Medicine and Health Sciences | Open Access Articles

Research News. Publications, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period October 1 through December 31, 2019

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Research News. Grants, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during October-December 2019

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Development And Validation Of A High-Performance Thin-Layer Chromatographic Method For The Quantitative Analysis Of Vitexin In Passiflora Foetida Herbal Formulations, Ahmed Ibrahim Foudah, Prawez Alam, Y. T. Kamal, Saleh Ibrahim Alqasoumi, Mohammed Hamed Alqarni, Samir A. Ross, Hasan Soliman Yusufoglu

Faculty and Student Publications

© 2019 Dehon et al. Introduction: Formative evaluations of clinical teaching for emergency medicine (EM) faculty are limited. The goal of this study was to develop a behaviorally-based tool for evaluating and providing feedback to EM faculty based on their clinical teaching skills during a shift. Methods: We used a three-phase structured development process. Phase 1 used the nominal group technique with a group of faculty first and then with residents to generate potential evaluation items. Phase 2 included separate focus groups and used a modified Delphi technique with faculty and residents, as well as a group of experts to …

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Experimental Investigation Examining The Effects Of Acute Exercise On Implicit Memory Function, Paul D. Loprinzi, Morgan Gilbert, Gina Robinson, Briahna Dickerson

Faculty and Student Publications

© 2019, PsychOpen. All rights reserved. Emerging work suggests that acute exercise can enhance explicit memory function. Minimal research, however, has examined whether acute exercise is associated with implicit memory, which was the purpose of this study. Three separate experimental studies were computed (N = 120; Mean age = 21). In Experiment 1, participants were randomly assigned to either a moderate-intensity bout of acute exercise (15-minute) or engaged in a seated control task (15-minute), followed by the completion of a word-fragmentation implicit memory task. Experiment 2 replicated Experiment 1, but instead employed a higher-intensity exercise protocol. For Experiment 3, participants …

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Research News. Publications, 2019. Volume 3, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period July 1 through September 30, 2019

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A Baker's Dozen Of Top Antimicrobial Stewardship Intervention Publications In 2018, Elias B. Chahine, Spencer H. Durham, Krutika N. Mediwala, Daniel B. Chastain, Timothy P. Gauthier, Brandon K. Hill, Bruce M. Jones, Jamie J. Kisgen, Ashley H. Marx, Kayla R. Stover, Marylee V. Worley, Christopher M. Bland, P. Brandon Bookstaver

Faculty and Student Publications

© The Author(s) 2019 Phytochemical investigation of methanolic extract of Limonium leptophyllum (Plumbaginaceae), led to the isolation of 1 new isoflavonoid with a rare 5-membered dihydrofuran ring (1, leptoisoflavone A) and 8 known compounds. The known isolated compounds were identified as euchrenone b9 (2), auriculasin (3), kaempferol (4), avicularoside (5), myrice-tin-3-arabinoside (6), trans-N-feruloyltyramine (7), trans-N-caffeoyltyramine (8), and β-sitosterol (9). The crude methanolic extract exhibited moderate activity toward endocannabinoid receptors. Auriculasin (3) showed activity toward cannabinoid receptor type 1 (86.7% displacement with IC50 8.92 μM).

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Research News. Grants, 2019. Volume 3, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during July-September 2019

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Persistent Organic Pollutants (Pops) Increase Rage Signaling To Promote Downstream Cardiovascular Remodeling, Jackson B. Coole, Stephanie S. Burr, Amber M. Kay, Jaime A. Singh, Sandeep Kondakala, Eun Ju Yang, Barbara L.F. Kaplan, George E. Howell, James A. Stewart

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Background: Antimicrobial resistance (AMR) is a global threat and the antimicrobial stewardship program (ASP) is a globally used tool to combat AMR. There is little information on the views among Pakistani physicians regarding AMR and the benefits of hospital antimicrobial stewardship implementation. This study was designed to explore the physicians’ views about ASP. Methods: Qualitative face-to-face and telephonic interviews were conducted by using purposive sampling method with 22 physicians working in seven tertiary care public hospitals of Punjab, Pakistan. All interviews were audio recorded and transcribed verbatim. Qualitative software was used, …

