Medicine and Health Sciences Commons^™

The Gay Nineties: Oscar Wilde Reconsidered, Frederick J. Spencer

MCV/Q, Medical College of Virginia Quarterly

Sex and hypocrisy have always been bedmates, but never more than in Victorian England. In the “Gay Nineties” promiscuity was widely accepted in all social classes, although the aristocracy hid its lust behind a strict code of propriety. Country house parties catered to infidelities with the approval of the Prince of Wales, himself a notorious womanizer.

Recent Advances In Cancer Chemotherapy, Robert B. Diasio

MCV/Q, Medical College of Virginia Quarterly

The present state of cancer chemotherapy can be reviewed in light of selected basic principles with an acknowledgement of the role of established chemotherapeutic agents. Four chemotherapeutic agents recently approved for clinical use and their impact when used in combination regimens should be examined. Several important concepts influencing chemotherapy in the 1980s include the use of chemotherapy in the adjuvant setting, the use of hormonal receptor data in planning therapy, and the use of in vitro tests on tumor specimens to predict tumor sensitivity to cancer chemotherapy drugs (prior to administration of these potentially toxic drugs to a particular patient). …

Changing Concepts Of Cancer Biology, Diagnosis And Treatment, Robert N. Taub

MCV/Q, Medical College of Virginia Quarterly

Cancer is the number two killer in the United State and will probably account for some 400,000 deaths in 1982. The lung has now achieved the dubious distinction of being the most common site of cancer in men and causes the most deaths. Cancer of the colon and rectum is the second most common cancer in both males and females combined, whereas carcinoma of the breast and uterus predominate in women.

Breast Cancer: An Update, Wade K. Smith

MCV/Q, Medical College of Virginia Quarterly

Breast cancer comprises approximately 13.9% of all cases of malignancy in both sexes and 19% in women, in whom it is the commonest form of cancer. The American Cancer Society estimates that 110,000 women developed breast cancer in 1981, and some 37,100 deaths from the disease occurred. The five-year survival rate has been improving over the past 40 years as shown in Table 1, but patients remain in risk of recurrence indefinitely and survival for ten years is generally accepted as the minimal time period necessary to establish the validity of new therapies.

Tapping The Tube, Sara Kaltreider

MCV/Q, Medical College of Virginia Quarterly

Before percussion and mediate auscultation were discovered, methods of physical examination – in particular chest examination – were limited. Only observation was used with any regularity. From the time of Hippocrates, palpation and direct auscultation had been used sporadically to detect heartbeats but had not proved to be of practical value because clinicopathological correlation had not yet been established. At last, when a new method called percussion was conceived by Auenbrugger in 1761, it was ignored for almost forty years. Not until the French School evolved did percussion become established, largely through Corvisart, Napoleon’s private physician. Coincident with the revival …

Volume Sixteen Author Index

MCV/Q, Medical College of Virginia Quarterly

Author Index for MCV/Q, Medical College of Virginia Quarterly, 1981, Volume Sixteen.

A Cyproheptadine-Reversible Defect In Acth Control Persisting After Removal Of The Pituitary Tumor In Cushing's Disease, Harvey V. Lankford , M.D., H. St. George Tucker , M.D., William G. Blackard , M.D.

Internal Medicine Publications

Abstract

We studied two phases of cortisol feedback suppression of ACTH in nine patients who had had adrenalectomy for Cushing's disease. Four had been treated by adrenalectomy alone and presumably had ACTH-secreting pituitary tumors. Five others were studied two or more years after transsphenoidal removal of an ACTH-secreting microadenoma. In both groups, cortisol-ACTH feedback during the first 30 minutes of cortisol infusion was abnormal; plasma ACTH fell only 2.7±2.6 per cent (mean ±S.E.), as compared with 28.0±10.1 per cent in five hypoadrenal controls (P<0.01). The fall in ACTH during the second phase of cortisol infusion was similar in the patients and the controls. Cyproheptadine corrected the feedback abnormality occurring during the first phase in both groups of patients with Cushing's disease; ACTH fell by 24.4±4.8 per cent (P<0.005). Persistence of a cortisol-ACTH feedback abnormality after removal of the pituitary tumor in Cushing's disease, as well as the correction by cyproheptadine, suggests that higher centers have a role in the pathophysiology of Cushing's disease. (N Engl J Med. 1981; 305:1244–8.)

