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Articles 1 - 30 of 253
Full-Text Articles in Medicine and Health Sciences
Investigation Of Treatment Efficacy Of 10% Povidone-Iodine Sclerotherapy On Ovarian Cyst Diameter: An Experimental Study, Remzi̇ Atilgan, Şehmus Pala, Tuncay Kuloğlu
Investigation Of Treatment Efficacy Of 10% Povidone-Iodine Sclerotherapy On Ovarian Cyst Diameter: An Experimental Study, Remzi̇ Atilgan, Şehmus Pala, Tuncay Kuloğlu
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was toinvestigate the effects of 10% povidone-iodine (PI) sclerotherapyon ovarian cyst diameter through an experimental study.Materials and methods: To be able to create ovarian cysts, right unilateral salpingectomy was performed on 20 Wistar albino rats. One month after the operation, the abdomens of all rats were reopened. Sixteen rats with macroscopic ovarian cysts were divided randomly into 2 groups consisting of 8 rats. Group 1 (G1): the cyst content was only aspirated. Group 2 (G2): the ovarian cyst was aspirated and then the cystic cavity was irrigated with PI. Abdomens of all rats were …
Irak-4 Rs4251481 Gene Variant: As A Risk Factor On Inflammatory Bowel Disease, Gonca Candan, Resul Kahraman, Hayri̇ye Arzu Ergen
Irak-4 Rs4251481 Gene Variant: As A Risk Factor On Inflammatory Bowel Disease, Gonca Candan, Resul Kahraman, Hayri̇ye Arzu Ergen
Turkish Journal of Medical Sciences
Background/aim: Abnormal immune response occurs in individuals who have alleles associated with innate and adaptive immune mechanisms that predispose to inflammatory bowel disease (IBD). Interleukin-1 receptor-associated kinase 4 (IRAK-4) involved in the pathway produces cytokines that initiate and maintain inflammation through Toll-like receptors and interleukin-1 receptors on the membranes of innate immune cells are stimulated with antigens. It was aimed to investigate whether IRAK-4 rs3794262 and rs4251481 polymorphisms predispose to IBD and the possible effects of these polymorphisms by examining these gene polymorphisms with the clinic and prognostic parameters of IBD.Material and methods: Real-time PCR technique was used to detect …
Long-Term Monitoring Of Graves' Disease In Children And Adolescents: A Single-Center Experience, Selma Tunç, Özge Köprülü, Hati̇ce Ortaç, Özlem Nalbantoğlu, Ceyhun Di̇zdarer, Korcan Demi̇r, Behzat Özkan
Long-Term Monitoring Of Graves' Disease In Children And Adolescents: A Single-Center Experience, Selma Tunç, Özge Köprülü, Hati̇ce Ortaç, Özlem Nalbantoğlu, Ceyhun Di̇zdarer, Korcan Demi̇r, Behzat Özkan
Turkish Journal of Medical Sciences
Background/aim: Graves' disease (GD) is more severe, requires a more complex treatment, and has a lower probability of achieving remission in children than in adults. There is no consensus on the appropriate duration of antithyroid drug (ATD) treatment. Surgical or radioactive iodine (RAI) treatments are not definitive and generally result in permanent hypothyroidism.This study's goal was examining the effectiveness of ATD treatment in children and adolescents withGD and determining the risk factors of remission and relapse.Materials and methods: This retrospective study included 45 patients (36 females and 9 males, median age 12.5 years) aged 4-18 who were diagnosed with GD …
Percutaneous Navigable Intradiscal Decompression In Treatment Of Lumbar Disc Herniation: A Single-Center Experience, Ayşegül Ceylan, Ibrahim Asik
Percutaneous Navigable Intradiscal Decompression In Treatment Of Lumbar Disc Herniation: A Single-Center Experience, Ayşegül Ceylan, Ibrahim Asik
Turkish Journal of Medical Sciences
