Medicine and Health Sciences Commons^™

Evaluation Of A Complexity-Based Morphosyntactic Treatment For Children With Language Disorders Of Mixed Etiologies, Kirsten M. Russell

Faculty Publications

Language disorder is characterized by difficulty with the comprehension and production of different aspects of language. School-aged children with developmental language disorder (DLD) and school-aged children with Down syndrome (DS) demonstrate similar deficits in the area of morphosyntax, which often creates barriers during social interactions and for academic learning. Although affected children may receive intervention, progress can be slow. Selecting appropriate treatment targets is critical for effective intervention. Traditional approaches for selecting treatment targets are based on developmental readiness (i.e., developmental) or functional need (i.e., remedial). However, intervention utilizing targets selected by these methods produce only modest results, despite a …

Corticosteroid-Laba Inhalers Increase Phonation Threshold Pressure (Ptp) And Flow (Ptf) In Rabbits, Christopher Dromey, Kristine Tanner, Heidi J. Robison, Maya Elena Stevens, Ray M. Merrill, Julie Barkmeier-Kraemer, Ben Christensen

Faculty Publications

Objectives: This study examined the effects of a combination corticosteroid plus long-acting beta2-adrenergic agonist inhaler (IC) on rabbit phonation. Methods: White New Zealand male rabbits were assigned randomly to experimental and control groups (n = 11 per group). The experimental group received twice-daily doses of Advair HFA™ (fluticasone propionate 45 mcg and salmeterol 21 mcg) via a veterinary facemask with 1-way valve and spacer; the control group received aerosolized saline. After 8 weeks, animals were euthanized, larynges excised, frozen, and subsequently thawed and mounted on a standard bench apparatus. Phonation was elicited during 15 successive trials, and phonation threshold pressure …

Teaching Non-Native Sound Contrasts Using Visual Biofeedback, Shawn L. Nissen

Faculty Publications

This demonstration will explain how non-native sound contrasts can be taught to second language (L2) learners using real-time visual biofeedback through an electropalatographic (EPG) sensor. How the EPG sensor is created from a dental mold and is subsequently produced will be shown during the presentation. An explanation of how a student can visualize the contact patterns of their speech and how a tutor might use the various features of the associated software to customize the instruction to an individual speaker will be illustrated during the presentation. Possible limitations, costs, and drawbacks to using the technology will also be discussed.

Pattern-Based Target Selection For Treatment Of Irregular Past Tense: A Single-Case Experimental Design For Children With Developmental Language Disorder, Kirsten M. Russell, Amy Wilder, Julie L. Wambaugh

Faculty Publications

Purpose: Many children with developmental language disorder (DLD) demonstrate
difficulty inflecting irregular past tense verbs. We evaluated using phonological-
based patterns (i.e., schemas) to select targets for treatment of irregular verb inflection for children with DLD. We hypothesized this approach would result in acquisition of treated verbs, generalization to untreated verbs within the same phonological schema, and increased use of correct irregular verbs in naturalistic contexts. Method: Treatment was provided to three 7-year-old participants with DLD in the context of multiple baseline designs across behaviors and participants. Phonological schemas included vowel change, final alveolar, and dual change irregular verbs. Treatment …

Similar Overall Expression, But Different Profiles, Of Autistic Traits, Sensory Processing, And Mental Health Between Young Adult Males And Females, Garrett Cardon

Faculty Publications

Recent trends suggest that autism is more common in females than traditionally held. Additionally, some argue that females express autistic traits differently than males. Dimensional views of autism could shed light on these issues, especially with regards to understudied behavioral areas, such as sensory processing. We examined autistic traits, sensory processing, anxiety, and related behaviors in a large sample of neurotypical young adult males and females (n = 1122; 556 female; ages 19–26). Participants completed an online survey containing questionnaires related to the above. Between groups statistical analyses, as well as within groups correlations and mediation analyses containing these constructs …

Uncertainty, Sensory Processing, And Stress In Autistic Children During The Covid-19 Pandemic, Garrett Cardon, Mollie Bradley

