Medicine and Health Sciences Commons^™

Identification Of Lipid Species: Potential Biomarkers For Early Detection Of Hepatocellular Carcinoma, Kit Yee Leung, Kaylee Freitas

Undergraduate Research Symposium Posters

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is associated with cirrhosis. Poor survival rate of HCC is due to diagnosis of HCC at late stage.

Is There An App For That? Social Support, Depression, And Anxiety Among Users Of A Digital Mental Health App, Bryce V. Brown, Teresa J. Walker, Christine Guardian, Matthew Schurr

Undergraduate Research Symposium Posters

Perceived social support has been associated with mental health. Social distancing guidelines due to COVID-19 heavily shifted social engagement to digital formats. It is important to understand the role of digital mental health interventions in mental health outcomes.

Who Is Gonna See The Shrink? Anxiety And Depression's Relationship To Openness And Willingness To Engage In Weekly Psychotherapy, Bryce V. Brown, Teresa J. Walker, Christine Guardian, Matthew Schurr

Undergraduate Research Symposium Posters

Digital mental health interventions may offer an alternative to in-person psychotherapy. It is important to understand attitudes about traditional in-person psychotherapy among app users to contextualize treatment seeking and better understand treatment options.

The Relationship Between Misophonia Sensitivity And Musicality, Mae Ling Catayong, Sarah Uganiza, William Smithers, Aileen Corral, Sivan Barashy, Solena Mednicoff, Destiny Gonzales

Undergraduate Research Symposium Posters

Misophonia is a condition characterized by negative emotional reactions to certain everyday sounds. Musicality involves Active Musical Engagement (AE), Self-reported Perceptual Abilities (PA), Musical Training (MT), Self-reported Singing Abilities (SA), Sophisticated Emotional Engagement with Music (EM), and General musical sophistication (GM). Numerous active musicians have self-reported having misophonia, while anecdotal reports have shown that music can help treat misophonia symptoms.

Misophonia Sensitivity Is Related To Enhanced Responsiveness To Misophonia, Asmr And Musical Frisson, Alexis Rice, Kiara O'Keefe, Kacey Chang, Sivan Barashy, Solena Mednicoff, Destiny Gonzales

Undergraduate Research Symposium Posters

Misophonia: a condition in which specific everyday sounds (e.g., chewing, breathing) trigger an atypical, negative emotional response.

ASMR: a sensory phenomenon triggered by stimuli that induce a state of relaxation, positive feelings, and tinging sensations that spread from the head to the rest of the body.

Musical frisson: typically characterized by positive affect and strong physiological reactions, such as shivering, goosebumps, and teary-eyes in response to highly pleasurable music.

You Never Walk Alone: How Bts Supports Army Mental Health And Well-Being, Melissa Le

Undergraduate Research Symposium Posters

BTS is a seven-membered South Korean boyband with a fandom named "ARMY." Music is generally associated with increased mental health, but not all types of music genres have been studied yet. With the current rise of Korean popular music (K-pop), it is important to understand what makes this genre popular and why fans claim it has improved their mental health. As BTS is currently the most popular K-pop group globally, they provide a unique look at how their music can help fans with depression and anxiety.

Climate Change Hope Scale: Factor Analysis In An Adult Sample, Gemma Ortega, Steven J. Glover, Jesse Tabaczynksi, Orei Z. Odents

Undergraduate Research Symposium Posters

Willpower - how much individuals believe that set goals can be met. Waypower - the extent to which individuals can think of strategies for accomplishing those goals.

The Climate Change Hope Scale (CCHS; Li & Monroe, 2017) was designed to measure three aspects of hope: 1. Personal sphere willpower and waypower (WP) 2. Collective sphere willpower and waypower (CW) 3. Lack of willpower and waypower (LW).

A three-factor model fits the CCHS among adolescents. The purpose of our study was to determine if the three-factor model fits the CCHS in adults.

