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Articles 2971 - 3000 of 4977
Full-Text Articles in Medicine and Health Sciences
A Quest For Quality Care: Exploration Of A Model Of Leadership Relationships, Work Engagement, And Patient Outcomes, Jenny M. Parr, Stephen Teo, Jane Koziol-Mclain
A Quest For Quality Care: Exploration Of A Model Of Leadership Relationships, Work Engagement, And Patient Outcomes, Jenny M. Parr, Stephen Teo, Jane Koziol-Mclain
Research outputs 2014 to 2021
© 2020 The Authors. Journal of Advanced Nursing published by John Wiley & Sons Ltd Aim: To explore the effects of resonant leadership, leader exchange relationships and perceived organizational support on work engagement and patient outcomes. Design: A cross-sectional survey design. Methods: Data were collected in June and July 2016 from 252 nurses and clerical staff and institutional patient safety (falls rates) and patient satisfaction (Friends and Family Test) in New Zealand. Data were analysed with structural equation modelling (SEM). Results: The final model was an excellent fit to the data (χ2 (22, N = 252) = 39.048, p = …
Tripping Over The Other: Could Psychedelics Increase Empathy?, Emily Blatchford, Stephen Bright, Liam Engel
Tripping Over The Other: Could Psychedelics Increase Empathy?, Emily Blatchford, Stephen Bright, Liam Engel
Research outputs 2014 to 2021
There is increasing evidence that psychedelic-assisted psychotherapy is effective for a range of psy-chological conditions. There are likely numerous mechanisms of action that contribute to these clinicaleffects. One such mechanism of action might involve psychedelics increasing levels of empathicfunctioning. This paper synthesises research concerning the relationship between psychedelics andempathy, emphasising neuroscientific and clinical contexts. We conclude that neuropsychological andclinical evidence imply psychedelics could lead to increased empathic functioning. The effects of psy-chedelics on the 5-HT system, default mode network, neural connectivity and ego dissolution areimplicated in these changes. Changes in empathic functioning also likely relate to increases in thepersonality trait …
Summary Of Nutrition Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet
Summary Of Nutrition Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet
Research outputs 2014 to 2021
No abstract provided.
Should The Pbl Tutor Be Present? A Cross-Sectional Study Of Group Effectiveness In Synchronous And Asynchronous Settings, Samuel Edelbring, Siw Alehagen, Evalotte Mörelius, Annakarin Johansson, Patrik Rytterström
Should The Pbl Tutor Be Present? A Cross-Sectional Study Of Group Effectiveness In Synchronous And Asynchronous Settings, Samuel Edelbring, Siw Alehagen, Evalotte Mörelius, Annakarin Johansson, Patrik Rytterström
Research outputs 2014 to 2021
Background: The tutorial group and its dynamics are a cornerstone of problem-based learning (PBL). The tutor's support varies according to the setting, and it is pertinent to explore group effectiveness in relation to different settings, for example online or campus-based. The PBL groups' effectiveness can partly be assessed in terms of cognitive and motivational aspects, using a self-report tool to measure PBL group effectiveness, the Tutorial Group Effectiveness Instrument (TGEI). This study's aim was to explore tutor participation in variations of online and campus-based tutorial groups in relation to group effectiveness. A secondary aim was to validate a tool for …
The Effect Of Sleep Restriction, With Or Without High-Intensity Interval Exercise, On Myofibrillar Protein Synthesis In Healthy Young Men, Nicholas J. Saner, Matthew J. -C. Lee, Nathan W. Pitchford, Jujiao Kuang, Gregory D. Roach, Andrew Garnham, Tanner Stokes, Stuart M. Phillips, David J. Bishop, Jonathan D. Bartlett