Faculty Publications

Background: COVID-19 increased uncertainty for most and was especially disruptive to autistic people and their families, due in part to tendencies toward intolerance for uncertainty across this population. As such, COVID presented a natural experiment of uncertainty and its correlates in autism. Previous reports have shown associations between intolerance of uncertainty, sensory difficulty, and stress. Aims: We investigated changes in sensory difficulties and stress associated with COVID-related increases in uncertainty. Methods and procedures: Primary caregivers of 47 autistic children (ages 6–15) completed online surveys containing questions about demographics, experiences, and supports received during the pandemic. Additionally, caregivers filled out measures …

Similar Overall Expression, But Different Profiles, Of Autistic Traits, Sensory Processing, And Mental Health Between Young Adult Males And Females, Garrett Cardon, Miranda Mcquarrie, Savanah Calton, Terisa P. Gabrielsen

Faculty Publications

Recent trends suggest that autism is more common in females than traditionally held. Additionally, some argue that females express autistic traits differently than males. Dimensional views of autism could shed light on these issues, especially with regards to understudied behavioral areas, such as sensory processing. We examined autistic traits, sensory processing, anxiety, and related behaviors in a large sample of neurotypical young adult males and females (n = 1122; 556 female; ages 19–26). Participants completed an online survey containing questionnaires related to the above. Between groups statistical analyses, as well as within groups correlations and mediation analyses containing these constructs …

Perceived Covid-19 Threat, Perceived Healthcare System Inequities, Personal Experiences Of Healthcare Discrimination And Their Associations With Covid-19 Preventive Behavioral Intentions Among College Students In The Us, Juliana S. Sherchan, Jessica R. Fernandez, Shan Qiao, Arie W. Kruglanski, Allana T. Forde

Faculty Publications

College students are often reluctant to follow U.S. preventive guidelines to lower their risk of COVID-19 infection, despite an increased risk of transmission in college settings. Prior research suggested that college students who perceived greater COVID-19 severity and susceptibility (i.e., COVID-19 threat) were more likely to engage in COVID-19 preventive behaviors, yet there is limited research examining whether perceived COVID-19 threat, perceived U.S. healthcare system inequities, and personal experiences of healthcare discrimination collectively influence college students’ COVID-19 preventive behaviors. This study identified latent classes of perceived COVID-19 threat, perceived U.S. healthcare system inequities, and personal experiences of healthcare discrimination, examined …

Relationship Between Live-In Grandparents And Grandchild’S Health And Well-Being In Palestinian Refugees In Lebanon, Olfat B. Sheikomar, Hala Ghattas Ph.D., Nadine R. Sahyoun

Faculty Publications

Grandparents (GP) play influential roles in grandchildren’s health, behavior, and life. However, this relationship has not been examined in the Arab region. This study assesses whether the presence of GP in the household is associated with grandchildren’s health and wellbeing. Health status was determined by a child experiencing chronic health conditions or an acute illness, and wellbeing was determined based on school attendance and child labor. Data were collected through surveys conducted in 2010 and 2015 of representative samples of Palestinian refugees living in Lebanon. Multivariate logistic regression showed that, even after controlling for potential confounders, including the presence of …

Editorial: Sustainability Of Physical Activity Interventions And Public Health, Erica Y. Lau, Maureen C. Ashe, Sharon E. Taverno, Russell R. Pate Ph.D.

Faculty Publications

No abstract provided.

Women's Power In Hospital-Based Nursing: A Critical Qualitative Study, Kaitlyn C. George, Bret Lyman, Andy Pilarte Alcantara, Maya Stephenson

Faculty Publications

Aim: To understand the factors that affect power in hospital-based nursing and reveal how the female gender affects an individual's ability to feel empowered.

Design: Critical qualitative research design.

Method: Semi-structured interviews were conducted with nurses working in inpatient hospital settings in Utah and New Mexico. Data were collected from February to March 2022. Interviews were analysed using thematic analysis.