Background/aim: Minimally invasive procedures have been increasingly used for the treatment of herniated discs. Nonsurgical interventions minimize the secondary damage to other tissues and shorten the length of hospital stay by avoiding general anesthesia. Possible complications are thermal injuries, root injury, discitis, endplate damage, dural injury, meningitis, infection, increase in pain, and muscle spasm. We aimed to evaluate the efficacy of percutaneous decompression therapy by using intradiscal navigable electrodes on pain and functional movement index in patients with herniated nucleus pulposus (HNP).Materials and methods: A total of 209 patients with protrusive lumbar disc herniation underwent percutaneous ablation decompression treatment using …
Elevated Neutrophil To Lymphocyte Ratio As An Indicator Of Secondary Erythema Nodosum, A Retrospective Observational Study, Yildiz Hayran, Ayşe Öktem, Emi̇ne Buket Şahi̇n, Pinar İncel Uysal, Nuran Alli, Başak Yalçin
Elevated Neutrophil To Lymphocyte Ratio As An Indicator Of Secondary Erythema Nodosum, A Retrospective Observational Study, Yildiz Hayran, Ayşe Öktem, Emi̇ne Buket Şahi̇n, Pinar İncel Uysal, Nuran Alli, Başak Yalçin
Turkish Journal of Medical Sciences
Background/aim: Erythema nodosum (EN) is an inflammatory disorder of subcutaneous tissue. Although etiopathogenesis of the disease is unknown, many predisposing factors such as infections, systemic disease, and drugs have been identified. Neutrophil to lymphocyte ratio (NLR) has been shown to be a novel inflammatory marker in many dermatological diseases. The aim of our study is to investigate NLR in EN patients and evaluate its relation to the underlying cause of the disease.Materials and methods: Between 2014 and 2018, clinical and laboratory data of 395 patients diagnosed with EN and 395 controls were extracted from patient files. EN patients were grouped …
Anticipatory Effect Of Execution On Observation: An Approach Using Exopinch Finger Robot, Kutluk Bi̇lge Arikan, Hassan Gol Mohammad Zadeh, Ali̇ Emre Turgut, Murat Zi̇nnuroğlu, Gözde Bayer, Zafer Günendi̇, Bülent Cengi̇z
Anticipatory Effect Of Execution On Observation: An Approach Using Exopinch Finger Robot, Kutluk Bi̇lge Arikan, Hassan Gol Mohammad Zadeh, Ali̇ Emre Turgut, Murat Zi̇nnuroğlu, Gözde Bayer, Zafer Günendi̇, Bülent Cengi̇z
Turkish Journal of Medical Sciences
Background/aim: This study aims to explore the mirror neuron system (MNS) involvement using mu (8?12 Hz)/beta (15?25 Hz) band suppression in an action observation-execution paradigm. Materials and methods: Electrophysiological (EEG) data from 16 electrodes were recorded while 8 participants observed video clips of a hand squeezing a spring. Specifically, the effect of anticipated execution on observation was studied. For this purpose, a fully actuated finger exoskeleton robot was utilized to synchronize observation and execution and to control the execution condition for the partici-pants. Anticipatory effect was created with a randomized robot accompany session. Results: The results showed that the observational …
A Comparison Of The Effects Of Mirror Therapy And Phantom Exercises On Phantom Limb Pain, Bahar Külünkoğlu, Fati̇h Erbahçeci̇, Afra Alkan
A Comparison Of The Effects Of Mirror Therapy And Phantom Exercises On Phantom Limb Pain, Bahar Külünkoğlu, Fati̇h Erbahçeci̇, Afra Alkan
Turkish Journal of Medical Sciences
Although mirror therapy (MT) and phantom exercises (PE) have been shown to reduce pain, the efficacy of these methods in terms of pain, quality of life (QoL), and psychological status (PS) has not been investigated and compared to date. The aim of this study was to determine whether there is any difference between MT and PE in the treatment of phantom limb pain (PLP).Materials and methods: Forty unilateral transtibial amputees (aged 18-45 years) participated in this study. The subjects were randomly divided into `MT group' and `PE group'. QoL was assessed using Short-Form 36 (SF-36), psychological status using the Beck …
Differentiation Between Intestinal Behçet's Disease And Crohn's Disease Based On Endoscopy, Jing Fen Ye, Jian Long Guan
Differentiation Between Intestinal Behçet's Disease And Crohn's Disease Based On Endoscopy, Jing Fen Ye, Jian Long Guan
