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Articles 601 - 630 of 4977
Full-Text Articles in Medicine and Health Sciences
Understanding Perceptions, Attitudes And Experiences Of Nursing Students During Clinical Placement In Primary Health Care Settings – A Scoping Review, Debbie Procter, Kylie Mccullough, Debbie Massey, Karen Strickland
Understanding Perceptions, Attitudes And Experiences Of Nursing Students During Clinical Placement In Primary Health Care Settings – A Scoping Review, Debbie Procter, Kylie Mccullough, Debbie Massey, Karen Strickland
Research outputs 2022 to 2026
Aims: Critically analyse literature on undergraduate nursing students' perceptions, attitudes and experiences during Primary Health Care (PHC) placements and identify factors influencing their satisfaction. These insights may improve educational outcomes, shape career intentions and address workforce shortages. Background: Global nursing shortage, driven by increased demands and high attrition, impacts healthcare worldwide. Australia faces projected shortfalls of 79,473 nurses by 2035, significantly in PHC. Attributing factors include remuneration disparities, inadequate training/mentorship and limited career pathways. Strengthening the PHC nursing workforce is crucial, with undergraduate nursing students providing an important workforce pipeline. Design/Method: Scoping Review protocol was registered using Joanna Briggs Institute's …
A Cross-Sectional Examination Of Missed Infection Control Practices Among Nurses In The Jordanian Hospitals, Muhammad Ahmed Alshyyab, Rania Ali Albsoul, Gerard Fitzgerald, Diana Arabiat
A Cross-Sectional Examination Of Missed Infection Control Practices Among Nurses In The Jordanian Hospitals, Muhammad Ahmed Alshyyab, Rania Ali Albsoul, Gerard Fitzgerald, Diana Arabiat
Research outputs 2022 to 2026
Background: Missed infection control practices may negatively impact quality healthcare and patient safety in acute health care settings. Hence, more research is urgently needed especially in Arab countries. To investigate the elements and reasons of missed infection control activities among nurses in Jordan. The sociodemographic correlates with missed infection control activities were also examined. Methods: A cross sectional design was utilized in this study. A convenience sample of 960 nurses from seven hospitals in the North of Jordan was used. The Missed Nursing Care Infection Prevention and Control (MNCIPC) Survey was employed to collect the data. Data were analyzed using …
Rural Cancer Survivors' Perceived Delays In Seeking Medical Attention, Diagnosis And Treatment: Findings From A Large Qualitative Study, Alyssa Taglieri-Sclocchi, Ingrid Bindicsova, Susannah K. Ayre, Michael Ireland, Sonja March, Fiona Crawford-Williams, Suzanne Chambers, Jeff Dunn, Belinda C. Goodwin, Elizabeth A. Johnston
Rural Cancer Survivors' Perceived Delays In Seeking Medical Attention, Diagnosis And Treatment: Findings From A Large Qualitative Study, Alyssa Taglieri-Sclocchi, Ingrid Bindicsova, Susannah K. Ayre, Michael Ireland, Sonja March, Fiona Crawford-Williams, Suzanne Chambers, Jeff Dunn, Belinda C. Goodwin, Elizabeth A. Johnston
Research outputs 2022 to 2026
Aims: To investigate rural cancer survivors' self-reported reasons for perceived delays in initial cancer detection and treatment. Methods: Within a cohort study, adult cancer survivors who had travelled > 50 km for cancer care, staying at subsidised accommodation lodges in city centres in Queensland, Australia, were invited to complete a structured interview on perceived delays in: (i) seeking medical attention, (ii) receiving their diagnosis and (iii) commencing treatment. Content analysis was used to map self-reported reasons for perceived delays at each step, which were then categorised based on the perceived source: (i) personal, (ii) healthcare professional, (iii) healthcare system or (iv) …
The Therapeutic Potential Of Butyrate And Lauric Acid In Modulating Glial And Neuronal Activity In Alzheimer’S Disease, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Lotta E. Oikari, Prashant Bharadwaj, Vijay Jayasena, Ralph N. Martins, Wanakulasuriya Mary Ann Dipika Binosha Fernando
The Therapeutic Potential Of Butyrate And Lauric Acid In Modulating Glial And Neuronal Activity In Alzheimer’S Disease, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Lotta E. Oikari, Prashant Bharadwaj, Vijay Jayasena, Ralph N. Martins, Wanakulasuriya Mary Ann Dipika Binosha Fernando
Research outputs 2022 to 2026
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by amyloid-β plaque accumulation, tau tangles, and extensive neuroinflammation. Neuroinflammation, driven by glial cells like microglia and astrocytes, plays a critical role in AD progression. Initially, these cells provide protective functions, such as debris clearance and neurotrophic support. However, as AD progresses, chronic activation of these cells exacerbates inflammation, contributing to synaptic dysfunction, neuronal loss, and cognitive decline. Microglia release pro-inflammatory cytokines and reactive oxygen species (ROS), while astrocytes undergo reactive astrogliosis, further impairing neuronal health. This maladaptive response from glial cells significantly accelerates disease pathology. Current AD treatments primarily aim …
