Medicine and Health Sciences Commons^™

National Cancer Centers And Cancer Rates In Nevada, 2017-2021, Yashesvi Sharma, Ivan Sun, Taylor Volk, Caitlin J. Saladino, William E. Brown Jr., Fatma Nasoz

Health

This fact sheet presents data from the National Institutes of Health including the National Cancer Institute’s (NCI) “State Cancer Profiles” report and includes age-adjusted cancer incidence rates by race/ethnicity in Nevada, between 2017 and 2021. The fact sheet also shows data from the 2024 National Cancer Institute’s “NCI-Designated Cancer Centers” map, listing NCI-Designated Cancer Centers by state, and the distance to the nearest NCI-Designated Cancer Centers from the Las Vegas metro and Reno metro.

Trends And Financial Burden Of Gastrointestinal Stromal Tumors In The United States: A Comprehensive Analysis Of United States Hospitalizations, Sneh Sonaiya, Raj Patel, Charmy Parikh, Dushyant Dahiya, Karan Yagnik, Nicholas Alonso Barnechea Alvarado, Chun-Han Lo, Kenneth Chow, Abbas Ali Hussain, Anushri Parikh, Pranav Patel, Babu P. Mohan

Department of Internal Medicine Faculty Research

Background: Gastrointestinal stromal tumors (GISTs) are associated with a substantial economic burden to the healthcare system despite their relatively low incidence and prevalence compared to other more common malignancies. This study aimed to evaluate trends in GIST-related hospitalizations, inpatient mortality, and the financial burden of GISTs in the United States. Methods: The National Inpatient Sample (NIS) database from 2016 to 2020 was used to identify adult hospitalizations (age > 18 years) with a primary diagnosis of GIST. A multivariate logistic regression along with Chi-square and t-tests was performed using SAS 9.4 software to analyze inpatient GIST-associated mortality, inflation-adjusted total hospital charge …

Arrhythmogenic Right Ventricular Cardiomyopathy: A Comprehensive Review, Taha Shaikh, Darren Nguyen, Jasmine Dugal, Michael Dicaro, Brianna Yee, Nazanin Houshmand, Kachon Lei, Ali Namazi

Department of Internal Medicine Faculty Research

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by structural abnormalities, arrhythmias, and a spectrum of genetic and clinical manifestations. Clinically, ARVC is structurally distinguished by right ventricular dilation due to increased adiposity and fibrosis in the ventricular walls, and it manifests as cardiac arrhythmias ranging from non-sustained ventricular tachycardia to sudden cardiac death. Its prevalence has been estimated to range from 1 in every 1000 to 5000 people, with its large range being attributed to the variability in genetic penetrance from asymptomatic to significant burden. It is even suggested that the prevalence is underestimated, as the presence of genotypic mutations …

Atherosclerosis: A Comprehensive Review Of Molecular Factors And Mechanisms, Vasiliki Tasouli-Drakou, Ian Ogurek, Taha Shaikh, Marc Ringor, Michael V. Dicaro, Kachon Lei

Department of Internal Medicine Faculty Research

Atherosclerosis, a condition characterized by the accumulation of lipids and a culprit behind cardiovascular events, has long been studied. However, in recent years, there has been an increase in interest in its initiation, with researchers shifting focus from traditional pathways involving the vascular infiltration of oxidized lipids and towards the novel presence of chronic inflammatory pathways. The accumulation of pro-inflammatory cytokines, in combination with the activation of transcription factors, creates a positive feedback loop that drives the creation and progression of atherosclerosis. From the upregulation of the nod-like receptor protein 3 (NLRP3) inflammasome and the Notch and Wnt pathways to …

Six-Month Follow-Up Comparing Ait And Eft In The Reduction Of Negative Emotions Associated With A Past Memory, Gregory Brown, Kavita Batra, Emily Dorin, Andrew Han, Arianna Palermini, Robert Sottile, Sherine Khanbijian

