Medicine and Health Sciences Commons^™

Perspective Paper: Assessing Air Quality As Part Of A Physical Therapy Plan Of Care, Dennis Sobush, Monika Burrescia

Physical Therapy Faculty Research and Publications

Purpose: The purposes of this clinical perspective paper are (1) to expand physical therapists’ awareness to the topic of air quality as a health priority when providing professional services; and (2) to provide templates for screening the indoor clinical environments and patient profiles to avert respiratory exacerbations, especially in persons with asthma. Summary of Key Points: The location where a physical therapist practices determines the air quality indices to which a person is exposed. Poor indoor air quality can expose a person to even greater compromise of respiration (ie, Sick Building Syndrome) than outdoor air quality secondary to an array …

Repeated N-Acetyl Cysteine Reduces Cocaine Seeking In Rodents And Craving In Cocaine-Dependent Humans, Shelley L. Amen, Linda B. Piacentine, Muhammad E. Ahmad, Shi-Jiang Li, John R. Mantsch, Robert C. Risinger, David A. Baker

Biomedical Sciences Faculty Research and Publications

Addiction is a chronic relapsing disorder hypothesized to be produced by drug-induced plasticity that renders individuals vulnerable to craving-inducing stimuli such as re-exposure to the drug of abuse. Drug-induced plasticity that may result in the addiction phenotype includes increased excitatory signaling within corticostriatal pathways that correlates with craving in humans and is necessary for reinstatement in rodents. Reduced cystine–glutamate exchange by system x_c– appears to contribute to heightened excitatory signaling within the striatum, thereby posing this as a novel target in the treatment of addiction. In the present report, we examined the impact of repeated N-acetyl cysteine, …

Adrenal Activity During Repeated Long-Access Cocaine Self-Administration Is Required For Later Crf-Induced And Crf-Dependent Stressor-Induced Reinstatement In Rats, Evan N. Graf, Michael A. Hoks, Jean Baumgardner, Jose Sierra, Oliver Vranjkovic, Colin Bohr, David A. Baker, John R. Mantsch

Biomedical Sciences Faculty Research and Publications

Understanding the neurobiological processes that contribute to the establishment and expression of stress-induced regulation of cocaine use in addicted individuals is important for the development of new and better treatment approaches. It has been previously shown that rats self-administering cocaine under long-access conditions (6 h daily) display heightened susceptibility to the reinstatement of extinguished cocaine seeking by a stressor, electric footshock, or i.c.v. administration of the stressor-responsive neuropeptide, corticotropin-releasing factor (CRF). This study tested the hypothesis that adrenal responsiveness during earlier long-access cocaine self-administration (SA) is necessary for the establishment of later CRF-dependent stress-induced reinstatement. Reinstatement by footshock, but not …

Outcomes And Cost Analysis Of The Impact Of Unit-Level Nurse Staffing On Post-Discharge Utilization, Kathleen Bobay, Olga Yakusheva, Marianne E. Weiss

College of Nursing Faculty Research and Publications

No abstract provided.

Peer Effects And The Freshman 15: Evidence From A Natural Experiment, Olga Yakusheva, Kandice A. Kapinos, Marianne E. Weiss

College of Nursing Faculty Research and Publications

This study investigates the importance of peer effects in explaining weight gain among freshman college students. We exploit a natural experiment that takes place on most college campuses in the US - randomized roommate assignments. While previous studies suggest that having an obese spouse, friend, or sibling increases one's likelihood of becoming obese, these social interactions are clearly non-random. We collect data from female students living on campus at a private Midwestern university at the beginning and end of their first year of college. Our findings suggest that the amount of weight gained during the freshman year is strongly and …

The Effects Of A Closed-Chain, Eccentric Training Program On Hamstring Injuries Of A Professional Football Cheerleading Team, Jay S. Greenstein, Barton N. Bishop, Jean S. Edward, Robert V. Topp

College of Nursing Faculty Research and Publications

Objective

Hamstring injuries are a common occurrence among professional football cheerleaders. The purpose of this study is to identify the effects of an eccentric, closed-chain hamstring exercise intervention on hamstring injury–associated pain during the course of the football season among professional football cheerleaders.

