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Research News. Publications, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period October 1 through December 31, 2019

Patient Safety Smartphone Application For Quality Assurance In Primary Healthcare Facilities, Levina Chandra Khoe, Ajeng Pramastuty, Boy Subirosa Sabarguna, Herquranto Herqutanto

ASEAN Journal of Community Engagement

In order to achieve high-quality healthcare, patient safety should be improved and monitored regularly. Moreover, accreditation on healthcare facilities is being requested in recent years. Mobile application can serve as a tool for community healthcare centre’s (Puskesmas) to assess their accreditation score, especially patient safety. To provide as a tool for self-monitoring for patient safety elements. This is a case-based article focuses on the development of smartphone application using the input-process-output-outcome scheme as the framework. We reviewed regulation of health minister on Puskesmas accreditation and developed a checklist and scoring for patient safety components. This is the first mobile application …

Voice Disorders In Teachers, Hsin-Yu Chien, Feng-Chuan Lin, Yu-Lin Huang

Rehabilitation Practice and Science

Teachers have higher occupational voice demands than the general populations. In addition to speaking intensively in a noisy environment for a long period of time, the lack of vocal hygiene education and vocal training experience will lead to high-risk for developing voice disorders. Although voice disorders are not life-threatening diseases, it affects teachers in many aspects. In addition to impacting teachers' personal physical and psychological condition, it also interferes with the quality of students' learning, which then bring down teachers' teaching and life quality, and even more so on teachers' mental health and career path. In order to help teachers …

A Focal Survey Of Medical Professionals' Conceptions Of Gastrostomy In Patients With Dysphagia After Stroke In Taiwan, Sheng-Hao Cheng, Yi-Ching Chen, Ming-Yen Hsiao, Tyng-Guey Wang

Rehabilitation Practice and Science

Background and aims: People with dysphagia may require long-term tube feeding to maintain adequate nutrition. In Taiwan, nasogastric (NG) tubes are more commonly used than gastrostomy tubes. This practice is inconsistent with international treatment guidelines. Medical professionals' attitudes toward treatment may influence patients' decisions. Therefore, we designed a questionnaire to assess whether medical professionals' conceptions of gastrostomy are consistent with current international treatment principles. Methods: We used an online questionnaire hosted on ＂Google Forms＂ to collect medical professionals' conceptions of gastrostomy. Societies related to dysphagia distributed copies of the questionnaire to their members. The professionals included specialists (physiatrists, otolaryngologists, oral …

Bedside Thyroid Palpation Technique As Indicator For Penetration/Aspiration Risk In Stroke Patients, Yung-Chun Chi, Mu-Hung Tsai, Jerry Tsung-Kai Lin, Yi-Chen Yu, Shih-Chung Chang

Rehabilitation Practice and Science

Background: Bedside thyroid cartilage palpation technique is a quick and non-invasive swallowing screening test. However, the correlation between thyroid cartilage movement and penetration/aspiration risks in stroke patients has not been conclusive to date. Therefore, we compared the result of videofluoroscopic swallowing study (VFSS) and bedside thyroid cartilage palpation to determine the penetration/ aspiration risks in stroke patients. Material and methods: Our study included 53 patients admitted to a medical center for rehabilitation within 6-months of stroke onset. We recorded penetration-aspiration scale by VFSS and compared it with a bedside thyroid cartilage palpation technique. Results: Our results show significant higher rates …

Cytomegalovirus Infection Complicated With Severe Rhabdomyolysis And Dysphagia: A Casereport And Literature Reviewarticle, Heng-An Yeh, Yu-Jen Chen, Jean-Lon Chen

Rehabilitation Practice and Science

Cytomegalovirus(CMV) is a common virus that usually occurs in immunocompromised patients. After primary infection with CMV, the virus becomes latent in multiple organs and can later be reactivated during severe immune system dysregulation. Rhabdomyolysis is a disease of human muscle cell necrosis, and the rapid dissolution of damaged or injured muscles may lead to acute kidney injury or multiple organ failure. After reviewarticleing relevant literature, patients with severe rhabdomyolysis caused by CMV infection are rarely reported and even less commonly, CMV leads to severe dysphagia. The patient was a 35-year-old woman without underlying disease. Two months before hospitalization,she visited the …