Psychiatry & Behavioral Health Faculty Research

The field of Energy Psychology [EP] has amassed hundreds published research studies over its thirty year history which includes both systematic review and meta-analysis level data. These have consistently demonstrated significant effect sizes equivalent to EMDR and trauma based CBT (Church et al., 2022; Feinstein, 2021). Energy Psychology Techniques typically include an energetic component, an emotional component, a somatic component, focus upon a specific memory, which lead to automatic secondary cognitive shifts. Memory Reconsolidation may be a primary psycho-biological explanation for effectiveness. Emotional Freedom Technique [EFT] is the most studied EP technique to date, and considered an evidenced based treatment …

Recent Advances In Cardiac Resynchronization Therapy: Current Treatment And Future Direction, Arasalan Siddiqui, Vasiliki Tasouli-Drakou, Marc Ringor, Micael V. Dicaro, Brianna Yee, Kachon Lei, Tahir Tak

Department of Internal Medicine Faculty Research

Cardiac Resynchronization Therapy (CRT) has been established as a major component of heart failure management, resulting in a significant reduction in patient morbidity and death for patients with increased QRS duration, low left ventricular ejection fraction (LVEF), and high risk of arrhythmias. The ability to synchronize both ventricles, lower heart failure hospitalizations, and optimize clinical outcomes are some of the attractive characteristics of biventricular pacing, or CRT. However, the high rate of CRT non-responders has led to the development of new modalities including leadless CRT pacemakers (CRT-P) and devices focused on conduction system pacing (CSP). This comprehensive review aims to …

Cultural Capital Skill Development In Undergraduate Kinesiology Curriculum, Jenica Alvarez, Sabrina R. Fordham, Elizabeth M. Harrison, Blake Podsen, Jason C. Casey, Rich Pruett

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 2, 2025. Specialization within Kinesiology and related fields over the past 20 years has led to the prioritization of technical skill development. This specialization leaves limited availability of resources for the development of Cultural Capital (CC) skills in undergraduate kinesiology and kinesiology-related curricula. The purpose of this study was to examine how seven Experiential Learning Activities (ELAs) influence CC skill development in an undergraduate kinesiology practicum course. An interpretive qualitative action research design was applied to investigate five senior undergraduate kinesiology students’ experiences. The study concluded: (a) six of …

Metabolic Effects Of R-1,3-Butanediol (Ketone-Iq) During Aerobic And Anaerobic Exercise Bouts, Mathew C. Soto, Andrew J. Jakiel, Latt Mansor, Jenica D. Alvarez, Ashley M. Bruce, Blake Podsen, Sabrina R. Fordham, Parker N. Hyde

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 1, 2025. BACKGROUND: Current evidence demonstrates the efficacy of low carbohydrate/high fat ketogenic diets as it related to exercise. Exogenous ketone supplements have made it possible to ingest ketone molecules, elevating blood b-hydroxybutyrate (BHB) despite consuming carbohydrates (CHO). The purpose of this investigation was to determine both metabolic and performance effects of R-1,3-butanediol (BDO). METHODS: A randomized repeated measures placebo-controlled design was used to compare BDO and placebo (PLA). Each phase of testing utilized two primary testing days: 1) a dose exposure day designed to determine blood metabolite changes …

Social Jetlag Alters Markers Of Exercise-Induced Mitochondrial Adaptations In The Heart, Michael B. Dial, Elias M. Malek, Austin R. Cooper, Greco A. Neblina, Nikoleta I. Vasileva, Graham Mcginnis

Kinesiology and Nutrition Sciences Faculty Research

Social jetlag (SJL) represents the behavioral misalignment of sleep and wake times on work days and free days, and potently disrupts the circadian rhythm. SJL affects up to 70% of the population worldwide and is associated with increased risk for many cardiometabolic diseases. Animal models of acute SJL have shown disruption in locomotor activity and expression of clock genes in select tissues, its impact on the heart remains unclear. The purpose of this study was to investigate the effects of prolonged SJL (6 weeks), on activity rhythms, and the impact on exercise-induced adaptations in the heart. Male mice (n …

