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Folate And Homocysteine Metabolisms And Their Roles In The Biochemical Basis Of Neuropsychiatry, Alpaslan Coşar, Osman Meti̇n İpci̇oğlu, Ömer Özcan, Mustafa Gültepe Jan 2014

Folate And Homocysteine Metabolisms And Their Roles In The Biochemical Basis Of Neuropsychiatry, Alpaslan Coşar, Osman Meti̇n İpci̇oğlu, Ömer Özcan, Mustafa Gültepe

Turkish Journal of Medical Sciences

The term 'one-carbon metabolism' is commonly used to describe 3 separate metabolic processes: folate metabolism, the homocysteine remethylation cycle, and the transsulfuration pathway. Folate metabolism concerns the biochemical reactions in which endogenous and exogenous one-carbon units are transferred to tetrahydrofolates. The remethylation cycle is used for the synthesis of methionine from homocysteine with one-carbon units that come from folate. This methionine is then used for the synthesis of S-adenosyl methionine, which is a general donor of methyl groups for many biochemical reactions in the human body. In the transsulfuration pathway, some amino acids and polypeptides, such as cystathionine, cysteine, and …


The Obesity Prevalence Of The Students Between The Ages Of 5-19 In Kütahya, Mehmet Kaya, Ayli̇n Sayan, Mustafa Bi̇ri̇nci̇, Mevlüt Yildiz, Kami̇l Türkmen Jan 2014

The Obesity Prevalence Of The Students Between The Ages Of 5-19 In Kütahya, Mehmet Kaya, Ayli̇n Sayan, Mustafa Bi̇ri̇nci̇, Mevlüt Yildiz, Kami̇l Türkmen

Turkish Journal of Medical Sciences

To determine the prevalence of obesity among students between the ages of 5 and 19 in Kütahya, and to determine the factors associated with obesity prevalence. Materials and methods: The population in the survey was formed of students between the ages of 5 and 19 in the schools of Kütahya. Within the scope of this survey, obesity was evaluated in accordance with the percentile values indicated in a study on the body weight and height, head circumference, and body mass index reference values of Turkish children that was published in 2008. Results: It was determined that 6.5% of the students …


Serum Amyloid A, Fetuin-A, And Pentraxin-3 Levels In Patients With Ischemic Stroke: Novel Prognostic Biomarkers?, Sevi̇lay Sezer, Fatma Uçar, Ersi̇n Kasim Ulusoy, Serpi̇l Erdoğan, Şule Bi̇len, Cevdet Züngün, Sema Uysal, Haci Kemal Erdemli̇ Jan 2014

Serum Amyloid A, Fetuin-A, And Pentraxin-3 Levels In Patients With Ischemic Stroke: Novel Prognostic Biomarkers?, Sevi̇lay Sezer, Fatma Uçar, Ersi̇n Kasim Ulusoy, Serpi̇l Erdoğan, Şule Bi̇len, Cevdet Züngün, Sema Uysal, Haci Kemal Erdemli̇

Turkish Journal of Medical Sciences

Inflammation plays an important role in acute ischemic stroke. In this study we aimed to investigate the relationship between acute ischemic stroke and serum amyloid A, fetuin-A, and pentraxin-3 which are inflammation markers. Materials and methods: We enrolled 52 patients with acute ischemic stroke and 30 sex-matched control subjects in the study. The patients were followed for 3 months. We evaluated the common risk factors, laboratory variables, and neurological examination of stroke patients according to prognosis scales. Results: The median serum amyloid A, fetuin-A, and pentraxin-3 levels in the stroke patients were higher than in control subjects (respectively, P = …


Attachment Style And Perceived Social Support As Predictors Of Biopsychosocial Adjustment To Cancer, Ayşe Gül Yilmaz Özpolat, Tuğba Ayaz, Özlem Konağ, Asi̇ye Özkan Jan 2014

Attachment Style And Perceived Social Support As Predictors Of Biopsychosocial Adjustment To Cancer, Ayşe Gül Yilmaz Özpolat, Tuğba Ayaz, Özlem Konağ, Asi̇ye Özkan

