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Virginia Commonwealth University

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Articles 31 - 60 of 4969

Full-Text Articles in Medicine and Health Sciences

Modeling The Immune Response To Immunotherapy And Triple Negative Breast Cancer In Mice, Dayton J. Syme, Angelica Davenport, Yun Lu, Anna G. Sorace, Nicholas G. Cogan May 2023

Modeling The Immune Response To Immunotherapy And Triple Negative Breast Cancer In Mice, Dayton J. Syme, Angelica Davenport, Yun Lu, Anna G. Sorace, Nicholas G. Cogan

Biology and Medicine Through Mathematics Conference

No abstract provided.


Coffee Break And Breakout Discussions, Coffee May 2023

Coffee Break And Breakout Discussions, Coffee

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Hiv With Partnership Models, Kathleen Hoffman May 2023

Modeling Hiv With Partnership Models, Kathleen Hoffman

Biology and Medicine Through Mathematics Conference

No abstract provided.


Incorporating Interventions To An Extended Seird Model With Vaccination: Application To Covid-19 In Qatar, Elizabeth B. Amona May 2023

Incorporating Interventions To An Extended Seird Model With Vaccination: Application To Covid-19 In Qatar, Elizabeth B. Amona

Biology and Medicine Through Mathematics Conference

No abstract provided.


Generalized Differential Equation Models For Disease Interventions: A Novel Approach For Predicting Sexually Transmitted Disease Outbreaks, Scott Greenhalgh May 2023

Generalized Differential Equation Models For Disease Interventions: A Novel Approach For Predicting Sexually Transmitted Disease Outbreaks, Scott Greenhalgh

Biology and Medicine Through Mathematics Conference

No abstract provided.


Relative Efficacy Of Resource Constrained Forward And Backward Contact Tracing In An Open Population, Nicholas Roberts May 2023

Relative Efficacy Of Resource Constrained Forward And Backward Contact Tracing In An Open Population, Nicholas Roberts

Biology and Medicine Through Mathematics Conference

No abstract provided.


Exploration Of Differential Equation Models For Phage-Bacteria Population Dynamics, John Lawrence D. Palacios, Rebecca Segal May 2023

Exploration Of Differential Equation Models For Phage-Bacteria Population Dynamics, John Lawrence D. Palacios, Rebecca Segal

Biology and Medicine Through Mathematics Conference

No abstract provided.


Utilizing Optimization Techniques To Build A Patient-Specific 1d Arterial Network For Single Ventricle Patients, Alyssa M. Lapole May 2023

Utilizing Optimization Techniques To Build A Patient-Specific 1d Arterial Network For Single Ventricle Patients, Alyssa M. Lapole

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Honeymoon And Divorce Effects In Wolbachia Control Trials Of Dengue, Casey P. O'Brien May 2023

Modeling Honeymoon And Divorce Effects In Wolbachia Control Trials Of Dengue, Casey P. O'Brien

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling The Dynamics Of Alcohol-Marijuana Co-Abuse In Virginia, Ana L. Vivas-Barber, James Tipton, Sujan Pant, Anne Fernando May 2023

Modeling The Dynamics Of Alcohol-Marijuana Co-Abuse In Virginia, Ana L. Vivas-Barber, James Tipton, Sujan Pant, Anne Fernando

Biology and Medicine Through Mathematics Conference

No abstract provided.


Identifiability Analysis Applied To Rhizbium-Legume Symbiosis Model, Meghan Peltier May 2023

Identifiability Analysis Applied To Rhizbium-Legume Symbiosis Model, Meghan Peltier

Biology and Medicine Through Mathematics Conference

No abstract provided.


Poster Session, 1. Poster May 2023

Poster Session, 1. Poster

Biology and Medicine Through Mathematics Conference

No abstract provided.


Thoracoabdominal Asynchrony In A Virtual Preterm Infant: Computational Modeling And Analysis, Richard R. Foster, Laura Ellwein Fix, Bradford Smith May 2023

Thoracoabdominal Asynchrony In A Virtual Preterm Infant: Computational Modeling And Analysis, Richard R. Foster, Laura Ellwein Fix, Bradford Smith

Biology and Medicine Through Mathematics Conference

No abstract provided.