The Effect Of Sleep Restriction, With Or Without High-Intensity Interval Exercise, On Myofibrillar Protein Synthesis In Healthy Young Men, Nicholas J. Saner, Matthew J. -C. Lee, Nathan W. Pitchford, Jujiao Kuang, Gregory D. Roach, Andrew Garnham, Tanner Stokes, Stuart M. Phillips, David J. Bishop, Jonathan D. Bartlett
Research outputs 2014 to 2021
Key points: Sleep restriction has previously been associated with the loss of muscle mass in both human and animal models. The rate of myofibrillar protein synthesis (MyoPS) is a key variable in regulating skeletal muscle mass and can be increased by performing high-intensity interval exercise (HIIE), although the effect of sleep restriction on MyoPS is unknown. In the present study, we demonstrate that participants undergoing a sleep restriction protocol (five nights, with 4 h in bed each night) had lower rates of skeletal muscle MyoPS; however, rates of MyoPS were maintained at control levels by performing HIIE during this period. …
Randomised Placebo-Controlled Cross-Over Study Examining The Role Of Anamorelin In Mesothelioma (The Anthem Study): Rationale And Protocol, Siao Nge Hoon, Katrina Fyfe, Carolyn J. Peddle-Mcintyre, Samantha Bowyer, Felicity Hawkins, Emily Jeffery, Hui Jun Chih, Jenette Creaney, Anna Nowak, Fraser Brims
Randomised Placebo-Controlled Cross-Over Study Examining The Role Of Anamorelin In Mesothelioma (The Anthem Study): Rationale And Protocol, Siao Nge Hoon, Katrina Fyfe, Carolyn J. Peddle-Mcintyre, Samantha Bowyer, Felicity Hawkins, Emily Jeffery, Hui Jun Chih, Jenette Creaney, Anna Nowak, Fraser Brims
Research outputs 2014 to 2021
Introduction Cachexia is common in malignant mesothelioma (MM); half of patients have malnutrition and low skeletal muscle mass. Malnourished patients have worse quality of life (QoL). Weight loss is strongly associated with poor survival. Anamorelin is an oral ghrelin receptor agonist that improves appetite, body weight and QoL in advanced cancer. The aim of this study is to examine the efficacy of anamorelin in improving appendicular skeletal muscle mass (ASM) and patient-reported outcomes in patients with MM with cachexia. Methods and analysis A single-centre, phase II, randomised, placebo-controlled cross-over pilot study with 28-day treatment periods and 3-day washout. Forty patients …
Definitions, Sources And Self-Reported Consumption Of Regionally Grown Fruits And Vegetables In Two Regions Of Australia, Katherine Kent, Stephanie Godrich, Sandra Murray, Stuart Auckland, Lauren Blekkenhorst, Beth Penrose, Johnny Lo, Amanda Devine
Definitions, Sources And Self-Reported Consumption Of Regionally Grown Fruits And Vegetables In Two Regions Of Australia, Katherine Kent, Stephanie Godrich, Sandra Murray, Stuart Auckland, Lauren Blekkenhorst, Beth Penrose, Johnny Lo, Amanda Devine
Research outputs 2014 to 2021
Regional food systems are complex networks, with numerous retail sources that underpin a local economy. However, evidence is limited regarding how consumers define, identify, and source regionally grown fresh fruits and vegetables (RGFFV). A cross-sectional study was conducted in Tasmania (TAS) and South Western Australia (SWA) to compare how RGFFV are defined, identified and sourced by consumers, including self-reported consumption of selected RGFFV. Survey data were analyzed using the Chi-square test and t-tests. Results (TAS n = 120, SWA n = 123) identified that consumers had mixed perceptions of how RGFFV are defined, including produce sold at farmers markets, or …
The Relationship Between Physical Activity, Apolipoprotein E Ε4 Carriage, And Brain Health, Jaisalmer De Frutos-Lucas, Pablo Cuesta, David López-Sanz, Africa Peral-Suárez, Esther Cuadrado-Soto, Federico Ramírez-Toraño, Belinda M. Brown, Juan M. Serrano, Simon M. Laws, Inmaculada C. Rodríguez-Rojo, Juan Verdejo-Román, Ricardo Bruña, Maria L. Delgado-Losada, Ana Barabash, Ana M. López-Sobaler, Ramon López-Higes, Alberto Marcos, Fernando Maestú
