Medicine and Health Sciences | Open Access Articles

Post-Resuscitation Care Practices Following Cardiac Arrest At Six Regional Interventional Cardiology Centers In The United States 2007-2011, David B. Seder Md, Nainesh Patel Md, John A. Mcpherson Md, Paul W. Mcmullan Md, Karl B. Kern Md, Barbara T. Unger Rn, J Browning, Sudip Nanda Md, Facp, Melkon Hacobian Md, Michael B. Kelley Md, Niklas Nielsen Md, Phd, Michael R. Mooney Md

Department of Medicine

No abstract provided.

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Call-Fleming Syndrome: More Than A Crazy Migraine, Erin M. Conahan Rn, Cnrn, Claranne Mathiesen Rn, Msn, Cnrn

Department of Medicine

No abstract provided.

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Cement Pulmonary Embolism: A Common And Potentially Serious Complication Of Vertebroplasty, Brigid Hallinan Do, Yehia Y. Mishriki Md

Department of Medicine

No abstract provided.

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Clinical Practice Guidelines For Rehab And Oncology, Stephanie L. Marshall Pt, Dpt, Ocs, Kathleen A. Leies Rn, Jennifer Roeder Mspt, Mba

Department of Medicine

No abstract provided.

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Comparative Prognostic Significance Of Sentinel Lymph Node Biopsy And Axillary Lymphadenectomy In Carcinoma Of The Breast, Aaron D. Bleznak Md, Facs, Jennifer Bleznak, Barbara Gutch Rn, Aileen Galley Msw

Department of Medicine

No abstract provided.

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En Coup De Sabre, Marie S. Lewars Do, Gwyn Frambach Do, Charles Grooper Md

Department of Medicine

No abstract provided.

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Esta En Sus Manos! It’S In Your Hands!, Lenore Mcgonigle Med, Vanessa Soto, Hannabi Torres, Heiwon Chung Md, Facs, Nadesda Mack Rn, Bsn, Mba, Ocn, Renae Stonehouse Rt, (R), (M), Maryellen Shiels Bs

Department of Medicine

No abstract provided.

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Improving The Quality Of Information Sent To Primary Care Physicians For Patients Discharged From Nursing Facilities, Catherine M. Glew Bm, Bs, Cmd, Anne M. Yawman Md

Department of Medicine

No abstract provided.

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Pseudo-Cushing’S Syndrome In A Hiv Patient With Complete Resolution Following Discontinuation Of Darunavir/Ritonavir, Rashmi Sharma Md, Margaret Hoffman-Terry Md, Facp

Department of Medicine

No abstract provided.

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Pyroglutamic Acidosis: A Rare And Underdiagnosed Cause Of High Anion Gap Metabolic Acidosis, Brigid Hallinan Do, Tina M. Casey Do, Matthew Mccambridge Md

Department of Medicine

No abstract provided.

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Reducing Readmissions To Hospital From A Skilled Nursing Facility, Catherine M. Glew Bm, Bs, Cmd, Anne M. Yawman Md

Department of Medicine

No abstract provided.

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Immunohistochemical Evaluation Of The Effects Of Nebivolol On Intimal Hyperplasia Following Endothelial Injury, İlker Akar, Ali̇ Rahman, M. Cengi̇z Çolak, Bi̇lal Üstündağ, İbrahi̇m Hani̇fi̇ Özercan, Ayhan Uysal

Turkish Journal of Medical Sciences

Intimal hyperplasia is a vascular remodeling process. It is a clinical problem that forms in the vascular wall as a result of smooth muscle cell migration, proliferation, and extracellular matrix accumulation. In this study we examined the immunohistochemical evaluation of the effects of nebivolol on intimal hyperplasia in damaged endothelial tissue. Materials and methods: The study was conducted using 21 rabbits equally divided into 3 groups: control, solvent, and nebivolol. The rabbits in the control group only underwent balloon injury of the abdominal aorta. The rabbits in the solvent group and nebivolol group underwent balloon injury and were treated with …

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Obesity In Children And Adolescents And Its Relationship With Hypertension, Dr Vijayanath Itagi, Ramesh Patil

Turkish Journal of Medical Sciences

It is difficult to project the prevalence of obesity and overweight among children in India since there is no nationally representative data from India. We determined the time trends in childhood obesity in a representative sample of schoolchildren from Raichur District, Karnataka and investigated the relationship of obesity with blood pressure. Materials and methods: We used a stratified random cluster sampling method to select the children. Anthropometric data were collected from 23,842 students, 5-16 years of age, during 2005-06. Blood pressure and anthropometric data were collected from 19,263 students during 2007-08. Overweight and obesity were defined by body mass index …

