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Articles 1741 - 1770 of 3247
Full-Text Articles in Medicine and Health Sciences
A Theater Intervention To Prevent Teen Dating Violence For Mexican-American Middle School Students, Ruth Ann Belknap, Kristin Haglund, Holly Felzer, Jessica E. Pruszynski, John Schneider
A Theater Intervention To Prevent Teen Dating Violence For Mexican-American Middle School Students, Ruth Ann Belknap, Kristin Haglund, Holly Felzer, Jessica E. Pruszynski, John Schneider
College of Nursing Faculty Research and Publications
Purpose
To test a theater intervention designed to raise awareness of the dynamics and consequences of teen dating violence (TDV) and to facilitate creation of nonviolent responses to TDV among Latino and Latina adolescents. The intervention was based on Theater of the Oppressed, which advocates the use of theater methods to explore social issues and to allow audiences to experiment with problem-solving, thereby promoting change.
Methods
This study used a pretest–posttest, no control group, mixed-measures design to study 66 Mexican-American adolescents (mean age, 13.4 ± 5 years). Two plays containing subtle and overt signs of control and abuse were written …
Randomized Comparison Of Two Internet-Supported Fertility Awareness Based Methods Of Family Planning, Richard J. Fehring, Mary Schneider, Kathleen Raviele, Dana Rodriguez, Jessica E. Pruszynski
Randomized Comparison Of Two Internet-Supported Fertility Awareness Based Methods Of Family Planning, Richard J. Fehring, Mary Schneider, Kathleen Raviele, Dana Rodriguez, Jessica E. Pruszynski
College of Nursing Faculty Research and Publications
Background
The aim was to compare the efficacy and acceptability of two Internet-supported fertility-awareness-based methods of family planning.
Study design
Six hundred and sixty-seven women and their male partners were randomized into either an electronic hormonal fertility monitor (EHFM) group or a cervical mucus monitoring (CMM) group. Both groups utilized a Web site with instructions, charts and support. Acceptability was assessed online at 1, 3 and 6 months. Pregnancy rates were determined by survival analysis.
Results
The EHFM participants (N= 197) had a total pregnancy rate of 7 per 100 users over 12 months of use compared with …
Spirituality, Religiosity, Depression, Anxiety, And Drug-Use Consequences During Methadone Maintenance Therapy, Linda B. Piacentine
Spirituality, Religiosity, Depression, Anxiety, And Drug-Use Consequences During Methadone Maintenance Therapy, Linda B. Piacentine
College of Nursing Faculty Research and Publications
Substance addiction is damaging to the health of persons, families, and society. Often the person with addiction has decreased spirituality and religiosity and suffers from anxiety, depression, or both, increasing the risk for continued substance use and its concomitant negative consequences. The study purpose was to describe spirituality and religiosity, among persons enrolled in methadone maintenance therapy and to examine associations between spirituality, religiosity, anxiety, depression, and drug-use consequences. Using a descriptive and cross-sectional correlational design, 108 participants completed questionnaires assessing the study variables. Spiritual well-being was similar to other addiction samples and lower than healthy person samples. Most participants …
Racial And Ethnic Variations In Waiting Times For Emergency Department Visits Related To Nontraumatic Dental Conditions In The United States, Christopher Okunseri, Elaye Okunseri, Cesar A. Chilmaza, Shazeen Harunani, Qun Xiang, Aniko Szabo
Racial And Ethnic Variations In Waiting Times For Emergency Department Visits Related To Nontraumatic Dental Conditions In The United States, Christopher Okunseri, Elaye Okunseri, Cesar A. Chilmaza, Shazeen Harunani, Qun Xiang, Aniko Szabo
School of Dentistry Faculty Research and Publications
Background
Researchers have documented an association between waiting times in emergency departments (EDs) and quality of care for medical conditions, but little is known about trends and factors associated with waiting times for ED visits related to nontraumatic dental conditions (NTDCs). The authors examined trends in waiting time and associated factors for NTDC-related ED visits in the United States.