Turkish Journal of Medical Sciences
Differentiating intestinal Behçet's disease (BD) from Crohn's disease (CD) is highly challenging, as they often mimic each other in terms of clinical manifestations. Endoscopy is an important modality for distinguishing bowel lesions. The study was designed to identify clinical manifestations that are easily confused and to evaluate the efficacy of endoscopy for distinguishing intestinal BD from CD by several overlapping signs.Materials and methods: The data from 111 patients with intestinal BD and 81 patients with CD were retrospectively analyzed. Logistic regression was applied to establish a prediction model based on endoscopic findings for the differential diagnosis. The diagnostic efficacy of …
Determination Of Medication Adherence And Related Factors Among People Living With Hiv/Aids In A Turkish University Hospital, Erdal Ceylan, Ayşegül Koç, Ahmet Çağkan İnkaya, Serhat Ünal
Determination Of Medication Adherence And Related Factors Among People Living With Hiv/Aids In A Turkish University Hospital, Erdal Ceylan, Ayşegül Koç, Ahmet Çağkan İnkaya, Serhat Ünal
Turkish Journal of Medical Sciences
Widespread use of antiretroviral treatment (ART) has led to decrease in the incidence of HIV/AIDS-related mortality. Besides the availability of ART, medication adherence is essential for treatment success. There is a scarcity of data reported from Turkey regarding ART adherence among people living with HIV/AIDS (PLWHA). Therefore, this study was undertaken to determine medication adherence and related factors among PLWHA in Turkey.Materials and methods: The sample consisted of 158 PLWHA, who were being followed up at Infectious Diseases Outpatient Clinic of Hacettepe University Hospital. Data were collected using an individual questionnaire and the Turkish version of the Morisky Medication Adherence …
The Effect Of Isotretinoin On Insulin Resistance And Adipocytokine Levels In Acne Vulgaris Patients, Gonca Soyuduru, Esra Özsoy Adişen, İlkay Özer, Ahmet Burhan Aksakal
The Effect Of Isotretinoin On Insulin Resistance And Adipocytokine Levels In Acne Vulgaris Patients, Gonca Soyuduru, Esra Özsoy Adişen, İlkay Özer, Ahmet Burhan Aksakal
Turkish Journal of Medical Sciences
Recent data draw attention to the effect of body composition, insulin resistance, and adipocytokines to acne vulgaris (AV) development. The aim of this study was to assess the association of AV with insulin resistance and adipocytokine levels and to evaluate the effect of isotretinoin on insulin resistance and adipocytokine levels. Materials and methods: In 29 AV patients and 29 healthy volunteers, body mass index (BMI) and body fat mass (BFM), lipid, adiponectin, leptin, resistin, retinol binding protein-4 (RBP4), and insulin levels were measured and insulin resistance was assessed by HOMA-IR index in serum samples taken twice from patients before and …
Evaluation Of Measles Immunity In Turkey: Is It Still A Threat?, Selda Karaayvaz, Melahat Melek Oğuz, Ufuk Beyazova, Fatma Gülay Korukluoğlu, Yasemi̇n Coşgun, Zeli̇ha Güzelküçük, Fatma Nur Baran Aksakal, Fi̇gen Şahi̇n Dağli
Evaluation Of Measles Immunity In Turkey: Is It Still A Threat?, Selda Karaayvaz, Melahat Melek Oğuz, Ufuk Beyazova, Fatma Gülay Korukluoğlu, Yasemi̇n Coşgun, Zeli̇ha Güzelküçük, Fatma Nur Baran Aksakal, Fi̇gen Şahi̇n Dağli
Turkish Journal of Medical Sciences
Background/aim: Measles is one of the important vaccine-preventable diseases with many complications in childhood. This study presents cross-sectional seroepidemiological data, beginning from neonatal cord blood in infants to children under 6 years of age, about waning of measles antibody and tries to suggest the proper time for measles immunization.Materials and methods: A total of 564 blood samples consisting of neonatal cord blood and samples taken from infants and children at ages of 6, 9, 24-48, and 49-72 months were analyzed for measles seropositivity in a period of 6 months. Results: Measles seropositivity rate was 72.5% in 109 cord blood samples, …
