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Articles 2671 - 2700 of 2933

Full-Text Articles in Medicine and Health Sciences

Ohio Academy Of Medical History Annual Meeting Program, March 28, 1992, Ohio Academy Of Medical History Mar 1992

Ohio Academy Of Medical History Annual Meeting Program, March 28, 1992, Ohio Academy Of Medical History

Annual Conference Programs

This one page program is from the annual meeting of the Ohio Academy of Medical History held on March 28, 1992. The program details the events and presentations of the meeting.


Anion Permeation In An Apical Membrane Chloride Channel Of A Secretory Epithelial Cell, Dan R. Halm, Raymond A. Frizzell Mar 1992

Anion Permeation In An Apical Membrane Chloride Channel Of A Secretory Epithelial Cell, Dan R. Halm, Raymond A. Frizzell

Neuroscience, Cell Biology & Physiology Faculty Publications

Single channel currents though apical membrane Cl channels of the secretory epithelial cell line T84 were measured to determine the anionic selectivity and concentration dependence of permeation. The current-voltage relation was rectified with single channel conductance increasing at positive potentials. At 0 mV the single channel conductance was 41 ± 2 pS. Permeability, determined from reversal potentials, was optimal for anions with diameters between 0.4 and 0.5 nm. Anions of larger diameter had low permeability, consistent with a minimum pore diameter of 0.55 nm. Permeability for anions of similar size was largest for those ions with a more symmetrical charge …


Bulletin - Winter, 1992, Civil Aviation Medical Association Jan 1992

Bulletin - Winter, 1992, Civil Aviation Medical Association

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A twelve page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Bulletin - Fall, 1991, Civil Aviation Medical Association Oct 1991

Bulletin - Fall, 1991, Civil Aviation Medical Association

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An eight page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Vital Signs, October 1991, Boonshoft School Of Medicine Oct 1991

Vital Signs, October 1991, Boonshoft School Of Medicine

Vital Signs

A nine page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.


Strain-Specific Neutralizing Determinant In The Transmembrane Protein Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Daniel P. Silva, Fulvia Dimarzo Veronese, Ronald C. Desrosiers Apr 1991

Strain-Specific Neutralizing Determinant In The Transmembrane Protein Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Daniel P. Silva, Fulvia Dimarzo Veronese, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

Monoclonal antibody SF8/5E11, which recognizes the transmembrane protein (TMP) of simian immunodeficiency virus of macaque monkeys (SIVmac), displayed strict strain specificity. It reacted with cloned and uncloned SIVmac251 but not with cloned SIVmac142 and SIVmac239 on immunoblots. This monoclonal antibody neutralized infection by cloned, cell-free SIVmac251 and inhibited formation of syncytia by cloned SIVmac251-infected cells; these activities were specific to cloned SIVmac251 and did not occur with the other viruses. Site-specific mutagenesis was used to show that TMP amino acids 106 to 110 (Asp-Trp-Asn-Asn-Asp) determined the strain specificity of the monoclonal antibody. This strain-specific neutralizing determinant is located within a …


Selection Of Genetic Variants Of Simian Immunodeficiency Virus In Persistently Infected Rhesus Monkeys, Dawn P. Wooley, Ronald C. Desrosiers Apr 1991

Selection Of Genetic Variants Of Simian Immunodeficiency Virus In Persistently Infected Rhesus Monkeys, Dawn P. Wooley, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

Genetic and antigenic variation may be one means by which lentiviruses that cause AIDS avoid elimination by host immune responses. Genetic variation in the envelope gene (env) was studied by comparing the nucleotide sequences of 27 clones obtained from two rhesus monkeys infected with molecularly cloned simian immunodeficiency virus. All 27 clones differed from each other and differed from the input clone in the gp120 (SU) portion of the envelope gene. Nucleotide substitutions were shown to accumulate with time at an average rate of 8.5 per 1,000 per year in SU. Surprisingly, the majority of nucleotide substitutions (81%) resulted in …


Ohio Academy Of Medical History Annual Meeting Program, March 16, 1991, Ohio Academy Of Medical History Mar 1991

Ohio Academy Of Medical History Annual Meeting Program, March 16, 1991, Ohio Academy Of Medical History

Annual Conference Programs

This one page program is from the annual meeting of the Ohio Academy of Medical History held on March 16, 1991. The program details the events and presentations of the meeting.