Turkish Journal of Medical Sciences

Social support is associated with a decrease in psychological symptoms and a better quality of life in cancer patients. The aim of this study was to investigate the role of attachment dimensions on social and psychological adjustment to cancer and to explore the social and psychological adjustments, and medical adherence, among patients. Materials and methods: The study was conducted with 68 cancer patients, between 18 and 74 years of age. The measures taken were the Demographic Information Form, Multidimensional Scale of Perceived Social Support (MSPSS), Experiences in Close Relationships-Revised (ECR-R), and Psychosocial Adjustment to Illness Scale (PAIS-SR). Results: The results …


Distal Radius Measurements And Efficacy Of Fixed-Angle Locking Volar Plates, İsmai̇l Ağir, Mahmut Nedi̇m Ayteki̇n, Fati̇h Küçükdurmaz, Onur Başci, Ci̇hangi̇r Teti̇k Jan 2014

Distal Radius Measurements And Efficacy Of Fixed-Angle Locking Volar Plates, İsmai̇l Ağir, Mahmut Nedi̇m Ayteki̇n, Fati̇h Küçükdurmaz, Onur Başci, Ci̇hangi̇r Teti̇k

Turkish Journal of Medical Sciences

For surgical treatment of unstable distal radius fractures, fixed-angled locking volar plate fixation is becoming popular nowadays because of some advantages over other surgical techniques. In this article, we discuss the fitting of fixed-angle locking volar plates to the distal radius in relation to the changes in the distal radial angles. Materials and methods: First, we took conventional radiography images of 18 dried radii and later we measured the palmar subchondral angle, dorsal subchondral angle, mid-subchondral angle, and palmar cortical angle using lateral radiography. Results: According to the measurements, the volar subchondral angles (alpha) ranged from 10.2° to 28.1°, the …


What Is The Best Radiological Method To Predict The Actual Weight Of The Prostate?, Meti̇n Kiliç, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ali̇ Fuat Atmaca, Abdullah Erdem Canda, Mevlana Derya Balbay Jan 2014

What Is The Best Radiological Method To Predict The Actual Weight Of The Prostate?, Meti̇n Kiliç, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ali̇ Fuat Atmaca, Abdullah Erdem Canda, Mevlana Derya Balbay

Turkish Journal of Medical Sciences

We compared the weight of the prostate specimen extracted after radical prostatectomy with preoperatively estimated weights of the prostate by different imaging techniques. Materials and methods: Prostate weights were estimated by transabdominal ultrasonography (TAUS), transrectal ultrasonography (TRUS), and computed tomography (CT) preoperatively before radical prostatectomy. Prostatectomy specimens were weighed postoperatively and the actual prostate weights were calculated. Statistical analyses were done using 95% confidence intervals with repeated measurement analysis of variance and intraclass correlation coefficients. Results: Of the 163 patients enrolled in the study, the mean age was 64.2 ± 6.4 (range: 45 to 76) years. The mean postoperative prostate …


Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r Jan 2014

Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r

Turkish Journal of Medical Sciences

To analyze the phenolic composition of the Cimin grape, which is 1 of 2 grape varieties with a protected geographical indication in Turkey and is used locally to treat the symptoms of some disorders such as impotence and cardiovascular diseases, and to investigate its antioxidant potency against oxidant mediators in the models of intra- and extracellular surroundings. Materials and methods: Cimin grape samples were classified into 5 groups according to the grape's tissues and the extraction solvents used. Free radical scavenging (DPPH) and antilipid peroxidation product [thiobarbituric acid reactive substance (TBARS) and conjugated diene (CD)] levels of the grape tissues …


Prognostic Value Of Neutrophil/Lymphocyte Ratio In Patients With Pulmonary Embolism, Umut Yücel Çavuş, Si̇nan Yildirim, Ertan Sönmez, Çağatay Ertan, Özcan Özeke Jan 2014

Prognostic Value Of Neutrophil/Lymphocyte Ratio In Patients With Pulmonary Embolism, Umut Yücel Çavuş, Si̇nan Yildirim, Ertan Sönmez, Çağatay Ertan, Özcan Özeke

Turkish Journal of Medical Sciences

Preliminary evidence suggests that inflammation plays a role in the development and prognosis of pulmonary embolism (PE). We used the neutrophil/lymphocyte ratio (NLR) as a measure of systemic inflammation and investigated its association with PE. Materials and methods: A total of 266 patients who were diagnosed with PE and a control group of 124 age- and sex-matched healthy subjects were included in this study. We further classified the PE patients into 2 groups: those who survived and those who died in the first 30 days. Baseline NLR was measured by dividing neutrophil count to lymphocyte count and was compared between …


