Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Sports Sciences (750)
- Public Health (745)
- Nursing (639)
- Medical Specialties (489)
- Diseases (435)
-
- Medical Sciences (338)
- Social and Behavioral Sciences (276)
- Oncology (244)
- Neurosciences (193)
- Mental and Social Health (180)
- Rehabilitation and Therapy (180)
- Public Health Education and Promotion (167)
- Dietetics and Clinical Nutrition (158)
- Nursing Midwifery (127)
- Psychology (127)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (122)
- Life Sciences (121)
- Epidemiology (120)
- Psychiatry and Psychology (109)
- Occupational Health and Industrial Hygiene (85)
- Education (75)
- Physical Sciences and Mathematics (71)
- Maternal, Child Health and Neonatal Nursing (67)
- Endocrinology, Diabetes, and Metabolism (64)
- Communication Sciences and Disorders (54)
- Sociology (51)
- Chemicals and Drugs (49)
- Medical Genetics (49)
- Diagnosis (48)
- Keyword
-
- [RSTDPub] (405)
- Exercise (170)
- Human (135)
- Australia (126)
- Cancer (124)
-
- Article (108)
- Physical activity (107)
- Male (96)
- Alzheimer's disease (95)
- Female (95)
- Dementia (90)
- Mental health (87)
- Nursing (85)
- Western Australia (78)
- Children (77)
- Resistance training (76)
- Adult (74)
- Alzheimer’s disease (74)
- Quality of life (74)
- COVID-19 (70)
- Controlled study (69)
- Systematic review (68)
- Biomarkers (67)
- Diet (65)
- Health (65)
- Public health (65)
- Rehabilitation (65)
- Prostate cancer (64)
- Stroke (63)
- Cognition (62)
- Publication Year
- Publication
-
- Research outputs 2022 to 2026 (2302)
- Research outputs 2014 to 2021 (1525)
- Theses: Doctorates and Masters (465)
- Theses : Honours (227)
- Research outputs pre 2011 (102)
-
- Research outputs 2013 (101)
- Research outputs 2012 (90)
- Research outputs 2011 (40)
- Journal of the Australian Indigenous HealthInfoNet (38)
- ECU Posters (16)
- Australian Journal of Teacher Education (11)
- Research Datasets (11)
- Australian Indigenous HealthBulletin (10)
- Australian eHealth Informatics and Security Conference (10)
- ECU Research Week (10)
- 'INSCAPE' - ARTCAP November 13-16, 2003 (6)
- eCULTURE (5)
- Australian Information Security Management Conference (4)
- EDU-COM International Conference (2)
- Reports accepted as research outputs (1)
- School of Psychology and Social Science Presentations (1)
- Publication Type
- File Type
Articles 1291 - 1320 of 4977
Full-Text Articles in Medicine and Health Sciences
Dismantling Pervasive Gender Stereotypes In Healthcare Leadership Contexts With An Ecological Systems Theory Approach, Andrei A. Lux, Nasim Salehi, Diarmuid Hurley, Elizabeth Emanuel
Dismantling Pervasive Gender Stereotypes In Healthcare Leadership Contexts With An Ecological Systems Theory Approach, Andrei A. Lux, Nasim Salehi, Diarmuid Hurley, Elizabeth Emanuel
Research outputs 2022 to 2026
Leadership emergence is fraught with pervasive gender stereotypes, and women remain underrepresented in senior leadership roles, particularly in healthcare organisations. We apply ecological systems theory to explain how environmental factors enable or inhibit women’s leadership emergence in healthcare settings. We interviewed 17 senior female leaders in the Australian healthcare sector to explore how gender-related perceptions affected their leadership journeys. Five themes emerged that challenge existing narratives: men supported women’s advancement; women impeded other women’s progress; vulnerability was a leadership strength; ambitious women were ostracised; and women were ‘given’ leadership opportunities rather than actively pursuing them. By situating these findings within …
Resting Heart Rate Mediates The Association Between Circulating Neutrophil Count And Arterial Stiffness Progression: The Kailuan Study, Zhaogui Wu, Dan Wu, Shuohua Chen, Sichi Xu, Shunming Zhang, Shouling Wu
Resting Heart Rate Mediates The Association Between Circulating Neutrophil Count And Arterial Stiffness Progression: The Kailuan Study, Zhaogui Wu, Dan Wu, Shuohua Chen, Sichi Xu, Shunming Zhang, Shouling Wu
Research outputs 2022 to 2026
Objective: This study aimed to longitudinally investigate the association between circulating neutrophil count and the progression of arterial stiffness and to ascertain whether resting heart rate (RHR) mediates this association. Methods: The current study included 56,760 participants with brachial-ankle pulse wave velocity (baPWV) measurements from a real-life, prospective cohort in China. The associations of circulating neutrophil (exposure) with baseline baPWV, baPWV progression, and arterial stiffness (outcomes), as well as RHR (mediator) were assessed using multivariable linear and Cox regression models and mediation analysis. Results: After adjusting for cardiometabolic risk factors, for each 1-SD increase in neutrophil count, the corresponding increase …
