Medicine and Health Sciences Commons^™

The Effect Of Three Foot Orthoses On Plantar Pressure Under The First Metatarsophalangeal Joint Of Pes Planus Foot Type During Standing And Slow Running, Lacey Ann Nordsiden

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to examine the effect of three different foot orthoses on plantar pressure under the first metatarsophalangeal joint during standing and slow running. Twenty physically active participants, 12 males (19.7±1.3 years, 181.5±6.3cm, 83.6±12.3kg) and 8 females (20.8±1.5 years, 172.7±11.2cm, 69.9±14.2kg) with navicular drop greater than 10mm, no history of surgery to the lower extremity, and no history of pain or injury to the 1st metatarsophalangeal joint in the past six months volunteered for the study. Each subject performed standing and slow running tasks with four different orthosis conditions: no orthosis, metatarsal dome, U-shaped orthosis, and …

An Assessment Of High School Coaches Knowledge Of Sport-Related Concussion, Erin M. O'Donoghue

Human Movement Studies & Special Education Theses & Dissertations

Sport-related concussion is a common occurrence in high-risk sports and can occur during participation in all sports. The purpose of this study was to assess the knowledge base high school athletic coaches possess about concussion signs and symptoms in regards to recognition, management, and prevention of this condition. A 25 question demographic questionnaire was used to gather background information and a 24 question multiple-choice assessment was used to determine knowledge of recognition, management, and prevention of sport-related concussion. A panel of eight experts in the fields of sport-related concussion and/or survey research reviewed and modified the survey instrument, which were …

Effects Of Tooth Whitening Use On Oral Health Interests And Values In Adults, Katie Jo Ballantyne Sargent

Dental Hygiene Theses & Dissertations

The primary purpose of this study was to determine if tooth whitening product use influences oral health interests and values in an adult population. A two-group, randomized, pre-test, multiple post-test design was used for studying 60 adults between the ages of 18 and 60. Persons who use tobacco products, have composite/tooth-colored anterior restorations, less than eight anterior teeth, pregnant or lactating women, or those who have previously used a whitening product other than toothpaste were excluded from the study. At baseline, a researcher-designed Oral Health Questionnaire was administered to consenting adults to determine the level of oral health interests and …

Staphylococcal Cassette Chromosome Mec And Panton-Valentine Leukocidin Characterization Of Methicillin-Resistant Staphylococcus Aureus Clones, Shannon M. Moroney, Loree C. Heller, Jesse Arbuckle, Monica Talavera, Ray H. Widen

Bioelectrics Publications

Staphylococcal cassette chromosome mec (SCCmec) types and Panton-Valentine leukocidin (PVL) gene carriage were compared among suspected community-associated methicillin-resistant Staphylococcus aureus MRSA (CA-MRSA) and health care-associated MRSA (HA-MRSA) isolates. CA-MRSA isolates carried the SCCmec type IV complex, and most were PVL positive. The HA-MRSA isolates carried the SCCmec type II complex and did not harbor the PVL genes.

Depression: Relationships To Sleep Paralysis And Other Sleep Disturbances In A Community Sample, Mariana Szklo-Coxe, Terry Young, Laurel Finn, Emmanuel Mignot

Community & Environmental Health Faculty Publications

Sleep disturbances are important correlates of depression, with epidemiologic research heretofore focused on insomnia and sleepiness. This epidemiologic study’s aim was to investigate, in a community sample, depression’s relationships to other sleep disturbances: sleep paralysis (SP), hypnagogic/hypnopompic hallucinations (HH), cataplexy – considered rapid eye movement-related disturbances – and automatic behavior (AB). Although typical of narcolepsy, these disturbances are prevalent, albeit under-studied, in the population. Cross-sectional analyses (1998–2002), based on Wisconsin Sleep Cohort Study population-based data from 866 participants (mean age 54, 53% male), examined: depression (Zung Self-Rating Depression Scale), trait anxiety (Spielberger State-Trait Anxiety Inventory, STAI-T ≥ 75th percentile), and …

Changing Perspectives On The Use Of Antimicrobial Mouthrinses, Michele Leonardi Darby

Dental Hygiene Faculty Publications

As oral health care professionals, we need to make evidence-based recommendations to our patients. Studies from which we derive our recommendations need to have been conducted with scientific rigor and need to be confirmed with other welldesigned studies. Given the numerous, long-term, peer-reviewed published studies on antimicrobial mouthrinses with consistent statistically and clinically significant outcomes, it is time to change our professional thinking and practices.

