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Relationship Of Serum Leptin And 25-Hydroxyvitamin D In Knee Osteoarthritis Patients, Pacharee Manoy, Wilai Anomasiri, Pongsak Yuktanandana, Aree Tanavalee, Thomas Mabey, Sittisak Honsawek
Relationship Of Serum Leptin And 25-Hydroxyvitamin D In Knee Osteoarthritis Patients, Pacharee Manoy, Wilai Anomasiri, Pongsak Yuktanandana, Aree Tanavalee, Thomas Mabey, Sittisak Honsawek
Chulalongkorn Medical Journal
Background : Osteoarthritis (OA) is a degenerative articular disease that involves progressive alterations in all joint structures resulting from aging and overuse activity. Leptin and vitamin D play a crucial role in energy metabolism; however, few reports on leptin and 25-hydroxyvitamin D (25(OH)D) in knees of osteoarthritis (OA) has been known.Objectives : To examine serum levels of leptin and vitamin D in knee OA patients and analyze the possible relationship between serum leptin, 25-hydroxyvitamin D, and clinical parameters in OA patients.Methods : In a cross-sectional study, 235 adult patients (212 women and 23 men, aged 65.6 6.5 years) with …