Methods
The authors analyzed data from the National Hospital Ambulatory Medical Care survey for 1997 to 2007, excluding 2001 and 2002 owing to lack of information about waiting times. The authors used a survey-weighted linear regression of log-transformed waiting-time model to …
Prefrontal Activity Links Nonoverlapping Events In Memory, Marieke R. Gilmartin, Hiroyuki Miyawaki, Fred J. Helmstetter, Kamran Diba
Prefrontal Activity Links Nonoverlapping Events In Memory, Marieke R. Gilmartin, Hiroyuki Miyawaki, Fred J. Helmstetter, Kamran Diba
Biomedical Sciences Faculty Research and Publications
The medial prefrontal cortex (mPFC) plays an important role in memory. By maintaining a working memory buffer, neurons in prelimbic (PL) mPFC may selectively contribute to learning associations between stimuli that are separated in time, as in trace fear conditioning (TFC). Until now, evidence for this bridging role was largely descriptive. Here we used optogenetics to silence neurons in the PL mPFC of rats during learning in TFC. Memory formation was prevented when mPFC was silenced specifically during the interval separating the cue and shock. Our results provide support for a working memory function for these cells and indicate that …
Has The Foundation For Physical Therapy Advanced The Body Of Knowledge?, Sheila Schindler-Ivens, Jan Struhar, Martha G. Jermé
Has The Foundation For Physical Therapy Advanced The Body Of Knowledge?, Sheila Schindler-Ivens, Jan Struhar, Martha G. Jermé
Physical Therapy Faculty Research and Publications
No abstract provided.
Quality Improvement Project: Analysis Of Efficiency Of Current Order Set For The Diagnostic Workup Used To Evaluate Neurogenic Stress Myocardium In Aneurysmal Subarachnoid Hemorrhage, Denise Miller Niklasch, Kathleen Bobay
Quality Improvement Project: Analysis Of Efficiency Of Current Order Set For The Diagnostic Workup Used To Evaluate Neurogenic Stress Myocardium In Aneurysmal Subarachnoid Hemorrhage, Denise Miller Niklasch, Kathleen Bobay
College of Nursing Faculty Research and Publications
Purpose
To evaluate patterns of utilization of the aneurysmal subarachnoid hemorrhage (aSAH) protocol order set for neurogenic stress myocardium (NSM).
Data sources
Retrospective chart review.
Conclusions
The results of this study demonstrate that protocol order sets can be prone to omissions, variations in practice, and delays.
Implications for practice
Education and implementation of an intervening compliance monitor are essential to improve utilization and correctness in use of the aSAH protocol order set for NSM. Advance practice nurses (APNs) or nursing staff could provide this service. This would improve teamwork, improve efficiency of care delivery and utilization of resources, promote leadership …
Leisure-Time Physical Activity In Relation To Depressive Symptoms In African-Americans: Results From The National Survey Of American Life, Elisa R. Torres, Carolyn M. Sampselle, David L. Ronis, Harold W. Neighbors, Kimberlee A. Gretebeck
Leisure-Time Physical Activity In Relation To Depressive Symptoms In African-Americans: Results From The National Survey Of American Life, Elisa R. Torres, Carolyn M. Sampselle, David L. Ronis, Harold W. Neighbors, Kimberlee A. Gretebeck
College of Nursing Faculty Research and Publications
Objective
To examine the frequency of leisure-time physical activity (LTPA) in relation to depressive symptoms in a nationally representative sample of African American (AA) women and AA men with guidance by Stokols' Social Ecological Framework.
Method
A secondary analysis of AA women (n = 1811) and AA men (n = 1038) was performed on the National Survey of American Life, where a four stage national area probability sampling was conducted. Interviews were conducted 2001–2003. Clinically depressed AA were excluded from the current study. LTPA was measured by self-report frequency (never, rarely, sometimes, often) of participation in sports/exercise. Depressive symptoms were …
Children With Autism Spectrum Disorder At A Pediatric Hospital: A Systematic Review Of The Literature, Norah L. Johnson, Dana Rodriguez
Children With Autism Spectrum Disorder At A Pediatric Hospital: A Systematic Review Of The Literature, Norah L. Johnson, Dana Rodriguez
College of Nursing Faculty Research and Publications
This review of literature describes the behaviors of hospitalized children with autism spectrum disorder (ASD) that health care providers find challenging. It also identifies strategies used to address these challenging behaviors. The systematic review of literature identified 34 articles from databases on health care of challenging behaviors of children with ASD. The review identified four categories of challenging behaviors (non-compliance, hyperactivity, sensory defensiveness, self-injury) and several strategies for reducing these behaviors. Partnering with parents to develop strategies is important for children with ASD to deliver timely and safe care.