Il-1rn Vntr, Il-2(-330), And Il-4 Vntr Gene Polymorphisms In Patients With Chronic Rhinosinusitis With Sinonasal Polyposis, Gökhan Kuran, Hüseyi̇n Aslan, Süheyl Haytoğlu, Özge Özalp Yüreği̇r, Sevcan Tuğ Bozdoğan
Il-1rn Vntr, Il-2(-330), And Il-4 Vntr Gene Polymorphisms In Patients With Chronic Rhinosinusitis With Sinonasal Polyposis, Gökhan Kuran, Hüseyi̇n Aslan, Süheyl Haytoğlu, Özge Özalp Yüreği̇r, Sevcan Tuğ Bozdoğan
Turkish Journal of Medical Sciences
Background/aim: Sinonasal polyposis is a complex chronic disease displaying contributions from multiple genetic and environmental factors. In this study, we analyzed possible genetic factors that increase susceptibility to this widespread inflammatory disease. Materials and methods: A total of 176 adult patients, including 78 patients with sinonasal polyposis and 98 healthy controls, were analyzed for IL-1RN VNTR, IL-2(-330), and IL-4 VNTR gene polymorphisms using polymerase chain reaction and enzyme restriction.Results: IL-1RN and IL-4 VNTR polymorphisms were notably associated with sinonasal polyposis (P = 0.0001 and P = 0.036, respectively); however, regarding the IL-2(-330) gene polymorphism, no significant difference was shown between …
Canal Wall Down Versus Canal Wall Up Surgeries In The Treatment Of Middle Ear Cholesteatoma, Recep Karamert, Faki̇h Ci̇hat Eravci, Süleyman Cebeci̇, Mehmet Düzlü, Mehmet Ekrem Zorlu, Nagi̇han Gülhan Yaşar, Hakan Tutar, Mehmet Bi̇rol Uğur, Ayşe İri̇z, Yildirim Ahmet Bayazit
Canal Wall Down Versus Canal Wall Up Surgeries In The Treatment Of Middle Ear Cholesteatoma, Recep Karamert, Faki̇h Ci̇hat Eravci, Süleyman Cebeci̇, Mehmet Düzlü, Mehmet Ekrem Zorlu, Nagi̇han Gülhan Yaşar, Hakan Tutar, Mehmet Bi̇rol Uğur, Ayşe İri̇z, Yildirim Ahmet Bayazit
Turkish Journal of Medical Sciences
Background/aim: To compare outcomes of canal wall up (CWU) and canal wall down (CWD) techniques in the treatment of middle ear cholesteatoma.Materials and methods: Medical records of 76 patients who had a primary surgery due to middle ear cholesteatoma between July 2015 and November 2017 were reviewed retrospectively. Hearing thresholds, speech discrimination scores (SDS), recurrences, and revision surgeries of CWU and CWD surgeries were compared. Results: Of 76 cholesteatoma cases, 40 (52.6%) had a CWU and 36 (47.4%) had a CWD operation. Postoperatively, the mean air conduction thresholds were significantly better in CWU compared to CWD surgeries (P = 0.016). …
Fabp4 Levels In Hypothyroidism And Its Relationship With Subclinical Atherosclerosis, Mürşi̇de Tan, Hakan Korkmaz, Hüseyi̇n Aydin, Duygu Kumbul Doğuç
Fabp4 Levels In Hypothyroidism And Its Relationship With Subclinical Atherosclerosis, Mürşi̇de Tan, Hakan Korkmaz, Hüseyi̇n Aydin, Duygu Kumbul Doğuç
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to evaluate the relationship between serum fatty acid binding protein 4 (FABP4) levels and carotid intima media thickness (CIMT) in patients with hypothyroidism.Materials and methods: Forty subclinical hypothyroidism patients, 40 overt hypothyroidism patients, and 40 healthy controls were enrolled in the study. Blood pressure, body mass index, CIMT, fasting blood sugar, creatine, alanine aminotransferase, lipid parameters, insulin, free thyroxine, triiodothyronine, thyroid-stimulating hormone (TSH), thyroid peroxidase antibody (anti-TPO), thyroglobulin antibody (anti-TG), high-sensitivity C-reactive protein (Hs-CRP), and FABP4 levels of all participants were measured.Results: Serum FABP4 levels were significantly higher in patients with subclinical and …
Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k
Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Nicotinamide N-methyltransferase (NNMT) is an enzyme that is overexpressed in malignancies. NNMT expression has not been previously studied in endometrial cancer (EC). Increased phospho-Akt (pAkt) levels in response to NNMT overexpression have been reported in in vitro studies of different cancer types. We assayed NNMT expression in primary and metastatic high-grade EC and investigated the relationship of NNMT with p53, pAkt, and survival. Materials and methods: NNMT, pAkt, and p53 expressions were assayed in 100 tissue samples of benign endometria, primary EC, and metastatic EC by immunohistochemistry. Results: The NNMT immunoreactivity score was significantly higher in primary high-grade EC …
A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük
A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük
Turkish Journal of Medical Sciences
Background/aim: Human endothelial cell-specific molecule-1 (endocan) is a marker of vascular endothelial dysfunction that may be used in the evaluation of inflammatory-associated atherosclerotic lesions. Endocan may be a marker for the evaluation of atherosclerosis and disease activity in rheumatoid arthritis (RA) patients.Materials and methods: We included 39 RA patients assessed according to the American College of Rheumatology/European League Against Rheumatology 2010 diagnostic criteria and recruited 30 age- and sex-matching healthy subjects for the control group.Results: Endocan values were 14.11 ± 3.27 for the RA patients and 12.10 ± 2.92 for the controls. The endocan values of the patients were significantly …
Can We Predict Patients That Will Not Benefit From Invasive Mechanical Ventilation? A Novel Scoring System In Intensive Care: The Imv Mortality Prediction Score (Impres), Tevfi̇k Özlü, Mehtap Pehli̇vanlar Küçük, Akin Kaya, Esra Yarar, Sami̇ Cenk Kirakli, Özlem Şengören Di̇ki̇ş, Hale Kefeli̇ Çeli̇k, Serdar Özkan, Hayri̇ye Bektaş Aksoy, Ahmet Oğuzhan Küçük
Can We Predict Patients That Will Not Benefit From Invasive Mechanical Ventilation? A Novel Scoring System In Intensive Care: The Imv Mortality Prediction Score (Impres), Tevfi̇k Özlü, Mehtap Pehli̇vanlar Küçük, Akin Kaya, Esra Yarar, Sami̇ Cenk Kirakli, Özlem Şengören Di̇ki̇ş, Hale Kefeli̇ Çeli̇k, Serdar Özkan, Hayri̇ye Bektaş Aksoy, Ahmet Oğuzhan Küçük
Turkish Journal of Medical Sciences
Background/aim: The present study aimed to define the clinical and laboratory criteria for predicting patients that will not benefit from invasive mechanical ventilation (IMV) treatment and determine the prediction of mortality and prognosis of these critical ill patients. Materials and methods: The study was designed as an observational, multicenter, prospective, and cross-sectional clinical study. It was conducted by 75 researchers at 41 centers in intensive care units (ICUs) located in various geographical areas of Turkey. It included a total of 1463 ICU patients who were receiving invasive mechanical ventilation (IMV) treatment. A total of 158 parameters were examined via logistic …
The Turkish Version Of The Modified Falls Efficacy Scale: Reliability And Validity From The Viewpoint Of Balance, Ni̇lüfer Çeti̇şli̇ Korkmaz, Mehmet Duray, Esra Doğru Hüzmeli̇, Hande Şenol
The Turkish Version Of The Modified Falls Efficacy Scale: Reliability And Validity From The Viewpoint Of Balance, Ni̇lüfer Çeti̇şli̇ Korkmaz, Mehmet Duray, Esra Doğru Hüzmeli̇, Hande Şenol
Turkish Journal of Medical Sciences
Background/aim: The factors associated with fall-related self-efficacy should be addressed, especially in the elderly. The Modified Falls Efficacy Scale (MFES) is a simple instrument with good scaling properties and reliability. The aim of the present study was to determine the reliability and the validity of the Turkish version of the MFES from the viewpoint of balance.Materials and methods: In this study, 164 participants aged >65 years were included. The use of walking aids and assistive devices, history and frequency of falls in the previous year, living environment, and exercise habits were noted. Balance and risk of falling were assessed with …
