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Articles 31 - 60 of 137
Full-Text Articles in Medicine and Health Sciences
The Effect Of L-Tryptophan On The Heart In Rabbits Via Chronic Hypoxia, Fi̇gen Nari̇n, Nazmi̇ Nari̇n, Fatmagül Başarslan, Ali̇ Baykan, Sadetti̇n Sezer, Hülya Akgün, Aynur Akin, Mustafa Akçakuş, Hakan Ceyran
The Effect Of L-Tryptophan On The Heart In Rabbits Via Chronic Hypoxia, Fi̇gen Nari̇n, Nazmi̇ Nari̇n, Fatmagül Başarslan, Ali̇ Baykan, Sadetti̇n Sezer, Hülya Akgün, Aynur Akin, Mustafa Akçakuş, Hakan Ceyran
Turkish Journal of Medical Sciences
To evaluate the protective effect of tryptophan on an experimentally produced hypoxic myocardial injury via biochemical and pathological parameters. Materials and methods: A total of 26 rabbits were divided into 3 groups. Group 1 (n = 9) was only exposed to hypoxia. Group 2 (n = 10) was exposed to hypoxia and received L-tryptophan (200 mg/kg per day, orally for 5 days). Group 3 (n = 7) was the control group. Before the hypoxic injury and after the delivery of the medication, serum samples were taken for troponin-I, creatine kinase myocardial isoenzymes (CK-MB), lactate dehydrogenase (LDH), glutathione peroxidase (GSH-Px), superoxide …
Exposure To Continuous Darkness Leads To Atypical Symptoms Of Seasonal Affective Disorder In Rats, Çağla Ayhan İşman, Nesli̇han Toyran, Ni̇met Ünay Gündoğan
Exposure To Continuous Darkness Leads To Atypical Symptoms Of Seasonal Affective Disorder In Rats, Çağla Ayhan İşman, Nesli̇han Toyran, Ni̇met Ünay Gündoğan
Turkish Journal of Medical Sciences
Prolonged duration of nocturnal melatonin increase has been implicated in the pathogenesis of the seasonal affective disorder (SAD) winter depression. This study was designed to investigate behavioral and physiological consequences of constant dark exposure in male rats for its potential application to human affective disorders. Materials and methods: A total of 12 male Wistar-Albino rats (230-290 g) were assigned to control (LD 12:12 h; n = 6) and constant darkness (DD, 10 days; n = 6) groups. Experimental protocol included comparison of behavioral (FST, open field test, and sucrose preference) and physiological (body weight, food intake, and blood glucose level) …
Subclinical Hypothyroidism In Obese Turkish Adolescents: The Relationship With Anthropometry And Fatty Liver, Şami̇l Hizli, Nur Arslan, Ayhan Abaci, Benal Büyükgebi̇z
Subclinical Hypothyroidism In Obese Turkish Adolescents: The Relationship With Anthropometry And Fatty Liver, Şami̇l Hizli, Nur Arslan, Ayhan Abaci, Benal Büyükgebi̇z
Turkish Journal of Medical Sciences
To evaluate whether subclinical hypothyroidism (SH) is associated with anthropometry and fatty infiltration of liver in obese adolescents. Materials and methods: The adolescents attended with the complaint of obesity aged 11 to 15 years included in the study. Patients were diagnosed as obese adolescents with fatty liver. Age-, gender-, and body weight-matched obese adolescents without fatty liver seen during the same period served as controls. Clinical characteristics, laboratory parameters, and frequency of subclinical hypothyroidism (SH) of both groups were compared. Results: The study population included 218 adolescents with obesity. Of 218, 30 (13.7%) had fatty liver at ultrasonography (group 1) …
Clinical Presentation Of Breast Tuberculosis In Eastern Anatolia, S. Selçuk Atamanalp, Cemal Gündoğdu, Pinar Polat, Gürkan Öztürk, Bülent Aydinli, Durkaya Ören, Mahmut Başoğlu, M. İlhan Yildirgan
Clinical Presentation Of Breast Tuberculosis In Eastern Anatolia, S. Selçuk Atamanalp, Cemal Gündoğdu, Pinar Polat, Gürkan Öztürk, Bülent Aydinli, Durkaya Ören, Mahmut Başoğlu, M. İlhan Yildirgan
Turkish Journal of Medical Sciences