Differences In Kinematic Control Of Ankle Joint Motions In People With Chronic Ankle Instability, Kristof Kipp, Rianna M. Palmieri-Smith
Differences In Kinematic Control Of Ankle Joint Motions In People With Chronic Ankle Instability, Kristof Kipp, Rianna M. Palmieri-Smith
Exercise Science Faculty Research and Publications
Background
People with chronic ankle instability display different ankle joint motions compared to healthy people. The purpose of this study was to investigate the strategies used to control ankle joint motions between a group of people with chronic ankle instability and a group of healthy, matched controls.
Methods
Kinematic data were collected from 11 people with chronic ankle instability and 11 matched control subjects as they performed a single-leg land-and-cut maneuver. Three-dimensional ankle joint angles were calculated from 100 ms before, to 200 ms after landing. Kinematic control of the three rotational ankle joint degrees of freedom was investigated by …
Nr2a- And Nr2b-Containing Nmda Receptors In The Prelimbic Medial Prefrontal Cortex Differentially Mediate Trace, Delay, And Contextual Fear Conditioning, Marieke R. Gilmartin, Janine L. Kwapis, Fred J. Helmstetter
Nr2a- And Nr2b-Containing Nmda Receptors In The Prelimbic Medial Prefrontal Cortex Differentially Mediate Trace, Delay, And Contextual Fear Conditioning, Marieke R. Gilmartin, Janine L. Kwapis, Fred J. Helmstetter
Biomedical Sciences Faculty Research and Publications
Activation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association. The NR2B subunit confers unique properties to the NMDAR and may differentially regulate these two fear memories. Here we show that NR2A-containing NMDARs mediate trace, delay, and contextual fear memories, but NR2B-containing NMDARs are required only for trace conditioning, consistent with a role for PL mPFC in working memory.
Oral Atypical Cellular Blue Nevus: An Infiltrative Melanocytic Proliferation, Brian S. Shumway, Yeshwant B. Rawal, Carl M. Allen, John R. Kalmar, Cynthia M. Magro
Oral Atypical Cellular Blue Nevus: An Infiltrative Melanocytic Proliferation, Brian S. Shumway, Yeshwant B. Rawal, Carl M. Allen, John R. Kalmar, Cynthia M. Magro
School of Dentistry Faculty Research and Publications
The atypical cellular blue nevus is an extremely rare nevomelanocytic lesion which lacks precise histologic characterization in the current literature. Given the potential for significant architectural and cytologic overlap with melanoma, further study, including molecular analysis, is needed. This is the first description of an atypical cellular blue nevus of the oral cavity.
Effects Of Patient-Directed Music Intervention On Anxiety And Sedative Exposure In Critically Ill Patients Receiving Mechanical Ventilatory Support: A Randomized Clinical Trial, Jill L. Guttormson, Linda L. Chlan, Craig R. Weinert, Annie Heiderscheidt, Mary Fran Tracy, Debra J. Skaar, Kay Savik
Effects Of Patient-Directed Music Intervention On Anxiety And Sedative Exposure In Critically Ill Patients Receiving Mechanical Ventilatory Support: A Randomized Clinical Trial, Jill L. Guttormson, Linda L. Chlan, Craig R. Weinert, Annie Heiderscheidt, Mary Fran Tracy, Debra J. Skaar, Kay Savik
College of Nursing Faculty Research and Publications
Importance: Alternatives to sedative medications, such as music, may alleviate the anxiety associated with ventilatory support.
Objective: To test whether listening to self-initiated patient-directed music (PDM) can reduce anxiety and sedative exposure during ventilatory support in critically ill patients.