Achilles Tendon Morphology Adaptations In Chronic Post-Stroke Hemiparesis: A Comparative Analysis With Neurologically Intact Controls, Jing Nong Liang, Greg Bashford, Kornelia Kulig, Kai-Yu Ho

Physical Therapy Faculty Research

Introduction: In individuals with chronic post-stroke hemiparesis, slow walking speed is a significant concern related to inadequate propulsion of the paretic limb. However, an overlooked factor is this population's altered morphology of the Achilles tendon, which may compromise the propulsive forces by the paretic limb. This study aimed to explore changes in Achilles tendon morphology, including gross thickness and intra-tendinous collagen fiber bundle organization, following stroke-induced brain lesions.

Methods: Fifteen individuals with chronic post-stroke hemiparesis (at least 6 months post-stroke) and 19 neurologically intact controls participated. Ultrasound imaging was used to evaluate Achilles tendon thickness and collagen organization in the …

Hypnosis: An Evidenced Based Treatment, Gregory P. Brown

Psychiatry & Behavioral Health Faculty Research

Review of meta analyses and systemic review level studies of hypnosis in the treatment of anxiety, burnout, and depression.

Six-Month Follow-Up Comparing Ait And Eft In The Reduction Of Negative Emotions Associated With A Past Memory, Gregory Brown, Kavita Batra, Emily Dorin, Andrew Han, Arianna Palermini, Robert Sottile, Sherine Khanbijian

Psychiatry & Behavioral Health Faculty Research

Statistics have shown that about sixty percent of individuals with psychiatric illness do not respond adequately to standard treatments, yet only 1% of research studies are focused on developing new therapeutic strategies for these patients (McIntyre et al., 2023). This study investigated the long-term efficacy of Advanced Integrative Therapy (AIT) as compared to Emotional Freedom Techniques (EFT), specifically evaluating the durability of the resolution of emotional distress tied to a single memory six months post-treatment. The study began with 72 participants: and 51 completed a follow-up survey, resulting in a response rate of 70.8%. The sample was predominantly female (65%), …

Programmatic Accreditation: Implementation Strategies For College Kinesiology Program Directors, Kworweinski Lafontant

Topics in Exercise Science and Kinesiology

Programmatic accreditation within Kinesiology sub-disciplines, such as physical therapy and sports medicine, have typically been required at the graduate level. Within the coming decade, major certifications for exercise physiology (ACSM-EP) and strength & conditioning (CSCS) will institute programmatic accreditation requirements at the undergraduate level. This article takes a narrative review approach at examining ways that programmatic accreditation at the undergraduate level may impact incoming undergraduate students, such as necessitating earlier specialization and limiting the ability for late-stage career changes. To mitigate these impacts, college kinesiology program directors may benefit from considering the perspectives of students as they work to meet …

Game On! A Comparative Analysis Of External Load In Division Iii Soccer Players Across Gender And Position, Bianca J. De Lucia, Daniel M. Smith, Ashima Fillbach, Mary K. Feit

Topics in Exercise Science and Kinesiology

Global positioning systems have been used increasingly in sports science due to their ability to quantify external loads of athletes during competitions and practices. Limited research has examined gender differences in external load throughout a collegiate soccer season. PURPOSE: The aim of this study was to compare game workloads across collegiate men (MSOC) and women (WSOC) soccer players. Division III MSOC and WSOC players wore GPS devices during games throughout a 15-week season. METHODS: Metrics analyzed from GPS data were: total distance (TD), sprint distance (SD), number of deceleration efforts (decel) (>-3 m/s²), number of acceleration efforts (accel) ( …

The Relationship Between International Tennis Association Rankings And Total Athleticism Score In Collegiate Athletes, Ryne Yamashiro, Paulette Yamada, Trevor Short