The Relationship Between Physical Activity, Apolipoprotein E Ε4 Carriage, And Brain Health, Jaisalmer De Frutos-Lucas, Pablo Cuesta, David López-Sanz, Africa Peral-Suárez, Esther Cuadrado-Soto, Federico Ramírez-Toraño, Belinda M. Brown, Juan M. Serrano, Simon M. Laws, Inmaculada C. Rodríguez-Rojo, Juan Verdejo-Román, Ricardo Bruña, Maria L. Delgado-Losada, Ana Barabash, Ana M. López-Sobaler, Ramon López-Higes, Alberto Marcos, Fernando Maestú
Research outputs 2014 to 2021
BACKGROUND: Neuronal hyperexcitability and hypersynchrony have been described as key features of neurophysiological dysfunctions in the Alzheimer's disease (AD) continuum. Conversely, physical activity (PA) has been associated with improved brain health and reduced AD risk. However, there is controversy regarding whether AD genetic risk (in terms of APOE ε4 carriage) modulates these relationships. The utilization of multiple outcome measures within one sample may strengthen our understanding of this complex phenomenon. METHOD: The relationship between PA and functional connectivity (FC) was examined in a sample of 107 healthy older adults using magnetoencephalography. Additionally, we explored whether ε4 carriage modulates this association. …
A Rapid Absorbance-Based Growth Assay To Screen The Toxicity Of Oligomer Aβ42 And Protect Against Cell Death In Yeast, Prashant Bharadwaj, Ralph Martins
A Rapid Absorbance-Based Growth Assay To Screen The Toxicity Of Oligomer Aβ42 And Protect Against Cell Death In Yeast, Prashant Bharadwaj, Ralph Martins
Research outputs 2014 to 2021
Multiple lines of evidence show that soluble oligomer forms of amyloid β protein (Aβ42) are the most neurotoxic species in the brain and correlates with the degree of neuronal loss and cognitive deficit in Alzheimer's disease. Although many studies have used mammalian cells to investigate oligomer Aβ42 toxicity, the use of more simple eukaryotic cellular systems offers advantages for large-scale screening studies. We have previously established and validated budding yeast, Saccharomyces cerevisiae to be a simple and a robust model to study the toxicity of Aβ. Using colony counting based methods, oligomeric Aβ42 was shown to induce dose-dependent cell death …
Limitations Of The Digestible Indispensable Amino Acid Score (Diaas) And Choice Of Statistical Reporting. Comment On “A Comparison Of Dietary Protein Digestibility, Based On Diaas Scoring, In Vegetarian And Non-Vegetarian Athletes. Nutrients 2019, 11, 3106”, Angela Genoni, Joel C. Craddock, Emma Strutt
Limitations Of The Digestible Indispensable Amino Acid Score (Diaas) And Choice Of Statistical Reporting. Comment On “A Comparison Of Dietary Protein Digestibility, Based On Diaas Scoring, In Vegetarian And Non-Vegetarian Athletes. Nutrients 2019, 11, 3106”, Angela Genoni, Joel C. Craddock, Emma Strutt
Research outputs 2014 to 2021
No abstract provided.
The Role Of Virtual Reality In Improving Health Outcomes For Community-Dwelling Older Adults: A Systematic Review, Gordana Dermody, Lisa Whitehead, Graham Wilson, Courtney Glass
The Role Of Virtual Reality In Improving Health Outcomes For Community-Dwelling Older Adults: A Systematic Review, Gordana Dermody, Lisa Whitehead, Graham Wilson, Courtney Glass
Research outputs 2014 to 2021
Background:
Virtual reality (VR) delivered through immersive headsets creates an opportunity to deliver interventions to improve physical, mental, and psychosocial health outcomes. VR app studies with older adults have primarily focused on rehabilitation and physical function including gait, balance, fall prevention, pain management, and cognition. Several systematic reviews have previously been conducted, but much of the extant literature is focused on rehabilitation or other institutional settings, and little is known about the effectiveness of VR apps using immersive headsets to target health outcomes among community-dwelling older adults.