What Are Safe Hemoglobin, Neutrophil And Platelet Counts For People With Hematological Malignancies To Participate In Exercise And Activities Of Daily Living: A Scoping Review, Joanne L. Houston, Kieran P. Boyd, Paul M. Gittings, Vinicius Cavalheri
What Are Safe Hemoglobin, Neutrophil And Platelet Counts For People With Hematological Malignancies To Participate In Exercise And Activities Of Daily Living: A Scoping Review, Joanne L. Houston, Kieran P. Boyd, Paul M. Gittings, Vinicius Cavalheri
Research outputs 2022 to 2026
Purpose: The aim of this scoping review was to summarize the extent of the literature in relation to safe levels of platelet, hemoglobin and neutrophil count for people with hematological cancers to participate in exercise or activities of daily living (ADLs). Methods: A comprehensive search for this scoping review was completed in July 2024 across five databases: the Cochrane Library, Embase, PEDro, PubMed and OTSeeker. Original studies, reviews and expert opinion papers were included if they focused on people with active hematological cancer diagnoses or those undergoing treatment affecting bone marrow, and referenced safe levels of platelet, hemoglobin and neutrophil …
Exercise Effects On Symptoms Of Depression And Anxiety Vary By Patient, Clinical, And Intervention Characteristics In Cancer Survivors: Results From Pooled Analyses Of Individual Participant Data Of 26 Rcts, Marlou Floor Kenkhuis, Meike Doorenbos, Isa H. Mast, Neil K. Aaronson, Marc Van Beurden, Martin Bohus, Kerry S. Courneya, Amanda J. Daley, Daniel A. Galvão, Martine M. Goedendorp, Wim H. Van Harten, Sandi C. Hayes, Anouk E. Hiensch, Melinda L. Irwin, Marie José Kersten, Hans Knoop, Anne M. May, Alex Mcconnachie, Willem Van Mechelen, Nanette Mutrie, Robert U. Newton, Frans Nollet, Hester S. Oldenburg, Martina E. Schmidt, Kathryn H. Schmitz, Karl Heinz Schulz, Dennis R. Taaffe
Exercise Effects On Symptoms Of Depression And Anxiety Vary By Patient, Clinical, And Intervention Characteristics In Cancer Survivors: Results From Pooled Analyses Of Individual Participant Data Of 26 Rcts, Marlou Floor Kenkhuis, Meike Doorenbos, Isa H. Mast, Neil K. Aaronson, Marc Van Beurden, Martin Bohus, Kerry S. Courneya, Amanda J. Daley, Daniel A. Galvão, Martine M. Goedendorp, Wim H. Van Harten, Sandi C. Hayes, Anouk E. Hiensch, Melinda L. Irwin, Marie José Kersten, Hans Knoop, Anne M. May, Alex Mcconnachie, Willem Van Mechelen, Nanette Mutrie, Robert U. Newton, Frans Nollet, Hester S. Oldenburg, Martina E. Schmidt, Kathryn H. Schmitz, Karl Heinz Schulz, Dennis R. Taaffe
Research outputs 2022 to 2026
Purpose: This study aimed to investigate whether socio-demographic, clinical, and intervention-related variables moderate the effects of exercise on depression and anxiety symptoms in cancer survivors. Methods: Data from 26 RCTs in the POLARIS database were analyzed using a one-step individual participant data (IPD) meta-analytic approach with linear mixed models to assess exercise effects on depression and anxiety symptoms (z-scores). Interaction terms were added to these models to explore moderators. Results are presented as betas (corresponding to Cohen’s d effect size). Results: Albeit statistically significant, exercise demonstrated negligible effects on symptoms of depression (β = − 0.11; 95% CI = − …
Foundations And Strategic Vision Of The Canadian Translational Geroscience Network, Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Gilles Gouspillou, Lea Harrington, James L. Kirkland, George A. Kuchel, Jeremy Van Raamsdonk, R. Jane Rylett, Chantal Autexier, Louis R. Lapierre, Michael Kobor, Mohammad Auais, Ann Beliën, Jeroen Aerssens, George Sutphin, Kenneth Rockwood, Alexandra Papaioannou, Marc Sim, Jamie Justice, Nancy Mayo, Gustavo Duque
Foundations And Strategic Vision Of The Canadian Translational Geroscience Network, Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Gilles Gouspillou, Lea Harrington, James L. Kirkland, George A. Kuchel, Jeremy Van Raamsdonk, R. Jane Rylett, Chantal Autexier, Louis R. Lapierre, Michael Kobor, Mohammad Auais, Ann Beliën, Jeroen Aerssens, George Sutphin, Kenneth Rockwood, Alexandra Papaioannou, Marc Sim, Jamie Justice, Nancy Mayo, Gustavo Duque
Research outputs 2022 to 2026