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Silver Nanoparticle Synthesis By Acalypha Wilkesiana Extract: Phytochemical Screening, Characterization, Influence Of Operational Parameters, And Preliminary Antibacterial Testing, Adewumi Oluwasogo Dada, Folahan Amoo Adekola, Fehintoluwa Elizabeth Dada, Adunola Tabitha Adelani-Akande, Micheal Oluwasesan Bello, Chidiogo Rita Okonkwo, Adejumoke Abosede Inyinbor, Abimbola Peter Oluyori, Adeniyi Olayanju, Kolawole Oluseyi Ajanaku, Charles Oluwaseun Adetunji

Faculty and Student Publications

© 2019, The Author(s). Introduction: The application of skin bleaching products to inhibit melanogenesis is a common practice within the African diaspora. Despite the adverse health effects of skin bleaching, rigorous studies investigating skin bleaching behavior among these populations in the United States are limited. In our P30 pilot study, we explored predictors of skin bleaching practice intensity among African and Afro-Caribbean women. Methods: In collaboration with our Community Engagement Core, we conducted a cross-sectional study to investigate the relationship between demographic and psychosocial predictors and skin-bleaching-related practice patterns among African and Afro-Caribbean women in New York City. Results: Among …

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Determining The Binding Site Of Org27569 Within The Cb1 Receptor, Ayooluwa O. Aderibigbe, Pankaj Pandey, Robert J. Doerksen

Faculty and Student Poster Sessions

Computational studies to determine the binding site of ORG27569, a negative allosteric modulator, within the cannabinoid receptor 1 (CB1) reveal an intracellular binding domain as the most favorable binding site for ORG27569.

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Promising Activity Of Anthemis Austriaca Jacq. On The Endometriosis Rat Model And Isolation Of Its Active Constituents, Mert Ilhan, Zulfiqar Ali, Ikhlas A. Khan, Hakkı Taştan, Esra Küpeli Akkol

Faculty and Student Publications

© 2019, The Author(s). Heparin and heparan sulfate (Hp/HS) are linear complex glycosaminoglycans which are involved in diverse biological processes. The structural complexity brings difficulties in separation, making the study of structure-function relationships challenging. Here we present a separation method for Hp/HS oligosaccharide fractionation with cross-compatible solvent and conditions, combining size exclusion chromatography (SEC), ion-pair reversed phase chromatography (IPRP), and hydrophilic interaction chromatography (HILIC) as three orthogonal separation methods that do not require desalting or extensive sample handling. With this method, the final eluent is suitable for structure-function relationship studies, including tandem mass spectrometry and microarray printing. Our data indicate …

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Δ9-Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure In Normotensive Rabbits, Pranjal S. Taskar, Akash Patil, Prit Lakhani, Eman Ashour, Waseem Gul, Mahmoud A. Elsohly, Brian Murphy, Soumyajit Majumdar

Faculty and Student Publications

No abstract provided.

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High-Intensity Acute Exercise And Directed Forgetting On Memory Function, Mary Elizabeth Pace, Paul D. Loprinzi

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Background and Objectives: Despite accumulating research demonstrating that acute exercise may enhance memory function, very little research has evaluated whether acute exercise can effectuate intentional directed forgetting (DF), an adaptative strategy to facilitate subsequent memory performance. Materials and Methods: A three-arm parallel-group randomized controlled intervention was employed. Participants were randomized into one of three groups, including: (1) exercise plus DF (Ex + DF), (2) DF (directed forgetting) only (DF) and (3) R (remember) only (R). The acute bout of exercise included 15 min of high-intensity treadmill exercise. The memory assessment involved …

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Research News. Publications, 2019. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period April 1 through June 30, 2019

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Research News. Grants, 2019. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during April-June 2019

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The Association Of Handgrip Strength And Mortality: What Does It Tell Us And What Can We Do With It?, Samuel L. Buckner, Scott J. Dankel, Zachary W. Bell, Takashi Abe, Jeremy P. Loenneke

Faculty and Student Publications

© Copyright 2019, Mary Ann Liebert, Inc., publishers 2019. The relationship between grip strength and mortality is often used to underscore the importance of resistance exercise in physical activity guidelines. However, grip strength does not appear to appreciably change following traditional resistance training. Thus, grip strength could be considered reflective of strength independent of resistance exercise. If true, grip strength is not necessarily informing us of the importance of resistance exercise as an adult, but potentially highlighting inherent differences between individuals who are stronger at "baseline" compared to their weaker counterpart. The purpose of this article is to discuss: (1) …

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Bone Mineral Density Among Men And Women Aged 35 To 50 Years, Martha A. Bass, Ankita Sharma, Vinayak K. Nahar, Stacy Chelf, Brittany Zeller, Linda Pham, M. Allison Ford