Choroidal Thickness In Healthy Turkish Subjects, Erol Coşkun, Seydi̇ Okumuş, Bülent Gürler, Ramazan Yayuspayi, Burak Ören, Erdal Kaydu, Ayşegül Çömez, İbrahi̇m Erbağci Jan 2014

Choroidal Thickness In Healthy Turkish Subjects, Erol Coşkun, Seydi̇ Okumuş, Bülent Gürler, Ramazan Yayuspayi, Burak Ören, Erdal Kaydu, Ayşegül Çömez, İbrahi̇m Erbağci

Turkish Journal of Medical Sciences

To investigate choroidal thickness in healthy Turkish subjects. Materials and methods: Refraction, axial length (AXL) measurement, anterior chamber, and fundus examinations were performed. Eyes that had any retinal or choroidal pathology were excluded from the study. Enhanced-depth imaging optical coherence tomography was used to evaluate choroidal thickness. Results: 139 eyes from 70 subjects were investigated. The mean age, AXL, spherical equivalent refractive error (SE), and subfoveal choroidal thickness (SCT) were 34.7 ± 12.7 years, 23.31 ± 0.91 mm, -0.15 ± 1.64 diopters (D), and 326 ± 60 µm, respectively. A negative correlation was found between SCT and AXL (P = …


The Diagnostic Value Of Ischemia-Modified Albumin In The Diagnosis Of Aortic Pathology, Oğuz Eroğlu, Süha Türkmen, Ahmet Menteşe, Gökalp Altun, Süleyman Türedi̇, Umut Eryi̇ği̇t, Süleyman Caner Karahan, Abdülkadi̇r Gündüz Jan 2014

The Diagnostic Value Of Ischemia-Modified Albumin In The Diagnosis Of Aortic Pathology, Oğuz Eroğlu, Süha Türkmen, Ahmet Menteşe, Gökalp Altun, Süleyman Türedi̇, Umut Eryi̇ği̇t, Süleyman Caner Karahan, Abdülkadi̇r Gündüz

Turkish Journal of Medical Sciences

To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm. Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with similar demographic characteristics. Results: Mean IMA values were 0.89 ± 0.21 absorbance units (ABSU) in the aortic aneurysm group (P < 0.001), 0.70 ± 0.12 ABSU in the aortic dissection group (P < 0.001), 0.98 ± 0.23 ABSU in the aneurysm and dissection group (P < 0.001), 0.84 ± 0.16 ABSU in the aneurysm and rupture group (P < 0.001), and 0.87 ± 0.27 ABSU in the aneurysm, dissection, and rupture group (P < 0.001). Mean IMA value for the subjects in the control group was 0.62 ± 0.17 ABSU. All the differences between the aortic pathology groups' IMA values and those of the control group were statistically significant (P < 0.001). Conclusion: On the basis of the findings from this study, serum IMA levels are higher in patients with aortic pathology compared to healthy individuals. This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.


Comparison Of The Effects Of Different Percutaneous Tracheotomy Techniques On Acute Tracheal Trauma, Cengi̇z Beki̇r Demi̇rel, Hacer Haltaş, Hasan Kutluk Pampal, Yusuf Ünal, Berri̇n Işik, Mükerrem Uysal Jan 2014

Comparison Of The Effects Of Different Percutaneous Tracheotomy Techniques On Acute Tracheal Trauma, Cengi̇z Beki̇r Demi̇rel, Hacer Haltaş, Hasan Kutluk Pampal, Yusuf Ünal, Berri̇n Işik, Mükerrem Uysal

Turkish Journal of Medical Sciences

As it can easily be performed at the bedside with minimal morbidity, percutaneous dilatational tracheotomy (PDT) is preferred over surgical tracheotomy. The aim of this study is to compare the effects of different PDT techniques on posterior tracheal wall injury. Materials and methods: The study was conducted at the Gazi University Laparoscopy Training Center after approval was granted by the ethics committee. After sedation with xylazine/ketamine, electrocardiography, peripheral oxygen saturation, and blood pressure were monitored. Propofol was used to achieve the desired level of sedation during the procedure. There were 16 pigs, randomly allocated into 4 groups. Multiple, single, forceps, …


Increasing Resistance Of Nosocomial Acinetobacter Baumannii: Are We Going To Be Defeated?, Tümer Güven, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, Ayşe Kaya Kalem, Fatma Eser, Mehmet Akin Taşyaran Jan 2014