Geroscience is an emerging interdisciplinary field that explores the biological connections between aging and the development of chronic diseases, with the ultimate goal of identifying interventions to extend healthspan and delay age-related conditions. Recognizing the growing importance of this field, the Canadian Translational Geroscience Network (geroscience.ca) was officially launched during a conference held in Montreal on September 5-6, 2024. Building on the momentum of successful Geroscience meetings in Toronto and Montreal in 2023, this milestone event marked a transformative step forward for geroscience in Canada. This event brought together key stakeholders, including the Canadian Frailty Network (CFN), the Canadian Institutes …
Models Of Care For Indigenous Children In Rural And Remote Settings: A Global Scoping Review, Joseph Freeman, Thomas Stubbs, Verity Chadwick, Anita Pickard, Tuguy Esgin, Elizabeth J. Elliott, Alexandra Martiniuk
Models Of Care For Indigenous Children In Rural And Remote Settings: A Global Scoping Review, Joseph Freeman, Thomas Stubbs, Verity Chadwick, Anita Pickard, Tuguy Esgin, Elizabeth J. Elliott, Alexandra Martiniuk
Research outputs 2022 to 2026
Indigenous communities internationally have demonstrated remarkable strength despite significant challenges. Health disparities among Indigenous peoples persist due to historical injustices and ongoing racial discrimination, not inherent vulnerabilities. Disparities are rooted in a legacy of colonisation, systemic exclusion, and socio-economic inequities impacting access to healthcare, education, and employment. Preliminary searches show limited literature on models of care for remote living Indigenous children. This review aimed to identify internationally, effective models of care for Indigenous children in rural and remote areas. A scoping review was conducted, analysing literature on models of care for remote Indigenous children. This study followed the JBI’s Scoping …
Amyloid Accumulation, Brain Atrophy, And Cognitive Decline In Emergent Alzheimer's Disease, Ying Xia, Pierrick Bourgeat, Vincent Doré, Jurgen Fripp, Yen Ying Lim, Simon M. Laws, Christopher Fowler, Christopher C. Rowe, Colin L. Masters, Elizabeth J. Coulson, Paul Maruff
Amyloid Accumulation, Brain Atrophy, And Cognitive Decline In Emergent Alzheimer's Disease, Ying Xia, Pierrick Bourgeat, Vincent Doré, Jurgen Fripp, Yen Ying Lim, Simon M. Laws, Christopher Fowler, Christopher C. Rowe, Colin L. Masters, Elizabeth J. Coulson, Paul Maruff
Research outputs 2022 to 2026
Introduction : Emergent Alzheimer's disease (AD) represents a transitional stage where cognitively unimpaired (CU) individuals exhibit subthreshold but increasing amyloid-β (Aβ) levels. The impact of Aβ accumulation on brain volume loss and cognition during this early stage remains unclear. Methods: This retrospective cohort study analyzed data from 408 CU participants who were initially Aβ− (< 15 Centiloids) and followed for up to 15 years. Changes in basal forebrain and hippocampal volume, along with domain-specific cognitive performance, were compared between those who progressed to Aβ+ (≥20 Centiloids) and those who remained Aβ−. Results: Sixty-five CU participants progressed to Aβ+, indicating emergent AD, and showed faster Aβ accumulation and subtle memory decline. However, no significant differences in rate of BF and hippocampal atrophy were observed between groups. Discussion: The results suggest that during this emergent phase of AD, Aβ accumulation is associated with episodic memory loss, in the absence of detectable accelerated brain atrophy. Highlights: Identified cognitively unimpaired individuals in the emergent stage of Alzheimer's disease (AD). Emergent AD exhibits a greater rate of amyloid-β (Aβ) accumulation. No accelerated volume loss detected in the basal forebrain or hippocampus. Emergent AD is also associated with a subtle decline in memory. Early Aβ accumulation may impair cognitive function before structural atrophy.
Postoperative Care Pathways For Patients Following Coronary Artery Bypass Grafting Surgery: An Observational Study, Dima Nasrawi, Sharon Latimer, Debbie Massey, Brigid M. Gillespie
Postoperative Care Pathways For Patients Following Coronary Artery Bypass Grafting Surgery: An Observational Study, Dima Nasrawi, Sharon Latimer, Debbie Massey, Brigid M. Gillespie
Research outputs 2022 to 2026
Aims: The aim of this study was to describe the postoperative care pathway, with phase 1 cardiac rehabilitation (CR) delivery, for adult patients following coronary artery bypass grafting (CABG) surgery at one large hospital in Queensland, Australia. Design and methods: This observational study involved structured observations, patient electronic medical record audits, and field notes to gather postoperative data. Four continuous hours of patient and healthcare professional (HCP) observations gathered at 30-min intervals occurred on 12 separate days over a 1-month period (February–March 2023). We observed post-CABG patients and HCPs involved in delivering direct care. Data were gathered on the clinical …
Midwifery Students' Evaluation Of Midwifery Practice Experiences In Australia: A National Survey, F. Bogossian, A. Hyun, D. Bloxsome, A. Brown, S. Cooper, S. Hunter, L. Kearney
