Medicine and Health Sciences Commons^™

The Effects Of Dentin Adhesives And Liner Materials On The Microleakage Of Class Ii Resin Composite Restorations In Primary And Permanent Teeth, H. Cem Güngör, E. Canoğlu, Z. C. Çehreli

School of Dentistry Faculty Research and Publications

Purpose

To compare the occlusal and gingival microleakage of Class-II composite restorations utilizing etch-and-rinse and self-etch adhesives and different liner materials in primary and permanent teeth.

Study design

Standardized class-II cavities were prepared in freshly-extracted sound primary and permanent molars (n = 80/each), with all cavosurface margins involving enamel. The main experimental groups were; A. Single Bond 2/primary teeth; B. Adper SE Plus/primary teeth; C. Single Bond 2/permanent teeth; and D. Adper SE Plus/permanent teeth. Each group comprised 4 subgroups (n = 10/each) with respect to the liner material employed (n = 10/subgroup): 1. Fuji VII; 2. Fuji Triage; 3. …

Management Of Crown-Related Fractures In Children: An Update Review, H. Cem Güngör

School of Dentistry Faculty Research and Publications

Traumatic dental injuries (TDIs) are a serious public health problem. Epidemiology of dental trauma indicates that these injuries are more prevalent in child population of the world. Children are the sufferers in two-thirds of all TDIs observed. Although being a major fraction, crown-related fractures are a less severe form of TDIs with respect to their complications and sequelae. However, as with other types of traumatic injuries, the delay in seeking for immediate care following a traumatic injury and the lack of appropriate treatment may compromise long-term outcomes. This article reviews the occurrence, management, and prognosis of crown-related fractures in primary …

Detection Of Parasite-Specific Dna In Urine Sediment Obtained By Filtration Differentiates Between Single And Mixed Infections Of Schistosoma Mansoni And S. Haematobium From Endemic Areas In Ghana, Nilanjan Lodh, Jean M. Naples, Kwabena M. Bosompem, Joseph Quartey, Clive J. Shiff

Clinical Lab Sciences Faculty Research and Publications

Differential diagnosis of Schistosoma mansoni and S. haematobium, which often occur sympatrically in Africa, requires both urine and stool and the procedures are low in sensitivity. The standard diagnostic tests, such as Kato-Katz (KK) for S. mansoni eggs and presence of haematuria for S. haematobium both lack sensitivity, produce false-negative results and show reduced accuracy with decreasing intensity of infection. The need for a single diagnostic test with high sensitivity and specificity for both parasites is important as many African countries are implementing Mass Drug Administration (MDA) following recommendations of the World Health Organization (WHO). Eighty-six samples of urine …

Nature Of The Neurotoxic Membrane Actions Of Amyloid-Β On Hippocampal Neurons In Alzheimer's Disease, Fernando J. Sepúlveda, Humberto Fierro, Eduardo Fernandez, Carolina Castillo, Robert W. Peoples, Carlos Opazo, Luis G. Aguayo

Biomedical Sciences Faculty Research and Publications

The mechanism by which amyloid-β (Aβ) produces brain dysfunction in patients with Alzheimer's disease is largely unknown. According to previous studies, Aβ might share perforating properties with gramicidin, a well-accepted membrane-disrupting peptide. Therefore, we hypothesize that the key steps leading to synaptotoxicity by Aβ and gramicidin involve peptide aggregation, pore formation, and calcium dysregulation. Here, we show that Aβ and gramicidin form aggregates enriched in β-sheet structures using electron microscopy, and Thioflavin and Congo Red staining techniques. Also, we found that Aβ and gramicidin display fairly similar actions in hippocampal cell membranes, i.e. inducing Ca²⁺ entry and synaptoxicity characterized …

Compassion Fatigue: An Unwanted Reflection Of Your Reality, Kathryn Schroeter

College of Nursing Faculty Research and Publications

No abstract provided.

