Medicine and Health Sciences Commons^™

Speech/Language Impairment Or Specific Learning Disability? Examining The Usage Of Educational Categories, Lisa Archibald, Wendy C. Georgan, Tiffany Hogan

Data and Test Instruments

No abstract provided.

Association Between Measures Of Cognitive Function On Physical Function In Novice Users Of A Lower Limb Prosthesis, Humberto Omana, Courtney Frengopoulos, Manuel Montero-Odasso, Michael W. Payne, Ricardo Viana, Susan W. Hunter

Physical Therapy Publications

BACKGROUND: Cognitive impairment is prevalent in people with lower limb amputations (PLLA) and is associated with adverse outcomes, such as falls and worse rehabilitation outcomes. Physical function tests are essential to examine abilities; however, no research in PLLA has clarified the magnitude of cognitive demands amongst available tests in users novice at walking with a prosthesis.

METHODS: People from inpatient prosthetic rehabilitation were recruited. Inclusion criteria were: age ≥ 50 years, unilateral transtibial amputation and able to walk independently. Gait velocity and the L Test under single-task (usual) and dual-task (walking while counting backwards) conditions assessed functional mobility. The Four …

Covid-19 Plasma Proteome Reveals Novel Temporal And Cell-Specific Signatures For Disease Severity And High-Precision Disease Management, Douglas Fraser

Data and Test Instruments

No abstract provided.

Association Between Balance Confidence And Basic Walking Abilities In People With Unilateral Transtibial Lower-Limb Amputations: A Cross-Sectional Study, Humberto Omaña, Courtney Frengopoulos, Manuel Montero-Odasso, Michael W. Payne, Ricardo Viana, Susan W. Hunter

Physical Therapy Publications

INTRODUCTION: Falls are common for people with lower-limb amputations (PLLA). Low balance confidence is also prevalent, is worse in PLLA not reporting walking automaticity, and is known to negatively affect prosthesis use, social engagement, and quality of life. Moreover, walking with a prosthesis requires continuous attention. Low balance confidence may act as a distractor imposing an additional cognitive load on the already cognitively demanding task of walking with a prosthesis.

METHODS: Adults with unilateral, transtibial amputations were recruited. The Activities-specific Balance Confidence (ABC) scale quantified balance confidence. The L Test assessed basic walking abilities under single-task (ST) (usual) and dual-task …

Interrater Reliability Of The Focus-34: Parent-To-Parent And Parent-To-Clinician, Barbara Jane Cunningham, Peter Rosenbaum, Anastasia Nepotiuk, Nancy Thomas-Stonell

PRECISe Preschool Speech and Language Publications

This brief report presents interrater reliability data for the Focus on the Outcomes of Communication Under Six (FOCUS-34) between parents, and between parents and speech-language pathologists (SLPs). Reliability for all three raters combined was good to excellent across three assessments. Reliability for pairs of raters was variable but generally good.

Beyond The Medals: A Cross-Sectional Study Exploring Retired Elite Female Athletes' Health., Jane Thornton, Casey Rosen, Margie Davenport, Margo Lynn Mountjoy, Paul Dorian, Vincent Gouttebarge, Becky Breau, Eva Pila, Kristen Reilly, Jane Yuan, Kelly Mok, Steve Di Ciacca, Mark Speechley, Kay Crossley

Family Medicine Publications

OBJECTIVES: Little is known about the impact of elite sport participation on long-term athlete health. We aimed to: (1) describe musculoskeletal, mental health, reproductive/endocrine and cardiovascular characteristics in retired elite female athletes and compare to the general population and (2) explore athletes' perceptions of their elite sport participation and its impact on health.

METHODS: A 136-item online questionnaire was disseminated to Canadian elite female rowing and rugby athletes >18 years old, >2 years retired from elite competition. Matched general population data were obtained from Statistics Canada when available.

RESULTS: Seventy-four (24% response rate) athletes (average age 45 (±9) years; retired …

Cross-Immunity Against Sars-Cov-2 Variants Of Concern In Naturally Infected Critically Ill Covid-19 Patients, Douglas Fraser

Data and Test Instruments

No abstract provided.