Midwifery Students' Evaluation Of Midwifery Practice Experiences In Australia: A National Survey, F. Bogossian, A. Hyun, D. Bloxsome, A. Brown, S. Cooper, S. Hunter, L. Kearney
Research outputs 2022 to 2026
Aim: To report the findings of the first 12 months of a national survey of midwifery students’ evaluation of midwifery practice experiences in Australia. Background: Accreditation standards for midwifery programs globally and in Australia, require evidence of monitoring and evaluation of student midwifery practice experiences. In 2022 the National Placement Evaluation Centre was commissioned to measure and enhance the quality of nursing and midwifery practice experiences. Design: Survey Methods: A national survey of midwifery students who completed midwifery practice experience in Australia between 1 July 2023 and 30 June 2024. Results: Midwifery practice experiences (n = 871) were evaluated; most …
Breast And Prostate Cancer Survivors’ Understanding Of Risk And Management Of Cardiovascular And Musculoskeletal Side Effects Of Treatment: Findings From Focus Groups, Jack Dalla Via, Chris R. Andrew, Brenton J. Baguley, Nina Stewart, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley, Mary A. Kennedy
Breast And Prostate Cancer Survivors’ Understanding Of Risk And Management Of Cardiovascular And Musculoskeletal Side Effects Of Treatment: Findings From Focus Groups, Jack Dalla Via, Chris R. Andrew, Brenton J. Baguley, Nina Stewart, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley, Mary A. Kennedy
Research outputs 2022 to 2026
Purpose: Survival after a cancer diagnosis is improving, increasing the importance of understanding and managing long-term treatment-related adverse effects. This study aimed to understand breast and prostate cancer survivors’ understanding of how cancer treatment may affect cardiovascular and musculoskeletal health. Methods: Australian breast and prostate cancer survivors treated with therapies with known cardiovascular adverse effects were recruited via a private cancer care provider. Participants completed an online background questionnaire, then participated in a focus group. Focus groups were recorded, transcribed, then analysed using reflexive thematic analysis. Results: In total, 26 cancer survivors (15 breast, 11 prostate; mean age 67 years) …
Molecular Landscape Of Sex- And Modality-Specific Exercise Adaptation In Human Skeletal Muscle Through Large-Scale Multi-Omics Integration, Macsue Jacques, Shanie Landen, Adam P. Sharples, Andrew Garnham, Ralf Schittenhelm, Joel Steele, Aino Heikkinen, Elina Sillanpää, Miina Ollikainen, James Broatch, Navabeh Zarekookandeh, Ola Hanson, Ola Ekström, Olof Asplund, Séverine Lamon, Sarah E. Alexander, Cassandra Smith, Carlie Bauer, Mary N. Woessner, Itamar Levinger, Andrew E. Teschendorff, Linn Gillberg, Ida Blom, Jørn Wulff Helge, Nicholas Harvey, Larisa M. Haupt
Molecular Landscape Of Sex- And Modality-Specific Exercise Adaptation In Human Skeletal Muscle Through Large-Scale Multi-Omics Integration, Macsue Jacques, Shanie Landen, Adam P. Sharples, Andrew Garnham, Ralf Schittenhelm, Joel Steele, Aino Heikkinen, Elina Sillanpää, Miina Ollikainen, James Broatch, Navabeh Zarekookandeh, Ola Hanson, Ola Ekström, Olof Asplund, Séverine Lamon, Sarah E. Alexander, Cassandra Smith, Carlie Bauer, Mary N. Woessner, Itamar Levinger, Andrew E. Teschendorff, Linn Gillberg, Ida Blom, Jørn Wulff Helge, Nicholas Harvey, Larisa M. Haupt
Research outputs 2022 to 2026
We investigated the molecular mechanisms of exercise adaptations in human muscle by integrating genome, methylome, transcriptome, and proteome data from over 1,000 participants (2,340 muscle samples). We identified distinctive signatures associated with maximal oxygen consumption (VO2max), and multi-omics integration uncovered five key genes as robust exercise markers across layers, with transcription factors functioning as activators, synergizing with DNA methylation to regulate gene expression. Minimal sex differences were observed, while modality-specific analysis highlighted distinct pathways for aerobic and resistance exercise, contrasting with muscle disuse patterns. Finally, we created a webtool, OMAx, featuring our individual omics and integration analysis. These findings provide …
Implementation And Effectiveness Of A Nurse-Enabled, Shared-Care Follow-Up Model For Early Breast Cancer Survivors (The Ibis-Survivorship Study): Protocol For A Stepped-Wedge Cluster Randomised Trial, Raymond J. Chan, Fiona Crawford-Williams, Bogda Koczwara, G. Bruce Mann, Elizabeth Eakin, Jane Turner, Meinir Krishnasamy, Louisa G. Collins, Helen Skerman, Karla Hemming, Nicolas H. Hart, Jon Emery, Bethany Crowe, Kerry Patford, Jane Mahony, Caroline Kristunas, Gillian Blanchard, Laura Healey, Jasotha Sanmugarajah, Rhea Liang, Paul Craft, Amy Shorthouse, Ruth Mccaffery, Mary Azer, Patsy Yates
