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Full-Text Articles in Medicine and Health Sciences
A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük
A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük
Turkish Journal of Medical Sciences
Background/aim: Human endothelial cell-specific molecule-1 (endocan) is a marker of vascular endothelial dysfunction that may be used in the evaluation of inflammatory-associated atherosclerotic lesions. Endocan may be a marker for the evaluation of atherosclerosis and disease activity in rheumatoid arthritis (RA) patients.Materials and methods: We included 39 RA patients assessed according to the American College of Rheumatology/European League Against Rheumatology 2010 diagnostic criteria and recruited 30 age- and sex-matching healthy subjects for the control group.Results: Endocan values were 14.11 ± 3.27 for the RA patients and 12.10 ± 2.92 for the controls. The endocan values of the patients were significantly …
Relationship Between Plasma Ykl-40 Levels And Endothelial Dysfunction In Chronic Kidney Disease, Gül Sema Yildiran Keski̇n, Özant Helvaci, Çağri Yayla, Özge Tuğçe Paşaoğlu, Çağlar Keski̇n, Seli̇m Turgay Arinsoy, Ülver Deri̇ci̇
Relationship Between Plasma Ykl-40 Levels And Endothelial Dysfunction In Chronic Kidney Disease, Gül Sema Yildiran Keski̇n, Özant Helvaci, Çağri Yayla, Özge Tuğçe Paşaoğlu, Çağlar Keski̇n, Seli̇m Turgay Arinsoy, Ülver Deri̇ci̇
Turkish Journal of Medical Sciences
We aimed to evaluate the relationship between YKL-40 and endothelial dysfunction in chronic kidney disease. Materials and methods: Twenty-nine hemodialysis patients, 101 patients with nondialytic (stage 2, 3, 4, and 5 ND) chronic kidney disease (CKD), and 38 healthy individuals as a control group were included. YKL-40 levels were measured by ELISA. Endothelial dysfunction was indirectly measured by flow-mediated dilatation percentage (FMD) in the brachial artery. Results: YKL-40 levels were higher in CKD patients than controls and highest in HD patients (P = 0.001). FMD values were lower in nondialytic CKD patients and lowest in HD patients (P = 0.001). …
Serum Fetuin-A Is Associated With The Components Of Miac(Malnutrition, Inflammation, Atherosclerosis, Calcification) Syndrome In Different Stages, Rüya Mutluay, Ceyla Konca Değerteki̇n, Emel Işiktaş Sayilar, Ülver Deri̇ci̇, Serap Gülteki̇n, Sevi̇m Gönen, Seli̇m Turgay Arinsoy, Mahmut Şükrü Si̇ndel
Serum Fetuin-A Is Associated With The Components Of Miac(Malnutrition, Inflammation, Atherosclerosis, Calcification) Syndrome In Different Stages, Rüya Mutluay, Ceyla Konca Değerteki̇n, Emel Işiktaş Sayilar, Ülver Deri̇ci̇, Serap Gülteki̇n, Sevi̇m Gönen, Seli̇m Turgay Arinsoy, Mahmut Şükrü Si̇ndel
Turkish Journal of Medical Sciences
Background/aim: Fetuin-A, a circulating inhibitor of calcification, is a marker of inflammatory-nutritional state. We evaluated the association between serum fetuin-A levels and vascular calcification, intima-media thickness, and nutritional and inflammatory markers in different stages of chronic kidney disease (CKD). Materials and methods: CKD patients were sampled for calcium-phosphate parameters and nutritional and inflammatory markers [highly sensitive C-reactive protein (hs-CRP)], and serum fetuin-A levels. Intima-media thicknesses of the common carotid arteries (CIMT) were measured. Peripheral artery calcification scores were obtained.Results: A total of 238 patients were included in the study. Fetuin-A levels in patients with end-stage renal disease were significantly lower …