Exploring The Dynamics Of Bacterial Populations In The Gut Microbiota, Shaikh Obaidullah May 2023

Exploring The Dynamics Of Bacterial Populations In The Gut Microbiota, Shaikh Obaidullah

Biology and Medicine Through Mathematics Conference

No abstract provided.


Chemoattractant Distribution In Complex Geometry Impacts The Trajectory Of Clustered Cell Migration, Naghmeh Akhavan May 2023

Chemoattractant Distribution In Complex Geometry Impacts The Trajectory Of Clustered Cell Migration, Naghmeh Akhavan

Biology and Medicine Through Mathematics Conference

No abstract provided.


Undergraduate Research In Mathematical Biology Needs A Cure, Olcay Akman May 2023

Undergraduate Research In Mathematical Biology Needs A Cure, Olcay Akman

Biology and Medicine Through Mathematics Conference

No abstract provided.


Pde Model For Protocell Evolution And The Origin Of Chromosomes Via Multilevel Selection, Daniel B. Cooney, Fernando W. Rossine, Dylan H. Morris, Simon A. Levin May 2023

Pde Model For Protocell Evolution And The Origin Of Chromosomes Via Multilevel Selection, Daniel B. Cooney, Fernando W. Rossine, Dylan H. Morris, Simon A. Levin

Biology and Medicine Through Mathematics Conference

No abstract provided.


Lunch-Provided, Lunch May 2023

Lunch-Provided, Lunch

Biology and Medicine Through Mathematics Conference

No abstract provided.


Helices In Fluids And Their Applications, Eva M. Strawbridge May 2023

Helices In Fluids And Their Applications, Eva M. Strawbridge

Biology and Medicine Through Mathematics Conference

No abstract provided.


Pk/Pd Modeling Coupled With A Phenotype-Structured Population Model For Reducing Drug Resistance, Lifeng Han May 2023

Pk/Pd Modeling Coupled With A Phenotype-Structured Population Model For Reducing Drug Resistance, Lifeng Han

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Long-Wave Model For Film Flow Inside A Tube With Slip, Mark S. Schwitzerlett, Ihsan Topaloglu, H. Reed Ogrosky May 2023

A Long-Wave Model For Film Flow Inside A Tube With Slip, Mark S. Schwitzerlett, Ihsan Topaloglu, H. Reed Ogrosky

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Epithelial-Mesenchymal Transition In A 3d Multicellular Model Of Tgf-Β1 Signaling, Kristin Kim, Chris Lemmon May 2023

Modeling Epithelial-Mesenchymal Transition In A 3d Multicellular Model Of Tgf-Β1 Signaling, Kristin Kim, Chris Lemmon

Biology and Medicine Through Mathematics Conference

No abstract provided.


Networking Coffee Break, Coffee May 2023

Networking Coffee Break, Coffee

Biology and Medicine Through Mathematics Conference

No abstract provided.


Leader, Follower, And Cheater: Modeling Collective Cancer Invasion, Yi Jiang May 2023

Leader, Follower, And Cheater: Modeling Collective Cancer Invasion, Yi Jiang

Biology and Medicine Through Mathematics Conference

No abstract provided.


Opening Remarks, Rebecca A. Segal, Angela M. Reynolds May 2023

Opening Remarks, Rebecca A. Segal, Angela M. Reynolds

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Multifaceted Approach Using Implementation Science Methods To Increase Chg Bathing Compliance And Reduce Central Line Associated Blood Stream Infections On A Non-Icu Unit, Emily E. Warwick Jan 2023

A Multifaceted Approach Using Implementation Science Methods To Increase Chg Bathing Compliance And Reduce Central Line Associated Blood Stream Infections On A Non-Icu Unit, Emily E. Warwick

VCU Health Nursing

BACKGROUND or RATIONALE:

The Acute Care Surgery unit (ACS) is a General and Progressive level of care post-operative unit at VCU Health system. Between quarter four 2021 and quarter one of 2023, five Central line associated blood stream infections (CLABSIs) occurred. NDNQI data revealed ACS had a higher CLABSI rate per 1,000 patient days than the national average of other similar type units in other magnet hospitals.