Objective:
The objective of this review was to evaluate the effectiveness of VR …
A Randomised Controlled Crossover Trial Investigating The Short-Term Effects Of Different Types Of Vegetables On Vascular And Metabolic Function In Middle-Aged And Older Adults With Mildly Elevated Blood Pressure: The Vegetables For Vascular Health (Vessel) Study Protocol, Emma Connolly, Catherine P. Bondonno, Marc Sim, Simone Radavelli-Bagatini, Kevin D. Croft, Mary C. Boyce, Anthony P. James, Karin Clark, Reindolf Anokye, Nicola P. Bondonno, Richard Woodman, Amanda Devine, Seng Khee Gan, Carl J. Schultz, Richard F. Mithen, Joshua Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst
A Randomised Controlled Crossover Trial Investigating The Short-Term Effects Of Different Types Of Vegetables On Vascular And Metabolic Function In Middle-Aged And Older Adults With Mildly Elevated Blood Pressure: The Vegetables For Vascular Health (Vessel) Study Protocol, Emma Connolly, Catherine P. Bondonno, Marc Sim, Simone Radavelli-Bagatini, Kevin D. Croft, Mary C. Boyce, Anthony P. James, Karin Clark, Reindolf Anokye, Nicola P. Bondonno, Richard Woodman, Amanda Devine, Seng Khee Gan, Carl J. Schultz, Richard F. Mithen, Joshua Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst
Research outputs 2014 to 2021
A diet rich in fruits and vegetables is recommended for cardiovascular health. However, the majority of Australians do not consume the recommended number of vegetable servings each day. Furthermore, intakes of vegetables considered to have the greatest cardiovascular benefit are often very low. Results from prospective observational studies indicate that a higher consumption of cruciferous vegetables (e.g. broccoli, cabbage, cauliflower) is associated with lower cardiovascular disease risk. This may be due to the presence of specific nutrients and bioactive compounds found almost exclusively, or at relatively high levels, in cruciferous vegetables. Therefore, the aim of this randomised controlled crossover trial …
Summary Of Aboriginal And Torres Strait Islander Health Status 2019, Australian Indigenous Healthinfonet
Summary Of Aboriginal And Torres Strait Islander Health Status 2019, Australian Indigenous Healthinfonet
Research outputs 2014 to 2021
The Summary of Aboriginal and Torres Strait Islander health status 2019 (Summary) provides a brief and current overview of the health of Aboriginal and Torres Strait Islander people in Australia in a plain language and visual style. The Australian Indigenous HealthInfoNet has prepared the Summary as part of our contribution to support those in the Aboriginal and Torres Strait Islander workforce and those participating in research and working with Aboriginal and Torres Strait Islander people and their communities...
Integrating And Maintaining Automated External Defibrillators And Emergency Planning In Community Sport Settings: A Qualitative Case Study, Lauren V. Fortington, Sheree Bekker, Caroline Finch
Integrating And Maintaining Automated External Defibrillators And Emergency Planning In Community Sport Settings: A Qualitative Case Study, Lauren V. Fortington, Sheree Bekker, Caroline Finch
Research outputs 2014 to 2021
Introduction:
A voluntary State Government-led programme in Victoria, Australia ‘Defibrillators for Sporting Clubs and Facilities Program’ ran from 2015 to 2019, broadly aimed at increasing access to automated external defibrillators (AEDs), together with a greater number of community members trained for management of medical emergencies. This study aimed to understand whether participating sport clubs/facilities had successfully integrated an AED and medical planning with other club/facility safety practices, 12 months after delivery of the programme.
Methods:
This was a qualitative case study of 14 sport clubs/facilities in Victoria, Australia in 2017, underpinned by the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework. …
Application Of A Brain-Inspired Spiking Neural Network Architecture To Odor Data Classification, Anup Vanarse, Josafath Israel Espinosa-Ramos, Adam Osseiran, Alexander Rassau, Nikola Kasabov
Application Of A Brain-Inspired Spiking Neural Network Architecture To Odor Data Classification, Anup Vanarse, Josafath Israel Espinosa-Ramos, Adam Osseiran, Alexander Rassau, Nikola Kasabov
Research outputs 2014 to 2021
Existing methods in neuromorphic olfaction mainly focus on implementing the data transformation based on the neurobiological architecture of the olfactory pathway. While the transformation is pivotal for the sparse spike-based representation of odor data, classification techniques based on the bio-computations of the higher brain areas, which process the spiking data for identification of odor, remain largely unexplored. This paper argues that brain-inspired spiking neural networks constitute a promising approach for the next generation of machine intelligence for odor data processing. Inspired by principles of brain information processing, here we propose the first spiking neural network method and associated deep machine …
Objective Quantification Of Burn Scar Stiffness Using Shear-Wave Elastography: Initial Evidence Of Validity, Helen Dejong, Steven Abbott, Marilyn Zelesco, Katrina Spilsbury, Melanie Ziman, Brendan F. Kennedy, Lisa Martin, Fiona M. Wood
Objective Quantification Of Burn Scar Stiffness Using Shear-Wave Elastography: Initial Evidence Of Validity, Helen Dejong, Steven Abbott, Marilyn Zelesco, Katrina Spilsbury, Melanie Ziman, Brendan F. Kennedy, Lisa Martin, Fiona M. Wood
Research outputs 2014 to 2021
Shear-wave elastography (SWE) is an ultrasound based technology that can provide reliable measurements (velocity) of scar stiffness. The aim of this research was to evaluate the concurrent validity of using both the measured velocity and the calculated difference in velocity between scars and matched controls, in addition to evaluating potential patient factors that may influence the interpretation of the measurements.
