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Articles 37591 - 37620 of 45334
Full-Text Articles in Medicine and Health Sciences
Association Analyses Of Oxidative Stress, Aerobic Capacity, Daily Physical Activity, And Body Composition Parameters In Patients With Mild To Moderate Copd, Abdurrahman Genç, Kağan Üçok, Ümi̇t Şener, Tülay Koyuncu, Olcay Akar, Sefa Çeli̇k, Mehmet Ünlü
Association Analyses Of Oxidative Stress, Aerobic Capacity, Daily Physical Activity, And Body Composition Parameters In Patients With Mild To Moderate Copd, Abdurrahman Genç, Kağan Üçok, Ümi̇t Şener, Tülay Koyuncu, Olcay Akar, Sefa Çeli̇k, Mehmet Ünlü
Turkish Journal of Medical Sciences
To investigate total oxidant and antioxidant status, maximal aerobic capacity, daily physical activity, pulmonary functions, and body composition changes, as well as the associations among these parameters, in patients with mild to moderate chronic obstructive pulmonary disease (COPD) versus healthy controls. Materials and methods: The study included 30 male patients newly diagnosed with COPD and 30 body mass index-matched, nonsmoker male controls. Maximal aerobic capacity, daily physical activity, total oxidant and antioxidant status, pulmonary function tests, body composition, and anthropometric parameters were measured. Results: Maximal aerobic capacity and total antioxidant values were lower in patients with COPD compared to the …
Effects Of Oral Hormone Replacement Therapy On Mean Platelet Volume In Postmenopausal Women, İkbal Kaygusuz, Serap Aynur Si̇mavli, Ayla Eser, İlknur İnegöl Gümüş, Selcen Yüksel, Zehra Candan İltemi̇r Duvan, Hasan Kafali
Effects Of Oral Hormone Replacement Therapy On Mean Platelet Volume In Postmenopausal Women, İkbal Kaygusuz, Serap Aynur Si̇mavli, Ayla Eser, İlknur İnegöl Gümüş, Selcen Yüksel, Zehra Candan İltemi̇r Duvan, Hasan Kafali
Turkish Journal of Medical Sciences
To examine the effects of hormone replacement therapy (HRT) on mean platelet volume (MPV), lipid profile, and C-reactive protein (CRP) levels in postmenopausal women who have a high risk and incidence of cardiovascular disease. Materials and methods: This study was performed retrospectively. Twenty-seven healthy postmenopausal women received 1 mg estradiol and 2 mg drospirenone orally for 6 months. Twenty-eight healthy postmenopausal women not taking any HRT were admitted to the study as the control population. Results: Time effect (independent from group effect) was statistically significant for the MPV variable (P = 0.025), but there was no significant change in MPV …
Endobronchial Ultrasound-Guided Transbronchial Needle Biopsy For The Diagnosis Of Mediastinal Lymphadenopathy In Patients With Extrathoracic Malignancies, Ayşegül Şentürk, Hati̇ce Kiliç, Habi̇be Hezer, Funda Karaduman Yalçin, Hati̇ce Canan Hasanoğlu
Endobronchial Ultrasound-Guided Transbronchial Needle Biopsy For The Diagnosis Of Mediastinal Lymphadenopathy In Patients With Extrathoracic Malignancies, Ayşegül Şentürk, Hati̇ce Kiliç, Habi̇be Hezer, Funda Karaduman Yalçin, Hati̇ce Canan Hasanoğlu
Turkish Journal of Medical Sciences
Mediastinal lymphadenopathy is common in extrathoracic malignancies and should not always be considered a metastatic lesion. The purpose of this study is to determine the diagnostic value of endobronchial ultrasound-guided transbronchial needle biopsy (EBUS-TBNA) in patients with extrathoracic malignancies. Materials and methods: This study included 54 consecutive patients with extrathoracic malignancies who had suspected mediastinal metastases and had undergone EBUS-TBNA for diagnosis. Results: Using EBUS-TBNA, 27 of 54 patients (50%) were diagnosed with mediastinal metastases. Among patients with mediastinal metastases, 2 (3.7%) had a sarcoid-like reaction, 5 (9.3%) had tuberculosis, and 17 (31.5%) had reactive lymph nodes. In 3 cases …
Effect Of Nodule Size On The Reliability Of Fine-Needle Aspiration Biopsy In Thyroid Nodules, Ali̇ Erkan Uçar, Seyyi̇t Muhsi̇n Sarikaya, Ömer Parlak, Abdussamed Yalçin
Effect Of Nodule Size On The Reliability Of Fine-Needle Aspiration Biopsy In Thyroid Nodules, Ali̇ Erkan Uçar, Seyyi̇t Muhsi̇n Sarikaya, Ömer Parlak, Abdussamed Yalçin
Turkish Journal of Medical Sciences
To investigate the reliability of fine-needle aspiration biopsy (FNAB) in thyroid nodules and benign/malignant discrimination, particularly in large nodules. Materials and methods: A retrospective analysis of 1466 nodules in 402 patients with thyroid nodules who underwent thyroid surgery was made. The pathologic results of the thyroid nodules from preoperative FNAB and postoperative surgical pathology results were compared. Results: FNAB was found to be in accordance with the postoperative pathologic results. A concordance between the FNAB and postoperative pathologic results, particularly in nodules less than 3 cm in size, was detected. However, a similar finding was not detected in nodules larger …