Sleep Discrepancy And Brain Glucose Metabolism In Community-Dwelling Older Adults, Nadia Soh, Michael Weinborn, James D. Doecke, Rodrigo Canovas, Vincent Doré, Ying Xia, Jurgen Fripp, Kevin Taddei, Romola S. Bucks, Hamid R. Sohrabi, Ralph N. Martins, Melissa Ree, Stephanie R. Rainey-Smith
Sleep Discrepancy And Brain Glucose Metabolism In Community-Dwelling Older Adults, Nadia Soh, Michael Weinborn, James D. Doecke, Rodrigo Canovas, Vincent Doré, Ying Xia, Jurgen Fripp, Kevin Taddei, Romola S. Bucks, Hamid R. Sohrabi, Ralph N. Martins, Melissa Ree, Stephanie R. Rainey-Smith
Research outputs 2022 to 2026
Sleep discrepancy (negative discrepancy reflects worse self-reported sleep than objective measures, such as actigraphy, and positive discrepancy the opposite) has been linked to adverse health outcomes. This study is first to investigate the relationship between sleep discrepancy and brain glucose metabolism (assessed globally and regionally via positron emission tomography), and to evaluate the contribution of insomnia severity and depressive symptoms to any associations. Using data from cognitively unimpaired community-dwelling older adults (N = 68), cluster analysis was used to characterise sleep discrepancy (for total sleep time (TST), wake after sleep onset (WASO), and sleep efficiency (SE)), and logistic regression was …
Injury In Starting And Replacement Players From Five Professional Men’S Rugby Unions, Simon P. Roberts, Keith A. Stokes, Sean Williams, Stephen W. West, Simon Kemp, Matt Cross, Isabel S. Moore, Charlotte L. Bitchell, Prabhat Mathema, Ken Quarrie, Warren Mcdonald, Lauren Fortington, Eduardo R. Rubio Del Castillo, Clint Readhead, Nicola Sewry, Éanna Falvey, Ross Tucker
Injury In Starting And Replacement Players From Five Professional Men’S Rugby Unions, Simon P. Roberts, Keith A. Stokes, Sean Williams, Stephen W. West, Simon Kemp, Matt Cross, Isabel S. Moore, Charlotte L. Bitchell, Prabhat Mathema, Ken Quarrie, Warren Mcdonald, Lauren Fortington, Eduardo R. Rubio Del Castillo, Clint Readhead, Nicola Sewry, Éanna Falvey, Ross Tucker
Research outputs 2022 to 2026
Objectives: The aim of this study was to compare the incidence, severity, and burden of injury in starting and replacement players from professional men’s teams of five rugby unions. Methods: Match injuries of greater than 24 h time-loss (including data on the severity, match quarter, event, body region) and player minutes of match exposure data were collated for all starting and replacement players in the men’s English Premiership, Welsh Pro14 (both 2016/17–2018/19 seasons), and Australian, New Zealand, and South African Super Rugby (all 2016–2018 seasons) teams. Injury incidences and mean injury burden (incidence × days missed) were calculated, and rate …
Mitigating Intensive Care Unit Noise: Design-Led Modeling Solutions, Calculated Acoustic Outcomes, And Cost Implications, Emil E. Jonescu, Benjamin Farrel, Chamil E. Ramanayaka, Christopher White, Giuseppe Costanzo, Lori Delaney, Rebecca Hahn, Janet Ferrier, Edward Litton
Mitigating Intensive Care Unit Noise: Design-Led Modeling Solutions, Calculated Acoustic Outcomes, And Cost Implications, Emil E. Jonescu, Benjamin Farrel, Chamil E. Ramanayaka, Christopher White, Giuseppe Costanzo, Lori Delaney, Rebecca Hahn, Janet Ferrier, Edward Litton
Research outputs 2022 to 2026
Objectives, Purpose, or Aim: The study aimed to decrease noise levels in the ICU, anticipated to have adverse effects on both patients and staff, by implementing enhancements in acoustic design. Background: Recognizing ICU noise as a significant disruptor of sleep and a potential hindrance to patient recovery, this study was conducted at a 40-bed ICU in Fiona Stanley Hospital in Perth, Australia. Methods: A comprehensive mixed-methods approach was employed, encompassing surveys, site analysis, and acoustic measurements. Survey data highlighted the importance of patient sleep quality, emphasizing the negative impact of noise on work performance, patient connection, and job satisfaction. Room …
Nutrients And Polyphenols-Rich Sorghum Bicolor Genotypes As Complementary Therapy For Alzheimer’S Disease, Rasheed A. Abdulraheem, Ralph N. Martins, Prashant Bharadwaj, Zhaoyu Li, Ranil Coorey, Stuart Johnson, W. M. A. D. Binosha Fernando
Nutrients And Polyphenols-Rich Sorghum Bicolor Genotypes As Complementary Therapy For Alzheimer’S Disease, Rasheed A. Abdulraheem, Ralph N. Martins, Prashant Bharadwaj, Zhaoyu Li, Ranil Coorey, Stuart Johnson, W. M. A. D. Binosha Fernando
