Medicine and Health Sciences Commons^™

Photonic Designs To Reduce Morbidity And Mortality For Icu Patients On Ventilators, Jacob C. Lomonaco, Noah R. Baker, C. David Melville, Catherine A. Olivo, Matthew D. Carson, Eric J. Seibel

School of Medicine Faculty Research

Ventilator-associated pneumonia (VAP) is pneumonia that occurs >48hrs after initiation of mechanical ventilation and is a significant cause of morbidity and mortality in patients that are hospitalized in intensive care units (ICU). The risk of developing VAP increases during use, and a diagnosis of VAP has been associated with a substantial cost. There are up to hundreds of thousands of cases in the US per year, costing the healthcare system billions annually. Patients who suffer from VAP frequently require longer ICU stays, higher exposure to antibiotics, and more hospital care at the risk of increased mortality. The SARS-CoV-2 pandemic has …

The Psychometric Properties Of The Bergen–Yale Sex Addiction Scale For The Iranian Population, Samaneh Youseflu, Shane W. Kraus, Majid Yousefi Afrashteh, Soudabeh Niroomand, Fatemeh Razavinia

Psychology Faculty Research

Background: The assessment of sex addiction among different populations requires a valid and reliable tool. Since the Bergen–Yale Sex Addiction Scale (BYSAS) was not available in Iran, this study aimed to evaluate the validity and reliability of the Persian version of the BYSAS. Methods: After translation/back-translation procedure, a total of 756 Iranian men and women completed the BYSAS. The structural validity of this tool was evaluated by exploratory and confirmatory factor analyses. An expert panel review also examined content validity of the items. Psychometric properties of the scale including validity, reliability (internal consistency [Cronbach’s alpha]) and test-retest) and factor structure …

Prediction Of Obstructive Sleep Apnea Using Fast Fourier Transform Of Overnight Breath Recordings, Nicole L. Molin, Clifford Molin, Rohan J. Dalpatadu, Ashok K. Singh

Mathematical Sciences Faculty Research

The objective of this study is to address the problem of predicting the risk of obstructive sleep apnea (OSA) from overnight breath recordings collected by a subject using a smartphone or an iPhone. The dataset used in this study was collected at a health care facility and consists of breathing amplitudes of 42 subjects using the smart phone App ZeeAppnea. A total of four data mining multi-level classifiers are used on the Fast Fourier Transform (FFT) of each time series, and prediction accuracies are computed. The Random Forest (RF) and the Support Vector Machine (SVM) classifiers yielded the best results, …

Variations In Schedule Iii Prescription Patterns In A Medicaid Population Pre- And Post-Policy, Radhakrishnan Nagarajan, Jeffery Talbert, Craig S. Miller, Jeffrey Ebersole

Dental Medicine Faculty Research

The present study investigated variations in patient movement patterns between prescribers before and after House Bill 1 (HB1) implementation in Kentucky using network abstractions (PPN: prescriber-prescriber networks) from a one-month cross-sectional Schedule III prescription data in a Medicaid population. Network characteristics such as degree centrality distribution of PPN was positively skewed and revealed Dental Practitioners to be the highly connected specialty with opioid analgesic hydrocodone-acetaminophen to be the most commonly prescribed drug. Taxonomy enrichment of the prescriber specialties in PPN using chi-square test revealed a reduction in the enriched taxonomies Post-HB1 compared to Pre-HB1 with Dental practitioners being constitutively enriched …

Utility Of Multi-Theory Model (Mtm) To Explain The Intention For Pap Adherence In Newly Diagnosed Sleep Apnea Patients, Manoj Sharma, Anuj Chandra, Ryan Toth, Vinayak K. Nahar

School of Public Health Faculty Research

Purpose: The objective of this study was to assess the utility of a fourth-generation multi-theory model (MTM) in explaining the intention for initiation and sustenance of PAP adherence among newly diagnosed sleep apnea patients.
/="/">Patients and Methods: For this cross-sectional study, data were collected at a private sleep center located in the Southeastern United States. A total of 138 newly diagnosed patients with sleep apnea who had been prescribed PAP therapy completed a valid and reliable 41-item MTM instrument. Stepwise multiple regression modeling was conducted to assess MTM based explanatory variables of PAP adherence in this study sample.
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Characterization Of Dental Pulp Stem Cell Responses To Functional Biomaterials Including Mineralized Trioxide Aggregates, Sejin Bae, Bueonguk Kang, Hyungbin Lee, Harrison Luu, Eric Mullins, Karl Kingsley

