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Articles 1 - 30 of 108
Full-Text Articles in Medicine and Health Sciences
The Short-Term Results Of Intensive Insulin Therapy In Preadolescent Children With Type-1 Diabetes, Ayşenur Ökten, Gülay Kaya, Mukaddes Doğan Kalyoncu, Gamze Çan
The Short-Term Results Of Intensive Insulin Therapy In Preadolescent Children With Type-1 Diabetes, Ayşenur Ökten, Gülay Kaya, Mukaddes Doğan Kalyoncu, Gamze Çan
Turkish Journal of Medical Sciences
Purpose: The aim of this study was to observe the effects of and compliance with an intensive insulin regimen in preadolescent children with type-1 diabetes. Patients and methods: Eleven insulin-dependent diabetic patients, five girls and six boys aged 8 - 11 years (mean 9 years 3 months) with a mean±SD diabetes duration of 2±1.07 years, participated in this study. The results of the intensive insulin regimen were evaluated after one-year follow-up in 11 patients, and in 8 patients at 18 months. In the first year of this study we aimed to bring about higher blood glucose than is generally advised, …
Molecular Genetics Of Breast Cancer, Emel Ergül, Ali̇ Sazci
Molecular Genetics Of Breast Cancer, Emel Ergül, Ali̇ Sazci
Turkish Journal of Medical Sciences
Recent advances in molecular biology enable researchers to understand the basis of breast cancer much better and show that hereditery breast cancer may result from mutations on several specific gene loci including BRCA1, BRCA2, p53, ATM and PTEN. These genes are tumor supressor genes and although their functions are different, they are all involved in the maintenance of genomic stability after DNA damage. Mutations that impair the function of these genes may adversely affect the manner in which DNA damage is processed. It is likely that the risk of breast cancer development is increased through this mechanism. Moreover, there are …
Teucrium Polium Inhibits Nerve Conduction And Carrageenan Induced Inflammation In The Rat Skin, Jumah Shakhanbeh, O. Adigüzel
Teucrium Polium Inhibits Nerve Conduction And Carrageenan Induced Inflammation In The Rat Skin, Jumah Shakhanbeh, O. Adigüzel
Turkish Journal of Medical Sciences
The effects of acute and chronic perineural treatment of the rat saphenous nerve with Teucrium polium (L.) extract on the conduction property of primary afferent nerve fibers and carrageenan-induced skin inflammation were studied. Direct application of 2.0% T. polium extract to the nerve trunk caused immediate complete inhibition of compound action potentials (CAPs) of all types of primary afferent nerve fibers. Partial recovery of CAPs was seen in up to 37.5% of Aab-fibers, 30.4% of Ad-fibers and 32.4% for C-fibers over one hour after removal of the extract. Fifteen to twenty days after a single perineural application of 2% T. …
The Antioxidant Activity Of The Leaves Of Cydonia Vulgaris, Ali̇ Yildirim, Müni̇r Oktay, Vahi̇t Bi̇laloğlu
The Antioxidant Activity Of The Leaves Of Cydonia Vulgaris, Ali̇ Yildirim, Müni̇r Oktay, Vahi̇t Bi̇laloğlu
Turkish Journal of Medical Sciences
The antioxidant activities of water, ethanol, and ether extracts of the leaves of Cydonia vulgaris Pers. were determined by the thiocyanate method. The antioxidant activity of water extract was increased with the increasing amount of extract (200 µg-1000µg) added to the linoleic acid emulsion. Ether extract was the most effective antioxidant among the extracts. Like antioxidant activity, the reducing power of water extract was concentration dependent. However, ethanol extract was the highest in reducing power, and ether extract was the lowest. The results obtained in the present study indicate that the leaves of Cydonia vulgaris are a potential source of …
A Relation Between The Apolipoprotein E Genotypes And Microalbuminuria In Type 2 Diabetes Mellitus, Ersi̇n Akarsu, İbrahi̇m Pi̇ri̇m, İlyas Çapoğlu, Hasan Kaya, Güngör Akçay, Necdet Ünüvar
A Relation Between The Apolipoprotein E Genotypes And Microalbuminuria In Type 2 Diabetes Mellitus, Ersi̇n Akarsu, İbrahi̇m Pi̇ri̇m, İlyas Çapoğlu, Hasan Kaya, Güngör Akçay, Necdet Ünüvar
Turkish Journal of Medical Sciences