The Cost-Effectiveness Of Improving Diabetes Care In U.S. Federally Qualified Community Health Centers, Elbert S. Huang, Qi Zhang, Sydney E. S. Brown, Melinda L. Drum, David O. Meltzer, Marshall H. Chin

Community & Environmental Health Faculty Publications

Objective. To estimate the incremental cost-effectiveness of improving diabetes care with the Health Disparities Collaborative (HDC), a national collaborative quality improvement (QI) program conducted in community health centers (HCs).

Data Sources/Study Settings. Data regarding the impact of the Diabetes HDC program came from a serial cross-sectional follow-up study (1998, 2000, 2002) of the program in 17 Midwestern HCs. Data inputs for the simulation model of diabetes came from the latest clinical trials and epidemiological studies.

Study Design. We conducted a societal cost-effectiveness analysis, incorporating data from QI program evaluation into a Monte Carlo simulation model of diabetes.

Data Collections/Extraction …

Self-Consistent Analyses For Potential Conduction Block In Nerves By An Ultrashort High-Intensity Electric Pulse, R. P. Joshi, A. Mishra, Q. Hu, K. H. Schoenbach, A. Pakhomov

Bioelectrics Publications

Simulation studies are presented that probe the possibility of using high-field (>100kV ∕ cm), short-duration (∼50ns) electrical pulses for nonthermal and reversible cessation of biological electrical signaling pathways. This would have obvious applications in neurophysiology, clinical research, neuromuscular stimulation therapies, and even nonlethal bioweapons development. The concept is based on the creation of a sufficiently high density of pores on the nerve membrane by an electric pulse. This modulates membrane conductance and presents an effective "electrical short" to an incident voltage wave traveling across a nerve. Net blocking of action potential propagation can then result. A continuum approach based …

Changes In Formal-Informal Caregiving In Elderly Stroke Survivors, Holly Anne Beard

Health Services Research Dissertations

The purpose of this study is to determine the extent to which the Andersen and Aday Model of Health Services Use to predict cross-sectional and longitudinal differences in the caregiving source among stroke survivors (n=477) over a six-year period. This study involves a secondary analysis of a longitudinal panel study focusing upon three waves of interview data from the HAS/AHEAD study spanning 1998 through 2002. Multinomial logistic regression was utilized to examine caregiving source cross-sectionally at each wave. Clustered multinomial logistic regression was used to examine relationships between predictor variables in the model and caregiving source across waves while holding …

Unruly Corporeality: Aids, Immigration And The Imagined Australian Body, Zoë Anderson

Reconstruction: Studies in Contemporary Culture

Particular bodies within the Australian nation can be seen to threaten to disrupt and destabilize dominant notions of cultural citizenship. Understood through intricate intersections of ethnicity, gender and sexuality, 'Australianness' - and its correlation to the geographical nation - is constantly monitored. Crucial here is the manner in which boundaries of whiteness, and 'true Australianess', are reconstituted, fuelling avoidance of the ambiguities of national belonging and ensuring the enduring pathologisation of the 'un'Australian. In particular, discursive associations between HIV/AIDS and the 'foreign' as perceived contaminates to the nation operate to reinforce these understandings. Here, the threat of disease both informs, …

Theorizing Threat: An Investigation Of Contentious Embodiment, Jennifer Musial, Emily Van Der Meulen

Reconstruction: Studies in Contemporary Culture

[First paragraph]

In early summer 2006, we had a phone conversation that generated interest in this topic. Emily was reminiscing about her experiences at the Washington, D.C. March for Women's Lives in April of 2004. The March, a demonstration for reproductive justice, brought out feminists and anti-abortion protestors alike. Emily remembered seeing African-American men holding signs that equated abortion to the airplane attacks in New York City on September 11, 2001. This sparked curiosity: how does abortion become equated with "terrorism"? [1] One answer to this question is that a woman who has an abortion is said to commit "body-terrorism" …

From Adulterous Gametes To Heterologous Nation: Tracing The Boundaries Of Reproduction In Italy, Milena Marchesi

Reconstruction: Studies in Contemporary Culture

This article traces discursive and political attempts to discipline the reproduction of the Italian nation by analyzing the approval of a controversial law disciplining access to new reproductive technologies (NRTs) in 2004. The restriction of new reproductive technologies in Italy reflects a contemporary re-negotiation of gender ideologies and a renewed ascendance of the Vatican in Italian politics and society. Although abortion remains legal in Italy, the NRT legislation recognizes the embryo as a subject while in political discourse demographic alarmism slides into warnings of social disintegration. The debate over the threat posed by technologically assisted reproduction to Italian families and …

