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Articles 31 - 60 of 105
Full-Text Articles in Medicine and Health Sciences
The Effect Of Pregnancy On The Physical And Sexual Abuse Of Women That Presented To A State Hospital In Trabzon, Turkey, Murat Topbaş, Mesut Ünsal, Gamze Çan, Aynur Bacak, Şükrü Özgün
The Effect Of Pregnancy On The Physical And Sexual Abuse Of Women That Presented To A State Hospital In Trabzon, Turkey, Murat Topbaş, Mesut Ünsal, Gamze Çan, Aynur Bacak, Şükrü Özgün
Turkish Journal of Medical Sciences
Aim: To investigate the prevalence of the physical and sexual abuse of women before and during pregnancy, and to determine whether pregnancy affected the abuse of women. Materials and Methods: This study was performed at a state hospital in the Turkish city of Trabzon and included 762 women that gave birth between July and September 2004. A questionnaire was administered during a face-to-face interview to collect data on sociodemographic factors, exposure to abuse before and during pregnancy, and the women´s post-abuse attitudes. Data were analyzed using the McNemar and chi-square tests. Results: It was determined that 8.8% of the women …
Parental Knowledge And Practices Regarding Febrile Convulsions In Turkish Children, Ertan Kayseri̇li̇, Aycan Ünalp, Hurşi̇t Apa, Suna Asi̇lsoy, Murat Hizarcioğlu, Pami̇r Gülez, Hasan Agin
Parental Knowledge And Practices Regarding Febrile Convulsions In Turkish Children, Ertan Kayseri̇li̇, Aycan Ünalp, Hurşi̇t Apa, Suna Asi̇lsoy, Murat Hizarcioğlu, Pami̇r Gülez, Hasan Agin
Turkish Journal of Medical Sciences
Aims: Families with children afflicted with febrile convulsions must be given adequate information regarding seizures and fever, and they need emotional support and first-aid demonstrations. In this study, we aimed to determine parental knowledge and practices regarding febrile convulsions in Turkish children. Materials and Methods: Questionnaires were given to 122 parents whose children were admitted to the emergency service of Behçet Uz Children´s Hospital between July 2006 and April 2007 with febrile convulsion episodes. Sixty-three parents whose children had a febrile convulsion for the first time (Group 1) and 59 parents whose children had a recurrent febrile convulsion (Group 2) …
Ductal Carcinoma Of The Parotid Gland Coexisting With Pleomorphic Adenoma, Bi̇rol Ci̇velek, Ercan Demi̇rbağ, Tayyar Selçuk, Uğur Çakmak, Seli̇m Çelebi̇oğlu
Ductal Carcinoma Of The Parotid Gland Coexisting With Pleomorphic Adenoma, Bi̇rol Ci̇velek, Ercan Demi̇rbağ, Tayyar Selçuk, Uğur Çakmak, Seli̇m Çelebi̇oğlu
Turkish Journal of Medical Sciences
Benign tumors of the parotid gland such as pleomorphic adenoma present as a painless mass and pose no difficulty in diagnosis. It is very rare to find a benign mass coexisting with a malignant entity in the parotid gland. We present a case of pleomorphic adenoma coexisting with ductal carcinoma.
Mixed Medullary-Follicular Thyroid Carcinoma : A Report Of Two Cases, Özge Han, Tuba Ünal, Selda Seçki̇n, Sezer Kulaçoğlu
Mixed Medullary-Follicular Thyroid Carcinoma : A Report Of Two Cases, Özge Han, Tuba Ünal, Selda Seçki̇n, Sezer Kulaçoğlu
Turkish Journal of Medical Sciences
Mixed medullary-follicular carcinoma is an uncommon tumor of the thyroid. It is characterized by histological and immunohistochemical features of both follicular and parafollicular C cells. We report two female patients, aged 26 and 78 years, with mixed medullary-follicular carcinoma. Histologically, the tumors are composed of follicular carcinoma areas and solid nests of polygonal cells consistent with medullary carcinoma. Immunohistochemically, thyroglobulin and calcitonin positivity was detected. Precise diagnosis of mixed medullary-follicular carcinoma is essential for accurate treatment and follow-up.