Research outputs 2022 to 2026
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and most common cause of dementia among older people. The main pathological hallmarks of AD are formation of insoluble amyloid beta senile plaques and paired helical filaments of neurofibrillary tangles. AD features gradual memory decline, mild to severe cognitive impairment, eventually total dependence of patients on caregivers. Currently available drugs have not been able to modify AD pathology. This has drawn increasing attention to plant food materials with high nutritional and bioactive constituents as potential complementary therapy for AD. Sorghum bicolor is a widely available cost-effective source of proteins, fats, crude fibres, …
The Impact Of Exercise On Blood-Based Biomarkers Of Alzheimer’S Disease In Cognitively Unimpaired Older Adults, Kelsey R. Sewell, Stephanie R. Rainey-Smith, Steve Pedrini, Jeremiah J. Peiffer, Hamid R. Sohrabi, Kevin Taddei, Shaun J. Markovic, Ralph N. Martins, Belinda M. Brown
The Impact Of Exercise On Blood-Based Biomarkers Of Alzheimer’S Disease In Cognitively Unimpaired Older Adults, Kelsey R. Sewell, Stephanie R. Rainey-Smith, Steve Pedrini, Jeremiah J. Peiffer, Hamid R. Sohrabi, Kevin Taddei, Shaun J. Markovic, Ralph N. Martins, Belinda M. Brown
Research outputs 2022 to 2026
Physical activity is a promising preventative strategy for Alzheimer’s disease: it is associated with lower dementia risk, better cognition, greater brain volume and lower brain beta-amyloid. Blood-based biomarkers have emerged as a low-cost, non-invasive strategy for detecting preclinical Alzheimer’s disease, however, there is limited literature examining the effect of exercise (a structured form of physical activity) on blood-based biomarkers. The current study investigated the influence of a 6-month exercise intervention on levels of plasma beta-amyloid (A 42, A 40, A 42/40), phosphorylated tau (p-tau181), glial fibrillary acidic protein (GFAP) and neurofilament light (NfL) chain in cognitively unimpaired older adults, and …
It Takes It Out Of The Textbook: Benefits Of And Barriers To Expert By Experience Involvement In Pre-Registration Mental Health Nursing Education, Brenda Happell, Sarah Gordon, John Hurley, Kim Foster, Mike Hazelton, Richard Lakeman, Lorna Moxham, Terri Warner
It Takes It Out Of The Textbook: Benefits Of And Barriers To Expert By Experience Involvement In Pre-Registration Mental Health Nursing Education, Brenda Happell, Sarah Gordon, John Hurley, Kim Foster, Mike Hazelton, Richard Lakeman, Lorna Moxham, Terri Warner
Research outputs 2022 to 2026
What Is Known on the Subject?: Service user involvement in mental health nursing education is beneficial in terms of attitudinal change to reduce stigma, clinical skill development and enhancing understandings of recovery-oriented practice. Service users as experts by experience have not been embedded within pre-registration nursing programs. Consequently, they remain limited in number, ad hoc and frequently tokenistic. Nurse academics responsible for the design and delivery of pre-registration mental health nursing curricula have a potentially important role in facilitating expert by experience involvement in mental health nursing education. What this Paper Adds to Existing Knowledge: Nurse academics teaching mental health …
Music As A Determinant Of Health Among First Nations People In Australia: A Scoping Narrative Review, Brigitta Scarfe, Kristy Apps, Naomi Sunderland, Phil Graham, Brydie Leigh Bartleet, Glenn Barry, Darren Garvey, Rae Cooper, Clint Bracknell
Music As A Determinant Of Health Among First Nations People In Australia: A Scoping Narrative Review, Brigitta Scarfe, Kristy Apps, Naomi Sunderland, Phil Graham, Brydie Leigh Bartleet, Glenn Barry, Darren Garvey, Rae Cooper, Clint Bracknell
Research outputs 2022 to 2026
Issue Addressed:
While social determinants frameworks are still popular in research about First Nations health in Australia, a growing body of research prefers cultural determinants of health models. Cultural determinants models provide a holistic, strength-based framework to explain connections between health and contextual factors, including the potential role of music and its impact on social and emotional well-being. Given the growing international recognition of links between music, health, and wellbeing through bodies such as the World Health Organisation, this article examines whether and how music practices are acknowledged in First Nations determinants of health literature.
