …
Evaluation Of Metabolic Changes In Fdg Pet/Ct Imaging After Mrna-Based Covid-19 Vaccination, Serkan İşgören, Gi̇zem Köroğlu, Gözde Dağliöz Görür, Hakan Demi̇r
Evaluation Of Metabolic Changes In Fdg Pet/Ct Imaging After Mrna-Based Covid-19 Vaccination, Serkan İşgören, Gi̇zem Köroğlu, Gözde Dağliöz Görür, Hakan Demi̇r
Turkish Journal of Medical Sciences
Background/aim: It isimportant to evaluate the vaccine-related metabolic changes on FDG PET/CT to avoid confusing results. We here aimed to assess the frequency and intensity of regional and systemic metabolic PET/CT changes of patients who received the mRNAbased COVID-19 vaccine (BNT162b2-Pfizer/BioNTech) and to analyze possible factors affecting these changes. Materials and methods: Among the patients who underwent FDG PET/CT for any indication in our department between July 2021 and December 2021, 129 volunteer patients with a history of COVID-19 vaccination were included in this prospective observational study. Bilateral axillary lymph nodes, ipsilateral deltoid muscle, bone marrow, spleen, thyroid, and liver …
Enhancing Effect Of Nicotine On Electrical Field Stimulation Elicited Contractile Responses In Isolated Rabbit Bladder Straight Muscle; The Role Of Cannabinoid And Vanilloid Receptors, Sevi̇l Özger İlhan, Gökçe Sevi̇m Öztürk Fi̇ncan, Yağmur Okçay, Derya Sebi̇le Koç, Celi̇l İlker Aşkin, Ayşe Kübra Ki̇bar, İsmai̇l Mert Vural, Yusuf Sarioğlu
Enhancing Effect Of Nicotine On Electrical Field Stimulation Elicited Contractile Responses In Isolated Rabbit Bladder Straight Muscle; The Role Of Cannabinoid And Vanilloid Receptors, Sevi̇l Özger İlhan, Gökçe Sevi̇m Öztürk Fi̇ncan, Yağmur Okçay, Derya Sebi̇le Koç, Celi̇l İlker Aşkin, Ayşe Kübra Ki̇bar, İsmai̇l Mert Vural, Yusuf Sarioğlu
Turkish Journal of Medical Sciences
Background/aim: Nicotine acts as an agonist of nicotinic acetylcholine receptors (nAChR). These receptors belong to a superfamily of ligand-gated ion channels. We previously demonstrated that nicotine increased electrical field stimulation (EFS)-induced contractile or relaxation responses, possibly by facilitating neurotransmitter release from nerve terminals in various rabbit tissues. Studies have shown that there is an interaction between the endocannabinoid and nicotinic systems. This study aimed to investigate the interaction between nicotine and the endocannabinoid system in the rabbit urine bladder and also investigate the enhancing effect of nicotine on EFS-induced contractile responses in rabbit isolated bladder smooth muscle and its interaction …
Management Of Recurrent Hemoptysis: A Single-Center Experience, Seda Tural Önür, Sedat Altin, Fatma Tokgöz Akyil, Kaan Kara, Si̇nem Nedi̇me Sökücü, Cengi̇z Özdemi̇r, Mehmet Aki̇f Özgül, Muzaffer Meti̇n, Levent Cansever, Aysun Ölçmen, Nuri̇ Özgür Kiliçkesmez
Management Of Recurrent Hemoptysis: A Single-Center Experience, Seda Tural Önür, Sedat Altin, Fatma Tokgöz Akyil, Kaan Kara, Si̇nem Nedi̇me Sökücü, Cengi̇z Özdemi̇r, Mehmet Aki̇f Özgül, Muzaffer Meti̇n, Levent Cansever, Aysun Ölçmen, Nuri̇ Özgür Kiliçkesmez
Turkish Journal of Medical Sciences
Background/aim: A successful planning methodology for patients with hemoptysis promises overall improvement in patient care. Conducted in a reference center for chest diseases, the present study aims to analyze characteristics and predictors of interventional methods in patients with recurrent hemoptysis. Materials and methods: The present study is a single-center, retrospective observational study. Between 2015 and 2018, 5973 patients with follow-up data until 2021 requiring more than one hospitalization due to recurrent hemoptysis were investigated. Patient characteristics, the amount of hemoptysis, baseline admission parameters, interventional procedures of bronchial artery embolization (BAE), fiberoptic bronchoscopy, rigid bronchoscopy, and surgical resections applied were analyzed …