Faculty and Student Publications

© 2019 American Osteopathic Association. Context: Osteoporosis is characterized by low bone mineral density (BMD) and has been thought to only be a major health concern for postmenopausal women. However, osteoporosis and its risk factors have been greatly understudied in the middle-aged and male populations. Objective: To assess the likelihood of low BMD and its association with related risk factors in early–middle-aged (defined in this study as 35-50 years) men and women.Methods: Eligible men and women completed a questionnaire assessing calcium intake, hours per week of exercise, and other related risk factors associated with osteoporosis and osteopenia. The primary outcome …

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Interventions To Increase Uptake Of The Human Papillomavirus Vaccine In Unvaccinated College Students: A Systematic Literature Review, Marie Barnard, Anna C. Cole, Lori Ward, Emily Gravlee, Mariah L. Cole, Caroline Compretta

Faculty and Student Publications

© 2019, American Association of Colleges of Pharmacy. All rights reserved. The Committee was charged with the responsibility for examining the need for change in pharmacy education and the models of leadership that would enable that change to occur across the academy. They also examined the question of faculty wellbeing in a time of change and made several recommendations and suggestions regarding both charges. Building upon the work of the previous Academic Affairs Committee, the 2018-19 AAC encourages the academy to implement new curricular models supporting personalized learning that creates engaged and lifelong learners. This will require transformational leadership and …

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Nutritional Knowledge And Behaviors Of Undergraduate Students, Victoria Inghram

Honors Theses

Poor dietary behavior can lead to various chronic health conditions, such as heart disease and obesity. Because dietary intake takes time to impact health, observing diet knowledge in college students can be beneficial. This study sought to measure whether greater nutritional knowledge would translate to a healthier dietary intake. Nutritional knowledge and behavior were measured and then compared in 257 students in two different undergraduate classes - an introductory nutrition course and a standard biology course - which was the control group. Each class was given the same survey at the beginning and end of the fall semester. Results indicated …

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Molecular Nickel-Catalysts For Photocatalytic Reduction Of Co2, Harshin U. Sanjanwala

Honors Theses

Increased atmospheric CO2 has been the result of prominent usage of fossil fuels as a fuel source. As fossil fuels are a nonrenewable energy source, scientists are looking towards more renewable energy resources capable of both efficiently producing energy and reducing atmospheric CO2-emissions. A photocatalyst with an earth-abundant metal capable of chemically reducing CO2 paired with only water and photon inputs would provide a solution to these pressing issues. Here, studies were performed on three catalysts, each with a nickel metal center. Each catalyst went through a series of photocatalytic tests in various conditions to identify whether a catalyst was …

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Modification Of Hiv-1 Protease Inhibitor Pharmacophore To Assess Anti-Malarial Properties, Margaret Ann Street

Honors Theses

For years, the human immunodeficiency virus type 1 (HIV-1) and malarial parasites have both been prevalent in sub-Saharan Africa. Coinfections of HIV-1 and malaria are common in areas of geographic overlap as both infections seem to increase the severity of the other. HIV-1 treatments have shown to decrease the Plasmodium infections resulting in a lower malarial incidence. HIV-1 protease inhibitors target a crucial step in the life cycle required for viral maturation and have demonstrated a lower level of resistance compared with other therapies. Recent studies have shown the treatment of HIV-1 with protease inhibitors has resulted in inhibitory effects …

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Neurotoxic Effects Of Hiv-1 Gp120 And Interaction With Allopregnanolone, Kimberly A. Thornton

Honors Theses

With increasing incidence of HIV and its associated neurocognitive disorders, there has emerged a need for an antiviral with improved delivery to the CNS. In searching for drug candidates that meet these criteria, some have noted that certain steroid hormones like estrogen and progesterone that naturally accumulate in the CNS show neuroprotective effects in cells exposed to HIV proteins. This investigation focused on testing the potential protective effects of the progesterone metabolite, allopregnanolone (AlloP), against HIV protein gp120-mediated neurotoxicity. Experiments were conducted using SH-SY5Y neuroblastoma cells that were exposed to varying concentrations of AlloP (0-100 nM) in conjunction with one …

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A Comprehensive Examination Of University Of Mississippi Early Entry Students’ Perceptions Of Mental Illness, Brianna Gray