Methods

Forty-three female cheerleaders participated in an eccentric, closed-chain hamstring exercise intervention protocol provided by doctors of chiropractic that incorporated loops of elastic-band or Thera-Band Loops (Hygenic Corporation, Akron, OH) during practice and at home during the regular football season. Hamstring injury–related pain was assessed in June, during team selection; in September, at the start of the …

Association Between The Female Athlete Triad And Endothelial Dysfunction In Dancers, Anne Z. Hoch, Paula E. Papanek, Aniko Szabo, Michael E. Widlansky, Jane E. Schimke, David D. Gutterman

Exercise Science Faculty Research and Publications

Objective: To determine the prevalence of the 3 components of the female athlete triad [disordered eating, menstrual dysfunction, low bone mineral density (BMD)] and their relationships with brachial artery flow-mediated dilation in professional dancers.

Design: Prospective study.

Setting: Academic institution in the Midwest.

Participants: Twenty-two professional ballet dancers volunteered for this study.

Interventions: The prevalence of the female athlete triad and its relationship to endothelial dysfunction.

Main Outcome Measures: Subjects completed questionnaires to assess disordered eating and menstrual status/history. They also completed a 3-day food record and wore an accelerometer for 3 days to …

Myocardial Dysfunction In An Animal Model Of Cancer Cachexia, Hui Xu, Danielle Crawford, Kirk R. Hutchinson, Dane J. Youtz, Pamela A. Lucchesi, Markus Velten, Donna O. Mccarthy, Loren E. Wold

College of Nursing Faculty Research and Publications

Aims

Fatigue is a common occurrence in cancer patients regardless of tumor type or anti-tumor therapies and is an especially problematic symptom in persons with incurable tumor disease. In rodents, tumor-induced fatigue is associated with a progressive loss of skeletal muscle mass and increased expression of biomarkers of muscle protein degradation. The purpose of the present study was to determine if muscle wasting and expression of biomarkers of muscle protein degradation occur in the hearts of tumor-bearing mice, and if these effects of tumor growth are associated with changes in cardiac function.

Main methods

The colon26 adenocarcinoma cell line was …

The Effects Of Lesions In The Dorsolateral Pons On The Coordination Of Swallowing And Breathing In Awake Goats, Joshua M. Bonis, S. E. Neumueller, B. D. Marshall, K. L. Krause, B. Qian, Lawrence Pan, M. R. Hodges, Hubert V. Forster

Physical Therapy Faculty Research and Publications

The purpose of this retrospective study was to gain insight into the contribution of the dorsolateral pons to the coordination of swallowing and breathing in awake goats. In 4 goats, cannulas were chronically implanted bilaterally through the lateral (LPBN) and medial (MPBN) parabrachial nuclei just dorsal to the Kölliker–Fuse nucleus (KFN). After >2 weeks recovery from this surgery, the goats were studied for 5½ h on a control day, and on separate days after receiving 1 and 10 μl injections of ibotenic acid (IA) separated by 1 week. The frequency of swallows did not change during the control and 1 …

Characteristics Of The Menstrual Cycle After Discontinuation Of Oral Contraceptives, Claudia L. Nassaralla, Joseph B. Stanford, Diane Daly, Mary Schneider, Karen C. Schliep, Richard J. Fehring

College of Nursing Faculty Research and Publications

Background: Menstrual cycle function may continue to be altered after discontinuation of oral contraceptives (OC). Few studies have been published on the effects of recent OC use on menstrual cycle parameters; none have examined characteristics of the menstrual flow or the quality of cervical mucus. The purpose of this retrospective matched cohort study is to assess biomarkers of the menstrual cycle after discontinuation of OCs.

Methods: Among a sample of women who daily recorded observations of menstrual cycle biomarkers, 70 women who had recently discontinued OCs were randomly matched by age and parity with 70 women who had …

Promoting Natural Family Planning, Richard J. Fehring

College of Nursing Faculty Research and Publications

No abstract provided.

Apoptosis In Displaced Temporomandibular Joint Disc With And Without Reduction: An Immunohistochemical Study, Carla Loreto, Luis Eduardo Almeida, Paula C. Trevilatto, Rosalia Leonardi

School of Dentistry Faculty Research and Publications

Internal derangement (ID) of the temporomandibular joint (TMJ) is due to an abnormal relationship of the articular disc to the mandibular condyle, glenoid fossa and articular eminence. The two most common types of internal derangement are anterior disc displacement with (ADDwR) and without reduction (ADDwoR). Disc displacement is associated with degenerative tissue changes. The histological features of discs from patients with TMJ ID reflect a general remodelling caused by abnormal loading. A correlation has been demonstrated between TMJ ID and apoptosis. Few investigations have addressed the role of apoptosis or caspase activity in TMJ ID. The apoptosis activation process was …

Covariation Among Vowel Height Effects On Acoustic Measures, Jeffrey J. Berry, Maura Jones Moyle