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The Effect Of Spiritualism On The Neuropsychological Function Of Memory, Carla Farcello

McNair Poster Presentations

The amount of physiological-neurological research performed over the past few years has dramatically increased due to our ability to view the structure and function of the brain in living human beings. The use of imaging tools has resulted in huge strides forward in unlocking some of the mysteries of the 3 pound universe-the human brain. One of the more unique neural processes being recently addressed is the affect of belief and spiritualism-the sense of being connected to something larger than oneself-on the human brain. This study hypothesized that better memory will be documented among the experimental group who report being …

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Children's Emotional State And False Memory In The Drm Paradigm, Pamela Cornejo

McNair Poster Presentations

Children are called to give testimony for highly emotional during court cases. Research indicates that children in a negative emotional state recall with lesser vividness (Berliner et al. 2003) and are more likely to incorporate false information (Levine, Burgess & Laney, 2008). The present study will examine this further by examining the influence of negative and positive emotional states on recall and recognition in child-normed lists within the Deese-Roediger-McDermott (DRM) paradigm. The DRM paradigm is a cognitive task that relies on gist memory for remembrance of the critical lure in semantically associated word lists. It is expected that the eight …

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An Efficient Method For Stable Transfection Of Mouse Myogenic C2c12 Cell Line Using A Nonviral Transfection Approach, Mehmet Deni̇z Akyüz, Burcu Hayta, Pervi̇n Ruki̇ye Di̇nçer

Turkish Journal of Medical Sciences

To describe in detail the use of the T-REx^{TM} System (a tetracycline-regulated mammalian expression system; Invitrogen) for rapid, easy, and effective generation of stable C2C12 cell clones. Tetracycline-inducible stable cell lines are useful tools to study the function of various genes in different types of mammalian cells. However, the generation of stable cell lines is a time-consuming, technically difficult, and expensive process. Materials and methods: Generation of a stable C2C12 cell line was performed by stable transfection of the cells with the pcDNA6/TR plasmid vector, which contains the tetracycline repressor and the blasticidin drug resistance genes. The establishment of the …

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The Role Of Anemia And Vitamin D Levels In Acute And Chronic Telogen Effluvium, Ayşe Serap Karadağ, Derun Taner Ertuğrul, Emre Tutal, Kadi̇r Okhan Akin

Turkish Journal of Medical Sciences

Telogen effluvium (TE) is an abnormality of hair cycling. Vitamin D promotes hair follicle differentiation. The importance of vitamin D in hair growth is evident in patients with hereditary vitamin D receptor deficiency. The role of vitamin D in the pathogenesis of TE has not been investigated before. We investigated the role of vitamin D, ferritin, and zinc in the pathogenesis of TE. Materials and methods: We measured serum hemoglobin, ferritin, zinc, calcium, phosphate, parathormone, magnesium, 25 and 1,25-hydroxyvitamin D3, and bone alkaline phosphatase and thyroid stimulating hormone levels in 63 female patients and 50 control subjects. Twenty-nine of the …

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Distribution Of Congenital Heart Disease In Turkey*, Serdar Kula, Ayhan Çevi̇k, Fatma Rana Olguntürk, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Mustafa Necmi̇ İlhan

Turkish Journal of Medical Sciences

To describe the epidemiology and geographical distribution of congenital heart disease. A retrospective population-based study was conducted using data collected in a large tertiary care hospital in Turkey. Materials and methods: The medical records of 1300 patients with congenital heart disease admitted to the Gazi University Department of Pediatric Cardiology for catheter angiography from 1997-2007 were reviewed. The patients were divided into 7 groups according to geographical distribution, and each group was further divided into 2 groups, for simple (group 1) and complex (group 2) congenital heart disease. Results: Among the 1300 cases, there was no difference between the regions …

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Assessment Of The Left Atrial Longitudinal Myocardial Function By Assessment Of The Left Atrial Longitudinal Myocardial Function By The Strain And Strain Rate Echocardiography In Patients With Rheumatic Mitral Stenosis*, Enbi̇ya Aksakal, Serdar Sevi̇mli̇, Hanefi̇ Yekta Gürlertop, Mehmet Ali̇ Elbey, Muhammed Hakan Taş, Fuat Gündoğdu, Mustafa Kemal Erol, Şule Karakelleoğlu

Turkish Journal of Medical Sciences

To evaluate the regional left atrial (LA) myocardial functions and time to peak deformations by the longitudinal strain (S) and strain rate (Sr) echocardiography in isolated mitral stenosis (MS) patients for 3 LA periods (contractile, reservoir, and conduit periods). Materials and methods: Included in the study were 30 MS patients and 30 healthy controls. Longitudinal peak S and Sr indices, time to peak S and time to peak Sr, and systolic and diastolic velocities were measured from the color Doppler myocardial imaging data, for each LA period. Results: For all 3 periods, all of the segment S values and most …