Methods
A cross-sectional study of 32 participants, with 48 burn scars and 48 matched contralateral control sites were evaluated with SWE, the Vancouver Scar Scale (VSS) and the Patient and Observer Scar Assessment Scale (POSAS) tactile sub-scores.
Results
Spearman’s rho …
Relationships Between Plasma Lipids Species, Gender, Risk Factors And Alzheimer’S Disease, Wei Ling Florence Lim, Kevin Huynh, Pratishtha Chatterjee, Ian Martins, Kaushala S. Jayawardana, Corey Giles, Natalie A. Mellett, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Brian G. Drew, Colin L. Masters, Peter J. Meikle, Ralph Martins, Australian Imaging, Biomarker & Lifestyle Research Group
Relationships Between Plasma Lipids Species, Gender, Risk Factors And Alzheimer’S Disease, Wei Ling Florence Lim, Kevin Huynh, Pratishtha Chatterjee, Ian Martins, Kaushala S. Jayawardana, Corey Giles, Natalie A. Mellett, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Brian G. Drew, Colin L. Masters, Peter J. Meikle, Ralph Martins, Australian Imaging, Biomarker & Lifestyle Research Group
Research outputs 2014 to 2021
Background:
Lipid metabolism is altered in Alzheimer’s disease (AD); however, the relationship between AD risk factors (age, APOE ɛ4, and gender) and lipid metabolism is not well defined.
Objective:
We investigated whether altered lipid metabolism associated with increased age, gender, and APOE status may contribute to the development of AD by examining these risk factors in healthy controls and also clinically diagnosed AD individuals.
Methods:
We performed plasma lipidomic profiling (582 lipid species) of the Australian Imaging, Biomarkers and Lifestyle flagship study of aging cohort (AIBL) using liquid chromatography-mass spectrometry. Linear regression and interaction analysis were used to explore …
Summary Of Cardiovascular Health Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet
Summary Of Cardiovascular Health Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet
Research outputs 2014 to 2021
This Summary describes different types of cardiovascular disease (CVD) and how common they are among Aboriginal and Torres Strait Islander people. It highlights the differences in how groups of Aboriginal and Torres Strait Islander people – such as women and men, or older and younger people – experience CVD. It describes some improvements in the cardiovascular health of Aboriginal and Torres Strait Islander people. It also gives examples of the many good things that are being done on the ground to prevent illness and improve CVD care for Aboriginal and Torres Strait Islander people.
Development Of A Human Activity Recognition System For Ballet Tasks, Danica Hendry, Kevin Chai, Amity Campbell, Luke Hopper, Peter O'Sullivan, Leon Straker
Development Of A Human Activity Recognition System For Ballet Tasks, Danica Hendry, Kevin Chai, Amity Campbell, Luke Hopper, Peter O'Sullivan, Leon Straker
Research outputs 2014 to 2021
Background Accurate and detailed measurement of a dancer’s training volume is a key requirement to understanding the relationship between a dancer’s pain and training volume. Currently, no system capable of quantifying a dancer’s training volume, with respect to specific movement activities, exists. The application of machine learning models to wearable sensor data for human activity recognition in sport has previously been applied to cricket, tennis and rugby. Thus, the purpose of this study was to develop a human activity recognition system using wearable sensor data to accurately identify key ballet movements (jumping and lifting the leg). Our primary objective was …
The Effects Of Vitamin K-Rich Green Leafy Vegetables On Bone Metabolism: A 4-Week Randomised Controlled Trial In Middle-Aged And Older Individuals, Marc Sim, Joshua R. Lewis, Richard L. Prince, Itamar Levinger, Tara C. Brennan-Speranza, Claire Palmer, Catherine P. Bondonno, Nicola P. Bondonno, Amanda Devine, Natalie C. Ward, Elizabeth Byrnes, Carl J. Schultz, Richard Woodman, Kevin Croft, Jonathan M. Hodgson, Lauren C. Blekkenhorst
The Effects Of Vitamin K-Rich Green Leafy Vegetables On Bone Metabolism: A 4-Week Randomised Controlled Trial In Middle-Aged And Older Individuals, Marc Sim, Joshua R. Lewis, Richard L. Prince, Itamar Levinger, Tara C. Brennan-Speranza, Claire Palmer, Catherine P. Bondonno, Nicola P. Bondonno, Amanda Devine, Natalie C. Ward, Elizabeth Byrnes, Carl J. Schultz, Richard Woodman, Kevin Croft, Jonathan M. Hodgson, Lauren C. Blekkenhorst