Speech Pathology and Audiology Faculty Research and Publications

Covariation among vowel height effects on vowel intrinsic fundamental frequency (IF0), voice onset time (VOT), and voiceless interval duration (VID) is analyzed to assess the plausibility of a common physiological mechanism underlying variation in these measures. Phrases spoken by 20 young adults, containing words composed of initial voiceless stops or /s/ and high or low vowels, were produced in habitual and voluntarily increased F0 conditions. High vowels were associated with increased IF0 and longer VIDs. VOT and VID exhibited significant covariation with IF0 only for males at habitual

The Effect Of High Dose Total Body Irradiation On Acth, Corticosterone, And Catecholamines In The Rat, Eric P. Cohen, Eric D. Bruder, William E. Cullinan, Dana R. Ziegler, Hershel Raff

Biomedical Sciences Faculty Research and Publications

Total body irradiation (TBI) or partial body irradiation is a distinct risk of accidental, wartime, or terrorist events. Total body irradiation is also used as conditioning therapy before hematopoietic stem cell transplantation. This therapy can result in injury to multiple tissues and might result in death as a result of multiorgan failure. The hypothalamic–pituitary–adrenal (HPA) axis could play a causative role in those injuries, in addition to being activated under conditions of stress. In a rat model of TBI, we have established that radiation nephropathy is a significant lethal complication, which is caused by hypertension and uremia. The current study …

Psychometric Testing Of The Children's Resourcefulness Scale, Jaclene A. Zauszniewski, Abir K. Bekhet, Elizabeth Bonham

College of Nursing Faculty Research and Publications

PROBLEM: Resourcefulness is known to reduce depression in adults, but its effects on children are less well known, possibly for lack of a psychometrically sound measure.

METHODS: This study examined the reliability and validity of the 32-item Children's Self-Control Scale (C-SCS), which measures resourcefulness, in 122 school-aged children.

FINDINGS: Standard scale refinement methods produced a 10-item scale with α = .72 and correlations with the C-SCS (r = .86), positive thoughts (r = .38), and depressive symptoms (r = –.32). Factor analysis revealed two factors: problem-solving and delay of gratification.

CONCLUSIONS: The 10-item scale may be …

Advancing Nursing Education Science: An Analysis Of Nln's Grant Program 2008-2010, Joanne R. Duffy, Marilyn Frenn, Barbara Patterson

College of Nursing Faculty Research and Publications

The National League for Nursing has responded to the increasing need for nursing education research through its grant program. Significant growth in proposals has intensified competition for funds and challenged the Nursing Education Research Advisory Council’s review process. The purpose of this article is to explore the NLN’s nursing education research proposals from 2008 to 2010 in order to improve performance and provide guidance to future nursing education researchers. Beginning with the 2008 grant cycle, a database was developed to assist in performance improvement. A total of 113 proposals were submitted; of those, 24 were funded for a success rate …

Dog Models Of Naturally Occurring Cancer, Donna O. Mccarthy

College of Nursing Faculty Research and Publications

Studies using dogs provide an ideal solution to the gap in animal models for natural disease and translational medicine. This is evidenced by approximately 400 inherited disorders being characterized in domesticated dogs, most of which are relevant to humans. There are several hundred isolated populations of dogs (breeds) and each has a vastly reduced genetic variation compared with humans; this simplifies disease mapping and pharmacogenomics. Dogs age five- to eight-fold faster than do humans, share environments with their owners, are usually kept until old age and receive a high level of health care. Farseeing investigators recognized this potential and, over …

Analysis Of Knee Flexion Angles During 2 Clinical Versions Of The Heel Raise Test To Assess Soleus And Gastrocnemius Function, Kim Hébert-Losier, Anthony G. Schneiders, S John Sullivan, Richard J. Newsham-West, José A. García, Guy G. Simoneau

Physical Therapy Faculty Research and Publications

STUDY DESIGN: Controlled laboratory study, using a repeated-measures, counterbalanced design. OBJECTIVES: To provide estimates on the average knee angle maintained, absolute knee angle error, and total repetitions performed during 2 versions of the heel raise test. BACKGROUND: The heel raise test is performed in knee extension (EHRT) to assess gastrocnemius and knee flexion (FHRT) for soleus. However, it has not yet been determined whether select knee angles are maintained or whether total repetitions differ between the clinical versions of the heel raise test. METHODS: Seventeen healthy males and females performed maximal heel raise repetitions in 0° (EHRT) and 30° (FHRT) …