Research News. Grants, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during October-December 2019

Connectivity Differences Between Gulf War Illness (Gwi) Phenotypes During A Test Of Attention, Tomas Clarke, Jessie Jamieson, Patrick Malone, Rakib U. Rayhan, Stuart Washington, John W. Vanmeter, James N. Baraniuk

Department of Mathematics: Faculty Publications

One quarter of veterans returning from the 1990–1991 Persian Gulf War have developed Gulf War Illness (GWI) with chronic pain, fatigue, cognitive and gastrointestinal dysfunction. Exertion leads to characteristic, delayed onset exacerbations that are not relieved by sleep. We have modeled exertional exhaustion by comparing magnetic resonance images from before and after submaximal exercise. One third of the 27 GWI participants had brain stem atrophy and developed postural tachycardia after exercise (START: Stress Test Activated Reversible Tachycardia). The remainder activated basal ganglia and anterior insulae during a cognitive task (STOPP: Stress Test Originated Phantom Perception). Here, the role of attention …

Association Between Obesity And History Of Atopy With Atopic Dermatitis In Children: A Cross-Sectional Study, Putu Nila Wardhani Batan, Ariana Ariana, Made Wardhana

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: The prevalence of atopic dermatitis (AD) has rapidly increased in the past 4 decades and has been mostly observed in children. The prevalence of obesity has also significantly increased worldwide, suggesting that the two conditions may be associated.

Methods: This retrospective analytic study involved a cross-sectional design and used secondary data taken from the medical record of patients who visited the Pediatric Dermatology Subdivision at Dermatology and Venereology Polyclinic Sanglah General Hospital from January 2015 to December 2015. Thirty-two samples were selected.

Results: The prevalence ratio of obesity among subjects with AD was 2.178 (95% CI …

The Epidemiology Of Skin Cancer At Dr. Cipto Mangunkusumo National Central General Hospital From 2014 To 2017, Larisa Paramitha Wibawa, Melody Febriana Andardewi, Inge Adi Kristanti, Riesye Arisanty

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: The incidence of skin cancer has been increasing over the past decades globally. At present, there is no valid national cancer data in Indonesia. The purpose of this study is to evaluate the increment of skin cancer cases at Dr. Cipto Mangunkusumo National General Hospital, Jakarta.

Methods: In this retrospective descriptive study, we evaluated all pigmented skin tumor cases from June 2014 to June 2017. Data were obtained from the Department of Anatomical Pathology and medical records at Dr. Cipto Mangunkusumo National General Hospital. Data were compared with previous reports.

Results: From 263 skin cancer cases, …

Effectiveness Of Balloon Angioplasty And Stent Angioplasty: Wound Healing In Critically Limb Ischemic, Wisnu Pamungkas, Patrianef Darwis

The New Ropanasuri Journal of Surgery

Introduction. Critical limb ischemia (CLI) is a vascular disease that has a significant amputation and mortality risk with diabetes mellitus; the most significant risk factor in CLI is prevalent among Indonesian. Endovascular intervention (EVI) is preferred in treating CLI because it is non-invasive and effective. Balloon angioplasty and stent angioplasty are the most common method of EVI in Indonesia. This study aims to compare the effectiveness of balloon angioplasty and stent angioplasty on wound healing in CLI.

Method. A cross sectional study enrolled 90 subjects of CLI who underwent endovascular intervention using balloon angioplasty dan stent angioplasty from …

Correlation Between Internal Jugular Vein Tunnel Cuffed Catheter Tip Position As Hemodialysis Access With Suspected Catheter Related Bacteremia And Related Risk Factors At Rscm 2018–2019, Susatyo J. Pratomo, Akhmadu Muradi

The New Ropanasuri Journal of Surgery

Introduction. Infection is the main complication of prolonged–term catheter uses as hemodialysis access. The KDOQI recommends the insertion of tunnel venous hemodialysis catheter in the right internal jugular vein (IJV) where the tip placed in the right atrium and the arterial opening enfacing the mediastinum. The previous study showed that the incidence of catheter–related bacteremia (CRB) is 35% at three months' use and 54% at six months' use. The TCC tip position as hemodialysis access in left IJV is correlated more to dysfunction and infection compared to the right IJV.