Implementation And Effectiveness Of A Nurse-Enabled, Shared-Care Follow-Up Model For Early Breast Cancer Survivors (The Ibis-Survivorship Study): Protocol For A Stepped-Wedge Cluster Randomised Trial, Raymond J. Chan, Fiona Crawford-Williams, Bogda Koczwara, G. Bruce Mann, Elizabeth Eakin, Jane Turner, Meinir Krishnasamy, Louisa G. Collins, Helen Skerman, Karla Hemming, Nicolas H. Hart, Jon Emery, Bethany Crowe, Kerry Patford, Jane Mahony, Caroline Kristunas, Gillian Blanchard, Laura Healey, Jasotha Sanmugarajah, Rhea Liang, Paul Craft, Amy Shorthouse, Ruth Mccaffery, Mary Azer, Patsy Yates
Research outputs 2022 to 2026
Introduction Breast cancer is the most commonly diagnosed cancer among women worldwide. Survivors often experience physical and psychological effects arising from breast cancer and its treatment, which can last months and years, adversely impacting quality of life. As the number of early breast cancer survivors increases, models of specialist-led follow-up care in hospital settings are not sustainable and evidence suggests that they may not meet survivors’ needs. Nurse-enabled, shared-care, follow-up models between cancer specialist and primary care teams have potential to address this need. Methods and analysis The proposed research is a multicentre, prospective, pragmatic, stepped-wedge cluster-randomised trial designed to …
Evaluation Of The Wound Healing And Anti-Microbial Activity Of Hydroethanolic Extracts Of Young And Old Leaves Of Vernonia Amygdalina Delile, Du-Bois Asante, Christian Kweku Adokoh, Elvis Ofori Ameyaw, Desmond Omane Acheampong, Ebenezer Afrifa-Yamoah, Precious Barnes, Gideon Agyeah, Ruben Phillips, Julie Sartori
Evaluation Of The Wound Healing And Anti-Microbial Activity Of Hydroethanolic Extracts Of Young And Old Leaves Of Vernonia Amygdalina Delile, Du-Bois Asante, Christian Kweku Adokoh, Elvis Ofori Ameyaw, Desmond Omane Acheampong, Ebenezer Afrifa-Yamoah, Precious Barnes, Gideon Agyeah, Ruben Phillips, Julie Sartori
Research outputs 2022 to 2026
Background: Vernonia amygdalina Delile (VA) has been reported as an important herb for the management of wound in traditional medical settings. However, the evaluation of the wound healing and antimicrobial effect of the young and old leaves of VA is lacking. Objective This study sought to determine the cutaneous wound healing and in vitro anti-microbial activities of the young and old leaf extracts of VA. Methods Mineral elements that aid in wound healing and vitamin C levels were evaluated in the young and old leaves of VA. Phytochemical analysis of the hydroethanolic leaf extracts of the young leaves (HEthYL) and …
Source-Specific Nitrate And Nitrite Intake And Association With Colorectal Cancer In The Danish Diet, Cancer And Health Cohort, Dorit W. Erichsen, Nicola P. Bondonno, Pratik R. Pokharel, Susanne M. Rosthoj, Catherine P. Bondonno, Liezhou M. Zhong, Jorg Schullehner, Torben L. Sigsgaard, Peter Fjeldstad Hendriksen, Frederik Dalgaard, Ole Raaschou-Nielsen, Jonathan M. Hodgson, Christina C. Dahm, Anja Olsen, Anne Tjonneland, Cecilie Kyro
Source-Specific Nitrate And Nitrite Intake And Association With Colorectal Cancer In The Danish Diet, Cancer And Health Cohort, Dorit W. Erichsen, Nicola P. Bondonno, Pratik R. Pokharel, Susanne M. Rosthoj, Catherine P. Bondonno, Liezhou M. Zhong, Jorg Schullehner, Torben L. Sigsgaard, Peter Fjeldstad Hendriksen, Frederik Dalgaard, Ole Raaschou-Nielsen, Jonathan M. Hodgson, Christina C. Dahm, Anja Olsen, Anne Tjonneland, Cecilie Kyro
Research outputs 2022 to 2026
Introduction: Nitrate and nitrite, present in food and drinking water, may contribute to colorectal cancer (CRC) through the formation of carcinogenic N-nitroso compounds (NOCs). This study examined source-specific associations with CRC and subtypes, considering potential dietary and lifestyle factors that influence NOC formation. Methods: In the Danish Diet, Cancer, and Health Cohort (N=54,610), nitrate/nitrite intake was estimated from comprehensive databases and national monitoring data. Over 27 years, 2245 CRC cases (1508 colon and 737 rectal) were identified via the Danish Cancer Registry. Cox proportional hazards models adjusted for sociodemographic, diet, and lifestyle factors were used to examine associations, with stratified …
Review Of Bronchiectasis Among Aboriginal And Torres Strait Islander Children And Young People (0-18 Years Old), André Schultz, Anne Chang
Review Of Bronchiectasis Among Aboriginal And Torres Strait Islander Children And Young People (0-18 Years Old), André Schultz, Anne Chang
Journal of the Australian Indigenous HealthInfoNet
Bronchiectasis is a chronic lung disease that often commences during childhood. The disease is often under-recognised but can have a significant lifelong impact and shorten survival. This review discussed bronchiectasis in the context of Aboriginal and Torres Strait Islander children and young people. The review includes section on disease prevalence, risk- and protective factors, prevention diagnosis and treatment, the role of the health system, government initiatives and future directions.
