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Articles 1 - 30 of 73
Full-Text Articles in Medicine and Health Sciences
Horner´S Syndrome Post-Excision Of A Huge Cervical Sympathetic Chain Schwannoma, Sedat Aydin, Ari̇f Şanli, Ömer Taşdemi̇r, Ayli̇n Ege Gül
Horner´S Syndrome Post-Excision Of A Huge Cervical Sympathetic Chain Schwannoma, Sedat Aydin, Ari̇f Şanli, Ömer Taşdemi̇r, Ayli̇n Ege Gül
Turkish Journal of Medical Sciences
Schwannoma of the cervical sympathetic chain is a rare nerve tumor. These lesions typically present as an asymptomatic neck mass and are easily mistaken for a carotid body tumor during the initial work-up. In this report, a rarely seen huge cervical sympathetic chain schwannoma case, who experienced partial Horner´s syndrome postoperatively, is presented. We report a case of schwannoma on the cervical sympathetic chain, which to our knowledge is the largest reported in the current literature.
Excretion Rate And Composition Of Skin Surface Lipids On The Foreheads Of Adult Males With Type Iv Hyperlipoproteinemia, Tayfun Güldür, Ni̇hayet Bayraktar, Özgür Kaynar, Gülçi̇n Beker, Muzaffer Koçer, Hamdi̇ Özcan
Excretion Rate And Composition Of Skin Surface Lipids On The Foreheads Of Adult Males With Type Iv Hyperlipoproteinemia, Tayfun Güldür, Ni̇hayet Bayraktar, Özgür Kaynar, Gülçi̇n Beker, Muzaffer Koçer, Hamdi̇ Özcan
Turkish Journal of Medical Sciences
Aim: Most of the lipids of the skin surface come from the sebaceous glands, which secrete an oily substance called sebum. Some of the sebum lipids are synthesized by sebaceous cells while some are reported to be derived from the plasma. The role of blood lipoproteins in sebum secretion rate and composition is unclear. To this end, excretion rate and composition of skin surface lipids in normo- and type IV hyperlipoproteinemic adult male subjects were compared. Materials and Methods: Quantitative analysis of skin surface lipids of subjects with type IV hyperlipoproteinemia (n:21) and normolipoproteinemia (n:15) was performed by three successive …
Perioperative Deaths In A Nigerian Tertiary Teaching Hospital, Chibundu E. Ohanaka, Charles O. Imarengiaye
Perioperative Deaths In A Nigerian Tertiary Teaching Hospital, Chibundu E. Ohanaka, Charles O. Imarengiaye
Turkish Journal of Medical Sciences
Aim: Perioperative deaths may be categorized into avoidable and non-avoidable. An audit of such deaths should be carried out periodically with a view to improving the standard of clinical practice. Materials and Methods: The master registry of the main theater of the hospital was examined to identify all deaths that occurred within the main theater environment (reception, operating room, and recovery room) over a five-year period (January 2000- December 2004). Patients’ ages, sex and timing of surgery (elective or emergency), American Society of Anesthesiologists (ASA) status and the diagnosis were noted. The diagnosis was further categorized in relation to the …
K26 Antigen From L. Infantum Mon1: Sequence Based Function-Localization Analysis, Behrooz Darbani, Mahmoud Toorchi, Safar Farajnia, Seyyed Abolghasem Mohammadi, C. Neal Stewart
K26 Antigen From L. Infantum Mon1: Sequence Based Function-Localization Analysis, Behrooz Darbani, Mahmoud Toorchi, Safar Farajnia, Seyyed Abolghasem Mohammadi, C. Neal Stewart
Turkish Journal of Medical Sciences
No abstract provided.