Topics in Exercise Science and Kinesiology

Training tennis athletes for peak athletic performance may translate to enhanced on-court performance, resulting in higher rankings. However, the specific trainable tennis attributes that account for the variance in International Tennis Association (ITA) remain elusive. ITA Rankings are calculated based on how a collegiate tennis athlete performs whereby their rankings will change based on wins or losses and scores against their opponents ITA Ranking. A lower ITA Ranking (closer to 1) indicates a higher ranked tennis player. Holistic athletic profiling can be performed by assessing multiple key performance indicators, with the total athleticism score (TAS) being utilized to …

Does Physician-Hospital Vertical Integration Affect Hospital Output?, Soumya Upadhyay, Neeraj Bhandari

Healthcare Administration and Policy Faculty Research

Background: Physician-hospital vertical integration is gaining steam but it is unclear how they affect hospital output.

Objective: To examine the direct impact of vertical integration on hospital output.

Design: A pooled design with 6-year data using linear regressions was used. Then, panel data design with hospital fixed effects was used.

Methods: We linked American Hospital Association data (2016-2021) with AHRQ Comparative Health System Performance Initiative’s Compendium (2018, 2020, 2021; 34 987 hospital-year observations) to develop new measures of vertical integration and assess its relationship with several measures of hospital output including annualized total admissions, total number of inpatients days, …

Physiology And Genomics At The Bottom Of The World: Genome To Phenome, Amy Christine Klink

UNLV Theses, Dissertations, Professional Papers, and Capstones

Mammals are exposed to a suite of physiological challenges based on the environment in which they inhabit. Animal individuals can overcome challenges associated with the dynamic nature of their habitat through variation in phenotypic traits. The plasticity of a phenotype relies on an individual’s genome and the transcription factors that act on regulatory elements. Species living in Antarctica display physiological specializations to withstand harsh conditions, such as severe cold temperatures, shifts in available ice habitat, and annual fluctuations in daylight. To explore the connections between an individual’s genome and its phenotype, we investigated two physiologies of the Antarctic Weddell seal …

How Culture Impacts Mental Health Help-Seeking Behaviors In College-Aged Chinese Americans, Hui Ching Chan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Adolescents are the most vulnerable to mental health issues in the United States, however, they are the least likely to receive relevant professional services. Particularly, young Chinese American adults who are influenced by traditional Chinese culture retain a higher reluctance to mental health-related help-seeking behaviors.

Chinese American culture is co-constructed with families through parents’ worldviews, parenting styles, socio-economic statuses, and English proficiency. Several studies also suggest that mothers and fathers in Chinese American families play distinct roles in shaping youngsters’ perceptions of mental health awareness. As a result, the culture perceived from families has a significant impact on young Chinese …

The Effects Of First Responder Stress & Trauma On Spouses And Romantic Partners, Eden Thiess

UNLV Theses, Dissertations, Professional Papers, and Capstones

First responder jobs pose unique difficulties due to the sheer number of traumatic events that they witness and personally experience. Research has demonstrated some effects of stress and trauma on family relationships, but the literature lacks an understanding of the ways that first responder trauma and stress affects their marriages and romantic relationships. The current study’s purpose was to investigate the experiences of first responder spouses and partners within the Las Vegas area in regards to stress, trauma, and relationship dynamics as influenced by the first responder role. In this study, 11 participants who were in a marriage or romantic …

The Effects Of A Healthcare Simulation Escape Room On Clinical Judgment: A Randomized Controlled Trial, Jennifer Peltier

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: The predominant pedagogy of traditional lecture-based learning should include meaningful active content to foster clinical judgment, engagement, and knowledge retention. Innovative active learning strategies must be tested to understand if they can better facilitate nursing learners’ readiness for practice.