Increasing Resistance Of Nosocomial Acinetobacter Baumannii: Are We Going To Be Defeated?, Tümer Güven, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, Ayşe Kaya Kalem, Fatma Eser, Mehmet Akin Taşyaran

Turkish Journal of Medical Sciences

To investigate the change of the antibiotic resistance profiles of the nosocomial Acinetobacter baumannii isolates in intensive care units (ICUs) between the years 2008 and 2011. Materials and methods: A. baumannii isolates that were responsible for ICU-acquired nosocomial infections between 2008 and 2011 were included in the study. The susceptibility rates of the antibiotics that are mainly used in the treatment of Acinetobacter infections were compared by years. Clinical and Laboratory Standards Institute criteria were used to determine antimicrobial susceptibility. Results: There were 252 infection episodes detected in 229 hospitalized patients in the ICU that were caused by A. baumannii. …


Single Port Thoracoscopic Sympathectomy For Primary Palmar Hyperhidrosis In Adolescence, Nesi̇mi̇ Günal, Berkant Özpolat, Yasemi̇n Dere Günal, Koray Dural Jan 2014

Single Port Thoracoscopic Sympathectomy For Primary Palmar Hyperhidrosis In Adolescence, Nesi̇mi̇ Günal, Berkant Özpolat, Yasemi̇n Dere Günal, Koray Dural

Turkish Journal of Medical Sciences

Hyperhidrosis is defined as excessive sweating beyond the physiologic needs of a person. Palmar hyperhidrosis in the adolescent period may have an impact on school work and may cause psychological problems. In this study we aim to increase awareness of this disregarded problem. Materials and methods: We explicated the early outcomes of 7 consecutive adolescents, where single port video-assisted thoracoscopic sympathectomy was performed for primary palmar hyperhidrosis. Patients were evaluated for symptom resolution, which was defined as complete dryness, patient satisfaction, operative complications, and compensatory sweating. Results: In total 13 thoracoscopic procedures were done in 7 adolescents, consisting of 4 …


Incidental Parathyroidectomy During Thyroid Surgery: Risk Factors, Incidence, And Outcomes, Bünyami̇ Özoğul, Müfi̇de Nuran Akçay, Abdullah Kisaoğlu, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk, Bülent Aydinli Jan 2014

Incidental Parathyroidectomy During Thyroid Surgery: Risk Factors, Incidence, And Outcomes, Bünyami̇ Özoğul, Müfi̇de Nuran Akçay, Abdullah Kisaoğlu, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk, Bülent Aydinli

Turkish Journal of Medical Sciences

Incidental removal of the parathyroid glands is common in some cases. In this trial, we investigated the risk factors, incidence, and outcomes associated with incidental excision of the parathyroid glands during thyroid surgery. Materials and methods: The records of patients who had undergone thyroid surgery in our department between January 2006 and December 2011 were retrospectively evaluated. Results: A total of 801 patients were enrolled in the trial. The number of incidental parathyroidectomies was determined as 19 (2.3%). Statistical evaluation revealed that sex (P > 0.05) and type of surgical operation (P > 0.05) were not associated with a significant impact on …


Puva Phototherapy-Induced Secondary Amyloidosis In Patients With Mycosis Fungoides: A Rare Adverse Effect Of Phototherapy, Itir Ebru Zemheri̇, Sidika Şeyma Özkanli, İlki̇n Zi̇ndanci, Serkan Şenol, Özge Akbulak, Fi̇li̇z Topaloğlu Demi̇r Jan 2014

Puva Phototherapy-Induced Secondary Amyloidosis In Patients With Mycosis Fungoides: A Rare Adverse Effect Of Phototherapy, Itir Ebru Zemheri̇, Sidika Şeyma Özkanli, İlki̇n Zi̇ndanci, Serkan Şenol, Özge Akbulak, Fi̇li̇z Topaloğlu Demi̇r

Turkish Journal of Medical Sciences

Amyloidosis is a common disorder in adults. Secondary amyloidosis in patients with mycosis fungoides (MF) after photochemotherapy with 8-methoxypsoralen followed by ultraviolet A (PUVA) treatment has not been reported. Our aim is to describe the clinical and histological features of PUVA phototherapy-induced secondary amyloidosis. Materials and methods: Sixty-one patients with MF treated with PUVA phototherapy were analyzed clinically and pathologically and by staining with Congo red and crystal violet. Results: Of 61 patients, 5 met the study criteria. Secondary amyloidosis was detected in 5 patients treated with PUVA. The secondary amyloidosis appeared after a mean of 56 exposures (range: 30-81) …