Is There A Correlation Between Extroversion Personality Characteristics Of Medical Students And Awareness Of Works Of Art?, Sare Alkan, Musaci̇de Zehra Ordulu, Yi̇ği̇t Sezer, Emi̇n Soyer, Di̇lek Aslan, İskender Sayek
Is There A Correlation Between Extroversion Personality Characteristics Of Medical Students And Awareness Of Works Of Art?, Sare Alkan, Musaci̇de Zehra Ordulu, Yi̇ği̇t Sezer, Emi̇n Soyer, Di̇lek Aslan, İskender Sayek
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to assess the relation between extroversion personality characteristics and awareness of works of art among a group of university students. Materials and Methods: One hundred thirty-five phase II students of the Medical Faculty of Hacettepe University registered in the 2005-2006 academic year participated in this descriptive study. In order to assess extroversion personality characteristics, Eysenck Extroversion Personality Scale was used. For determining awareness of works of art on the campus, researchers photographed selected works of arts and presented them for evaluation by the participants in a questionnaire. Four categories were determined as follows: category …
Effect Of Montelukast Treatment On Serum Paraoxonase Activity In Asthmatic Children, Murat Can, A. Görkem Mungan, Şerefden Açikgöz, Bi̇rol Yüksel, Selda Demi̇rtaş, Nazan Tomaç
Effect Of Montelukast Treatment On Serum Paraoxonase Activity In Asthmatic Children, Murat Can, A. Görkem Mungan, Şerefden Açikgöz, Bi̇rol Yüksel, Selda Demi̇rtaş, Nazan Tomaç
Turkish Journal of Medical Sciences
Montelukast, widely used in the treatment of asthma, is a selective and potent oral cysteinyl leukotriene-1 receptor antagonist. In this study, we investigated the effects of montelukast on oxidative stress and antioxidant defense in childhood asthma by measuring malondialdehyde and the paraoxonase activity. Twenty-five children with mild to moderate atopic asthma and 25 nonatopic children as controls were enrolled in the study. Asthmatic children were treated with montelukast, 5 mg tablets, for one month. Serum paraoxonase, malondialdehyde and high-density lipoprotein (HDL) cholesterol levels were measured before and after treatment. Serum paraoxonase and paraoxonase/HDL ratios were significantly increased after montelukast treatment. …
Comparison Of The Antibacterial Effects Of Two Local Anesthetics: Lidocaine And Articaine, Kadi̇r Kaya, Seyyal Rota, Bora Doğan, Gi̇zem Kökten, Berri̇n Günaydin, Gülendam Bozdayi
Comparison Of The Antibacterial Effects Of Two Local Anesthetics: Lidocaine And Articaine, Kadi̇r Kaya, Seyyal Rota, Bora Doğan, Gi̇zem Kökten, Berri̇n Günaydin, Gülendam Bozdayi
Turkish Journal of Medical Sciences
Aim: The antibacterial effect of lidocaine has been studied widely, but the effect of articaine has not yet been evaluated. We aimed to investigate whether commercially available articaine possesses bactericidal or bacteriostatic effect in comparison with lidocaine in a prospective laboratory setting. Materials and Methods: The antibacterial effects of articaine and lidocaine were studied on Pseudomonas aeruginosa ATCC27853, Staphylococcus aureus ATCC25923, Escherichia coli ATCC35218, and Proteus mirabilis ATCC7002 strains and a patient isolate of Serratia marcescens. For this study, 2% lidocaine HCl and articaine HCl were diluted to 10, 5, 2.5, 1.25, 0.625, 0.312, 0.156, and 0.078 mg ml^{-1} concentrations …
Risk Factors For Fecal Carriage Of Extended-Spectrum Beta-Lactamase Producing Escherichia Coli And Klebsiella Spp. In The Community, Özlem Kurt Azap, Hande Arslan, Sedef Ö. Karaman, Turhan Togan