Results: Sixteen participants were interviewed. Six themes were identified from the data, four of which related to nurses' power at work, and two of which specifically related to how gender affects a nurse's ability to use power and feel empowered. …

Association Of Chronic Kidney Disease With Prior Tinnitus: A Case-Control Study, Shih-Han Hung, Sudha Xirasagar Mbbs., Ph.D., Yen-Fu Cheng, Nai-Wen Kuo, Herng-Ching Lin

Faculty Publications

This population-based, case-control study aims to explore the relationship between prior tinnitus and the occurrence of chronic kidney disease (CKD) using a nationwide, population-based cohort study. We used data from the Taiwan National Health Insurance Research Database to explore the association of CKD with tinnitus. We identified 15,314 patients aged >= 40 years old with a first-time diagnosis of CKD as the cases. We used propensity-scored matching to select 45,942 controls (1:3 ratio). We performed multivariate logistic regression to estimate the odds ratio (OR) of a prior tinnitus diagnosis among the CKD group vs. the control group. Analysis showed that …

Association Of Chlorhexidine Use And Scaling And Root Planing With Birth Outcomes In Pregnant Individuals With Periodontitis: A Systematic Review And Meta-Analysis, Maxwell Akonde, Rajat Das Gupta, Maxwell Akonde, Mark Reynolds, Stephanie Smith-Warner, Jihong Liu Sc.D., Fouzia Tarannum, James Beck, Donald Mattison

Faculty Publications

Importance Chlorhexidine mouthwash enhances treatment effects of conventional periodontal treatment, but data on chlorhexidine as a source of heterogeneity in meta-analyses assessing the treatment of maternal periodontitis in association with birth outcomes are lacking.

Objective To assess possible heterogeneity by chlorhexidine use in randomized clinical trials (RCTs) evaluating the effect of periodontal treatment (ie, scaling and root planing [SRP]) vs no treatment on birth outcomes.

Data Sources Cochrane Oral Health’s Trials Register, Cochrane Pregnancy and Childbirth’s Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE Ovid, Embase Ovid, LILACS BIREME Virtual Health Library (Latin American and Caribbean Health Science …

Association Of Chlorhexidine Use And Scaling And Root Planing With Birth Outcomes In Pregnant Individuals With Periodontitis: A Systematic Review And Meta-Analysis, Anwar T. Nerchant, Rajat Das Gupta, Maxwell Akonde, Mark Reynolds, Stephanie Smith-Warner, Jihong Liu, Fouzia Tarannum, James Beck, Donald Mattison

Faculty Publications

Importance Chlorhexidine mouthwash enhances treatment effects of conventional periodontal treatment, but data on chlorhexidine as a source of heterogeneity in meta-analyses assessing the treatment of maternal periodontitis in association with birth outcomes are lacking.

Objective To assess possible heterogeneity by chlorhexidine use in randomized clinical trials (RCTs) evaluating the effect of periodontal treatment (ie, scaling and root planing [SRP]) vs no treatment on birth outcomes.

Data Sources Cochrane Oral Health’s Trials Register, Cochrane Pregnancy and Childbirth’s Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE Ovid, Embase Ovid, LILACS BIREME Virtual Health Library (Latin American and Caribbean Health Science …

A Bayesian Susceptible-Infectious-Hospitalized-Ventilated-Recovered Model To Predict Demand For Covid-19 Inpatient Care In A Large Healthcare System, Stella Coker Watson Self Ph.D., Ms, Rongjie Huang, Shrujan Amin, Joseph Ewing, Carolina Rudisill, Alexander C. Mclain Ph.D.

Faculty Publications

The COVID-19 pandemic has strained healthcare systems in many parts of the United States. During the early months of the pandemic, there was substantial uncertainty about whether the large number of COVID-19 patients requiring hospitalization would exceed healthcare system capacity. This uncertainty created an urgent need to accurately predict the number of COVID-19 patients that would require inpatient and ventilator care at the local level. As the pandemic progressed, many healthcare systems relied on such predictions to prepare for COVID-19 surges and to make decisions regarding staffing, the discontinuation of elective procedures, and the amount of personal protective equipment (PPE) …

A Bayesian Susceptible-Infectious-Hospitalized-Ventilated-Recovered Model To Predict Demand For Covid-19 Inpatient Care In A Large Healthcare System, Stella Coker Watson Self Ph.D., Ms, Rongjie Huang, Shrujan Amin, Joseph Ewing, Caroline Rudisill, Alexander C. Mclain

