Medicine and Health Sciences Commons^™

Examining Gestational Diabetes Mellitus Educational Resources: Patient And Provider Perspectives, Allison F. Peebles, Morgan E. Cooley, Rose A. Maxwell

Student Scholarship

Objective: To analyze the effectiveness of gestational diabetes mellitus (GDM) education as well as patient and provider confidence in education practices. Study

Design: Women with a diagnosis of GDM who delivered at Miami Valley Hospital were included in the study. Patients were asked to complete a questionnaire to evaluate their knowledge and confidence in managing their GDM. Providers were asked to complete a questionnaire to provide their perspective on patient education related to GDM.

Results: Patients correctly identified 66% of the correct ways that GDM affects maternal health, fetal health, and pregnancy complications. Patients felt empowered by their education and …

Diabetes Link To Social Determinants Of Health, Tyler Schimmoeller

Scholarship in Medicine - All Papers

Objective: The purpose of this paper is to investigate diabetes and how premature death rate; income inequality and social associations relate to diabetes prevalence in the state of Washington in 2020. Methods: I investigated the rate of diabetes change in Washington from 201 to 2020 using a paired t-test. The correlation of diabetes rates and the premature age-adjusted mortality was calculated by county in Washington in 2020 using a Pearson/Spearman correlation. I compared the rate of diabetes in Washington to South Carolina, Ohio, and Louisiana by county in 2020 using an ANOVA with posthoc. Lastly, I used a stepwise linear …

Exosomes From Mirna-126-Modified Endothelial Progenitor Cells Alleviate Brain Injury And Promote Functional Recovery After Stroke, Jinju Wang, Shuzhen Chen, Wenfeng Zhang, Yanfang Chen, Ji Chen Bihl

Pharmacology and Toxicology Faculty Publications

Aims: We previously showed that the protective effects of endothelial progenitor cells (EPCs)-released exosomes (EPC-EXs) on endothelium in diabetes. However, whether EPC-EXs are protective in diabetic ischemic stroke is unknown. Here, we investigated the effects of EPC-EXs on diabetic stroke mice and tested whether miR-126 enriched EPC-EXs (EPC-EXs miR126 ) have enhanced efficacy. Methods: The db/db mice subjected to ischemic stroke were intravenously administrated with EPC-EXs 2 hours after ischemic stroke. The infarct volume, cerebral microvascular density (MVD), cerebral blood flow (CBF), neurological function, angiogenesis and neurogenesis, and levels of cleaved caspase-3, miR-126, and VEGFR2 were measured on day 2 …

The Relationship Between Upstream Variables And Diabetes In Ohio, Brenna Lammers

Scholarship in Medicine - All Papers

Chronic illness is a significant contributor to disease burden in the US. Among these chronic conditions, diabetes is one of the most prevalent. Knowing the relationships between various factors and the prevalence of diabetes would be beneficial to creating targeted approaches to address this major public health problem. Therefore, the objective of this project was to elucidate the relationship between social determinants of health (unemployment, food environment index, and access to exercise opportunities) and access to care variables (ratio of population to primary care physicians and percent uninsured) with prevalence of diabetes by county in Ohio. This was done through …

The Impact Of Food Insecurity On Diabetes Prevalence In The Us: A Look At The Northeast And The Midwest, Richard Mensah

Scholarship in Medicine - All Papers

Diabetes is one of the most common chronic conditions globally. Various risk factors have been found to be associated with the incidence of diabetes. These include genetic predispositions, physical activity and diet. However, less attention has been given to the potential risk of food insecurity to diabetes prevalence. Therefore, the goal of this study was to look at the prevalence of food insecurity and diabetes in New York and Ohio, and try to see if a correlation exists between food insecurity and diabetes prevalence in these states.