Dental Medicine Faculty Research

Introduction: Many studies in stem cell biology have demonstrated that dental pulp stem cells (DPSC) may be highly proliferative and capable of pluripotent differentiation into many different tissue types. Recent advances in stem cell research have outlined methods for directing in vitro or in vivo growth, viability, and proliferation, as well as differentiation of DPSC-although much remains to be discovered. Based upon this information, the primary objective of this study was to understand the functional biomaterials needed to more effectively direct DPSC viability, growth, and proliferation. Methods: Using an approved protocol, previously collected and isolated samples of DPSC from an …

Zoonotic Diseases: New Directions In Human–Animal Pathology, Robin Bendrey, Debra Martin

Anthropology Faculty Research

Zoonotic diseases—human diseases of animal origin—represent one of the world's greatest health challenges, both today and in the past. Since the Neolithic, zoonotic diseases have been one of the major factors shaping and influencing human adaptation. Archaeology is ideally situated to provide the long view on human–animal–pathogen relationships through combining cultural, environmental and biological datasets, yet long-term studies of linked human and animal records have often been overlooked and undertheorized. The seven papers in this special issue “Zoonotic diseases: New directions in human–animal pathology” cover a range of diseases caused by bacterial, viral, and parasitic pathogens, from case studies drawn …

Risk Factors Associated With Cardiovascular Disease Among Adult Nevadans, Dieu My T. Tran, Nirmala Lekhak, Karen Gutierrez, Sheniz Moonie

Nursing Faculty Research

© 2021 Tran et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Objective Cardiovascular disease (CVD) remains the number one cause of death in the US and Nevada is ranked 11th highest for CVD mortality. The study sought to examine the association between self-reported risk factors and CVD presence among adult Nevadans, between years 2011 and 2017. Methods This is a cross-sectional, population-based study that utilized the 2011 and 2017 Nevada Behavioral Risk …

Differences In Rapid Increases In County-Level Covid-19 Incidence By Implementation Of Statewide Closures And Mask Mandates — United States, June 1–September 30, 2020, Sharoda Dasgupta, Ahmed M. Kassem, Gregory Sunshine, Tiebin Liu, Charles Rose, Gloria J. Kang, Rachel Silver, Brandy L.Peterson Maddox, Christina Watson, Mara Howard-Williams, Maxim Gakh, Russell Mccord, Regen Weber, Kelly Fletcher, Trieste Musial, Michael A. Tynan, Rachel Hulkower, Amanda Moreland, Dawn Pepin, Lisa Landsman, Amanda Brown, Siobhan Gilchrist, Catherine Clodfelter, Michael Williams, Ryan Cramer, Alexa Limeres, Adebola Popoola, Sebnem Dugmeoglu, Julia Shelburne

Environmental & Global Health Faculty Research

Background and Objective: Community mitigation strategies could help reduce COVID-19 incidence, but there are few studies that explore associations nationally and by urbanicity. In a national county-level analysis, we examined the probability of being identified as a county with rapidly increasing COVID-19 incidence (rapid riser identification) during the summer of 2020 by implementation of mitigation policies prior to the summer, overall and by urbanicity. Methods: We analyzed county-level data on rapid riser identification during June 1–September 30, 2020 and statewide closures and statewide mask mandates starting March 19 (obtained from state government websites). Poisson regression models with robust standard error …

Trends In Osteoporosis And Mean Bone Density Among Type 2 Diabetes Patients In The Us From 2005 To 2014, Yingke Xu, Qing Wu

School of Public Health Faculty Research

© 2021, The Author(s). This study aimed to examine how bone health changed among T2DM patients in the past decade. Continuous National Health and Nutrition Examination Survey (NHANES) data from 2005–2006 to 2013–2014 were analyzed to examine the trends of bone mineral density (BMD) and the prevalence trends of osteoporosis osteopenia among T2DM patients and non-diabetic people aged 40 years and older. The age- and BMI-adjusted mean BMD of the femur neck for the four NHANES cycles decreased linearly in both T2DM patients and non-diabetic people (both Plinear trend ≤ 0.009). Among women with T2DM, the mean BMD in 2013–2014 …