Various relations between apolipoprotein E (apo E) and diabetic nephropathy have been reported. In this study, the question of whether there is any relation between apo E genotypes and microalbuminuria in patients with type-2 diabetes mellitus was examined. Twenty-one male and 25 female patients, with ages the range of 37-62 years (mean 51.7±7.5) with type-2 diabetes mellitus were studied. The apo E genotypes were determined by PCR amplification of the 227 bp region followed by CfoI digestion to release specific band patterns. While 24 patients had microalbuminuria (microalbuminuria group), 22 patients had normoalbuminuria (normoalbuminuria group). The patients with microalbuminuria had …
Apolipoprotein-E Genotyping In Patients With Coronary Heart Disease, İbrahi̇m Pi̇ri̇m, Muhammet Fevzi̇ Polat, Ersi̇n Akarsu, Yaşar Nuri̇ Şahi̇n, Engi̇n Bozkurt
Apolipoprotein-E Genotyping In Patients With Coronary Heart Disease, İbrahi̇m Pi̇ri̇m, Muhammet Fevzi̇ Polat, Ersi̇n Akarsu, Yaşar Nuri̇ Şahi̇n, Engi̇n Bozkurt
Turkish Journal of Medical Sciences
The aim of the study was to establish apolipoprotein E genotype in the patients with coronary heart disease (CHD) who are inhabitants of the north-east of Turkey. The study involved 106 patients (70 male, 36 female; ages ranging from 37 to 69 years) who are local people and were angiocardiographically diagnosed for CHD. The risk factors such as smoking, alcohol and obesity were determined and serum triglyceride, total cholesterol, LDL and HDL were measured in the subjects. Each patient sample was apolipoprotein E genotyped, which was achieved by PCR amplification of the 227 bp region followed by Cfo I digestion …
Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley
Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley
Turkish Journal of Medical Sciences
Absorption of zinc by preterm infants from a synthetic milk labelled extrinsically with 70Zn tracer was determined by faecal monitoring. Six male preterm babies with a mean gestational age of 31±2.9 weeks and a mean birth weight of 1.23±0.24 kg were studied for three balance periods of 72 h with intervals ranging from 6 to 30 days. The babies were fed with the milk containing zinc with added 70Zn tracer. The net (NA) and true (TA) absorption, and endogenous loss (EL) of zinc were determined by the classical (chemical) balance and isotopic approaches. The mean TA, NA and EL were …
Ocular Toxocariasis With Bilateral Virtually Symmetrical Optic Nerve Head Granulomas, Gülay Güllülü, İlknur Akyol Salman, Ahmet Özbek, Nesli̇han Astam, Akin Levent
Ocular Toxocariasis With Bilateral Virtually Symmetrical Optic Nerve Head Granulomas, Gülay Güllülü, İlknur Akyol Salman, Ahmet Özbek, Nesli̇han Astam, Akin Levent
Turkish Journal of Medical Sciences
LLÜLÜ^1 İlknur AKYOL^1 Ahmet ÖZBEK^2 Neslihan ASTAM^1 Akın LEVENT^3 Departments of ^1Ophthalmology, ^2Microbiology and Clinical Microbiology, ^3Radiology, Faculty of Medicine, Atatürk University, Erzurum - TURKEY
A Case Of Bisatellited-Isodicentric Supernumerary Chromosome 15, Y. Selma Süngü, Bi̇rsen Karaman, E. Ferda Perçi̇n, Sevi̇m Balci, İlhan Sezgi̇n
A Case Of Bisatellited-Isodicentric Supernumerary Chromosome 15, Y. Selma Süngü, Bi̇rsen Karaman, E. Ferda Perçi̇n, Sevi̇m Balci, İlhan Sezgi̇n
Turkish Journal of Medical Sciences
SÜNGÜ^1 Birsen KARAMAN^2 E. Ferda PERÇİN^1 Sevim BALCI^3 İlhan SEZGİN^1 ^1Department of Medical Biology and Genetics, Faculty of Medicine, Cumhuriyet University 58140-Sivas, ^2Department of Medical Genetics, Faculty of Medicine, Istanbul University, Çapa -Istanbul, ^3Department of Pediatrics, Faculty of Medicine, Hacettepe University Ankara - TURKEY
Antifungal Activities Of Different Extracts And Echimidine-N-Oxide From Symphytum Sylvaticum Boiss. Subsp. Sepulcrale (Boiss. & Bal.) Greuter & Burdet Var. Sepulcrale, Murat Kartal, Semra Kurucu, Muhammad I. Choudary
Antifungal Activities Of Different Extracts And Echimidine-N-Oxide From Symphytum Sylvaticum Boiss. Subsp. Sepulcrale (Boiss. & Bal.) Greuter & Burdet Var. Sepulcrale, Murat Kartal, Semra Kurucu, Muhammad I. Choudary
Turkish Journal of Medical Sciences
Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.