The Role Of Fdg-Pet/Ct In Detecting Unsuspected And Unknown Distant Metastasis In The Initial Staging Of Nsclc, Meti̇n Halaç, Meftune Özhan, Sabi̇re Yilmaz Aksoy, Betül Vatankulu, Anar Aliyev, Sertaç Asa, Ersan Atahan, Muhammet Sai̇t Sağer, Keri̇m Sönmezoğlu
The Role Of Fdg-Pet/Ct In Detecting Unsuspected And Unknown Distant Metastasis In The Initial Staging Of Nsclc, Meti̇n Halaç, Meftune Özhan, Sabi̇re Yilmaz Aksoy, Betül Vatankulu, Anar Aliyev, Sertaç Asa, Ersan Atahan, Muhammet Sai̇t Sağer, Keri̇m Sönmezoğlu
Turkish Journal of Medical Sciences
Our purpose in this retrospective study was to determine the ratio of unexpected [metastases within the coverage area of thorax computed tomography (CT)] and unknown (metastases out of the coverage area of thorax CT) metastases by positron emission tomography/CT (PET/CT) in patients with newly diagnosed non-small cell lung cancer (NSCLC) who had no defined metastatic lesion, and to investigate the contribution of fludeoxyglucose (FDG)-PET/CT in metastasis staging. Materials and methods: A total of 567 patients (489 males and 78 females, mean age 60.9 ± 10.7 years) were enrolled in this study. Among the 567 patients, a total of 156 patients …
Detection The Frequency Of Per-1 Type Extended-Spectrum Ss-Lactamase-Producing Acinetobacter Baumannii Clinical Isolates In Turkey: A Multicenter Study, Gülşah Aşik, Mehmet Özdemi̇r, Muhammet Güzel Kurtoğlu, Server Yağci, Lütfi̇ye Öksüz, Mustafa Gül, Mücahi̇de Esra Koçoğlu, Emel Sesli̇ Çeti̇n, Adnan Seyrek, Mustafa Berktaş, Ahmet Ayyildiz, İhsan Hakki Çi̇ftci̇
Detection The Frequency Of Per-1 Type Extended-Spectrum Ss-Lactamase-Producing Acinetobacter Baumannii Clinical Isolates In Turkey: A Multicenter Study, Gülşah Aşik, Mehmet Özdemi̇r, Muhammet Güzel Kurtoğlu, Server Yağci, Lütfi̇ye Öksüz, Mustafa Gül, Mücahi̇de Esra Koçoğlu, Emel Sesli̇ Çeti̇n, Adnan Seyrek, Mustafa Berktaş, Ahmet Ayyildiz, İhsan Hakki Çi̇ftci̇
Turkish Journal of Medical Sciences
\beta-Lactamases are an important resistance mechanism in Acinetobacter baumannii. Pseudomonas extended-resistance (PER-1) type \beta-lactamase-producing strains have been reported from various geographic locations; however, PER-1 type \beta-lactamases from Turkish hospitals have not been investigated extensively. The aim of this study was to determine the prevalence of PER-1 type \beta-lactamases in A. baumannii isolates in various regions of Turkey. Materials and methods: A total of 763 clinical A. baumannii isolates were collected from 9 university hospitals and 2 state hospitals between 2008 and 2011. Molecular amplification of the OXA-51 gene from the A. baumannii genome was performed in order to verify identification …
The Comparison Of Pandemic H1n1 Igg Levels Between H1n1 Influenza-Vaccinated Healthcare Workers And Unvaccinated Healthcare Workers, Aydin Çi̇fci̇, Özlem Erol, Sali̇h Cesur, Nurkan Aksoy, Üçler Kisa
The Comparison Of Pandemic H1n1 Igg Levels Between H1n1 Influenza-Vaccinated Healthcare Workers And Unvaccinated Healthcare Workers, Aydin Çi̇fci̇, Özlem Erol, Sali̇h Cesur, Nurkan Aksoy, Üçler Kisa
Turkish Journal of Medical Sciences
To compare pandemic H1N1 (pH1N1) IgG antibody levels between healthcare workers who were vaccinated with the pH1N1 influenza vaccine and the unvaccinated healthcare workers who were selected as the control group. Materials and methods: A total of 68 healthcare workers were included in this study. Of those, 53 were adults vaccinated with the H1N1 influenza vaccine and 15 were unvaccinated. Serum samples were parsed and stored at -40 °C until they were examined. Results: Of the total 53 vaccinated healthcare workers, 16 (30.1%) were positive for IgG antibodies (titer > 11), 17 (32.0%) were negative for IgG antibodies (titer < 9), and 20 (37.7%) were borderline (titer: 9-11). Of the 15 unvaccinated healthcare workers, 1 (6.6%) was positive for IgG antibodies, 11 (73.3%) were negative for IgG antibodies, and the remaining 3 (20.0%) had borderline values (P = 0.014, P < 0.05). In both groups, there was no statistically significant difference between IgG-negative, IgG-positive, and borderline subjects in terms of age or sex. Conclusion: The IgG antibody level was higher in the vaccinated healthcare workers than among the unvaccinated healthcare workers.
