Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Relationship Of Serum Leptin And 25-Hydroxyvitamin D In Knee Osteoarthritis Patients, Pacharee Manoy, Wilai Anomasiri, Pongsak Yuktanandana, Aree Tanavalee, Thomas Mabey, Sittisak Honsawek
Relationship Of Serum Leptin And 25-Hydroxyvitamin D In Knee Osteoarthritis Patients, Pacharee Manoy, Wilai Anomasiri, Pongsak Yuktanandana, Aree Tanavalee, Thomas Mabey, Sittisak Honsawek
Chulalongkorn Medical Journal
Background : Osteoarthritis (OA) is a degenerative articular disease that involves progressive alterations in all joint structures resulting from aging and overuse activity. Leptin and vitamin D play a crucial role in energy metabolism; however, few reports on leptin and 25-hydroxyvitamin D (25(OH)D) in knees of osteoarthritis (OA) has been known.Objectives : To examine serum levels of leptin and vitamin D in knee OA patients and analyze the possible relationship between serum leptin, 25-hydroxyvitamin D, and clinical parameters in OA patients.Methods : In a cross-sectional study, 235 adult patients (212 women and 23 men, aged 65.6 6.5 years) with …
Single Nucleotide Polymorphism (Snp) Of Leptin Gene In Holstein Cattle, Mohammed Baqur S. Al-Shuhaib, Sara M. A. Al-Lamy, Hafedh M. A. Al-Tayy, Tahreer M. Al-Thuwaini, Adil H. Radhi
Single Nucleotide Polymorphism (Snp) Of Leptin Gene In Holstein Cattle, Mohammed Baqur S. Al-Shuhaib, Sara M. A. Al-Lamy, Hafedh M. A. Al-Tayy, Tahreer M. Al-Thuwaini, Adil H. Radhi
The Thai Journal of Veterinary Medicine
Leptin is a versatile important hormone that regulates several metabolic pathways, such as controlling body weight, feed intake, energy expenditure, immune function, and reproduction. This study was conducted to describe the single nucleotide polymorphisms (SNPs) within bovine leptin (LEP) gene, and their possible consequences on leptin structure and function in Holstein cattle. After collecting blood samples from 60 Holstein cattle, extracting their genomic DNA, two PCR-specific primers were designed. Both PCR and SSCP experiments were optimized and performed for each PCR fragment. Each different set of SSCP resolved bands was sequenced and analyzed. Two SSCP patterns representing two genotypes (AA, …