Faculty Publications

The COVID-19 pandemic has strained healthcare systems in many parts of the United States. During the early months of the pandemic, there was substantial uncertainty about whether the large number of COVID-19 patients requiring hospitalization would exceed healthcare system capacity. This uncertainty created an urgent need to accurately predict the number of COVID-19 patients that would require inpatient and ventilator care at the local level. As the pandemic progressed, many healthcare systems relied on such predictions to prepare for COVID-19 surges and to make decisions regarding staffing, the discontinuation of elective procedures, and the amount of personal protective equipment (PPE) …

Survival Of Epithelial Ovarian Cancer In Black Women: A Society To Cell Approach In The African American Cancer Epidemiology Study (Aaces), Joellen M. Schildkraut, Courtney Johnson, Lauren F. Dempsey, Bo Qin, Paul Terry, Maxwell Akonde, Edward S. Peters, Hannah Mandle, Michele L. Cote, Lauren Peres, Patricia Moorman, Ann G. Schwartz, Micheal Epstein, Jeffrey Marks, Melissa Bondy, Andrew B. Lawson, Anthony Alberg, Elisa V. Bandera

Faculty Publications

Purpose

The causes for the survival disparity among Black women with epithelial ovarian cancer (EOC) are likely multi-factorial. Here we describe the African American Cancer Epidemiology Study (AACES), the largest cohort of Black women with EOC.

Methods

AACES phase 2 (enrolled 2020 onward) is a multi-site, population-based study focused on overall survival (OS) of EOC. Rapid case ascertainment is used in ongoing patient recruitment in eight U.S. states, both northern and southern. Data collection is composed of a survey, biospecimens, and medical record abstraction. Results characterizing the survival experience of the phase 1 study population (enrolled 2010–2015) are presented.

Results …

Investigating The Relationships Between Concentrated Disadvantage, Place Connectivity, And Covid-19 Fatality In The United States Over Time, Fengrui Jing, Zhenlong Liu, Shan Qiao, Jiajia Zhang Ph.D., Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Background Concentrated disadvantaged areas have been disproportionately affected by COVID-19 outbreak in the United States (US). Meanwhile, highly connected areas may contribute to higher human movement, leading to higher COVID-19 cases and deaths. This study examined the associations between concentrated disadvantage, place connectivity, and COVID-19 fatality in the US over time. Methods Concentrated disadvantage was assessed based on the spatial concentration of residents with low socioeconomic status. Place connectivity was defined as the normalized number of shared Twitter users between the county and all other counties in the contiguous US in a year (Y = 2019). COVID-19 fatality was measured …

Association Of Fabry Disease With Hearing Loss, Tinnitus, And Sudden Hearing Loss: A Nationwide Population-Based Study, Yen-Fu Cheng, Sudha Xirasagar Mbbs., Ph.D., Chin-Shyan Chen, Dau-Ming Niu, Herng-Ching Lin

Faculty Publications

Hearing loss and the related otologic manifestations are receiving increased scrutiny as significant causes of morbidity in Fabry disease. However, the relative risks of auditory deficits among patients with Fabry disease relative to the general population without a diagnosis of Fabry disease have not been studied. This study aims to explore the associations between Fabry disease and hearing-related manifestations using a nationwide population-based dataset. We identified study patients for this cross-sectional study from the 2015–2017 claims databases of the Taiwan Longitudinal Health Insurance Database 2005. We first identified 2312 patients aged over 20 years with a diagnosis of Fabry disease. …

The Hypertension Cascade Of Care In The Midst Of Conflict: The Case Of The Gaza Strip, Bassam A. Abu Hamad, Zeina Jamaluddine, Gloria Safadi, Marie Elizabeth Ragi, Raeda El Sayed Ahmad, Eszter P. Vamos, Sanjay Basu, John S. Yudkin, Mohammed Jawad, Christopher Millett, Hala Ghattas Ph.D.