Working With Patients Who Self-Injure: An Open Label Study Of An Educational Intervention To Upskill Emergency Nurses On Non-Suicidal Self-Injury, Penelope Hasking, Amanda Aiyana, Jonathon Burcham, Samantha Carey, Joanne M. Dickson, Daniel Fatovich, Logan Hopkins, Eme John, Shirley Mcgough, Chloe Mclean, Irene Ngune, Alex Wheeler
Working With Patients Who Self-Injure: An Open Label Study Of An Educational Intervention To Upskill Emergency Nurses On Non-Suicidal Self-Injury, Penelope Hasking, Amanda Aiyana, Jonathon Burcham, Samantha Carey, Joanne M. Dickson, Daniel Fatovich, Logan Hopkins, Eme John, Shirley Mcgough, Chloe Mclean, Irene Ngune, Alex Wheeler
Research outputs 2022 to 2026
Non-suicidal self-injury (NSSI), deliberate damage to body tissue with no intent to die, is not engaged with suicidal intent but is the most reliable predictor of later suicidal behaviour. This makes efforts to reduce self-injury critical. Emergency departments can be the gateways to care for many people who have self-injured and optimal sites for interventions that promote recovery. However, emergency nurses have anecdotally reported that they lack training and feel ill-equipped to provide care for patients who self-injure. In this open label trial (where both participants and researchers were aware who received the intervention), all nurses in a metropolitan emergency …
Effect Of Relative Isometric Strength On Countermovement Jump Performance In Professional And Semi-Professional Soccer Players, Nicholas Joel Ripley, Jack Fahey, Nabil Hassim, Paul Comfort
Effect Of Relative Isometric Strength On Countermovement Jump Performance In Professional And Semi-Professional Soccer Players, Nicholas Joel Ripley, Jack Fahey, Nabil Hassim, Paul Comfort
Research outputs 2022 to 2026
As powerful actions commonly proceed goal scoring opportunities within soccer, enhancing powerful actions could be essential to optimize performance. There is a large body of evidence supporting the positive associations between maximal isometric mid-thigh pull force-generating qualities and jump performance. Objectives: The purpose of this study was to determine if relative maximal isometric force production can discriminate between higher- and lower-performing jumpers among professional and semi-professional soccer players. As such, it was hypothesized that stronger players would have a greater jump performance than weaker players. Methods: An observational cross-sectional research design was used to assess ballistic and isometric force production …
Longitudinal Associations Between Self-Reported Exercise Levels And Cognition In Adad, Kelsey R. Sewell, James D. Doecke, Ralph N. Martins, Stephanie R. Rainey-Smith, Jeremiah Peiffer, Samantha L. Gardener, Hamid R. Sohrabi, Kirk I. Erickson, Belinda M. Brown
Longitudinal Associations Between Self-Reported Exercise Levels And Cognition In Adad, Kelsey R. Sewell, James D. Doecke, Ralph N. Martins, Stephanie R. Rainey-Smith, Jeremiah Peiffer, Samantha L. Gardener, Hamid R. Sohrabi, Kirk I. Erickson, Belinda M. Brown
Research outputs 2022 to 2026
Introduction: This study examined longitudinal associations between self-reported exercise and cognition, with moderation by sex, in individuals with autosomal dominant Alzheimer's disease (ADAD) mutations. We also examined whether changes in exercise over time differed in ADAD mutation carriers versus non-carriers in the years preceding first cognitive symptom onset. Methods: Participants (n = 491) were ADAD mutation carriers (63%) and non-carriers (37%) from the Dominantly Inherited Alzheimer Network aged 37.6 ± 11.1 years. Participants reported their average time partaking in various leisure-time exercise activities over the past 12 months. Results: Greater baseline exercise predicted better longitudinal cognitive performance. Sex did not …
A Scoping Review On The Integration Of Artificial Intelligence In Point-Of-Care Ultrasound: Current Clinical Applications, Junu Kim, Sandhya Maranna, Caterina Watson, Nayana Parange
A Scoping Review On The Integration Of Artificial Intelligence In Point-Of-Care Ultrasound: Current Clinical Applications, Junu Kim, Sandhya Maranna, Caterina Watson, Nayana Parange
Research outputs 2022 to 2026
Background: Artificial intelligence (AI) is used increasingly in point-of-care ultrasound (POCUS). However, the true role, utility, advantages, and limitations of AI tools in POCUS have been poorly understood. Aim: to conduct a scoping review on the current literature of AI in POCUS to identify (1) how AI is being applied in POCUS, and (2) how AI in POCUS could be utilized in clinical settings. Methods: The review followed the JBI scoping review methodology. A search strategy was conducted in Medline, Embase, Emcare, Scopus, Web of Science, Google Scholar, and AI POCUS manufacturer websites. Selection criteria, evidence screening, and selection were …
Development And Validation Of Competencies For Home-Based Nursing Care: An E-Delphi Study, Khairul Dzakirin Bin Rusli, Ying Lau, Siew Tiang Lau, Laura Schmidt Tham, Michelle Mong Nee Kee, Qi Wen Ng, Shu Fen Ong, Karen Strickland, Sok Ying Liaw
Development And Validation Of Competencies For Home-Based Nursing Care: An E-Delphi Study, Khairul Dzakirin Bin Rusli, Ying Lau, Siew Tiang Lau, Laura Schmidt Tham, Michelle Mong Nee Kee, Qi Wen Ng, Shu Fen Ong, Karen Strickland, Sok Ying Liaw