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Gabaergic Signaling To Adult-Generated Neurons In Hippocampus, Sean Markwardt

All ETDs from UAB

In the central nervous system of adult mammals, new neurons are produced throughout life in at least two regions, the subventricular zone and dentate gyrus of the hippocampus. New neurons in the SVZ migrate via the rostral migratory stream and eventually participate in adaptive olfactory processes. In the dentate gyrus, a variety of physiological functions for continued addition of neurons have been proposed, but its role in normal or pathological conditions remains largely unclear. Neurogenesis in the dentate gyrus consists of the stepwise process of generating fully functional granule cells (GCs) from adult neural stem cells. Regulation of neurogenesis can …

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Role Of Calcium-Activated Potassium Channels In Glioblastoma Volume Regulation, Michael Bryan Mcferrin

All ETDs from UAB

The most common and most malignant gliomas are the Grade IV Glioblastoma Multiforme (GBM), characterized by a highly proliferative tumor mass and extremely invasive phenotype that allows for profuse dispersal of tumor cells throughout the brain. GBM cells must specifically regulate their cell volume to thrive within the edematous tumor mass and infiltrate throughout the tortuous extracellular spaces of the brain. These rapid and directed volume changes are governed by the controlled flux of potassium and chloride ions across the cell membrane, which move osmotically obliged water. The goal of this dissertation was to investigate the role of calcium-activated potassium …

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Killer Immunoglobulin-Like Receptors And Human Leukocyte Polymorphisms In Hiv-1 Pathogenesis, Aimee Marie Merino

All ETDs from UAB

Human leukocyte antigen (HLA) molecules influence the adaptive and innate immune responses through interactions with cytotoxic T lymphocytes and natural killer cells (NK). HLA influence the activation state of NK through direct binding to killer immunoglobulin-like receptors (KIR) and presentation of HLA-derived peptides to NKG2 receptors. Activated NK can kill HIV-infected cells through direct cytolysis and release cytokines that influence other aspects of the immune system. Variations in KIR gene content and allelic variants have been associated with autoimmunity, transplantation success, and infectious diseases such as hepatitis C and HIV/AIDS. We investigated the impact of KIR genes and potential KIR-HLA …

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Structural And Mechanistic Studies On Er Upr Sensor Perk And Mitochondrial Translocon Element Tim44, Wenjun Cui

All ETDs from UAB

The unfolded protein response is one mechanism utilized by endoplasmic reticulum (ER) to maintain the homeostasis between ER protein folding machinery and ER proteins. UPR is induced by three ER transmembrane sensors: IRE1, ATF6 and PERK. PKR-like ER kinase (PERK) can sense the ER stress signal through its luminal domain to activate its cytoplasmic kinase domain catalytic activity. PERK kinase domain belongs to the eIF2α family. Members in this family are activated after being autophosphorylated at their activation loops and then specifically phosphorylate eIF2α at its Ser51 position. Phosphorylation of eIF2α can shutdown the cytosol protein translation from the initiation …

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Effects Of Estrogen On Hippocampal Function In Young Adult And Aged Female Rats, Lindsey Celeste Vedder

All ETDs from UAB

In rodents, the ovarian estrogen 17b-estradiol (E2) is a potent modulator of hippocampal function and the hippocampus is critical for many types of learning and memory. Specifically, E2 increase the magnitude of long-term potentiation (LTP) at CA3-CA1 synapses, the density of dendritic spines in CA1 pyramidal cells and current mediated by NR2B-containing NMDA receptors. The E2-induced increase in LTP further requires NR2B-containing NMDARs. While considered a cellular correlate of learning and memory, enhanced LTP does not always predict enhanced learning. The first goal of this dissertation was to investigate the relationship between E2-enhanced LTP and learning and memory in young …

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Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram

All ETDs from UAB

Successful treatment of breast cancer directly correlates with tumor stage and grade at diagnosis. Early diagnosis leads to a five-year relative survival rate of 96.8% as opposed to only a 22.5% five-year survival rate when diagnosed at late stage. Cancer-specific mechanisms need to be extended to enable cancer detection in an individual patient, in particular, the metastatic burden that currently cannot be assessed by conventional imaging. This approach for cancer detection would remove the biases of patient characteristics, permit immediate diagnostic feedback, improve sensitivity for early detection of small metastatic lesions, and be cost effective. Toward this goal, the cancer-specific …