Methods:
We conducted a scoping …
Rationale, Design, And Baseline Characteristics Of Participants In The Health@Nus Mhealth Augmented Cohort Study Examining Student-To-Work Life Transition: Protocol For A Prospective Cohort Study, Xin Hui Chua, Sarah Martine Edney, Andre Matthias Müller, Nicholas A. Petrunoff, Clare Whitton, Zoey Tay, Claire Marie Jie Lin Goh, Bozhi Chen, Su Hyun Park, Salome A. Rebello, Alicia Low, Janelle Chia, Daphne Koek, Karen Cheong, Rob M. Van Dam, Falk Müller-Riemenschneider
Rationale, Design, And Baseline Characteristics Of Participants In The Health@Nus Mhealth Augmented Cohort Study Examining Student-To-Work Life Transition: Protocol For A Prospective Cohort Study, Xin Hui Chua, Sarah Martine Edney, Andre Matthias Müller, Nicholas A. Petrunoff, Clare Whitton, Zoey Tay, Claire Marie Jie Lin Goh, Bozhi Chen, Su Hyun Park, Salome A. Rebello, Alicia Low, Janelle Chia, Daphne Koek, Karen Cheong, Rob M. Van Dam, Falk Müller-Riemenschneider
Research outputs 2022 to 2026
Background: Integration of mobile health data collection methods into cohort studies enables the collection of intensive longitudinal information, which gives deeper insights into individuals’ health and lifestyle behavioral patterns over time, as compared to traditional cohort methods with less frequent data collection. These findings can then fill the gaps that remain in understanding how various lifestyle behaviors interact as students graduate from university and seek employment (student-to-work life transition), where the inability to adapt quickly to a changing environment greatly affects the mental well-being of young adults. Objective: This paper aims to provide an overview of the study methodology and …
Role Of Short Chain Fatty Acids On Astrocytes And Microglia In Alzheimer's Disease Brain, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Matthew Burton, Welisarage Mary Kendrea Thiasangee Fernando, Vijay Jayasena, Charles Brennan, Wanakulasuriya Mary Ann Dipika Binosha Fernando
Role Of Short Chain Fatty Acids On Astrocytes And Microglia In Alzheimer's Disease Brain, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Matthew Burton, Welisarage Mary Kendrea Thiasangee Fernando, Vijay Jayasena, Charles Brennan, Wanakulasuriya Mary Ann Dipika Binosha Fernando
Research outputs 2022 to 2026
Short-chain fatty acids (SCFAs) hold exert many nutritional benefits on both physiological and pathological processes, including host metabolism, immune modulation, and appetite control. Originating from the microbial fermentation of resistant starches and dietary fibre in the colon, SCFAs have the capability to traverse the blood–brain barrier (BBB). It is evident that SCFAs play a critical role in the development of neurodegenerative disorders such as Alzheimer's disease (AD). AD is the most common form of dementia and is characterised by the deposition of amyloid β peptides (Aβ) and tau hyperphosphorylation. SCFAs have demonstrated the potential to interfere with the protein–protein interactions …
The Impact Of Mandated Use Early Warning System Tools On The Development Of Nurses' Higher-Order Thinking: A Systematic Review, Tracy Flenady, Justine Connor, Amy Louise Byrne, Deb Massey, Marie Danielle Le Lagadec
The Impact Of Mandated Use Early Warning System Tools On The Development Of Nurses' Higher-Order Thinking: A Systematic Review, Tracy Flenady, Justine Connor, Amy Louise Byrne, Deb Massey, Marie Danielle Le Lagadec
Research outputs 2022 to 2026
Aim: Ascertain the impact of mandated use of early warning systems (EWSs) on the development of registered nurses' higher-order thinking. Design: A systematic literature review was conducted, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and checklist (Page et al., 2021). Data Sources: CINAHL, Medline, Embase, PyscInfo. Review Methods: Eligible articles were quality appraised using the MMAT tool. Data extraction was conducted independently by four reviewers. Three investigators thematically analysed the data. Results: Our review found that EWSs can support or suppress the development of nurses' higher-order thinking. EWS supports the development of higher-order thinking in two …
Association Between The Presence Of Helicobacter Pylori And The Development Of De Novo Anemia In Adults Undergoing Sleeve Gastrectomy, Tammy S. Carrillo-Levin, Maria F. Jaramillo-Ocharan, Gustavo Salinas-Sedo, Carlos J. Toro-Huamanchumo
Association Between The Presence Of Helicobacter Pylori And The Development Of De Novo Anemia In Adults Undergoing Sleeve Gastrectomy, Tammy S. Carrillo-Levin, Maria F. Jaramillo-Ocharan, Gustavo Salinas-Sedo, Carlos J. Toro-Huamanchumo
Research outputs 2022 to 2026