Acute Intoxication By Endosulfan: Any Role Of N-Acetylcysteine Therapy?, Ahmet Demi̇rcan, Eli̇f Çalidağ, Murat Özsaraç, Ayfer Keleş, Fi̇kret Bi̇ldi̇k
Acute Intoxication By Endosulfan: Any Role Of N-Acetylcysteine Therapy?, Ahmet Demi̇rcan, Eli̇f Çalidağ, Murat Özsaraç, Ayfer Keleş, Fi̇kret Bi̇ldi̇k
Turkish Journal of Medical Sciences
Reactive oxygen species may play a role in the mediation of acetaminophen (APAP) hepatotoxicity. N-acetylcysteine (NAC) is the standard therapy for treatment of the APAP overdose patient. The suspected mechanism of hepatic injury appears to be similar to that of APAP and the empiric use of NAC may be justified, especially in significant endosulfan poisoning. An 18-year-old male presented to the emergency department because of unconsciousness and seizure that developed after acute intentional ingestion of endosulfan. Severe diaphoresis was noted and he had a Glasgow Coma Score of 7 (E1M4V2). Within 8 hours of his arrival in the emergency department, …
Twin Sisters With Unique Septate Uterus And Longitudinal Vaginal Septum, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Hi̇lal Yuvaci
Twin Sisters With Unique Septate Uterus And Longitudinal Vaginal Septum, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Hi̇lal Yuvaci
Turkish Journal of Medical Sciences
The septate uterus is the most common form of structural uterine anomalies. A rare developmental variant is a complete septate uterus with cervical duplication and a complete vaginal septum. Experiences with these unique uterine anomalies are limited only to case reports. Although there have been a few families in which members are affected similarly, there are no reports in the literature describing dizygotic twins with the same congenital uterine malformation, as seen in our cases. A 28-year-old woman and her dizygotic twin sister who had spontaneous abortion history were identified in our practice with complete septate uterus, cervical duplication and …
Purtscher´S Retinopathy: An Unusual Association With A Complicated Mandibular Fracture, Tongabay Cumurcu, Hüseyi̇n Yardim, Mehmet Güven, Raşi̇t Kiliç, Ni̇lüfer Özkan
Purtscher´S Retinopathy: An Unusual Association With A Complicated Mandibular Fracture, Tongabay Cumurcu, Hüseyi̇n Yardim, Mehmet Güven, Raşi̇t Kiliç, Ni̇lüfer Özkan
Turkish Journal of Medical Sciences
We present a case of unilateral traumatic retinal angiopathy following a mandibular fracture. An 11-year-old child involved in a bicycle accident developed Purtscher´s retinopathy in the left eye with retinal hemorrhages, cotton wool spots, and optic disc swelling on funduscopy. The visual acuity in this eye was counting fingers at one meter.
Generalized Choreoathetosis In An Acquired Immune Deficiency Syndrome Patient With Cerebral Toxoplasmosis, İpek Mi̇di̇, Hari̇ka G. Çalişkan, Zafer Toktaş, Aydin Sav, Di̇lek İ. Günal
Generalized Choreoathetosis In An Acquired Immune Deficiency Syndrome Patient With Cerebral Toxoplasmosis, İpek Mi̇di̇, Hari̇ka G. Çalişkan, Zafer Toktaş, Aydin Sav, Di̇lek İ. Günal
Turkish Journal of Medical Sciences
Many hypokinetic and hyperkinetic movement disorders (e.g. parkinsonism, chorea, myoclonus, dystonia) are associated with acquired immune deficiency syndrome (AIDS) and may sometimes represent the initial manifestation of the illness. We described a 37-year-old human immunodeficiency virus (HIV)-infected patient with generalized choreoathetoid movements associated with AIDS. Cranial MRI revealed multiple cerebral and cerebellar abscesses. The diagnosis of toxoplasmosis was established by brain biopsy. Hemichorea and hemiballismus in AIDS patients are pathognomonic findings of cerebral toxoplasmosis. Generalized choreiform movement is a rare condition and related to the bilateral cerebral involvement in toxoplasma disease affecting the subcortical structures.