Extremely High Erythrocyte Sedimentation Rate Revisited In Rheumatic Diseases: A Singlecenter Experience, Zehra Özsoy, Emre Bi̇lgi̇n, Melek Seren Aksun, İmdat Eroğlu, Umut Kalyoncu
Extremely High Erythrocyte Sedimentation Rate Revisited In Rheumatic Diseases: A Singlecenter Experience, Zehra Özsoy, Emre Bi̇lgi̇n, Melek Seren Aksun, İmdat Eroğlu, Umut Kalyoncu
Turkish Journal of Medical Sciences
Background/aim: The objectives were to define the distribution of rheumatic diseases in patients with erythrocyte sedimentation rate (ESR) ≥ 100 mm/h and to find variables that can differentiate main study groups from others. Materials and methods: Charts of patients admitted with ESR ≥ 100 mm/h between 2015 and 2020 were reviewed. Patients were divided into four diagnostic groups based on etiology: infection (without a rheumatic diagnosis), oncologic (without a rheumatic diagnosis), rheumatic, and no definitive diagnosis. Patients with the rheumatic diagnosis were divided into three main study groups: those who had been recently diagnosed with a rheumatic disease, those who …
Factors Affecting Patient-Acceptable Symptom States And Treatment Decision In Familial Mediterranean Fever, Derya Yildirim, İbrahi̇m Vasi̇, Erdi̇ Tahta, Riza Can Kardaş, Burcugül Özkiziltaş, Hami̇t Küçük, Mehmet Aki̇f Öztürk, Şemi̇nur Haznedaroğlu, Berna Göker, Abdurrahman Tufan
Factors Affecting Patient-Acceptable Symptom States And Treatment Decision In Familial Mediterranean Fever, Derya Yildirim, İbrahi̇m Vasi̇, Erdi̇ Tahta, Riza Can Kardaş, Burcugül Özkiziltaş, Hami̇t Küçük, Mehmet Aki̇f Öztürk, Şemi̇nur Haznedaroğlu, Berna Göker, Abdurrahman Tufan
Turkish Journal of Medical Sciences
Background/aim: Familial Mediterranean fever [FMF] is the most common autoinflammatory disease characterized by inflammatory attacks of fever and polyserositis. Patients' quality of life is significantly affected due to recurrent excruciating pain attacks and complications. This study is performed to evaluate the parameters most affecting patients' satisfaction from treatment. Materials and methods: Three hundred and forty-six consecutive patients diagnosed with FMF were enrolled in this study. Current treatment, acute phase proteins, number, type, and severity of predominant attacks, absenteeism from work/school in the last three months were recorded, and the participants were asked whether they needed additional treatment to evaluate Patient …
A Device That Facilitates Screwing At An Appropriate Angle In Quadrilateral Surface Fractures: 105-Degree Drill Attachment, Emre Gültaç, Cem Yalin Kilinç, Fati̇h İlker Can, İsmai̇l Gökhan Şahi̇n, Ahmet Emrah Açan, Çağatay Gemci̇, Nevres Hürri̇yet Aydoğan
A Device That Facilitates Screwing At An Appropriate Angle In Quadrilateral Surface Fractures: 105-Degree Drill Attachment, Emre Gültaç, Cem Yalin Kilinç, Fati̇h İlker Can, İsmai̇l Gökhan Şahi̇n, Ahmet Emrah Açan, Çağatay Gemci̇, Nevres Hürri̇yet Aydoğan
Turkish Journal of Medical Sciences
No abstract provided.
Morbid Obesity Leads To Increased Skin Autofluorescence Independent Of Metabolic Syndrome Components, Tuğçe Apaydin, Di̇lek Yavuz
Morbid Obesity Leads To Increased Skin Autofluorescence Independent Of Metabolic Syndrome Components, Tuğçe Apaydin, Di̇lek Yavuz
Turkish Journal of Medical Sciences
Background/aim: Obesity, diabetes mellitus, and metabolic syndrome (MetS) are associated with increased accumulated skin advanced glycation end products. We aimed to evaluate the association of MetS components with skin autofluorescence (SAF) in patients with morbid obesity. Material and methods: Eight hundred and one patients with morbid obesity and 94 age-matched controls with normal body mass index (BMI) and normal glucose metabolism were included. Advanced glycation end products (AGEs) were measured using SAF in the forearm, with an AGE reader. Results: The prevalence of MetS in patients with morbid obesity was 65.5% (n = 525). Type 2 diabetes mellitus (type 2 …