An Epidemiological Model Of Rift Valley Fever, Holly D. Gaff, David M. Hartley, Nicole P. Leahy

Biological Sciences Faculty Publications

We present and explore a novel mathematical model of the epidemiology of Rift Valley Fever (RVF). RVF is an Old World, mosquito-borne disease affecting both livestock and humans. The model is an ordinary differential equation model for two populations of mosquito species, those that can transmit vertically and those that cannot, and for one livestock population. We analyze the model to find the stability of the disease-free equlibrium and test which model parameters affect this stability most significantly. This model is the basis for future research into the predication of future outbreaks in the Old World and the assessment of …

Optimization Of Biomathematical Model Predictions For Cognitive Performance Impairment In Individuals: Accounting For Unknown Traits And Uncertain States In Homeostatic And Circadian Processes, Hans P. A. Van Dongen, Christopher G. Mott, Jen-Kuang Huang, Daniel J. Mollicone, Frederic D. Mckenzie, David F. Dinges

Mechanical & Aerospace Engineering Faculty Publications

Current biomathematical models of fatigue and performance do not accurately predict cognitive performance for individuals with a priori unknown degrees of trait vulnerability to sleep loss, do not predict performance reliably when initial conditions are uncertain, and do not yield statistically valid estimates of prediction accuracy, These limitations diminish their usefulness for predicting the performance of individuals in operational environments. To overcome these 3 limitations, a novel modeling approach was developed, based on the expansion of a statistical technique called Bayesian forecasting. The expanded Bayesian forecasting procedure was implemented in the two-process model of sleep regulation, which has been used …

Confidence Intervals For Individualized Performance Models, Hans P. A. Van Dongen, Christopher G. Mott, Jen-Kuang Huang, Daniel J. Millicone, Frederic D. Mckenzie, David F. Dinges

Mechanical & Aerospace Engineering Faculty Publications

Commentary on Reifman J; Rajaraman S; Gribok AV. Moving Towards Individualized Performance Models. Sleep 2007;30(9):1081-82.

On A Multinational Assessment Of Rotavirus Disease In Europe, David O. Matson

Community & Environmental Health Faculty Publications

Rotaviruses were discovered in the 1960s in animals and in the 1970s in humans; the latter discovery was made by an intrepid group who performed duodenal biopsies on children with acute gastroenteritis (AGE) [1]. By the late 1970s, data already clearly indicated that rotavirus was the cause of the annual winter peak of AGE affecting young children, as well as a frequent cause of severe gastroenteritis in various animal species (e.g., [2–5]). Use of the retrospectroscope clarified or left as tantalizing the suggestion that rotaviruses were the cause of the annual “winter vomiting syndrome” first described in children in 1910 …

Using Concentration Index To Study Changes In Socio-Economic Inequality Of Overweight Among Us Adolescents Between 1971 And 2002, Qi Zhang, Youfa Wang

Community & Environmental Health Faculty Publications

Background: The prevalence of overweight among adolescents continues to increase in the United States. This study examines the changes in socio-economic status (SES) inequality of overweight among US adolescents in the past three decades.

Methods: Concentration Index (CI) was utilized to measure changes in the SES inequality in prevalence of overweight among US adolescents. Data collected from 15286 adolescents in four waves of the National Health and Nutrition Examination Surveys (NHANES) between 1971 and 2002 and Hispanic Health and Nutrition Examination Survey (HHANES) (1982-84) were used.

Results: Changes in the SES inequality of overweight among US adolescents and considerable gender …

Potential For Stimulating Host Anti-Tumor Immune Response Via Rnai-Mediated Local Foxp3 Knockdown, N. Klaiber

Chemistry & Biochemistry Faculty Publications

Neoplastic growths represent a unique challenge for the host immune system. As they are indeed derived from self, many of the same mechanisms operating to prevent autoimmunity also provide an umbrella beneath which malignant cells are free to proliferate.1 Central among these immune regulatory boundaries are an influential subset of lymphocytes known as T regs. Hypothesized to exist decades ago, yet eluding definitive characterization until relatively recently, T regs have been demonstrated to play a crucial role in the proper functioning of the immune system as a whole. They may also, however, represent one of the primary obstacles to successful …

Teaching Parenting Skills In A Methadone Treatment Setting, Randy R. Gainey, Kevin P. Haggerty, Charles B. Fleming, Richard F. Catalano