Method. A cross–sectional study was conducted with 62 subjects …

Characteristics Of Habitat, Distribution, And Diversity Of Anopheles Spp In Kemelak Bindung Langit Village, Ogan Komering Ulu Regency, South Sumatra, Giri Maretasari, Yuanita Windusari, Syafrina Lamin, Laila Hanum, Dwi Septiawati

Journal of Environmental Science and Sustainable Development

Malaria is an infectious disease caused by Plasmodium andis transmitted through the bite of a female Anopheles vector. Ogan Komering Ulu (OKU) is a district in South Sumatra that is endemic to malaria. The study aims to determine habitat type, environmental factors that influence larvae development, and distribution of Anopheles larvae. The experiment was conducted from January to February 2019 in the Kelurahan Kemelak Bindung Langit, OKU. Species identification was carried out in the Entomology Laboratory, Baturaja Health Research and Development Center, OKU. Sampling locations were determined based on field observations, through simple purposive sampling. Identification of mosquito larvae which …

Pengaruh Pemberian Jus Mentimun Dan Minuman Isotonik Terhadap Tingkat Dehidrasi Pada Latihan Zumba Fitness, Rizki Yudha Pratama, Imas Damayanti, Yati Ruhayati

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian jus mentimun dan minuman isotonik terhadap tingkat dehidrasi. Metode yang digunakan yaitu dengan eksperimen dengan desain penelitian cross over design. 8 orang mahasiswa keperawatan UPI 2018 berpartisipasi sebagai sampel dalam penelitian ini. Dehydrating exercise test yang digunakan dalam penelitian ini adalah Zumba fitness selama 60 menit. Instrumen pengambilan data menggunakan Urine Refractometer Spesific Gravity dan 5 visual analog scale. Hasil dari penelitian ini menunjukkan bahwa tidak terdapat perbedaan yang signifikan antara hasil pre-test dan post-test pada jus mentimun dan minuman isotonik terhadap tingkat dehidrasi sebesar p(0.83) dan p(1.52). Pada penilaian subjektif tidak terdapat …

Hubungan Komposisi Tubuh Dengan Kesegaran Jasmani Pada Atlet Hockey, Nandita Nury Latifah, Ani Margawati, Ayu Rahadiyanti

Jurnal Keolahragaan

Komposisi tubuh yang tidak optimal dapat menurunkan kesegaran jasmani atlet sehingga dapat terjadi penurunan performa ketika bertanding. Tujuan dari penelitian ini adalah mengetahui hubungan persen lemak tubuh, persen massa otot, dan somatotype dengan kesegaran jasmani pada atlet hockey. Desain penelitian yaitu cross-sectional dengan jumlah subjek 35 atlet di Pelatihan Hockey Universitas Negeri Semarang dan Universitas Negeri Yogyakarta yang dipilih dengan purposive sampling. Data persen lemak tubuh dan persen massa otot diukur menggunakan bioelectrical impedence analysis (BIA). Data somatotype menggunakan metode antropometri Heath-Carter dan data kesegaran jasmani berupa nilai VO2max diambil menggunakan metode Balke. Analisis data menggunakan uji Pearson, …

Efektivitas Small-Sided Games Dan Interval Training Terhadap Peningkatan Daya Tahan Aerobik Pada Pemain Sepakbola U-17, Andi Tri Arianto, Caly Setyawan

Jurnal Keolahragaan

Penelitian ini bertujuan untuk membandingkan pengaruh antara latihan small sided games (SSG) dan interval training (IT) terhadap daya tahan aerobik pemain sepakbola under-17. Sebanyak 24 pemain sepakbola U-17 yang dibagi menjadi 2 grup: grup SSG (n = 12) dan grup IT (n = 12) mengikuti program latihan selama 6 minggu. Instrumen penelitian yang digunakan adalah Yo-Yo Intermitten Recovery Test. ANAVA dua jalur digunakan untuk proses analisis data. Pemain dari kedua grup menunjukkan peningkatan yang sama pada daya tahan aerobik selama periodesasi latihan 6 minggu. Hasil ini menunjukkan bahwa SSG dan IT sama efektif dalam meningkatkan daya tahan aerobik …