Comparison Of Remifentanil-Propofol And Sevoflurane For Preventing Cardiovascular Response And Quality Of Recovery In Paediatric Otolaryngologic Surgery, Zeli̇ha Özer Koçak, Ali̇ Aydin Altunkan, Şebnem Atici, İsmai̇l Ci̇nel, Uğur Oral
Comparison Of Remifentanil-Propofol And Sevoflurane For Preventing Cardiovascular Response And Quality Of Recovery In Paediatric Otolaryngologic Surgery, Zeli̇ha Özer Koçak, Ali̇ Aydin Altunkan, Şebnem Atici, İsmai̇l Ci̇nel, Uğur Oral
Turkish Journal of Medical Sciences
As the practice of outpatient paediatric surgery advances, the search continues for anaesthesia that provides rapid smooth induction, stable patient haemodynamics, rapid emergence and minimal unpleasant side effects. Therefore, this study was designed to compare the haemodynamic changes, emergence and recovery characteristics of remifentanil-propofol (TIVA) and sevoflurane anaesthesia for adenoidectomy with bilateral myringotomy and insertion of tubes and/or tonsillectomy (ENT surgery) in children. Children aged 6.3±1.6 years, undergoing elective ENT surgery, were randomly assigned to receive TIVA (n=15) and sevoflurane (n=15). In both groups, anaesthesia was induced with propofol and remifentanil and maintained either with infusion of propofol-remifentanil or sevoflurane …
Production Of Monoclonal Antibody Specific For Human Hemoglobin, Selma Öztürk, Beyazit Çirakoğlu
Production Of Monoclonal Antibody Specific For Human Hemoglobin, Selma Öztürk, Beyazit Çirakoğlu
Turkish Journal of Medical Sciences
Hemoglobin is not normally present in sputum, urine or feces except in minute amounts. Demonstration of the presence of hemoglobin in these materials is an important diagnostic clue that usually implies bleeding within the respiratory, urinary or gastroentestinal tract, respectively. In this work, a hybridoma line secreting monoclonal antibody (Mab) highly specific for human hemoglobin A (hHbA) was generated by fusion of immunized BALB/c mouse splenic lymphocytes with non-secreting mouse myeloma cells followed by selection in hypoxanthine-aminopterin-thymidine (HAT) medium and the screening of culture fluids for hHb A affinity in ELISA. The Mab produced by MAM 2/3B6 is highly specific …
Flow Cytometric Analysis Of The Effects Of Methotrexate And Vepesid On The Hep-2 Cell Cycle, Ni̇zami̇ Duran, Adi̇l M. Allahverdi̇yev, Sali̇h Çeti̇ner
Flow Cytometric Analysis Of The Effects Of Methotrexate And Vepesid On The Hep-2 Cell Cycle, Ni̇zami̇ Duran, Adi̇l M. Allahverdi̇yev, Sali̇h Çeti̇ner
Turkish Journal of Medical Sciences
Objective: To determine the mechanism of action of Methotrexate and Vepesid on the HEp-2 cells isolated from human laryngeal cancer cells morphologically and flow cytometrically (G1, G2, S and PI). Materials and Methods: The HEp-2 continuous cell line was used. Cultivation of the cells was realized in EMEM medium with 10% fetal bovine serum at an atmosphere of 37ºC with 5% CO_2. Six different concentrations of Vepesid and Methotrexate were prepared by diluting with deionized water (5 µg/ml, 50 mg/ml, 500 µg/ml). The morphological and cell cycle parameters of HEp-2 cells were determined by inverted microscope and flow cytometer respectively. …
Protective Effects Of Vitamin E Selenium And Allopurinol Against Stress-Induced Ulcer Formation In Rats, Nai̇me Canoruç, Ramazan Çi̇çek, Aytaç Atamer, Mehmet Dursun, Cengi̇z Turgut, Ensari̇ Güneli̇, Fi̇kri̇ Canoruç
Protective Effects Of Vitamin E Selenium And Allopurinol Against Stress-Induced Ulcer Formation In Rats, Nai̇me Canoruç, Ramazan Çi̇çek, Aytaç Atamer, Mehmet Dursun, Cengi̇z Turgut, Ensari̇ Güneli̇, Fi̇kri̇ Canoruç
