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Cancer; Chemotherapy; Doxorubicin; Bleomycin; Tamoxifen Citrate; Adjuvant Chemotherapy; Receptor Status; Drug Response; Drug Effects
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Recent Advances In Cancer Chemotherapy, Robert B. Diasio
Recent Advances In Cancer Chemotherapy, Robert B. Diasio
MCV/Q, Medical College of Virginia Quarterly
The present state of cancer chemotherapy can be reviewed in light of selected basic principles with an acknowledgement of the role of established chemotherapeutic agents. Four chemotherapeutic agents recently approved for clinical use and their impact when used in combination regimens should be examined. Several important concepts influencing chemotherapy in the 1980s include the use of chemotherapy in the adjuvant setting, the use of hormonal receptor data in planning therapy, and the use of in vitro tests on tumor specimens to predict tumor sensitivity to cancer chemotherapy drugs (prior to administration of these potentially toxic drugs to a particular patient). …