Research outputs 2022 to 2026
Background: The expected competencies of nurses in home-based care remain unclear. A list of professional competencies that are agreed upon by a panel of content expert are needed to offer some form of standardized expectations among nurses and home-based care stakeholders. Objectives: To evaluate the content validity of the professional competencies identified for home-based nursing care. Design: An e-Delphi method was used. Settings: A purposive sampling of local and international experts in home-based nursing care or community nursing. Methods: Preliminary competency items were developed inductively from earlier studies and deductively by a steering committee. Sixteen experts performed two rounds of …
Consumers' Perspectives On The Design Of A New Digital Frailty Education Course, ‘Focus On Frailty’: A Qualitative Co-Design Study, Kristiana Ludlow, Benignus Logan, Jhalak Arora, Sarah Martin, Elizabeth Miller, Ruth E. Hubbard, Nicola Warren, Olivia Gallagher, Rosemary Saunders
Consumers' Perspectives On The Design Of A New Digital Frailty Education Course, ‘Focus On Frailty’: A Qualitative Co-Design Study, Kristiana Ludlow, Benignus Logan, Jhalak Arora, Sarah Martin, Elizabeth Miller, Ruth E. Hubbard, Nicola Warren, Olivia Gallagher, Rosemary Saunders
Research outputs 2022 to 2026
Introduction: Frailty-focused care in hospitals is hindered by systemic barriers, ageism and stereotypes about older adults and frailty. There is a need for frailty education to increase healthcare professionals' and students' understanding of frailty. Objective: As part of a larger study to co-design a new digital frailty education course, ‘Focus on Frailty’, this study aimed to explore consumers' and caregivers' perspectives on (i) how frailty and older adults should be represented in frailty education and (ii) what healthcare professionals should be taught about caring for older adults and people who are frail in hospitals. Design: This was a qualitative co-design …
Support Networks And Care Needs: Insights From Older Vietnam-Born Australians Living With Chronic Disease, Thi Ngoc Minh Nguyen, Rosemary Saunders, Gordana Dermody, Lisa Whitehead
Support Networks And Care Needs: Insights From Older Vietnam-Born Australians Living With Chronic Disease, Thi Ngoc Minh Nguyen, Rosemary Saunders, Gordana Dermody, Lisa Whitehead
Research outputs 2022 to 2026
This study explored the support networks and care needs of older Vietnam-born adults living in Australia, using focused ethnography, and guided by Leininger's Culture Care theory. Data were collected through participant observation and in-depth interviews over 7 months in Perth, Western Australia, and analyzed thematically. Twelve participants were included. Two themes emerged: “The collectivist context of disease management” and “When in Rome, do as the Romans do.” Chronic disease self-management primarily took place within family and community settings, with ethnic communities playing a significant role. Migration-related stigma influenced perceived care needs, creating a gap between perceived and actual support. Findings …
The Specialist Dementia Care Program In Australia: Evidence To Date On A Home-Like Model Of Care For People With Very Severe Behaviours And Psychological Symptoms Of Dementia, Mustafa Atee, Srivalli Vilapakkam Nagarajan, Rebecca Lloyd, Stephen Macfarlane, Angela Raguz, Thomas Morris
The Specialist Dementia Care Program In Australia: Evidence To Date On A Home-Like Model Of Care For People With Very Severe Behaviours And Psychological Symptoms Of Dementia, Mustafa Atee, Srivalli Vilapakkam Nagarajan, Rebecca Lloyd, Stephen Macfarlane, Angela Raguz, Thomas Morris
Research outputs 2022 to 2026
Objectives: Behaviours and psychological symptoms of dementia (BPSD) have a serious impact on care and health outcomes, such as inappropriate pharmacotherapy and impaired quality of life. These symptoms are common across care settings but are more prevalent in residential aged care homes (RACHs). BPSD such as aggression and psychosis may pose a high risk of harm to residents, co-residents, caregivers and families, and the severe forms of these BPSD are linked to RACH premature admission. When people with very severe BPSD in Australia cannot be cared for in mainstream RACHs, the Specialist Dementia Care Program (SDCP) is offered. This article …
Baseline Habitual Dietary Nitrate Intake And Alzheimer's Disease Related Neuroimaging Biomarkers In The Australian Imaging, Biomarkers And Lifestyle Study Of Ageing, Anjana Rajendra, Nicola P. Bondonno, Kevin Murray, Liezhou Zhong, Stephanie R. Rainey-Smith, Samantha L. Gardener, Lauren C. Blekkenhorst, Vincent Doré, Victor L. Villemagne, Simon M. Laws, Belinda M. Brown, Kevin Taddei, Colin L. Masters, Christopher C. Rowe, Ralph N. Martins, Jonathan M. Hodgson, Catherine P. Bondonno
Baseline Habitual Dietary Nitrate Intake And Alzheimer's Disease Related Neuroimaging Biomarkers In The Australian Imaging, Biomarkers And Lifestyle Study Of Ageing, Anjana Rajendra, Nicola P. Bondonno, Kevin Murray, Liezhou Zhong, Stephanie R. Rainey-Smith, Samantha L. Gardener, Lauren C. Blekkenhorst, Vincent Doré, Victor L. Villemagne, Simon M. Laws, Belinda M. Brown, Kevin Taddei, Colin L. Masters, Christopher C. Rowe, Ralph N. Martins, Jonathan M. Hodgson, Catherine P. Bondonno