Sociology & Criminal Justice Faculty Publications

Family factors significantly affect children’s risk of substance abuse, delinquency, and other problem behaviors (Arthur, Hawkins, Pollard, Catalano, & Baglioni, 2002). Children of substance abusers represent a particularly high-risk population. Prenatal exposure to addictive substances and the medical complications that may arise are important factors that, from conception, place this population at high risk of drug abuse and other problem behaviors (Griffith, Azuma, & Chasnoff, 1994). As children of substance abusers mature, their lives are characterized by exposure to continued drug and alcohol abuse by family members, recurrent or chronic illnesses, frequent moves, financial troubles, legal conflicts, family disorganization, and …

Bioelectric Effects Of Intense Nanosecond Pulses, Karl H. Schoenbach, Barbara Y. Hargrave, Ravindra P. Joshi, Juergen F. Kolb, Richard Nuccitelli, Christopher J. Osgood, Andrei G. Pakhomov, Michael W. Stacey, James R. Swanson, Jody A. White, Shu Xiao, Jue Zhang, Stephen J. Beebe, Peter F. Blackmore, E. Stephen Buescher

Bioelectrics Publications

Electrical models for biological cells predict that reducing the duration of applied electrical pulses to values below the charging time of the outer cell membrane (which is on the order of 100 ns for mammalian cells) causes a strong increase in the probability of electric field interactions with intracellular structures due to displacement currents. For electric field amplitudes exceeding MV/m, such pulses are also expected to allow access to the cell interior through conduction currents flowing through the permeabilized plasma membrane. In both cases, limiting the duration of the electrical pulses to nanoseconds ensures only nonthermal interactions of the electric …

Antimicrobial Mouthrinses In Contemporary Dental Hygiene Practice: The Take Home Message, Michele Leonardi Darby

Dental Hygiene Faculty Publications

The article discusses the significance of antimicrobial mouthrinses to the oral hygiene of people in the U.S. Such product is vital to those with or without dental problems because its regular use reduces supragingival plaque and gingivitis. Studies reveal that an American Dental Association (ADA)-Accepted antimicrobial mouthrinse can result in a greater reduction in plaque and gingivitis than brushing

Design, Synthesis, And Evaluation Of 10-N-Substituted Acridones As Novel Chemosensitizers In Plasmodium Falciparum, Jane X. Kelly, Martin J. Smilkstein, Roland A. Cooper, Kristin D. Lane, Robert A. Johnson, Aaron Janowsky, Rozalia A. Dodean, David J. Hinrichs, Rolf Winter, Michael Riscoe

Biological Sciences Faculty Publications

A series of novel 10-N-substituted acridones, bearing alkyl side chains with tertiary amine groups at the terminal position, were designed, synthesized, and evaluated for the ability to enhance the potency of quinoline drugs against multidrug-resistant (MDR) Plasmodium falciparum malaria parasites. A number of acridone derivatives, with side chains bridged three or more carbon atoms apart between the ring nitrogen and terminal nitrogen, demonstrated chloroquine (CQ)-chemosensitizing activity against the MDR strain of P. falciparum (Dd2). Isobolograrn analysis revealed that selected candidates demonstrated significant synergy with CQ in the CQ-resistant (CQR) parasite Dd2 but only additive (or indifferent) interaction in the CQ-sensitive …

Using Pareto Fronts To Evaluate Polyp Detection Algorithms For Ct Colonography, Adam Huang, Jiang Li, Ronald M. Summers, Nicholas Petrick, Amy K. Hara

Electrical & Computer Engineering Faculty Publications

We evaluate and improve an existing curvature-based region growing algorithm for colonic polyp detection for our CT colonography (CTC) computer-aided detection (CAD) system by using Pareto fronts. The performance of a polyp detection algorithm involves two conflicting objectives, minimizing both false negative (FN) and false positive (FP) detection rates. This problem does not produce a single optimal solution but a set of solutions known as a Pareto front. Any solution in a Pareto front can only outperform other solutions in one of the two competing objectives. Using evolutionary algorithms to find the Pareto fronts for multi-objective optimization problems has been …

Sir/Rsna/Cirse Joint Medical Simulation Task Force Strategic Plan: Executive Summary, Derek Gould, Aalpen Patel, Gary Becker, Buddy Conners, John Cardella, Steven Dawson, Craig Glaiberman, David Kessel, Mick Lee, Mark Scerbo

Psychology Faculty Publications

(First paragraph) The Executive Councils of the Society of Interventional Radiology (SIR), Radiological Society of North America (RSNA), and Cardiovascular and Interventional Radiological Society of Europe (CIRSE) have charged their Medical Simulation Task Forces and Work Groups to cooperate to achieve excellence and safety in interventional radiology patient care by jointly recommending and guiding implementation of a robust infrastructure and process to support Interventional Radiology (IR) simulation development, assessment, validation, application, and dissemination.