Risk Factors For Fecal Carriage Of Extended-Spectrum Beta-Lactamase Producing Escherichia Coli And Klebsiella Spp. In The Community, Özlem Kurt Azap, Hande Arslan, Sedef Ö. Karaman, Turhan Togan
Turkish Journal of Medical Sciences
Aim: Community-acquired infections caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria are an emerging problem. Digestive tract colonization is a prerequisite for infections by ESBL-producing microorganisms. The aim of this study was to determine the prevalence of and risk factors for fecal carriage of ESBL-producing Escherichia coli (E. coli) or Klebsiella spp. in the community. Materials and Methods: A total of 928 stool samples admitted to the laboratory during a four-month period were included in the study. Samples were diluted in saline and cultured in two EMB agar plates supplemented with either 1 µg/ml cefotaxime or 1 µg/ml ceftazidime. All isolates that …
The Role Of Periodontal Disease On Acute Phase Proteins In Patients With Coronary Heart Disease And Diabetes, Gonca Çayir Keleş, Burcu Özkan Çeti̇nkaya, Selen Burçak Şi̇mşek, Di̇yar Köprülü, Hakki Kahraman
The Role Of Periodontal Disease On Acute Phase Proteins In Patients With Coronary Heart Disease And Diabetes, Gonca Çayir Keleş, Burcu Özkan Çeti̇nkaya, Selen Burçak Şi̇mşek, Di̇yar Köprülü, Hakki Kahraman
Turkish Journal of Medical Sciences
Aims: Chronic infections such as periodontal disease (PD) have been suggested to be a risk factor for coronary heart disease (CHD). Elevated levels of acute phase proteins are associated with increased risk for cardiovascular events in both healthy individuals and patients with known CHD. This study aimed to investigate the role of PD on C-reactive protein (CRP) and fibrinogen levels in patients with either CHD or type 2 diabetes. Materials and Methods: 80 subjects were evaluated in four groups: individuals with CHD+PD (group 1; n: 20), individuals with type 2 diabetes+PD (group 2; n: 20), individuals with PD without any …
Water Sorption And Solubility Of Different Luting And Restorative Dental Cements, Fi̇li̇z Keyf, S. Hakan Tuna, Murat Şen, Agnes Safrany
Water Sorption And Solubility Of Different Luting And Restorative Dental Cements, Fi̇li̇z Keyf, S. Hakan Tuna, Murat Şen, Agnes Safrany
Turkish Journal of Medical Sciences
Aim: The purpose of this study was to compare the water sorption and solubility of four provisional, three permanent luting cements and five restorative cements. Methods: A split ring mould was fabricated for the preparation of specimen discs which were 15.0 mm in diameter and 1.5 mm thick. All specimens were manipulated according to the manufacturer's instructions and then subjected to water sorption and solubility tests. Data were analysed with Wilcoxon Signed Ranks Test. Scanning electron microscopy was used to evaluate surface topography and roughness. Results: All tested materials demonstrated different degrees of sorption and solubility. The difference between sorption …
Brain Perfusion Single-Photon Emission Computed Tomography Findings In A Patient With Aicardi Syndrome, Mustafa Aydin, Tansel Ansal Balci, Ni̇met Kabakuş
Brain Perfusion Single-Photon Emission Computed Tomography Findings In A Patient With Aicardi Syndrome, Mustafa Aydin, Tansel Ansal Balci, Ni̇met Kabakuş
Turkish Journal of Medical Sciences
Aicardi syndrome is a rare X-linked dominant genetic disorder characterized by infantile spasms, agenesis or hypogenesis of the corpus callosum, and chorioretinal lacunae. There remain many unresolved questions regarding the clinical features of this disorder. Recent advancements in neuroimaging techniques have allowed us to obtain information about brain development and perfusion. Thus, we present herein the brain single-photon emission computed tomography (SPECT) findings in a 15-month-old female with Aicardi syndrome, which revealed that perfusion had shifted from the posterior to anterior regions. Furthermore, the right temporal lobe was not visualized, while significant hypoperfusion was determined on the occipital regions and …