Sodium Pump And Leaks In Cultured Vascular Endothelial Cells, Norma C. Adragna Dec 1990

Sodium Pump And Leaks In Cultured Vascular Endothelial Cells, Norma C. Adragna

Pharmacology and Toxicology Faculty Publications

No abstract provided.


Vital Signs, December 1990, Boonshoft School Of Medicine Dec 1990

Vital Signs, December 1990, Boonshoft School Of Medicine

Vital Signs

A fifteen page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.


Bulietin - August 1990, Civil Aviation Medical Association Aug 1990

Bulietin - August 1990, Civil Aviation Medical Association

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A four page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Vital Signs, June 1990, Boonshoft School Of Medicine Jun 1990

Vital Signs, June 1990, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.


Bulletin - April, 1990, Civil Aviation Medical Association Apr 1990

Bulletin - April, 1990, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A six page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Ohio Academy Of Medical History Annual Meeting Program, March 10, 1990, Ohio Academy Of Medical History Mar 1990

Ohio Academy Of Medical History Annual Meeting Program, March 10, 1990, Ohio Academy Of Medical History

Annual Conference Programs

This one page program is from the annual meeting of the Ohio Academy of Medical History held on March 10, 1990. The program details the events and presentations of the meeting.


Bulletin - January, 1990, Civil Aviation Medical Association Jan 1990

Bulletin - January, 1990, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A twelve page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Significance Of Premature Stop Codons In Env Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Yathirajulu M. Naidu, Harry W. Kestler Iii, Muthiah D. Daniel, Yen Li, Ronald C. Desrosiers Nov 1989

Significance Of Premature Stop Codons In Env Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Yathirajulu M. Naidu, Harry W. Kestler Iii, Muthiah D. Daniel, Yen Li, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

The location of the translational termination codon for the transmembrane protein (TMP) varies in three infectious molecular clones of simian immunodeficiency virus from macaques (SIVmac). The SIVmac251 and SIVmac142 infectious clones have premature stop signals that differ in location by one codon; transfection of these DNAs into human HUT-78 cells yielded virus with a truncated TMP (28 to 30 kilodaltons [kDa]). The SIVmac239 infectious clone does not have a premature stop codon in its TMP-coding region. Transfection of HUT-78 cells with this clone initially yielded virus with a full-length TMP (41 kDa). …


Vital Signs, September 1989, Boonshoft School Of Medicine Sep 1989

Vital Signs, September 1989, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.


Micronuclear Genome Organization In Euplotes Crassus: A Transposonlike Element Is Removed During Macronuclear Development, Scott Everet Baird, Gina M. Fino, Susan L. Tausta, Lawrence A. Klobutcher Sep 1989

Micronuclear Genome Organization In Euplotes Crassus: A Transposonlike Element Is Removed During Macronuclear Development, Scott Everet Baird, Gina M. Fino, Susan L. Tausta, Lawrence A. Klobutcher

Biological Sciences Faculty Publications

After mating, hypotrichous ciliated protozoa transform a set of their micronuclear chromosomes into thousands of short, linear DNA molecules that form the macronuclear genome. To examine micronuclear genome organization in the hypotrich Euplotes crassus, we have analyzed two cloned segments of micronuclear DNA as well as the macronuclear DNA molecules that are derived from them. E. crassus was found to display a number of features characteristic of other hypotrich genomes, including (i) clustering and close spacing of the precursors of macronuclear DNA molecules, (ii) the frequent occurrence of internal eliminated sequences within macronuclear precursors, (iii) overlapping macronuclear precursors, (iv) lack …


Medical Student, Resident, And Faculty Use Of A Computerized Literature Searching System, Ronald J. Markert, Anthony J. Parisi, H. Verdain Barnes, Steven Cohen, Kim X. Goldenberg, Lawrence E. Mieczkowski, Margaret M. Dunn Apr 1989

Medical Student, Resident, And Faculty Use Of A Computerized Literature Searching System, Ronald J. Markert, Anthony J. Parisi, H. Verdain Barnes, Steven Cohen, Kim X. Goldenberg, Lawrence E. Mieczkowski, Margaret M. Dunn