Assessing Psychological Impact Of Covid-19 Among Parents Of Children Returning To K-12 Schools: A U.S. Based Cross-Sectional Survey, Kavita Batra, Jennifer R. Pharr, Emylia Terry, Brian Labus

School of Medicine Faculty Research

Background and Purpose: While impacts of the pandemic on family well-being have been documented in the literature, little is known about the psychological challenges faced by children and their parents as schools reopen after mandated closures. Therefore, the purpose of this study was to determine if sending children back to in-person school impacts the mental health of parents and the perceived mental health of their children. Methods: This cross-sectional descriptive study recruited a nationally representative, non-probability sample of parents or guardians (n = 2100) of children attending grades K-12 in the United States (U.S.) through a 58-item web-based survey. The …

Use Of Wastewater Surveillance For Early Detection Of Alpha And Epsilon Sars-Cov-2 Variants Of Concern And Estimation Of Overall Covid-19 Infection Burden, Van Vo, Richard L. Tillett, Katerina Papp, Shirley Shen, Richard Gu, Andrew Gorzalski, Danielle Siao, Rayma Markland, Ching-Lan Chang, Hayley Baker, Jingchun Chen, Martin Schiller, Walter Q. Betancourt, Erin Buttery, Mark Pandori, Michael A. Picker, Daniel Gerrity, Edwin C. Oh

Nevada Institute of Personalized Medicine Faculty Research

A decline in diagnostic testing for SARS-CoV-2 is expected to delay the tracking of COVID-19 variants of concern and interest in the United States. We hypothesize that wastewater surveillance programs provide an effective alternative for detecting emerging variants and assessing COVID-19 incidence, particularly when clinical surveillance is limited. Here, we analyzed SARS-CoV-2 RNA in wastewater from eight locations across Southern Nevada between March 2020 and April 2021. Trends in SARS-CoV-2 RNA concentrations (ranging from 4.3 log10 gc/L to 8.7 log10 gc/L) matched trends in confirmed COVID-19 incidence, but wastewater surveillance also highlighted several limitations with the clinical data. Amplicon-based whole …

Mental Disorder Symptoms During The Covid-19 Pandemic In Latin America – A Systematic Review And Meta-Analysis, Stephen X. Zhang, Kavita Batra, Wen Xu, Tao Liu, Rebecca Kechen Dong, Allen Yin, Andrew Yilong Delios, Bryan Z. Chen, Richard Z. Chen, Saylor Miller, Xue Wan, Wenping Ye, Jiyao Chen

School of Medicine Faculty Research

Aims There is a lack of evidence related to the prevalence of mental health symptoms as well as their heterogeneities during the coronavirus disease 2019 (COVID-19) pandemic in Latin America, a large area spanning the equator. The current study aims to provide meta-analytical evidence on mental health symptoms during COVID-19 among frontline healthcare workers, general healthcare workers, the general population and university students in Latin America. Methods Bibliographical databases, such as PubMed, Embase, Web of Science, PsycINFO and medRxiv, were systematically searched to identify pertinent studies up to August 13, 2021. Two coders performed the screening using predefined eligibility criteria. …

Youth Mental Health In The Mountain West, Kristian Thymianos, Olivia K. Cheche, Kelliann Beavers, Katie M. Gilbertson, Caitlin J. Saladino, William E. Brown Jr.

Health

This fact sheet explores youth mental health metrics of Mountain West states from the Hopeful Futures Campaign’s 2022 report, America’s School Mental Health Report Card. This study provides state snapshots on school mental health policies and workforce availability for all 50 states and the District of Columbia. The Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah are considered here.