The Role Of Heart-Type Fatty Acid-Binding Protein (H-Fabp) In Acute Myocardial Infarction (Ami) Compared To Conventional Cardiac Biochemical Markers, Hati̇ce Paşaoğlu, Ebru Ofluoğlu, Mustafa İlhan, Ati̇ye Çengel, Murat Özdemi̇r, Emre Durakoğlugi̇l, Murat Erden
The Role Of Heart-Type Fatty Acid-Binding Protein (H-Fabp) In Acute Myocardial Infarction (Ami) Compared To Conventional Cardiac Biochemical Markers, Hati̇ce Paşaoğlu, Ebru Ofluoğlu, Mustafa İlhan, Ati̇ye Çengel, Murat Özdemi̇r, Emre Durakoğlugi̇l, Murat Erden
Turkish Journal of Medical Sciences
Aim: To investigate the clinical implications of serum heart-type fatty acid-binding protein (H-FABP) compared to myoglobin, cardiac troponin I (cTnI), and creatine kinase MB isoenzyme (CK-MB) in patients with early phase acute myocardial infarction (AMI). Material and Methods: Patients were grouped clinically according to the American College of Cardiology/European Society of Cardiology new definition of myocardial infarction (MI) and by clinician diagnosis of MI. Serum concentrations of H-FABP, myoglobin, cTnI, and CK-MB were determined in 21 patients with AMI and 44 non-AMI patients. From each patient 3 blood samples were obtained 1-2, 3, and 6 h after the onset chest …
Development Of A Highly Sensitive Elisa For Quantification Of Hepatitis B Virus (Hbv) Surface Antigen (Hbsag), Resul Karakuş, Lati̇fe Arzu Aral, Bi̇lkay Baştürk, Cemaletti̇n Aybay
Development Of A Highly Sensitive Elisa For Quantification Of Hepatitis B Virus (Hbv) Surface Antigen (Hbsag), Resul Karakuş, Lati̇fe Arzu Aral, Bi̇lkay Baştürk, Cemaletti̇n Aybay
Turkish Journal of Medical Sciences
Background: Hepatitis B Virus (HBV) infection is of global importance and many studies are aimed to develop more sensitive diagnostic tools and improve therapeutic options. HBV infection is diagnosed and followed-up basically by serological studies, among which the enzyme-linked immunosorbent assay (ELISA) is widely used. Aim: To develop a sensitive HBsAg ELISA for both research and diagnostic purposes. Materials and Methods: A hybridoma (clone 4D1) secreting anti-HBs IgG2a monoclonal antibody (mAb) was used for the establishment of our in-house ELISA. Tests were performed for both cell culture medium and human sera. The hepatoma cell lines of human origin PLC/PRF/5 and …
Correlations Of Serum Il-6 Levels And Prolidase Activity Between Bone Turnover Markers And Bone Mineral Density In Postmenopausal Women With And Without Osteoporosis, Aysun Toker, Hülya Aksoy, Bünyami̇n Börekçi̇, Asuman Özkan
Correlations Of Serum Il-6 Levels And Prolidase Activity Between Bone Turnover Markers And Bone Mineral Density In Postmenopausal Women With And Without Osteoporosis, Aysun Toker, Hülya Aksoy, Bünyami̇n Börekçi̇, Asuman Özkan
Turkish Journal of Medical Sciences
Aim: The purpose of this study was to measure serum prolidase activity and interleukin-2 and 6 (IL-2, IL-6) levels and to investigate the relationship of these parameters with bone mineral density (BMD) and bone turnover markers in postmenopausal women with and without osteoporosis. Materials and Methods: 59 postmenopausal women were included in this study (21 women with osteoporosis and 38 without). Serum IL-2 and IL-6 levels, prolidase activity, osteocalcin (OSC), calcium (Ca), alkaline phosphatase (ALP), urinary deoxypyridinoline (DPD) and BMD were measured in postmenopausal women with and without osteoporosis. Results: Serum prolidase activity was slightly higher in postmenopausal nonosteoporotic women …