Aims: This research study investigated the impact of a healthcare simulation escape room as an innovative platform on individual and team clinical judgment to determine whether this active learning strategy can benefit nursing learners’ preparedness and increase clinical judgment.

Method: A randomized, double-blinded, waitlist control design was used to examine the effect of a healthcare simulation escape room on clinical …

Alteration Of Peripheral Cytokines In Alzheimer’S Disease, Zhengshi Yang

UNLV Theses, Dissertations, Professional Papers, and Capstones

Alzheimer’s disease (AD) is a progressive neurodegenerative disease with the clinical symptoms of gradual cognitive decline and memory loss. Biologically, abnormal accumulation of Aβ (Aβ) plaque and tau tangles in the brain are the core pathological hallmarks in AD. Although inflammatory response is not specific to AD, emerging evidence suggests that the disrupted innate immune system within the central nervous system, particularly microglial activation, might act as the bridge linking Aβ aggregation to pathological phosphorylation and aggregation of tau. The inflammatory response was suggested to initially have a neuroprotective role of attempting to clear Aβ plaques, and then become neurotoxic …

Analyzing Sars-Cov-2 Wastewater Surveillance Data For Public Health Impact In Southern Nevada, Casey A. Barber

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Early in the COVID-19 pandemic, researchers determined that levels of severe acute respiratory coronavirus 2 (SARS-CoV-2) genetic material in wastewater could provide information about COVID-19 occurrence in communities. Wastewater-based epidemiology (WBE) efforts have subsequently expanded throughout the U.S. and internationally; the U.S. Centers for Disease Control and Prevention (CDC) initiated its National Wastewater Surveillance System (NWSS) in September of 2020 and continues its SARS-CoV-2 wastewater monitoring efforts following the end of the federal COVID-19 public health emergency in May 2023. The field of WBE has reached a critical juncture in determining the future of how SARS-CoV-2 wastewater surveillance data …

The Assignment Despite Objection Construct: Its Efficacy And Utility In Measuring Nurse-Perceived Unsafe Staffing Events And Associated Outcomes, Debra F. Fox

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose: This three-manuscript approach provided a progressively built overview of Assignment Despite Objection as a construct used by nurses to document their perceptions of unsafe staffing events and as an unstudied concept in the staffing outcomes literature.

Background: All nurses have an ethical, legal, and professional responsibility to refuse or object to assignments they believe are unsafe for their well-being or their patient’s safety. Assignment Despite Objection being the only widely used construct nurses use to document these perceptual details. No studies have focused on Assignment Despite Objection as a construct or concept, leaving a complete gap in understanding its …

Exploring Staff Nurses’ Perceptions Of Nursing Student Enculturation Within Clinical Teaching: A Focused Ethnography, Larizza Limjuco Woodruff

UNLV Theses, Dissertations, Professional Papers, and Capstones

The traditional clinical education model in nursing has utilized on-site learning experiences in clinical settings with patient encounters. With the growing complexity and demands of contemporary nursing care today, it is imperative to question the principal assumptions that guide the design and use of traditional clinical teaching experiences. Staff nurses working with nursing students can illuminate the impact of sociocultural workplace factors on clinical teaching and learning when preparing students for practice. Yet there is little known about staff nurses’ perspectives of nursing culture and how enculturation prepares nursing students for the profession. By understanding the perceptions of enculturation among …

Development And Testing The Predictability Of An Instrument Based On The Multi- Theory Model (Mtm) Of Health Behavior Change For Pre-Exposure Prophylaxis (Prep) Uptake Among People Of Color, Siddharth Raich

UNLV Theses, Dissertations, Professional Papers, and Capstones

HIV/AIDS continues to be a significant public health problem in the US and globally. In the US, it disproportionately affects people of color. In 2012, Pre-exposure Prophylaxis (PrEP) was approved by the FDA for HIV prevention. PrEP reduces the chances of acquiring HIV by 99% among people at high risk. However, PrEP uptake among people of color remains low. Therefore, this study aimed to develop and test the predictability of an instrument to describe the intent to initiate and sustain PrEP use among people of color. This research utilized an exploratory sequential mixed methods design based on the fourth-generation, multi-theory …