Restoring Wholeness To Psychiatry: Models Of Understanding, Gregory Brown, Lisa Durette, Timothy Ebright, Katie Cho

Psychiatry & Behavioral Health Faculty Research

Psychiatric practice is at a critical juncture in its evolution. Its identified model for understanding the complexity of individuals and their conditions has been the biopsycho-social-spiritual model since it was first proposed nearly half a century ago. In practice, this construct is being challenged by a biomedical model which asserts all psychiatric conditions can be reduced to either neurotransmitter or gene-based causation. We explore how models are used in science to approximate larger reality, with a focus on Systems Theory, which is the philosophical foundation for the bio-psycho-social-spiritual model to describe why this model is necessarily more complete than the …

Exploratory Analysis Of The Associations Between Neonicotinoids And Measures Of Adiposity Among Us Adults: Nhanes 2015–2016, Amruta M. Godbole, Sheniz Moonie, Courtney Coughenour, Cai Zhang, Aimin Chen, Ann M. Vuong

Environmental & Global Health Faculty Research

Background: Toxicology studies suggest that neonicotinoids may be associated with adiposity development via thyroid hormone disruption and increased oxidative stress. Prior epidemiological studies report mixed results for the association between neonicotinoids and adiposity measures.

Objective: To examine the association between detectable concentrations of parent neonicotinoids (imidacloprid, acetamiprid, clothianidin) and neonicotinoid metabolites (5-hydroxy-imidacloprid, N-desmethyl-acetamiprid) with adiposity measures among US adults, and whether sex modifies the associations for neonicotinoid metabolites with adiposity.

Methods: National Health and Nutrition Examination Survey (NHANES) 2015–2016 data was utilized to estimate covariate-adjusted associations between detectable neonicotinoids and fat mass index (FMI), lean mass index (LMI), waist …

Profit Or Purpose: What Increases Medical Doctors’ Job Satisfaction?, Young Kyun Chang, Won-Yong Oh, Sanghee Han

Management, Entrepreneurship and Technology Faculty Research

This study integrates two competing views to examine whether medical doctors are satisfied with their jobs when they perceive their hospitals as being oriented toward profit (i.e., rational choice theory) or purpose (i.e., public service motivation). Using a sample of 127 doctors from 70 hospitals, this study tests these competing views. The results show that doctors who perceive their hospitals as purpose-driven are likely to experience job satisfaction, and this pattern still holds even if they also perceive their hospitals to be emphasizing profits. However, only the purpose-driven orientation results in job satisfaction via a sense of meaningfulness. Thus, this …

Biomechanical Evaluation Over Level Ground Walking Of User-Specific Prosthetic Feet Designed Using The Lower Leg Trajectory Error Framework, Victor Prost, W. Brett Johnson, Jenny A. Kent, Matthew J. Major, Amos G. Winter V.

Physical Therapy Faculty Research

The walking pattern and comfort of a person with lower limb amputation are determined by the prosthetic foot’s diverse set of mechanical characteristics. However, most design methodologies are iterative and focus on individual parameters, preventing a holistic design of prosthetic feet for a user’s body size and walking preferences. Here we refined and evaluated the lower leg trajectory error (LLTE) framework, a novel quantitative and predictive design methodology that optimizes the mechanical function of a user’s prosthesis to encourage gait dynamics that match their body size and desired walking pattern. Five people with unilateral below-knee amputation walked over-ground at self-selected …

Depression And Factors Impacting Quality Of Life Among Adults With Asthma Presence In Nevada, Elizabeth D. Kahane, Lung-Chang Chien, Brian Labus, Dharini M. Bhammar, Jocy-Anna Chevalier, Sheniz Moonie

Epidemiology & Biostatistics Faculty Research

Background: Asthma, a chronic, non-communicable disease has been shown to negatively affect mental health and quality of life among adults. Annually approximately 8% of adult Nevadans report current asthma symptoms and 12.6% report having a lifetime diagnosis. The purpose of this study was to evaluate the association between asthma and depression and explore quality of life factors affecting adult Nevadans with asthma. Methods: Using behavioral risk factor surveillance system (BRFSS) data, this study evaluated the association between self-reported asthma and depression in Nevada using weighted multiple logistic regression. BRFSS asthma call-back survey (ACBS) data were used to determine the frequency …