Neural Tube Defects And 19 Bp Deletion Within Intron-1 Of Dihydrofolate Reductase Gene, Nejat Akar, Ece Akar, Yonca Eği̇n, Gülhi̇s Deda, Saadet Arsan, Mesi̇ha Eki̇m
Neural Tube Defects And 19 Bp Deletion Within Intron-1 Of Dihydrofolate Reductase Gene, Nejat Akar, Ece Akar, Yonca Eği̇n, Gülhi̇s Deda, Saadet Arsan, Mesi̇ha Eki̇m
Turkish Journal of Medical Sciences
Aims: Dihydrofolate reductase (DHFR) is necessary for the reduction of the ingested folates before they are used in the body metabolism. Thus, the DHFR enzyme has an important role in folate supplementation and the DHFR gene is a strong candidate for a teratogenic locus for neural tube defects (NTDs). There is a 19 bp deletion within the first intron of the DHFR gene, which may have an effect on folate reduction. We thus studied this mutation in Turkish spina bifida patients and their mothers to determine whether there is an association with the occurrence of NTD. Materials and Methods: The …
Pten Expression In Primary Prostate Carcinoma In Turkish Patients, Di̇lek Ertoy Baydar, Haluk Özen, Osman Saraçbaşi, Erdem Karabulut
Pten Expression In Primary Prostate Carcinoma In Turkish Patients, Di̇lek Ertoy Baydar, Haluk Özen, Osman Saraçbaşi, Erdem Karabulut
Turkish Journal of Medical Sciences
Aim: Prostatic adenocarcinoma shows remarkable variability in the incidence and biological behavior between populations from different races and geographical regions of the world. PTEN has been reported as the most commonly mutated tumor suppressor gene in prostate cancer. Incidence of PTEN alterations occurring in prostatic carcinoma has not been studied previously in the Turkish population. Materials and Methods: We examined PTEN protein expression immunohistochemically and its significance in 69 primary prostate cancer patients from Turkey. Two tissue microarrays constructed by 0.6 mm cores from radical prostatectomy specimens were used. Clinical information for all patients was obtained from hospital records. Results: …
Serum Dehydroepiandrosterone Sulfate Usage For Early Detection Of Prostate Cancer In Men With Serum Prostate Specific Antigen Level Between 2.5 And 4.0 Ng/Ml: A Pilot Study, Yilmaz Aslan, Ümi̇t Tekdoğan, Altuğ Tuncel, Meti̇n Burçi̇n Uzun, Erdem Karabulut, Ali̇ Atan
Serum Dehydroepiandrosterone Sulfate Usage For Early Detection Of Prostate Cancer In Men With Serum Prostate Specific Antigen Level Between 2.5 And 4.0 Ng/Ml: A Pilot Study, Yilmaz Aslan, Ümi̇t Tekdoğan, Altuğ Tuncel, Meti̇n Burçi̇n Uzun, Erdem Karabulut, Ali̇ Atan
Turkish Journal of Medical Sciences
Aims: We prospectively evaluated the diagnostic value of serum prostate specific antigen (PSA)-based diagnostic parameters and serum dehydroepiandrosterone sulfate (DHEAS) level for early detection of prostate cancer in patients with serum PSA level between 2.5 and 4 ng/ml. Materials and Methods: This study included 83 consecutive men with serum PSA levels between 2.5 and 4.0 ng/ml. All patients underwent transrectal ultrasound-guided prostate needle biopsy. Total PSA level, free/total PSA ratio, PSA density of the total volume (PSAD-TV), PSA density of the transition zone (PSAD-TZ), and serum DHEAS values were determined. Results: Seventy-four patients (89.2%) had histopathologically confirmed benign prostatic hyperplasia …
Oxidative Stress Of Radioiodine Treatment In Patients With Hyperthyroidism, Mustafa Yildiz, Ekrem Çi̇çek, Burçi̇n Aşkim Gümüş, Celal Çerçi̇, Süreyya Çerçi̇, Erol Eroğlu, Namik Deli̇baş
Oxidative Stress Of Radioiodine Treatment In Patients With Hyperthyroidism, Mustafa Yildiz, Ekrem Çi̇çek, Burçi̇n Aşkim Gümüş, Celal Çerçi̇, Süreyya Çerçi̇, Erol Eroğlu, Namik Deli̇baş
Turkish Journal of Medical Sciences