Is Perioperative Examination Of Frozen Sections Necessary In Nephron-Sparing Surgery?, Mehmet Kalkan, Soner Yalçinkaya, Coşkun Şahi̇n, Yeşi̇m Üçkurt, Ömer Etli̇k Jan 2014

Is Perioperative Examination Of Frozen Sections Necessary In Nephron-Sparing Surgery?, Mehmet Kalkan, Soner Yalçinkaya, Coşkun Şahi̇n, Yeşi̇m Üçkurt, Ömer Etli̇k

Turkish Journal of Medical Sciences

To evaluate the role of perioperative freezing in the management of surgical procedures in patients with malignant renal masses. Materials and methods: The study group consisted of 17 patients diagnosed with renal masses who underwent nephron-sparing surgery. The group included 5 females and 12 males aged from 44 to 68 years (mean = 54.6). The mean mass size was 5.5 cm. Mass locations were as follows: 9 were in the lower pole, 4 were in the mid-pole, and 6 were in the upper pole. Perioperative freezing was not carried out. The patients were followed-up in a period ranging from 3 …


Acute Q Fever Among Febrile Patients In Zahedan, Southeastern Iran, Maliheh Metanat, Nahid Sepehri Rad, Roya Alavi-Naini, Shahram Shahreki, Batool Sharifi-Mood, Aida Akhavan, Zahra Poormotaseri Jan 2014

Acute Q Fever Among Febrile Patients In Zahedan, Southeastern Iran, Maliheh Metanat, Nahid Sepehri Rad, Roya Alavi-Naini, Shahram Shahreki, Batool Sharifi-Mood, Aida Akhavan, Zahra Poormotaseri

Turkish Journal of Medical Sciences

So far, few studies have been conducted on Q fever in Iran. The objective of this study was to determine the frequency of acute Q fever in febrile patients admitted to Boo-Ali Hospital in Zahedan (southeastern Iran). Materials and methods: In this study, 105 febrile patients suspected of having brucellosis were examined using indirect immunofluorescent assay kit for the detection of Coxiella burnetii IgM and IgG phase antibodies in their serum. Serum with a phase II IgG titer of =>256 and a phase II IgM titer of =>50 was predictive for acute Q fever. Additionally, a 4-fold rise …


Factors Associated With The Pain Catastrophizing Scale And Validation In A Sample Of The Turkish Population, Mustafa Süren, İsmai̇l Okan, Azi̇z Mehmet Gökbakan, Zi̇ya Kaya, Ünal Erkorkmaz, Semi̇h Arici, Serkan Karaman, Mürsel Kahveci̇ Jan 2014

Factors Associated With The Pain Catastrophizing Scale And Validation In A Sample Of The Turkish Population, Mustafa Süren, İsmai̇l Okan, Azi̇z Mehmet Gökbakan, Zi̇ya Kaya, Ünal Erkorkmaz, Semi̇h Arici, Serkan Karaman, Mürsel Kahveci̇

Turkish Journal of Medical Sciences

The aim of this study was to validate the Pain Catastrophizing Scale (PCS) in the Turkish population and to investigate its correlation with the demographic and clinical characteristics of patients. Materials and methods: Volunteer patients, who were scheduled for elective surgery and who applied to the Outpatient Clinic of Anesthesiology for preoperative evaluation, were asked to complete a PCS form. The patient's age, sex, educational level, marital status, presence of chronic pain, and American Society of Anesthesiologists score were recorded, and PCS scores and demographic variables were compared statistically. Results: Of the 257 patients enrolled in the study, 136 were …


Bone Mineral Density And Vitamin D Status In Children And Adolescents With Congenital Adrenal Hyperplasia, Fatma Demi̇rel, Özlem Kara, Derya Tepe, İhsan Esen Jan 2014

Bone Mineral Density And Vitamin D Status In Children And Adolescents With Congenital Adrenal Hyperplasia, Fatma Demi̇rel, Özlem Kara, Derya Tepe, İhsan Esen