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Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White

All ETDs from UAB

The virus Eastern Equine Encephalitis virus (EEEV) is a highly pathogenic arthropod-borne virus (arbovirus) present in the US. The virus is listed as a reportable illness to the Centers of Disease Control and Prevention (CDC) and is also listed as a select agent by Human Health and Services (HHS). Studies on EEEV starting back in the 1930's have determined many important facets of the ecology, transmission and evolution of the virus. It is understood that in many endemic foci, the mosquito Culiseta melanura is the primary enzootic vector of the virus. EEEV is thus maintained in an enzootic cycle between …

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Functional Interplay Between Trans Factors And Cis-Elements That Govern Il17a&F Transcription, Sarah Kern Whitley

All ETDs from UAB

Protective immunity against a variety of infections depends on the amplification and differentiation of naïve antigen-specific CD4 T cells. T helper 17 (Th17) cells are important for defending mucosal barriers from invading extracellular bacterial pathogens. This effector CD4 lineage is characterized by production of the cytokines IL-17A, IL-17F, IL-21, and IL-22, which elicit influx of inflammatory cells to promote pathogen clearance. The cytokines IL-6 and TGF&beta are the principal factors that initiate Th17 lineage development, and the STAT3-inducing cytokines IL-21 and IL-23 assist and/or maintain the Th17 developmental program. Recently, an additional cytokine has been demonstrated to encourage Th17 differentiation: …

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Regulation Of Neuronal Death By The Autophagy Lysosomal Pathway: Implications For Parkinson Disease, Violetta N. Pivtoraiko

All ETDs from UAB

Parkinson Disease (PD) is the second most common age-related neurodegenerative disorder and is characterized pathologically by the loss of dopaminergic (DA) neurons in the stubstantia nigra pars compacta (SNpc). Mitochondrial dysfunction, increased oxidative stress, and accumulation of aggregated α-synuclein (α-syn), an intracellular protein involved in synaptic function, are all pathological hallmarks of PD have been implicated in PD pathogenesis. However, it is debated whether α-syn aggregates themselves are responsible for neurodegeneration in PD, cellular pathways involved in degradation of α-syn aggregates are believed to promote neuron survival. The autophagy lysosomal pathway (ALP), a physiological mechanism for recycling of intracellular components, …

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Myosin Ii In Hippocampal Synapses: Regulation Of Synaptic Plasticity, Strength And Actin Dynamics By Two Distinct Isoforms, Maria Dolores Rubio

All ETDs from UAB

Cytoskeletal actin filaments underlie dendritic spine plasticity, critical for several forms of learning and memory. Therefore, understanding the mechanisms that regulate actin dynamics is essential to elucidate memory formation pathways. Myosins, a superfamily of actin binding proteins, have emerged as candidates for regulation of actin dynamics in the brain. Several myosin class II isoforms have been identified in brain, but their individual contribution to synaptic activity is still unknown. Based on the finding that myosin IIB regulates actin polymerization in the growth cone of developing neurons and that it is necessary for maintenance of dendritic spine structure, I hypothesized that …

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The Natural History Of Sivcpz Infection In Wild Living Chimpanzees, Rebecca Steele Rudicell

All ETDs from UAB

Simian immunodeficiency virus of chimpanzees (SIVcpz) is the immediate precursor to human immunodeficiency virus type 1 (HIV-1), but even the most basic aspects of SIVcpz infection in its natural host are unknown. Here, we present the first comprehensive analysis of the natural history of SIVcpz infection in wild living chimpanzees. Using non-invasive (feces and urine based) methods, we studied two unique chimpanzee populations in Tanzania: the famous chimpanzees of Gombe National Park and the savanna chimpanzees of Ugalla, located about 135 km southeast of Gombe. Gombe chimpanzees are endemically infected with SIVcpz, and the park's established research infrastructure provides a …

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Full-Text Articles in Medicine and Health Sciences

Department of Medicine

Call-Fleming Syndrome: More Than A Crazy Migraine, Erin M. Conahan Rn, Cnrn, Claranne Mathiesen Rn, Msn, Cnrn

Department of Medicine

Cement Pulmonary Embolism: A Common And Potentially Serious Complication Of Vertebroplasty, Brigid Hallinan Do, Yehia Y. Mishriki Md

Department of Medicine

Clinical Practice Guidelines For Rehab And Oncology, Stephanie L. Marshall Pt, Dpt, Ocs, Kathleen A. Leies Rn, Jennifer Roeder Mspt, Mba