Department of Surgery Faculty Publications

The experiences of medical students, residents, and faculty with a computerized literature searching system were evaluated. Third-year medical students, internal medicine and family practice residents, and full-time and voluntary faculty at one medical school had the opportunity to use a full-text and bibliographic medical literature retrieval system free of charge for an eleven-month period. Subjects conducted nearly nine thousand literature searches over a period of 942 system hours. Questionnaire data showed that participants could learn to use and would use an electronic information system, felt capable of using the system, utilized the system for a variety of purposes and in …


Bulletin - April, 1989, Civil Aviation Medical Association Apr 1989

Bulletin - April, 1989, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A six page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Vital Signs, April 1989, Boonshoft School Of Medicine Apr 1989

Vital Signs, April 1989, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.


Ohio Academy Of Medical History Annual Meeting Program, March 11, 1989, Ohio Academy Of Medical History Mar 1989

Ohio Academy Of Medical History Annual Meeting Program, March 11, 1989, Ohio Academy Of Medical History

Annual Conference Programs

This one page program is from the annual meeting of the Ohio Academy of Medical History held on March 11, 1989. The program details the events and presentations of the meeting.


Bulletin - February, 1989, Civil Aviation Medical Association Feb 1989

Bulletin - February, 1989, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A six page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Bulletin - January, 1989, Civil Aviation Medical Association Jan 1989

Bulletin - January, 1989, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A four page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Characterization Of Chromosome Fragmentation In Two Protozoans And Identification Of A Candidate Fragmentation Sequence In Euplotes Crassus, Scott Everet Baird, Lawrence A. Klobutcher Jan 1989

Characterization Of Chromosome Fragmentation In Two Protozoans And Identification Of A Candidate Fragmentation Sequence In Euplotes Crassus, Scott Everet Baird, Lawrence A. Klobutcher

Biological Sciences Faculty Publications

Following the sexual cycle, hypotrichous ciliated protozoans fragment a set of their micronuclear chromosomes to generate the thousands of short, linear DNA molecules present in the transcriptionally active macronucleus. We have used a hybrid selection procedure to examine macronuclear DNA molecules for subtelomeric length heterogeneity to determine whether chromosome fragmentation occurs at unique or multiple sites. The results suggest that multiple, but closely spaced, chromosome fragmentation sites are used by Oxytricha nova. In contrast, Euplotes crassus uses unique chromosome fragmentation sites in a reproducible manner to generate the ends of macronuclear DNA molecules. Additional studies compared DNA sequences in …


Aldosterone Stimulates K Secretion Across Mammalian Colon Independent Of Na Absorption, Gerhard Rechkemmer, Dan R. Halm Jan 1989

Aldosterone Stimulates K Secretion Across Mammalian Colon Independent Of Na Absorption, Gerhard Rechkemmer, Dan R. Halm

Neuroscience, Cell Biology & Physiology Faculty Publications

K transport across guinea pig (Cavia porcellus) distal colon was measured in vitro using isotopically determined unidirectional fluxes. Aldosterone stimulated electrogenic Na absorption, as measured by amiloride-sensitive short-circuit current (Isc), and reduced net K absorption from +2.5 ± 0.2 µEq/cm2 per hr to +0.8 ± 0.3 µEq/cm2 per hr (mean ± SEM). Amiloride addition to the mucosal solution did not enhance net K absorption, as expected if inhibiting active Na absorption would reduce active K secretion as in the distal nephron. The amiloride-insensitive Isc was -1.0 ± 0.2 µEq/cm2 per hr (mean ± SEM) …


Passive Cation Transport In Reversibly Sickling Deer Red Blood Cells, Norma C. Adragna, Peter K. Lauf Dec 1988

Passive Cation Transport In Reversibly Sickling Deer Red Blood Cells, Norma C. Adragna, Peter K. Lauf

Pharmacology and Toxicology Faculty Publications

No abstract provided.


Vital Signs, December 1988, Boonshoft School Of Medicine Dec 1988

Vital Signs, December 1988, Boonshoft School Of Medicine

Vital Signs

A sixteen page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.


Bulletin - Autumn, 1988, Civil Aviation Medical Association Oct 1988

Bulletin - Autumn, 1988, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A six page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Bulletin - June, 1988, Civil Aviation Medical Association Jun 1988

Bulletin - June, 1988, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A four page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.