Teaching Culturally Sensitive Care To Dental Students: A Multidisciplinary Approach, Evelyn Donate-Bartfield, William K. Lobb, Toni M. Roucka

School of Dentistry Faculty Research and Publications

Dental schools must prepare future dentists to deliver culturally sensitive care to diverse patient populations, but there is little agreement on how best to teach these skills to students. This article examines this question by exploring the historical and theoretical foundations of this area of education in dentistry, analyzes what is needed for students to learn to provide culturally sensitive care in a dental setting, and identifies the discipline-specific skills students must master to develop this competence. The problems associated with single-discipline, lecture-based approaches to teaching culturally sensitive care are outlined, and the advantages of an interdisciplinary, patient-centered, skills-based approach …

Effect Of Fontan Fenestration On Regional Venous Oxygen Saturation During Exercise: Further Insights Into Fontan Fenestration Closure, Rohit S. Loomba, Michael E. Danduran, Jennifer E. Dixon, Rohit P. Rao

Exercise Science Faculty Research and Publications

Fontan fenestration closure is a topic of great debate. The body of data regarding the risks and benefits of fenestration closure is limited yet growing. Previous studies have demonstrated that Fontan patients have less exercise capacity than those with normal cardiovascular anatomy. Differences also have been noted within various subgroups of Fontan patients such as whether Fontan is fenestrated or not. This study aimed to compare trends in regional oxygen saturations using near-infrared spectroscopy (NIRS) in patients with Fontan circulations during ramping exercise to further delineate differences between patients with and without a fenestration. It was hypothesized that Fontan patients …

Fostering Dental Faculty Collaboration With An Evidence-Based Decision Making Model Designed For Curricular Change, Gary L. Stafford

School of Dentistry Faculty Research and Publications

This article introduces an innovative decision making model for adapting evidence-based practice to the specific needs of a department in a dental school. The design encourages suggestions for curricular change directly from the faculty members, while providing a mechanism that allows them to actively participate in the process through the use of evidence-based principles and practice. The nucleus of this model is an Advisory Council comprised of nine full-time departmental faculty members who, when charged, act as independent task force leaders who recruit other faculty members and lead small teams that investigate suggestions for curricular change. Following an accelerated investigative …

Current Medical Research Winter–Spring 2013, Richard J. Fehring

College of Nursing Faculty Research and Publications

No abstract provided.

Individual Characteristics And Relocation Factors Affecting Adjustment Among Relocated American And Egyptian Older Adults, Abir K. Bekhet, Jaclene A. Zauszniewski

College of Nursing Faculty Research and Publications

Worldwide, the population of elders is increasing significantly. Relocation can be a positive or a negative experience, depending on many factors, including culture. The purpose of this study is to compare individual characteristics (age, gender, marital status, education, perceived health status, activities of daily living), relocation factors (movement preparation, time passed since relocation, closeness of prior home to the present, and whether relocation was from home or another facility), and adjustment in relocated American and Egyptian elders. This secondary analysis study merged data from two cross-sectional descriptive studies of a 104 elders relocated to retirement communities in Northeast Ohio and …

Electrical Stimulation Technologies For Wound Healing, Luther C. Kloth

Physical Therapy Faculty Research and Publications

Objective: To discuss the physiological bases for using exogenously applied electric field (EF) energy to enhance wound healing with conductive electrical stimulation (ES) devices.

Approach: To describe the types of electrical currents that have been reported to enhance chronic wound-healing rate and closure.

Results: Commercial ES devices that generate direct current (DC), and mono and biphasic pulsed current waveforms represent the principal ES technologies which are reported to enhance wound healing.