Exploration Of Computational Methods For Classification Of Movement Intention During Human Voluntary Movement From Single Trial Eeg, Ou Bai, Peter Lin, Sherry Vorbach, Jiang Li, Steve Furlani, Mark Hallett

Electrical & Computer Engineering Faculty Publications

Objective: To explore effective combinations of computational methods for the prediction of movement intention preceding the production of self-paced right and left hand movements from single trial scalp electroencephalogram (EEG).

Methods: Twelve naïve subjects performed self-paced movements consisting of three key strokes with either hand. EEG was recorded from 128 channels. The exploration was performed offline on single trial EEG data. We proposed that a successful computational procedure for classification would consist of spatial filtering, temporal filtering, feature selection, and pattern classification. A systematic investigation was performed with combinations of spatial filtering using principal component analysis (PCA), independent component analysis …

Validating Pareto Optimal Operation Parameters Of Polyp Detection Algorithms For Ct Colonography, Jiang Li, Adam Huang, Nicholas Petrick, Jianhua Yao, Ronald M. Summers, Maryellen L. Giger (Ed.), Nico Karssemeijer (Ed.)

Electrical & Computer Engineering Faculty Publications

We evaluated a Pareto front-based multi-objective evolutionary algorithm for optimizing our CT colonography (CTC) computer-aided detection (CAD) system. The system identifies colonic polyps based on curvature and volumetric based features, where a set of thresholds for these features was optimized by the evolutionary algorithm. We utilized a two-fold cross-validation (CV) method to test if the optimized thresholds can be generalized to new data sets. We performed the CV method on 133 patients; each patient had a prone and a supine scan. There were 103 colonoscopically confirmed polyps resulting in 188 positive detections in CTC reading from either the prone or …

Benchmarking Quality In Online Teaching And Learning: A Rubric For Course Construction And Evaluation, Mona P. Ternus, Kay L. Palmer, Debbie R. Faulk

Ellmer School of Nursing Faculty Publications

Online courses have many components and dimensions. Both the form (structure) and the content (expression) are situated in an overall environment. The sum of these elements results in student outcomes and learning. In order to facilitate construction and evaluate the quality of an online course, a four-part rubric was designed to reflect:

Structure (Context, Organization, and Environment)

Content (Presentation of Information)

Processes (Relationships and Interactions)

Outcomes (Mastery of Content and Course Evaluation)

This rubric was designed to provide quantitative and qualitative standardized evaluation for faculty self-evaluation, peer evaluation, and administrator evaluation. The rubric was piloted at two universities and shown …

The Impact Of Stress Management On Nurse Productivity And Retention, Tammi F. Milliken, Paul T. Clements, Harry J. Tillman

Counseling & Human Services Faculty Publications

Throughout the history of nursing there is a seeming legacy of personnel shortage, lack of funds, and, based on the nature of the role and related services, heightened levels of stress involved in patient care.

The future of the profession and more imminently, patient care and the health of nurses, may be significantly impacted by repeated challenges where current levels of stress and burnout are contributing to organizational problems, burnout, and attrition.

Employee stress and burn out commonly lead to myriad health-related problems that result in significant organizational consequences.

There are many methods of stress management, and sometimes the best …

An Art Therapy Intervention To Help Military Children Cope With Parental Deployment, Eleanor Kai Lampell

EVMS School of Health Professions Theses & Dissertations

Research regarding military children and their ability to cope with parental deployment is extensive. However, research dealing with art therapy and military children is limited. The purpose of this study was to explore the benefits of participating in group art therapy interventions for military children with a parent currently on deployment. Five group art therapy sessions were conducted with two military children with a parent currently in stage two of parental deployment. It was hypothesized that through participating in group art therapy, military children with a parent who is currently deployed would have a reduction of problematic behaviors in a …

Dietary Supplements And Sports Performance: Metabolites, Constituents, And Extracts, Melvin H. Williams

Human Movement Studies & Special Education Faculty Publications

This is the fifth in a series of six articles to discuss the major classes of dietary supplements ( vitamins; minerals; amino acids; herbs or botanicals; and metabolites/constituents/extracts). The major focus is on efficacy of such dietary supplements to enhance exercise or sports performance.