Research outputs 2014 to 2021
Background: High vegetable intake is associated with beneficial effects on bone. However, the mechanisms remain uncertain. Green leafy vegetables are a rich source of vitamin K1, which is known to have large effects on osteoblasts and osteocalcin (OC) metabolism. Objective: To examine the effects of consumption of two to three extra serves of green leafy vegetables daily on bone metabolism. Methods: Thirty individuals (mean age 61.8 ± 9.9 years, 67% male) completed three experimental phases in a randomised controlled crossover design, each lasting four weeks, with a washout period of four weeks between phases (clinical trial registration: ACTRN12615000194561). The three …
Cost-Effectiveness Of An Environmental Cleaning Bundle For Reducing Healthcare-Associated Infections, Nicole M. White, Adrian G. Barnett, Lisa Hall, Brett G. Mitchell, Alison Farrington, Kate Halton, David L. Paterson, Thomas V. Riley, Anne Gardner, Katie Page, Christian A. Gericke, Nicolas Graves
Cost-Effectiveness Of An Environmental Cleaning Bundle For Reducing Healthcare-Associated Infections, Nicole M. White, Adrian G. Barnett, Lisa Hall, Brett G. Mitchell, Alison Farrington, Kate Halton, David L. Paterson, Thomas V. Riley, Anne Gardner, Katie Page, Christian A. Gericke, Nicolas Graves
Research outputs 2014 to 2021
Background: Healthcare-associated infections (HAIs) remain a significant patient safety issue, with point prevalence estimates being ~5% in high-income countries. In 2016–2017, the Researching Effective Approaches to Cleaning in Hospitals (REACH) study implemented an environmental cleaning bundle targeting communication, staff training, improved cleaning technique, product use, and audit of frequent touch-point cleaning. This study evaluates the cost-effectiveness of the environmental cleaning bundle for reducing the incidence of HAIs. Methods: A stepped-wedge, cluster-randomized trial was conducted in 11 hospitals recruited from 6 Australian states and territories. Bundle effectiveness was measured by the numbers of Staphylococcus aureus bacteremia, Clostridium difficile infection, and vancomycin-resistant …
Aboriginal People With Chronic Hcv: The Role Of Community Health Nurses For Improving Health-Related Quality Of Life, Amineh Rashidi, Peter Higgs, Susan Carruthers
Aboriginal People With Chronic Hcv: The Role Of Community Health Nurses For Improving Health-Related Quality Of Life, Amineh Rashidi, Peter Higgs, Susan Carruthers
Research outputs 2014 to 2021
Introduction: There is a lack of knowledge about Health-Related Quality of Life (HRQL) of Aboriginal Australians with self-reported hepatitis C infection in Western Australia. This marginalised group of people is disproportionally affected by the hepatitis C virus (HCV) for which there is no preventative vaccine. This study provides data that help understand the long-term consequences of living with HCV infection within the Aboriginal community. It outlines opportunities for nursing interventions for hepatitis care that focus on supporting mental health and drug and alcohol issues within this population. Methods: We surveyed 123 Aboriginal people living with HCV in a community setting. …
Population-Based Case-Control Study Revealed Metabolomic Biomarkers Of Suboptimal Health Status In Chinese Population—Potential Utility For Innovative Approach By Predictive, Preventive, And Personalized Medicine, Hao Wang, Qiuyue Tian, Jie Zhang, Hongqi Liu, Xiaoyu Zhang, Weijie Cao, Jinxia Zhang, Enoch Odame Anto, Xingang Li, Xueqing Wang, Di Liu, Yulu Zheng, Zheng Guo, Lijuan Wu, Manshu Song, Youxin Wang, Wei Wang
Population-Based Case-Control Study Revealed Metabolomic Biomarkers Of Suboptimal Health Status In Chinese Population—Potential Utility For Innovative Approach By Predictive, Preventive, And Personalized Medicine, Hao Wang, Qiuyue Tian, Jie Zhang, Hongqi Liu, Xiaoyu Zhang, Weijie Cao, Jinxia Zhang, Enoch Odame Anto, Xingang Li, Xueqing Wang, Di Liu, Yulu Zheng, Zheng Guo, Lijuan Wu, Manshu Song, Youxin Wang, Wei Wang
Research outputs 2014 to 2021