Cobalamin Deficiency During Pregnancy Expressed As Elevated Urine Methylmalonic Acid Levels Determined By A Photometric Assay, Osman Meti̇n İpçi̇oğlu, Mustafa Gültepe, Ömer Özcan
Cobalamin Deficiency During Pregnancy Expressed As Elevated Urine Methylmalonic Acid Levels Determined By A Photometric Assay, Osman Meti̇n İpçi̇oğlu, Mustafa Gültepe, Ömer Özcan
Turkish Journal of Medical Sciences
Aim: Deficiency of cobalamin and folate during pregnancy is associated with megaloblastic anemia. Lower levels of folate and vitamin B12 were reported in mothers whose offspring had neural tube defects compared to unaffected controls. Increased methylmalonic acid (MMA) levels are a sensitive indicator of mild vitamin B12 deficiency and elevated homocysteine levels denote vitamin B12 or folate deficiency. We aimed to evaluate cobalamin state in pregnancy by using urine MMA levels determined by an economic spectrophotometric method. Materials and Methods: For this cross-sectional study, plasma total homocysteine (tHcy), serum folate and vitamin B12, and urine MMA levels were measured in …
Is Serum Prostate Specific Antigen Level Affected By In-And-Out Urethral Catheterization?, Yilmaz Aslan, Altuğ Tuncel, Ümi̇t Tekdoğan, Osman Özergi̇n, Ali̇ Atan
Is Serum Prostate Specific Antigen Level Affected By In-And-Out Urethral Catheterization?, Yilmaz Aslan, Altuğ Tuncel, Ümi̇t Tekdoğan, Osman Özergi̇n, Ali̇ Atan
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to investigate the effect of in-and-out urethral catheterization on serum total and free prostate specific antigen (PSA) levels and free/total PSA ratio. Materials and Methods: This is a prospective study including 24 patients who admitted with lower urinary tract symptoms and underwent in-and-out urethral catheterization with 18 F Foley catheter inserted for postvoiding residual urine measurement. Blood samples were withdrawn to determine serum total and free PSA levels and free/total PSA ratio immediately before, and at 1, 24 and 72 hours after urethral catheterization. Results: There was no alteration in total and free PSA …
Spectrum Of Clinical Infectious Diseases In Hospitalized Elderly Patients In The Southeast Of Iran, Batool Sharifi-Mood, Maliheh Metanat
Spectrum Of Clinical Infectious Diseases In Hospitalized Elderly Patients In The Southeast Of Iran, Batool Sharifi-Mood, Maliheh Metanat
Turkish Journal of Medical Sciences
Aim: The elderly have defective host defenses that compromise their ability to ward off infectious agents; factors influencing immunocompetence include impaired host defenses such as diminished cell-mediated immunity, changes in chronic diseases, medications, malnutrition and functional impairments. This study was conducted in order to determine the pattern of clinical infectious diseases in a series of hospitalized elderly patients. Materials and Methods: In this cross-sectional study, all elderly patients who were admitted to our hospital in Zahedan (Southeast Iran) between 2001 and 2006 were evaluated. We retrospectively reviewed the 1278 patients for diagnostic studies, risk factors, treatment options and morbidity and …
Quality Assurance Standards Task Force Global Standards: Route For Accreditation In Medical Education In Europe, İskender Sayek, Hans Karle
Quality Assurance Standards Task Force Global Standards: Route For Accreditation In Medical Education In Europe, İskender Sayek, Hans Karle
Turkish Journal of Medical Sciences
No abstract provided.