Are Sub-Saharan African National Food And Agriculture Policies Nutrition-Sensitive? A Case Study Of Ethiopia, Ghana, Malawi, Nigeria, And South Africa, Roshaany Asirvatham

Health Studies Publications

Background

In sub-Saharan Africa (SSA), malnutrition coupled with rising rates of undernutrition and the burden of overweight/obesity remains one of the most significant public health challenges facing the region. Nutrition-sensitive agriculture can play an important role in reducing malnutrition by addressing the underlying causes of nutrition outcomes. Therefore, we aim to assess the nutrition-sensitivity of food and agriculture policies in SSA and to provide recommendations for identified policy challenges in implementing nutrition-sensitive agriculture initiatives.

Methods

We assessed past and current national policies relevant to agriculture and nutrition from Ethiopia, Ghana, Malawi, Nigeria, and South Africa. Thirty policies and strategies were …

Ontario Adults’ Mental Health And Wellbeing During The First 16 Months Of The Covid-19 Pandemicno Title, Katie Shillington, Leigh Vanderloo, Shauna Burke, Victor Ng, Patricia Tucker, Jennifer Irwin

Health Studies Publications

This study quantitatively assessed adults’ mental health and overall wellbeing over time during the first 16 months of the pandemic in Ontario, Canada. A total of 2,188 participants participated in the study and completed online questionnaires at three time points (baseline—April–July 2020; time 2—July–August 2020; and time 3—July–August 2021), which included demographic questions, the Mental Health Inventory (MHI), and the Personal Wellbeing Index-Adult (PWI-A). One-way repeated-measures ANOVAs revealed a statistically significant increase over time in participants’ mental health (MHI), as well as a significant decrease in their satisfaction with their standard of living, physical health, mental health, personal relationships, safety, …

Association Between Children’S And Parents’ Physical Activity During The Covid-19 Pandemic: A Cross-Lagged Analysis, Monika Szpunar, Matthew Bourke, Leigh Vanderloo, Brianne Bruijns, Stephanie Truelove, Shauna Burke, Jason Gilliland, Jennifer Irwin, Patricia Tucker

Health Studies Publications

Background: COVID-19 caused closures of movement supporting environments such as gyms and schools in Canada. This study evaluated the association between Ontario parents’ and children’s physical activity levels across time during COVID-19, controlling for variables that were identified as significant predictors of children’s and parents’ physical activity (e.g., children’s age, parents’ employment status). Methods: Parents (n = 243; mean age = 38.8 y) of children aged 12 and under (n = 408; mean age = 6.3 y) living in Ontario, Canada completed 2 online surveys, the first between August and December 2020 and the second between August and December 2021. …

Parents' Attitudes Regarding Their Children's Play During Covid-19: Impact Of Socioeconomic Status And Urbanicity, Leigh Vanderloo, Kendall Saravanamuttoo, Matthew Bourke, Shiran Zhong, Monika Szpunar, Jason Gilliland, Shauna Burke, Jennifer Irwin, Stephanie Truelove, Patricia Tucker

Health Studies Publications

ObjectivesThe COVID-19 pandemic has had a profound impact on the daily routines of parents and children. This study explored the influence of socioeconomic status (SES) and urbanicity on parents' attitudes toward their children's active play opportunities 6 months and 1.5 years into COVID-19.MethodsA sample of 239 Ontario parents of children aged 12 and younger completed two online surveys (August–December 2020; 2021) to assess parents' intentions, beliefs, and comforts concerning their child's eventual return to play, in addition to various sociodemographic and physical activity variables. Descriptive analyses were run as well as an exploratory factor analysis (EFA) was conducted to group …

Assessing The Impact Of Pregnancy And Birth Factors On The Maternal And Infant Microbiota, Kait F. Al, Laura Allen, Samantha Bedell, Jeremy P. Burton, Barbra De Vrijer

Obstetrics & Gynaecology Publications

Background: The microbiota acquired at birth is known to play an intimate role in later life health and disease and has been shown to be affected by the mode of birth. There has been recent interest in microbiota correction by maternal vaginal seeding in Cesarean section-born infants; however, the safety of this practice has been debated. The aim of this study was to assess how other factors, such as timing of sampling, maternal obesity, vaginal Group B Streptococcus colonization (GBS), and antibiotic exposure, affect the maternal and infant microbiota.