A General Consideration Of The Importance Of Nutrition For Critically Ill Patients, Ersi̇n Gürkan Dumlu, Mesut Özdedeoğlu, Bi̇rkan Bozkurt, Mehmet Tokaç, Abdussamed Yalçin, Levent Öztürk, Mehmet Kiliç
A General Consideration Of The Importance Of Nutrition For Critically Ill Patients, Ersi̇n Gürkan Dumlu, Mesut Özdedeoğlu, Bi̇rkan Bozkurt, Mehmet Tokaç, Abdussamed Yalçin, Levent Öztürk, Mehmet Kiliç
Turkish Journal of Medical Sciences
Malnutrition is a common medical condition among intensive care unit patients. It should be monitored carefully, since early management of malnutrition can dramatically improve the medical condition of the patients. A general consideration of enteral feeding shows that it is much more useful than parenteral administration, because it is more physiological and poses a lower risk of hyperalimentation. Materials and methods: In this retrospective study, we scanned all files and personal information of patients hospitalized in intensive care units between 2009 and 2012 due to various medical conditions. We evaluated the nutritional status of patients with biochemical parameters that were …
The Increase Of Mean Platelet Volume In Patients With Alzheimer Disease, Emi̇ne Rabi̇a Koç, Ertuğrul Uzar, Yasemi̇n Çirak, Yasemi̇n Parlak Demi̇r, Ati̇lla İlhan
The Increase Of Mean Platelet Volume In Patients With Alzheimer Disease, Emi̇ne Rabi̇a Koç, Ertuğrul Uzar, Yasemi̇n Çirak, Yasemi̇n Parlak Demi̇r, Ati̇lla İlhan
Turkish Journal of Medical Sciences
Vascular risk factors play an important role in the progression of Alzheimer disease (AD). Mean platelet volume (MPV) is a determinant of platelet functionality and increased MPV is associated with an increased risk of vascular inflammation. Here we aimed to examine whether MPV could be used as a marker of vascular damage in AD and to discuss the relation between MPV and other vascular risk factors. Materials and methods: A total of 109 outpatients with AD and 81 healthy controls were included in this study. Diagnosis of AD was made according to defined criteria. The Turkish version of the Mini …
Comparison Of Motor Pattern Of Periodic Limb Movements In Patients With Restless Legs Syndrome And Obstructive Sleep Apnea Syndrome, Murat Gülteki̇n, Sevda İsmai̇loğullari, Murat Aksu
Comparison Of Motor Pattern Of Periodic Limb Movements In Patients With Restless Legs Syndrome And Obstructive Sleep Apnea Syndrome, Murat Gülteki̇n, Sevda İsmai̇loğullari, Murat Aksu
Turkish Journal of Medical Sciences
Periodic limb movements (PLMs) are repetitive and stereotypical movements of the lower extremities that occur during sleep. The purpose of this study was to analyze the leg muscle activity patterns in PLMs seen in restless legs syndrome (RLS) and obstructive sleep apnea syndrome (OSAS). Materials and methods: In this study, 1260 PLMs from 4 patients with RLS and 4 patients with OSAS were analyzed. The spreading and frequency characteristics of the gastrocnemius, medial hamstring, and vastus muscles were examined separately for each muscle in addition to the tibialis anterior muscle already included in the standard polysomnography recording. Results: A greater …
Evaluation Report Of Pediatric Intensive Care Units In Turkey, Benan Bayrakci, Selman Kesi̇ci̇, Tanil Kendi̇rli̇, Gökhan Kalkan, Aydin Sari, Necvan Tokmak, Gökmen Yilmaz, Orkun Baloğlu, İrfan Şencan
Evaluation Report Of Pediatric Intensive Care Units In Turkey, Benan Bayrakci, Selman Kesi̇ci̇, Tanil Kendi̇rli̇, Gökhan Kalkan, Aydin Sari, Necvan Tokmak, Gökmen Yilmaz, Orkun Baloğlu, İrfan Şencan
Turkish Journal of Medical Sciences