Innovation: Wafer-thin, disposable ES technologies (wound dressings) that utilize mini or micro-batteries to deliver low-level DC for wound healing and antibacterial wound-treatment purposes are commercially available. Microfluidic wound-healing chips …

Fgf-2 Induces Neuronal Death Through Upregulation Of System Xc-, Xiaoqian Liu, Rebecca Albano, Doug Lobner

Biomedical Sciences Faculty Research and Publications

The cystine/glutamate antiporter (system xc-) transports cystine into cell in exchange for glutamate. Fibroblast growth factor-2 (FGF-2) upregulates system xc- selectively on astrocytes, which leads to increased cystine uptake, the substrate for glutathione production, and increased glutamate release. While increased intracellular glutathione can limit oxidative stress, the increased glutamate release can potentially lead to excitotoxicity to neurons. To test this hypothesis, mixed neuronal and glial cortical cultures were treated with FGF-2. Treatment with FGF-2 for 48 h caused a significant neuronal death in these cultures. Cell death was not observed in neuronal-enriched cultures, or astrocyte-enriched …

Validation Of Patient And Nurse Short Forms Of The Readiness For Hospital Discharge Scale And Their Relationship To Return To The Hospital, Marianne E. Weiss, Linda L. Costa, Kathleen Bobay, Olga Yakusheva

College of Nursing Faculty Research and Publications

Objective: To validate patient and nurse short forms for discharge readiness assessment and their associations with 30-day readmissions and emergency department (ED) visits.

Data Sources/Study Setting: A total of 254 adult medical-surgical patients and their discharging nurses from an Eastern US tertiary hospital between May and November, 2011. Study Design Prospective longitudinal design, multinomial logistic regression analysis.

Data Collection/Extraction Methods: Nurses and patients independently completed an eight-item Readiness for Hospital Discharge Scale on the day of discharge. Patient characteristics, readmissions, and ED visits were electronically abstracted.

Principal Findings: Nurse assessment of low discharge readiness was associated with a six- to …

A Feminist Perspective On Listening To Women: Birth Stories Of Vaginal Birth Following Previous Cesarean Delivery, Elizabeth Hill-Karbowski

Dissertations (1934 -)

Women's perspectives of their experiences are important, and worthy of study. However, there have been no qualitative comparative investigations of vaginal birth after cesarean (VBAC) experiences of American women using their birth stories as data. Furthermore, there have been no studies where women's experiences of cesarean have been compared with their own subsequent VBAC.

The purpose of this study was to gain insight into the comparative experience of VBAC and cesarean, valuing women and their experiences through the use of a feminist research perspective. By contributing new and valuable insight into an area of research that has been identified as …

Articulatory Kinematics Of Alternating And Sequential Motion Rate Diadochokinesis, Jeffrey J. Berry, Scott Palahniuk, Emily Isaksson, Marki Romenesko

Speech Pathology and Audiology Faculty Research and Publications

No abstract provided.

Two-Method Planned Missing Designs For Longitudinal Research, Mauricio Garnier-Villarreal, Mijke Rhemtulla, Todd D. Little

College of Nursing Faculty Research and Publications

We examine longitudinal extensions of the two-method measurement design, which uses planned missingness to optimize cost-efficiency and validity of hard-to-measure constructs. These designs use a combination of two measures: a “gold standard” that is highly valid but expensive to administer, and an inexpensive (e.g., survey-based) measure that contains systematic measurement bias (e.g., response bias). Using simulated data on four measurement occasions, we compared the cost-efficiency and validity of longitudinal designs where the gold standard is measured at one or more measurement occasions. We manipulated the nature of the response bias over time (constant, increasing, fluctuating), the factorial structure of the …

Physical Therapy In Wound Healing, Edema, And Urinary Incontinence, Jakub Taradaj, Tomasz Urbanek, Luther C. Kloth, Marco Romanelli

Physical Therapy Faculty Research and Publications

No abstract provided.

Contributions Of The Pre-Bötzinger Complex And The Kölliker-Fuse Nuclei To Respiratory Rhythm And Pattern Generation In Awake And Sleeping Goats, Hubert Forster, Joshua M. Bonis, Katie L. Krause, Julie Wenninger, Suzanne Neumueller, Matthew Hodges, Lawrence Pan