STATEMENT OF THE PROBLEM:

A GAP analysis revealed ACS did not achieve the 80% CHG compliance goal set by VCU Health’s Infection Prevention Department in all six quarters that these five CLABSIs occurred. …


Ur-Ine Good Hands In The Neuroscience Intensive Care Unit, Molly Lehatto, Courtney Hastings, Monika Mehlbrech, Christina Szabo Jan 2023

Ur-Ine Good Hands In The Neuroscience Intensive Care Unit, Molly Lehatto, Courtney Hastings, Monika Mehlbrech, Christina Szabo

VCU Health Nursing

Purpose:

The purpose of this performance improvement project was to decrease the harm to patients related to catheter associated urinary tract infections (CAUTIs) in the Neuroscience Intensive Care Unit (NSICU). Historically, the NSICU had the highest CAUTI rates in our organization with as many as 6 CAUTIs per calendar year quarter. A core group of nurses partnered with providers, hospital infection preventionists and nursing leaders to improve practices for placing, removing, and managing urinary catheters and to implement guidelines for urine testing stewardship.

Description:

Significance: In 2020, the NSICU had 12 CAUTIs, the highest number of CAUTIs in the entire …


Infiltrating Cd8+ T Cells Exacerbate Alzheimer’S Disease Pathology In A 3d Human Neuroimmune Axis Model, Jefin Jose, Devam Purohit Jan 2023

Infiltrating Cd8+ T Cells Exacerbate Alzheimer’S Disease Pathology In A 3d Human Neuroimmune Axis Model, Jefin Jose, Devam Purohit

VCU's Medical Journal Club: The Work of Future Health Professionals

In this study, Jorfi et al. employed a neuroimmune axis model containing neurons, astrocytes, and microglia to examine the role of immune cells in Alzheimer's disease. Jorfi et al. found that T cells selectively infiltrated the BRAIN compartment of the neuroimmune axis model as compared to B cells and monocytes. Jorfi et al. further found that CD8+ T cells demonstrated heightened cytotoxicity in the Alzheimer's disease brain, illuminating the role of immune cells in neurodegeneration. Upon further examination, the CXCR3-CXCL10 signaling pathway was found to have an important role in inflammation.


A Genome-Wide In Vivo Crispr Screen Identifies Essential Regulators Of T Cell Migration To The Cns In A Multiple Sclerosis Model, Jefin Jose Jan 2023

A Genome-Wide In Vivo Crispr Screen Identifies Essential Regulators Of T Cell Migration To The Cns In A Multiple Sclerosis Model, Jefin Jose

VCU's Medical Journal Club: The Work of Future Health Professionals

Kendirli et al. (2023) used a CRISPR screen to determine the proteins involved in T cell migration into the CNS in multiple sclerosis. Overall, eighteen facilitators and five brakes to T cell infiltration into the CNS were identified. Kendirli et al. specifically identified ITGA4, FERMT3, and HSP90B1 to make up the adhesion module, CXCR3, GNAI2, and TBX21 to make up the chemotaxis module, and GRK2 and S1PR2 to make up the egress module. This study demonstrated the ability of a CRISPR screen to identify elements in a disease process and thus identify targets for future multiple sclerosis therapies.


A Learning Health System For Radiation Oncology, Rishabh Kapoor Jan 2023

A Learning Health System For Radiation Oncology, Rishabh Kapoor

Theses and Dissertations

The proposed research aims to address the challenges faced by clinical data science researchers in radiation oncology accessing, integrating, and analyzing heterogeneous data from various sources. The research presents a scalable intelligent infrastructure, called the Health Information Gateway and Exchange (HINGE), which captures and structures data from multiple sources into a knowledge base with semantically interlinked entities. This infrastructure enables researchers to mine novel associations and gather relevant knowledge for personalized clinical outcomes.

The dissertation discusses the design framework and implementation of HINGE, which abstracts structured data from treatment planning systems, treatment management systems, and electronic health records. It utilizes …