To collect data from throughout Turkey in order to facilitate the organization of pediatric intensive care units (PICUs), and to develop short-term immediate action plans and draft long-term strategic plans. Materials and methods: A total of 35 specialists including 17 pediatric critical care (PCC) specialists, 9 PCC fellows in training, and 9 pediatricians working in PICUs evaluated PICUs and their infrastructures, mortality rates, appropriateness of indications for PICU admissions, PICU bed numbers, and utilization of those PICU beds. Results: PICU bed numbers, PCC specialist numbers, and PICU nurse numbers are insufficient in Turkey. The high percentage of inappropriate and inefficient …
An Examination Of The Symptoms Of Anxiety And Parental Attitude In Children With Hemophilia, Osman Abali, Osman Bülent Zülfi̇kar, Sevcan Karakoç Demi̇rkaya, Hamza Ayaydin, Fuat Kircelli̇, Meltap Duman
An Examination Of The Symptoms Of Anxiety And Parental Attitude In Children With Hemophilia, Osman Abali, Osman Bülent Zülfi̇kar, Sevcan Karakoç Demi̇rkaya, Hamza Ayaydin, Fuat Kircelli̇, Meltap Duman
Turkish Journal of Medical Sciences
Hemophilia is an inherited disease with serious repercussions. Psychiatric symptoms are frequently seen in children and adolescents with hemophilia. The aim of this study was to assess symptoms of anxiety in children with hemophilia and parental attitude towards children with hemophilia. Materials and methods: 42 boys were assessed according to child and adolescent psychiatry. Anxiety symptoms and parental attitude were obtained by the State-Trait Anxiety Scale, the Self-Report for Childhood Anxiety Related Disorders (SCARED) and the Parent Attitude Research Instrument (PARI). Results: The mean age was 11.6 ± 2.5 (range; 7-16). State anxiety scores (44.02 ± 6.9) were higher than …
A Comparison Of Dysfunctional Voiding Scores Between Patients With Nocturnal Enuresis And Healthy Children, Özlem Boybeyi̇, Mustafa Kemal Aslan, Emi̇ne Gül Durmuş, İsmai̇l Özmen, Tutku Soyer
A Comparison Of Dysfunctional Voiding Scores Between Patients With Nocturnal Enuresis And Healthy Children, Özlem Boybeyi̇, Mustafa Kemal Aslan, Emi̇ne Gül Durmuş, İsmai̇l Özmen, Tutku Soyer
Turkish Journal of Medical Sciences
To compare dysfunctional voiding symptom scores (DVSSs) between enuretic children and nonenuretic controls and to investigate associated factors that may affect DVSS. Materials and methods: A questionnaire including demographic features, educational status of parents, DVSS questions, and urinary tract infection (UTI) history was designed. A total of 269 patients were included; Group 1 comprised 161 patients with no voiding symptoms and Group 2 comprised 108 patients with nocturnal enuresis (NE). Children with DVSS of greater than 8.5 were suspected to have dysfunctional voiding. The results were evaluated using SPSS 15.0 with Kruskal-Wallis and multivariate logistic regression tests. Results: The median …
Stress Indicators During General Anesthesia With Opioid Analgesics In Children, Biljana Draskovic, Danica Stanic, Anna Uram-Benka, Izabela Fabri
Stress Indicators During General Anesthesia With Opioid Analgesics In Children, Biljana Draskovic, Danica Stanic, Anna Uram-Benka, Izabela Fabri
Turkish Journal of Medical Sciences
To determine which of the applied opioid analgesics brings the most powerful blockade of the stress response with the fewest side effects in children. Materials and methods: This was a prospective, observational clinical study. The study included 150 boys, aged 2-5 years, ASA I, who underwent herniectomy or orchidopexy in day case surgery. The introduction and maintenance of anesthesia was intravenous (propofol, rocuronium, and opioids); airway was maintained by laryngeal mask and ventilation by mixture of oxygen/air. Subjects were divided into 3 groups depending on the applied opioid analgesics (fentanyl, alfentanil, remifentanil). Results: The fentanyl group had the highest blood …
Relationship Between Placental Localisation, Birth Weight, Umbilical Doppler Parameters, And Foetal Sex, Müzeyyen Duran Erdolu, Aydin Köşüş, Nermi̇n Köşüş, Gülçi̇n Di̇lmen, Hasan Kafali