Physical Therapy Faculty Research and Publications

We investigated in three groups of awake and sleeping goats whether there are differences in ventilatory responses after injections of Ibotenic acid (IA, glutamate receptor agonist and neurotoxin) into the pre-Bötzinger complex (preBötC), lateral parabrachial (LPBN), medial (MPBN) parabrachial, or Kölliker-Fuse nuclei (KFN). In one group, within minutes after bilateral injection of 10 μl IA (50 mM) into the preBötC, there was a 10-fold increase in breathing frequency, but 1.5 h later, the goats succumbed to terminal apnea. These data are consistent with findings in reduced preparations that the preBötC is critical to sustaining normal breathing. In a second group, …

The Role Of Aerobic Physical Fitness In Overweight Adolescents, Stacy Stolzman, Jenna Speltz, Katherine Hoffmeister, Michael E. Danduran, Joseph Skelton, Paula E. Papanek, April L. Harkins, Marie K. Hoeger Bement

Physical Therapy Faculty Research and Publications

No abstract provided.

Influence Of Social Class Perceptions On Attributions Among Mental Health Practitioners, Mindi Thompson, Jacob Diestelmann, Odessa Cole, Abiola O. Keller, Takuya Minami

Physician Assistant Studies Faculty Research and Publications

Objective: A vignette-based study assessed the influence of social class attributions toward a hypothetical client's difficulty. Method: 188 licensed mental health professionals who were recruited through professional listservs completed an online survey after reviewing one of two versions of a vignette describing a hypothetical client that varied based on social class cues. Results: As expected, this sample of licensed mental health practitioners detected social class differences based on the descriptors of the hypothetical client across the two vignettes. These perceived social class differences, however, did not impact participants' attributions toward the client for causing or solving her problems, level of …

Neurobiological Mechanisms That Contribute To Stress-Related Cocaine Use, John R. Mantsch, Oliver Vranjkovic, Robert C. Twining, Paul J. Gasser, Jayme R. Mcreynolds, Jordan M. Blacktop

Biomedical Sciences Faculty Research and Publications

The ability of stressful life events to trigger drug use is particularly problematic for the management of cocaine addiction due to the unpredictable and often uncontrollable nature of stress. For this reason, understanding the neurobiological processes that contribute to stress-related drug use is important for the development of new and more effective treatment strategies aimed at minimizing the role of stress in the addiction cycle. In this review we discuss the neurocircuitry that has been implicated in stress-induced drug use with an emphasis on corticotropin releasing factor actions in the ventral tegmental area (VTA) and an important pathway from the …

Consonant Context Effects On Sensorimotor Adaptation Of Vowel Production, Jeffrey J. Berry, John Jaeger Iv, Brittany A. Bernal, Rachael Hefel, Julia Wesley

Speech Pathology and Audiology Faculty Research and Publications

No abstract provided.

Dynamic Aspects Of Articulating With A Virtual Vocal Tract In Dysarthria, Jeffrey J. Berry, Cassandra North, Michael T. Johnson

Speech Pathology and Audiology Faculty Research and Publications

No abstract provided.

The Impact Of Patient–Provider Communication And Language Spoken On Adequacy Of Depression Treatment For U.S. Women, Abiola O. Keller, Ronald Gangnon, Whitney P. Witt

College of Nursing Faculty Research and Publications

Many women with depression are untreated or undertreated for their condition. The quality of patient–provider communication may impact the receipt of depression treatment. We examine the relationship between patient–provider communication and receipt of adequate treatment for depression among women. The study sample consisted of women with depression who visited a provider in the previous 12 months in the 2002–2008 Medical Expenditure Panel Survey (N = 3,179). Multivariate regression was used to examine the independent contribution of sociodemographic characteristics, health care factors, patient–provider communication, and respondent language on depression treatment status (none, some, adequate). We found that more than one-third of …

Prueba Go/No-Go, Mauricio Garnier-Villarreal, Luis Diego Conejo Bolaños

College of Nursing Faculty Research and Publications

No abstract provided.