Methods: Maternal vaginal and saliva samples were collected at three time …

Usability Evaluation Of A Self-Management Mobile Application For Individuals With A Mild Traumatic Brain Injury, Marquise M Bonn, Laura J. Graham, Stephanie Marrocco, Samantha Jeske, Becky Moran, Dalton L Wolfe

Physical Therapy Publications

OBJECTIVE: Mild traumatic brain injuries (mTBIs) are common and may result in persisting symptoms. Mobile health (mHealth) applications enhance treatment access and rehabilitation. However, there is limited evidence to support mHealth applications for individuals with an mTBI. The primary purpose of this study was to evaluate user experiences and perceptions of the Parkwood Pacing and Planning™ application, an mHealth application developed to help individuals manage their symptoms following an mTBI. The secondary purpose of this study was to identify strategies to improve the application. This study was conducted as part of the development process for this application.

METHODS: A mixed …

Critiquing Representations Of Intellectual Disability In Occupation-Based Literature, Rachel Reparon, Pamela Block, Ann Fudge Schormans, Debbie Laliberte Rudman, Gail Teachman

Occupational Therapy Publications

Background: Within and beyond occupation-based scholarship, concerns abound regarding the pervasiveness of discourses that promote a negative, deficit-based view of intellectual disability and associated consequences for disabled people’s lives. Such representations risk reducing the complexities of human doing and being and can limit the occupational possibilities of this group. Yet, there is a lack of critically reflexive research exploring how disability is discursively constructed in occupation-based literature.

Aims/Objectives: This paper critically analyses representations of intellectual disability within occupation-based literature. It considers the influence of such representations on the occupational possibilities of people labelled intellectually disabled.

Methods: This review employed a …

History Of International Aid, Obidimma Ezezika, Kishif Fatima, Umayangga Yogalingam, Mona Jarrah, Suzanne Sicchia

Health Studies Publications

The following interactive discussion questions are based on a fictional animated storyline developed from Chapter 2 of the third edition of An Introduction to Global Health by Michael Seear and Obidimma Ezezika. The storyline and questions are intended to provide students with the opportunity to understand trends that shaped the modern aid industry, the origins of foreign aid institutions and organizations, and the history that led to current large-scale foreign aid initiatives.

There are questions for each of the five modules of the storyline as well as general reflection questions at the end. To answer the questions associated with the …

An Introduction To The Sustainable Developmental Goals Through The Lens Of Dewroze, Obidimma Ezezika, Kishif Fatima, Umayangga Yogalingam, Mona Jarrah, Suzanne Sicchia

Health Studies Publications

The following interactive discussion questions are based on a fictional animated storyline by Chapter 1 of the third edition of An Introduction to Global Health. The animated storyline and questions are intended to provide students with the opportunity to understand global health, the Sustainable Development Goals (SDGs), and barriers related to the social determinants of health, in the context of a developing country.

Students will be introduced to the fictional village of Dewroze where they will learn how poverty shapes vulnerabilities that lead to health inequities. In this village, students will meet Ada, Ada’s father, Ada’s mother who is pregnant, …

What Are The Barriers And Facilitators To Community Handwashing With Water And Soap? A Systematic Review., Obidimma Ezezika, Jennifer Heng, Kishif Fatima, Ayman Mohamed, Kathryn Barrett

Health Studies Publications

Handwashing with water and soap (HWWS) is an effective method of cleaning and disinfecting the surface of the hands. HWWS is effective in infection control and prevention transmission, such as in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). However, rates of handwashing compliance vary globally. This systematic review aimed to identify the barriers and facilitators to community HWWS globally. We conducted a comprehensive search strategy in OVID Medline, OVID Embase, Web of Science Core Collection, and Scopus using keywords and subject headings related to handwashing. Studies were excluded if they reported hand hygiene among healthcare or food service workers, considered …