Background: Sleeve gastrectomy has gained prominence in obesity treatment, yet it is not without complications, such as the development of anemia in the medium term. Given the high prevalence of Helicobacter pylori infection in Peru, it is imperative to explore its potential association with this postoperative complication. Objective: To evaluate the association between the presence of Helicobacter pylori and the development of anemia 12 months after sleeve gastrectomy. Methods: A retrospective cohort study was carried out based on an analysis of secondary data from a private clinic in Lima, Peru, which included two groups of people over 18 years of …
Examining The Effects Of Dynamic And Isometric Resistance Training On Knee Joint Kinetics During Unplanned Sidesteps In Elite Female Athletes, Daniel Kadlec, Matthew J. Jordan, Jacqueline Alderson, Sophia Nimphius
Examining The Effects Of Dynamic And Isometric Resistance Training On Knee Joint Kinetics During Unplanned Sidesteps In Elite Female Athletes, Daniel Kadlec, Matthew J. Jordan, Jacqueline Alderson, Sophia Nimphius
Research outputs 2022 to 2026
Kadlec, D, Jordan, MJ, Alderson, J, and Nimphius, S. Examining the effects of dynamic and isometric resistance training on knee joint kinetics during unplanned sidesteps in elite female athletes. J Strength Cond Res XX(X): 000-000, 2024 - The purpose of this study was to examine the effects of a 4-week block of isometric (isometricRT) and dynamic resistance training (dynamicRT) on kinetic variables associated with anterior cruciate ligament (ACL) injury risk during unplanned sidesteps in elite female athletes. Twenty-one elite female athletes competing for a women's international rugby union team were recruited with 15 (n = 15; age: 23.4 ± 4.7 …
Measuring Attitude Change In Nursing Students After Completion Of A First Nations Peoples’ Health Unit: Embedding A Validated Tool In Learning And Assessment Practices, Kylie Mccullough, Angela Genoni, Melanie Murray, Darren Garvey, Linda Coventry
Measuring Attitude Change In Nursing Students After Completion Of A First Nations Peoples’ Health Unit: Embedding A Validated Tool In Learning And Assessment Practices, Kylie Mccullough, Angela Genoni, Melanie Murray, Darren Garvey, Linda Coventry
Research outputs 2022 to 2026
The health inequities experienced by Aboriginal and Torres Strait Islander peoples, rooted in the historical and ongoing negative impacts of colonisation and disrupted traditional lifestyles, sees higher rates of illness and hospitalisations, increased morbidity and higher premature death rates than other Australians. Nurses represent the majority of Australia’s health workforce and nursing students must have knowledge to provide culturally safe care to Australia’s Aboriginal and Torres Strait Islander peoples. An Aboriginal and Torres Strait Islander Peoples’ Health and Wellbeing unit was developed and introduced into an undergraduate nursing curriculum. This project aimed to determine the effectiveness of the unit content …
Nurses’ Attitude Toward Trauma-Informed Care In Critical Care Units: A Cross-Sectional Study, Hashem Alkotaifan, Raghad H. Abdelkader, Mohammad N. Alshloul, Shaher H. Hamaeh, Mohammed S. Albashtawy, Nazzal M. Alshloul, Doha M. Alshloul
Nurses’ Attitude Toward Trauma-Informed Care In Critical Care Units: A Cross-Sectional Study, Hashem Alkotaifan, Raghad H. Abdelkader, Mohammad N. Alshloul, Shaher H. Hamaeh, Mohammed S. Albashtawy, Nazzal M. Alshloul, Doha M. Alshloul
Research outputs 2022 to 2026
Objective: Trauma-informed care (TIC) is an innovative concept that recognizes the lasting impact of psychological trauma. Critical care nurses’ attitude toward TIC plays an essential role in assessing, monitoring, and addressing trauma experienced by patients. This study aimed to describe critical care nurses’ attitudes toward TIC in critical care units at Jordanian military hospitals. Methods: This descriptive-analytical cross-sectional study was performed on 315 critical care nurses at seven military hospitals (two from the north, three from the center, and two from the south) in 2022. The data collection tool was the Attitudes Related to Trauma-Informed Care-35 (ARTIC-35) scale. Multi-stage sampling …
Re-Living Trauma Near Death: An Integrative Review Using Grounded Theory Narrative Analysis, Nikki Johnston, Michael Chapman, Jo Gibson, Catherine Paterson, Murray Turner, Karen Strickland, Wai Man Liu, Christine Phillips, Kasia Bail
Re-Living Trauma Near Death: An Integrative Review Using Grounded Theory Narrative Analysis, Nikki Johnston, Michael Chapman, Jo Gibson, Catherine Paterson, Murray Turner, Karen Strickland, Wai Man Liu, Christine Phillips, Kasia Bail