In our methods, we used the 2019 data from County Health Rankings (CHR) …

The American Pediatric Type 2 Diabetes Epidemic: Considerations For Targeted Diabetes Prevention Programs, Dolores Dodson

Master of Public Health Program Student Publications

Childhood obesity is an identified risk factor for several long-term health issues such as type 2 diabetes mellitus (T2DM). According to the Centers for Disease Control and Prevention (CDC), diabetes is the seventh leading cause of death within the United States. The CDC has implemented an evidence-based program, The National Diabetes Prevention Program (DPP), to prevent the development of T2DM among individuals with prediabetes. Prediabetes is defined as having elevated glucose levels glycated hemoglobin [A1C] levels between 5.7%-6.5%) that are not elevated enough to meet diabetes diagnosis criteria (A1C levels > 6.5%). The DPP is a lifestyle change program that has …

Diabetic Db/Db Mice Exhibit Central Nervous System And Peripheral Molecular Alterations As Seen In Neurological Disorders., A. Ernst, Ajaykumar Narayan Sharma, Khalid M. Elased, P. C. Guest, H. Rahmoune, S. Bahn

Pharmacology and Toxicology Faculty Publications

The db/db mouse is a widely used preclinical model in diabetes research. Recent studies have shown that these mice also display aspects of psychosis and depression-like behaviors as seen in some psychiatric disorders. Here, we have performed multiplex immunoassay and liquid chromatography mass spectrometry profiling of the plasma and brain samples from db/db and control mice to identify altered pathways, which could be related to these behavioral abnormalities. This is the first study to carry out profiling of the brain proteome in this model. Plasma from the db/db mice had increased levels of leptin and insulin, decreased levels of peptide …

Food Deserts And Their Association With Obesity And Diabetes In Ohio, Alexis Holmes, Detra Thompson

Master of Public Health Program Student Publications

Objective- The purpose of this study was to explore the association of food access, and availability, on prevalence of diabetes and obesity in Ohio census tracts designated as food deserts.

Methods- County and census tract-level data were combined from the USDA Food Environment Atlas and USDA Food Desert Locator respectively. Statistical analysis was conducted using IBM Statistical Package for Social Sciences (SPSS). Non-normally distributed variables were assessed using the Mann-Whitney nonparametric U-test and Spearman’s correlation coefficient. Significance was considered at the p

Results- The mean rate of obesity and diabetes in Ohio in food deserts are 29.5% and 10.7%, when …

Factors That Influence Food Access In The United States: A Snapshot Of Food Access In Ohio And Kentucky, Maimouna Falls

Master of Public Health Program Student Publications

Background: The United States is one the richest countries in the world with a Gross Domestic Product (GDP) per capita of $48,442, yet many communities lack access to affordable nutritious food. Access to food impacts health outcomes such as obesity and diabetes. The purpose of this study was to determine the association between food access and rates of obesity and diabetes in the states of Ohio and Kentucky.

Methods: County level food access data from 120 counties in Kentucky and 88 counties in Ohio were obtained from the USDA website. The dataset included demographic variables and poverty rates. Food access …

The Association Between Neighborhood Walkability, Type 2 Diabetes, And Socioeconomic Status In Residents Of Eight Ohio Counties, Dawn L. Ebron

Master of Public Health Program Student Publications

Objective: Regular physical activity is beneficial in preventing type 2 diabetes. Walking, either for recreation or to travel to a destination, is an inexpensive way to meet physical activity guidelines. Disadvantaged populations with low socioeconomic status (SES) have a higher prevalence of type 2 diabetes and are more likely to live in unwalkable neighborhood. The purpose of this study was to determine the association between SES and neighborhood walkability in eight Ohio counties with highest prevalence of type 2 diabetes in the state.

Methods: Using data from the 2010 Ohio Behavioral Risk Factor Surveillance System (BRFSS) survey and Walk Score …

Diabetes Obesity-Wellness Opportunity Program (Dowop) Evaluation, Francis Banahene

Master of Public Health Program Student Publications

The aim of the study was to evaluate Diabetes Obesity - Wellness Opportunities Program (DOWOP) for overweight and obese adolescents aged eight to 14 years.

The study was conducted over 14 weeks at Victor J. Cassano, Sr. Health Center in Dayton, Ohio. Thirteen weekly nutrition, exercise and cognitive presentations were held. Cooking class was held on week thirteen. Participants completed food and activity diaries. The program sessions focused on healthy eating, increasing physical activity, decreasing sedentary behavior and supporting participants maintain healthy lifestyle.

Nurses recorded BMI and waist circumference at baseline, week 7 and week 14. Program administrators were interviewed …