The Roles Of Family Physicians During A Pandemic., Maria Mathews, Leslie Meredith, Dana Ryan, Lindsay Hedden, Julia Lukewich, Emily G Marshall, Richard Buote, Lauren Moritz, Sarah Spencer, Shabnam Asghari, Judith B Brown, Thomas R Freeman, Paul S Gill, Rita K Mccracken, Madeleine Mckay, Bridget Ryan, Shannon L Sibbald, Stephen Wetmore, Eric Wong

Health Studies Publications

Family physicians play important roles throughout all stages of a pandemic response; however, actionable descriptions outlining these roles are absent from current pandemic plans. Using a multiple case study design, we conducted a document analysis and interviewed 68 family physicians in four Canadian regions. We identified roles performed by family physicians in five distinct stages of pandemic response: pre-pandemic, phased closure and re-opening, acute care crisis, vaccination, and pandemic recovery. In addition to adopting public health guidance to ensure continued access to primary care services, family physicians were often expected to operationalize public health roles (eg, staffing assessment centres), modulate …

Social And Economic Capital As Effect Modifiers Of The Association Between Psychosocial Stress And Oral Health, Abby L J Hensel, Noha Gomaa

Dentistry Publications

OBJECTIVES: To assess the extent of the association of psychosocial stress with oral health in an Ontario population stratified by age groups, and whether any association is modified by indicators of social and economic capital.

METHODS: We retrieved data of 21,320 Ontario adults, aged 30-74 years old, from the Canadian Community Health Survey (CCHS: 2017-2018), which is a Canada-wide, cross-sectional survey. Using binomial logistic regression models that adjusted for age, sex, education, and country of birth, we examined the association of psychosocial stress (indicated by perceived life stress) with inadequate oral health (indicated as having at least one of the …

Estimation Of Free Water-Corrected Microscopic Fractional Anisotropy., Nico J J Arezza, Tales Santini, Mohammad Omer, Corey A Baron

Medical Biophysics Publications

Water diffusion anisotropy MRI is sensitive to microstructural changes in the brain that are hallmarks of various neurological conditions. However, conventional metrics like fractional anisotropy are confounded by neuron fiber orientation dispersion, and the relatively low resolution of diffusion-weighted MRI gives rise to significant free water partial volume effects in many brain regions that are adjacent to cerebrospinal fluid. Microscopic fractional anisotropy is a recent metric that can report water diffusion anisotropy independent of neuron fiber orientation dispersion but is still susceptible to free water contamination. In this paper, we present a free water elimination (FWE) technique to estimate microscopic …

Dentate Gyrus Integrity Is Necessary For Behavioral Pattern Separation But Not Statistical Learning, Helena Shizhe Wang, R. Shayna Rosenbaum, Stevenson Baker, Claire Lauzon, Laura Batterink, Stefan Köhler

Brain and Mind Institute Researchers' Publications

Pattern separation, the creation of distinct representations of similar inputs, and statistical learning, the rapid extraction of regularities across multiple inputs, have both been linked to hippocampal processing. It has been proposed that there may be functional differentiation within the hippocampus, such that the trisynaptic pathway (entorhinal cortex > dentate gyrus > CA3 > CA1) supports pattern separation, whereas the monosynaptic pathway (entorhinal cortex > CA1) supports statistical learning. To test this hypothesis, we investigated the behavioral expression of these two processes in BL, an individual with highly selective bilateral lesions in the dentate gyrus that presumably disrupts the trisynaptic pathway. We tested pattern …

Increased Top-Down Control Of Emotions During Symptom Provocation Working Memory Tasks Following A Rct Of Alpha-Down Neurofeedback In Ptsd., Saurabh Bhaskar Shaw, Andrew A Nicholson, Tomas Ros, Sherain Harricharan, Braeden Terpou, Maria Densmore, Jean Theberge, Paul Frewen, Ruth A Lanius

Department of Medicine Publications

BACKGROUND: Posttraumatic stress disorder (PTSD) has been found to be associated with emotion under-modulation from the prefrontal cortex and a breakdown of the top-down control of cognition and emotion. Novel adjunct therapies such as neurofeedback (NFB) have been shown to normalize aberrant neural circuits that underlie PTSD psychopathology at rest. However, little evidence exists for NFB-linked neural improvements under emotionally relevant cognitive load. The current study sought to address this gap by examining the effects of alpha-down NFB in the context of an emotional n-back task.