Does Mammalian Target Of Rapamycin Or Sestrin 1 Protein Signaling Have A Role In Bone Fracture Healing?, Özhan Pazarci, Halef Okan Doğan, Seyran Kilinç, İsmet Yalkin Çamurcu
Does Mammalian Target Of Rapamycin Or Sestrin 1 Protein Signaling Have A Role In Bone Fracture Healing?, Özhan Pazarci, Halef Okan Doğan, Seyran Kilinç, İsmet Yalkin Çamurcu
Turkish Journal of Medical Sciences
Background/aim: Fracture healing is a complex physiological process that involves a well-orchestrated series of biological events. The mammalian target of rapamycin (mTOR) and sestrin 1 (SESN 1) play a central role in cell metabolism, proliferation, and survival. The aim of our study is to present serum mTOR and SESN 1 levels by comparing patients with or without bone fractures. It is also a guide for further research on the roles of these proteins in fracture healing. Materials and methods: A total of 34 patients (10 females, 24 males) with bone fractures and 32 controls (10 females, 22 males) participated in …
A Prospective Clinical Investigation Of The Effects Of Anti-Tnf Alpha Therapy On Exercise Capacity In Patients With Ankylosing Spondylitis, Erhan Çapkin, Seyhan Bi̇lge Keski̇n, Murat Karkucak, Ahmet Ayar
A Prospective Clinical Investigation Of The Effects Of Anti-Tnf Alpha Therapy On Exercise Capacity In Patients With Ankylosing Spondylitis, Erhan Çapkin, Seyhan Bi̇lge Keski̇n, Murat Karkucak, Ahmet Ayar
Turkish Journal of Medical Sciences
The purpose of this study was to investigate possible effects of anti-TNF alpha therapy on cardiorespiratory fitness and physical functional capacity of patients with ankylosing spondylitis (AS). Materials and methods: Twenty-eight AS patients meeting the modified New York criteria with active disease state and an equivalent number of healthy individuals as the control were prospectively enrolled. Physical working capacity and aerobic exercise capacity of the participants were determined by using cardiopulmonary exercise tests, performed before and 4 months after initiation of anti-TNF alpha therapy. Results: The mean age of the patients was 37 ± 9.1 years, and mean duration of …
Evaluation Of Myocardial Dispersion Of Repolarization In Patients With Heart Transplantation, Cengi̇z Burak, Erkan Baysal, Muhammed Süleymanoğlu, Çağri Yayla, Serkan Çay, Ümi̇t Kervan
Evaluation Of Myocardial Dispersion Of Repolarization In Patients With Heart Transplantation, Cengi̇z Burak, Erkan Baysal, Muhammed Süleymanoğlu, Çağri Yayla, Serkan Çay, Ümi̇t Kervan
Turkish Journal of Medical Sciences
The number of patients with heart transplantation has dramatically increased in the last decade. Considerable studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. We analyzed the dispersion of myocardial repolarization using electrocardiographic Tp-e interval and Tp-e/QTc ratio in patients with heart transplantation. Materials and methods: This observational study included 38 patients (12 female and 26 male) with heart transplantation and 38 well-matched controls. From electrocardiograms, Tp-e interval and Tp-e/QTc …
Evaluation Of The Efficacy Of Epiduroscopic Adhesiolysis In Failed Back Surgery Syndrome, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken
Evaluation Of The Efficacy Of Epiduroscopic Adhesiolysis In Failed Back Surgery Syndrome, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken
Turkish Journal of Medical Sciences
We aimed to compare the results of the treatment of the patients with failed back surgery syndrome (FBSS) by mechanical lysis and steroid hylase injection via epiduroscopy due to their stabilization status and to detect the effect of pathological diagnostic markers on prognosis and ongoing treatment protocol. Materials and methods: Eighty-two patients with FBSS symptoms were included. Two groups were composed as group I (stabilized) and group II (nonstabilized). All patients were evaluated using the oswestry disability index (ODI) and visual analogue scale (VAS) scores before and after treatment at 1, 3, 6, and 12 months and using the patient …