Honors Theses

Mental disorders affect nearly 1 in 5 adults in the United States in a given year, and that number is steadily increasing. Pharmacists, being some of the most accessible and frequently contacted health care professionals, must be prepared to provide support for these patients. They can play a key role in whether or not there is a positive patient outcome. Education can play a role in pharmacists’ comfort with and knowledge of mental illness. The primary objective of this study was to determine if University of Mississippi early-entry pharmacy students’ mental illness knowledge, familiarity, and acceptable social distance affected their …

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Auditory Verbal Hallucinations In Schizophrenia, Katherine Joiner

Honors Theses

The primary auditory cortex being linked to the AVHs could be due to it being overly sensitive when being stimulated by processing found internally, opposing to outward stimulation. The 173 individuals who were available for both structural data and resting state, 83 were found to have schizophrenia or schizoaffective. Resting state echo planar image (EPI) volumes had 32 slices of 4mm 64x64 matrix with 4mm thickness (voxel size = 3x3x4mm), with repetition time (TR) of 2000ms and echo time (TE) of 29ms. A total of 150 volumes (5 minutes) were used in the analysis. The auditory cortex in the SZ …

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A New Prenylated Isoflavonoid From Limonium Leptophyllum, Asset Dizamatova, Kamila Zhumanova, Galiya E. Zhusupova, Aizhan I. Zhussupova, Radhakrishnan Srivedavyasasri, Mohamed A. Ibrahim, Samir A. Ross

Faculty and Student Publications

© 2019, Mary Ann Liebert, Inc., publishers 2019. Purpose: Cannabidiol (CBD), active component of plant Cannabis sativa, has anti-inflammatory properties that could potentially help treat diabetic retinopathy-induced pain and inflammation. However, CBD is a lipophilic molecule making its topical delivery to back of the eye challenging. This study aims at improving ocular penetration of CBD by means of analog derivatization. Methods: Analogs were designed using various ligands, such as amino acids (AAs) and dicarboxylic acids (DCAs) and their combinations. Select analogs were screened in vitro with respect to their stability in ocular tissue homogenates. Based on in vitro stability, analogs …

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Dietary Supplement Safety: A 25 Year Retrospective Assessment, Bill Gurley

Oxford ICSB

Passage of the Dietary Supplement Health & Education Act (DSHEA) in 1994 ushered in a new category of consumer products known as dietary supplements (DS). DSHEA’s definition of a dietary supplement encompasses a wide variety of products from multivitamins and single-ingredient botanical extracts, to “proprietary blends” of multiple botanical extracts and/or vitamins and minerals. Almost from their inception, safety concerns regarding certain categories of “proprietary blends” have plagued the DS industry. Most notable of these involved Ephedra-containing DS, whose questionable safety record led to their removal from the U.S. market in 2004 by the FDA after a 10-year period of …

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Research News. Grants, 2019. Volume 1, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during January-March 2019

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Research News. Publications, 2019. Volume 1, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period January 1 through March 31, 2019

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Arabinoxyloglucan Oligosaccharides May Contribute To The Antiadhesive Properties Of Porcine Urine After Cranberry Consumption, Christina M. Coleman, Kimberly M. Auker, K. Brian Killday, Parastoo Azadi, Ian Black, Daneel Ferreira

Faculty and Student Publications

© 2019 As part of our continuing investigation for interesting biological activities of native medicinal plants, thirty-nine plants, obtained from diverse areas in Saudi Arabia and Yemen, were screened for insecticidal activity against yellow fever mosquito Aedes aegypti (L.). Out of the 57 organic extracts, Saussurea lappa, Ocimum tenuiflorum, Taraxacum officinale, Nigella sativa, and Hyssopus officinalis exhibited over 80% mortality against adult female Ae. aegypti at 5 μg/mosquito. In the larvicidal bioassay, the petroleum ether extract of Aloe perryi flowers showed 100% mortality at 31.25 ppm against 1st instar Ae. aegypti larvae. The ethanol extract of Saussurea lappa roots was …

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Request For Applications: Neuroscience Summer Research Education Program, University Of Mississippi. Brain Wellness Constellation

Brain Wellness

The Brain Wellness Undergraduate Summer Research Program is an initiative of the UM-UMMC Flagship Constellations. The program will provide stipends to undergraduate students for collaborative research experiences in neuroscience related to brain wellness. In this way it will serve to develop new pipelines for pre-graduate and pre-medical students interested in neuroscience to gain research experience and develop collaborative connections between neuroscience faculty at the Oxford and Jackson campuses.