METHODS: We conducted a 20-week double-blind randomized, sham-controlled trial of alpha-down NFB and collected …

How The Body Remembers: Examining The Default Mode And Sensorimotor Networks During Moral Injury Autobiographical Memory Retrieval In Ptsd., Breanne E Kearney, Braeden A Terpou, Maria Densmore, Saurabh B Shaw, Jean Theberge, Rakesh Jetly, Margaret C Mckinnon, Ruth A Lanius

Department of Medicine Publications

Neural representations of sensory percepts and motor responses constitute key elements of autobiographical memory. However, these representations may remain as unintegrated sensory and motor fragments in traumatic memory, thus contributing toward re-experiencing and reliving symptoms in trauma-related conditions such as post-traumatic stress disorder (PTSD). Here, we investigated the sensorimotor network (SMN) and posterior default mode network (pDMN) using a group independent component analysis (ICA) by examining their functional connectivity during a script-driven memory retrieval paradigm of (potentially) morally injurious events in individuals with PTSD and healthy controls. Moral injury (MI), where an individual acts or fails to act in a …

Homeostatic Normalization Of Alpha Brain Rhythms Within The Default-Mode Network And Reduced Symptoms In Post-Traumatic Stress Disorder Following A Randomized Controlled Trial Of Electroencephalogram Neurofeedback., Andrew A Nicholson, Maria Densmore, Paul A Frewen, Richard W J Neufeld, Jean Theberge, Rakesh Jetly, Ruth A Lanius, Tomas Ros

Department of Medicine Publications

Collective research has identified a key electroencephalogram signature in patients with post-traumatic stress disorder, consisting of abnormally reduced alpha (8-12 Hz) rhythms. We conducted a 20-session, double-blind, randomized controlled trial of alpha desynchronizing neurofeedback in patients with post-traumatic stress disorder over 20 weeks. Our objective was to provide mechanistic evidence underlying potential clinical improvements by examining changes in aberrant post-traumatic stress disorder brain rhythms (namely, alpha oscillations) as a function of neurofeedback treatment. We randomly assigned participants with a primary diagnosis of post-traumatic stress disorder (

A Simple Perfused Cadaver Model For Damage Control Vascular Surgery Training, Shane A. Smith, Vivian C. Mcalister O.C.

Surgery Publications

No abstract provided.

Brain-Based Arterial Pulse Pressure Threshold For Death Determination: A Systematic Review, Saptharishi Lalgudi Ganesan

Data and Test Instruments

No abstract provided.

Nontherapeutic Research With Imminently Dying And Recently Deceased Study Populations: Addressing Practical And Ethical Challenges, Saptharishi Lalgudi Ganesan

Data and Test Instruments

No abstract provided.

An App-Based Ecological Momentary Assessment Of Undergraduate Mental Health During The Covid-19 Pandemic In Canada (Smart Healthy Campus Version 2.0): Longitudinal Study, Kelly Anderson, Chris Brogly, Daniel Lizotte, Marc Mitchell, Mark Speechley, Arlene Macdougall, Erin Huner, Michael Bauer

Data and Test Instruments

No abstract provided.

Comparing Youth With Vs Without Outpatient Mental Health Services On Subsequent Acute Mental Health Care Visits, Kelly Anderson, Jordan Edwards, Li Wang, Anne Fuller, Katholiki Georgiades

Data and Test Instruments

No abstract provided.

Neighbourhood-Level Social Capital, Marginalisation, And The Incidence Of Schizophrenia And Schizoaffective Disorder In Toronto, Canada: A Retrospective Population-Based Cohort Study, Kelly Anderson, Martin Rotenberg, Kwame Mckenzie, Andrew Tuck

Data and Test Instruments

No abstract provided.