Background: Suboptimal health status (SHS) is a subclinical stage of chronic diseases, and the identification of SHS provides an opportunity for the predictive, preventive, and personalized medicine (PPPM) of chronic diseases. Previous studies have reported the associations between metabolic signatures and early signs of chronic diseases. Methods: This study aimed to detect the metabolic biomarkers for the identification of SHS in a case-control study. SHS questionnaire-25 (SHSQ-25) was used in a population-based health survey to measure the SHS levels of participants. The liquid chromatography-mass spectrometry-based untargeted metabolomics analysis was conducted on plasma samples collected from 50 SHS participants and 50 …
"Ode To Confidence": Poetry Groups For Dysarthria In Multiple Sclerosis, Rebecca Balchin, Deborah Hersh, Jamaica Grantis, Maddie Godfrey
"Ode To Confidence": Poetry Groups For Dysarthria In Multiple Sclerosis, Rebecca Balchin, Deborah Hersh, Jamaica Grantis, Maddie Godfrey
Research outputs 2014 to 2021
Purpose: Approximately 40–50% of people with multiple sclerosis (MS) have dysarthria impacting confidence in communication. This study explored how people with MS experienced a novel therapeutic approach combining dysarthria therapy with poetry in a group format. Method: Participants were recruited through MSWA (formerly known as the Multiple Sclerosis Society of Western Australia), a leading service provider for people living with all neurological conditions in Western Australia. They attended eight weekly sessions led by a speech pathologist and a professional poet. The study was co-designed and qualitative, using observational field notes recorded during sessions and semi-structured in-depth interviews with participants after …
You Can’T Flight, You Need To Fight – A Qualitative Study Of Mothers’ Experiences Of Feeding Extremely Preterm Infants, Evalotte Morelius, Kajsa Kling, Eva Haraldsson, Siw Alehagen
You Can’T Flight, You Need To Fight – A Qualitative Study Of Mothers’ Experiences Of Feeding Extremely Preterm Infants, Evalotte Morelius, Kajsa Kling, Eva Haraldsson, Siw Alehagen
Research outputs 2014 to 2021
Aim To describe mother's experiences of feeding their extremely preterm infant. Background When an infant is born extremely preterm, there is a long rocky road for the mother if she wants to breastfeed. Some manage to reach their goals, others do not. Studies of feeding extremely preterm infants in the neonatal intensive care unit (NICU) are scarce. Design A qualitative method with an inductive approach. Methods Nine mothers giving birth to extremely preterm infants were interviewed by telephone after discharge from the NICU. The interviews were transcribed verbatim and analysed with qualitative content analysis. The COREQ checklist was followed. Results …
The Rise Of Rapid Implementation: A Worked Example Of Solving An Existing Problem With A New Method By Combining Concept Analysis With A Systematic Integrative Review, James Smith, Frances Rapport, Tracey A. O'Brien, Stephanie Smith, Vanessa J. Tyrrell, Emily V.A Mould, Janet C. Long, Hossai Gul, Jeremy Cullis, Jeffrey Braithwaite
The Rise Of Rapid Implementation: A Worked Example Of Solving An Existing Problem With A New Method By Combining Concept Analysis With A Systematic Integrative Review, James Smith, Frances Rapport, Tracey A. O'Brien, Stephanie Smith, Vanessa J. Tyrrell, Emily V.A Mould, Janet C. Long, Hossai Gul, Jeremy Cullis, Jeffrey Braithwaite
Research outputs 2014 to 2021
Background The concept of rapid implementation has emerged in the literature recently, but without a precise definition. Further exploration is required to distinguish the concept’s unique meanings and significance from the perspective of implementation science. The study clarifies the concept of rapid implementation and identifies its attributes, antecedents, and consequences. We present a theoretical definition of rapid implementation to clarify its unique meaning and characteristics. Methods Rodgers evolutionary concept analysis method, combined with a systematic integrative review, were used to clarify the concept of rapid implementation. A comprehensive search of four databases, including EMBASE, MEDLINE, SCOPUS, and WEB OF SCIENCE …
Is Dietary Vitamin A Associated With Myopia From Adolescence To Young Adulthood?, Fletcher J. Ng, David A. Mackey, Therese A. O'Sullivan, Wendy H. Oddy, Seyhan Yazar