Breast tuberculosis is a very rare disease of the breast. This report aimed to review our clinical experience of 20 years and 7 cases of breast tuberculosis. Materials and methods: The records of 7 patients with breast tuberculosis were reviewed retrospectively. Results: The surgical procedure applied for breast tuberculosis comprised 1.3% of all surgical procedures of breast surgery. The mean age of the breast tuberculosis patients was 36 years, and all of the patients were female. The mean symptom duration was 12.8 months. The most common symptoms were painful breast mass in all the patients, 2 (28.6%) of whom had …
Cervical Spine Movement During Intubation Using The Airtraq® And Direct Laryngoscopy, İ. Aydin Erden, A. Gülsün Pamuk, Şennur Uzun, Serdar Geyi̇k, Saruhan Çeki̇rge, Ülkü Aypar
Cervical Spine Movement During Intubation Using The Airtraq® And Direct Laryngoscopy, İ. Aydin Erden, A. Gülsün Pamuk, Şennur Uzun, Serdar Geyi̇k, Saruhan Çeki̇rge, Ülkü Aypar
Turkish Journal of Medical Sciences
To compare 2 endotracheal intubation techniques, namely direct laryngoscopy and Airtraq®, according to their influence on cervical spine movement and intubation time and success rates, complications, and hemodynamic responses. Materials and methods: Thirty three patients without cervical spine problems were enrolled in the study. Patients were randomized into direct laryngoscopy and Airtraq® groups. Assessment of movement of the cervical spine was made by taking 3 lateral cervical spine X-rays. First, when the cervical spine was in the neutral position, second during the greatest excursion of the cervical spine, and finally, after intubation. A reference line was drawn following the dorsal …
A Bacteriological Examination Of Urine Before And After Urodynamic Testing, Defne Gümüş, Yaşar Bağdatli
A Bacteriological Examination Of Urine Before And After Urodynamic Testing, Defne Gümüş, Yaşar Bağdatli
Turkish Journal of Medical Sciences
Urodynamic studies have been associated with an increased risk of bacteriuria and symptomatic urinary tract infection (UTI) because it is applied by invasive catheterization. In this study the value of antibiotic prophylaxis in decreasing the risk of bacteriuria and symptomatic UTI has been questioned in children. Materials and methods: Urine samples of 90 patients, who were taken before and after urodynamic testing in Cerrahpaşa Faculty of Medicine Videourodynamics Laboratory of Child Surgery Department, were cultured microbiologically to determine the presence of bacteriuria. Results: The rate of bacteriuria was found statistically higher in 50 patients under trimethoprim/sulphamethoxazole and 17 under nitrofurantoin …
Trace Elements And Physical Activity In Children And Adolescents With Depression, M. Meti̇n Donma, Orki̇de Donma
Trace Elements And Physical Activity In Children And Adolescents With Depression, M. Meti̇n Donma, Orki̇de Donma
Turkish Journal of Medical Sciences
Depression is a common mental health problem among adolescents. Depressive symptoms are also important and may appear even during the preschool period. Physical activity, which may improve some mental health problems, is inversely associated with depression. Due to the presence of some clinical evidence about the relation between the use of antidepressants and suicide, there is a need for supportive agents during antidepressant therapy. Within this context, essential trace elements gain importance for further consideration. Protection of the developing brain from the negative effects of iron deficiency is important because of iron deficiency's association with poor mental development. Reactions between …
Endometrial Parameters In Ivf And Iui Administration On Elderly Women, Nafi̇ye Yilmaz, Sevtap Kiliç, Yusuf Madendağ, İlknur Madendağ, Ayli̇n Özgün, Gülnur Özakşi̇t, Sertaç Batioğlu