Cultivating Nursing Student Competency Through Serious Gaming Simulation-Enhanced Prebriefing, Shopha M. Tserotas

UNLV Theses, Dissertations, Professional Papers, and Capstones

Problem: Simulation is an effective teaching strategy for undergraduate nursing students, providing a safe environment for learning in a low-risk setting. However, students are not fully prepared to take full advantage of high-fidelity simulation activities. The purpose of this study was to examine the impact of serious gaming simulation-enhanced prebriefing on student competency and simulation effectiveness. Methodology: The study employed a quantitative, cross-sectional, quasi-experimental design using secondary data. Participants included undergraduate nursing students in a southern private university. The students were enrolled in the prelicensure nursing program and the obstetric or the transition to practice course. The control group received …

Delineating Genetic Influences On Neurodegenerative Disorders And Infectious Diseases Through Advanced Computational Methods, Xiaowei Zhuang

UNLV Theses, Dissertations, Professional Papers, and Capstones

Genetics plays a critical role in understanding the molecular mechanisms underlying neurodegenerative disorders and pathogen evolution in infectious diseases. For example, identifying genetic variants associated with a disease phenotype uncovers functional pathways that could lead to potential drug targets and therapeutic interventions. In addition, tracking the genetic evolution of pathogens enables early detection and warning of infectious disease outbreaks. In both applications, given the large amount of genetic data, advanced computational methods, including longitudinal and multivariate models, could significantly boost the statistical power and capture interrelationships among traits, environmental factors and genetic influences. This dissertation focuses on four applications of …

Influence Of Acute High-Intensity Resistance Exercise On Cognitive Performance And Prefrontal Cortex Oxygenation In Recreational Weightlifters, Samuel M. Camacho, Terence Moriarty, Mick G. Mack, Jacob P. Reed, Hyeyoung Cho

Topics in Exercise Science and Kinesiology

Acute exercise has been shown to be effective in improving post-exercise cognitive performance, including executive function. In addition, changes in prefrontal cortex (PFC) activation have been linked to any such improvements. Since resistance and higher intensity exercise is much less studied, the aim of this study was to examine the effect of high-intensity resistance exercise on cognitive performance and to determine if PFC activation was related to this cognitive performance in recreationally trained weightlifters. Ten (M = 5, F = 5) college aged (22 ± 2 years) recreationally trained weightlifters completed the Stroop task prior to and 15- and 30-min …

Factors Related To Racial Trauma Distress Among Bipoc College Students, Miguel Castano, Richard Chang, Giezel Guevarra

Undergraduate Research Symposium Posters

Racial trauma distress is when post-traumatic stress disorder symptoms occur due to repeated and cumulative experiences of racism and can negatively impacted Black, Indigenous, and people of color (BIPOC). Consensus in research findings strongly suggest that BIPOC students are more likely to experience racism on university campuses than non-BIPOC students. To mitigate some of these negative outcomes, existing research has shown that psychological safety, resilience, and intraminority solidarity are protective factors for BIPOC students experiencing race-related distress. However, little is known about the frequency of racial trauma distress among BIPOC college students and how these variables may protect against racial …

Alternatives To Screen Time Given In Parenting Advice, Emma Romeo

Undergraduate Research Symposium Lightning Talks

Screen time within the last decade is an area of rising interest, especially in a "Post-Covid" world. Despite a diversity of opinions being written and research being done on screen time, what is being presented as an alternative is lesser known. In this research, the aim is to identify types of activities that are presented to parents as alternatives' to screen time in parenting websites and blogs. This study uses qualitative content analysis of over 240 articles from 2019-2023 mentioning media use or screen time from two regularly consumed and popular parenting websites, Sheknows.com and Parents.com. The data so far …