Faculty Publications

Although hypertension constitutes a substantial burden in conflict-affected areas, little is known about its prevalence, control, and management in Gaza. This study aims to estimate the prevalence and correlates of hypertension, its diagnosis and control among adults in Gaza. We conducted a representative, cross-sectional, anonymous, household survey of 4576 persons older than 40 years in Gaza in mid-2020. Data were collected through face-to-face interviews, anthropometric, and blood pressure measurements. Hypertension was defined in anyone with an average systolic blood pressure ≥140 mmHg or average diastolic blood pressure ≥90 mmHg from two consecutive readings or a hypertension diagnosis. The mean age …

Pre-Existing Diabetes Mellitus, Hypertension And Kidneydisease As Risk Factors Of Pre-Eclampsia: A Disease Of Theories And Its Association With Genetic Polymorphism, Abdullah Salah Alanazi, Francis Victor, Kanwal Rehman, Yusra Habib Khan, Ismaeel Yunusa Ph.D., Abdulaziz Alzarea, Muhammad Sajid Hamid Akash, Tauqeer Hussain Mallhi

Faculty Publications

Pre-existing diabetes, hypertension and kidney disorders are prominent risk factors of pre-eclampsia (PE). It is a multifactorial pregnancy disorder associated with high blood pressure, proteinuria, and multiorgan failure, which develops after the 20th week of pregnancy. It is one of the most feared pregnancy disorders, as it consumes thousands of fetomaternal lives per annum. According to clinical and pathological studies, the placenta appears to be a key player in the pathogenesis of PE; however, the exact origin of this disorder is still under debate. Defective placentation and angiogenesis are the hallmarks of PE progression. This angiogenic imbalance, together with maternal …

Effects Of A Behavioral Intervention On Physical Activity, Diet, And Health-Related Quality Of Life In Pregnant Women With Elevated Weight: Results Of The Hipp Randomized Controlled Trial, Sarah Wilcox Phd, Jihong Liu, Gabrielle Turner-Mcgrievy Ph.D., Rd, Alycia K. Boutte, Ellen Wingard Msph, Rd, Ld

Faculty Publications

Background

Physical activity (PA), diet, and health-related quality of life (HRQOL) are related to maternal and infant health, but interventions to improve these outcomes are needed in diverse pregnant women with elevated weight.

Methods

Health In Pregnancy and Postpartum (HIPP) was a randomized controlled trial. Women who were pregnant (N=219, 44% African American, 56% white) with overweight or obesity but otherwise healthy were randomized to a behavioral intervention grounded in Social Cognitive Theory (n=112) or to standard care (n=107). The intervention group received an in-depth counseling session, a private Facebook group, and 10 content-based …

Effects Of A Behavioral Intervention On Physical Activity, Diet, And Health-Related Quality Of Life In Pregnant Women With Elevated Weight: Results Of The Hipp Randomized Controlled Trial, Sara Wilcox Ph.D., Jihong Liu, Gabrielle Turner-Mcgrievy Ph.D., Rd, Alycia K. Boutté, Ellen Wingard

Faculty Publications

Background

Physical activity (PA), diet, and health-related quality of life (HRQOL) are related to maternal and infant health, but interventions to improve these outcomes are needed in diverse pregnant women with elevated weight.

Methods

Health In Pregnancy and Postpartum (HIPP) was a randomized controlled trial. Women who were pregnant (N=219, 44% African American, 56% white) with overweight or obesity but otherwise healthy were randomized to a behavioral intervention grounded in Social Cognitive Theory (n=112) or to standard care (n=107). The intervention group received an in-depth counseling session, a private Facebook group, and 10 content-based …

The Fan Program Plan: Creating A Healthy Church Environment For Physical Activity And Healthy Eating, John A. Bernhart Ph.D., Mph, Ches, Caroline G. Dunn, Sara Wilcox Phd, Jessica Stucker, Deborah Kinnard

Faculty Publications

Background: Faith, Activity, & Nutrition (FAN) helps churches create a healthier environment for physical activity (PA) and healthy eating (HE) through policy, systems, and environmental changes. Objective: The purpose of this paper is to describe the implementation, evaluation, and revision of the FAN Program Plan across a two-phase study to help churches create guidelines and policies for PA and HE. Methods: In Phase 1, church committees attended trainings led by Community Health Advisors (CHA) where they assessed current practices to PA and HE. Committees used the FAN Program Plan to outline an implementation plan to increase opportunities, programs, messages, pastor …

Covid-19 Vaccination In Africa: A Case Of Unsatisfied Expectation And Ill-Preparedness, Osmond C. Ekwebelem, Phemelo Tamasiga, Abullhai Tunde Abonde, Ismaeel Yunusa Ph. D., Uju Nwauzoma, Helen Onyeaka