Access To Adequate Outpatient Depression Care For Mothers In The Usa: A Nationally Representative Population-Based Study, Whitney P. Witt, Abiola O. Keller, Carrisa Gottlieb, Kristin Litzelman, John Hampton, Jonathan Maguire, Erika W. Hagen

College of Nursing Faculty Research and Publications

Maternal depression is often untreated, resulting in serious consequences for mothers and their children. Factors associated with receipt of adequate treatment for depression were examined in a population-based sample of 2,130 mothers in the USA with depression using data from the 1996–2005 Medical Expenditure Panel Survey. Chi-squared analyses were used to evaluate differences in sociodemographic and health characteristics by maternal depression treatment status (none, some, and adequate). Multivariate regression was used to model the odds of receiving some or adequate treatment, compared to none. Results indicated that only 34.8% of mothers in the USA with depression received adequate treatment. Mothers …

The Influence Of Contraception On Abortion Among Women Of Reproductive Age In The United States, Richard J. Fehring

College of Nursing Faculty Research and Publications

There is a common notion that contraception is necessary for women (and couples) to avoid unwanted pregnancies and abortions. The thesis of this paper is that contraception actually will lead to more (not less) abortions. On the other hand, the use of natural family planning (NFP) and the acceptance of fertility lend itself to the openness to life. The specific purpose of the paper is to describe the influence of contraceptive use and NFP on the likelihood of having an abortion among United States (US) women of reproductive age as found in Cycle 7 of the National Survey of Family …

Factors Predicting Physical Activity Among Older Thais Living In Low Socioeconomic Urban Communities, Phachongchit Kraithaworn, Yupapin Sirapo-Ngam, Noppawan Piaseu, Dechavudh Nityasuddhi, Kimberlee A. Gretebeck

College of Nursing Faculty Research and Publications

This study was conducted to determine if specific factors (physical activity self-efficacy, sense of community, social support, perceived physical and mental health, and neighborhood environment and facilities) predicted physical activity among 258 older Thais living in six registered, low-socioeconomic, urban communities across metropolitan Bangkok. The theoretical model was based on integrated concepts from Pender’s Health Promotion Model and the Social Ecological Model. The hypothesized model was tested using path analysis.

The final model explained 33%, 51% and 22% of the variance in physical activity, physical activity self-efficacy and sense of community, respectively. Physical activity self-efficacy was the most powerful predictor …

Prediction Of Vo2 Peak Using Sub-Maximum Bench Step Test In Children, Robert V. Topp, Dean E. Jacks, Justin B. Moore

College of Nursing Faculty Research and Publications

The purpose of this study was to develop a valid prediction of maximal oxygen uptake from data collected during a submaximum bench stepping test among children ages 8-12 years. Twenty seven active subjects (16 male and 11 female), weight 36.1 kg, height 144.4 cm and VO₂ 47.4 ± 7.9 ml/kg/min participated. Subjects completed a maximal oxygen consumption test with analysis of expired air and a submaximal bench stepping test. A formula to predict VO_2max was developed from height, resting heart rate and heart rate response during the submaximum bench stepping test. This formula accounted for 71% of the …

The Effects Of Positive Cognitions On The Relationship Between Alienation And Resourcefulness In Nursing Students In Egypt, Abir K. Bekhet, Mervat Elguenidi, Jaclene A. Zauszniewski

College of Nursing Faculty Research and Publications

Alienation is a subjective state, a feeling of being a stranger, as if one were not one's normal self. It is also a sense of homelessness; a feeling of uneasiness or discomfort, which signifies the person's exclusion from social or cultural participation. Alienation can adversely affect healthy functioning of nursing students. Nursing students are the adolescents of today and the nurses of tomorrow who will deal with human behavior, and their psychological well-being will be important in managing their clients’ conditions. Healthy nursing students are likely to become healthy nurses who can then model and promote healthy lifestyles for their …

Effects Of Resistance Training On Functional Ability In Elderly Individuals, Mariane M. Fahlman, Nancy Mcnevin, Debra Boardley, Amy Morgan, Robert V. Topp

College of Nursing Faculty Research and Publications

Purpose. Determine the effects of 16 weeks of strength training on measures of functional ability in elderly who are functionally limited.

Design. Quasi-experimental trial in which elderly volunteers were assigned to either an exercise group or a control group.

Participants. Eighty-seven participants (65–93 years) living independently but with some functional limitations.