Research outputs 2022 to 2026
Background: Symptoms of emotional and physical stress near death may be related to previous experiences of trauma. Objective: To investigate current evidence regarding the following: (1) Is previous trauma identified in people who are dying, and if so, how? (2) How is previous trauma associated with the experience of death/dying in people with or without cognitive impairment? and (3) What palliative care interventions are available to people with previous trauma at the end of life? Design: This integrative review was conducted per Whittemore and Knafl’s guidelines, which involves a stepped approach, specifically (1) problem identification, (2) literature search, (3) data …
Variations In The Germinal Center Response Revealed By Genetically Diverse Mouse Strains, Anne Marie Aubin, Daria Vdovenko, Roxanne Collin, Lois Balmer, Lise Coderre, Grant Morahan, Félix Lombard-Vadnais, Sylvie Lesage
Variations In The Germinal Center Response Revealed By Genetically Diverse Mouse Strains, Anne Marie Aubin, Daria Vdovenko, Roxanne Collin, Lois Balmer, Lise Coderre, Grant Morahan, Félix Lombard-Vadnais, Sylvie Lesage
Research outputs 2022 to 2026
The humoral response is complex and involves multiple cellular populations and signaling pathways. Bacterial and viral infections, as well as immunization regimens, can trigger this type of response, promoting the formation of microanatomical cellular structures called germinal centers (GCs). GCs formed in secondary lymphoid organs support the differentiation of high-affinity plasma cells and memory B cells. There is growing evidence that the quality of the humoral response is influenced by genetic variants. Using 12 genetically divergent mouse strains, we assessed the impact of genetics on GC cellular traits. At steady state, in the spleen, lymph nodes and Peyer's patches, we …
Specific Vegetable Types Are Associated With Lower Long-Term Risk For Late-Life Dementia: The Perth Longitudinal Study Of Aging Women, Negar Ghasemifard, Simone Radavelli-Bagatini, Simon M. Laws, Helen Macpherson, Emma Stevenson, Jonathan M. Hodgson, Richard L. Prince, Joshua R. Lewis, Marc Sim
Specific Vegetable Types Are Associated With Lower Long-Term Risk For Late-Life Dementia: The Perth Longitudinal Study Of Aging Women, Negar Ghasemifard, Simone Radavelli-Bagatini, Simon M. Laws, Helen Macpherson, Emma Stevenson, Jonathan M. Hodgson, Richard L. Prince, Joshua R. Lewis, Marc Sim
Research outputs 2022 to 2026
This study examined the relationship between total vegetable intake, including specific vegetable types with long-term late-life dementia (LLD) risk in older Australian women. 1206 community-dwelling older women aged ≥70 years were included. Consumption of total vegetable intake and vegetable types (yellow/orange/red [YOR], cruciferous, allium, green leafy vegetables [GLV], and legumes) were estimated using a validated food frequency questionnaire at baseline (1998). LLD was considered any form of dementia occurring after 80 years of age. LLD events (comprising hospitalisation and/or death) were obtained from linked health records. Associations were examined using restricted cubic splines within multivariable-adjusted (including APOE4 genotype) Cox proportional …
A 16-Week Progressive Exercise Training Intervention In Treatment-Naïve Chronic Lymphocytic Leukaemia: A Randomised-Controlled Pilot Study, Frankie F. Brown, Rebecca Oliver, Rachel Eddy, Adam J. Causer, Annabelle Emery, Harrison D. Collier-Bain, David Dutton, Josephine Crowe, Daniel Augustine, John Graby, Daniel Rees, Daniela Rothschild-Rodriguez, Oliver J. Peacock, Sally Moore, James Murray, James E. Turner, John P. Campbell
A 16-Week Progressive Exercise Training Intervention In Treatment-Naïve Chronic Lymphocytic Leukaemia: A Randomised-Controlled Pilot Study, Frankie F. Brown, Rebecca Oliver, Rachel Eddy, Adam J. Causer, Annabelle Emery, Harrison D. Collier-Bain, David Dutton, Josephine Crowe, Daniel Augustine, John Graby, Daniel Rees, Daniela Rothschild-Rodriguez, Oliver J. Peacock, Sally Moore, James Murray, James E. Turner, John P. Campbell
Research outputs 2022 to 2026
Background: Chronic lymphocytic leukaemia (CLL) typically presents with asymptomatic, early-stage disease that is monitored until disease progression (‘treatment-naïve’ CLL). The objective of this pilot study was to assess the feasibility and preliminary safety of an exercise program in treatment-naïve CLL. We also sought to preliminarily assess the impact of the exercise program on disease activity, as it has been proposed that exercise training may reduce disease outgrowth in treatment-naïve CLL. Methods: A total of 40 treatment-naïve CLL patients were recruited into this randomised-controlled pilot study, and after screening, n = 28 were randomised into a 16-week, home-based, partially supervised, personalised, …