Aims: To investigate radiation-induced oxidative damage in erythrocytes after administration of radioiodine-131 (^{131}I) in patients with hyperthyroidism. Materials and Methods: Twenty patients with hyperthyroidism (11 F, 9 M) treated with ^{131}I were included into the study. Blood samples were taken from patients just before, 1 hour after and 3 hours after applying radioiodine. Malondialdehyde (MDA) and levels of antioxidant enzymes such as glutathione peroxidase (GPX), superoxide dismutase (SOD) and catalase (CAT) were measured to evaluate the radiation-induced oxidative damage. Results: We found that enzyme activities of SOD, GPX and CAT were decreased 1 hour and 3 hours after radioiodine treatment …
Functional Vitamin B12 Deficiency Represented By Elevated Urine Methylmalonic Acid Levels In Patients With Migraine, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe, Hakan Tekeli̇, Mehmet Güney Şenol
Functional Vitamin B12 Deficiency Represented By Elevated Urine Methylmalonic Acid Levels In Patients With Migraine, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe, Hakan Tekeli̇, Mehmet Güney Şenol
Turkish Journal of Medical Sciences
Aims: Although vitamin B12 is currently used as a treatment option in patients with migraine, a possible cobalamin deficiency in those patients has not yet been investigated. In this study, we aimed to investigate cobalamin metabolism in patients with migraine. Materials and Methods: Fifty women having migraine without aura were matched with healthy controls (n=6) with the same age distribution. Fasting serum vitamin B12, folate, plasma total homocysteine (tHcy) and first morning urine methylmalonic acid (MMA) levels were determined in patient and control groups. Statistical differences in laboratory parameters between patient and control groups were analyzed by SPSS for Windows …
Serum Transforming Growth Factor-Β (Tgf-Β), Matrix Metalloproteinase-2 (Mmp-2), Matrix Metalloproteinase-9 (Mmp-9) And Tissue Inhibitors Of Metalloproteinase (Timp-1) Levels In Childhood Asthma, Fi̇gen Doğu, Ali̇şan Yildiran, Deni̇z Güloğlu, Funda Erol Çi̇pe, Mutlu Yüksek, Emel Babacan, Aydan İki̇nci̇oğullari
Serum Transforming Growth Factor-Β (Tgf-Β), Matrix Metalloproteinase-2 (Mmp-2), Matrix Metalloproteinase-9 (Mmp-9) And Tissue Inhibitors Of Metalloproteinase (Timp-1) Levels In Childhood Asthma, Fi̇gen Doğu, Ali̇şan Yildiran, Deni̇z Güloğlu, Funda Erol Çi̇pe, Mutlu Yüksek, Emel Babacan, Aydan İki̇nci̇oğullari
Turkish Journal of Medical Sciences
Aims: Airway remodelling is a characteristic feature of asthma and is a dynamic process involving extracellular matrix (ECM) production and its degradation. In this regard, the matrix metalloproteinases (MMPs) and their specific inhibitors known as tissue inhibitors of metalloproteinases (TIMPs) have been shown to be important in this process. In the present study, transforming growth factor (TGF)-\beta, MMP-2, MMP-9 and TIMP-1 levels in serum samples of children with stable asthma and healthy controls were evaluated to determine whether these levels show any difference between asthmatic and healthy children and whether or not these levels change with atopic status. Materials and …
Hematological Complications In 787 Cases Of Acute Brucellosis In Eastern Turkey, İmdat Di̇lek, Ahmet Durmuş, Mustafa Kasim Karahocagi̇l, Hayretti̇n Akdeni̇z, Hasan Karsen, Ali̇ İrfan Baran, Ömer Evi̇rgen
Hematological Complications In 787 Cases Of Acute Brucellosis In Eastern Turkey, İmdat Di̇lek, Ahmet Durmuş, Mustafa Kasim Karahocagi̇l, Hayretti̇n Akdeni̇z, Hasan Karsen, Ali̇ İrfan Baran, Ömer Evi̇rgen
Turkish Journal of Medical Sciences
Aim: In this paper, we present the hematological findings of 787 cases diagnosed with acute brucellosis. Materials and Methods: Records of the cases seen between 1994 and 2006 were retrospectively investigated regarding hematological changes. Results: Three hundred sixty-five (46%) patients were male and 422 (54%) were female. Mean age was 32 (range: 11-78 years). Mean hematological values were as follows: Hb 12 g/dl (4-19), Htc 36% (12-56), leukocyte 6.9 x 10^9/L (0.5-25) and platelets 213 x 10^9/L (9-617). According to differential counts, 34% and 14% of patients had mononuclear cell and neutrophil dominance, respectively. Fifty-six percent of patients were found …