Turkish Journal of Medical Sciences
This study was carried out in the Health Research Center (DÜSAM) laboratory of Dicle University. Vitamin E, Selenium and Allopurinol were given to counteract gastric damage caused by stress in rats. In the study 64 male Sprague dawley rats were used. They were divided into 8 groups, and protective agents were applied at different doses for 8 weeks. Then, performing cold-restraint stress stomach tissues were taken out and investigated macroscopically to determine mucosal damage. Lipid peroxidation levels in the stomach specimens were determined by identifying Malondialdehyde (MDA) levels by the thiobarbituric acid method. These agents have shown protective effects against …
Effects Of Experimental Diabetes And Insulin Treatment On Rabbit Renal Morphology: A Quantitative And Qualitative Study, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu, Celal Kaloğlu, Öztürk Özdemi̇r, Semi̇h Ayan
Effects Of Experimental Diabetes And Insulin Treatment On Rabbit Renal Morphology: A Quantitative And Qualitative Study, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu, Celal Kaloğlu, Öztürk Özdemi̇r, Semi̇h Ayan
Turkish Journal of Medical Sciences
Diabetes causes metabolic defects and related vascular alterations such as atherosclerosis. These vascular alterations may also reflect the renal structural degeneration under the influence of diabetes. Therefore, the aim of the present study was to determine qualitatively and quantitatively the effect of experimental diabetes on rabbit renal cortical structure, and also to evaluate the reversal rate of the renal structural alterations by daily insulin treatment. Eighteen rabbits, bred and fed in standard laboratory conditions, were divided into 3 groups each containing 6 animals. While control group animals received no treatment, the rest were injected with a single dose of intravenous …
The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu
The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu
Turkish Journal of Medical Sciences
The cortical thickness of the mandible (CTM) and its bone mineral density may be affected by tooth extraction. There is little knowledge of how the number of teeth in the mandible affect the cortical thickness and bone mineral density of the mandible in 2 different parts. The purpose of this study was to demonstrate whether there is any relationship between the number of teeth extracted and the cortical thickness and bone mineral density of the mandible. A total of 64 cases were evaluated in this study. The patients were divided into four groups. Group 1 consisted of 24 patients who …
Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan
Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan
Turkish Journal of Medical Sciences
From prokaryotes to eukaryotes or from invertebrates to vertebrates, all organisms have developed various adaptive mechanisms to survive within a wide range of growth temperatures. An important part of the cold adaptation mechanism occurs at the level of the cytoplasmic membrane. Cold shock affects the membrane composition and organisation to maintain the optimum membrane function. Cold shock also affects cell division. The temperature downshift results in a growth lag. During the lag phase the organism changes the composition of the cytoplasmic membrane and synthesis sets of specific proteins called cold shock proteins or cold induced proteins.