Exploratory Analysis Of Fight-Ending Punches In The Ultimate Fighting Championship™ Mixed Martial Arts Promotion, Oliver R. Barley, Colin S. Doherty, Mark Scanlan, Liam C. Tapsell, Corey Wilson, Julian Giustiniano, Matthew G. Plush, Shayne Vial
Exploratory Analysis Of Fight-Ending Punches In The Ultimate Fighting Championship™ Mixed Martial Arts Promotion, Oliver R. Barley, Colin S. Doherty, Mark Scanlan, Liam C. Tapsell, Corey Wilson, Julian Giustiniano, Matthew G. Plush, Shayne Vial
Research outputs 2022 to 2026
Punching is a crucial element of mixed martial arts (MMA), often leading to knockouts (KO) or technical knockouts (TKOs). This study explored the relative foot positions of athletes, their stances, punch type executed, and the reliability of these variables to provide insights into effective punch application in MMA. We retrospectively examined MMA contests from the Ultimate Fighting Championship that ended via KO/TKO (2020 to 2022). Data were sourced from publicly available videos on the internet. Three analysts, each with at least three years of experience in striking combat sports and competitive MMA, conducted observations independently. Only critical strikes where all …
The Implementation And Evaluation Of A Family-Led Novel Intervention For Delirium Prevention And Management In Adult Critically Ill Patients: A Mixed-Methods Pilot Study, Gideon U. Johnson, Amanda Towell-Barnard, Christopher Mclean, Beverley Ewens
The Implementation And Evaluation Of A Family-Led Novel Intervention For Delirium Prevention And Management In Adult Critically Ill Patients: A Mixed-Methods Pilot Study, Gideon U. Johnson, Amanda Towell-Barnard, Christopher Mclean, Beverley Ewens
Research outputs 2022 to 2026
Background: Family-led interventions have been identified as effective in many areas of care including the management of delirium. However, because of the heterogeneity and ambiguity of family-led interventions, they are not consistently applied within intensive care units. A user-friendly digital intervention may therefore support consistent family integration into delirium management. Aim: To explore the feasibility and acceptability of a family member's voice reorientation intervention for delirium prevention and management in an adult intensive care unit. Study Design: Parallel, convergent mixed-methods pilot study was conducted in a general adult intensive care unit in the United Kingdom. Thirty participants (15 patients and …
Characterization Of Pain In Lipedema: Reliability And Validity Of Pain Pressure Thresholds And Hand-Held Sphygmomanometer Assessments In People With Lipedema, Francesco Bettariga, Luca Fumagalli, Daniele Aloisi, Luca Maestroni, Sara Mantovani
Characterization Of Pain In Lipedema: Reliability And Validity Of Pain Pressure Thresholds And Hand-Held Sphygmomanometer Assessments In People With Lipedema, Francesco Bettariga, Luca Fumagalli, Daniele Aloisi, Luca Maestroni, Sara Mantovani
Research outputs 2022 to 2026
Background: Lipedema is a chronic condition characterized by abnormal deposition of subcutaneous adipose tissue, leading to pain. The lack of internationally recognized diagnostic criteria complicates the characterization of pain. Physiological parameters such as pain pressure threshold (PPT) represent promising prognostic markers for diagnosing lipedema, yet they remain understudied. This study aimed to evaluate the reliability and validity of two pain pressure measurements, PPT and the hand-held sphygmomanometer (HHS) in lipedema. Methods: A total of 28 adult females diagnosed with lipedema were recruited. Both PPT, using a digital algometer, and HHS, using a manual aneroid HHS, were performed to assess pain …
Summary Of Epidemiology, Prevention And Management Of Blood-Borne Viruses Experienced By Aboriginal And Torres Strait Islander Peoples, Australian Indigenous Healthinfonet
Summary Of Epidemiology, Prevention And Management Of Blood-Borne Viruses Experienced By Aboriginal And Torres Strait Islander Peoples, Australian Indigenous Healthinfonet
Research outputs 2022 to 2026
This Summary is based on the Review of epidemiology, prevention and management of blood-borne viruses experienced by Aboriginal and Torres Strait Islander peoples (2024).
It aims to provide a synthesis of key information on blood-borne viruses (BBVs) experienced by Aboriginal and Torres Strait Islander peoples in Australia, focusing primarily on hepatitis B virus, hepatitis C virus, and human immunodeficiency virus.