Faculty Publications

With a population of 1.3 billion people, of which 56% reside in rural settings, Africa seemed ill-prepared to handle the distribution of a COVID-19 vaccine. In addition, the capacity needed for a successful COVID- 19 vaccination campaign in Africa surpassed the available resources in local and state health agencies. As a result, African governments were advised to coordinate resources, health officials, and vaccinators, including local health practitioners, medical technicians, and pharmacists for the largest-ever vaccination campaign in Africa. Although the rolling out of the SARS-COV-2 vaccine was, as expected, slow in many African countries, and not yet enough to cover …

What Does It Mean To Take Online Classes As An International Student During Covid-19?, Katie K. Koo, Mei Jiang

Faculty Publications

Using the Theory of Social Support and the Community of Inquiry as theoretical frameworks, this qualitative study explored international students’ experiences, challenges, and perceptions of online learning environments during the COVID-19 pandemic in the United States. By conducting three virtual focus group interviews with 18 international students, we identified four key themes that encapsulate participants’ challenges and experiences of online learning: social isolation in online learning spaces, difficulties with engaging in online class discussions and activities, limited opportunities for improving English proficiency in the online setting and limited academic support from faculty and advisors. Implications for research and practice to …

Shifting Our Lens: Practical Trauma-Informed Approaches For Educators, Charity Garcia, Ingrid Weiss Slikkers, Tara Bailey

Faculty Publications

No abstract provided.

Epidemiology, Outcomes And Tolerability Of Protracted Treatment Of Nontuberculous Mycobacterial Infections At A Community Teaching Hospital In The Southeastern United States, Yuwei Vivian Tsai, Carolina Derrick, Ismaeel Yunusa Ph.D., Sharon Weissman, Majdi N. Al-Hasan, Julie Ann Justo Pharm.D., P. Brandon Bookstaver Pharm.D.

Faculty Publications

Nontuberculous mycobacterial (NTM) infections present a treatment challenge for clinicians and patients. There are limited data about current susceptibility patterns and treatment outcomes in U.S. adults. This was a 10-year, single-center, retrospective, observational cohort study of adults with a positive NTM culture and clinical suspicion of infection between 1 January 2010 and 30 June 2020. The primary objective was to identify predictors for favorable treatment outcomes. Key secondary objectives were characterization of NTM epidemiology, susceptibility profiles, and safety and tolerability of treatment, including the proportion of subjects with an antimicrobial change and the reasons for the change. Of 250 subjects …

Understanding Alcohol Use Discourse And Stigma Patterns In Perinatal Care On Twitter, Fritz Culp, Yuqi Wu, Dezhi Wu, Yang Ren, Phyllis Raynor, Peiyin Hung, Shan Qiao Ph.D., Xiaoming Li Ph.D., Kacey Eichelberger

Faculty Publications

(1) Background: perinatal alcohol use generates a variety of health risks. Social media platforms discuss fetal alcohol spectrum disorder (FASD) and other widespread outcomes, providing personalized user-generated content about the perceptions and behaviors related to alcohol use during pregnancy. Data collected from Twitter underscores various narrative structures and sentiments in tweets that reflect large-scale discourses and foster societal stigmas; (2) Methods: We extracted alcohol-related tweets from May 2019 to October 2021 using an official Twitter search API based on a set of keywords provided by our clinical team. Our exploratory study utilized thematic content analysis and inductive qualitative coding methods …

Accounting For The Growth Of Observation Stays In The Assessment Of Medicare’S Hospital Readmissions Reduction Program, Amber K. Sabbatini, Karen E. Joynt-Maddox, Joshua M. Liao, Anirban Basu, Canada Parrish, William Kreuter, Brad Wright Ph.D.

Faculty Publications

Importance Decreases in 30-day readmissions following the implementation of the Medicare Hospital Readmissions Reduction Program (HRRP) have occurred against the backdrop of increasing hospital observation stay use, yet observation stays are not captured in readmission measures.

Objective To examine whether the HRRP was associated with decreases in 30-day readmissions after accounting for observation stays.

Design, Setting, and Participants This retrospective cohort study included a 20% sample of inpatient admissions and observation stays among Medicare fee-for-service beneficiaries from January 1, 2009, to December 31, 2015. Data analysis was performed from November 2021 to June 2022. A differences-in-differences analysis assessed changes in …