Social And Psychological Factors Associated With Health Care Transition For Young Adults Living With Sickle Cell Disease, Dora L. Clayton-Jones, Nadine Matthie, Marsha Treadwell, Joshua Field, Amy Mager, Rachel Sawdy, Safiya George Dalmida, Cynthia Leonard, Kathryn L. Koch, Kristin Haglund

College of Nursing Faculty Research and Publications

Introduction: Due to advances in disease management, mortality rates in children with sickle cell disease (SCD) have decreased. However, mortality rates for young adults (YA) increased, and understanding of social and psychological factors is critical. The aim of this study was to explore factors associated with health care transition experiences for YA with SCD.

Method: This was a qualitative descriptive study. A 45-minute semistructured interview was conducted with 13 YA (M = 21.5 years, SD = 1.73).

Results: Results suggest that social and psychological factors and self-management experiences influence health care transition. Eight themes emerged: “need for accessible support”; “early …

Efektivitas Massage Frirage Dan Kombinasi Back Massage-Stretching Untuk Penyembuhan Nyeri Pinggang, Ardi Utomo, B.M. Wara Kushartanti

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengungkapkan: (1) pengaruh jenis perlakuan massage frirage dan kombinasi back massage-stretching untuk penyembuhan nyeri pinggang, (2) pengaruh kondisi cedera akut dan kronis terhadap penyembuhan nyeri pinggang, dan (3) interaksi jenis perlakuan dengan kondisi cedera terhadap penyembuhan nyeri pinggang yang ditunjukkan peningkatan ROM pinggang pada pasien Physical Therapy Clinic Fakultas Ilmu Keolahragaan Universitas Negeri Yogyakarta (PTC FIK UNY). Penelitian ini adalah eksperimen dengan desain faktorial 2 x 2, dengan menggunakan tes awal dan tes akhir. Subjek penelitian ini adalah 40 orang pasien klinik PTC yang mengalami nyeri pinggang kronis maupun akut akibat aktivitas kerja yang berjenis kelamin …

Assessment Practices Followed By Speech-Language Pathologists For Clients With Suspected Speech Sound Disorder In Taiwan: A Survey Study, Yen-Ning Chang, Li-Li Yeh

Rehabilitation Practice and Science

Speech sound disorder (SSD) is one of the most frequently occurring types of human communication disorders. Approximately one-fourth of the clients of speech-language therapy clinics are diagnosed with SSD by speech-language pathologists (SLPs). Thus, investigating the professional development of SSD assessment by SLPs across various working contexts in Taiwan is important. The present study used a specifically designed questionnaire on SSD assessment. A sample size of 150 SLPs, who comprised 18% of all SLPs in Taiwan (the northern, middle, southern, and eastern regions), were invited to fill in the questionnaire anonymously. The questionnaire contained the following topics: time spent for …

Identification And Evaluation Of Antibacterial Compounds From The Vibrio Sp. Associated With The Ascidian Pycnoclavella Diminuta, Abdurraafi’ Maududi Dermawan, Elin Julianti, Masteria Yunovilsa Putra

Pharmaceutical Sciences and Research

This study aims to obtain secondary metabolites that have antibacterial activity from bacteria endophytic of ascidian Pycnoclavella diminuta collected from the coast of Bitung, North Sulawesi, Indonesia. The research was started with screening antibacterial activity of six bacteria isolated from P. diminuta. The active bacteria were selected for identification using standard biological molecular method and further fermentation to produce secondary metabolites. The isolation of secondary metabolites was conducted by various chromatography method and then selected fraction was based on the antibacterial activity from bioautography results. The result showed that the active isolate by coding M2.Tnk.Bt 5.10-3.2 was identified as Vibrio …

Chemical Components Of Ocimum Basilicum L. And Ocimum Tenuiflorum L. Stem Essential Oils And Evaluation Of Their Antioxidant Activities Using Dpph Method, Ni Putu Ermi Hikmawanti, Hariyanti, Nurkamalia, Sahera Nurhidayah