Relationship Between Placental Localisation, Birth Weight, Umbilical Doppler Parameters, And Foetal Sex, Müzeyyen Duran Erdolu, Aydin Köşüş, Nermi̇n Köşüş, Gülçi̇n Di̇lmen, Hasan Kafali
Turkish Journal of Medical Sciences
The aim of this study is to examine the relationship between placental localisation, birth weight, and foetal sex. It also evaluates umbilical artery Doppler parameters and their relationship with placental localisation. Materials and methods: This is a retrospective study of 500 healthy pregnant women who gave birth at our university. All women had undergone a detailed ultrasound and Doppler examination at 20-23 weeks. The ultrasonography results of the patients were examined retrospectively. Foetal biometry, birth weight, and umbilical artery Doppler parameters were recorded and compared according to placental localisation. Results: Birth weight was significantly higher in foetuses with anteriorly located …
Optimizing Individual Treatment Outcomes In Men With Lower Urinary Tract Symptoms Using Storage Subscale Score/Total International Prostate Symptom Score (Ipss) As A New Ipss Ratio, Serkan Altintas, İsmai̇l Cenk Acar, Saadetti̇n Yilmaz Eski̇çorapçi, Ali̇ Ersi̇n Zümrütbaş, Deni̇z Bolat, Ömer Levent Tuncay, Mehmet Zafer Sinik
Optimizing Individual Treatment Outcomes In Men With Lower Urinary Tract Symptoms Using Storage Subscale Score/Total International Prostate Symptom Score (Ipss) As A New Ipss Ratio, Serkan Altintas, İsmai̇l Cenk Acar, Saadetti̇n Yilmaz Eski̇çorapçi, Ali̇ Ersi̇n Zümrütbaş, Deni̇z Bolat, Ömer Levent Tuncay, Mehmet Zafer Sinik
Turkish Journal of Medical Sciences
To evaluate the effects of the storage/total International Prostate Symptom Score (s/T) ratio on the selection and success of medical therapy in men with lower urinary tract symptoms (LUTS). Materials and methods: A total of 54 men (>45 years of age) with moderate or severe LUTS were divided into 2 groups according to the s/T ratio: Group 1 at 0.43. Tamsulosin (0.4 mg to Group 1) and tolterodine ER (4 mg to Group 2) were administered. Patients were evaluated during the 1st and 3rd months of follow-up treatment. Results: Thirty-seven (68.5%) and 17 (31.5%) patients were in Groups 1 …
A New Knot-Supporting Instrument And Knot Technique For Laparoscopic Surgery, Hasan Börekci̇, Eli̇f Börekci̇, Hakan Ak, Kürşad Zengi̇n, Tugay Atalay, Serhat Tanik
A New Knot-Supporting Instrument And Knot Technique For Laparoscopic Surgery, Hasan Börekci̇, Eli̇f Börekci̇, Hakan Ak, Kürşad Zengi̇n, Tugay Atalay, Serhat Tanik
Turkish Journal of Medical Sciences
We report here an instrument designed by Dr Hasan Börekci that provides support to the knot to facilitate knot tying in laparoscopic procedures. We call the device the 'Börekci knot-supporting instrument' and the technique 'Börekci's knot technique'. Materials and methods: To evaluate the efficacy of this instrument, 17 surgeons performing laparoscopic surgery tied 3 knots using the classical intracorporeal method and then using the intracorporeal knot-supporting instrument. The times required to tie each knot were recorded and compared statistically. Results: Comparing the 2 knotting methods, the time spent tying the knots was shorter with the knot-supporting instrument in all 3 …
Investigation Of Linezolid Resistance In Staphylococcus Epidermidis: First Reported Linezolid Resistant Coagulase Negative Staphylococcus In Turkey, Bariş Yalçin, Mehmet Burak Selek, Bayhan Bektöre, Tuğrul Hoşbul, Mustafa Özyurt
Investigation Of Linezolid Resistance In Staphylococcus Epidermidis: First Reported Linezolid Resistant Coagulase Negative Staphylococcus In Turkey, Bariş Yalçin, Mehmet Burak Selek, Bayhan Bektöre, Tuğrul Hoşbul, Mustafa Özyurt
Turkish Journal of Medical Sciences
No abstract provided.