Is The Acsm And Friend Metabolic Equations Valid For Assessing Cardiorespiratory Fitness Among 18-34 Aged Men? : Preliminary Results, Marc-Olivier Dugas, Laurie Simard, Tommy Chevrette, Martin Lavalliere

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 2, 2021. Metabolic equations, such as ACSM and FRIEND, are used worldwide to indirectly measure the VO₂max in adults, but lack of accuracy seems to occur. 30 men of 18-34 years old performed a maximal incremental test on a treadmill during which direct VO₂max measurements was taken and then have been compared to ACSM and FRIEND metabolic equations. Point of application #1: Better evaluation and exercise prescription among athletic populations. Point of application #2: Act in prevention among sedentary and symptomatic populations. Point of application …

The Utility Of Genetic Risk Score To Improve Performance Of Frax For Fracture Prediction In Us Postmenopausal Women, Xiangxue Xiao, Qing Wu

School of Public Health Faculty Research

The ability of the fracture risk assessment tool (FRAX) in discriminating fracture and non-fracture in postmenopausal women remains suboptimal. Adding a genetic profile may improve the performance of FRAX. Three genetic risk scores (GRSs) (GRS_fracture, GRS_BMD, GRS_eBMD) were calculated for each participant in the Women’s Health Initiative Study (n = 23,981), based on the summary statistics of three comprehensive osteoporosis-related genome-wide association studies (GWAS). The primary outcomes were incident major osteoporotic fracture (MOF) and hip fracture (HF). The association between each GRS and fracture risk were evaluated in separate Cox Proportional Hazard models, with FRAX clinical risk factors adjusted for. …

Wjmsc-Derived Small Extracellular Vesicle Enhance T Cell Suppression Through Pd-L1, Meizhang Li, Rupal Soder, Sunil Abhyankar, Haitham Abdelhakim, Mitchell W. Braun, Camille V. Trinidad, Harsh B. Pathak, Ziyan Pessetto, Clayton Deighan, Siddhartha Ganguly, Buddhadeb Dawn, Joseph Mcguirk, Neil Dunavin, Andrew K. Godwin

School of Medicine Faculty Research

© 2021 The Authors. Journal of Extracellular Vesicles published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles Both mesenchymal stem cells (MSCs) and their corresponding small extracellular vesicles (sEVs, commonly referred to as exosomes) share similar immunomodulatory properties that are potentially beneficial for the treatment of acute graft versus host disease (aGvHD). We report that clinical grade Wharton's Jelly-derived MSCs (WJMSCs) secrete sEVs enriched in programmed death-ligand 1 (PD-L1), an essential ligand for an inhibitory immune checkpoint. A rapid increase in circulating sEV-associated PD-L1 was observed in patients with aGvHD and was directly associated with …

The Association Between Cardiovascular Disease Knowledge And Risk Factors Among African American Breast Cancer Survivors In The Deep South, Michelle S. Williams, Chizoba Anyimukwu

Journal of Health Disparities Research and Practice

Purpose: African American breast cancer survivors in the Deep South have a disproportionately high burden of cardiovascular disease (CVD) mortality. Multiple potentially modifiable CVD risk factors are highly prevalent in this population, such as high blood pressure, obesity, and poor dietary habits. The purpose of this study was to assess the association between CVD health metrics and heart disease knowledge among the target population.

Methods: The Heart Disease Knowledge Questionnaire was used to assess the participants’ knowledge of heart disease and heart disease risk factors. Questions from My Life Check were used to assess the participants cardiovascular health metrics. Multivariate …

Environmentally Marginalized Populations: The "Perfect Storm" For Infectious Disease Pandemics, Including Covid-19, Gabriella Y. Meltzer, Oyemwenosa Avenbuan, Christina Awada, Oluwakemi B. Oyetade, Tricia Blackman, Simona Kwon Drph, Mph, Esther Erdei Phd, Judith T. Zelikoff Phd