Classification Of Sigmoid Volvulus, S. Selçuk Atamanalp, Bülent Aydinli, Gürkan Öztürk, Mahmut Başoğlu, M. İlhan Yildirgan, Durkaya Ören, Abdul Meci̇t Kantarci
Classification Of Sigmoid Volvulus, S. Selçuk Atamanalp, Bülent Aydinli, Gürkan Öztürk, Mahmut Başoğlu, M. İlhan Yildirgan, Durkaya Ören, Abdul Meci̇t Kantarci
Turkish Journal of Medical Sciences
Aim: The aim of this study was to establish a classification that will aid in the surgical treatment and prognosis of sigmoid volvulus (SV). Materials and Methods: The records of 420 patients with SV who were treated surgically during a 41.5-year period were reviewed retrospectively. The preoperative and operative criteria that were significantly correlated with mortality were determined. Results: Of 420 patients, 68 (16.2%) died. Age over 60 years (P < 0.001), associated disease (P < 0.001), presence of shock (P < 0.001), and presence of sigmoid colon gangrene (P < 0.001) were significantly correlated with mortality. A classification was made using these criteria. Conclusions: Recommended treatment options and potential mortality rates were determined for each class in the new classification based on the evaluation of the present series, our clinical experience, and literature findings. This classification may be helpful in determination of the surgical treatment and prognosis of SV.
Abnormal Uterine Bleeding In Adolescents: Treatment With Combined Oral Contraceptive Pills Is Effective Even In Hospitalized Patients With Bleeding Disorders, M. Meti̇n Altay, Ali̇ Haberal
Abnormal Uterine Bleeding In Adolescents: Treatment With Combined Oral Contraceptive Pills Is Effective Even In Hospitalized Patients With Bleeding Disorders, M. Meti̇n Altay, Ali̇ Haberal
Turkish Journal of Medical Sciences
Aims: To show the efficacy of oral contraceptive (OC) treatment for hospitalized adolescent patients with abnormal uterine bleeding (AUB). Materials and Methods: Thirty-one girls with AUB and anemia hospitalized within the last two years were included. The patients´ medical records were evaluated retrospectively. All patients were given combined OC containing 0.03 mg ethinyl estradiol plus 0.15 mg desogestrel according to a defined protocol. Results: Among 31 patients, 8 (25.8%) had bleeding disorders: 3 (9.7%) had factor VII deficiency, 3 (9.7%) thrombocytopenia, 1 (3.2%) factor VIII deficiency and 1 (3.2%) von Willebrand disease. Vaginal bleeding stopped in all patients within a …
Assessment Of Mental Health Of University Students With Ghq-12, Sarp Üner, Hi̇lal Özcebe, T. Gökhan Telatar, Sabahat Tezcan
Assessment Of Mental Health Of University Students With Ghq-12, Sarp Üner, Hi̇lal Özcebe, T. Gökhan Telatar, Sabahat Tezcan
Turkish Journal of Medical Sciences
Aims: The aim of this study was to assess the mental health status of university students and the factors affecting their mental health. Materials and Methods: The universe of the study consisted of a total of 8407 students enrolled as first- or third-year students of a university. The study sample was determined by using the ``sampling size where the population in universe is known´´ formula. The study questionnaire was designed to include questions regarding some sociodemographic characteristics and the General Health Questionnaire (GHQ)-12. Data were analyzed by SPSS 15.0, and binary logistic regression forward selection method was used to determine …
A Study Of Learning Assessment Of Personal Hygiene Skills Of Mentally Retarded Individuals In Drop-In Day Care Services, Fi̇gen Ar, Esra Kiliç, Ayşegül Akbay Yarpuzlu