Design, Setting, and Patients: Randomized clinical trial that enrolled 373 patients from 12 intensive care units (ICUs) at 5 hospitals in the Minneapolis-St Paul, Minnesota, area receiving acute mechanical ventilatory support for respiratory failure between September 2006 and March 2011. Of the patients included in the study, 86% were white, 52% were female, and the mean (SD) age was …
Evidence For Covalent Linkage Between Some Plasma Α2-Antiplasmin Molecules And Aα Chains Of Circulating Fibrinogen, Michael W. Mosesson, Trudy Holyst, Irene Hernandez, Kevin R. Siebenlist
Evidence For Covalent Linkage Between Some Plasma Α2-Antiplasmin Molecules And Aα Chains Of Circulating Fibrinogen, Michael W. Mosesson, Trudy Holyst, Irene Hernandez, Kevin R. Siebenlist
Biomedical Sciences Faculty Research and Publications
Plasma alpha2-antiplasmin (α2AP) is a single-chain serine protease inhibitor acting mainly through the fibrinolytic system. Its physiological importance is underscored by the observation that homozygous α2AP deficiency results in a severe hemorrhagic disorder due to rapid fibrin clot lysis (hyperfibrinolysis).
Structured Debriefing And Students' Clinical Judgment Abilities In Simulation, Bette Mariani, Mary Ann Cantrell, Colleen H. Meakim, Patricia Prieto, Kristina Dreifuerst
Structured Debriefing And Students' Clinical Judgment Abilities In Simulation, Bette Mariani, Mary Ann Cantrell, Colleen H. Meakim, Patricia Prieto, Kristina Dreifuerst
College of Nursing Faculty Research and Publications
Background
Debriefing is a critical component of clinical simulation, yet there are limited studies that demonstrate the outcomes of debriefing on learners' clinical judgment.
Method
Using the Lasater Clinical Judgment Rubric, this mixed-method study examined the effects of structured debriefing after 2 clinical simulation experiences on 86 junior-level baccalaureate nursing students' clinical judgment. Debriefing for Meaningful Learning© was the method used for the structured debriefing sessions.
Results
The mean clinical judgment scores of the intervention group were higher and improved more over time compared with the mean scores of those in the control group; however, the differences were not statistically …
Nurse Residency Program: Best Practices For Optimizing Organizational Success, Marilyn Meyer Bratt
Nurse Residency Program: Best Practices For Optimizing Organizational Success, Marilyn Meyer Bratt
College of Nursing Faculty Research and Publications
A nurse residency program’s best practice recommendations are presented within this article and are organized around three processes: establishing the program infrastructure, creating a multistaged evidence-based program, and sustaining the program through appropriate evaluation and dissemination of results. These recommendations represent lessons learned and key findings derived from a team of academic and nursing professional development educators after 7 years of residency program implementation at multiple rural and urban hospital sites. Organizations, regardless of size and resources, can use these recommendations to increase the likelihood of building a successful residency program.
Nontraumatic Oral Health Classification For Alternative Use Of Syndromic Data, Sherry Burrer, Howard Burkom, Christopher Okunseri, Laurie Barker, Valerie Robison
Nontraumatic Oral Health Classification For Alternative Use Of Syndromic Data, Sherry Burrer, Howard Burkom, Christopher Okunseri, Laurie Barker, Valerie Robison
School of Dentistry Faculty Research and Publications
There is increasing demand for ways to use syndromic surveillance data for population health surveillance. The authors developed a nontraumatic oral health classification that could provide timely burden estimates of oral health-related visits to North Carolina (NC) emergency departments (EDs) using BioSense syndromic data. A combination of literature review, input by subject matter experts, and analysis of syndromic data was employed to create a classification that used select chief complaint text and ICD-9-CM codes for visit inclusion and exclusion criteria. Visit estimates created using this classification could contribute to policy decisions aimed at reducing this unnecessary burden on NC EDs.