Traumatic Acute Subdural Hematoma — Major Mortality Reduction In Comatose Patients Treated Within Four Hours, John M. Seelig , M.D., Donald P. Becker , M.D., J. Douglas Miller , M.D., Ph.D., F.R.C.S., F.A.C.S., Richard P. Greenberg , M.D., Ph.D., John D. Ward , M.D., Sung C. Choi , Ph.D

Biostatistics Publications

To discover which factors contributed to recovery after surgical intracranial decompression, we reviewed the records of 82 consecutive comatose patients with traumatic acute subdural hematoma (ASDH) who were treated in a single center under a uniform protocol. The delay from injury to operation was the factor of greatest therapeutic importance. Patients who underwent surgery within the first four hours had a 30 per cent mortality rate, as compared with 90 per cent in those who had surgery after four hours (P

Virginia Dental Journal (Vol. 58, No. 4, 1981)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 58, No. 5, 1981)

Virginia Dental Journal

No abstract provided.

Volume Sixteen Subject Index

MCV/Q, Medical College of Virginia Quarterly

Subject Index for MCV/Q, Medical College of Virginia Quarterly, 1981, Volume Sixteen.

Colonial Cultivation And Concoctions, Sara Jones Gomberg

MCV/Q, Medical College of Virginia Quarterly

Have you ever wondered how to increase the value of your property? One way would be to include a well-cultivated herb garden, that is if you were a seventeenth-century colonist. Not only were the herbs much sought after for their culinary uses but also for their medicinal properties. Today’s medical library may not include a collection of botany books, yet botanical knowledge was a large part of early medical training and the mainstay of the “cavalier concoctions” used by colonists for medical treatment.

[Note From The Editor], Frederick J. Spencer

MCV/Q, Medical College of Virginia Quarterly

The MCV Quarterly ceases publication with this issue. No journal of this type can be self-supporting and we bow to the inevitable reality of inflation. The idea of the Quarterly came from Sami Said. Almost single handed he cajoled and coerced the Dean of the School of Medicine into finding the money for publication. Throughout its existence MCV/Q has remained true to its stated purpose of disseminating “scientific information from all sources”, resisting several attempts to convert it into a “house journal” or popular newssheet. In essence, it has been the printed pivot of continuing education in the medical school.

Recent Advances In Gastorintestinal Cancer, Galen L. Wampler

MCV/Q, Medical College of Virginia Quarterly

Colorectal carcinoma accounts for the majority of all gastrointestinal cancers and is the second leading site of cancer, excluding skin cancers, in overall incidence in the United States. Cancer of the stomach, although decreasing in frequency is still an important cause of morbidity and mortality. Unfortunately, data from large numbers of patients such as can be found in Cancer Patient Survival Report No. 5 show only very modest increases in survival for patients with these diseases in recent years.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 15 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

The Relationship Between A Patient's Stress Level During Hospitalization And His Perception Of His Significant Family Member's Role In Providing Support, Susan Carey Williams Johnson

Theses and Dissertations

A descriptive study was undertaken to investigate the relationship between a patient's stress level during hospitalization and his perception of his significant family member's role providing support. The following subproblems were also addressed:

(1) What types of activities, presently or potentially performed by a significant family member, does the patient perceive as supportive?

(2) What types of nursing activities, as perceived by the patient, are being done to encourage/discourage performance of family support activities?

(3) What other factors does the patient perceive as encouraging/discouraging performance of these family role-related activities?

The Hospital Stress Rating Scale (Volicer and Bohannon, 1975) was …

The Relationship Between Self-Concept And Locus Of Control In Physically Abused Women, Betsy Wright Shires

Theses and Dissertations

History can provide some clues concerning the physical abuse of women by men. Beginning in biblical times, women were viewed as the property of men (Steinmetz, 1977). Until 1824 by law, a man was allowed to strike his wife if provoked (Bell, 1977). Under the law, some states still grant "spouse immunity" in cases of assault and battery, where married couples are involved.The focus of this research was to examine the problem of wife abuse through the perspective of social learning theory. Using Roy's theory of adaptation (Roy, 1976), the investigator also examined the area of self-concept as it related …

Virginia Dental Journal (Vol. 58, No. 6, 1981)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 58, No. 1, 1981)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 58, No. 3, 1981)

Virginia Dental Journal

No abstract provided.

Medicine In Retrospect

MCV/Q, Medical College of Virginia Quarterly

The following is a transcript of an informal talk by Drs. Kinloch Nelson and Charles M. Caravati, presented in 1974 to the School of Medicine of the Medical College of Virginia, Health Sciences Division of Virginia Commonwealth University, Richmond, Virginia.