Endometrial Parameters In Ivf And Iui Administration On Elderly Women, Nafi̇ye Yilmaz, Sevtap Kiliç, Yusuf Madendağ, İlknur Madendağ, Ayli̇n Özgün, Gülnur Özakşi̇t, Sertaç Batioğlu
Turkish Journal of Medical Sciences
There are still controversial results about the role of endometrial thickness, pattern, volume, and vascularity in endometrial receptivity. We studied the predictivity of endometrial parameters in endometrial receptivity in over-aged, normogonadotrophic unexplained infertile women. Materials and methods: In this study, 150 women with an age range of 38-42 were included. The patients were divided into 4 groups: group 1 was applied recombinant FSH and intrauterine insemination, group 2 was applied clomiphene citrate and intrauterine insemination, group 3 was applied IVF, and group 4 (control group) was composed of fertile control patients. All patients in each study group had standard initiation …
Effect Of Passive Smoking On The Development Of Chronic Obstructive Pulmonary Disease In Southeastern Turkey, Teki̇n Yildiz, Füsun Topçu, Yusuf Çeli̇k, Levent Akyildiz, Güngör Ateş, Di̇lek Durak
Effect Of Passive Smoking On The Development Of Chronic Obstructive Pulmonary Disease In Southeastern Turkey, Teki̇n Yildiz, Füsun Topçu, Yusuf Çeli̇k, Levent Akyildiz, Güngör Ateş, Di̇lek Durak
Turkish Journal of Medical Sciences
To determine the effect of passive smoking on the development of chronic obstructive pulmonary disease (COPD) among persons who spend a long time in cafes. Materials and methods: The study sample included 348 male smokers who were older than 40 years and spend a long time in cafes. The questions were derived from the European Coal and Steel Community (ECSC) questionnaire. We also inquired about the nature of cafe visits (hours/day, visits/week, visits/month). Results: COPD was found in 18.1% (63/348 subjects) of the smokers aged >=40 years. In these 63 subjects, based on spirometry results, the rate of mild and …
Hospital-Acquired Pneumonia In Nonintensive Care Unit Wards, Meltem Avci, Onur Özgenç, Ayten Coşkuner, Berna Bozca, Levent Kidak, Gülşen Mermut, Mehmet Sezai̇ Taşbakan, Nesli̇han Genç, Gülşen Güloğlu, Alpay Ari
Hospital-Acquired Pneumonia In Nonintensive Care Unit Wards, Meltem Avci, Onur Özgenç, Ayten Coşkuner, Berna Bozca, Levent Kidak, Gülşen Mermut, Mehmet Sezai̇ Taşbakan, Nesli̇han Genç, Gülşen Güloğlu, Alpay Ari
Turkish Journal of Medical Sciences
To determine the incidence, risk factors, etiology, and antibiotic susceptibility of hospital-acquired pneumonia (HAP) in nonintensive care units (non-ICU) and nonintubated adult patients. Materials and methods: A prospective surveillance study was performed from January 2006 through December 2007 in the medical and surgical wards of the İzmir Teaching and Research Hospital. Results: During the study period, data on 57,133 patients with a total of 413,515 patient-days were analyzed. A total of 106 HAP episodes occurred in 99 patients. The infection rate per 100 patients and per 1000 patient-days was found to be 0.2% and 0.3%, respectively. HAP episodes were detected …
Psychological Characteristics Of Adolescent Suicide Attempters Presenting To A Pediatric Emergency Service, Di̇lek Di̇lli̇, Yildiz Dallar, İlyas Çakir
Psychological Characteristics Of Adolescent Suicide Attempters Presenting To A Pediatric Emergency Service, Di̇lek Di̇lli̇, Yildiz Dallar, İlyas Çakir
Turkish Journal of Medical Sciences
To determine the sociodemographic and behavioral characteristics of adolescents who attempt suicide and evaluate them by different scales. Materials and methods: The study was conducted with 116 adolescent suicide attempters and 98 age-matched healthy controls. Results: The mean age of all adolescents was 13.8 ± 1.2 years, with ages ranging from 11 to 16 years. Of these adolescents, 82.7% were girls. The total Suicide Probability Scale score was negatively correlated with the total Reasons for Living Inventory (r = -0.42, P = 0.001) and positively correlated with the Problem Solving Inventory score, which is indicative of low problem-solving capabilities (r …
