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Turkish Journal of Medical Sciences

Journal

2014

Rat

Articles 1 - 4 of 4

Full-Text Articles in Medicine and Health Sciences

Effects Of Ozone Therapy And Taurine On Ischemia/Reperfusion-Induced Testicular Injury In A Rat Testicular Torsion Model, Tolga Reşat Aydos, Mehmet Murad Başar, Oğuz Kul, Hasan Tarik Atmaca, Tuba Uzunali̇oğlu, Üçler Kisa, Oğuzhan Eki̇n Efe Jan 2014

Effects Of Ozone Therapy And Taurine On Ischemia/Reperfusion-Induced Testicular Injury In A Rat Testicular Torsion Model, Tolga Reşat Aydos, Mehmet Murad Başar, Oğuz Kul, Hasan Tarik Atmaca, Tuba Uzunali̇oğlu, Üçler Kisa, Oğuzhan Eki̇n Efe

Turkish Journal of Medical Sciences

To investigate the effect of ozone and/or taurine treatment comparatively on testicular damage due to ischemia/reperfusion (I/R) injury in an experimental torsion model in rats. Materials and methods: Adult Wistar rats with and without torsion/detorsion were used. In order to monitor the effect of ozone and/or taurine treatment on testicular damage due to I/R injury, following histopathological investigation apoptotic indexes were scored by TUNEL method. Moreover, tumor necrosis factor receptor 1 (TNFR1), caspase 3, caspase 8, endothelial nitric oxide synthase (eNOS), tumor necrosis factor alpha (TNF\alpha), and cytochrome C immunostainings were performed and the levels of malondialdehyde, glutathione peroxidase, superoxide …


Chronic Moderate Alcohol Consumption Induces Inos Expression In The Penis: An Immunohistochemical Study, Süheyla Gonca, Yusufhan Yazir, Semi̇l Selcen Göçmez, Eki̇m Nur Dalçik, Ti̇jen Utkan, Hakki Dalçik Jan 2014

Chronic Moderate Alcohol Consumption Induces Inos Expression In The Penis: An Immunohistochemical Study, Süheyla Gonca, Yusufhan Yazir, Semi̇l Selcen Göçmez, Eki̇m Nur Dalçik, Ti̇jen Utkan, Hakki Dalçik

Turkish Journal of Medical Sciences

To investigate the effect of moderate alcohol consumption on metabolic alterations, inducible nitric oxide synthase (iNOS), immunohistochemical distribution, and morphological damage to penile erectile tissue in rats. Materials and methods: Male Wistar albino rats were divided into 2 groups. Group 1 rats (control group, n = 8) received tap water ad libitum, and group 2 rats (n = 8) were fed with 20% ethanol. Increasing levels of alcohol were given to the rats over 12 weeks. Immunohistochemistry was then performed using the avidin-biotin-peroxidase technique on 5-um thickness tissue sections. Stained sections were examined by imaging microscope. Results: Alcohol consumption resulted …


Comparison Of Intraarticular Bupivacaine And Levobupivacaine Injection In Rat Synovial Inflammation, Beki̇r Suat Kürkçüoğlu, Melahat Dönmez, Seher Altinel, Seda Banu Akinci, Fatma Saricaoğlu, Ülkü Aypar Jan 2014

Comparison Of Intraarticular Bupivacaine And Levobupivacaine Injection In Rat Synovial Inflammation, Beki̇r Suat Kürkçüoğlu, Melahat Dönmez, Seher Altinel, Seda Banu Akinci, Fatma Saricaoğlu, Ülkü Aypar

Turkish Journal of Medical Sciences

Both bupivacaine and levobupivacaine are local anesthetics with strong analgesic efficacy that can be used intraarticularly. The aim of this study was to compare the effects of intraarticular bupivacaine and levobupivacaine injection on inflammation in articular cartilage and the synovium of the rat knee joint. Materials and methods: Twenty Sprague-Dawley rats were injected in the right knee joint with 0.2 mL of bupivacaine, while 0.2 mL of levobupivacaine was injected into the left knee joint. Groups of 5 were sacrificed on days 1, 7, 14, and 21 after bupivacaine and levobupivacaine administration and knee joints were examined for subintimal fibrosis, …


Effect Of Ginkgo Biloba On Brain Volume After Carotid Artery Occlusion In Rats: A Stereological And Histopathological Study, Zeynep Aktürk, Ersan Odaci, Ayşe İki̇nci̇, Orhan Baş, Si̇nan Canpolat, Serdar Çolakoğlu, Osman Fi̇kret Sönmez Jan 2014

Effect Of Ginkgo Biloba On Brain Volume After Carotid Artery Occlusion In Rats: A Stereological And Histopathological Study, Zeynep Aktürk, Ersan Odaci, Ayşe İki̇nci̇, Orhan Baş, Si̇nan Canpolat, Serdar Çolakoğlu, Osman Fi̇kret Sönmez

Turkish Journal of Medical Sciences

This study investigated the effect of Ginkgo biloba (GB) on brain volume in cerebral ischemia induced by stopping carotid artery blood flow. Materials and methods: Twenty-four adult male rats were divided into 4 groups of 6 rats each. No procedure was performed on the control group. Ischemia was applied to the rats in the ischemia and ischemia + GB groups by clamping the arteria carotis communis for 30 min. The rats in the ischemia + GB group were given 100 mg/kg drops (Tebokan Fort Drop, Abdi İbrahim İlaç Sanayi A.Ş., Turkey) containing dry GB leaf extract orally, every day for …