Does Chest Compression During Cardiopulmonary Resuscitation Provide Sufficient Cerebral Oxygenation?, Mehmet Aki̇f Yazar, Mehmet Bariş Açikgöz, Adnan Bayram
Does Chest Compression During Cardiopulmonary Resuscitation Provide Sufficient Cerebral Oxygenation?, Mehmet Aki̇f Yazar, Mehmet Bariş Açikgöz, Adnan Bayram
Turkish Journal of Medical Sciences
Background/aim: Some of the patients suffering from cardiac arrest (CA) remain in a chronic unconscious state in intensive care units (ICUs). The primary aim of this study was to evaluate the efficacy of chest compression (CC) on cerebral oxygenation during cardiopulmonary resuscitation (CPR). As a secondary goal, we attempted to determine the effects of regional cerebral oxygen saturation (rSO2) values on consciousness and the survival rate using the Full Outline of Unresponsiveness (FOUR) scoring method.Materials and methods: This observational preliminary study was carried out with 20 patients with CA who were hospitalized in ICUs. The rSO2 values measured by near-infrared …
Risk Factors For Rectal Colonization Of Carbapenem-Resistant Enterobacteriaceae In A Tertiary Care Hospital: A Case-Control Study From Turkey, Fatma Eser, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Fatma Yekta Ürkmez Korkmaz, Zi̇yaci̇bali̇ Açikgöz, Mehmet Akin Taşyaran
Risk Factors For Rectal Colonization Of Carbapenem-Resistant Enterobacteriaceae In A Tertiary Care Hospital: A Case-Control Study From Turkey, Fatma Eser, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Fatma Yekta Ürkmez Korkmaz, Zi̇yaci̇bali̇ Açikgöz, Mehmet Akin Taşyaran
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the risk factors of patients colonized with carbapenem-resistant Enterobacteriaceae (CRE).Materials and methods: The study was conducted between January 2010 and March 2016. The colonized group consisted of patients who had a CRE strain in their rectal swab cultures, whereas patients with negative rectal surveillance cultures for CRE who were concurrently hospitalized in the same units with the colonized group patients were included in the control group.Results: The number of patients in the colonized and the control group was 71 and 120, respectively. Both groups were evaluated for demographic and healthcare-associated characteristics. Isolated microorganisms in …
Virulence Factors And Antimicrobial Resistance In Uropathogenic Escherichiacoli Strains Isolated From Cystitis And Pyelonephritis, Hosseinali Ghazvini, Keyvan Taheri, Elahe Edalati, Ali Miri, Mansour Sedighi, Shiva Mirkalantari
Virulence Factors And Antimicrobial Resistance In Uropathogenic Escherichiacoli Strains Isolated From Cystitis And Pyelonephritis, Hosseinali Ghazvini, Keyvan Taheri, Elahe Edalati, Ali Miri, Mansour Sedighi, Shiva Mirkalantari
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the prevalence of virulence genes as well as patterns of antibiotic resistance in cystitis and pyelonephritis uropathogenic Escherichia coli (UPEC) isolates. Materials and methods: Two hundred UPEC isolates were collected from hospitalized patients with pyelonephritis (n = 50) and cystitis (n = 150) in Shafa Hospital in Iran. Antimicrobial susceptibility and ESBL production were determined with confirmatory tests. Polymerase chain reaction assay was performed to determine the prevalence of virulence genes in UPEC strains. Results: Of a total 200 UPEC isolates, the highest and lowest resistance rates to antibiotics were for …
About "Efficacy Of Bispectral Index Monitoring For Prevention Of Anesthetic Awareness And Complications During Oocyte Pick-Up Procedure", Ayşe Çi̇ğdem Tütüncü
About "Efficacy Of Bispectral Index Monitoring For Prevention Of Anesthetic Awareness And Complications During Oocyte Pick-Up Procedure", Ayşe Çi̇ğdem Tütüncü
Turkish Journal of Medical Sciences
No abstract provided.