Evaluation Of Temporomandibular Joint Dysfunction By Magnetic Resonanance Imaging, Mehmet Dalkiz, Emre Pakdemi̇rli̇, Bedri̇ Beydemi̇r
Evaluation Of Temporomandibular Joint Dysfunction By Magnetic Resonanance Imaging, Mehmet Dalkiz, Emre Pakdemi̇rli̇, Bedri̇ Beydemi̇r
Turkish Journal of Medical Sciences
Many diagnostic imaging techniques are available to aid clinicians, including transcranial radiography, conventional tomography, computed tomography, arthrography, single photon emission computed tomography (SPECT) imaging and magnetic resonance imaging (MRI). The aim of this study was to evaluate clinical findings and MRI features of temporomandibunlar joint (TMJ) disorders. The clinical histories of 251 patients (502 joints) with MR images were evaluated. Eight clinical variables (articular pain, clicking, locking, limitation of mouth opening, dislocation (luxation), headache (temporal, facial or neck), occlusal disharmony) and imaging findings "Normal, Anterior Disk Displacement With Reduction (ADDR), Anterior Disk Displacement Without Reduction (ADDWR) Anterior Disk Displacement With …
Evaluation Of Non-Fatal Injuries With Relation To Where Assaults Occur, Yasemi̇n Günay Balci, Songül Acar Vai̇zoğlu, Çağatay Güler
Evaluation Of Non-Fatal Injuries With Relation To Where Assaults Occur, Yasemi̇n Günay Balci, Songül Acar Vai̇zoğlu, Çağatay Güler
Turkish Journal of Medical Sciences
The aim of the present study was to determine where injuries due to violence mostly occur and to find differences (if present) among where the assaults places in 334 patients who sustained injuries due to reasons other than accidents, randomly selected from the medical records and files of those referred to the Department of Traumatology of the Council of Forensic Medicine between 1 January and 31 December 1998 in İstanbul. The majority of both the injured (82.9%) and the accused (96.3%) were males. The distribution of places where assaults occurred in the order of frequency was as follows; workplaces (37.4%), …
Effects Of Paf Antagonist Bn52021 On Systemic And Renal Oxidative Stress In Experimentally Induced Obstructive Jaundice, Nusret Akyürek, Mustafa Kerek, Erdoğan M. Sözüer, Murat Alper, Sabahatti̇n Muhtaroğlu, Mustafa Keçeli̇
Effects Of Paf Antagonist Bn52021 On Systemic And Renal Oxidative Stress In Experimentally Induced Obstructive Jaundice, Nusret Akyürek, Mustafa Kerek, Erdoğan M. Sözüer, Murat Alper, Sabahatti̇n Muhtaroğlu, Mustafa Keçeli̇
Turkish Journal of Medical Sciences
The aim of this study is to investigate the effects of PAF antagonist BN52021 on systemic and renal oxidative stress in experimentally induced obstructive jaundice. A total of 30 Wistar-Albino type rats used in the study were divided into sham, control and study groups, each consisting of ten subjects. A laparotomy was performed on the study and control groups, and the choledochus was ligated and dissected. In the sham group, the choledochus was dissected by laparotomy and not ligated. The subjects in the control group were administered physiological saline intraperiotoneally between the 2^{nd} and 7^{th} days, and subjects in the …
Large Loop Excision Of The Transformation Zone: An Outpatient Procedure, Mehmet Rafet Gazvani, Özkan Öztürk
Large Loop Excision Of The Transformation Zone: An Outpatient Procedure, Mehmet Rafet Gazvani, Özkan Öztürk
Turkish Journal of Medical Sciences
A prospective, observational study was carried out to assess the efficacy of Large Loop Excision of the Transformation Zone (LLETZ) as an outpatient procedure during the first visit of patients with abnormal cervical smears. One hundred and seven women were treated with LLETZ under local anaesthesia as an outpatient procedure at their first visit. All patients were followed up routinely with colposcopy, cytology, and also histology where appropriate for at least 6 months. In all cases, the specimens obtained were adequate for histopathological assessment, and in 103 cases (96%), the lesion had been completely excised. When compared, the degree of …
Brain Stem And Cerebral Cortex Histamine Concentrations In The Rem Sleep Deprived Rats, Hale Sayan, Ethem Geli̇r, Aydan Babül