Journal of Health Disparities Research and Practice

COVID-19 has exacted a severe toll on the United States population’s physical and mental health and its effects have been felt most severely among people of color and low socioeconomic status. Using illustrative case studies, this commentary argues that in addition to COVID-19 health disparities created by psychosocial stressors such as the inability to socially distance and access quality healthcare, environmental justice communities have the additional burden of disproportionate exposure to toxic contaminants that contribute to their higher risk of COVID-19. Environmental contaminants including heavy metals and persistent organic pollutants found contaminating their nearby environments can alter the immune response, …

Are Binge Drinking Disparities By Sexual Identity Lower In U.S. States With Nondiscrimination Statutes That Include Sexual Orientation?, Naomi Greene, Renee M. Johnson, Joanne Rosen, Danielle German, Joanna E. Cohen

Journal of Health Disparities Research and Practice

Purpose Studies examining binge drinking disparities by sexual identity focus on intra- and inter-personal minority stressors experienced by lesbian, gay, and bisexual (LGB) populations. State-level statutes are powerful tools that can reduce health disparities. We examined how state-level nondiscrimination statutes that include sexual orientation as a protected ground (i.e., inclusive statutes) are associated with binge drinking disparities between LGB and straight adults. Methods We combined data from the 2015-2018 Behavioral Risk Factor Surveillance System (BRFSS), the Movement Advancement Project (MAP), and administrative data sources for information on binge drinking, sexual identity, nondiscrimination statutes, and individual and state-level factors. We included …

The Impact Of Food Insecurity Screenings And Community Food Resource Referrals For Patients With Type 2 Diabetes, Miriam Ngozi Ofili, Robin M. Lawson

Journal of Health Disparities Research and Practice

ABSTRACT

Approximately 50 million people in the United States are food insecure, which makes food insecurity (FI) one of the country’s most prevalent health issues. Food insecurity has been shown to be a contributing factor to uncontrolled Type 2 Diabetes (T2D), which affects about 34.1 million adults in the United States. The purpose of this study was to evaluate the effectiveness of integration of an electronic social determinants of health screening and community referral process for adult patients with T2D and FI. The aim was to determine if Hemoglobin A1c (HbA1c) levels are reduced in adult patients with T2D by …

Risk Factors Associated With Opioid Use Among African American Faith-Based Populations, Kelsey Christensen Ma, Jannette Berkley-Patton Phd, Alexandria Bauer Phd, Carole Bowe Thompson, Tacia Burgin

Journal of Health Disparities Research and Practice

African Americans (AAs) in the Midwest are more likely to die from an opioid overdose compared to Whites, despite lower rates of use. Little is known about factors related to opioid use among AAs residing in the Midwest, particularly church-affiliated AAs. AAs have the highest rate of church attendance among all racial/ethnic groups, and the Black Church may be an appropriate setting for prevention efforts. The present study sought to better understand factors related to opioid use among Midwestern church-affiliated AAs to inform future faith-based interventions. This study examined predictors of opioid use (ever) using survey data from Taking It …

Gender Disparity In Composition And Compensation Among Maryland Hospital Executives, Gilberto O. Lobaton, Majd Marrache Md, Varun Puvanesarajah Md, Dawn M. Laporte Md, Amit Jain Md, Shruti Aggarwal Md

Journal of Health Disparities Research and Practice

Introduction: Senior executive positions in hospitals have traditionally been held by men, and do not reflect the gender, racial, ethnic, and cultural diversities of the communities they serve. Despite sex parity in medical school graduates, women remain underrepresented in hospital executive leadership positions. In this study, the authors examined differences in gender composition and compensation of Maryland hospital executives.

Methods: The authors examined 47 Maryland hospitals’ publicly available tax forms from 2013-2018. Data collected included hospital revenue and executive positions’ count, salary, and gender. Executive positions included President and/or Chief Executive Officer (P/CEO), Chief Financial Officer (CFO), Chief Medical Officer …

Propelling Adolescents Toward Careers In Healthcare (Patch): A Medical Student Led Pipeline Program For High School Students Underrepresented In Medicine, Maggie Brownrigg, Sagar Patel Md, Kyle Roedersheimer Md, Melissa Wooten Md, Radhika Ghodasara Md, Banks Kooken Md, Iris Cheng Md