Introspective Meditation Before Seeking Pleasurable Activities As A Stress Reduction Tool Among College Students: A Multi-Theory Model-Based Pilot Study, Manoj Sharma, Amar Kanekar, Kavita Batra, Traci Hayes, Ram Lakhan

Social and Behavioral Health Faculty Research

In the realm of behavioral interventions, a combined approach of yoga and a cognitive-behavioral strategy in the form of introspective meditation (manan-dhyana) may offer benefits as a stress management tool. This pilot study focuses on introspective meditation performed before seeking pleasurable activities, which is a self-reflection about whether to pursue a goal that will bring sensory pleasure in life. A non-probability sample of college students was recruited from a mid-sized Southern University of the United States using a 52-items web-based survey built in Qualtrics. Univariate, bivariate, and multivariate statistics were used to analyze data. Of total 65 students, only 21.5% …

Fear Of Falling Avoidance Behavior Assessment And Intervention In Parkinson’S Disease: A Scoping Review, John V. Rider, Jason K. Longhurst, Nirmala Lekhak, Daniel L. Young, Merrill R. Landers

Nursing Faculty Research

Falling and fear of falling (FOF) are significant concerns for people with Parkinson’s disease (PD). FOF can lead to activity avoidance behavior, a risk factor for increased falls and further functional decline. The significant implications of fear of falling avoidance behavior (FFAB) among PD warrant a literature review. The objective of this review was to explore existing literature on FFAB and identify what is known about this phenomenon in people with PD. This scoping review considered studies including adults 18 years and older diagnosed with PD experiencing FFAB. Using Joanna Briggs Institute methodology and the PRISMA extension for scoping reviews, …

Knowledge Or Awareness Of Non-Communicable Diseases And Their Associated Risk Factors Among University Students In Fiji: A Cross-Sectional Study, Awadhesh Kumar Shirotriya, Kavita Batra

School of Medicine Faculty Research

Introduction: Chronic diseases (aka Non-communicable diseases, NCDs) contribute to the global burden of morbidity and mortality, with a significant share of premature deaths among low-and middle-income countries (LMICs), including Fiji. The early exposure to the risk factors of NCDs affects the entire life course; knowledge or awareness of adolescents towards NCDs and associated risk factors is critical for health promotion. This study aims to investigate the knowledge or awareness level of chronic conditions and their risk factors among Fijian students. Methods: In this cross-sectional study, a sample of 338 university students was recruited using the paper as well as web-based …

Trends In Scientific Output On The Lesbian, Gay, Bisexual, And Transgender (Lgbt) Community Research: A Bibliometric Analysis Of The Literature, David An, Kavita Batra

School of Medicine Faculty Research

Introduction: Lesbian, Gay, Bisexual, and Transgender (LGBT) represent a diverse group with special needs due to the unusual developmental experiences and social inequalities. This paper aims to explore and outline a future research direction in LGBT issues through tracing our historical understanding of this population from an aspect of scientific research. Methods: LGBT-related peer-reviewed documents were retrieved from the PubMed database and the study period was set from the inception to 2021. Python-based methods were then performed to analyze the publication metadata and extract the most prominent research topics based on the abstract contents. Key points covered in the study …

Spatial Deconcentration Of Tourism Concentrations: A Visitors’ Galaxy Impact Model Of The Covid-19 Crisis, Jaewon Lim, Karima Kourtit, Peter Nijkamp, Christopher Stream

Public Policy and Leadership Faculty Research

This paper analyzes the impact of COVID-19 on mass tourism concentrations, such as Las Vegas. It argues that health risks and perceptions may induce a more deconcentrated pattern of mass tourism, with more geographical dispersion to rural and natural areas. The analytical framework is modeled and applied to extensive data on Las Vegas tourism. The proposition on deconcentrated tourism concentrations is confirmed. Pre-pandemic outer-inner city complementary relations between “Outdoor Activities” in 11 surrounding national parks and the “Gaming Industry” in Las Vegas have transformed into outer-inner city substitution relations in the COVID-19 pandemic. This represents the evolving deconcentration of tourism …

