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Medical Sciences

TÜBİTAK

Oxidative stress

2001

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Relationship Between Aging And Susceptibility To Oxidative Damage: An Assessment By Erythrocyte Membrane Proteins And Lipids, Ahmet Özaydin, İlhan Onaran, Kadi̇r Avşar, Vecdet Tezcan, Gönül Sultuybek Jan 2001

Relationship Between Aging And Susceptibility To Oxidative Damage: An Assessment By Erythrocyte Membrane Proteins And Lipids, Ahmet Özaydin, İlhan Onaran, Kadi̇r Avşar, Vecdet Tezcan, Gönül Sultuybek

Turkish Journal of Medical Sciences

Contradictory results have been reported from various studies regarding the effect of age on susceptibility to oxidative damage. Using different parameters, we carried out a comparative study on the erythrocytes and erythrocyte membranes of healthy elderly and young adults to determine how resistance to oxidative damage is affected by aging. Thin layer chromatography and polyacrylamide gel electrophoresis under denaturing conditions were used to estimate changes in membrane phospholipids and cytoskeletal proteins, respectively. Our results showed that these components of intact erythrocytes incubated with cumene hydroperoxide (CumOOH), a powerful oxidising agent, remained unchanged in both age groups. However, exposure of erythrocyte …


Effects Of Cigarette Smoking On Blood Antioxidant Status In Short-Term And Long-Term Smokers, Hüda Di̇ken, Mustafa Kelle, Cemi̇l Tümer, Basra Deni̇z, Yüksel Baylan, Abdurrahman Şermet Jan 2001

Effects Of Cigarette Smoking On Blood Antioxidant Status In Short-Term And Long-Term Smokers, Hüda Di̇ken, Mustafa Kelle, Cemi̇l Tümer, Basra Deni̇z, Yüksel Baylan, Abdurrahman Şermet

Turkish Journal of Medical Sciences

To determine the effects of cigarette smoking on blood antioxidant status and lipid peroxidation, 16 healthy male current smokers (CS) and 16 healthy male non-smokers (NS) serving as controls were studied. CS were divided into two groups: short-term smokers (STS) 35.4 ± 5.8 years of age (mean±SD), and long-term smokers (LTS) 60.9 ± 4.9 years of age. The average smoking period of STS and LTS were 8.1 ± 1.1 years (mean ±SD) and 20.5 ± 4.5 years (mean ± SD)respectively. STS and LTS had their own controls, who were NS (young NS and old NS respectively). When STS and LTS …