Pharmaceutical Sciences and Research

Ocimum basilicum L. and Ocimum tenuiflorum L. are two types of plants from Ocimum (Lamiaceae). One of their chemical compounds is essential oil. Essential oil might have an antioxidant activities. The part of the plants which are often wasted and never used are stem. This study aimed to analyze the chemical components of O. basilicum L. and O. tenuiflorum L. stem essential oils and evaluate their antioxidant activities. Essential oils were obtained by steam-water distillation. Analysis of chemical component of essential oil was performed using Gas Chromatography-Mass Spectroscopy (GC-MS). Antioxidant activities were evaluated with DPPH method and then the IC50 …

Cytotoxic Activity Of Stem Of Pycnarrhena Cauliflora Through Apoptosis Induction On Human Breast Cancer Cell Line T47d, Masriani, Rudiyansyah, Rini Muharini, Eny Enawaty

Pharmaceutical Sciences and Research

Cytotoxic activities of extracts of Pycnarrhena cauliflora leaves, stems and roots on some human cancer cells have been known. However, the cytotoxicity of stem of Pycnarrhena cauliflora on human breast cancer cell line T47D through an apoptosis induction has not been proven yet. This study was an effort in understanding the cytotoxic activity of stem of Pycnarrhena cauliflora through apoptosis induction. The crude ethanol extract was partitioned between n-hexane and dichloromethane at pH 3, 7 and 9, which was subsequently tested for their cytotoxic activity against human breast cancer cell line T47D by using 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT). Flow cytometric …

Is Vertical Orientation Ability And Visual Feedback Training Strategy Useful For Pusher Syndrome After Stroke: A System Reviewarticle, Chien-Hsun Lee

Rehabilitation Practice and Science

Stroke patients with pusher syndrome (PS) have a longer recovery time than those without this disorder. This special syndrome causes difficulty in maintaining balance when sitting or standing, with sufferers ＂pushing and leaning＂ automatically to hemi-side. PS patients may also have cognition impairment, hemi-neglect, or aphasia. Alleviating all these factors requires extensive training for therapists, however, few undergo such training. Wang et. al. published a reviewarticle article in Taiwan Journal of Physical Medicine and Rehabilitation in 2005, and the conclusions drawn were: 1) PS patients have abnormal subjective posture and vertical orientation ability; 2) training strategies that use visual feedback …

Effectiveness Of Post-Acute Rehabilitation On Functional Outcome After Hip Fracture, Yen-Ju Wang, Pei-Hsin Lin, Li-Ning Peng, Mu-Jung Kao, Serena Y.C Lin, Kuan-Hua Huang, Yen-Fang Chen, Miao-Ru Liang

Rehabilitation Practice and Science

Objective: We investigated the effectiveness of functional recovery after 2-week post-acute rehabilitation in elderly people with hip fractures. Design: We divided the patients (N = 129) into 2 groups: the post-acute care (PAC) group (N = 90) that received 2-week in-hospital rehabilitation and the control group (N =39) that were discharged immediately. Outcomes were measured according to the Barthel Index (BI) score. Results: The BI scores at 2 weeks, 3 months, and 6 months were higher in the PAC group than those in the control group, especially for transfer and mobility. Males, aged less than 80 years old, or who …

Bpc 157 Promotes Skeletal Muscle Cells Migration In Association With Up-Regulation Of Paxillin And Vinculin Expression, Szu-Heng Wang, Li-Ping Lin, Miao-Sui Lin, Jong-Hwei S. Pang, Wen-Chung Tsai

Rehabilitation Practice and Science

BPC 157 was first isolated from human gastric juice. It is a stable 15-amino acid fragment (GEPPPGKPADDAGLV), and the healing-promoting effects of BPC 157 have been reported on muscle injury. The aim of this study was to investigate the effect and molecular mechanism of BPC 157 on migration of skeletal muscle cells. Skeletal muscle cells were isolated from the gastrocnemius muscle of Sprague-Dawley rats, and treated with BPC 157. The cell migration was evaluated by transwell filter migration assay. The spreading of cells was evaluated microscopically. The protein expressions of paxillin and vinculin (which were positive regulators of cell migration) …