Research outputs 2022 to 2026
Background: Dietary nitrate, as a nitric oxide (NO) precursor, may support brain health and protect against dementia. Objective: Our primary aim was to investigate whether dietary nitrate is associated with neuroimaging markers of brain health linked with Alzheimer's disease (AD). Participants: Study participants were cognitively unimpaired individuals from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing (AIBL) who had β-amyloid positron emission tomography (PET) scans (n = 554) and magnetic resonance imaging (MRI) scans (n = 335) and had completed a Food Frequency Questionnaire at baseline. Methods: Source-specific nitrate intakes were estimated using comprehensive nitrate food composition databases. Rates …
Development And Feasibility Of A Driving Training Program For Autistic Student Drivers, Priscilla Vindin, Reinie Cordier, Nathan J. Wilson, Lauren Parsons, Hoe Lee
Development And Feasibility Of A Driving Training Program For Autistic Student Drivers, Priscilla Vindin, Reinie Cordier, Nathan J. Wilson, Lauren Parsons, Hoe Lee
Research outputs 2022 to 2026
Driving licencing rates remain lower for autistic individuals capable of driving a motor vehicle, which can limit achieving independence in community mobility. However, there is limited autism-specific guidance in current driver training. The development and evaluation of the feasibility of an autism-specific Driving Training Program (DTP) intervention was conducted to improve the likelihood that autistic student drivers will safely and successfully learn to drive a motor vehicle and gain a driver’s licence. The DTP intervention was developed using a modified stepped approach for developing complex skills-based interventions. The Goals for Driving Education framework for explaining driving training behaviour modification formed …
Finger Orthoses For Rehabilitation―Part I: Biomedical Insights And Additive Manufacturing Innovations, Alireza Nouri, Lijing Wang, Hamed Bakhtiari, Yuncang Li, Cuie Wen
Finger Orthoses For Rehabilitation―Part I: Biomedical Insights And Additive Manufacturing Innovations, Alireza Nouri, Lijing Wang, Hamed Bakhtiari, Yuncang Li, Cuie Wen
Research outputs 2022 to 2026
Background: Finger orthoses are essential for treating injuries, deformities, and disorders of the upper limbs by supporting, immobilizing, or correcting deformities. Recent advances in three-dimensional (3D) printing have significantly enhanced precision and customization compared to traditional fabrication methods such as thermoplastic molding, plaster or fiberglass casting, and the use of prefabricated splints. Methods: The present review was conducted using PubMed, Scopus, and other databases with keywords such as “hand therapy”, “additive manufacturing”, “finger and thumb”, and “orthosis”. Only English-language publications were considered, with a primary focus on articles published between 2010 and 2025. Key themes were identified and categorized into …
Performance In Multi-Joint Force-Plate Assessments In Male And Female Crossfit® Athletes, James R. Jowsey, G. Gregory Haff, Paul Comfort, Nicholas Joel Ripley
Performance In Multi-Joint Force-Plate Assessments In Male And Female Crossfit® Athletes, James R. Jowsey, G. Gregory Haff, Paul Comfort, Nicholas Joel Ripley
Research outputs 2022 to 2026
Background: CrossFit® aims to be equitable between both males and female athletes, supporting equal representation and equal prize money at international events. However, to date, limited information is known on CrossFit® athletes’ performance in the countermovement jump (CMJ), countermovement rebound jump (CMR-J), and isometric mid-thigh pull (IMTP) when assessed using force plates, and if there are any differences between sexes. Therefore, the purpose of the present study was to observe whether any sex-based differences and relationships exist between performance within these assessments. Methods: A total of CrossFit athletes (43 male = 32.8 ± 9.0 years; height 1.78 ± …
Pre-Amplification Of Cell-Free Dna: Balancing Amplification Errors With Enhanced Sensitivity, Wei Yen Chan, Ashleigh Stewart, Russell J. Diefenbach, Elin S. Gray, Jenny H. Lee, Richard A. Scolyer, Georgina V. Long, Helen Rizos
Pre-Amplification Of Cell-Free Dna: Balancing Amplification Errors With Enhanced Sensitivity, Wei Yen Chan, Ashleigh Stewart, Russell J. Diefenbach, Elin S. Gray, Jenny H. Lee, Richard A. Scolyer, Georgina V. Long, Helen Rizos
Research outputs 2022 to 2026
Circulating tumour DNA (ctDNA) is a promising biomarker for personalised oncology. However, its clinical utility is limited by detection sensitivity, particularly in early-stage disease. T-Oligo Primed Polymerase Chain Reaction (TOP-PCR) is a commercial amplification approach utilising an efficient “half-adapter” ligation design and a single-primer-based PCR strategy. This study evaluated the clinical value and application of cell-free DNA (cfDNA) pre-amplification. cfDNA amplification with TOP-PCR preserved DNA size profiles and resulted in a 22 bp size increase due to the half-adaptor ligation. Gene target amplification rates varied, showing lower efficiency for the GC-rich TERT promoter amplicon and higher efficiency for the BRAF …