An Investigation Of The Perceptions Of Community Residents And Volunteer Researchers For The Community Health Of The Clarke Square Neighborhood, Meghan Jones, Kelly Dione
An Investigation Of The Perceptions Of Community Residents And Volunteer Researchers For The Community Health Of The Clarke Square Neighborhood, Meghan Jones, Kelly Dione
Professional Projects
The study explored the similarities and differences in community residents’ perceptions and volunteer researchers’ perceptions of community health indicators in the Clarke Square Neighborhood. The study sought to identify noteworthy differences between community residents’ perceptions and volunteer researchers’ perceptions, indicating the importance of including community members in community health research. In the study, community residents in the Clarke Square Neighborhood conducted a survey that had previously been done by volunteer researchers from the Urban Ecology Center and the Medical College of Wisconsin regarding community health indicators in the Clarke Square Neighborhood. The study also included a focus group, which discussed …
Topical Menthol, Ice, Peripheral Blood Flow, And Perceived Discomfort, Robert V. Topp, Elizabeth R. Ledford, Dean E. Jacks
Topical Menthol, Ice, Peripheral Blood Flow, And Perceived Discomfort, Robert V. Topp, Elizabeth R. Ledford, Dean E. Jacks
College of Nursing Faculty Research and Publications
Context : Injury management commonly includes decreasing arterial blood flow to the affected site in an attempt to reduce microvascular blood flow and edema and limit the induction of inflammation. Applied separately, ice and menthol gel decrease arterial blood flow, but the combined effects of ice and menthol gel on arterial blood flow are unknown.
Objectives : To compare radial artery blood flow, arterial diameter, and perceived discomfort before and after the application of 1 of 4 treatment conditions.
Design : Experimental crossover design.
Setting : Clinical laboratory.
Participants or Other Participants : Ten healthy men, 9 healthy women (mean …
A Retrospective Review Of Sliding Scale Vs. Basal/Bolus Insulin Protocols, Heidi L. Rymaszewski, Susan Breakwell
A Retrospective Review Of Sliding Scale Vs. Basal/Bolus Insulin Protocols, Heidi L. Rymaszewski, Susan Breakwell
College of Nursing Faculty Research and Publications
Purpose
The purpose was to assess the differences between subcutaneous basal/bolus and sliding scale insulin protocols in patients admitted with type 2 diabetes on non-critical care units.
Methods
A retrospective review of electronic medical records was conducted on a convenience sample of inpatients in a central-city teaching hospital.
Results
The findings were that basal/bolus protocols achieved American Diabetes Association glycemic targets on fasting, mean, and discharge blood glucoses.
Conclusions
This study provided insight into glycemic control and interdisciplinary education needs at this hospital. Evidence revealed that basal/bolus insulin protocols can achieve glycemic targets.
Lack Of Father Involvement In Research On Children With Autism Spectrum Disorder: Maternal Parenting Stress And Family Functioning, Norah L. Johnson, Pippa Simpson
Lack Of Father Involvement In Research On Children With Autism Spectrum Disorder: Maternal Parenting Stress And Family Functioning, Norah L. Johnson, Pippa Simpson
College of Nursing Faculty Research and Publications
Autism Spectrum Disorder (ASD) has an estimated prevalence of greater than 1% of people in the US. Caring for children with ASD is stressful and challenging for parents. The purpose of the study is to understand the ramifications of the findings of a spouse/father's lack of participation for a study focused on stress and family functioning that attempted to recruit both parents of a child with ASD. The Kruskal-Wallis test compared medians of three groups of mothers of children with ASD in order to assess differences in parenting stress and family functioning discrepancy depending on their marital status and spouse …
Conceptualizing Group Dynamics From Our Clients’ Perspective: Development Of The Conceptualization Of Group Dynamics Inventory, Kevin A. Tate Phd, Edil Torres Rivera, William L. Conwill, David Miller, Ana Puig
Conceptualizing Group Dynamics From Our Clients’ Perspective: Development Of The Conceptualization Of Group Dynamics Inventory, Kevin A. Tate Phd, Edil Torres Rivera, William L. Conwill, David Miller, Ana Puig
College of Nursing Faculty Research and Publications
There is a clear call in group counseling practice and training for evidence-based practice (ACA, 2005; ASGW, 2008; CACREP, 2009). At the same time, group counselors also are asked to keep clients' experience at the center of their work (ASGW, 2012). This article outlines the authors' effort to develop and study an instrument designed to measure group counselors' conceptualization skill using group members' subjective perceptions as a foundation. Descriptions of the instrument's internal reliability, construct validity, and generalizability will be presented, as well as suggestions for conducting research on this instrument in future studies.