Serial Electromyographic Evaluations In Patients With Unilateral Vocal Fold Paralysis, Yu-Wei Hu, Tuan-Jen Fang, Ying-Hsun Chen, Szu-Heng Wang, Wei-Sen Chen, Shao-Chih Hsu, Yu-Cheng Pei

Rehabilitation Practice and Science

Background: Unilateral vocal fold paralysis causes incomplete closure of the glottis. Clinical manifestations include hoarseness and dysphagia, thus hindering the patients' quality of life. To characterize chronological laryngeal electromyographic changes, this prospective study evaluated laryngeal electromyography and voice at two time points in patients with unilateral vocal fold paralysis. Study design: A retrospective study. Methods: In this study, 12 patients with unilateral vocal fold paralysis who did not receive surgical treatment or injection therapy were recruited. Laryngeal electromyography was performed on the thyroarytenoid-lateral cricoarytenoid (TA-LCA) muscle complex and cricothyroid (CT) muscle, and quantitative analysis was conducted on the TA-LCA muscle …

Risk Factors For Concussion And Head, Neck, And Facial Injuries In Amateur Mixed Martial Arts Athletes, Hsin-Chin Lin, Carl P. C. Chen, Tung-Yang Yu, Yu-Ann Wang, Szu Heng Wang, Yu-Min Chien

Rehabilitation Practice and Science

The popularity of mixed martial arts (MMA) has been on the rise globally since the year 2000 and Taiwan is no exception. Because MMA is a contact sport, it can cause sport-related injuries, especially concussion and head, neck, and facial injuries. This is the first study to analyse the risk of concussion and other head, facial, and neck injuries in amateur MMA competitions in Taiwan. Forty-eight competitors were enrolled in this study. The epidemiology of injuries was recorded and analysed using logistic regressions and odds ratios in STATA 14; data analysed included locations and incidence of concussion and head, neck, …

Factors Influencing The Use Of Inpatient Rehabilitation Services Among Amputees In Acute Hospitals: An Observational Study, Ya-Ling Huang, Ming-Chung Yang, Chun-Chieh Wu, Tung-Chou Li

Rehabilitation Practice and Science

Objective: To examine rates of inpatient rehabilitation (IR) use in a nationwide amputee and determine factors associated with receiving rehabilitation services during acute admission. Methods: This research is a retrospective observational study. We sampled data from a nationally representative sample of 1,000,000 enrollees of the single-payer government-based National Health Insurance (NHI) program in Taiwan from 1996 to 2013. Claims data for rehabilitation during index admission after amputation were analyzed, and factors associated with IR use were identified. Multivariable logistic regression was performed with adjustment for clustering to identify which factors were independently associated with acute IR referral. Results: Among the …

Shoulder And Upper Extremities Function In Patients With Head And Neck Cancer After Selective Neck Dissection, Han-Chin Hsieh, Chau-Peng Leong, Yan-Yuh Lee, Chih-Yen Chien, Chia-Hsuan Lin, Yu-Chi Huang

Rehabilitation Practice and Science

Background: Shoulder dysfunction is common after nerve-sparing selective neck dissection (SND). We aimed to assess the upper extremity function and shoulder pain in patients with head and neck cancer (HNC) after SND. Methods: In this cross-sectional study, we enrolled 38 patients with HNCs after SND and evaluated shoulder active range of motion (ROM), muscle strength, pain, and the Disabilities of the Arm, Shoulder and Hand Score (DASH) questionnaire for upper extremity function on operative and non-operative sides. Results: Significant reductions in shoulder motions, muscle strength, and higher level of shoulder pain were observed on the operative side after SND. Worse …

Model Hewan Coba Pada Penelitian Diabetes, Fauzul Husna, Franciscus D. Suyatna, Wawaimuli Arozal, Erni H. Purwaningsih

Pharmaceutical Sciences and Research

The animal model has been widely used and contributed vastly to the scientific research over the years. While it can be used as an alternate subject in a study, the selection of the animal is crucial to assess and investigate the influence of the environment and genes on the pathogenesis of a disease. Many factors contribute to the choosing of the animal. They can be ranged from the similarities with the modelled object, easily looked after with less expensive cost, good reproductive performance, ability to produce blood and tissue samples, well-known genetic composition, and the status of the disease can …