Turkish Journal of Medical Sciences

To determine the prevalence of and risk factors for decreased bone mineral density (BMD) and vitamin D deficiency in children and adolescents with congenital adrenal hyperplasia (CAH). Materials and methods: This study was conducted on 30 girls and 22 boys with CAH (age range = 5-20 years) with median age of 12.0 years. BMD values of lumbar vertebras (L1-L4), which were determined by dual-energy X-ray absorptiometry, were used to calculate z-scores according to chronological age. A serum 25-hydroxyvitamin D level of


Protective Role Of Caffeic Acid Phenethyl Ester On Serum Cholinesterase Inhibition By Acute Exposure To Diazinon In Rats, Esi̇n Oğuzhanoğlu, Ahmet Cenk Andaç, Adnan Tüfek, Lütfi̇ Yavuz, Hüseyi̇n Vural, Osman Gökalp Jan 2014

Protective Role Of Caffeic Acid Phenethyl Ester On Serum Cholinesterase Inhibition By Acute Exposure To Diazinon In Rats, Esi̇n Oğuzhanoğlu, Ahmet Cenk Andaç, Adnan Tüfek, Lütfi̇ Yavuz, Hüseyi̇n Vural, Osman Gökalp

Turkish Journal of Medical Sciences

To evaluate whether caffeic acid phenethyl ester (CAPE), a flavonoid-like natural compound plentifully found in beeswax, has a protective effect on diazinon-induced serum cholinesterase (ChE) inhibition in rats. Materials and methods: Animals were divided into 4 groups. The first animal group was not treated with any substance. The second animal group was orally given a 200 mg/kg body weight (bw) sublethal dose of diazinon. The third animal group was injected intraperitoneally with 2.84 mg (10 µmol)/kg bw of CAPE 1 day prior to administration of 200 mg/kg bw of diazinon orally. The fourth animal group was intraperitoneally injected with 2.84 …


Liver Enzymes, Mean Platelet Volume, And Red Cell Distribution Width In Gestational Diabetes, Serpi̇l Erdoğan, Özhan Özdemi̇r, Halef Okan Doğan, Sevi̇lay Sezer, Cemal Reşat Atalay, Fatma Meri̇ç Yilmaz, Yüksel Koca Jan 2014

Liver Enzymes, Mean Platelet Volume, And Red Cell Distribution Width In Gestational Diabetes, Serpi̇l Erdoğan, Özhan Özdemi̇r, Halef Okan Doğan, Sevi̇lay Sezer, Cemal Reşat Atalay, Fatma Meri̇ç Yilmaz, Yüksel Koca

Turkish Journal of Medical Sciences

To investigate the value of measuring liver enzymes, red cell distribution width (RDW), and mean platelet volume (MPV) in predicting the development of gestational diabetes mellitus (GDM). Materials and methods: The medical records of all pregnant women followed by the obstetrics clinic between January 2010 and November 2012 were systematically evaluated, and patients with a diagnosis of GDM were identified. A total of 68 patients with GDM and 61 healthy controls were included in the study. Results of relevant laboratory parameters were recorded. Results: Out of all the parameters evaluated, mean values for platelet distribution width (PDW) and mean activities …


Detection Of Caga And Vaca Genotypes Of Helicobacter Pylori Isolates From A University Hospital In Ankara Region, Turkey, Ceren Erdoğdu, Zeynep Saribaş, Yakut Akyön Yilmaz Jan 2014

Detection Of Caga And Vaca Genotypes Of Helicobacter Pylori Isolates From A University Hospital In Ankara Region, Turkey, Ceren Erdoğdu, Zeynep Saribaş, Yakut Akyön Yilmaz

Turkish Journal of Medical Sciences

The cagA and vacA profiles and their association with clinical findings show a distinct geographical distribution. In the present study, we aimed to determine the cagA status and vacA allelic subtypes in strains isolated from a university hospital in Ankara and to evaluate their associations with histopathological and endoscopic findings. Materials and methods: A total of 120 H. pylori strains from stock cultures positive for the ureA gene were randomly included in the present study. Of these strains, cagA and vacA allelic subtypes (s1a, s1b, s2, m1, m2) were examined by polymerase chain reaction. Results: Of the 120 strains, 64 …


Epistaxis In Geriatric Patients, Alper Yüksel, Hani̇fi̇ Kurtaran, Ekrem Sai̇d Kankiliç, Nebi̇l Ark, Kadri̇ye Şeri̇fe Uğur, Mehmet Gündüz Jan 2014