Folate And Homocysteine Metabolisms And Their Roles In The Biochemical Basis Of Neuropsychiatry, Alpaslan Coşar, Osman Meti̇n İpci̇oğlu, Ömer Özcan, Mustafa Gültepe
Folate And Homocysteine Metabolisms And Their Roles In The Biochemical Basis Of Neuropsychiatry, Alpaslan Coşar, Osman Meti̇n İpci̇oğlu, Ömer Özcan, Mustafa Gültepe
Turkish Journal of Medical Sciences
The term 'one-carbon metabolism' is commonly used to describe 3 separate metabolic processes: folate metabolism, the homocysteine remethylation cycle, and the transsulfuration pathway. Folate metabolism concerns the biochemical reactions in which endogenous and exogenous one-carbon units are transferred to tetrahydrofolates. The remethylation cycle is used for the synthesis of methionine from homocysteine with one-carbon units that come from folate. This methionine is then used for the synthesis of S-adenosyl methionine, which is a general donor of methyl groups for many biochemical reactions in the human body. In the transsulfuration pathway, some amino acids and polypeptides, such as cystathionine, cysteine, and …
The Obesity Prevalence Of The Students Between The Ages Of 5-19 In Kütahya, Mehmet Kaya, Ayli̇n Sayan, Mustafa Bi̇ri̇nci̇, Mevlüt Yildiz, Kami̇l Türkmen
The Obesity Prevalence Of The Students Between The Ages Of 5-19 In Kütahya, Mehmet Kaya, Ayli̇n Sayan, Mustafa Bi̇ri̇nci̇, Mevlüt Yildiz, Kami̇l Türkmen
Turkish Journal of Medical Sciences
To determine the prevalence of obesity among students between the ages of 5 and 19 in Kütahya, and to determine the factors associated with obesity prevalence. Materials and methods: The population in the survey was formed of students between the ages of 5 and 19 in the schools of Kütahya. Within the scope of this survey, obesity was evaluated in accordance with the percentile values indicated in a study on the body weight and height, head circumference, and body mass index reference values of Turkish children that was published in 2008. Results: It was determined that 6.5% of the students …
Serum Amyloid A, Fetuin-A, And Pentraxin-3 Levels In Patients With Ischemic Stroke: Novel Prognostic Biomarkers?, Sevi̇lay Sezer, Fatma Uçar, Ersi̇n Kasim Ulusoy, Serpi̇l Erdoğan, Şule Bi̇len, Cevdet Züngün, Sema Uysal, Haci Kemal Erdemli̇
Serum Amyloid A, Fetuin-A, And Pentraxin-3 Levels In Patients With Ischemic Stroke: Novel Prognostic Biomarkers?, Sevi̇lay Sezer, Fatma Uçar, Ersi̇n Kasim Ulusoy, Serpi̇l Erdoğan, Şule Bi̇len, Cevdet Züngün, Sema Uysal, Haci Kemal Erdemli̇
Turkish Journal of Medical Sciences
Inflammation plays an important role in acute ischemic stroke. In this study we aimed to investigate the relationship between acute ischemic stroke and serum amyloid A, fetuin-A, and pentraxin-3 which are inflammation markers. Materials and methods: We enrolled 52 patients with acute ischemic stroke and 30 sex-matched control subjects in the study. The patients were followed for 3 months. We evaluated the common risk factors, laboratory variables, and neurological examination of stroke patients according to prognosis scales. Results: The median serum amyloid A, fetuin-A, and pentraxin-3 levels in the stroke patients were higher than in control subjects (respectively, P = …
What Is The Best Radiological Method To Predict The Actual Weight Of The Prostate?, Meti̇n Kiliç, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ali̇ Fuat Atmaca, Abdullah Erdem Canda, Mevlana Derya Balbay
What Is The Best Radiological Method To Predict The Actual Weight Of The Prostate?, Meti̇n Kiliç, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ali̇ Fuat Atmaca, Abdullah Erdem Canda, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