Prevalence Of Lower Urinary Tract Symptoms In Men Over 40 Years: A Cross-Sectional Study In Samsun, Ahmet Tevfi̇k Sünter, Ci̇had Dündar, Sevgi̇ Canbaz, Sennur Dabak, Yildiz Pekşen
Prevalence Of Lower Urinary Tract Symptoms In Men Over 40 Years: A Cross-Sectional Study In Samsun, Ahmet Tevfi̇k Sünter, Ci̇had Dündar, Sevgi̇ Canbaz, Sennur Dabak, Yildiz Pekşen
Turkish Journal of Medical Sciences
Aim: Lower urinary tract symptoms (LUTS) are a common problem in ageing men. The aim of this study was to estimate the prevalence of LUTS, as measured by the International Prostate Symptom Score (IPSS), and to establish the relationship between the IPSS and quality of life (QoL) in different age groups of men over 40 years old living in Samsun city center in northern Turkey. Materials and Methods: In all, 1860 men aged over 40 years were included in this cross-sectional study. The Turkish version of the IPSS was applied to all participants using face-to-face interview. Results: The median IPSS …
Anesthesia For An Adult Patient With Congenital Diaphragmatic Eventration, Hale Yarkan Uysal, Solmaz Günal, Ahmet Ş. Uyar, Hülya Başar
Anesthesia For An Adult Patient With Congenital Diaphragmatic Eventration, Hale Yarkan Uysal, Solmaz Günal, Ahmet Ş. Uyar, Hülya Başar
Turkish Journal of Medical Sciences
Congenital diaphragmatic eventration is an uncommon condition in adults and is defined as an abnormal elevation of the diaphragm. In adults, diaphragmatic eventration causes respiratory impairment that is associated with severe dyspnea, orthopnea and hypoxia. Most of the symptomatic patients may survive with supportive therapy without any need for surgical correction, though they are at risk of spontaneous diaphragm rupture. Spontaneous diaphragmatic rupture may develop in a patient with diaphragmatic eventration as a result of any event that leads to increase in intraabdominal pressure. In this case report, we present the anesthetic management of an adult patient with congenital diaphragmatic …
Effect Of Different Drugs Influencing Monoamine Neurotransmission On Haloperidol-Induced Catalepsy In Mice, Omar Mohamed Abdel-Salam, Ayman Ragab Baiuomy
Effect Of Different Drugs Influencing Monoamine Neurotransmission On Haloperidol-Induced Catalepsy In Mice, Omar Mohamed Abdel-Salam, Ayman Ragab Baiuomy
Turkish Journal of Medical Sciences
Aim: Catalepsy occurs following high dopamine D2 receptor blockade by the typical antipsychotic drug haloperidol. The present study investigated the effect of different drugs affecting monoamine neurotransmission in this animal model of Parkinson's disease in mice. Materials and Methods: Drugs were intraperitoneally administered with haloperidol 30 min prior to testing. Catalepsy was measured using the bar test. Results: Catalepsy duration was reduced by the non-selective noradrenaline and serotonin reuptake inhibitors imipramine and amitriptyline (21.1% and 22.3% reduction by 20 mg/kg imipramine and amitriptyline, respectively). Catalepsy duration was increased by the selective serotonin reuptake inhibitors (SSRIs) fluoxetine, fluvoxamine, and citalopram and …
Autopsy Status And Pathologists’ Attitude Towards Autopsy In Turkey, Kemal Kösemehmetoğlu, Ali̇ Riza Tümer, Alp Usubütün
Autopsy Status And Pathologists’ Attitude Towards Autopsy In Turkey, Kemal Kösemehmetoğlu, Ali̇ Riza Tümer, Alp Usubütün
Turkish Journal of Medical Sciences
Aim: While there have been efforts to slow the recent declining trend in autopsy practice in the world, in Turkey there is already a low level of medical autopsy audit, practically nearing zero. In this study, we determine and evaluate the autopsy status in Turkey; reveal pathologists' attitudes towards autopsy practice; propose several factors to explain current autopsy audit; and discuss differences in Turkey's autopsy practice with that of the rest of the world. Materials and Methods: We directed a questionnaire to 85 pathologists and requested autopsy numbers from 50 universities for the period 1995 to 2003. Results: Mean values …