Epistaxis In Geriatric Patients, Alper Yüksel, Hani̇fi̇ Kurtaran, Ekrem Sai̇d Kankiliç, Nebi̇l Ark, Kadri̇ye Şeri̇fe Uğur, Mehmet Gündüz

Turkish Journal of Medical Sciences

Epistaxis is a common emergency in otolaryngology. The aim of this study is to analyze the etiology, management, and accompanying disorders of epistaxis in geriatric patients by reviewing the literature Materials and methods: Data of 117 patients 65 years old and older who presented to the Department of Otorhinolaryngology with active epistaxis between 2004 and 2010 were retrospectively reviewed. Records were evaluated for age, sex, accompanying disorders, drug medication, detailed otorhinolaryngological findings, and management of epistaxis. Results: There were 67 women (57.26%) and 50 men (42.74%) with a mean age of 73.51 years (range: 65–90). Ninety-four (80.34%) patients had accompanying …


Indoor Air Quality In Primary Schools In Keçiören, Ankara, Mustafa Alparslan Babayi̇ği̇t, Bi̇lal Bakir, Ömer Faruk Tekbaş, Recai̇ Oğur, Abdullah Kiliç, Serdar Ulus Jan 2014

Indoor Air Quality In Primary Schools In Keçiören, Ankara, Mustafa Alparslan Babayi̇ği̇t, Bi̇lal Bakir, Ömer Faruk Tekbaş, Recai̇ Oğur, Abdullah Kiliç, Serdar Ulus

Turkish Journal of Medical Sciences

To increase the awareness of environmental risk factors by determining the indoor air quality status of primary schools. Materials and methods: Indoor air quality parameters in 172 classrooms of 31 primary schools in Keçiören, Ankara, were examined for the purpose of assessing the levels of air pollutants (CO, CO_2, SO_2, NO_2, and formaldehyde) within primary schools. Results: Schools near heavy traffic had a statistically significant mean average of CO and SO_2 (P < 0.05). The classrooms that had more than 35 students had higher and statistically significant averages of CO_2, SO_2, NO_2, and formaldehyde compared to classrooms that had fewer than 35 students (P < 0.05). Of all classrooms, 29% had 100 CFU/100 mL and higher concentrations of microorganisms, which were not pathogens. Conclusion: Indoor air quality management should continually be maintained in primary schools for the prevention and control of acute and chronic diseases, particularly considering biological and chemical pollution.


Urinary Tract Infection In Patients With Chronic Kidney Disease, Chih-Yen Hsiao, Hsing-Lin Lin, Yen-Ko Lin, Chao-Wen Chen, Yuan-Chia Cheng, Wei-Che Lee, Tzu-Chin Wu Jan 2014

Urinary Tract Infection In Patients With Chronic Kidney Disease, Chih-Yen Hsiao, Hsing-Lin Lin, Yen-Ko Lin, Chao-Wen Chen, Yuan-Chia Cheng, Wei-Che Lee, Tzu-Chin Wu

Turkish Journal of Medical Sciences

Chronic kidney disease (CKD) has become a burden of health care globally. However, data on epidemiology, clinical features, and outcomes of urinary tract infection (UTI) in this population are scarce. This study aims to retrospectively review such data. Materials and methods: A retrospective cohort study was conducted from 1 January 2005 to 31 December 2011 in patients with CKD requiring hospitalization. Patients who had upper and lower UTIs were compared for demography and clinical data. Logistic regression was used to assess which variables were associated with upper UTI. Results: A total of 276 bacteriuria patients were admitted to our ward …


Evaluation Of Outer Hair Cell Function And Medial Olivocochlear Efferent System In Patients With Type Ii Diabetes Mellitus, Hayri̇ye Karabulut, İsmai̇l Karabulut, Muharrem Dağli, Yildirim Ahmet Bayazit, Şule Bi̇len, Yusuf Aydin, Serdar Güler, İsmet Bayramoğlu Jan 2014

Evaluation Of Outer Hair Cell Function And Medial Olivocochlear Efferent System In Patients With Type Ii Diabetes Mellitus, Hayri̇ye Karabulut, İsmai̇l Karabulut, Muharrem Dağli, Yildirim Ahmet Bayazit, Şule Bi̇len, Yusuf Aydin, Serdar Güler, İsmet Bayramoğlu