Journal of Health Disparities Research and Practice

Despite the growing diversity of the United States population, individuals from many racial and ethnic minority groups and low-income families continue to be underrepresented in the health professions. A diverse healthcare workforce would improve cultural competency and create a system better suited to address the vast health disparities in many disadvantaged communities, yet the current educational pipeline needs to expand opportunities to provide students traditionally underrepresented in medicine (UIM) a path to become a part of the healthcare field. The Propelling Adolescents Towards Careers in Healthcare (PATCH) program was founded to address this gap in the current health professions pipeline …

A Vicious Cycle Of Fear Of Falling Avoidance Behavior In Parkinson’S Disease: A Path Analysis, Merrill R. Landers, Kameron M. Jacobson, Nicole E. Matsunami, Hannah E. Mccarl, Michelle T. Regis, Jason K. Longhurst

Integrated Health Sciences Faculty Research

Background: Postural instability (PI) in Parkinson's disease (PD) is associated with several negative downstream consequences. Objective: The purpose was to explore the validity of a theoretical model of these downstream consequences arranged in a vicious cycle wherein PI leads to decreased balance confidence, which in turn leads to increased fear of falling (FOF) avoidance behavior, which in turn leads to decreased physical conditioning, which then feeds back and negatively affects PI. Methods: A path analysis of cross-sectional data from 55 participants with PD was conducted. The four constructs in the model connected in succession were: 1. PI (principal components analysis …

Fruit And Vegetable Consumption Behavior Among Asian Americans: A Thematic Analysis, Chia Liang Dai, Manoj Sharma, Taj Haider, Hema Sunchu

Teaching and Learning Faculty Research

© The Author(s) 2021. Consuming 5 or more cups of fruits and vegetables (F & V) per day or 400 g/day for adults is advocated by most health authorities and has short-term and long-term health benefits. There have been numerous studies examining dietary behaviors among different US populations; however, the literature on F & V consumption behavior among Asian Americans (AAs) is sparse. AAs constitute a diverse group and as their population continues to grow in the US; there is a greater need to examine the health practices of AAs and their constituent subgroups. The study aimed to conduct a …

Cancer Survivorship In Hematologic Malignancies: Lifestyle Changes After Diagnosis, Pannaga Malalur, Manas Agastya, Sandhya Wahi-Gururaj, Chad L. Cross, Delva Deauna-Limayo, Edwin C. Kingsley

School of Medicine Faculty Research

© 2020 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. Background: Studies show that patients make lifestyle changes soon after certain solid tumor diagnoses, suggesting that this may be a teachable moment to motivate and promote healthy behaviors. There is a paucity of data regarding changes made after a diagnosis of a hematologic malignancy. Methods: A cross-sectional study of 116 patients at a community oncology center who completed anonymous questionnaires was performed. Questions addressed lifestyle choices made with respect to smoking, alcohol consumption, recreational drug use, diet, and exercise habits before and after diagnosis of a hematologic …

The Motivation And Confidence In Choosing Dentistry As A Career Amongst Dental Students: A Mixed-Methods Study, Mai E. Khalaf, Neamat H. Abubakr, Hanadi Alenezi, Hassan Ziada

Dental Medicine Faculty Research

© 2021 The Authors. European Journal of Dental Education published by John Wiley & Sons Ltd. Objectives: An insight into students’ motivation and confidence in the choice of entering and remaining in dental education is essential. The understanding of how choices are made can help universities in the planning of admission policies. This study aimed to evaluate the career choice influences, motivation and confidence in the choices made into dental education. Methods: A mixed-method design was employed, using both quantitative and qualitative data. One hundred seventy-three questionnaires were distributed to all registered dental students, with a response rate of 85%. …

Associations Between Stress, Anxiety, Depression, And Emotional Intelligence Among Osteopathic Medical Students, Nicole A. Doyle, Robert E. Davis, Syed Siraj A. Quadri, Joshua R. Mann, Manoj Sharma, Richard M. Wardrop, Vinayak K. Nahar

Environmental & Global Health Faculty Research

Context: Stress, anxiety, and depression affect medical student populations at rates disproportionate to those of general student populations. Emotional intelligence (EI) has been suggested as a protective factor in association with psychological distress. Objective: To explore the relationships between EI and stress, anxiety, and depression among a sample of US osteopathic medical students. Methods: From February to March 2020, a convenience sample of medical students enrolled at an osteopathic medical school in the southeastern region of the United States were invited to complete a voluntary and anonymous 54-item online questionnaire that included sociodemo-graphic items as well as validated and reliable …