Childhood Atopic Dermatitis: Current Developments, Treatment Approaches, And Future Expectations, Pinar Gür Çeti̇nkaya, Ümi̇t Murat Şahi̇ner
Childhood Atopic Dermatitis: Current Developments, Treatment Approaches, And Future Expectations, Pinar Gür Çeti̇nkaya, Ümi̇t Murat Şahi̇ner
Turkish Journal of Medical Sciences
Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder of childhood. Underlying factors that contribute to AD are impaired epithelial barrier, alterations in the lipid composition of the skin, immunological imbalance including increased Th2/Th1 ratio, proinflammatory cytokines, decreased T regulatory cells, genetic mutations, and epigenetic alterations. Atopic dermatitis is a multifactorial disease with a particularly complicated pathophysiology. Discoveries to date may be considered the tip of the iceberg, and the increasing number of studies in this field indicate that there are many points to be elucidated in AD pathophysiology. In this review, we aimed to illustrate the current …
Mitoxantrone-Melphalan Conditioning Regimen For Autologous Stem Cell Transplantation In Relapsed/Refractory Lymphoma, Müfi̇de Okay, Yahya Büyükaşik, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Rafi̇ye Çi̇ftçi̇ler, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Ni̇lgün Sayinalp, Osman İlhami̇ Özcebe, Hakan Göker
Mitoxantrone-Melphalan Conditioning Regimen For Autologous Stem Cell Transplantation In Relapsed/Refractory Lymphoma, Müfi̇de Okay, Yahya Büyükaşik, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Rafi̇ye Çi̇ftçi̇ler, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Ni̇lgün Sayinalp, Osman İlhami̇ Özcebe, Hakan Göker
Turkish Journal of Medical Sciences
Background/aim: High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) has become the standard approach for patients with relapsed/refractory Hodgkin's lymphoma (HL) or non-Hodgkin's lymphoma (NHL). In this study, we report the outcome of the mitoxantrone-melphalan conditioning regimen for lymphoma. Materials and methods: The study group included 53 patients who were relapsed/refractory HL (n = 14) and NHL (n = 39) and received mitoxantrone and melphalan followed by ASCT. The transplant regimen consisted of mitoxantrone (60 mg/m2) and melphalan (180 mg/m2) followed by peripheral blood stem cell infusion (PBSC). Results: Prior to high-dose chemotherapy, 37.7% of the patients were in …
Risk Factors For Coronary Artery Disease In Young Patients With Stable Angina Pectoris, Mustafa Duran, Deni̇z Elçi̇k, Sani̇ Namik Murat, Fati̇h Öksüz, İbrahi̇m Etem Çeli̇k
Risk Factors For Coronary Artery Disease In Young Patients With Stable Angina Pectoris, Mustafa Duran, Deni̇z Elçi̇k, Sani̇ Namik Murat, Fati̇h Öksüz, İbrahi̇m Etem Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: We aimed to investigate the relationship between risk factors and the presence of coronary artery disease (CAD) in a young population with stable angina pectoris (SAP).Materials and methods: A total of571 individuals younger than 60 years old, admitted to the outpatient clinic with chest pain and referred for coronary angiography between January 2015 and December 2017, were included in the study. All clinical and biochemical parameters were documented in the hospital records. Coronary angiography of patients was monitored from records. The individuals were divided into two groups. The patient group consisted of 363 individuals with at least one-vessel stenosis …
Effects Of Different Percentages Of Body Weight-Supported Treadmill Training In Parkinson's Disease: A Double-Blind Randomized Controlled Trial, Tuğba Atan, Özden Özyemi̇şci̇ Taşkiran, Ayşe Bora Tokçaer, Gülçi̇n Kaymak Karataş, Asli Karakuş Çalişkan, Belgi̇n Karaoğlan
Effects Of Different Percentages Of Body Weight-Supported Treadmill Training In Parkinson's Disease: A Double-Blind Randomized Controlled Trial, Tuğba Atan, Özden Özyemi̇şci̇ Taşkiran, Ayşe Bora Tokçaer, Gülçi̇n Kaymak Karataş, Asli Karakuş Çalişkan, Belgi̇n Karaoğlan
Turkish Journal of Medical Sciences
Background/aim: Body weight-supported treadmill training (BWSTT) might have greater effects than conventional treadmill training (TT) in neurological diseases such as Parkinson's disease (PD). The aim of this study was to evaluate the effects of different percentages of BWSTT on gait, balance, quality of life, and fatigue in PD.Materials and methods: Thirty-five patients with moderate to advanced PD were randomized into three BWSTT groups according to the supported percentage of body weight: 0% BWSTT (control group; unsupported TT), 10% BWSTT, or 20% BWSTT. Five patients were excluded due to early discharge and 30 patients completed BWSTT sessions lasting 30 min, 5 …