Synthesis And Biological Evaluation Of Sparsomycin Analogues, Scherer Preston Sanders

Theses and Dissertations

In 1962, Owen, Dietz, and Camiener reported the isolation of a new antitumor antibiotic from the culture filtrate of Streptomyces sparsogenes. The structure of the crystalline antibiotic, named sparsomycin, remained elusive until 1970, when Wiley and MacKellar reported results of spectroscopic and degradation studies which elucidated the structure. In addition to the molecular structure, investigators have examined the mechanism of action, toxicity, and related analogues, striving to establish sparsomycin or a synthetic analogue's usefulness as an effective chemotherapeutic agent.

The initial pharmacological evaluation of sparsomycin revealed it possessed activity against KB human epidermoid carcinoma cells, a variety of gram-negative and …

Virginia Dental Journal (Vol. 58, No. 2, 1981)

Virginia Dental Journal

No abstract provided.

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1981, Volume Sixteen, Numbers Three and Four.

Temperature Recordings In Neonates, Linda Marie Hestvik

Theses and Dissertations

Summary

The purposes of this ex post facto research study were to answer the following questions:

1. What is the length of time required for glass thermometers to register the temperature in neonates at the rectal and axillary sites?

2. Do significant differences exist between simultaneous axillary and rectal temperature recordings in neonates?

3. What is the relationship between axillary and rectal temperature recordings at specified time intervals in neonates?

A sample of 30, full-term neonates was obtained from the Newborn Nursery of a large teaching hospital in the Middle Atlantic region. All participants were over 24 hours of age …

An Evaluation Of A Coronary Education Program, Anne Broaddus Sydnor

Theses and Dissertations

This study was conducted to evaluate a Coronary Educational Program at a 350 bed community suburban hospital. The five year old program has never been evaluated. The evaluation was limited to one product of the program, the change in patient knowledge relative to their disease. Subjects also completed a subjective evaluation of the program, including the content areas, teaching methods, and competence of the instructors.

Twelve subjects participated during the 2% month study. They consisted of 10 males and 2 females; 11 Whites and 1 Black. The age range was 53 to 76 years, with a mean of 63.9 years. …

Self-Perceived Needs Of Adult Males And Their Significant Others Following Colostomy For Colo-Rectal Cancer, Derry Ware

Theses and Dissertations

In spite of continuing advances in diagnostic methods, surgical and medical management, and psychological care, cancer remains the second leading cause of death among adults in the United States (American Cancer Society, 1980), and it continues to engender feelings of futility in its victims and the general population as well. Between 1970 and 1980 more than 6.5 million new cases of cancer were diagnosed, and more than 10 million people were under medical treatment for the disease. There are over 3 million Americans presently alive who have a history of cancer (American Cancer Society, 1980). Approximately 15 percent of all …

The Relationship Between Type A Coronary-Prone Behavior Pattern, Achievement, And Life Satisfaction, Larraine A. Felland

Theses and Dissertations

This study examined the relationship between Type A coronary-prone behavior pattern, academic achievement and life satisfaction. The subjects were 87 undergraduates selected for their extreme scores on the Jenkins Activity Survey, Form T. There were 41 Type As and 46 Type Bs. Along with the Jenkins Activity Survey, Form T the participants were administered a life satisfaction survey similar to Soper's (1979) and their official academic gradepoint average was obtained from the Academic Records office. A point-biserial correlation indicated that there was a significant (p

The various relationships and their possible explanations and indications were discussed in depth. Significance of …

An Investigation Of Central Nervous System Conduction Properties In Diabetes Mellitus Using Brainstem Auditory And Somatosensory Evoked Potentials, Randy L. Anderson

Theses and Dissertations

In this study brainstem auditory evoked potentials (BAEPs), median nerve conduction velocities (CV) and early somatosensory evoked potentials ( SEPs), were employed as indices of neural conduction properties in a group of young insulin dependent diabetics (five males and five females) and a group of nondiabetic controls (five males and five females). The median nerve CV was determined from 64 summated nerve responses recorded at the elbow. The nerve was stimulated at the wrist using 0.2 msec square wave electrical pulses. The SEP was recorded from scalp electrodes using the same median nerve stimulation technique as for the CV measure. …

An Analysis Of The Effect Of Immediate Corrective Feedback Administered As A Study Aid To Undergraduate Medical Technology Students, Constance Anne Bak

Theses and Dissertations

Twenty-six undergraduate medical technology students at Virginia Commonwealth University were provided with a Hemestasis Study Guide to use during this unit and in preparing for an exam in this area. The study guide contained fifty objective-related questions in multiple-choice format. Answers were printed in latent image and included positive reinforcement for correct selections and remediation for incorrect ones. Thus the student received immediate feedback concerning his response to each question.

An examination grade continuum was plotted for this class utilizing all exam grades in the Hematology course. A similar continuum was plotted for each of the three previous classes. (These …