Is Dietary Vitamin A Associated With Myopia From Adolescence To Young Adulthood?, Fletcher J. Ng, David A. Mackey, Therese A. O'Sullivan, Wendy H. Oddy, Seyhan Yazar
Research outputs 2014 to 2021
Purpose: Potential links may exist between vitamin A intake and myopia via various pathways. In this study, we examined the association between dietary vitamin A intake during adolescence and myopia in early adulthood. Methods: We performed a prospective analysis utilizing data collected from participants of the Raine Study Gen2. Dietary vitamin A intake, determined via food frequency questionnaires completed at ages 14, 17, and 20 years, was compared with ophthalmic measurements collected at year 20. Low vitamin A levels were defined as <600 >µg/day. Regression models were used to adjust for ocular sun exposure level, educational level, and parental myopia as …600>
Igg Glycosylation Profile And The Glycan Score Are Associated With Type 2 Diabetes In Independent Chinese Populations: A Case-Control Study, Zhiyuan Wu, Haibin Li, Di Liu, Lixin Tao, Jie Zhang, Baolu Liang, Xiangtong Liu, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo
Igg Glycosylation Profile And The Glycan Score Are Associated With Type 2 Diabetes In Independent Chinese Populations: A Case-Control Study, Zhiyuan Wu, Haibin Li, Di Liu, Lixin Tao, Jie Zhang, Baolu Liang, Xiangtong Liu, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo
Research outputs 2014 to 2021
Background. The relationship between the IgG glycan panel and type 2 diabetes remains unclear in Chinese population. We aimed to investigate the association of the IgG glycan profile and glycan score with type 2 diabetes. Methods. In the discovery population, 162 individuals diagnosed with type 2 diabetes and 162 matched controls from Beijing health management cohort were included. We analyzed the IgG glycan profile and composed a glycan score for type 2 diabetes. Findings were validated in the replication population from Beijing Xuanwu community cohort (280 cases and 508 controls). Area under curve (AUC) using 10-fold and bootstrap validation, net …
Docosahexaenoic Acid-Rich Fish Oil Supplementation Reduces Kinase Associated With Insulin Resistance In Overweight And Obese Midlife Adults, Rohith N. Thota, Jessica I. Rosato, Tracy L. Burrows, Cintia B. Dias, Kylie A. Abbott, Ralph N. Martins, Manohar L. Garg
Docosahexaenoic Acid-Rich Fish Oil Supplementation Reduces Kinase Associated With Insulin Resistance In Overweight And Obese Midlife Adults, Rohith N. Thota, Jessica I. Rosato, Tracy L. Burrows, Cintia B. Dias, Kylie A. Abbott, Ralph N. Martins, Manohar L. Garg
Research outputs 2014 to 2021
Targeting kinases linked to insulin resistance (IR) and inflammation may help in reducing the risk of type 2 diabetes (T2D) and Alzheimer’s disease (AD) in its early stages. This study aimed to determine whether DHA-rich fish oil supplementation reduces glycogen synthase kinase (GSK-3), which is linked to both IR and AD. Baseline and post-intervention plasma samples from 58 adults with abdominal obesity (Age: 51.7 ± 1.7 years, BMI: 31.9 ± 0.8 kg/m2) were analysed for outcome measures. Participants were allocated to 2 g DHA-rich fish oil capsules (860 mg DHA + 120 mg EPA) (n = 31) or placebo capsules …
Absolute And Relative Strength, Power And Physiological Characteristics Of Indian Junior National-Level Judokas, Dale M. Harris, Kristina Kendall, G. Gregory Haff, Christopher Latella
Absolute And Relative Strength, Power And Physiological Characteristics Of Indian Junior National-Level Judokas, Dale M. Harris, Kristina Kendall, G. Gregory Haff, Christopher Latella
Research outputs 2014 to 2021
The physical qualities that underpin successful junior judokas requires continuing investigation. We investigated the physical and physiological characteristics of junior national level judokas. We tested 25 (15 male, 10 female) Indian judokas for absolute and relative strength (back-squat and bench-press one-repetition maximum (1RM) as well as isometric handgrip), aerobic (RAMP test) and lower-body anaerobic power (Wingate 6-s sprint and countermovement jump), change-of-direction (5-0-5 test) and speed (30 m sprint). Athletes were grouped according to national-level competition placing (gold-medal winners (GM; n = 8), all medal winners (MW; n = 13), non-medallists (NM; n = 12), and NM plus silver and …