Turkish Journal of Medical Sciences

This study was designed to investigate the function of outer hair cells and medial olivocochlear efferents in type II diabetes mellitus (DM). Materials and methods: There were 50 patients with type II DM and 51 age- and sex-matched healthy controls included in the study. Both groups were compared in terms of transient evoked otoacoustic emissions (TEOAEs), distortion product otoacoustic emissions (DPOAEs), and contralateral suppression of TEOAE. Results: Pure tone thresholds of the patients with type II DM were significantly higher than in the controls (P < 0.05). The TEOAE amplitudes at 1 kHz and at 1.5, 2, 3, 4, and 6 kHz signal-to-noise ratio amplitudes on DPOAE testing were significantly lower in the patients than controls (P < 0.05). There was no significant difference between the type II DM and control groups regarding contralateral suppression test results of TEOAEs. Conclusion: Type II DM seems to impact the auditory system at the cochlear level by affecting the functions of outer hair cells, and it results in elevation of the thresholds on audiometry and a decrease in the amplitudes of otoacoustic emissions.


Ocular Surface Culture Changes In Patients After Septoplasty, Mahmut Özkiriş, Zeli̇ha Kapusuz Gencer, Çi̇ğdem Kader, Levent Saydam Jan 2014

Ocular Surface Culture Changes In Patients After Septoplasty, Mahmut Özkiriş, Zeli̇ha Kapusuz Gencer, Çi̇ğdem Kader, Levent Saydam

Turkish Journal of Medical Sciences

To investigate the interrelationships between pre- and postoperative microbiological changes by taking samples from both eyes of 40 patients who underwent septoplasty due to septal deviation. Materials and methods: Forty patients diagnosed with septal deviation who underwent a septoplasty operation under general anesthesia were enrolled in this study. The study was conducted on 40 patients who met the inclusion criteria and attended follow-up visits. One day before the operation and 48 h after the operation, cultures were taken individually from the conjunctivas and puncta of both eyes and sent to the microbiology laboratory. Results: Patients who were candidates for nasal …


Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak Jan 2014

Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak

Turkish Journal of Medical Sciences

This study evaluates types of malaria and treatment success in a series of identified cases among individuals who were presumed to have travelled to regions where malaria is endemic. Materials and methods: In Sema Hospital, 25 cases of malaria (5 in women, 20 in men) were diagnosed during the 6-year period between 2006 and 2012. The mean age of the patients was 34.5 years. Diagnoses were established with thick and thin peripheral blood smears that were parasite-positive. These tests were then compared to the rapid diagnostic test based on Plasmodium falciparum histidine-rich protein 2. Results: All cases demonstrated fever beginning …


Right-Sided Double-Lumen Tubes: Need For Design Improvement And Better Insertion Technique?, Jean S. Bussieres, Jérôme Lemieux, Jacques Somma Jan 2014

Right-Sided Double-Lumen Tubes: Need For Design Improvement And Better Insertion Technique?, Jean S. Bussieres, Jérôme Lemieux, Jacques Somma

Turkish Journal of Medical Sciences

No abstract provided.


An Investigation Of Pulmonary Findings Of Crimean-Congo Haemorrhagic Fever Patients, Gülden Bi̇lgi̇n, Çi̇ğdem Ataman Hati̇poğlu, Şeri̇fe Altun, Cemal Bulut, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz Jan 2014

An Investigation Of Pulmonary Findings Of Crimean-Congo Haemorrhagic Fever Patients, Gülden Bi̇lgi̇n, Çi̇ğdem Ataman Hati̇poğlu, Şeri̇fe Altun, Cemal Bulut, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz

Turkish Journal of Medical Sciences

Crimean-Congo haemorrhagic fever (CCHF) generally affects many organs. In this study a retrospective evaluation of the pulmonary findings of CCHF patients was made. Materials and methods: The records of patients were retrospectively analysed. For each patient an evaluation was made of age, sex, occupation, place of residence, contact with ticks, smoking history, and pulmonary radiological and laboratory findings. A confirmed diagnosis of CCHF was made on determination by enzyme-linked immunosorbent assay or polymerase chain reaction. Results: Of the 128 patients, 48.4% were female. Symptoms of coughing were determined in 18% of patients, sputum in 4.7%, chest pain in 3.9%, dyspnoea …