Possible Role Of Toxoplasmosis In Patients With First-Episode Schizophrenia*, Mehmet Tanyüksel, Özcan Uzun, Engi̇n Araz, Özgür Koru, Cahi̇t Babür
Possible Role Of Toxoplasmosis In Patients With First-Episode Schizophrenia*, Mehmet Tanyüksel, Özcan Uzun, Engi̇n Araz, Özgür Koru, Cahi̇t Babür
Turkish Journal of Medical Sciences
To determine the possible relationship between toxoplasmosis and patients with first-episode schizophrenia (FES). Materials and methods: Seventy-three subjects with FES (15-54 years old; mean: 23.4 years) and 40 healthy individuals (20-54 years old; mean: 30.3 years) were enrolled in the study. Most of the FES patients (90.4%) and the control individuals (95.0%) were male. Specific IgG and IgM antibodies to Toxoplasma gondii were investigated by enzyme-linked immunosorbent assay (ELISA), and the total amount of antibodies was investigated with the Sabin-Feldman dye test (SFDT). Results: Compared to the control individuals, study subjects had significantly more toxoplasmosis-like symptoms and more cats in …
X-Ray Diffraction Analysis Of Urinary Tract Stones, Turgut Yapanoglu, Azam Demi̇rel, Şenol Adanur, Hi̇kmet Yüksel, Özkan Polat
X-Ray Diffraction Analysis Of Urinary Tract Stones, Turgut Yapanoglu, Azam Demi̇rel, Şenol Adanur, Hi̇kmet Yüksel, Özkan Polat
Turkish Journal of Medical Sciences
To analyze urinary tract stones obtained in our clinic using various methods and to determine the spectrum of stone composition in the Eastern Anatolia Region, Turkey. Materials and methods: A total of 300 stones were obtained at Atatürk University, Faculty of Medicine Urology Clinic through open surgery, percutaneous nephrolithotomy (PNL), ureterorenoscopy (URS), and extracorporeal shock-wave lithotripsy (ESWL) between 1 January 2005 and 30 December 2008. Stones were analyzed in the laboratory of Ankara General Directorate of Mineral Research Exploration using X-ray diffraction (XRD). Results: It was found that 218 (72.7%) of the 300 stones were calcium oxalate (CaOx); 170 (56.7%) …
Oxidative Predictors And Lipoproteins In Male Soccer Players, Faruk Yamaner
Oxidative Predictors And Lipoproteins In Male Soccer Players, Faruk Yamaner
Turkish Journal of Medical Sciences
To determine male soccer players’ lipoprotein levels, and their total antioxidant capacity, total oxidant status, oxidative stress index, and lipid hydroperoxide and lipoprotein levels after exercise. Materials and methods: The study group included 33 certificated male soccer players with an age range of 17-20 years and the control group included 53 healthy male volunteers with an age range of 18-20 years. Their total antioxidant capacity, total oxidant status, oxidative stress index, and lipid hydroperoxide and lipoprotein levels were analyzed and compared. Results: In the baseline, plasma levels, total oxidant statuses, oxidative stress indices, and lipid hydroperoxide levels were found of …
Effect Of Viscum Album On Acute Hepatic Damage Caused By Carbon Tetrachloride In Rats, Omar Mohamed Abdel-Salam, Amany Ameen Sleem, Nermeen M. Shaffie
Effect Of Viscum Album On Acute Hepatic Damage Caused By Carbon Tetrachloride In Rats, Omar Mohamed Abdel-Salam, Amany Ameen Sleem, Nermeen M. Shaffie
Turkish Journal of Medical Sciences