Family Caregivers’ Knowledge Of Delirium And Preferred Modalities For Receipt Of Information, Margaret J. Bull, Lesley Boaz, Jennifer M. Sjostedt

College of Nursing Faculty Research and Publications

Delirium is a life-threatening, frequently reversible condition that is often a sign of an underlying health problem. In-hospital mortality alone for older adults with delirium ranges from 25% to 33%. Early recognition of delirium is critical because prolonged duration poses a greater risk of poor functional outcomes for older adults. Family caregivers, who are familiar with the older adult’s usual behaviors, are most likely to recognize delirium symptoms but might dismiss them as due to aging. It is important to learn what family caregivers know about delirium to ascertain their need for education. The aims of this study were to …

Strategies For A Successful Phd Program: Words Of Wisdom From The Wjnr Editorial Board, Vicki S. Conn, Julie Zerwic, Susan M. Rawl, Jean F. Wyman, Janet L. Larson, Cindy M. Anderson, Nancy L. Fahrenwald, Lazelle E. Benefield, Marlene Z. Cohen, Carol E. Smith, Robert V. Topp, Natalie E. Markis

College of Nursing Faculty Research and Publications

Nursing doctoral programs prepare students for research-focused careers within academic settings. The purpose of this Editorial Board Special Article is to provide PhD students and advisors with suggestions for making the most of their doctoral experience. Editorial Board members provide their individual insights on the skills and attributes students must acquire during the course of their doctoral education in order to succeed. The authors provide practical tips and advice on how to excel in a PhD program, including how to select an advisor and a dissertation committee, the importance of attending conferences to increase visibility and develop a network of …

A Comparison Of Quality Of Care In Critical Access Hospitals And Other Rural Hospitals, Marianne Baernholdt, Jessica Keim-Malpass, Ivora D. Hinton, Guofen Yan, Marilyn Meyer Bratt

College of Nursing Faculty Research and Publications

Purpose:

The United States has about 2100 rural hospitals. Approximately 1300 are Critical Access Hospitals (CAHs) with 25 beds or less. CAHs receive cost-based reimbursement through the federal Flex program with the goal to improve quality and access to health care. Reports on quality of care (QOC) and factors that influence quality in CAHs are mixed. This study compared QOC and factors that influence QOC in CAHs and other rural hospitals.

Sample: 385 staff nurses in 6 CAHs and 9 other rural hospitals in North Carolina and Virginia.

Method:

Descriptive cross-sectional design using nurse surveys aggregated to the hospital level, …

Psychometric Evaluation Of An Instrument To Measure Hispanic Mothers’ Normative Beliefs, Intentions, Past Experience And Past Behavior Related To The Discussion Of Sex-Related Topics With Their Adolescent Daughters, Dana Rodriguez, Robert V. Topp, Richard J. Fehring

College of Nursing Faculty Research and Publications

Aim: The aim of this project was to describe the psychometric properties of a recently developed instrument that measures Hispanic mother normative beliefs, intentions, past experience, and past behavior regarding the Discussion of Sex-Related Topics (DSRTs) with their adolescent daughters.

Background: The DSRTs between Hispanic mothers and their adolescent daughters is important because this interaction has been found to be a protective factor against the daughter’s risk for STDs and unintended pregnancy. Hispanic mother talk less with their daughters about sex-related topics (SRTs) than other ethnic groups. The Rodriguez Normative Belief Instrument (RNBI) has been established to measure …

Exploring Essential Characteristics Of Self-Determination For Diverse Students Using Data From Nlts2, Karrie A. Shogren, William Kennedy, Chantelle Dowsett, Mauricio Garnier-Villarreal, Todd D. Little

College of Nursing Faculty Research and Publications

This study explored the impact of race/ethnicity on three of the four essential characteristics of self-determination—autonomy, self-realization, and psychological empowerment—directly assessed in the National Longitudinal Transition Study-2. Specifically, the impact of race/ethnicity was examined with six disability groups established in previous research: high incidence disabilities (learning disabilities, emotional disturbances, speech language impairments, and other health impairments), sensory disabilities (visual and hearing impairments), cognitive disabilities (autism, multiple disabilities, and deaf-blindness); intellectual disability, traumatic brain injury, and orthopedic impairments. Measurement equivalence was established across groups, but significant differences in the latent means, variances, and covariances were found suggesting a complex pattern of …