A Study Of Learning Assessment Of Personal Hygiene Skills Of Mentally Retarded Individuals In Drop-In Day Care Services, Fi̇gen Ar, Esra Kiliç, Ayşegül Akbay Yarpuzlu
Turkish Journal of Medical Sciences
Aim: The aim of the study was to assess the success and efficiency of the training practices for acquisition of basic personal hygiene skills and behavior of hand washing and soiling in a relatively heterogeneous group of individuals receiving care from a drop-in day care/special education service. We also analyzed etiologies of the causes of discrepancies in learning behavior implying a need for differentiation of intellectually disabled individuals who are candidates for continuous long-term institutional medical care from those who can be integrated into the community through special education. Materials and Methods: The study included 30 participants with mental retardation …
What Influences Herbal Medicine Use? - Prevalence And Related Factors, Serpi̇l Aydin, Ayfer O. Bozkaya, Mümtaz M. Mazicioğlu, Ayfer Gemalmaz, Ali̇s Özçakir, Ahmet Öztürk
What Influences Herbal Medicine Use? - Prevalence And Related Factors, Serpi̇l Aydin, Ayfer O. Bozkaya, Mümtaz M. Mazicioğlu, Ayfer Gemalmaz, Ali̇s Özçakir, Ahmet Öztürk
Turkish Journal of Medical Sciences
Aims: The use and cost of complementary/alternative medicine (CAM) has been gaining in importance worldwide. Herbal medicine is one of the most commonly used methods. To understand the effectiveness, reliability, and quality of CAM and provide standardization in its analysis, its prevalence and the factors influencing its use must be identified. This study was conducted to identify the prevalence of CAM use and the effective factors in our population. Materials and Methods: A stratified multistage probability sampling design was used in this cross-sectional, population-based study, which was conducted in Aydin. Participants were interviewed face to face by trained interviewers with …
Clinical And Rhinoscintigraphic Evaluation Of Oral Macrolides In The Management Of Sinonasal Polyposis, Emi̇ne Aydin, Hülya Ortapamuk, Hakan Korkmaz, Engi̇n Dursun, Adi̇l Eryilmaz, Güleser Saylam, Muharrem Dağli
Clinical And Rhinoscintigraphic Evaluation Of Oral Macrolides In The Management Of Sinonasal Polyposis, Emi̇ne Aydin, Hülya Ortapamuk, Hakan Korkmaz, Engi̇n Dursun, Adi̇l Eryilmaz, Güleser Saylam, Muharrem Dağli
Turkish Journal of Medical Sciences
Aim: To document the efficacy of low-dose long-term oral macrolide treatment in the management of sinonasal polyposis. The study was designed prospectively in a group of patients with sinonasal polyposis and negative history of surgery. Materials and Methods: Ten patients were administered roxithromycin (RXM) 150 mg/day single oral dose for eight weeks. All patients underwent Tc-99m rhinoscintigraphic evaluation of mucociliary activity and endoscopic evaluation before and after the treatments. Response to treatment, in terms of rhinoscintigraphic and endoscopic improvement, was assessed. Results: Of the 10 patients, 7 were male and 3 female, with an average age of 46 years (27-74). …
Ear Lobule Flap For Reconstruction Of A Near Total Auricle Defect, Bi̇rol Ci̇velek, Ercan Demi̇rbağ, Uğur Çakmak, Tayyar Selçuk, Seli̇m Çelebi̇oğlu
Ear Lobule Flap For Reconstruction Of A Near Total Auricle Defect, Bi̇rol Ci̇velek, Ercan Demi̇rbağ, Uğur Çakmak, Tayyar Selçuk, Seli̇m Çelebi̇oğlu
Turkish Journal of Medical Sciences
A number of surgical procedures can be performed for partial auricular defects occurring due to various causes. The most appropriate reconstruction method should be employed with regard to the defect dimensions and the status of local adjacent tissues. We present a case of near total excision of external ear due to recurrent basal cell carcinoma and the reconstruction of the defect with ear lobule flap.