Brain Stem And Cerebral Cortex Histamine Concentrations In The Rem Sleep Deprived Rats, Hale Sayan, Ethem Geli̇r, Aydan Babül
Turkish Journal of Medical Sciences
Histamine is a biogenic amine widely distributed in the central nervous system that acts in a neuroregulatory role in controlling the waking state. The aim of this study was to determine whether 120 h of REM sleep deprivation (REMSD) causes changes in histamine concentrations in rat brain stems and cerebral cortex areas that are involved in the homeostatic regulation of sleep. A number of rats were subjected to 120 h of REM sleep deprivation using the flower pot water tank technique. This method used to induce REMSD is believed to be stressful. To control for the stress caused by the …
Expression Of Fas Antigen And Bcl-2 Protein In Liver Tissues Of Patients With Chronic Hepatitis B, Ayşe Polat, Fazi̇let Kayaselçuk, Reyhan Eği̇lmez, İlhan Tuncer
Expression Of Fas Antigen And Bcl-2 Protein In Liver Tissues Of Patients With Chronic Hepatitis B, Ayşe Polat, Fazi̇let Kayaselçuk, Reyhan Eği̇lmez, İlhan Tuncer
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the role of apoptosis in chronic hepatitis B, and correlate it with disease severity. We studied the expression of the Fas antigen (FasAg) and Bcl-2 protein in a group of patients with chronic hepatitis B at various stages of the disease. Four liver biopsy specimens taken from the patients with chronic hepatitis B infection and five control liver tissue specimens with normal histology were studied. Liver specimens were scored for disease severity according to Knodell's hepatic activity index (HAI). The percentage of hepatic expression was evaluated semi-quantitively. Our immunohistochemical study showed that …
Relationship Between Psychopathology And Regional Cerebral Blood Flow Detected By Tc-99m Hmpao Spect In Patients With Predominantly Positive Or Negative Schizophrenic Symptoms, Nazan Aydin, Erhan Varoğlu, Mehmet Dumlu Aydin, Hati̇ce Uslu, Ali̇ Çayköylü
Relationship Between Psychopathology And Regional Cerebral Blood Flow Detected By Tc-99m Hmpao Spect In Patients With Predominantly Positive Or Negative Schizophrenic Symptoms, Nazan Aydin, Erhan Varoğlu, Mehmet Dumlu Aydin, Hati̇ce Uslu, Ali̇ Çayköylü
Turkish Journal of Medical Sciences
We investigated whether rCBF values obtained with the SPECT technique are different in schizophrenics with predominantly positive or negative symptoms and assessed the biological underpinnings of psychotic phenomena, which has been done repeatedly in the past, with somewhat varied results. Twenty-nine schizophrenic patients were examined to investigate the relationship between regional cerebral blood flow (rCBF) and psychopathology according to SANS, SAPS and BPRS scores. Using the Tc-99m HMPAO SPECT method at rest, rCBF was assessed in 15 patients with predominantly positive (group I) and 14 with predominantly negative (group II) symptoms. Ten age-matched normal healthy volunteers comprised the control group. …
Effects Of Cigarette Smoking On Blood Antioxidant Status In Short-Term And Long-Term Smokers, Hüda Di̇ken, Mustafa Kelle, Cemi̇l Tümer, Basra Deni̇z, Yüksel Baylan, Abdurrahman Şermet
Effects Of Cigarette Smoking On Blood Antioxidant Status In Short-Term And Long-Term Smokers, Hüda Di̇ken, Mustafa Kelle, Cemi̇l Tümer, Basra Deni̇z, Yüksel Baylan, Abdurrahman Şermet
Turkish Journal of Medical Sciences
To determine the effects of cigarette smoking on blood antioxidant status and lipid peroxidation, 16 healthy male current smokers (CS) and 16 healthy male non-smokers (NS) serving as controls were studied. CS were divided into two groups: short-term smokers (STS) 35.4 ± 5.8 years of age (mean±SD), and long-term smokers (LTS) 60.9 ± 4.9 years of age. The average smoking period of STS and LTS were 8.1 ± 1.1 years (mean ±SD) and 20.5 ± 4.5 years (mean ± SD)respectively. STS and LTS had their own controls, who were NS (young NS and old NS respectively). When STS and LTS …
Adenomyoma Of The Stomach Accompanying Gastric Adenocarcinoma, Sema Hücümenoğlu, Musa Zorlu, Hakan Güzel, Fati̇h Mehmet Avşar
Adenomyoma Of The Stomach Accompanying Gastric Adenocarcinoma, Sema Hücümenoğlu, Musa Zorlu, Hakan Güzel, Fati̇h Mehmet Avşar
Turkish Journal of Medical Sciences