Gingival Transcriptome Of Innate Antimicrobial Factors And The Oral Microbiome With Aging And Periodontitis, Jeffrey L. Ebersole, Sreenatha Kirakodu, Linh Nguyen, Octavio A. Gonzalez

Dental Medicine Faculty Research

The epithelial barrier at mucosal sites comprises an important mechanical protective feature of innate immunity, and is intimately involved in communicating signals of infection/tissue damage to inflammatory and immune cells in these local environments. A wide array of antimicrobial factors (AMF) exist at mucosal sites and in secretions that contribute to this innate immunity. A non-human primate model of ligature-induced periodontitis was used to explore characteristics of the antimicrobial factor transcriptome (n = 114 genes) of gingival biopsies in health, initiation and progression of periodontal lesions, and in samples with clinical resolution. Age effects and relationship of AMF to the …

A Qualitative Analysis Of The Impact Of Electronic Health Records (Ehr) On Healthcare Quality And Safety: Clinicians’ Lived Experiences, Soumya Upadhyay, Han-Fen Hu

Healthcare Administration and Policy Faculty Research

Purpose: There have been mixed findings of clinicians’ perceptions of Electronic Health Record (EHR). This study aims to explore the lived experiences of clinicians, to assess the role of EHR in improving the quality and safety of healthcare.

Basic Procedures: A qualitative study design was used. We collected the opinions from different groups of clinicians (physicians, hospitalists, nurse practitioners, nurses, and patient safety officers) using semi-structured interviews. Organizations represented were trauma hospitals, academic medical centers, medical clinics, home health centers, and small hospitals.

Main findings: Our study found clinicians’ ambivalent assessments toward EHR, which confirms extant literature. …

Evaluating Long-Term Outcomes Of A High School-Based Impaired And Distracted Driving Prevention Program, Lindsay Buczek, Laura K. Gryder, Samantha Slinkard-Barnum, Kavita Batra, Cassandra Trummel, Allison G. Mcnickle, Douglas R. Fraser, Deborah A. Kuhls, Paul J. Chestovich

School of Medicine Faculty Research

Motor vehicle crashes are one of the leading causes of death among teenagers. Many of these deaths are due to preventable causes, including impaired and distracted driving. You Drink, You Drive, You Lose (YDYDYL) is a prevention program to educate high school students about the consequences of impaired and distracted driving. YDYDYL was conducted at a public high school in Southern Nevada in March 2020. A secondary data analysis was conducted to compare knowledge and attitudes of previous participants with first-time participants. Independent-samples-t test and χ2 test/Fisher’s exact test with post-contingency analysis were used to compare pre-event responses between students …

Cellular Dna Effects Of Radiation And Cancer Risk Assessment In Cells With Mitochondrial Defects, J. Chen, D. M. Sridharan, C. L. Cross, J. M. Pluth

Epidemiology & Biostatistics Faculty Research

Mitochondria play a key role in mediating non-targeted effects (NTE) post-radiation exposure. Mitochondrial DNA (mtDNA), due to its less efficient repair as compared to nuclear DNA, is more severely affected by radiation exposure and mutations in essential mtDNA genes can further exacerbate oxidative stress. Our objective was to evaluate the impact of mitochondrial defects on radiation-induced DDR and genomic instability, biomarkers that can foreshadow cancer development. To better understand this relationship, we used commercially available lymphoblastoid cell lines containing characterized mitochondrial mutations and studied the kinetics of DNA damage and relative telomere length (RTL) changes over time post 0.5 Gy …