The Effect Of Either Topical Menthol Or A Placebo On Functioning And Knee Pain Among Patients With Knee Oa, Robert V. Topp, Joseph A. Brosky, David Pieschel
The Effect Of Either Topical Menthol Or A Placebo On Functioning And Knee Pain Among Patients With Knee Oa, Robert V. Topp, Joseph A. Brosky, David Pieschel
College of Nursing Faculty Research and Publications
Osteoarthritis (OA) is a common health problem with symptoms including reduced functioning and joint pain. Protracted pharmacological management of knee OA is associated with side effects including gastrointestinal, renal, and neurological dysfunction.Menthol gels have been used with limited empirical support to relieve pain and improve functioning among individual with OA. The purpose of this study was to compare the ability to complete functional tasks and knee pain while completing functional tasks among patients with knee OA after topical application of either 3.5% menthol gel or an inert placebo gel. Twenty individuals with knee OA volunteered to complete 2 data collection …
Methodology Issues In Implementation Science, Robin Newhouse, Kathleen Bobay, Patricia C. Dykes, Kathleen R. Stevens, Marita Titler
Methodology Issues In Implementation Science, Robin Newhouse, Kathleen Bobay, Patricia C. Dykes, Kathleen R. Stevens, Marita Titler
College of Nursing Faculty Research and Publications
Background: Putting evidence into practice at the point of care delivery requires an understanding of implementation strategies that work, in what context and how.
Objective: To identify methodological issues in implementation science using 4 studies as cases and make recommendations for further methods development.
Research Design: Four cases are presented and methodological issues identified. For each issue raised, evidence on the state of the science is described.
Results: Issues in implementation science identified include diverse conceptual frameworks, potential weaknesses in pragmatic study designs, and the paucity of standard concepts and measurement.
Conclusions: Recommendations to advance methods in implementation include developing …
Measuring Nurses’ Impact On Health Care Quality: Progress, Challenges, And Future Directions, Susan L. Beck, Marianne E. Weiss, Nancy Ryan-Wenger, Nancy E. Donaldson, Carolyn Aydin, Gail L. Towsley, William Gardner
Measuring Nurses’ Impact On Health Care Quality: Progress, Challenges, And Future Directions, Susan L. Beck, Marianne E. Weiss, Nancy Ryan-Wenger, Nancy E. Donaldson, Carolyn Aydin, Gail L. Towsley, William Gardner
College of Nursing Faculty Research and Publications
Background: Quality measurement is central in efforts to improve health care delivery and financing. The Interdisciplinary Nursing Quality Research Initiative supported interdisciplinary research teams to address gaps in measuring the contributions of nursing to quality care.
Objective: To summarize the research of 4 interdisciplinary teams funded by The Interdisciplinary Nursing Quality Research Initiative and reflect on challenges and future directions to improving quality measurement.
Methods: Each team summarized their work including the targeted gap in measurement, the methods used, key results, and next steps. The authors discussed key challenges and recommended future directions.