Remote Teaching Of Research Methods, Manoj Sharma

UNLV Best Teaching Practices Expo

Research Methods (PBH 360-1002) offered by the School of Public Health was taught remotely by Manoj Sharma to undergraduate students (primarily from public health) in Fall 2020. The specific teaching techniques that were used in teaching this course were delivery as remote learning, organizing the entire course in Canvas and making it available from day 1, recording all lectures beforehand in Panopto, utilizing cases studies, employing WebEx and its breakout sessions, and having skill-building activities in each module that were sequential. In this course, the fourth-generation multi-theory model (MTM) of health behavior change was utilized from a pedagogical perspective to …

Utilizing Plastinated Head And Neck Dissections For Doctorate Of Dental Medicine (Dmd) Anatomy Laboratories : Observations From The Den 7109 “Guinea Pig” Course, Jessica Immonen

UNLV Best Teaching Practices Expo

This poster documents use of digital dissection tutorials in place of in-person laboratory time for a gross anatomy course in a dental medicine doctorate (DMD) program. Tutorials were developed with a standard digital camera and Camtasia video editing software. Plastinated head and neck specimens prepared by the Von Hagens company in Germany were used in place of standard, embalmed cadaveric donors. Initial student feedback (N=40) indicated that the tutorials were helpful/very helpful (100%), clinically relevant/very clinically relevant (97.5%), were impactful on content retention (100%) and were appropriate/very appropriate with respect to length (3-8 min; 97.5%). After these initial findings were …

Auricular Point Acupressure Smartphone Application To Manage Chronic Musculoskeletal Pain: A Longitudinal, One-Group, Open Pilot Trial, Jennifer Kawi, Chao Hsing Yeh, Mengchi Li, Keenan Caswell, Maurice Mazraani, Nada Lukkahatai, Sylvanus Mensah, Janiece Taylor, Chakra Budhathoki, Paul Christo

Nursing Faculty Research

Background: Chronic musculoskeletal pain (CMP) is the most common self-reported chronic pain condition. Current treatment for CMP is limited. Methods: This was a two-phase study. In Phase 1, three auricular point acupressure (APA)-naïve participants were recruited to explore their experiences of APA and a smartphone app was developed based on their feedback. In Phase 2, a prospective longitudinal study was used to examine the effectiveness of the smartphone app to self-manage CMP. Results: Phase 1 resulted in the successful development of the APA smartphone app. In Phase 2, after four weeks of APA, participants reported reduced pain intensity (30%), pain …

Important Updates To Submission Types In Topics In Exercise Science And Kinesiology, James W. Navalta, Donald L. Hoover, Robert Salatto, Whitley J. Stone, Scott Lyons

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 1, 2021. While Topics in Exercise Science and Kinesiology (TESK) was originally designed to fill a void in publishing applied information for practitioners in physical activity and sport, the TESK editors have determined a need to update the submission categories. The categories of Process of Science and Implementation Strategies have been retained, and three new types of submissions now will be accepted: Expedited Articles, Review Articles, and Case Studies. Process of Science submissions should seek to answer the question, “What was learned from the experience of performing the investigation?”, …

Eus-Guided Pelvic Drainage: A Systematic Review And Meta-Analysis, Banreet Singh Dhindsa, Yassin Naga, Syed Mohsin Saghir, Amaninder Dhaliwal, Daryl Ramai, Chad Cross, Shailender Singh, Ishfaq Bhat, Douglas G. Adler

School of Medicine Faculty Research

Background and Objectives: EUS-guided pelvic abscess drainage (EUS-PAD) is a procedure that utilizes an echoendoscope to visualize an area of interest for needle insertion and placement of a stent, catheter, or both for drainage of the target abscess. The aim of this study was to perform a systematic review and meta-analysis for the safety and efficacy of EUS-PAD. Materials and Methods: We conducted a comprehensive search of several databases and conference proceedings including PubMed, EMBASE, Google Scholar, MEDLINE, SCOPUS, and Web of Science databases (earliest inception to February 2020). The primary outcomes for this study were the technical and clinical …