ÜMENOĞLU^1 Musa ZORLU^2 Hakan GÜZEL^2 Fatih Mehmet AVŞAR^3 Departments of ^1Pathology, ^2General Surgery, SSK Ankara Training and Research Hospital, ^3Department of General Surgery, Ankara Numune Training and Research Hospital, Ankara - TURKEY
Efficacy Of Some Disinfectants On Embryonated Eggs Of Toxocara Canis, Hasan Ayçi̇çek, Ender Yarsan, H. Oğuz Sarimehmetoğlu, Mehmet Tanyüksel, Nogay Gi̇rgi̇nkardeşler, Mustafa Özyurt
Efficacy Of Some Disinfectants On Embryonated Eggs Of Toxocara Canis, Hasan Ayçi̇çek, Ender Yarsan, H. Oğuz Sarimehmetoğlu, Mehmet Tanyüksel, Nogay Gi̇rgi̇nkardeşler, Mustafa Özyurt
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the efficacy of various disinfectants in different concentrations against embryonated Toxocara canis eggs. For this purpose, 2.5%, 5%, 7.5%, and 10% iodine, 2% glutaraldehyde, 10% benzalkonium chloride, 7% sodium hypochloride, 1% potassium permanganate, 70% ethyl alcohol, 10% potassium hydroxide and 3% phenol solutions were used as the disinfectants. This study was performed both in vitro and in-vivo. In the in vitro experiment, T. canis eggs were treated with disinfectant solutions in different time intervals, and larval motility was observed under X400 magnification with an inverted microscope. Microscopic examinations revealed that T. canis …
Sandwich-Type Enzyme Immunoassay For Amyloid A4 Protein In Cerebrospinal Fluid From Patients With Head Trauma, İbrahi̇m Pi̇ri̇m
Sandwich-Type Enzyme Immunoassay For Amyloid A4 Protein In Cerebrospinal Fluid From Patients With Head Trauma, İbrahi̇m Pi̇ri̇m
Turkish Journal of Medical Sciences
The aim of this study was to design a simple method for detecting the amyloid A4 protein in the cerebrospinal fluid (CSF) of patients who had severe brain trauma caused by traffic or other accidents and to evaluate its diagnostic and prognostic value. For this purpose, a sandwich type ELISA assay was used. A4, a 4kDa protein of 39-43 amino acids, is a metabolic product of a membrane-spanning, 695-770 aa, precursor molecule, the b-amyloid precursor protein (b-APP). The polyclonal rabbit antibody against synthetic A4 protein (1-40 residues) was used as an immobilized antibody. A mouse monoclonal antibody against synthetic A4 …
Biochemical Bone Markers In Prostate Cancer Patients With Local And Advanced Bone Metastates, Hülya Aksoy, Yilmaz Aksoy, Fati̇h Akçay, İsa Özbey
Biochemical Bone Markers In Prostate Cancer Patients With Local And Advanced Bone Metastates, Hülya Aksoy, Yilmaz Aksoy, Fati̇h Akçay, İsa Özbey
Turkish Journal of Medical Sciences
In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-specific alkaline phosphatase activities and serum prostate specific antigen (PSA). This study included 20 patients with benign prostate hyperplasia (BPH) and 23 patients with carcinoma, 11 of had with bone metastases. DPD excretion in urine was significantly greater in prostate cancer patients with bone metastasis than in those with localised prostate cancer or BPH (p0.05). The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean …
Perioperative Oral Supplement With Immunonutrients In Gastrointestinal Cancer Patients, Ni̇hal Zeki̇ye Erdem, İ. Hakan Kulaçoğlu, Mehtap Akci̇l Temel, Ahmet Çinar Yasti, Nuri̇ Aydin Kama, Nazan Bozkurt
Perioperative Oral Supplement With Immunonutrients In Gastrointestinal Cancer Patients, Ni̇hal Zeki̇ye Erdem, İ. Hakan Kulaçoğlu, Mehtap Akci̇l Temel, Ahmet Çinar Yasti, Nuri̇ Aydin Kama, Nazan Bozkurt
Turkish Journal of Medical Sciences
Significant benefits have been gained with pre or peri-operative nutritional support in surgical patients with malnutrition. Recent studies have also shown that some enteral formulas including certain nutrients like glutamine could provide more benefit than the standard formulas. In this prospective-randomized study, the effects of perioperative oral supplement with enteral formulas containing glutamine in comparison with a standard enteral formula in patients who were operated on for GI malignancies were examined. Thirty-two patients were divided into two groups: the study group was given oral supplement with an elemental diet (Alitraq®) for 7 days preoperatively and 10 days postoperatively as 30-35% …