Department of Medicine

Comparative Prognostic Significance Of Sentinel Lymph Node Biopsy And Axillary Lymphadenectomy In Carcinoma Of The Breast, Aaron D. Bleznak Md, Facs, Jennifer Bleznak, Barbara Gutch Rn, Aileen Galley Msw

Department of Medicine

En Coup De Sabre, Marie S. Lewars Do, Gwyn Frambach Do, Charles Grooper Md

Department of Medicine

Esta En Sus Manos! It’S In Your Hands!, Lenore Mcgonigle Med, Vanessa Soto, Hannabi Torres, Heiwon Chung Md, Facs, Nadesda Mack Rn, Bsn, Mba, Ocn, Renae Stonehouse Rt, (R), (M), Maryellen Shiels Bs

Department of Medicine

Improving The Quality Of Information Sent To Primary Care Physicians For Patients Discharged From Nursing Facilities, Catherine M. Glew Bm, Bs, Cmd, Anne M. Yawman Md

Department of Medicine

Pseudo-Cushing’S Syndrome In A Hiv Patient With Complete Resolution Following Discontinuation Of Darunavir/Ritonavir, Rashmi Sharma Md, Margaret Hoffman-Terry Md, Facp

Department of Medicine

Pyroglutamic Acidosis: A Rare And Underdiagnosed Cause Of High Anion Gap Metabolic Acidosis, Brigid Hallinan Do, Tina M. Casey Do, Matthew Mccambridge Md

Department of Medicine

Reducing Readmissions To Hospital From A Skilled Nursing Facility, Catherine M. Glew Bm, Bs, Cmd, Anne M. Yawman Md

Department of Medicine

Immunohistochemical Evaluation Of The Effects Of Nebivolol On Intimal Hyperplasia Following Endothelial Injury, İlker Akar, Ali̇ Rahman, M. Cengi̇z Çolak, Bi̇lal Üstündağ, İbrahi̇m Hani̇fi̇ Özercan, Ayhan Uysal

Turkish Journal of Medical Sciences

Obesity In Children And Adolescents And Its Relationship With Hypertension, Dr Vijayanath Itagi, Ramesh Patil

Turkish Journal of Medical Sciences

The Effect Of Spiritualism On The Neuropsychological Function Of Memory, Carla Farcello

McNair Poster Presentations

Children's Emotional State And False Memory In The Drm Paradigm, Pamela Cornejo

McNair Poster Presentations

An Efficient Method For Stable Transfection Of Mouse Myogenic C2c12 Cell Line Using A Nonviral Transfection Approach, Mehmet Deni̇z Akyüz, Burcu Hayta, Pervi̇n Ruki̇ye Di̇nçer

Turkish Journal of Medical Sciences

The Role Of Anemia And Vitamin D Levels In Acute And Chronic Telogen Effluvium, Ayşe Serap Karadağ, Derun Taner Ertuğrul, Emre Tutal, Kadi̇r Okhan Akin

Turkish Journal of Medical Sciences

Distribution Of Congenital Heart Disease In Turkey*, Serdar Kula, Ayhan Çevi̇k, Fatma Rana Olguntürk, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Mustafa Necmi̇ İlhan

Turkish Journal of Medical Sciences

Turkish Journal of Medical Sciences

Gabaergic Signaling To Adult-Generated Neurons In Hippocampus, Sean Markwardt

All ETDs from UAB

Role Of Calcium-Activated Potassium Channels In Glioblastoma Volume Regulation, Michael Bryan Mcferrin

All ETDs from UAB

Killer Immunoglobulin-Like Receptors And Human Leukocyte Polymorphisms In Hiv-1 Pathogenesis, Aimee Marie Merino

All ETDs from UAB

Structural And Mechanistic Studies On Er Upr Sensor Perk And Mitochondrial Translocon Element Tim44, Wenjun Cui

All ETDs from UAB

Effects Of Estrogen On Hippocampal Function In Young Adult And Aged Female Rats, Lindsey Celeste Vedder

All ETDs from UAB

Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram

All ETDs from UAB

Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White

All ETDs from UAB

Functional Interplay Between Trans Factors And Cis-Elements That Govern Il17a&F Transcription, Sarah Kern Whitley

All ETDs from UAB

Regulation Of Neuronal Death By The Autophagy Lysosomal Pathway: Implications For Parkinson Disease, Violetta N. Pivtoraiko

All ETDs from UAB

Myosin Ii In Hippocampal Synapses: Regulation Of Synaptic Plasticity, Strength And Actin Dynamics By Two Distinct Isoforms, Maria Dolores Rubio

All ETDs from UAB

The Natural History Of Sivcpz Infection In Wild Living Chimpanzees, Rebecca Steele Rudicell

All ETDs from UAB