It covers: the historical, social and cultural context of Aboriginal and Torres Strait Islander peoples and BBVs the extent of BBVs, including incidence, prevalence, health service utilisation, hospitalisation, mortality, and burden of disease prevention and management of BBVs relevant programs, …
Great Southern Food Community: Snapshot Report, Isabelle Chiera, Jess Doe, Amanda Devine, Melissa Stoneham, Stephanie L. Godrich
Great Southern Food Community: Snapshot Report, Isabelle Chiera, Jess Doe, Amanda Devine, Melissa Stoneham, Stephanie L. Godrich
Research outputs 2022 to 2026
Food security refers to the adequate physical, social, and economic access to healthy food at all times. The Great Southern Food Community project aimed to identify, map, evaluate and strengthen food security initiatives across the region, to support food security action. This report outlines the findings from the Great Southern Food Community project, detailing the different types of food security initiatives operating within the region. It provides a summary of how Great Southern initiatives are contributing to food security systems change, and how they are working in partnership to deliver their food security initiatives. Based on these findings, region-based recommendations …
Kimberley Food Community: Snapshot Report, Isabelle Chiera, Jess Doe, Amanda Devine, Melissa Stoneham, Stephanie L. Godrich
Kimberley Food Community: Snapshot Report, Isabelle Chiera, Jess Doe, Amanda Devine, Melissa Stoneham, Stephanie L. Godrich
Research outputs 2022 to 2026
Food security refers to the adequate physical, social, and economic access to healthy food at all times. The Kimberley Food Community project aimed to identify, map, evaluate and strengthen food security initiatives across the region, to support food security action. This report outlines the findings from the Kimberley Food Community project, detailing the different types of food security initiatives operating within the region. It provides a summary of how Kimberley initiatives are contributing to food security systems change, and how they are working in partnership to deliver their food security initiatives. Based on these findings, region-based recommendations are provided to …
Effects Of Resveratrol Supplementation On Delayed Onset Muscle Soreness And Muscle Recovery: A Systematic Review, Nurdiana Zainol Abidin, Cheong Hwa Ooi, Kazunori Nosaka, Vishanth Rathakrishnan, Siok Yee Chan, Noor Khairiah A. Karim
Effects Of Resveratrol Supplementation On Delayed Onset Muscle Soreness And Muscle Recovery: A Systematic Review, Nurdiana Zainol Abidin, Cheong Hwa Ooi, Kazunori Nosaka, Vishanth Rathakrishnan, Siok Yee Chan, Noor Khairiah A. Karim
Research outputs 2022 to 2026
Delayed onset muscle soreness (DOMS) and impaired muscle recovery significantly affect athletes and recreational exercisers, influencing their performance and training consistency. Resveratrol, a natural polyphenol known for its anti-inflammatory and antioxidant properties, is thought to mitigate these effects, yet its effectiveness remains to be fully verified. This systematic review evaluates the impact of RES supplementation on muscle recovery in adults by examining its influence on DOMS, oxidative stress, and inflammation, along with its interactions with other supplements. Three electronic databases and one registry were searched in October 2023. A total of 10 studies met the inclusion criteria, encompassing a combined …
Factors Affecting Clinician Readiness To Adopt Smart Home Technology For Remote Health Monitoring: Systematic Review, Gordana Dermody, Daniel Wadsworth, Melissa Dunham, Courtney Glass, Roschelle Fritz
Factors Affecting Clinician Readiness To Adopt Smart Home Technology For Remote Health Monitoring: Systematic Review, Gordana Dermody, Daniel Wadsworth, Melissa Dunham, Courtney Glass, Roschelle Fritz
Research outputs 2022 to 2026
Background: The population of older adults worldwide continues to increase, placing higher demands on primary health care and long-term care. The costs of housing older people in care facilities have economic and societal impacts that are unsustainable without innovative solutions. Many older people wish to remain independent in their homes and age in place. Assistive technology such as health-assistive smart homes with clinician monitoring could be a widely adopted alternative to aged-care facilities in the future. While studies have found that older persons have demonstrated a readiness to adopt health-assistive smart homes, little is known about clinician readiness to adopt …
Parental Assessment Of Postsurgical Pain In Infants At Home Using Artificial Intelligence–Enabled And Observer-Based Tools: Construct Validity And Clinical Utility Evaluation Study, Fatos Sada, Paola Chivers, Sokol Cecelia, Sejdi Statovci, Kujtim Ukperaj, Jeffery Hughes, Kreshnik Hoti
Parental Assessment Of Postsurgical Pain In Infants At Home Using Artificial Intelligence–Enabled And Observer-Based Tools: Construct Validity And Clinical Utility Evaluation Study, Fatos Sada, Paola Chivers, Sokol Cecelia, Sejdi Statovci, Kujtim Ukperaj, Jeffery Hughes, Kreshnik Hoti
Research outputs 2022 to 2026
Background: Pain assessment in the infant population is challenging owing to their inability to verbalize and hence self-report pain. Currently, there is a paucity of data on how parents identify and manage this pain at home using standardized pain assessment tools. Objective: This study aimed to explore parents’ assessment and intervention of pain in their infants at home following same-day surgery, using standardized pain assessment tools. Methods: This prospective study initially recruited 109 infant boys undergoing circumcision (same-day surgery). To assess pain at home over 3 days after surgery, parents using iOS devices were assigned to use the PainChek Infant …
Study Protocol For A Nested Process Evaluation Of A Complex Discharge Planning Intervention (Home Rehab) To Improve Participation After First-Stroke, Sandra Reeder, Mandy Stanley, Laura J. Jolliffe, Natasha A. Lannin
Study Protocol For A Nested Process Evaluation Of A Complex Discharge Planning Intervention (Home Rehab) To Improve Participation After First-Stroke, Sandra Reeder, Mandy Stanley, Laura J. Jolliffe, Natasha A. Lannin
Research outputs 2022 to 2026
Introduction: Stroke is a leading cause of adult disability, and the transition from hospital to home can be fraught with challenges. The HOME Rehab trial is designed to address if better health outcomes for stroke survivors can be achieved with a contextually relevant and tailored occupational therapy discharge planning and support intervention. Process evaluations inform clinical trial findings and future scale up, as well as how to implement a successful intervention effectively into policy and practice. This paper describes the protocol we are using in the HOME Rehab process evaluation planning and activities.
Methods: Using a theoretically informed approach, mixed …