To investigate the effect of Viscum album, a plant used for the treatment of hepatocellular carcinoma that has immune-modulating properties, on acute hepatic injury in rats. Materials and methods: Hepatotoxicity was induced by CCl_4 orally (0.28 mL/kg). Rats received either Viscum album at 1 of 2 dose levels (0.1 or 0.2 mL/kg) once weekly subcutaneously alone or with silymarin (25 mg/kg, orally), or silymarin (25 mg/kg) once daily orally for 1 month, starting at the time of administration of CCl_4. Liver damage was assessed by determining liver serum enzyme activities and by hepatic histopathology. Results: Viscum album administration decreased the …
Insertions Of The Lateral Pterygoid Muscle To The Disc-Capsule Complex Of The Temporomandibular Joint And Condyle, Cenk Kiliç, Gühan Dergi̇n, Fati̇h Yazar, Bülent Kurt, Tunç Kutoğlu, Hasan Ozan, Hüseyi̇n Avni̇ Balcioğlu
Insertions Of The Lateral Pterygoid Muscle To The Disc-Capsule Complex Of The Temporomandibular Joint And Condyle, Cenk Kiliç, Gühan Dergi̇n, Fati̇h Yazar, Bülent Kurt, Tunç Kutoğlu, Hasan Ozan, Hüseyi̇n Avni̇ Balcioğlu
Turkish Journal of Medical Sciences
To investigate the disc-capsule complex and condyle attachments of the lateral pterygoid muscle and its variations. Materials and methods: Forty-nine temporomandibular joint (TMJ) specimens were used, obtained from 26 human cadavers. The insertion point of each muscle head was determined. The widths and lengths of the heads were measured. Results: In 32 specimens, 2-headed muscles were present, while 3 heads were observed in 17 specimens. We defined 4 different types of attachments of muscle heads. In the most common type of attachment, the upper head inserted into the disc-capsule complex and condyle, and the lower head inserted into the condyle …
Molecular Analyses Of Salmonella Serotype Typhi And Salmonella Serotype Paratyphi B Strains Isolated In Turkey, Istar Dolapçi, Bi̇rsel Erdem, Alper Tekeli̇, Ebru Us, Mehseti̇ Bayramova, Begüm Saran, Fi̇kret Şahi̇n
Molecular Analyses Of Salmonella Serotype Typhi And Salmonella Serotype Paratyphi B Strains Isolated In Turkey, Istar Dolapçi, Bi̇rsel Erdem, Alper Tekeli̇, Ebru Us, Mehseti̇ Bayramova, Begüm Saran, Fi̇kret Şahi̇n
Turkish Journal of Medical Sciences
To investigate the characteristics of Salmonella serotype Typhi and Salmonella serotype Paratyphi B, which still remain significant in Turkey. Materials and methods: Eighteen S. Typhi and 42 S. Paratyphi B strains isolated from clinical samples were investigated by plasmid profile analysis, enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR), and pulsed field gel electrophoresis (PFGE) methods. Results: Plasmid profile analysis showed that 10 out of 18 (56%) S. Typhi isolates harbored 1 to 3 plasmids, and 11 out of 42 (26.2%) S. Paratyphi B isolates harbored 1 to 4 plasmids. PFGE performed with restriction enzyme AvrII grouped both S. Typhi and …
Does Melatonin Alleviate Cold Preservation Injury Of The Liver?, Ömer Günal, Abdurrahman Coşkun, Ari̇f Aslaner, Ümran Yildirim
Does Melatonin Alleviate Cold Preservation Injury Of The Liver?, Ömer Günal, Abdurrahman Coşkun, Ari̇f Aslaner, Ümran Yildirim
Turkish Journal of Medical Sciences
To investigate the effect of melatonin added to preservation solution on liver cold ischemia. Materials and methods: Twenty male Wistar albino rats were divided equally into groups treated with University of Wisconsin (UW) solution with and without melatonin. The LDH, AST, and ACP activities of the preservation solutions were determined in samples collected at 2, 24, 36, and 48 h. Tissue malondialdehyde and heat shock protein (HSP 70) levels were also measured and a histological examination was performed at 48 h. Results: Melatonin prevented enzyme elevation, induced heat shock protein (HSP 70), and decreased lipid peroxidation effectively in comparison to …
Investigation Of Enos Gene Intron 4 A/B Vntr And Intron 23 Polymorphisms In Patients With Essential Hypertension, İdri̇s Mehmetoğlu, Gülsüm Yilmaz, Sevi̇l Kurban, Hasan Acar, M. Aki̇f Düzenli̇