New Replacement Of A Thrombosed Mitral Valve Via Right Anterolateral Thoracotomy In A Patient With Coronary Artery By-Pass Graft And Functioning Internal Mammary Artery Graft, Münacetti̇n Cevi̇z, Neci̇p Beci̇t, Bi̇lgehan Erkut, Hi̇kmet Koçak
New Replacement Of A Thrombosed Mitral Valve Via Right Anterolateral Thoracotomy In A Patient With Coronary Artery By-Pass Graft And Functioning Internal Mammary Artery Graft, Münacetti̇n Cevi̇z, Neci̇p Beci̇t, Bi̇lgehan Erkut, Hi̇kmet Koçak
Turkish Journal of Medical Sciences
A 49-year-old male, who had undergone mitral valve replacement with mechanical cardiac valve and coronary arterial by-pass grafting six years previously, was admitted to our hospital with acute dyspnea. Transesophageal echocardiography revealed that one of the leaflets of the prosthetic valve was entirely immobilized in the closed position, and an immobile soft tissue mass was detected on the ventricular side of the obstructed leaflet. We performed re-replacement using a 29-mm mechanical prosthetic St. Jude valve under deep hypothermic circulatory arrest via right atrial thoracotomy. Postoperative course was uneventful, and the patient was discharged with oral anticoagulant therapy on day 7 …
Effects Of Exercise On Hemorheological Parameters Of Young Nigerian Smokers, Omolade Augustina Awodu, Ademola Adekunle Famodu
Effects Of Exercise On Hemorheological Parameters Of Young Nigerian Smokers, Omolade Augustina Awodu, Ademola Adekunle Famodu
Turkish Journal of Medical Sciences
Aim: Regular physical exercise is associated with reduced risk of cardiovascular diseases. In this study, the hypothesis that acute submaximal exercise has similar effects on rheological parameters of smokers and non-smokers was tested. Materials and Methods: Thirty-three male university undergraduates comprised of 18 smokers and 15 non-smokers were studied. All the subjects underwent submaximal exercise on cycloergometer for 30 minutes. Blood for hemorheological parameters was collected 30 minutes before and after exercise. Samples were analyzed by standard methods. Results: A total of 33 undergraduates were studied. The hematocrit, plasma viscosity and plasma fibrinogen were significantly higher in smokers than non-smokers …
The Distribution Of Bone Mineral Density In Healthy Women In Tehran, Hadi̇ Akhbari
The Distribution Of Bone Mineral Density In Healthy Women In Tehran, Hadi̇ Akhbari
Turkish Journal of Medical Sciences
Aim: Correct interpretation of Bone Mineral Densitometry (BMD) measurements requires a population-specific reference range. The aim of this study was to establish Dual Energy X-ray Absorptiometry (DEXA) BMD reference values for healthy women residing in Tehran. Materials and Methods: 566 healthy female volunteers aged 20-40 years from five district areas in Tehran participated in the study. BMD was determined by a LUNAR system. Measurement sites were the spine, femur, leg, arm, pelvis and total body. All measurements were performed by an experienced staff. Prior to each measurement, quality control testing was performed by using the spine phantom of known density. …
Comparison Of Conventional Cytogenetic And Fluorescence In Situ Hybridization Results Of Prenatal Aneuploidy Screening, Zerri̇n Yilmaz, Özge Özalp, Ebru Tarim, Ayla Üçkuyu, Vural Dağli, Feri̇de İffet Şahi̇n
Comparison Of Conventional Cytogenetic And Fluorescence In Situ Hybridization Results Of Prenatal Aneuploidy Screening, Zerri̇n Yilmaz, Özge Özalp, Ebru Tarim, Ayla Üçkuyu, Vural Dağli, Feri̇de İffet Şahi̇n