Association Between Diagnosed Anxiety And Depression And Exposure To Life Stressors During The Covid-19 Pandemic, Emily Hallgren Phd, Don E. Willis Phd, Brett Rowland Ma, James P. Selig Phd, Pearl A. Mcelfish Phd

Journal of Health Disparities Research and Practice

Research suggests that mental health disorders heighten the risk of exposure to life stressors. Drawing on a sample of 754 adults from a survey distributed at six primary care clinics, we examine whether adults who reported ever being diagnosed with depression or anxiety were more likely to experience an employment disruption, a housing disruption, and/or report more COVID-19-related stressors during the COVID-19 pandemic. Individuals who reported ever being diagnosed with depression reported a greater burden (B=.75) of COVID-19-related stressors. Those who reported ever being diagnosed with anxiety had higher odds of experiencing an employment disruption (OR=1.90) and a housing disruption …

Social Support Needs Of Minority Breast Cancer Patients: Significance Of Racial Homogeneity And Kin Composition Of Social Networks, Ganga Vijayasiri, Garth H. Rauscher, Ifeanyi Beverly Chukwudozie, Richard T. Campbell, Richard Warnecke

Journal of Health Disparities Research and Practice

Social support from family and friends assists breast cancer patients navigate a life crisis, but more needs to be understood about specific social network characteristics that can benefit breast cancer patients. To address this need, the primary aim of this study was to identify social network factors that facilitate or reduce social support. Given racially patterned gaps in social support among breast cancer patients, a secondary goal was to identify network characteristics that are linked to gaps in support. We examined these research questions using data from a sample of 915 breast cancer patients (NHWhite=373; NHBlack=377; Hispanic=165) and 4,021 of …

Representation Of Racial/ Ethnic Minority Individuals In The Leadership Of Major Medical Journals, Ashlin Rakhra, Gbenga Ogedegbe, Olajide Williams, Deborah Onakomaiya, Bruce Ovbiagele

Journal of Health Disparities Research and Practice

Medical journals play an important role in achieving health equity by diversifying their leadership, but there is a dearth of published data on how they are faring. The objective of this study was to assess the proportions of the underrepresented in medicine (UIM) racial/ ethnic minorities in medical journal leadership. We pre-selected 6 prominent general medicine journals, 9 prominent specialty journals, and 5 “control” journals (covering public health, health equity, and bench research), assembled names of all editors/ editorial board members listed on the website-based journal mastheads and used major public internet search engines to obtain information about sex, race, …

The Role Of Socioeconomic Status, Race, And Gender In Patient-Reported Outcomes Following Total Hip Arthroplasty, Allyn M. Bove, James Porter, Aatif Sayeed, Clair Smith, Brian A. Klatt

Journal of Health Disparities Research and Practice

Background

Disparities in total joint arthroplasty are well-documented. However, much of the research regarding disparities in vulnerable populations receiving total hip arthroplasty (THA) have focused on short-term outcomes. The purpose of this study was to examine the effects of race, gender, and socioeconomic status (SES) on patient-reported outcomes six months following THA.

Methods

Electronic health record data were retrospectively analyzed for 269 individuals who underwent THA at a large urban hospital from 2013-16. Data retrieved included patient demographics, baseline health information, data regarding hospital length of stay when undergoing THA, post-operative complications, and patient-reported function, measured by the Harris Hip …

Civic Engagement As A Pathway To Meaningful Medical Student Engagement On The Social Determinants Of Health, Alexander Reardon, Jennie Deblanc, Alister Martin

Journal of Health Disparities Research and Practice

The social determinants of health have gained increasing prominence in medical education, but medical students and professionals alike are under-prepared to address those determinants. There is a growing body of evidence that voting and other forms of civic engagement affect the health of patients and communities. Registering patients in healthcare settings offers students and professionals an opportunity to impact their patients’ health beyond the clinical encounter. Medical students are particularly well suited to this work for a variety of reasons, including increasingly positive attitudes toward this kind of advocacy, increasing diversity in the medical student body, and lighter clinical and …