Investigation Of Enos Gene Intron 4 A/B Vntr And Intron 23 Polymorphisms In Patients With Essential Hypertension, İdri̇s Mehmetoğlu, Gülsüm Yilmaz, Sevi̇l Kurban, Hasan Acar, M. Aki̇f Düzenli̇
Turkish Journal of Medical Sciences
Nitric oxide (NO) plays a major role in the regulation of vascular tone. Production of NO can be influenced by polymorphisms of the endothelial NO synthase (eNOS) gene, which may be associated with the pathogenesis of essential hypertension (EHT). Therefore, eNOS gene intron 4 a/b variable number of tandem repeats (VNTR) and intron 23 polymorphisms were investigated in patients with EHT living in a central area of Turkey. Materials and methods: The study was performed in 91 patients (34 M, 57 F) with EHT, aged 38-76 years, and 75 age- and sex-matched healthy controls (35 M, 40 F). eNOS gene …
Transthoracic Lung And Mediastinal Biopsies Obtained With The Tru-Cut Technique: 10 Years’ Experience, Şeri̇fe Savaş Bozbaş, Şule Akçay, Fi̇gen Öztürk Ergür, Cüneyt Ayteki̇n
Transthoracic Lung And Mediastinal Biopsies Obtained With The Tru-Cut Technique: 10 Years’ Experience, Şeri̇fe Savaş Bozbaş, Şule Akçay, Fi̇gen Öztürk Ergür, Cüneyt Ayteki̇n
Turkish Journal of Medical Sciences
Percutaneous needle biopsy has been used successfully in many organ systems with excellent results and few complications. In this study, we sought to evaluate percutaneous transthoracic biopsy results using a coaxial system. Materials and methods: The records of 302 patients (mean age, 63.1 years) who underwent percutaneous CT-guided coaxial cutting needle lung and mediastinal biopsy were retrospectively evaluated. Number, diameter, location of the lesions, calcification, and emphysema on lung parenchyma were noted. The number of specimens obtained, complications after the procedure, and treatment of complications were recorded. Results: From lesions identified in 270 patients on thoracic CT, a mean of …
A Novel Hand-Held Device For The Measurement Of Ocular Alignment, Uğur E. Altiparmak, Esra Karabulut, Eric R. Eggenberger
A Novel Hand-Held Device For The Measurement Of Ocular Alignment, Uğur E. Altiparmak, Esra Karabulut, Eric R. Eggenberger
Turkish Journal of Medical Sciences
The measurement of ocular alignment can be challenging and difficult to reproduce. A method for the measurement of ocular alignment with accuracy, speed, and reproducibility would be a useful clinical addition. Materials and methods: A hand-held device consisting of a rotary prism and a red Maddox rod was constructed. This was used to evaluate 18 patients with ocular misalignment and the results were compared with the ones obtained using the prism cover testing. Results: The results from the hand-held device showed a close correlation with those of the prism cover test. Conclusion: The hand-held instrument is a useful method to …
A Novel Cut-Off For Abdominal Obesity Derived From Various Anthropometric Indices To Predict Body Composition: Arm Fat Area, Betül Çi̇çek, Ahmet Öztürk, Mümtaz M. Mazicioğlu, Neri̇man İnanç, Seli̇m Kurtoğlu
A Novel Cut-Off For Abdominal Obesity Derived From Various Anthropometric Indices To Predict Body Composition: Arm Fat Area, Betül Çi̇çek, Ahmet Öztürk, Mümtaz M. Mazicioğlu, Neri̇man İnanç, Seli̇m Kurtoğlu
Turkish Journal of Medical Sciences
Determination of fat and fat-free mass is of considerable interest in evaluation of nutritional status. The aim of the present study was to determine whether using arm fat area (AFA) is helpful in identifying abdominal obesity (waist circumference > 90^{th} percentile) in Turkish children and adolescents with high risk. According to AFA ≥ 85^{th} percentile indicating overweight, we determined age- and gender-specific cut-offs from anthropometric indices. Materials and methods: This study was conducted with 5358 (2621 boys, 2737 girls) children and adolescents aged 6-17 years. Height, weight, arm span, waist circumference (WC), mid-upper arm circumference (MUAC), and triceps skinfold thickness (TSF) …
Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin
Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin
Turkish Journal of Medical Sciences
To investigate the effects of essential hypertension on QTc dispersion (QTcd) in patients with intracerebral haematoma (ICH). Materials and methods: This prospective study included adult patients presenting with acute ICH within the first 24 h of ictus to the Emergency Department (ED). On admission, following the first clinical assessment of patients, a complete 12-lead ECG and non-contrast computed tomography (CT) were obtained from each patient. Then, the patients were divided into 2 subgroups according to the presence of hypertension history. The patient groups were compared to each other as well as the control group for QTcd. Results: The study groups …
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
Turkish Journal of Medical Sciences
Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial pathogens. The present study examined the effect of microorganisms such as Escherichia coli (E. coli), Serratia marcescens (S. marcescens), Methicillin-resistant Staphylococcus aureus (MRSA), coagulase negative staphylococci (CoNS), and Candida albicans (C. albicans) on cytokine secretion in bone marrow-dendritic cells (BM-DCs). Materials and methods: The levels of cytokines in culture supernatants of the BM-DC were determined by enzyme-linked immunosorbent assay. Results: DCs stimulated by microorganisms produced large amounts of TNF-\alpha, IL-1\beta, IL-6, and IL-10. The …
Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu
Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu
Turkish Journal of Medical Sciences
After conventional aqueous disinfectant solutions, it was shown that microorganisms were still protected in hair follicles. We hypothesized that those aqueous disinfectant solutions when used in combination with alcohol may be more effective on the inhibition of recolonization of skin and therefore catheter tip colonization. Materials and methods: Skin surface samples were taken from epidural catheter insertion sites prior to catheterization, and before and after disinfection with different combinations of povidone-iodine, chlorhexidine, and alcohol. Before catheter removal, cultures were taken once more and tips of the catheters were cultured. Results: Catheter tip colonization and skin culture results of 10% povidone-iodine …
Histopathological Effects Of Chronic Fluorosis On The Liver Of Mice (Swiss Albino), Yusuf Ersan, Evren Koç, İsmai̇l Ari, Başaran Karademi̇r
Histopathological Effects Of Chronic Fluorosis On The Liver Of Mice (Swiss Albino), Yusuf Ersan, Evren Koç, İsmai̇l Ari, Başaran Karademi̇r
Turkish Journal of Medical Sciences
Fluoride intake in high doses has toxic effects on various organs. Chronic fluorosis results in tubular degenerations, inflammation, fibrosis, parenchymatous nephritis, cloudy swellings, and dilations of convoluted tubules. In addition to these effects, fluoride causes deteriorative effects on the skeleton, teeth, and soft tissues. The goal of this study was to examine the impacts of chronic fluorosis on the liver tissues of mice. Materials and methods: One control group and 3 experimental groups, each group consisting of 4 male and 4 female mice, were formed to conduct the experiment. A stock solution including 2000 ppm fluoride was prepared by solving …
Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz
Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