Turkish Journal of Medical Sciences
Background and Aim: Prenatal diagnosis of chromosome abnormalities is usually performed on amniotic fluid samples. Aneuploidy screening by fluorescence in situ hybridization (FISH), although not an alternative for conventional cytogenetics, has become a useful tool. Materials and Methods: We compared the results of FISH and conventional cytogenetic analysis applied on 51 amniotic fluid samples between January 2002 and December 2005, in our Cytogenetics Laboratory. Amniocytes were extracted using 5 cc of the sample, and direct FISH was applied using an AneuVysion Assay Kit (Vysis). The remaining fluid samples were used for chromosome analysis by conventional methods after long-term cell cultures. …
A Copper Determination Method Based On The Reaction Between 2-(5-Nitro-2-Pyridylazo)-5-(N-Propyl-N- Sulfopropylamino) Phenol (Nitro-Paps) And Copper For Use In Urine Copper Measurement And Application To Automation, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe
A Copper Determination Method Based On The Reaction Between 2-(5-Nitro-2-Pyridylazo)-5-(N-Propyl-N- Sulfopropylamino) Phenol (Nitro-Paps) And Copper For Use In Urine Copper Measurement And Application To Automation, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe
Turkish Journal of Medical Sciences
Aim: To develop a sensitive automated colorimetric urine copper determination method using a water soluble compound, 2-(5-nitro-2-pyridylazo)-5-(N-propyl-N-sulfopropylamino) phenol (nitro-PAPS), as a ligand. Materials and Methods: The new photometric method using sodium dodecyl sulfate (SDS)-ascorbic acid to dissociate copper from proteins in acetate buffer (pH 3.2) and nitro-PAPS as ligand was also adapted to an automated analyzer. Copper concentrations were determined by atomic absorption spectrophotometric method and by photometric method in 24 h urine samples of patients (n = 100) with various types of diseases including Wilson's disease (n = 12), diabetes mellitus (n = 34), osteoporosis (n = 27), nephrotic …
Editorial, M. Mahi̇r Özmen
Evaluation Of The Ehrlich-Ziehl-Neelsen (Ezn) And Amplified Mycobacterium Tuberculosis Direct Test According To The Bactec Method In Respiratory And Nonrespiratory Samples, Tuncer Özeki̇nci̇, Sevi̇m Meşe, Selahatti̇n Atmaca, Nezahat Akpolat, Kadri̇ Gül
Evaluation Of The Ehrlich-Ziehl-Neelsen (Ezn) And Amplified Mycobacterium Tuberculosis Direct Test According To The Bactec Method In Respiratory And Nonrespiratory Samples, Tuncer Özeki̇nci̇, Sevi̇m Meşe, Selahatti̇n Atmaca, Nezahat Akpolat, Kadri̇ Gül
Turkish Journal of Medical Sciences
Aim: Tuberculosis remains a significant and threatening disease, particularly in developing countries. Mycobacterium tuberculosis should be detected and identified as soon as possible to ensure the prevention of the spread of the disease. For this purpose, use of fast and reliable laboratory diagnostic methods with high sensitivity and specificity was initiated in recent years. Materials and Methods: In this study, 107 respiratory and 198 nonrespiratory (305 in total) samples submitted to Dicle University Faculty of Medicine Clinical Microbiology Laboratory were examined using the Ehrlich-Ziehl-Neelsen (EZN), BACTEC 460 TB (Becton and Dickinson Diagnostic Instrument System, Towson, MD), and MTD (Amplified Mycobacterium …
A Rare Side Effect Of Metformin: Metformin-Induced Hepatotoxicity, Ersi̇n Aksay, Sedat Yanturali, Başak Bayram, Ni̇l Hocaoğlu, Selahatti̇n Kiyan
A Rare Side Effect Of Metformin: Metformin-Induced Hepatotoxicity, Ersi̇n Aksay, Sedat Yanturali, Başak Bayram, Ni̇l Hocaoğlu, Selahatti̇n Kiyan
Turkish Journal of Medical Sciences
Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.