We compared the weight of the prostate specimen extracted after radical prostatectomy with preoperatively estimated weights of the prostate by different imaging techniques. Materials and methods: Prostate weights were estimated by transabdominal ultrasonography (TAUS), transrectal ultrasonography (TRUS), and computed tomography (CT) preoperatively before radical prostatectomy. Prostatectomy specimens were weighed postoperatively and the actual prostate weights were calculated. Statistical analyses were done using 95% confidence intervals with repeated measurement analysis of variance and intraclass correlation coefficients. Results: Of the 163 patients enrolled in the study, the mean age was 64.2 ± 6.4 (range: 45 to 76) years. The mean postoperative prostate …
Prognostic Value Of Neutrophil/Lymphocyte Ratio In Patients With Pulmonary Embolism, Umut Yücel Çavuş, Si̇nan Yildirim, Ertan Sönmez, Çağatay Ertan, Özcan Özeke
Prognostic Value Of Neutrophil/Lymphocyte Ratio In Patients With Pulmonary Embolism, Umut Yücel Çavuş, Si̇nan Yildirim, Ertan Sönmez, Çağatay Ertan, Özcan Özeke
Turkish Journal of Medical Sciences
Preliminary evidence suggests that inflammation plays a role in the development and prognosis of pulmonary embolism (PE). We used the neutrophil/lymphocyte ratio (NLR) as a measure of systemic inflammation and investigated its association with PE. Materials and methods: A total of 266 patients who were diagnosed with PE and a control group of 124 age- and sex-matched healthy subjects were included in this study. We further classified the PE patients into 2 groups: those who survived and those who died in the first 30 days. Baseline NLR was measured by dividing neutrophil count to lymphocyte count and was compared between …
Choroidal Thickness In Healthy Turkish Subjects, Erol Coşkun, Seydi̇ Okumuş, Bülent Gürler, Ramazan Yayuspayi, Burak Ören, Erdal Kaydu, Ayşegül Çömez, İbrahi̇m Erbağci
Choroidal Thickness In Healthy Turkish Subjects, Erol Coşkun, Seydi̇ Okumuş, Bülent Gürler, Ramazan Yayuspayi, Burak Ören, Erdal Kaydu, Ayşegül Çömez, İbrahi̇m Erbağci
Turkish Journal of Medical Sciences
To investigate choroidal thickness in healthy Turkish subjects. Materials and methods: Refraction, axial length (AXL) measurement, anterior chamber, and fundus examinations were performed. Eyes that had any retinal or choroidal pathology were excluded from the study. Enhanced-depth imaging optical coherence tomography was used to evaluate choroidal thickness. Results: 139 eyes from 70 subjects were investigated. The mean age, AXL, spherical equivalent refractive error (SE), and subfoveal choroidal thickness (SCT) were 34.7 ± 12.7 years, 23.31 ± 0.91 mm, -0.15 ± 1.64 diopters (D), and 326 ± 60 µm, respectively. A negative correlation was found between SCT and AXL (P = …
The Diagnostic Value Of Ischemia-Modified Albumin In The Diagnosis Of Aortic Pathology, Oğuz Eroğlu, Süha Türkmen, Ahmet Menteşe, Gökalp Altun, Süleyman Türedi̇, Umut Eryi̇ği̇t, Süleyman Caner Karahan, Abdülkadi̇r Gündüz
The Diagnostic Value Of Ischemia-Modified Albumin In The Diagnosis Of Aortic Pathology, Oğuz Eroğlu, Süha Türkmen, Ahmet Menteşe, Gökalp Altun, Süleyman Türedi̇, Umut Eryi̇ği̇t, Süleyman Caner Karahan, Abdülkadi̇r Gündüz
Turkish Journal of Medical Sciences
To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm. Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with similar demographic characteristics. Results: Mean IMA values were 0.89 ± 0.21 absorbance units (ABSU) in the aortic aneurysm group (P < 0.001), 0.70 ± 0.12 ABSU in the aortic dissection group (P < 0.001), 0.98 ± 0.23 ABSU in the aneurysm and dissection group (P < 0.001), 0.84 ± 0.16 ABSU in the aneurysm and rupture group (P < 0.001), and 0.87 ± 0.27 ABSU in the aneurysm, dissection, and rupture group (P < 0.001). Mean IMA value for the subjects in the control group was 0.62 ± 0.17 ABSU. All the differences between the aortic pathology groups' IMA values and those of the control group were statistically significant (P < 0.001). Conclusion: On the basis of the findings from this study, serum IMA levels are higher in patients with aortic pathology compared to healthy individuals. This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.