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Full-Text Articles in Medicine and Health Sciences

Research News. Publications, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Research News. Grants, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Faculty and Student Publications

Experimental Investigation Examining The Effects Of Acute Exercise On Implicit Memory Function, Paul D. Loprinzi, Morgan Gilbert, Gina Robinson, Briahna Dickerson

Faculty and Student Publications

Research News. Publications, 2019. Volume 3, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Faculty and Student Publications

Research News. Grants, 2019. Volume 3, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Persistent Organic Pollutants (Pops) Increase Rage Signaling To Promote Downstream Cardiovascular Remodeling, Jackson B. Coole, Stephanie S. Burr, Amber M. Kay, Jaime A. Singh, Sandeep Kondakala, Eun Ju Yang, Barbara L.F. Kaplan, George E. Howell, James A. Stewart

Faculty and Student Publications

Faculty and Student Publications

Determining The Binding Site Of Org27569 Within The Cb1 Receptor, Ayooluwa O. Aderibigbe, Pankaj Pandey, Robert J. Doerksen

Faculty and Student Poster Sessions

Promising Activity Of Anthemis Austriaca Jacq. On The Endometriosis Rat Model And Isolation Of Its Active Constituents, Mert Ilhan, Zulfiqar Ali, Ikhlas A. Khan, Hakkı Taştan, Esra Küpeli Akkol

Faculty and Student Publications

Δ9-Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure In Normotensive Rabbits, Pranjal S. Taskar, Akash Patil, Prit Lakhani, Eman Ashour, Waseem Gul, Mahmoud A. Elsohly, Brian Murphy, Soumyajit Majumdar

Faculty and Student Publications

High-Intensity Acute Exercise And Directed Forgetting On Memory Function, Mary Elizabeth Pace, Paul D. Loprinzi

Faculty and Student Publications

Research News. Publications, 2019. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Research News. Grants, 2019. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

The Association Of Handgrip Strength And Mortality: What Does It Tell Us And What Can We Do With It?, Samuel L. Buckner, Scott J. Dankel, Zachary W. Bell, Takashi Abe, Jeremy P. Loenneke

Faculty and Student Publications

Bone Mineral Density Among Men And Women Aged 35 To 50 Years, Martha A. Bass, Ankita Sharma, Vinayak K. Nahar, Stacy Chelf, Brittany Zeller, Linda Pham, M. Allison Ford

Faculty and Student Publications

Interventions To Increase Uptake Of The Human Papillomavirus Vaccine In Unvaccinated College Students: A Systematic Literature Review, Marie Barnard, Anna C. Cole, Lori Ward, Emily Gravlee, Mariah L. Cole, Caroline Compretta

Faculty and Student Publications

Nutritional Knowledge And Behaviors Of Undergraduate Students, Victoria Inghram

Honors Theses

Molecular Nickel-Catalysts For Photocatalytic Reduction Of Co2, Harshin U. Sanjanwala

Honors Theses

Modification Of Hiv-1 Protease Inhibitor Pharmacophore To Assess Anti-Malarial Properties, Margaret Ann Street

Honors Theses

Neurotoxic Effects Of Hiv-1 Gp120 And Interaction With Allopregnanolone, Kimberly A. Thornton

Honors Theses

A Comprehensive Examination Of University Of Mississippi Early Entry Students’ Perceptions Of Mental Illness, Brianna Gray

Honors Theses

Auditory Verbal Hallucinations In Schizophrenia, Katherine Joiner

Honors Theses

A New Prenylated Isoflavonoid From Limonium Leptophyllum, Asset Dizamatova, Kamila Zhumanova, Galiya E. Zhusupova, Aizhan I. Zhussupova, Radhakrishnan Srivedavyasasri, Mohamed A. Ibrahim, Samir A. Ross

Faculty and Student Publications

Dietary Supplement Safety: A 25 Year Retrospective Assessment, Bill Gurley

Oxford ICSB

Research News. Grants, 2019. Volume 1, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Research News. Publications, 2019. Volume 1, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Arabinoxyloglucan Oligosaccharides May Contribute To The Antiadhesive Properties Of Porcine Urine After Cranberry Consumption, Christina M. Coleman, Kimberly M. Auker, K. Brian Killday, Parastoo Azadi, Ian Black, Daneel Ferreira

Faculty and Student Publications

Request For Applications: Neuroscience Summer Research Education Program, University Of Mississippi. Brain Wellness Constellation

Brain Wellness