The resistant organisms from patients and healthcare workers (HCWs) first colonized the gastrointestinal tract before causing infections in patients. In this study, presence of risk factors for vancomycin-resistant enterococci (VRE) colonization and the prevalence of rectal carriage of VRE among HCWs and hospitalized patients in the absence of an outbreak were investigated. Design: Cross-sectional study. Setting: A 600-bed training and research hospital. Materials and methods: A total of 508 intensive-care unit (ICU) patients and HCWs in these units were included. Risk factors such as previous antibiotic use, especially vancomycin and cephalosporin, the presence of invasive devices like catheters, and co-morbid …
Thyroid Hormone Reference Intervals And The Prevalence Of Thyroid Antibodies, Aydan Çelebi̇ler, Si̇bel Bi̇lgi̇li̇, Emi̇ne Ömür Erkizan, Huri̇ye Seri̇n, Muhammet Baysal Karaca
Thyroid Hormone Reference Intervals And The Prevalence Of Thyroid Antibodies, Aydan Çelebi̇ler, Si̇bel Bi̇lgi̇li̇, Emi̇ne Ömür Erkizan, Huri̇ye Seri̇n, Muhammet Baysal Karaca
Turkish Journal of Medical Sciences
To establish new reference intervals for thyrotropin (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) on the Beckman Coulter DxI 800 in healthy Turkish adults and assess the prevalence of laboratory evidence of thyroid antibodies in this population. Materials and methods: Specimens were obtained from 619 healthy volunteers (338 females, 281 males).The study was conducted with health care professionals and their relatives, The mean age of all the subjects was 34.7 and the median was 31 years, with ages ranging from 15 to 84. Moreover, the subjects had no evidence of thyroid autoimmunity or a history of drug use, both …
Can Dynamic Multidetector Computerized Tomography Detect Renal Cell Carcinoma Subtypes?, Ayhan Di̇ri̇m, Ni̇hal Tutar, Levent Peşki̇rci̇oğlu, Hüseyi̇n Çeli̇k, Mehmet İlteri̇ş Teki̇n, Hakan Özkardeş
Can Dynamic Multidetector Computerized Tomography Detect Renal Cell Carcinoma Subtypes?, Ayhan Di̇ri̇m, Ni̇hal Tutar, Levent Peşki̇rci̇oğlu, Hüseyi̇n Çeli̇k, Mehmet İlteri̇ş Teki̇n, Hakan Özkardeş
Turkish Journal of Medical Sciences
To evaluate the efficacy of the biphasic and triphasic dynamic multidedector computerized tomography (MDCT) in the preoperative prediction of histological subtypes of renal cell carcinoma (RCC). Materials and methods: The preoperative dynamic MDCT findings of 51 patients with renal mass who had undergone nephrectomy were reviewed retrospectively. Twenty-five of the patients had biphasic (portal and excretory) and 26 had triphasic (arterial, portal, and excretory) MDCT images. Tumor size, presence of calcification, tumor-aorta attenuation values in all phases and homogeneicity of the tumor were noted for every patient. In heterogeneous tumors, the minimum and maximum attenuation values were noted to determine …
Investigation Of The Causative Agents For Community-Acquired Pneumonia In Adult Patients, Yasemi̇n Zer, Nazan Bayram, İclal Balci, Ayten Fi̇li̇z
Investigation Of The Causative Agents For Community-Acquired Pneumonia In Adult Patients, Yasemi̇n Zer, Nazan Bayram, İclal Balci, Ayten Fi̇li̇z
Turkish Journal of Medical Sciences
Community-acquired pneumonia (CAP) is a common condition in healthy people, causing morbidity and mortality worldwide despite latest advances in therapy and immunization procedures. Causative agents cannot be detected in approximately 50% of CAP episodes and therapy is initiated empirically. We aimed to determine the spectrum and frequency of the causative agents in patients with CAP in a university hospital. Materials and methods: Seventy seven adult patients hospitalized with CAP from November 2007 to March 2008 were included. CAP was diagnosed with clinical, radiological, and laboratory signs. Results: Sputum and blood cultures grew Streptococcus pneumoniae in 15 specimens; Haemophilus influenzae in …