Intervention. Thirteen different strength training exercises using Thera-Band resistive bands (Hygenic Corporation, Akron, Ohio). The program was 16 weeks in duration, and the frequency was three times per week. Participants exercised in a group setting one time per week and were given a home exercise book to follow for …

Psychometric Properties Of The Pressure To Move Scale In Relocated American Older Adults: Further Evaluation, Abir K. Bekhet, Jaclene Zauszniewski, Wagdy E. Nakhla

College of Nursing Faculty Research and Publications

The number of elders who relocate to retirement communities is increasing exponentially, and their ability to exercise free choice, personal control, and autonomy has been associated with relocation adjustment and positive outcomes in regard to physical, emotional, and social well-being. Although a measure of relocation controllability (the degree of personal control associated with the move) exists, there is limited evidence of its psychometric adequacy. This study tested the reliability and validity of the Pressure to Move Scale (PTMS). A convenience sample of 104 American elders who relocated to six Northeast Ohio retirement communities was recruited. Study participants completed the nine-item …

Psychometric Properties Of A Measure Of Acceptance Of Long-Standing Health Problems, Patricia Mcdonald, Jaclene Zauszniewski, Abir K. Bekhet

College of Nursing Faculty Research and Publications

Acceptance of chronic illness is important for health promotion and for improving the quality of life of elders with chronic conditions. Thus, a reliable and valid measure of acceptance is needed for this population. Currently available measures of acceptance do not focus specifically on accepting chronic conditions. This study of 176 elders with chronic conditions examined the psychometric properties of an adapted measure of acceptance—the Ideas About Long-Standing Health Problems (IALHP) questionnaire. Although the findings provided beginning evidence for internal reliability and construct validity to support its potential usefulness in elders, further scale development is recommended.

Measuring Use Of Resourcefulness Skills: Psychometric Testing Of A New Scale, Abir K. Bekhet

College of Nursing Faculty Research and Publications

Highly resourceful individuals have been found better able to meet life's challenges and to experience more positive health outcomes. Although psychometrically sound measures of resourcefulness exist and resourcefulness training trials show that the intervention increases adaptive functioning and enhances quality of life, there is no direct measure of intervention fidelity. This study examined the reliability and validity of an 8-item Resourcefulness Skills Scale (RSS), which measures the frequency with which intervention recipients use specific resourcefulness skills. The RSS was found to have acceptable internal consistency (� = .78), criterion-related validity (�'s = .50 and .52 with other resourcefulness scales), and …

Resilient Observer Design For Discrete-Time Nonlinear Systems With General Criteria, Chung Seop Jeong, Edwin E. Yaz, Yvonne I. Yaz

Exercise Science Faculty Research and Publications

A class of discrete-time nonlinear system and measurement equations having incrementally conic nonlinearities and finite energy disturbances is considered. A linear matrix inequality based resilient observer design approach is presented to guarantee the satisfaction of a variety of performance criteria ranging from simple estimation error boundedness to dissipativity in the presence of bounded perturbations on the gain. Some simulation examples are included to illustrate the proposed design methodology.

Pain Perception After Isometric Exercise In Women With Fibromyalgia, Marie K. Hoeger Bement, Andy Weyer, Sarah Hartley, Breanna Drewek, April L. Harkins, Sandra K. Hunter

Exercise Science Faculty Research and Publications

Objective: The purpose of this study was to identify exercise protocols incorporating isometric contractions that provide pain relief in women with fibromyalgia.

Design: A before-after trial.

Setting: A physical therapy department in an academic setting.

Participants: Fifteen women (mean ± SD, 52 ± 11y) with fibromyalgia.

Interventions: Subjects completed 4 sessions: 1 familiarization and 3 experimental. The following randomized experimental sessions involved the performance of isometric contractions with the elbow flexor muscles that varied in intensity and duration: (1) 3 maximal voluntary contractions (MVCs), (2) 25% MVC held to task failure, and (3) 25% MVC …

New Phosphated Poly(Methyl Methacrylate) Polymers For The Prevention Of Denture-Induced Microbial Infection: An In Vitro Study, Antony Raj, Andrew R. Dentino

School of Dentistry Faculty Research and Publications

Purpose: Poly(methyl methacrylate) (PMMA) has been widely used as a denture-base acrylic resin due to its excellent physical and mechanical properties. However, the material is highly prone to microbial fouling that often leads to Candida-associated denture stomatitis. Incorporation of phosphate groups into PMMA could facilitate adsorption of salivary antimicrobials and inhibit microbial adherence on the polymer surface. An in vitro study evaluated PMMA polymers containing varying amounts of phosphate group for their efficacy to inhibit Candida albicans adhesion, adsorb salivary histatin 5, and exhibit candidacidal activity.

Methods: Six PMMA polymers containing 0%, 5%, 15%, 10%, 20%, and 25% of …