Results: These exemplar projects addressed cross-cutting issues …
Psychometrics Of The Depressive Cognition Scale In Caregivers Of Persons With Autism Spectrum Disorders, Abir K. Bekhet, Jaclene A. Zauszniewski
Psychometrics Of The Depressive Cognition Scale In Caregivers Of Persons With Autism Spectrum Disorders, Abir K. Bekhet, Jaclene A. Zauszniewski
College of Nursing Faculty Research and Publications
Caregivers of persons with autism spectrum disorders (ASD) are prone to depression, and early identification of cognitive depressive symptoms is important to prevent the development of clinical depression. The Depressive Cognition Scale (DCS) can be used for early detection, but the scale's psychometrics has not been tested in caregivers of persons with ASD. In this study, 95 caregivers of persons with ASD completed the eight-item DCS and measures of caregiver burden and resourcefulness. A Cronbach's alpha of .90 indicated internal consistency. Construct validity was supported by significant correlations with caregiver burden (.59) and resourcefulness (− .57). Principal component factor analysis …
Correlations Between Internal And External Power Outputs During Weightlifting Exercise, Kristof Kipp, Chad Harris, Michelle B. Sabick
Correlations Between Internal And External Power Outputs During Weightlifting Exercise, Kristof Kipp, Chad Harris, Michelle B. Sabick
Exercise Science Faculty Research and Publications
Identifying loads that maximize mechanical power is important because training at such loads may optimize gains in dynamic athletic performance. The purpose of this study was to examine correlations between measures of external mechanical power output and internal mechanical joint power output across different loads during a weightlifting exercise. Ten subjects performed 3 sets of the clean exercise at 65, 75, and 85% of 1 repetition maximum (1RM). Peak external mechanical power output was calculated with 4 commonly used methods, whereas an inverse dynamics approach was used to calculate peak internal mechanical power output for the hip, knee, and ankle …
Reduction In Phencyclidine Induced Sensorimotor Gating Deficits In The Rat Following Increased System Xc − Activity In The Medial Prefrontal Cortex, Victoria Lutgen, Krista Qualmann, Jon M. Resch, Linghai Kong, Sujean Choi, David A. Baker
Reduction In Phencyclidine Induced Sensorimotor Gating Deficits In The Rat Following Increased System Xc − Activity In The Medial Prefrontal Cortex, Victoria Lutgen, Krista Qualmann, Jon M. Resch, Linghai Kong, Sujean Choi, David A. Baker
Biomedical Sciences Faculty Research and Publications
Rationale: Aspects of schizophrenia, including deficits in sensorimotor gating, have been linked to glutamate dysfunction and/or oxidative stress in the prefrontal cortex. System xc −, a cystine–glutamate antiporter, is a poorly understood mechanism that contributes to both cellular antioxidant capacity and glutamate homeostasis.
Objectives: Our goal was to determine whether increased system xc − activity within the prefrontal cortex would normalize a rodent measure of sensorimotor gating.
Methods: In situ hybridization was used to map messenger RNA (mRNA) expression of xCT, the active subunit of system xc −, in the prefrontal cortex. Prepulse inhibition was …
Changes In Orthodontic Treatment Modalities In The Past 20 Years: Exploring The Link Between Technology And Scientific Evidence, T. Gerard Bradley
Changes In Orthodontic Treatment Modalities In The Past 20 Years: Exploring The Link Between Technology And Scientific Evidence, T. Gerard Bradley
School of Dentistry Faculty Research and Publications
Statement of the issue: Is there a link between the many perceived advances in orthodontic techniques/therapy and science in the past 20 years? The purpose of this paper is to take five topics and match the perceptions with the scientific evidence. The variety of appliances and the swings in treatment philosophy have been dramatic, including the swing from extraction to non-extraction therapy, the introduction of space-age wires, appliances that grow mandibles, the introduction and extraordinary growth of Invisalign, and reduced friction brackets to reduce treatment time, all with claims by manufacturers of better results than ever before. The focus is …
Dimensional Changes Of Upper Airway After Rapid Maxillary Expansion: A Prospective Cone-Beam Computed Tomography Study, Yoon Hwan Chang, Lisa J. Koenig, Jessica E. Pruszynski, T. Gerard Bradley, Jose A. Bosio, Dawei Liu
Dimensional Changes Of Upper Airway After Rapid Maxillary Expansion: A Prospective Cone-Beam Computed Tomography Study, Yoon Hwan Chang, Lisa J. Koenig, Jessica E. Pruszynski, T. Gerard Bradley, Jose A. Bosio, Dawei Liu
School of Dentistry Faculty Research and Publications
Introduction: The aim of this prospective study was to use cone-beam computed tomography to assess the dimensional changes of the upper airway in orthodontic patients with maxillary constriction treated by rapid maxillary expansion.
Methods: Fourteen orthodontic patients (mean age, 12.9 years; range, 9.7-16 years) were recruited. The patients with posterior crossbite and constricted maxilla were treated with rapid maxillary expansion as the initial part of their comprehensive orthodontic treatments. Before and after rapid maxillary expansion conebeam computed tomography scans were taken to measure the retropalatal and retroglossal airway changes in terms of volume, and sagittal and cross-sectional areas. The transverse …