The Anesthetic Approach In A Patient With Type I Neurofibromatosis With Multiple Deformities, Nurten İnan, Hülya Başar, Müge Türkoğlu, Handan Güleç, Esma Tezer, Bülent Baltaci
The Anesthetic Approach In A Patient With Type I Neurofibromatosis With Multiple Deformities, Nurten İnan, Hülya Başar, Müge Türkoğlu, Handan Güleç, Esma Tezer, Bülent Baltaci
Turkish Journal of Medical Sciences
von Recklinghausen disease is a type I neurofibromatosis originating from the nervous system. In this syndrome, there is abnormal deposition of neural tissue in the nervous system, endocrine system, visceral structures, and skin. We report the anesthetic management of a 31-year-old female patient with multiple thorax deformities who was diagnosed as von Recklinghausen disease. The patient was admitted to the Plastic and Reconstructive Surgery Department because of a huge subcutaneous neurofibroma on her right upper extremity. General anesthesia was considered a high risk for this patient on the basis of her laboratory results and physical findings. We planned brachial plexus …
Bilateral Galactocele In A Male Infant, Hakan Döneray, Behzat Özkan, Fazli Erdoğan, Ahmet Bedi̇i̇ Salman
Bilateral Galactocele In A Male Infant, Hakan Döneray, Behzat Özkan, Fazli Erdoğan, Ahmet Bedi̇i̇ Salman
Turkish Journal of Medical Sciences
Temporary breast enlargement may be seen in normal newborn and adolescent boys. Cysts of the breast are uncommon in childhood. Galactocele, defined as an encysted collection of milk products, is an extremely rare cause of breast enlargement in infants and children. We herein report a male infant with bilateral galactocele who was otherwise healthy, and we also review the literature.
Unexpected Complication Due To Shigella Flexneri In A Child: Acute Appendicitis, Cüneyt Tayman, Alparslan Tonbul, Emi̇n Mete, Ferhat Çatal, Burhan Köseoğlu
Unexpected Complication Due To Shigella Flexneri In A Child: Acute Appendicitis, Cüneyt Tayman, Alparslan Tonbul, Emi̇n Mete, Ferhat Çatal, Burhan Köseoğlu
Turkish Journal of Medical Sciences
Acute bacillary dysentery (shigellosis) occurs due to infections with shigella sp. The spectrum of acute shigellosis ranges from mild watery diarrhea to severe dysentery. Surgical complications of shigellosis described in children have included appendicitis with or without perforation, colonic perforation, intestinal obstruction, and intraabdominal abscess. Acute appendicitis and infective diarrheal illness can be difficult to differentiate, particularly in children. Thus, patients must be followed up closely until the differentiation between bacterial gastroenteritis and acute appendicitis can be made. We report herein a 10-year-old boy who had acute appendicitis due to Shigella flexneri.
Dermatomyositis Associated With Hemophagocytic Syndrome: A Case Report/Review Of The Literature, Engi̇n Sennaroğlu, Berçem Ayçi̇çek Doğan, Hasan Tunca, Bariş Yilmaz, Gamze Gedi̇k, Burak Ci̇velek, Si̇nem Tümtürk
Dermatomyositis Associated With Hemophagocytic Syndrome: A Case Report/Review Of The Literature, Engi̇n Sennaroğlu, Berçem Ayçi̇çek Doğan, Hasan Tunca, Bariş Yilmaz, Gamze Gedi̇k, Burak Ci̇velek, Si̇nem Tümtürk
Turkish Journal of Medical Sciences
Hemophagocytic syndrome (HPS) is a disorder that might be transferred genetically due to an autosomal recessive genetic defect of the long arm of chromosome 9 and chromosome 10 (9q21.3-22 and 10q21-22), termed as primary hemophagocytic syndrome (PHPS) or familial hemophagocytic hemophagocytosis (FHPS) and it may be associated with a variety of infections, malignant neoplasms, drugs, autoimmune diseases and various immuno deficiencies, termed as secondary hemophagocytic syndrome (SHPS). For most patients with HPS, the outcome is rapid and fatal unless the diagnosis is made early and followed by prompt therapeutic intervention. Fever, hepatosplenomegaly, cytopenia, hypertriglyceridemia and/or hypofibrinogenemia, low erythrocyte sedimentation rate, …
Coexistence Of Tuberculosis Verrucosa Cutis With Scrofuloderma, Müzeyyen Gönül, Ülker Gül, Arzu Kiliç, Seçi̇l Soylu, Murat Demi̇ri̇z, Ayhan Kubar