Comparison Of The Effects Of Different Percutaneous Tracheotomy Techniques On Acute Tracheal Trauma, Cengi̇z Beki̇r Demi̇rel, Hacer Haltaş, Hasan Kutluk Pampal, Yusuf Ünal, Berri̇n Işik, Mükerrem Uysal
Comparison Of The Effects Of Different Percutaneous Tracheotomy Techniques On Acute Tracheal Trauma, Cengi̇z Beki̇r Demi̇rel, Hacer Haltaş, Hasan Kutluk Pampal, Yusuf Ünal, Berri̇n Işik, Mükerrem Uysal
Turkish Journal of Medical Sciences
As it can easily be performed at the bedside with minimal morbidity, percutaneous dilatational tracheotomy (PDT) is preferred over surgical tracheotomy. The aim of this study is to compare the effects of different PDT techniques on posterior tracheal wall injury. Materials and methods: The study was conducted at the Gazi University Laparoscopy Training Center after approval was granted by the ethics committee. After sedation with xylazine/ketamine, electrocardiography, peripheral oxygen saturation, and blood pressure were monitored. Propofol was used to achieve the desired level of sedation during the procedure. There were 16 pigs, randomly allocated into 4 groups. Multiple, single, forceps, …
Increasing Resistance Of Nosocomial Acinetobacter Baumannii: Are We Going To Be Defeated?, Tümer Güven, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, Ayşe Kaya Kalem, Fatma Eser, Mehmet Akin Taşyaran
Increasing Resistance Of Nosocomial Acinetobacter Baumannii: Are We Going To Be Defeated?, Tümer Güven, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, Ayşe Kaya Kalem, Fatma Eser, Mehmet Akin Taşyaran
Turkish Journal of Medical Sciences
To investigate the change of the antibiotic resistance profiles of the nosocomial Acinetobacter baumannii isolates in intensive care units (ICUs) between the years 2008 and 2011. Materials and methods: A. baumannii isolates that were responsible for ICU-acquired nosocomial infections between 2008 and 2011 were included in the study. The susceptibility rates of the antibiotics that are mainly used in the treatment of Acinetobacter infections were compared by years. Clinical and Laboratory Standards Institute criteria were used to determine antimicrobial susceptibility. Results: There were 252 infection episodes detected in 229 hospitalized patients in the ICU that were caused by A. baumannii. …
Incidental Parathyroidectomy During Thyroid Surgery: Risk Factors, Incidence, And Outcomes, Bünyami̇ Özoğul, Müfi̇de Nuran Akçay, Abdullah Kisaoğlu, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk, Bülent Aydinli
Incidental Parathyroidectomy During Thyroid Surgery: Risk Factors, Incidence, And Outcomes, Bünyami̇ Özoğul, Müfi̇de Nuran Akçay, Abdullah Kisaoğlu, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk, Bülent Aydinli
Turkish Journal of Medical Sciences
Incidental removal of the parathyroid glands is common in some cases. In this trial, we investigated the risk factors, incidence, and outcomes associated with incidental excision of the parathyroid glands during thyroid surgery. Materials and methods: The records of patients who had undergone thyroid surgery in our department between January 2006 and December 2011 were retrospectively evaluated. Results: A total of 801 patients were enrolled in the trial. The number of incidental parathyroidectomies was determined as 19 (2.3%). Statistical evaluation revealed that sex (P > 0.05) and type of surgical operation (P > 0.05) were not associated with a significant impact on …
Puva Phototherapy-Induced Secondary Amyloidosis In Patients With Mycosis Fungoides: A Rare Adverse Effect Of Phototherapy, Itir Ebru Zemheri̇, Sidika Şeyma Özkanli, İlki̇n Zi̇ndanci, Serkan Şenol, Özge Akbulak, Fi̇li̇z Topaloğlu Demi̇r
Puva Phototherapy-Induced Secondary Amyloidosis In Patients With Mycosis Fungoides: A Rare Adverse Effect Of Phototherapy, Itir Ebru Zemheri̇, Sidika Şeyma Özkanli, İlki̇n Zi̇ndanci, Serkan Şenol, Özge Akbulak, Fi̇li̇z Topaloğlu Demi̇r
Turkish Journal of Medical Sciences
Amyloidosis is a common disorder in adults. Secondary amyloidosis in patients with mycosis fungoides (MF) after photochemotherapy with 8-methoxypsoralen followed by ultraviolet A (PUVA) treatment has not been reported. Our aim is to describe the clinical and histological features of PUVA phototherapy-induced secondary amyloidosis. Materials and methods: Sixty-one patients with MF treated with PUVA phototherapy were analyzed clinically and pathologically and by staining with Congo red and crystal violet. Results: Of 61 patients, 5 met the study criteria. Secondary amyloidosis was detected in 5 patients treated with PUVA. The secondary amyloidosis appeared after a mean of 56 exposures (range: 30-81) …
Acute Q Fever Among Febrile Patients In Zahedan, Southeastern Iran, Maliheh Metanat, Nahid Sepehri Rad, Roya Alavi-Naini, Shahram Shahreki, Batool Sharifi-Mood, Aida Akhavan, Zahra Poormotaseri
Acute Q Fever Among Febrile Patients In Zahedan, Southeastern Iran, Maliheh Metanat, Nahid Sepehri Rad, Roya Alavi-Naini, Shahram Shahreki, Batool Sharifi-Mood, Aida Akhavan, Zahra Poormotaseri
Turkish Journal of Medical Sciences
So far, few studies have been conducted on Q fever in Iran. The objective of this study was to determine the frequency of acute Q fever in febrile patients admitted to Boo-Ali Hospital in Zahedan (southeastern Iran). Materials and methods: In this study, 105 febrile patients suspected of having brucellosis were examined using indirect immunofluorescent assay kit for the detection of Coxiella burnetii IgM and IgG phase antibodies in their serum. Serum with a phase II IgG titer of =>256 and a phase II IgM titer of =>50 was predictive for acute Q fever. Additionally, a 4-fold rise …