Coexistence Of Tuberculosis Verrucosa Cutis With Scrofuloderma, Müzeyyen Gönül, Ülker Gül, Arzu Kiliç, Seçi̇l Soylu, Murat Demi̇ri̇z, Ayhan Kubar
Turkish Journal of Medical Sciences
Although cutaneous tuberculosis is rarely seen in developed countries, it is still commonly seen in developing countries. Tuberculosis verrucosa cutis (TVC) is a form of cutaneous tuberculosis that is caused by direct inoculation of Mycobacterium tuberculosis into the skin through open wounds or abrasions in sensitized individuals and is rarely seen in our country. Scrofuloderma is a form of cutaneous tuberculosis that occurs by direct spread of Mycobacterium tuberculosis from a contiguous structure. Coexistence of TVC and scrofuloderma is extremely rare. A 35-year-old woman presented to our clinic with a lesion on the dorsum of her left hand. Dermatological examination …
Is Cd117 Expression Related With Plasma Cell Differentiation, Irf4/Mum1 And Cd38 Expressions In Lymphoid Neoplasms?, Gülşah Kaygusuz, Işinsu Kuzu, Saba Ki̇remi̇tçi̇, Duygu Kankaya, Zeynep Biyikli
Is Cd117 Expression Related With Plasma Cell Differentiation, Irf4/Mum1 And Cd38 Expressions In Lymphoid Neoplasms?, Gülşah Kaygusuz, Işinsu Kuzu, Saba Ki̇remi̇tçi̇, Duygu Kankaya, Zeynep Biyikli
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to assess the expression of CD117 in a large series of both Hodgkin´s and non-Hodgkin´s lymphoma, and to investigate the association between the expression patterns of CD117, IRF4/MUM1, and CD38. Materials and Methods: A total of 237 lymphoma cases were selected and examined within six tissue microarray paraffin blocks. Immunohistochemistry was performed using antibodies against CD117, IRF4/MUM1 and CD38. Results: CD117 and IRF4/MUM1 immunoreactivity were seen in a subset of high-grade and low-grade B-cell lymphomas, as well as T-cell lymphomas and classical type Hodgkin´s lymphomas. CD38 positivity was only detected in 1% of diffuse …
The Effect Of Erythropoietin On Neurotrophic Factors In N9 Murine Microglial Cells, Fi̇li̇z Kuralay, Başak Bi̇ngöl Çakirli, Şermi̇n Genç
The Effect Of Erythropoietin On Neurotrophic Factors In N9 Murine Microglial Cells, Fi̇li̇z Kuralay, Başak Bi̇ngöl Çakirli, Şermi̇n Genç
Turkish Journal of Medical Sciences
Aim: In this study, we investigated whether interferon gamma (IFN\gamma), lipopolysaccharides (LPS) and amyloid beta (AMY\beta), as toxic stimulator agents, and erythropoietin (EPO), as a neurotrophic agent, have an effect on the production of the following neurotrophic factors in the N9 murine microglia cell line: neurotrophin 3 (NT3), neurotrophin 4 (NT4), and brain-derived neurotrophic factor (BDNF). Materials and Methods: Microglial cells were incubated with 50 μg/ml AMY\beta, or 1 μg/ml of LPS plus 100 U/ml recombinant murine IFN\gamma, and/or one of three different concentrations (0.1, 1.0, and 5.0 U/ml) of recombinant mouse EPO for 24 h. Results: EPO 0.1 U/ml …
The Effect Of Caffeic Acid Phenethyl Ester (Cape) Treatment On Levels Of Mda, No And Antioxidant Enzyme Activities In Retinas Of Streptozotocin-Induced Diabetic Rats, Mustafa Durmuş, H. Ramazan Yilmaz, Efkan Uz, Nurten Özçeli̇k
The Effect Of Caffeic Acid Phenethyl Ester (Cape) Treatment On Levels Of Mda, No And Antioxidant Enzyme Activities In Retinas Of Streptozotocin-Induced Diabetic Rats, Mustafa Durmuş, H. Ramazan Yilmaz, Efkan Uz, Nurten Özçeli̇k
Turkish Journal of Medical Sciences
Aim: This study was performed to determine the effect of caffeic acid phenethyl ester (CAPE) treatment on levels of malondialdehyde (MDA) and nitric oxide (NO) and activities of antioxidant enzymes in retinas of streptozotocin (STZ)-induced diabetic rats. Materials and Methods: Twenty-seven rats were enrolled and divided into three groups: group 1: non-diabetic rats as control (n = 9); group 2: STZ-induced, untreated diabetic rats (n = 8); and group 3: STZ-induced, CAPE-treated diabetic rats (n = 10). Levels of MDA and NO and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in retinal tissues were analyzed. Results: In …